Publications
Title | Abstract | Year Filter | PMID(sorted descending) Filter |
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inactivation of p53 is insufficient to allow b cells and b-cell lymphomas to survive without dicer. | inactivation of p53, the master regulator of cellular stress and damage signals, often allows cells that should die or senesce to live. loss of dicer, an rnase iii-like enzyme critical in microrna biogenesis, causes embryonic lethality and activation of the p53 pathway. several nonhematopoietic cell types that contain inactivated p53 have been shown to survive dicer deletion, suggesting that p53 loss may protect cells from the negative consequences of dicer deletion. however, here, we report tha ... | 2014 | 24840646 |
[activators, receptors and signal transduction pathways of blood platelets]. | platelet participation in hemostatic plug formation requires transition into an activated state (or, rather, variety of states) upon action of agonists like adp, thromboxane a , collagen, thrombin, and others. the mechanisms of action for different agonists, their receptors and signaling pathways associated with them, as well as the mechanisms of platelet response inhibition are the subject of the present review. collagen exposed upon vessel wall damage induced initial platelet attachment and st ... | 2014 | 24837309 |
gas phase preparation of spherical core-shell α''-fe16n2/sio2 magnetic nanoparticles. | well-dispersed spherical core-shell α''-fe16n2/sio2 ferro-magnetic nanoparticles were successfully synthesized from core-shell α-fe/sio2 nanoparticles. introduction of oxidation prior to the nitridation process gives 90% of α''-fe16n2 phase contained in the core while no phase change is observed without oxidation. saturation magnetization and coercivity are 148 emu g(-1) and 1.82 koe, respectively. | 2014 | 24834445 |
genomic support for a moa-tinamou clade and adaptive morphological convergence in flightless ratites. | one of the most startling discoveries in avian molecular phylogenetics is that the volant tinamous are embedded in the flightless ratites, but this topology remains controversial because recent morphological phylogenies place tinamous as the closest relative of a monophyletic ratite clade. here, we integrate new phylogenomic sequences from 1,448 nuclear dna loci totaling almost 1 million bp from the extinct little bush moa, chilean tinamou, and emu with available sequences from ostrich, elegant ... | 2014 | 24825849 |
biochemical and functional characterization of transiently expressed in neural precursor (tenp) protein in emu egg white. | a protein transiently expressed in the neural precursors of developing tissues (tenp) was found to be present in emu (dromaius novaehollandiae) egg white as one of the major proteins. nucleotide analysis of its encoding cdna revealed a sequence of 452 amino acids including a 19 amino acid peptide signal. phylogenetic analysis determined that emu tenp was clustered within the bactericidal/permeability-increasing protein (bpi) superfamily together with other avian tenps. rt-pcr analysis revealed t ... | 2014 | 24820544 |
occurrence of fatal syngamosis in emu birds of kerala. | two male and two female emu birds of 8 months to 1 year old reared in a private farm were brought dead to college of veterinary and animal sciences, pookode for postmortem examination during the period from july to september, 2010. the birds were emaciated and drooling of blood from the mouth was observed for 2 days prior to death. postmortem examination of the dead birds revealed occurrence of large numbers of red coloured worms throughout trachea with histopathological changes. the worms were ... | 2014 | 24808660 |
facile preparation of core-shell magnetic metal-organic framework nanospheres for the selective enrichment of endogenous peptides. | facile preparation of core-shell magnetic metal-organic framework nanospheres by a layer-by-layer approach is presented. the nanospheres have high surface area (285.89 cm(2) g(-1)), large pore volume (0.18 cm(3) g(-1)), two kinds of mesopores (2.50 and 4.72 nm), excellent magnetic responsivity (55.65 emu g(-1)), structural stability, and good dispersibility. the combination of porosity, hydrophobicity, and uniform magnetism was exploited for effective enrichment of peptides with simultaneous e ... | 2014 | 24807292 |
chronic lymphocytic leukemia cells in a lymph node microenvironment depict molecular signature associated with an aggressive disease. | chronic lymphocytic leukemia (cll) cells survive longer in vivo than in vitro, suggesting that the tissue microenvironment provides prosurvival signals to tumor cells. primary and secondary lymphoid tissues are involved in the pathogenesis of cll, and the role of these tissue microenvironments has not been explored completely. to elucidate host-tumor interactions, we performed gene expression profiling (gep) of purified cll cells from peripheral blood (pb; n = 20), bone marrow (bm; n = 18), and ... | 2014 | 24800836 |
technical tips: event testing in the epilepsy monitoring unit. | event testing plays an important role in the determination of event type. this is true for epileptic and/or nonepileptic events. any individuals who spend a significant amount of time in a patient's room can contribute to this important part of an admission to the epilepsy monitoring unit (emu). what follows is an explanation outlining the purpose of event testing and some suggestions on how to do it effectively. the nurses and support staff on the floor are usually the "first ones there." prope ... | 2014 | 24783752 |
comparative distribution and arrangement of herbst corpuscles in the oropharynx of the ostrich (struthio camelus) and emu (dromaius novaehollandiae). | herbst corpuscles are widely distributed throughout the oropharynx of the ostrich and emu in contrast to the general situation in birds. knowledge of the comparative distribution of herbst corpuscles in the oropharynx of these two commercially important ratite species may assist in a better understanding of their feeding habits. tissue sections representing all parts of the oropharynx of five ostrich and five emu heads collected after slaughter were prepared for light microscopy, the herbst corp ... | 2014 | 24782341 |
application of hydrophobically modified water-soluble polymers for the dispersion of hydrophobic magnetic nanoparticles in aqueous media. | hydrophobically modified water-soluble polymers (hmwsps), comprised of a poly(sodium methacrylate) (pmana) or poly(sodium acrylate) (pana) backbone and pendent dodecyl methacrylate (dma) or dodecyl acrylamide (daam) chains, respectively, were synthesized. the hydrophobic content of the copolymers, p(mana-co-dma) and p(ana-co-daam), is in the range of 0 to 25 mol%, while their weight-average molar mass varies from ~10 000 up to ~75 000. their self-assembly behavior in dilute aqueous solution was ... | 2014 | 24759871 |
surface-functionalized hyperbranched poly(amido acid) magnetic nanocarriers for covalent immobilization of a bacterial γ-glutamyltranspeptidase. | in this study, we synthesized water-soluble hyperbranched poly(amido acid)s (hbpaas) featuring multiple terminal co2h units and internal tertiary amino and amido moieties and then used them in conjunction with an in situ fe2+/fe3+ co-precipitation process to prepare organic/magnetic nanocarriers comprising uniformly small magnetic iron oxide nanoparticles (np) incorporated within the globular hbpaas. transmission electron microscopy revealed that the hbpaa-γ-fe2o3 nps had dimensions of 6-11 nm, ... | 2014 | 24759067 |
fabrication of fluorescent magnetic fe3o4@zns nanocomposites. | a novel fe3o4@zns nanomaterial with fluorescent and superparamagnetic properties has been successfully fabricated via topo-top synthesis with an additional coordinating component (oam). the adsorption of oam on the preformed magnetite nanoparticles, which were prepared in phenyl ether with oleic acid and oleyl amine, played an essential role in directing the structure of the fe3o4@zns composites. the obtained materials were characterized by ftir, tem, xrd, x-ray photoelectron spectroscopy (xps), ... | 2014 | 24757979 |
magnetic activated carbon-fe3o4 nanocomposites--synthesis and applications in the removal of acid yellow dye 17 from water. | in this work, synthesis of activated carbon-fe3o4 composites using activated carbon and iron benzoate/oxalate precursors by simple pyrolytic method and its utility for the removal of acid yellow dye from water are presented. iron carboxylates held up into the pores of carbon dissociate at their decomposition temperatures form dispersed fe3o4 nanoparticles in carbon matrix. the composites were characterized by ftir, pxrd, sem, tem, edx and magnetization measurements. the size of the nano iron oxi ... | 2014 | 24757966 |
3-substituted-n-(4-hydroxynaphthalen-1-yl)arylsulfonamides as a novel class of selective mcl-1 inhibitors: structure-based design, synthesis, sar, and biological evaluation. | mcl-1, an antiapoptotic member of the bcl-2 family of proteins, is a validated and attractive target for cancer therapy. overexpression of mcl-1 in many cancers results in disease progression and resistance to current chemotherapeutics. utilizing high-throughput screening, compound 1 was identified as a selective mcl-1 inhibitor and its binding to the bh3 binding groove of mcl-1 was confirmed by several different, but complementary, biochemical and biophysical assays. guided by structure-based d ... | 2014 | 24749893 |
preparation of alpha-fe2o3 nanotubes by calcination of electrospun precursors. | the alpha-fe2o3 nanotubes with diameters of 400-700 nm were prepared by calcination of electrospun precursors. the morphology of alpha-fe2o3 nanotubes is mainly influenced by the water content in solution and heating rate during the calcination process. when the water content is about 17 wt.%, heating rate is 5 degrees c/min and calcination temperature at 500 degrees c for 2 h, the optimized alpha-fe2o3 nanotubes are obtained. these alpha-fe2o3 nanotubes have a magnetization (m(s)) of 0.36 emu x ... | 2014 | 24745283 |
optical and magnetic properties of co-doped cuo flower/plates/particles-like nanostructures. | in this study, pure and co-doped cuo nanostructures (0.5, 1.0, 1.5, and 2.0 at wt% of co) were synthesized by microwave combustion method. the prepared samples were characterized by x-ray diffraction (xrd), high resolution scanning electron microscopy (hr-sem), energy dispersive x-ray analysis (edx), diffuse reflectance spectroscopy (drs), photoluminescence (pl) spectroscopy and vibrating sample magnetometry (vsm). powder x-ray diffraction patterns refined by the rietveld method indicated the fo ... | 2014 | 24745266 |
the inhibitory and apoptotic effects of docetaxel-loaded mesoporous magnetic colloidal nanocrystal clusters on bladder cancer t24 cells in vitro. | mesoporous magnetic colloidal nanocrystal clusters (mcncs) are featured with high magnetization, adequate surface area, excellent colloidal stability, good biocompatibility, and acid degradability. it is thus highly anticipated that mcncs can serve as vehicles for target drug delivery. herein, the mesoporous mcncs stabilized by poly(gamma-glutamic acid) (pga) were fabricated by the modified solvothermal route, showing a high specific surface area (126.4 m2/g), strong magnetic response (63 emu/g) ... | 2014 | 24730241 |
preparation and characterization of an amphipathic magnetic nanosphere. | the amphipathic magnetic nanospheres were synthesized using c8 and polyethylene glycol as ligands. their morphology, structure, and composition were characterized by transmission electron microscope, fourier transform infrared, and elementary analysis. the prepared materials presented uniform sphere with size distribution about 200 nm. the magnetic characteristics of magnetic nanomaterials were measured by vibrating sample magnetometer. the target products had a saturation magnetization value of ... | 2014 | 24729917 |
pathological and biochemical studies of mucopolysaccharidosis type iiib (sanfilippo syndrome type b) in juvenile emus (dromaius novaehollandiae). | mucopolysaccharidosis (mps) type iiib was diagnosed in 14 juvenile emus (dromaius novaehollandiae), ages 3 weeks to 6 months, based on pathological and biochemical analyses. the animals had a history of neurological signs or sudden death; one of the birds with neurological signs and 3 others experienced acute hemoabdomen. histopathologically, neuronal swelling and vacuolation in the cerebrum, cerebellum, brainstem, and spinal cord (80%-92%); retina (100%); autonomic ganglia of the intestine (71% ... | 2015 | 24723233 |
preparation and evaluation of the effect of fe3 o4 @piroctone olamine magnetic nanoparticles on matrix metalloproteinase-2: a preliminary in vitro study. | in the present study, fe3 o4 magnetic nanoparticles were synthesized by the coprecipitation of fe(2+) and fe(3+) ions and used as a nanocarrier for the production of piroctone-olamine-loaded fe3 o4 nanoparticles (fe3 o4 @po nps). the nanocrystalline structure of the prepared iron oxide species was confirmed by the x-ray diffraction spectroscopy method. particle size distribution analysis showed that the size of fe3 o4 @po nps was in the range of 5-55 nm. the magnetization curve of fe3 o4 @po nps ... | 2015 | 24716879 |
superparamagnetic nanoparticle delivery of dna vaccine. | the efficiency of delivery of dna vaccines is often relatively low compared to protein vaccines. the use of superparamagnetic iron oxide nanoparticles (spions) to deliver genes via magnetofection shows promise in improving the efficiency of gene delivery both in vitro and in vivo. in particular, the duration for gene transfection especially for in vitro application can be significantly reduced by magnetofection compared to the time required to achieve high gene transfection with standard protoco ... | 2014 | 24715289 |
role of vanadium ions, oxygen vacancies, and interstitial zinc in room temperature ferromagnetism on zno-v2o5 nanoparticles. | in this work, we present the role of vanadium ions (v+5 and v+3), oxygen vacancies (vo), and interstitial zinc (zni) to the contribution of specific magnetization for a mixture of zno-v2o5 nanoparticles (nps). samples were obtained by mechanical milling of dry powders and ethanol-assisted milling for 1 h with a fixed atomic ratio v/zn?=?5% at. for comparison, pure zno samples were also prepared. all samples exhibit a room temperature magnetization ranging from 1.18?×?10-3 to 3.5?×?10-3 emu/gr. p ... | 2014 | 24708614 |
influence of reduction temperature on composition, particle size, and magnetic properties of cofe alloy nanomaterials derived from layered double hydroxide precursors. | individual cofe alloy nanoparticles and cofe-mgo nanocomposites were prepared through thermal reduction of single-source layered double hydroxide (ldh) precursors at various temperatures. the samples were characterized by x-ray diffraction (xrd), scanning electron microscopy (sem), transmission electron microscopy (tem), and vibrating sample magnetometer (vsm) analyses to investigate the influence of reduction temperature on the composition, particle size and size distribution, as well as the ma ... | 2014 | 24695765 |
doxorubicin-conjugated core-shell magnetite nanoparticles as dual-targeting carriers for anticancer drug delivery. | the present study reports the successful synthesis of core-shell nanostructures composed of magnetite nanoparticles (fe3o4-nps) conjugated to the anticancer drug doxorubicin, intended for dual targeting of the drug to the tumor sites via a combination of the magnetic attraction and the ph-sensitive cleavage of the drug-particle linkages along with a longer circulation time and reduced side effects. to improve the carrier biocompatibility, the prepared nanocarrier was, finally coated by chitosan. ... | 2014 | 24675279 |
phylogenetic relationships of the australian oligo-miocene ratite emuarius gidju casuariidae. | in australia, ratites (aves: palaeognathae) are represented in the extant fauna by the family casuariidae with 1 species of emu dromaius novaehollandiae and 1 cassowary casuarius casuarius. the australian fossil record reveals no other extinct ratite families but there are a number of other casuariid species. most significant of these, due to its oligo-miocene age and because it is known from abundant material, is emuarius gidju. here, we describe additional material and confirm that the taxon h ... | 2014 | 24673760 |
bioactive magnetic nanoparticles of fe-ga synthesized by sol-gel for their potential use in hyperthermia treatment. | hyperthermia is one of the most recents therapies for cancer treatment using particles with nanometric size and appropriate magnetic properties for destroying cancer cells. magnetic nanoparticles (mnp's) of fe-ga and synthesized using a polycondensation reaction by sol-gel method were obtained. mnp's of fe(1.4)ga(1.6)o(4) that possess an inverse spinel structure were identified by x-ray diffraction, transmission electron microscopy, scanning electron microscopy and energy dispersive spectroscopy ... | 2014 | 24671332 |
tumor-derived inducible heat-shock protein 70 (hsp70) is an essential component of anti-tumor immunity. | the anti-apoptotic function and tumor-associated expression of heat-shock protein 70 (hsp70) is consistent with hsp70 functioning as a survival factor to promote tumorigenesis. however, its immunomodulatory activities to induce anti-tumor immunity predict the suppression of tumor growth. using the hsp70.1/3(-/-)(hsp70(-/-)) mouse model, we observed that tumor-derived hsp70 was neither required for cellular transformation nor for in vivo tumor growth. hsp70(-/-) murine embryonic fibroblasts (mefs ... | 2015 | 24662819 |
covalent immobilization of porcine pancreatic lipase on carboxyl-activated magnetic nanoparticles: characterization and application for enzymatic inhibition assays. | using carboxyl functionalized silica-coated magnetic nanoparticles (mnps) as carrier, a novel immobilized porcine pancreatic lipase (ppl) was prepared through the 1-ethyl-3-[3-dimethylaminopropyl] carbodiimide hydrochloride/n-hydroxysuccinimide (edc/nhs) coupling reaction. transmission electron microscopic images showed that the synthesized nanoparticles (fe3o4-sio2) possessed three dimensional core-shell structures with an average diameter of ~20 nm. the effective enzyme immobilization onto the ... | 2014 | 24656379 |
angiocrine factors deployed by tumor vascular niche induce b cell lymphoma invasiveness and chemoresistance. | tumor endothelial cells (ecs) promote cancer progression in ways beyond their role as conduits supporting metabolism. however, it is unknown how vascular niche-derived paracrine factors, defined as angiocrine factors, provoke tumor aggressiveness. here, we show that fgf4 produced by b cell lymphoma cells (lcs) through activating fgfr1 upregulates the notch ligand jagged1 (jag1) on neighboring ecs. in turn, upregulation of jag1 on ecs reciprocally induces notch2-hey1 in lcs. this crosstalk enforc ... | 2014 | 24651014 |
a case of psychogenic dizziness mimicking vestibular epilepsy. | a 28-year-old patient presented with frequent episodes of clockwise whirling vertigo, with no ear symptoms or anxiety. he had a previous history of encephaloduroarteriosynangiosis from moyamoya disease 3 years ago. we assumed that the ictus was a manifestation of vestibular epilepsy. although the patient was monitored continuously with video and computerized electroencephalography equipment for 24 hours, his vertigo was not accompanied by electroencephalographic discharges. and thorough vestibul ... | 2012 | 24649463 |
tuning of structural, optical, and magnetic properties of ultrathin and thin zno nanowire arrays for nano device applications. | one-dimensional (1-d) ultrathin (15 nm) and thin (100 nm) aligned 1-d (0001) and (0001¯) oriented zinc oxide (zno) nanowire (nw) arrays were fabricated on copper substrates by one-step electrochemical deposition inside the pores of polycarbonate membranes. the aspect ratio dependence of the compressive stress because of the lattice mismatch between nw array/substrate interface and crystallite size variations is investigated. x-ray diffraction results show that the polycrystalline zno nws have a ... | 2014 | 24636275 |
fe doped cdtes magnetic quantum dots for bioimaging. | a facile synthesis of 3-6 nm, water dispersible, near-infrared (nir) emitting, quantum dots (qds) magnetically doped with fe is presented. doping of alloyed cdtes nanocrystals with fe was achieved in situ using a simple hydrothermal method. the magnetic quantum dots (mqds) were capped with nacetyl-cysteine (nac) ligands, containing thiol and carboxylic acid functional groups to provide stable aqueous dispersion. the optical and magnetic properties of the fe doped mqds were characterized using se ... | 2013 | 24634776 |
structure and magnetism of the a site scandium perovskite (sc0.94mn0.06)mn0.65ni0.35o3 synthesized at high pressure. | scandium perovskite (sc0.94mn0.06)mn0.65ni0.35o3, synthesized at high pressure and high temperature, has a triclinic structure (space group ) at room temperature and ambient pressure with a √2ap×√2ap×2ap structure with α≈90(°),β≈89(°),γ≈90(°). magnetic measurements show that the material displays curie-weiss behaviour above 50 k with c=2.11 emu k mol(-1) (μeff=4.11 μb per formula unit) and θ=-95.27 k. bond valence sum analysis of the crystal structure shows that manganese is present in three dif ... | 2014 | 24615150 |
cdk4 deficiency promotes genomic instability and enhances myc-driven lymphomagenesis. | the g1 kinase cdk4 is amplified or overexpressed in some human tumors and promotes tumorigenesis by inhibiting known tumor suppressors. here, we report that cdk4 deficiency markedly accelerated lymphoma development in the eμ-myc transgenic mouse model of b lymphoma and that silencing or loss of cdk4 augmented the tumorigenic potential of myc-driven mouse and human b cell lymphoma in transplant models. accelerated disease in cdk4-deficient eμ-myc transgenic mice was associated with rampant genomi ... | 2014 | 24614102 |
a new model of lmp1-myc interaction in b cell lymphoma. | epstein-barr virus (ebv) is associated with aggressive b cell lymphomas (bcls). latent membrane protein 1 (lmp1) of ebv is an oncogenic protein required for ebv b cell transformation. however, lmp1 is a weak oncogene in mice. mice expressing myc inserted 5' of the eμ enhancer (imyc(eμ)), mimicking the t(8;14) translocation of endemic burkitt lymphoma, develop delayed onset bcls. to investigate potential cooperation between lmp1 and oncogenic myc, we produced mice expressing the lmp1 signaling do ... | 2014 | 24605938 |
oleylamine as a beneficial agent for the synthesis of cofe₂o₄ nanoparticles with potential biomedical uses. | the multifunctional role of oleylamine (oam) as a versatile and flexible reagent in synthesis as well as a desired surface ligand for the synthesis of cofe2o4 nanoparticles (nps) is described. cofe2o4 nps were prepared by a facile, reproducible and scalable solvothermal approach in the presence of pure oam. by monitoring the volume of oam, different shapes of nps, spherical and truncated, were formed. the syntheses led to high yields of monodispersed and considerably small (9-11 nm) cofe2o4 nps ... | 2014 | 24604256 |
fabrication of multifunctional layer-by-layer nanocapsules toward the design of theragnostic nanoplatform. | self-assembled polymeric nanocapsules (ncs) that incorporate dendrimer porphyrin (dp) in the shells and superparamagnetic iron oxide nanoparticles (spions) in the cores are fabricated to create a theragnostic platform for the application in photodynamic therapy (pdt) and magnetic resonance imaging (mri). spions-embedded polystyrene nps (spions@ps) are used as a template to build up multilayered ncs. the formation of pah/dp multilayer on the spions@ps is monitored by zeta-pential and fluorescence ... | 2014 | 24598017 |
fabrication and magnetic properties of nickel dodecahedra. | here we report a one-pot route for the synthesis of nickel dodecahedra with 52.3 ± 0.1 emu g(-1) of saturation magnetization. the procedure is very simple, and only three chemicals (nicl2·6h2o, isopropanol and polyvinylpyrrolidone) are used throughout the entire synthetic process. during the reaction, it is believed that the application of isopropanol and the amount of polyvinylpyrrolidone play an essential role in forming the dodecahedral morphology of the final product. furthermore, a formatio ... | 2014 | 24590297 |
rae1 ligands for the nkg2d receptor are regulated by sting-dependent dna sensor pathways in lymphoma. | the immunoreceptor nkg2d originally identified in natural killer (nk) cells recognizes ligands that are upregulated on tumor cells. expression of nkg2d ligands (nkg2dl) is induced by the dna damage response (ddr), which is often activated constitutively in cancer cells, revealing them to nk cells as a mechanism of immunosurveillance. here, we report that the induction of retinoic acid early transcript 1 (rae1) ligands for nkg2d by the ddr relies on a sting-dependent dna sensor pathway involving ... | 2014 | 24590060 |
a re-evaluation of sperm ultrastructure in the emu, dromaius novaehollandiae. | existing reports on sperm structure in the emu do not adequately illustrate or describe all the salient ultrastructural features necessary for a meaningful comparison of normal and abnormal sperm in this species. as sperm morphology forms an important parameter in determining semen quality, and in view of the proposed role of artificial insemination in the farming of ratites, this article re-evaluates and complements the existing data on the topic, provides a fully illustrated description of emu ... | 2014 | 24581588 |
ctcf and ncrna regulate the three-dimensional structure of antigen receptor loci to facilitate v(d)j recombination. | at both the immunoglobulin heavy and kappa light chain loci, there are >100 functional variable (v) genes spread over >2 mb that must move into close proximity in 3d space to the (d)j genes to create a diverse repertoire of antibodies. similar events take place at the t cell receptor (tcr) loci to create a wide repertoire of tcrs. in this review, we will discuss the role of ctcf in forming rosette-like structures at the antigen receptor (agr) loci, and the varied roles it plays in alternately fa ... | 2014 | 24575097 |
a modified nonlinear damage accumulation model for fatigue life prediction considering load interaction effects. | many structures are subjected to variable amplitude loading in engineering practice. the foundation of fatigue life prediction under variable amplitude loading is how to deal with the fatigue damage accumulation. a nonlinear fatigue damage accumulation model to consider the effects of load sequences was proposed in earlier literature, but the model cannot consider the load interaction effects, and sometimes it makes a major error. a modified nonlinear damage accumulation model is proposed in thi ... | 2014 | 24574866 |
epigenetics as a source of variation in comparative animal physiology - or - lamarck is lookin' pretty good these days. | considerable variation is inherent both within and between comparative physiological data sets. known sources for such variation include diet, gender, time of day and season of experiment, among many other factors, but a meta-analysis of physiological studies shows that surprisingly few studies report controlling for these factors. in fact, less than 3% of comparative physiological papers mention epigenetics. however, our understanding of epigenetic influences on physiological processes is growi ... | 2014 | 24574384 |
transportation stress and the incidence of exertional rhabdomyolysis in emus (dromaius novaehollandiae). | many emu farms are located in areas lacking processing facilities that can handle these birds. thus, long-distance shipping of birds to an abattoir is necessary. two experiments were conducted, wherein emus were transported in a modified horse trailer for 6 h to an abattoir. changes in the indices of stress and metabolic homeostasis (hematology, serum biochemistry, enzymes, and body temperature and weight) were used to evaluate the physiological response to transport. the activities of enzymes a ... | 2014 | 24570448 |
synthesis and characterization of zinc and calcium nanoferrites. | in this work, zn(1-x)caxfe(2)o(4) nanoparticles (x = 0, 0.5 and 1) have been synthesized by sol-gel method followed by heat treatment at a temperature within the range of 300-700 °c. the samples with appropriate saturation magnetization (ms), low coercivity and remanence were zn(0)ca(1)fe(2)o(4) treated at 300 °c (ms ~ 25 emu/g), zn(0)ca(1)fe(2)o(4) treated at 400 °c (ms ~ 40 emu/g) and zn(0.50)ca(0.50)fe(2)o(4) treated at 400 °c (ms ~ 31 emu/g). these samples were analyzed by scanning electron ... | 2014 | 24570349 |
quality indicators in an epilepsy monitoring unit. | examining and improving the quality of care in epilepsy monitoring units (emus) is essential to delivering the best possible care and to mitigating undesirable outcomes. epilepsy monitoring units are unique in that an admission to an emu often involves the induction of symptoms (seizures) rather than minimizing and/or treating symptoms, which can lead to an increased risk to patient safety. very little research has addressed the quality of care and safety in emus. the objective of this study was ... | 2014 | 24561652 |
a new magnetic expanded graphite for removal of oil leakage. | magnetic expanded graphite (meg) was prepared using the blended calcination method under a nitrogen atmosphere. meg was characterized by scanning electron microscope (sem), x-ray powder diffraction (xrd), raman spectroscopy, and vibrating sample magnetization (vsm). results show that the cobalt ferrite nanoparticles were uniformly and efficiently deposited on expanded graphite (eg). the saturation magnetization reached 55.05 emu g(-1), and the adsorption capacity of meg under the optimal conditi ... | 2014 | 24559739 |
patients' safety in the epilepsy monitoring unit: time for revising practices. | long-term video-electroencephalography monitoring (ltm) in epilepsy monitoring units (emus) exposes patients to a variety of serious adverse events (saes) and safety issues, which have recently caught attention and are summarized in this review. | 2014 | 24553465 |
adsorption of c.i. reactive red 228 and congo red dye from aqueous solution by amino-functionalized fe3o4 particles: kinetics, equilibrium, and thermodynamics. | a magnetic adsorbent was synthesized by γ-aminopropyltriethoxysilane (aptes) modification of fe(3)o(4) particles using a two-step process. scanning electron microscopy (sem), energy-dispersive x-ray spectroscopy (eds), x-ray photoelectron spectroscopy (xps), and vibration sample magnetometry were used to characterize the obtained magnetic adsorbent. eds and xps showed that aptes polymer was successfully introduced onto the as-prepared fe(3)o(4)/aptes particle surfaces. the saturation magnetizati ... | 2014 | 24552735 |
fabrication and neuron cytocompatibility of iron oxide nanoparticles coated with silk-fibroin peptides. | neuro-cytotoxicity of iron oxide nanoparticles (nps) need to be considered. in this paper, magnetic fe3o4 nps are synthesized via a bio-mineralization process using silk fibroin (sf) as template. the prepared nps with sf (sf-nps) have more uniform grain size, better stability in weakly alkaline solution and higher saturation magnetization (about 82 emu/g) than pure nps. after exposure to different concentration of sf-nps (6.25-100 μg/ml), the reactive oxygen species generation in pc12 cells redu ... | 2014 | 24552663 |
a novel thermal reduction method towards the synthesis and growth of two unlike morphologies of nickel nanostructures. | a facile method is described for synthesizing quasi-cotton fiber and spherical nickel nanostructures via a thermal reduction of ni(acac)2 (acac = acetylacetonate) in n,n-dimethylformamide (dmf) and in the presence and absence of sodium thiosulfate, respectively. xps analysis revealed the existence of ni(2+) and so4(2-) ions on the surface of nickel nanostructures obtained in the presence of anhydrous sodium thiosulfate. magnetic measurements of this sample resulted in lower values of saturation ... | 2014 | 24531499 |
2013 early career achievement award--proteomics of muscle- and species-specificity in meat color stability. | meat color is the most important quality trait influencing consumer purchase decisions. the interinfluential interactions between myoglobin and biomolecules govern color stability in meat. the advances in proteomics, such as high throughput analytical tools in mass spectrometry, 2-dimensional electrophoresis, and bioinformatics, offer themselves as robust techniques to characterize the proteome basis of muscle- and species-specific meat color phenomena. differential abundance of chaperones and a ... | 2014 | 24496833 |
hollow superparamagnetic plga/fe3o4 composite microspheres for lysozyme adsorption. | uniform hollow superparamagnetic poly(lactic-co-glycolic acid) (plga)/fe(3)o(4) composite microspheres composed of an inner cavity, plga inner shell and fe(3)o(4) outer shell have been synthesized by a modified oil-in-water (o/w) emulsion-solvent evaporation method using fe(3)o(4) nanoparticles as a particulate emulsifier. the obtained composite microspheres with an average diameter of 2.5 μm showed excellent monodispersity and stability in aqueous medium, strong magnetic responsiveness, high ma ... | 2014 | 24492410 |
effects of surfactants on the magnetic properties of iron oxide colloids. | iron oxide nanoparticles are having been extensively investigated for several biomedical applications such as hyperthermia and magnetic resonance imaging. however, one of the biggest problems of these nanoparticles is their aggregation. taking this into account, in this study the influence of three different surfactants (oleic acid, sodium citrate and triton x-100) each one with various concentrations in the colloidal solutions stability was analyzed by using a rapid and facile method, the varia ... | 2014 | 24491328 |
large-scale synthesis of monodisperse magnesium ferrite via an environmentally friendly molten salt route. | sub-micrometer-sized magnesium ferrite spheres consisting of uniform small particles have been prepared using a facile, large-scale solid-state reaction employing a molten salt technique. extensive structural characterization of the as-prepared samples has been performed using scanning electron microscope, transmission electron microscopy, high-resolution transmission electron microscopy, selected area electron diffraction, and x-ray diffraction. the yield of the magnesium ferrite sub-micrometer ... | 2014 | 24483938 |
preparation of monodisperse ferrite nanocrystals with tunable morphology and magnetic properties. | the synthesis of monodisperse magnetic ferrite nanomaterials plays an important role in several scientific and technological areas. in this work, dibasic spinel mfe2o4 (m=mg, ni, co, fe, mn) and polybasic spinel ferrite mcofeo4 (m=mg, ni, mn, mgni) nanocrystals were prepared by the calcination of layered double hydroxide (ldh) precursors at 900 °c, which was confirmed by x-ray diffraction (xrd) and fourier transform infrared (ftir) spectroscopy. scanning electron microscopy (sem) and transmissio ... | 2014 | 24482379 |
iodine-enhanced micro-ct imaging: methodological refinements for the study of the soft-tissue anatomy of post-embryonic vertebrates. | the now widespread use of non-destructive x-ray computed tomography (ct) and micro-ct (µct) has greatly augmented our ability to comprehensively detail and quantify the internal hard-tissue anatomy of vertebrates. however, the utility of x-ray imaging for gaining similar insights into vertebrate soft-tissue anatomy has yet to be fully realized due to the naturally low x-ray absorption of non-mineralized tissues. in this study, we show how a wide diversity of soft-tissue structures within the ver ... | 2014 | 24482316 |
thermal stability of mnbi magnetic materials. | mnbi has attracted much attention in recent years due to its potential as a rare-earth-free permanent magnet material. it is unique because its coercivity increases with increasing temperature, which makes it a good hard phase material for exchange coupling nanocomposite magnets. mnbi phase is difficult to obtain, partly because the reaction between mn and bi is peritectic, and partly because mn reacts readily with oxygen. mno formation is irreversible and harmful to magnet performance. in this ... | 2014 | 24469323 |
fe-ni composition dependence of magnetic anisotropy in artificially fabricated l1 0-ordered feni films. | we prepared l10-ordered feni alloy films by alternate deposition of fe and ni monatomic layers, and investigated their magnetic anisotropy. we employed a non-ferromagnetic au-cu-ni buffer layer with a flat surface and good lattice matching to l10-feni. an l10-feni film grown on au6cu51ni43 showed a large uniaxial magnetic anisotropy energy (ku = 7.0 × 10(6) erg cm(-)3). ku monotonically increased with the long-range order parameter (s) of the l10 phase. we investigated the fe-ni composition depe ... | 2014 | 24469082 |
a comparison of τ-mnal particulates produced via different routes. | mnal alloys are very promising rare-earth-free permanent magnets. nanocrystalline microstructures can have beneficial effects on the properties of magnetic mnal alloys. in the present work we examined multiple routes to process mnal alloys and studied the effects of milling on mn-46 at.% al powders. mn54al46 was produced via gas atomization, melt spinning, and rapid solidification rate processing. it was then mechanically milled using a water-cooled union process attritor for times up to 20 h. x ... | 2014 | 24468799 |
novel kojic acid-polymer-based magnetic nanocomposites for medical applications. | iron oxide magnetic nanoparticles (mnps) were synthesized by the coprecipitation of iron salts in sodium hydroxide followed by coating separately with chitosan (cs) and polyethylene glycol (peg) to form cs-mnps and peg-mnps nanoparticles, respectively. they were then loaded with kojic acid (ka), a pharmacologically bioactive natural compound, to form ka-cs-mnps and ka-peg-mnps nanocomposites, respectively. the mnps and their nanocomposites were characterized using powder x-ray diffraction, fouri ... | 2014 | 24453486 |
brief group psychoeducation for psychogenic nonepileptic seizures: a neurologist-initiated program in an epilepsy center. | to evaluate therapeutic efficacy upon augmenting the initial communication to patients regarding the diagnosis of psychogenic nonepileptic seizures (pnes) with a novel, brief group psychoeducation administered by the same team that provided the video-electroencephalography (veeg) confirmed diagnosis and within 4 weeks of the diagnosis. | 2014 | 24446955 |
flt3 signaling regulates the proliferation, survival, and maintenance of multipotent hematopoietic progenitors that generate b cell precursors. | flt3 signaling plays a crucial role in regulating the survival and differentiation of lymphoid progenitors into b cell precursors (bcps) in bone marrow. to define further the role of flt3 signaling in lymphoid progenitor survival, mice deficient in flt3 ligand that also expressed a bcl2 transgene (eμ-bcl2tg flt3l(-/-)) were generated. intracellular flow cytometry established transgene expression in primitive hematopoietic progenitors, including lineage-negative sca-1(+) c-kit(+) (lsk(+)) cd27(-) ... | 2014 | 24444745 |
magnetic fe3o4@c nanoparticles as adsorbents for removal of amoxicillin from aqueous solution. | in the present study, powder activated carbon (pac) combined with fe(3)o(4) magnetite nanoparticles (mnps) were used for the preparation of magnetic composites (mnps-pac), which was used as an adsorbent for amoxicillin (amx) removal. the properties of magnetic activated carbon were characterized by scanning electron microscopy, transmission electron microscopy, x-ray diffraction, brunaeur, emmett and teller and vibrating sample magnetometer. the operational factors affecting adsorption such as p ... | 2014 | 24434981 |
an interface-directed coassembly approach to synthesize uniform large-pore mesoporous silica spheres. | a facile and controllable interface-directed coassembly (idca) approach is developed for the first time to synthesize uniform discrete mesoporous silica particles with a large pore size (ca. 8 nm) by using 3-dimensional macroporous carbon (3domc) as the nanoreactor for the confined coassembly of template molecules and silica source. by controlling the amount of the precursor solution and using pluronic templates with different compositions, we can synthesize mesoporous silica particles with dive ... | 2014 | 24417352 |
evaluation of nickel ferrite nanoparticles coated with oleylamine by nmr relaxation measurements and magnetic hyperthermia. | nickel ferrite nanoparticles were synthesized via a facile solvothermal approach. oleylamine (oam) was used in all synthetic procedures as a stabilizing agent and solvent. by varying the polarity of the solvents, hydrophobic nife2o4 nanoparticles coated with oam of relatively similar sizes (9-11.7 nm) and in a range of magnetization values (32.0-53.5 emu g(-1)) were obtained. the as-prepared hydrophobic nanoparticles were characterized by xrd, tem, sem, tga and vsm and converted to hydrophilic b ... | 2014 | 24413465 |
using body temperature, food and water consumption as biomarkers of disease progression in mice with eμ-myc lymphoma. | non-invasive biomarkers of disease progression in mice with cancer are lacking making it challenging to implement appropriate humane end points. we investigated whether body temperature, food and water consumption could be used to predict tumour burden. | 2014 | 24407190 |
preparation of a novel magnetic microporous adsorbent and its adsorption behavior of p-nitrophenol and chlorotetracycline. | a novel method for fabricating hypercrosslinked magnetic polymer beads with improved acid resistance was developed. magnetite nanoparticles were covered with tetraethoxysilane and vinyltriethoxysilane, followed by co-polymerization and post-crosslinking. the resulting m150 beads were highly stable at ph ≥ 2 and were superparamagnetic, with a saturation magnetization of 3.1 emu/g. m150 exhibited a specific surface area of 1022.4m(2)/g and an average pore width of 2.6 nm. the adsorption of p-nitro ... | 2014 | 24380891 |
ror1 can interact with tcl1 and enhance leukemogenesis in eμ-tcl1 transgenic mice. | receptor tyrosine kinase-like orphan receptor 1 (ror1) is an oncoembryonic antigen found on chronic lymphocytic leukemia (cll) b cells, but not on normal adult tissues. we generated transgenic (tg) mice with human ror1 regulated by the murine ig promoter/enhancer. in contrast to nontransgenic littermates, such animals had b-cell-restricted expression of ror1 and could develop clonal expansions of ror1(bright)cd5(+)b220(low) b cells resembling human cll at ≥ 15 mo of age. because immune-precipita ... | 2014 | 24379361 |
surface modification and bioconjugation of feco magnetic nanoparticles with proteins. | magnetic fe70co30 nanoparticles with a cubic shape and a mean size of 15±1.5 nm were fabricated using a magnetron-sputtering-based gas phase condensation deposition method. the particles had a high saturation magnetization of 220 emu/g, which is much higher than that of commercially available iron oxide nanoparticles. the feco nanoparticles were modified by 3-aminopropyltriethoxy silane and subsequently activated by glutaraldehyde, leading to successful attachment of aldehyde groups onto nanopar ... | 2014 | 24373979 |
sirt4 protein suppresses tumor formation in genetic models of myc-induced b cell lymphoma. | glutamine metabolism plays an essential role for growth and proliferation of many cancer cells by providing metabolites for the maintenance of mitochondrial functions and macromolecular synthesis. aberrant activation of the transcription factor c-myc, e.g. caused by t(8;14) chromosomal translocation commonly found in burkitt lymphoma, is a key driver of cellular glutamine metabolism in many tumors, highlighting the need to identify molecular mechanisms that can suppress glutamine usage in these ... | 2014 | 24368766 |
zebrafish etv7 regulates red blood cell development through the cholesterol synthesis pathway. | etv7 is a human oncoprotein that cooperates with eμ-myc to promote pre-b-cell leukemia in mice. it is normally expressed in the bone marrow and fetal liver and is upregulated in primary leukemia, suggesting that it is involved in proper hematopoiesis and leukemogenesis. etv7 has been deleted in most rodents, but is conserved in all other vertebrates, including the zebrafish, danio rerio. in this report, we characterize the function of the zebrafish etv7 gene during erythropoiesis. our results de ... | 2014 | 24357328 |
single domain smco5@co exchange-coupled magnets prepared from core/shell sm[co(cn)6]·4h2o@go particles: a novel chemical approach. | smco5 based magnets with smaller size and larger maximum energy product have been long desired in various fields such as renewable energy technology, electronic industry and aerospace science. however, conventional relatively rough synthetic strategies will lead to either diminished magnetic properties or irregular morphology, which hindered their wide applications. in this article, we present a facile chemical approach to prepare 200 nm single domain smco5@co core/shell magnets with coercivity ... | 2013 | 24356309 |
removal of pcp-na from aqueous systems using monodispersed pompon-like magnetic nanoparticles as adsorbents. | novel monodispersed pompon-like magnetite/chitosan (fe3o4/cs) composite nanoparticles were synthesized by a solvothermal method and used as adsorbents for the removal of toxic sodium pentachlorophenate (pcp-na) from aqueous media. the adsorption behavior of pcp-na on fe3o4/cs obeyed the langmuir isotherm and fitted the pseudo-second-order kinetics model. thermodynamic parameters showed that the adsorption process was exothermic and spontaneous. moreover, the adsorption was strongly ph-dependent. ... | 2013 | 24355861 |
mantle cell lymphoma in cyclin d1 transgenic mice with bim-deficient b cells. | mantle cell lymphoma (mcl) is a highly aggressive b-cell lymphoma resistant to conventional chemotherapy. although defined by the characteristic t(11;14) translocation, mcl has not been recapitulated in transgenic mouse models of cyclin d1 overexpression alone. indeed, several genetic aberrations have been identified in mcl that may contribute to its pathogenesis and chemoresistance. of particular interest is the frequent biallelic deletion of the proapoptotic bcl-2 family protein bim. bim exert ... | 2014 | 24352880 |
self-ignited high temperature synthesis and enhanced super-exchange interactions of ho(3+)-mn(2+)-fe(3+)-o(2-) ferromagnetic nanoparticles. | the present work is focused on the effect of fe(3+) replacement by rare earth-ho(3+) ions and their influence on the properties of mnfe2o4 ferrite. the ho(3+) substituted mnfe2o4 ferrite samples with chemical formula mnhoxfe2-xo4 were synthesized where substitution concentration of ho(3+) was 0.0, 0.05, 0.1 and 0.15. the samples were synthesized by the self-ignited sol-gel method using the nitrates of the respective elements. powder x-ray diffraction, transmission electron microscopy, infrared s ... | 2014 | 24352649 |
preparation of soft magnetic fe-ni-pb-b alloy nanoparticles by room temperature solid-solid reaction. | the fe-ni-pb-b alloy nanoparticles was prepared by a solid-solid chemical reaction of ferric trichloride, nickel chloride, lead acetate, and potassium borohydride powders at room temperature. the research results of the icp and thermal analysis indicate that the resultants are composed of iron, nickel, lead, boron, and pvp, and the component of the alloy is connected with the mole ratio of potassium borohydride and the metal salts. the tem images show that the resultants are ultrafine and spheri ... | 2013 | 24348196 |
ultrasound-assisted fabrication of a biocompatible magnetic hydroxyapatite. | this work describes the fabrication and characterization of a biocompatible magnetic hydroxyapatite (ha) using an ultrasound-assisted co-precipitation method. x-ray diffraction (xrd), fourier transform infrared spectroscopy (ft-ir), and transmission electron microscopy (tem) were used to characterize the structure and chemical composition of the produced samples. the m-h loops of synthesized materials were traced using a vibrating sample magnetometer (vsm) and the biocompatibility was evaluated ... | 2014 | 24339231 |
an efficient magnetically modified microbial cell biocomposite for carbazole biodegradation. | magnetic modification of microbial cells enables to prepare smart biocomposites in bioremediation. in this study, we constructed an efficient biocomposite by assembling fe3o4 nanoparticles onto the surface of sphingomonas sp. xldn2-5 cells. the average particle size of fe3o4 nanoparticles was about 20 nm with 45.5 emu g-1 saturation magnetization. the morphology of sphingomonas sp. xldn2-5 cells before and after fe3o4 nanoparticle loading was verified by scanning electron microscopy and transmis ... | 2013 | 24330511 |
the double bromodomain protein brd2 promotes b cell expansion and mitogenesis. | bromodomain-containing transcriptional regulators represent new epigenetic targets in different hematologic malignancies. however, bromodomain-mediated mechanisms that couple histone acetylation to transcription in lymphopoiesis and govern mature lymphocyte mitogenesis are poorly understood. brd2, a transcriptional coregulator that contains dual bromodomains and an extraterminal domain (the bet family), couples chromatin to cell-cycle progression. we reported previously the first functional char ... | 2014 | 24319289 |
bruton's tyrosine kinase (btk) function is important to the development and expansion of chronic lymphocytic leukemia (cll). | chronic lymphocytic leukemia (cll) is characterized by constitutive activation of the b-cell receptor (bcr) signaling pathway, but variable responsiveness of the bcr to antigen ligation. bruton's tyrosine kinase (btk) shows constitutive activity in cll and is the target of irreversible inhibition by ibrutinib, an orally bioavailable kinase inhibitor that has shown outstanding activity in cll. early clinical results in cll with other reversible and irreversible btk inhibitors have been less promi ... | 2014 | 24311722 |
repurposing crispr/cas9 for in situ functional assays. | rnai combined with next-generation sequencing has proven to be a powerful and cost-effective genetic screening platform in mammalian cells. still, this technology has its limitations and is incompatible with in situ mutagenesis screens on a genome-wide scale. using p53 as a proof-of-principle target, we readapted the crispr (clustered regularly interspaced short palindromic repeats)/cas9 (crispr associated 9) genome-editing system to demonstrate the feasibility of this methodology for targeted g ... | 2013 | 24298059 |
the neuromodulator of exploration: a unifying theory of the role of dopamine in personality. | the neuromodulator dopamine is centrally involved in reward, approach behavior, exploration, and various aspects of cognition. variations in dopaminergic function appear to be associated with variations in personality, but exactly which traits are influenced by dopamine remains an open question. this paper proposes a theory of the role of dopamine in personality that organizes and explains the diversity of findings, utilizing the division of the dopaminergic system into value coding and salience ... | 2013 | 24294198 |
the role of p21(waf1/cip1) and p27(kip1) in hdaci-mediated tumor cell death and cell cycle arrest in the eμ-myc model of b-cell lymphoma. | following the establishment of histone deacetylases (hdacs) as promising therapeutic targets for the reversal of aberrant epigenetic states associated with cancer, the development of hdac inhibitors (hdaci) and their underlying mechanisms of action has been a significant area of scientific interest. hdaci induce diverse biological responses including the inhibition of cell proliferation by blocking progression through the g1 or g2/m phases of the cell cycle. as a putative tumor-suppressor protei ... | 2014 | 24292681 |
large pore mesostructured cellular silica foam coated magnetic oxide composites with multilamellar vesicle shells for adsorption. | herein, large pore mesostructured cellular silica foam coated magnetic oxide composites (mo@mcfs) with multilamellar vesicle shells (mo@mlvs) were obtained, which exhibited a large pore (>10 nm), strong magnetic response (38 emu g(-1)), excellent protein adsorption and slow drug-release capacity. | 2014 | 24287967 |
enhanced luminescence of camoo₄:eu by core@shell formation and its hyperthermia study after hybrid formation with fe₃o₄: cytotoxicity assessment on human liver cancer cells and mesenchymal stem cells. | highly water dispersible eu³⁺ doped camoo₄ nanoparticles (core) covered by camoo₄ (shell) have been prepared using the polyol method. significant enhancement in luminescence intensity by core@shell formation is observed due to the decrease of non-radiative rate arising from surface/defect of particles. effect of 266 nm laser excitation (mo-o charge transfer band) on the asymmetric ratio (a₂₁ = intensity ratio of electric to magnetic dipole transitions) has been studied and compared with a xenon ... | 2014 | 24287920 |
blocking lactate export by inhibiting the myc target mct1 disables glycolysis and glutathione synthesis. | myc oncoproteins induce genes driving aerobic glycolysis, including lactate dehydrogenase-a that generates lactate. here, we report that myc controls transcription of the lactate transporter slc16a1/mct1 and that elevated mct1 levels are manifest in premalignant and neoplastic eμ-myc transgenic b cells and in human malignancies with myc or mycn involvement. notably, disrupting mct1 function leads to an accumulation of intracellular lactate that rapidly disables tumor cell growth and glycolysis, ... | 2014 | 24285728 |
a facile method for preparing porous, optically active, magnetic fe3 o4 @poly(n-acryloyl-leucine) inverse core/shell composite microspheres. | the first synthesis of porous, optically active, magnetic fe3 o4 @poly(n-acryloyl-leucine) inverse core/shell composite microspheres is reported, in which the core is constructed of chiral polymer and the shell is constructed of fe3 o4 nps. the microspheres integrate three significant concepts, "porosity", "chirality", and "magneticity", in one single microspheric entity. the microspheres consist of fe3 o4 nanoparticles and porous optically active microspheres, and thus combine the advantages of ... | 2014 | 24285562 |
synthesis and microwave absorption properties of electromagnetic functionalized fe3o4-polyaniline hollow sphere nanocomposites produced by electrostatic self-assembly. | highly regulated fe3o4-polyelectrolyte-modified polyaniline (fe3o4-pe@pani) hollow sphere nanocomposites were successfully synthesized using an electrostatic self-assembly approach. the morphology and structure of the fe3o4-pe@pani nanocomposites were characterized using field-emission scanning electron microscopy, transmission electron microscopy, fourier-transform infrared spectroscopy, x-ray powder diffraction, thermogravimetric analysis, and x-ray photoelectron spectroscopy. the results show ... | 2013 | 24273439 |
nickel nanoparticle decorated graphene for highly selective isolation of polyhistidine-tagged proteins. | nickel nanoparticle decorated graphene (gp-ni) is prepared by one-pot hydrothermal reduction of graphene oxide and nickel cations by hydrazine hydrate in the presence of poly(sodium-p-styrenesulfonate) (pss). the gp-ni hybrid is characterized by xrd, tem, sem, xps, raman and ft-ir spectra, demonstrating the formation of poly-dispersed nickel nanoparticles with an average size of 83 nm attached on the surface of graphene sheets. the gp-ni hybrid exhibits ferromagnetic behavior with a magnetizatio ... | 2013 | 24270901 |
variations in magnetic properties of nanostructured nickel. | the magnetic properties of carbon nanotube encapsulated nickel nanowires (c.e. nanowires of diameter to approximately 10 nm), and its comparison to other forms of ni are carried out in this work. the saturation magnetization (ms) and coercivity (hc) for c.e. nanowires are 1.0 emu/g and 230 oe. the temperature dependence of coercivity follows t0.77 dependence indicating a superparamagnetic behavior. the field-cooled and zero-field-cooled plots indicate that the blocking temperature (t(b)) to appr ... | 2013 | 24266209 |
evolution of a developmental mechanism: species-specific regulation of the cell cycle and the timing of events during craniofacial osteogenesis. | neural crest mesenchyme (ncm) controls species-specific pattern in the craniofacial skeleton but how this cell population accomplishes such a complex task remains unclear. to elucidate mechanisms through which ncm directs skeletal development and evolution, we made chimeras from quail and duck embryos, which differ markedly in their craniofacial morphology and maturation rates. we show that quail ncm, when transplanted into duck, maintains its faster timetable for development and autonomously ex ... | 2014 | 24262986 |
weak ferromagnetic ordering of the li(+)[tcne](•-) (tcne = tetracyanoethylene) organic magnet with an interpenetrating diamondoid structure. | li[tcne] (tcne = tetracyanoethylene) magnetically orders as a weak ferromagnet (canted antiferromagnet) below 21.0 ± 0.1 k, as observed from the bifurcation of the field-cooled and zero-field-cooled magnetizations, as well as remnant magnetization. the structure, determined ab initio from synchrotron x-ray powder diffraction data, consists of a planar μ4-[tcne](•-) bound to four tetrahedral li(+) ions. the structure consists of two interpenetrating diamondoid sublattices, with closest interlatti ... | 2013 | 24261863 |
diagnostic outcomes of inpatient video electroencephalography: nonepileptic events in south carolina. | the epilepsy monitoring unit (emu) was established at the medical university hospital to assist in the diagnosis of epilepsy and the evaluation of other paroxysmal neurological symptoms, including non-epileptic events (nees), which are often confused with epileptic seizures. correct diagnosis can prevent inappropriate treatment with antiepileptic drugs, avoid some of the restrictions imposed by epileptic seizures, and facilitate appropriate treatment for nees. a retrospective review of patients ... | 2013 | 24261154 |
antiferromagnetic iron nanocolloids: a new generation in vivo t1 mri contrast agent. | a novel t1 agent, antiferromagnetic α-iron oxide-hydroxide (α-feooh) nanocolloids with a diameter of 2-3 nm, has been successfully prepared. these nanocolloids, together with a post synthetic strategy performed in mesoporous silica, are a great improvement over the low t1-weighted contrast common in traditional magnetic silica nanocomposites. the intrinsic antiferromagnetic goethite (α-feooh) shows very low magnetization (m(z)) of 0.05 emu g(-1) at h = 2 t at 300 k (0.0006 emu g(-1) for feooh/wm ... | 2013 | 24256331 |
crystal structures of manganese and cobalt dichloride monohydrate and deuteration effects on magnetic behavior. | this work reports the long sought crystal structures of the title members of the intriguing series of 3d transition metal dichloride monohydrates. the double chain structure which results from rearrangement of the well-known pseudo-octahedral coordination geometry and single chains in the corresponding metal chloride dihydrate is extremely unusual. mncl2·h2o and cocl2·h2o each crystallize in orthorhombic space group pnma with z = 4 and lattice parameters a = 9.0339(1), 8.8207(3); b = 3.68751(5), ... | 2013 | 24251931 |
comparing the efficacy of emu oil with clotrimazole and hydrocortisone in the treatment of seborrheic dermatitis: a clinical trial. | seborrheic dermatitis (sd) is a common, chronic inflammatory disease. inflammatory reaction and oxidative stress are thought to be effective in the pathogenesis of sd. based on anti-inflammatory and anti-oxidant properties of emu oil, this study was designed to evaluate effects of emu oil on patients suffering from sd, and to compare it with routine treatments of sd with topical steroids and antifungal agents. | 2013 | 24250695 |
surface coated eu(oh)3 nanorods: a facile synthesis, characterization, mr relaxivities and in vitro cytotoxicity. | the water-soluble and biocompatible d-glucuronic acid coated eu(oh)3 nanorods (average thickness x average length = 9.0 x 118.3 nm) have been prepared in one-pot synthesis. the d-glucuronic acid coated eu(oh)3 nanorods showed a strong fluorescence at approximately 600 nm with a narrow emission band width. a cytotoxicity test by using du145 cells showed that d-glucuronic acid coated eu(oh)3 nanorods are not toxic up to 100 microm, making them a promising candidate for biomedical applications such ... | 2013 | 24245232 |
bulk synthesis of monodisperse magnetic feni3 nanopowders by flow levitation method. | in this work, a novel bulk synthesis method for monodisperse feni3 nanoparticles was developed by flow levitation method (fl). the fe and ni vapours ascending from the high temperature levitated droplet was condensed by cryogenic ar gas under atmospheric pressure. x-ray diffraction was used to identify and characterize the crystal phase of prepared powders exhibiting a feni3 phase. the morphology and size of nanopowders were observed by transmission electron microscopy (tem). the chemical compos ... | 2013 | 24245162 |