Publications

isolation of dermatophytes, candida species and systemic fungi from dermatologic specimens in montréal, 1963 to 1973.	of 10 057 specimens of scrapings from skin, nails and scalp examined for dermatophytes, yeasts, pityriasis versicolor and systemic mycoses between 1963 and 1973, 30.4 percent were positive for fungi. skin produced the highest proportion (68.6 percent) of positive scrapings, scalp the lowest (4.2 percent). trichophyton rubrum was the predominant species (23.6 percent); of lesser prevalence were microsporum canis (9.3 percent), t. mentagrophytes (8.4 percent) and epidermophyton floccosum (4.8 perc ...	1975	1091342
fatty acids of epidermophyton floccosum (harz) langeron and milochevitch.		1976	1004524
miconazole in the treatment of superficial mycoses.	miconazole nitrate (2%) cream was evaluated in the treatment of superficial mycoses. out of 116 patients having multiple clinical diagnoses, 66 cases were found to be positive by culture. species of trichophyton were the predominant etiological agents (in over 60%) followed by candida species (20%) and epidermophyton floccosum (15%). all the cases selected for study were followed up to a period of 4-18 months. a cure rate of 94.6 per cent was observed in all the cases where causal organisms were ...	1976	967228
studies on the biological effects of deuteriated organic compounds. ii. morphological changes of epidermophyton floccosum exposed to perdeuteriated n-hendecanoic acid studied with interference contrast and scanning electron microscopy.	in order to visualise the morphological changes of epidermophyton floccosum associated with exposure to perdeuteriated n-hendecanoic acid, the architecture of the dermatophyte was investigated by means of interference contrast and scanning electron microscopy. the morphology of mycelia grown on substrate containing perdeuteriated n-hendecanoic acid, or the unlabelled analogue, was compared. the perdeuteriated n-hendecanoic acid produced a characteristic undulant effect of the hyphae. the charact ...	1976	967224
studies on the biological effects of deuteriated organic compounds. i. antifungal activity of perdeuteriated fatty acids on dermatophytes in vitro.	the antifugal activity of some perdeuteriated fatty acids, with normal chain 11 to 18 carbon atoms, was investigated on common dermatophytes epidermophyton floccosum, microsporum canis, trichophyton mentagrophytes and t. rubrum under in vitro conditions. these studies were performed by dilution technique and with respiratory measurements, perdeuteriation of some fatty acids increases their inhibitory effect on the dermatophyte growth. perdeuteriated n-hendecanoic acid proved to be the most activ ...	1976	967223
isolation of a peptido-polysaccharide from the dermatophyte epidermophyton floccosum and a study of its reaction with human c-reactive protein and a mouse anti-phosphorylcholine myeloma serum.	culture filtrate extracts from a number of dermatophyte and aspergillus species precipitate with human c-reactive protein (crp) and the lectin con a. using immobilized con a, a peptidopolysaccharide (pps) has been isolated from epidermophyton floccosum culture filtrate by affinity chromatography and shown to precipitate with con a, human crp sera and a mouse myeloma serum with specificity for phosphorylcholine (pc). the pps contains carbohydrate (60%), protein (35%), choline and phosphate. the c ...	1977	885587
production of elastase, urease and sulphatase by epidermophyton floccosum (harz) langeron et milochevitch (1930).		1977	865508
ringworm on the scalp due to epidermophyton floccosum.		1977	862222
lymphocyte transformation in vitro in dermatophytosis.	peripheral blood lymphocytes from 59 patients with dermatophytosis and from nine young healthy women were studied by the lymphocyte transformation test (lt) using mitogens and bacterial as well as fungal antigens. the latter included candida albicans (ca) and four dermatophyte species, viz. trichophyton rubrum (tr), trichophyton mentagrophytes (tm), epidermophyton floccosum (ef) and microsporum canis (mf). most of the patients showed normal transformation in response to mitogens and non-dermatop ...	1976	793301
isolation of ethyl p-methoxycinnamate, the major antifungal principle of curcumba zedoaria.	an antifungal principle of the dried rhizomes of curcuma zedoaria was extracted with hot ethanol. by successive chromatography on neutral alumina and silica gel, three antibiotic compounds a, b, and c, all active against trichophyton rubrum, aspergillus niger and saccharomyces cerevisiae, were obtained in chemically pure form. by uv, ir, pmr and ms analysis, the structure of the most abundant one of these compounds (c, 69.8%; h, 6,8%; and 0.23.4%) was assigned as ethyl p-methoxycinnamate (epmc). ...	1976	785141
tinea cruris: diagnostic confusion due to isolation of candida albicans alone.	the diagnostic importance of the isolation of candida albicans from a skin lesion is often uncertain. in a 68-year-old man from whose lesions only c. albicans was originally isolated trichophyton rubrum and epidermophyton floccosum were also isolated when the growth of the yeast was inhibited in a selective medium. the use of this selective medium, casamino acids erythritol albumin agar, ensures the proper interpretation of the significance of the presence of c. albicans in skin lesions.	1976	773524
clinical evaluation of clotrimazole. a broad-spectrum antifungal agent.	the efficacy and safety of the broad-spectrum, topically applied antifungal agent clotrimazole were evaluated in two double-blind, multicentric trials. ten investigators reported on a total of 1,361 cases in which a 1% solution or a 1% cream formulation was compared with its respective vehicle. clotrimazole was therapeutically effective, as confirmed by mycological cure (negative microscopy and culture) and clinical improvement, in tinea pedis, tinea cruris, tinea corporis, pityriasis versicolor ...	1976	769697
storage of epidermophyton floccosum at-22 c.		1978	723916
comparison of the in vitro antifungal activities of miconazole and a new imidazole, r41,400.	r41,400 is a recently synthesized, water-soluble imidazole. its antifungal properties were compared in vitro with those of miconazole using an agar dilution procedure and 175 isolates of human fungal pathogens. the filamentous forms of histoplasma capsulatum and blastomyces dermatitidis were inhibited by less than or equal to 2 microgram of either drug/ml; coccidioides immitis was inhibited by less than or equal to 0.5 microgram of r41,400/ml. among the yeasts tested, cryptococcus neoformans and ...	1978	681800
antibiotic production by dermatophyte fungi.	thirty-two clinical isolates of anthropophlic dermatophytes were examined for their capacity to produce antibiotics in liquid culture and on human stratum corneum in vitro. antibiotics were detected and classified using agar diffusion bioassays and chromatographic analysis. twenty-four isolates produced antibiotic substances in liquid culture filtrates; some strains produced more than one antibiotic. only four isolates produced detectable levels of antibiotics when grown on stratum corneum unles ...	1978	632806
membrane ultrastructure of hyphae of epidermophyton floccosum: as observed by freeze-fracture electron microscopy.		1977	604412
dermatophytosis survey in lagos state of nigeria.	a dermaphytosis survey covering 3,860 schoolchildren was conducted in lagos, nigeria, between january 1973 and january 1974. seven species of dermatophytes, namely, trichophyton mentagrophytes (four isolates), t. rubrum (three isolates), t. soundanense (11 isolates), microsporum canis (five isolates), m. gypseum (two isolates), m audouinii (four isolates), and epidermophyton floccosum (three isolates) were recovered from specimens collected from the hair, skin and scalp scrapings of 81 schoolchi ...	1977	595081
epidemiologic study of dermatophytoses in salamanca (spain).	an epidemiologic study of the dermatophytoses in salamanca (spain) from 1973 to 1976 was performed. dermatophyte species were identified in 224 patients with clinical tinea infections; 31 bovines, 18 rodents and 70 soil samples. the prevalence of trichophyton verrucosum and epidermophyton floccosum was strikingly high in relation to other statistics. the most common clinical forms were tinea corporis and tinea cruris. tinea capitis by anthropophilic species was uncommon.	1979	542885
an unusual lipid in the human pathogenic fungus epidermophyton floccosum.	the dermatophyte epidermophyton floccosum contains an unusual lipid characterized as 1(3),2-diacylglyceryl-3(1)-o-4'-(n,n,n-trimethyl)homoserine. its concentration in e. floccosum is approx. 15% of the polar lipids. the role of this lipid in the biosynthesis of polar lipids and fatty acids is not yet known. however, it is interesting from a chemotaxonomic viewpoint that the lipids from two other genera of dermatophyte, microsporum cookei and trichophyton rubrum do not contain this novel lipid.	1979	486519
dermatophyte species, microscopic and cultural examination.	the dermatophytes epidermophyton floccosum, microsporum canis, trichophyton mentagrophytes var. interdigitale, t. rubrum, and t. verrucosum were compared with respect to the direct microscopic examination of a clinical material and the number of colonies obtained by culture. it was found that the results of microscopy as well as of culture depended to a marked extent upon which species were the cause of the mycosis. the extremes were e. floccosum and t. mentagrophytes var. interdigitale which sh ...	1979	481562
phospholipids of epidermophyton floccosum.		1979	429049
comparison of in vitro activity of undecylenic acid and tolnaftate against athlete's foot fungi.	undecylenic acid and tolnaftate were tested in an in vitro test system to evaluate their relative "killing time" efficacy against trichophyton mentagrophytes, trichophyton rubrum, and epidermophyton floccosum. commercial products containing these active agents were tested similarly. the pure active agents were equivalent in activity. the commercial product containing undecylenic acid appeared to be more effective against the test organisms than did the product containing tolnaftate.	1979	423138
[in vitro effectiveness of salicylic, benzoic and boric acid and diiodine thymol solutions on various strains of dermatophytes].	in order to study the in vitro behavior of the drug used according to our formula cultures of trichophyton mentagrophytes. trichophyton rubrum, trichophyton verrucosum, trichophyton tonsurans, microsporum canis, microsporum gallinae, microsporum audouinii, microsporum gypseum and epidermophyton floccosum were prepared in order to prove its efficacy. it was found no growth in cultures to which the drug was added in different concentrations thus proving its efficacy as a fungistatic element. the i ...	1979	395583
[ultrastructure of hyphal walls of epidermophyton floccosum as observed by freeze-fracture electron microscopy: with special reference to the outer most layer ("exo-layer") of the cell wall (author's transl)].		1979	311868
[randomised investigations of some tyrolean swimming pools for the presence of trichomonas vaginalis and pathogenic fungi (author's transl)].	trichomonads were not demonstrated either microscopically or by culture in water samples from 15 public open air swimming pools in the tyrol. on the other hand, a small number of pathogenic fungi (candida albicans, trichophyton mentagrophytes, tr. verrucosum) were cultured from pool water with a free chlorine content of less than 0.35 mg/l (dpd 1). dermatophytes could also be demonstrated by cultures of the coatings on the surfaces of tiles in the showers, and of pool surrounding-and cabin tract ...	1975	239503
fungal diseases in shiraz.	in 122 patients with fungal diseases studied over a six month period, sixty were seen with dermatophyte infections. tinea pedis, cruris and ungruium occurred mainly in adult males attending the private hospital and tinea corporis and capitis children attending the university hospital. the organisms found were trichophyton rubrum, t. mentagrophytes, t. schonleinii, t. tonsurans, epidermophyton floccosum and microsporum canis. infections with candida albicans occurred both in the urban and rural p ...	1978	148630
[epidemiology and clinical aspects of a mycosis caused by epidermophyton floccosum].		1976	139790
[localization of solitary dermatophytic lesions in man].	the occurrence of three causative organisms of the so called intertriginous dermatophytoses--epidermophyton floccosum, trichophyton mentagrophytes var. interdigitale and t. rubrum--was compared according to the localization of the lesions. the differentiation of invasion into solitary and combined sites showed a prevalence of e. floccosum in solitary lesions and t. rubrum in combined lesions. in t. mentagrophytes var. interdigitale, the frequency of occurrence of both types of the lesions was ap ...	1975	126977
[epidermophyton floccosum (harz) langeron et milochevitch in eastern bohemia (author's transl)].		1975	124225
the clinical significance of cutaneous reactions to trichophytin in dermatophytosis.	an intracutaneous test was performed in 114 patients with dermatophytosis verified by culture and in 32 control subjects, unsing purified trichophytin (according to the ethylene glycol method) and commercially available trichophytin. immediate reactions occurred with both trichophytin antigens at a similar frequency in 12-14% of cases. delayed reactions occurred significantly more often to the purified trichophytin in patients with dermatophytosis (36%) but in none of the controls. immediate rea ...	1978	76393
studies of the antigenic structure of trichophyton rubrum, trichophyton mentagrophytes, microsporon canis, and epidermophyton floccosum by crossed immuno-electrophoresis.	by means of crossed immuno-electrophoresis, 35 antigens of t. rubrum, 26 of t. mentagrophytes, 35 of m. canis, and 25 of e. floccosum have been demonstrated. tandem crossed immuno-electrophoresis has revealed two antigens common to t. rubrum and the other species, which, however, differ within the species. no common antigens have been demonstrated between t. mentagrophytes, m. canis, and e. floccosum. the technique for preparation of extracts and production of immune serum is described, and the ...	1976	60875