Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
|---|
| endoparasites of the coyote (canis latrans), a recent migrant to insular newfoundland. | this study provides the first data on the helminth fauna of the coyote (canis latrans) in insular newfoundland. sixty-nine coyotes were collected between 2001 and 2003 and examined for helminths. a total of 10 helminth species were recorded: the cestodes taenia ovis krabbei (9%), taenia hydatigena (4%), taenia pisiformis (1%), and mesocestoides spp. (5%); and the nematodes toxocara canis (19%), toxascaris leonina (1%), crenosoma vulpis (19%), physaloptera rara (6%), uncinaria stenocephala (3%), ... | 2009 | 19901402 |
| in vitro cytokine responses of peripheral blood mononuclear cells from healthy dogs to distemper virus, malassezia and toxocara. | naïve cd4+ t cells may differentiate into a number of subsets including t helper 1 (th1) th2, th3, th17 and t regulatory (treg) cells depending on the type of antigen they encounter. these cd4+ families have been defined based on the array of cytokines they produce and the effects they have on adaptive immune responses. cd4+ subsets are cross regulatory and at times cooperative. the study of these adaptive immune modulators has revealed the important role that cytokines play in mounting effectiv ... | 2010 | 19880197 |
| recovery threshold of toxocara canis eggs from soil. | the purpose of this study was to evaluate the threshold of toxocara canis eggs form soil samples through utilisation of a centrifuge-flotation technique (cft). aliquots of soil (1g each) were artificially contaminated with known numbers of t. canis eggs (1, 10, 25, 50, 100, and 200 eggs). the threshold was evaluated based on a cft using zinc sulphate (zn(2)so(4)) and sodium nitrate (na(2)no(3)) solutions at a specific gravity of 1.20. the number of eggs recovered was directly proportional to the ... | 2010 | 19879694 |
| a wide diversity of zoonotic intestinal parasites infects urban and rural dogs in neuquén, patagonia, argentina. | the presence of parasites was investigated by the examination of 1944 dog faecal samples collected from urban (n=646) and rural (n=1298) areas of the province of neuquén, patagonia, argentina. parasitic agents (pa) were found in 37.86% of samples. a total of 15 different pa were detected, including toxocara canis (16.35%), taenia spp./echinococcus spp. (12.65%), trichurisvulpis (6.06%), giardia spp. (1.29%), toxascaris leonina (0.56%), ancylostomacaninum (0.41%), dipylidium caninum (0.31%), diph ... | 2010 | 19864068 |
| toxocariasis: incidence, prevalence and the time serum remains positive in school children from campinas, sp, brazil. | 2010 | 19850711 | |
| immunohistochemistry in toxocaral granulomas. | clean laboratory bred albino mice were used. three mice of these were used for testing the infectivity of eggs. twenty four mice were sacrificed at 3 weeks and 3 months, 12 each time. immunohistochemical study which is a combination of immunological and pathological changes was performed to determine the differential population of inflammatory cells in the reaction produced to t. canis infection in early and late stages. | 2009 | 19795753 |
| comparative assessment of enzyme-linked immunosorbent assay and western blot for the diagnosis of toxocariasis in patients with skin disorders. | background the link between various chronic skin disorders and toxocariasis was previously demonstrated by case reports and several case-control studies. however, these previous studies were based only on the toxocara canis excretory-secretory-enzyme-linked immunosorbent assay (tes-elisa) serological technique, which is not specific due to cross-reactivity with parasites of the genera anisakis or ascaris. immunoblot analysis is highly specific and can detect very low levels of toxocara antibodie ... | 2010 | 19785612 |
| method for detecting circulating toxocara canis antigen and its application in human serum samples. | diagnosis of larval migrans (lm) is usually done by immunodiagnostic methods. these methods, however, simply show the presence or absence of antibody but not the active infection of the patients. therefore, we aimed to establish a diagnostic method for detecting circulating toxocara canis antigen using a sandwich, elisa. monoclonal antibodies (mab) were produced against the excretory-secretory (es) antigen of second-stage t canis larvae. among the mabs obtained, we selected one mab (tcmab12; mol ... | 2009 | 19769229 |
| a 63-year-old male with marked eosinophilia and dyspnoea on exertion. | 2009 | 19717710 | |
| the effects of benzimidazoles on the larval stage of toxocara cati in experimentally infected chickens. | toxocara cati (t. cati) and toxocara canis (t. canis), roundworms of cats and dogs, are zoonotic parasites that cause visceral and ocular larval migrans in human beings. humans and other paratenic hosts are infected by ingesting the infective toxocara eggs from contaminated soil, unwashed hands, contaminated raw vegetables or ingestion of under-cooked organs and muscle tissues of infected paratenic hosts such as chickens, cattle and sheep. it has been shown that the seroprevalence of toxocariasi ... | 2009 | 19696725 |
| endoparasites of red fox (vulpes vulpes) in central italy. | a parasitologic study on 129 red foxes (vulpes vulpes) from tuscany (central italy) was carried out in 2004-2006. five intestinal species were found at necropsy: dipylidium caninum (prevalence 57.3%), mesocestoides lineatus (45.4%), uncinaria stenocephala (39.1%), toxocara canis (9.1%), and toxascaris leonina (5.4%). other parasites not associated with the intestine included crenosoma vulpis (14.7%), capillaria aerophila (7.0%), angiostrongylus vasorum (7.0%), and filarial parasites (17.8%). cop ... | 2009 | 19617506 |
| field evaluation of the efficacy and safety of emodepside plus praziquantel tablets (profender tablets for dogs) against naturally acquired nematode and cestode infections in dogs. | a controlled, blinded and randomised multicentre field study evaluated the efficacy and safety of a new anthelmintic tablet formulation containing emodepside plus praziquantel (profender tablets for dogs) in the treatment of gastrointestinal nematode and cestode infections in dogs in france, germany, portugal and slovakia. dogs positive for nematodes and/or cestodes (demonstrated by faecal egg counts and/or the presence of proglottids) were treated with emodepside plus praziquantel tablets (n = ... | 2009 | 19575222 |
| efficacy of emodepside plus praziquantel tablets (profender tablets for dogs) against mature and immature infections with toxocara canis and toxascaris leonina in dogs. | the efficacy of emodepside plus praziquantel tablets (profender tablets for dogs) against mature adult, immature adult and larval stages of toxocara canis and toxascaris leonina was evaluated in ten randomised, blinded and placebo-controlled dose confirmation studies in naturally or experimentally infected dogs. the tablets were used at the proposed minimum dose of 1 mg emodepside and 5 mg praziquantel per kg body weight. efficacy was calculated based on worm counts after necropsy. five studies ... | 2009 | 19575219 |
| an unusual cause of liver masses. | 2009 | 19555439 | |
| influence of variables on centrifuge-flotation technique for recovery of toxocara canis eggs from soil. | the purpose of this study was to evaluate the influence of variables in a flotation technique for the recovery of toxocara canis eggs from soil. the trials were done under standardized conditions on one gram of previously sterilized soil samples contaminated with 200 eggs of t. canis. the following variables were evaluated in serial steps: sieving; type of wash; time of stirring; resuspension of sediment; solution flotation. centrifuge-flotation in sodium nitrate (d = 1.20 g/cm(3)) was adopted a ... | 2009 | 19551291 |
| toxocara canis: larval migration dynamics, detection of antibody reactivity to larval excretory-secretory antigens and clinical findings during experimental infection of gerbils (meriones unguiculatus). | in this study, mongolian gerbils were used to analyse features of toxocara infection that included larval migration, humoral immune responses to toxocara canis excretory-secretory antigens (tes) and aspects of host physiology. at day 10 post-infection (p.i.) most larvae were in the intestine and the lungs while later the total number of larvae was higher in the carcass tissue; the number of larvae per gram of tissue was lower elsewhere other than in the brain. infected animals showed several neu ... | 2009 | 19545524 |
| external and intestinal parasites of pet dogs with reference to zoonotic toxocariasis. | examination of 3000 pet dogs over two years at the veterinary teaching hospital, faculty of veterinary medicine revealed external and internal parasites. the external parasites were rhipicephalus sanguineus, ctenocephalus felis, sarcoptes canis, and sarcoptes scabiei. the internal parasites were echinococcus granulosus, dipylidium caninum, rare heterophyes heterophyes, and toxocara canis. toxocara eggs were detected in 9.83%. the results were discussed with reference to zoonotic toxocariasis. | 2009 | 19530631 |
| [prevalence of intestinal canine and feline parasites in saitama prefecture, japan]. | we studied the prevalence of intestinal parasites in animal companions in saitama prefecture, japan, where no detailed data is currently available. between may 1999 and december 2007, fecal samples were collected from 906 dogs and 1,079 cats in public animal shelters and examined by microscopy. overall, prevalence of intestinal parasites in dogs was 38.6% and cats 43.1%. trichuris vulpis was the most prevalent canine parasite species (22.3%), followed by toxocara canis (12.5%), ancylostoma canin ... | 2009 | 19522305 |
| high efficacy of albendazole-peg 6000 in the treatment of toxocara canis larva migrans infection. | in vitro and in vivo experiments were used to determine whether albendazole-peg 6000 solid dispersions would be effective in the treatment of toxocara canis larva migrans. | 2009 | 19497941 |
| effects of toxoplasma gondii and toxocara canis antigens on wehi-164 fibrosarcoma growth in a mouse model. | cancer is the main cause of death in developed countries. however, in underdeveloped countries infections and parasitic diseases are the main causes of death. there are raising scientific evidences indicating that parasitic infections induce antitumor activity against certain types of cancers. in this study, the effects of toxoplasma gondii and toxocara canis egg antigens in comparison with bacillus calmette guerin (bcg) (known to have anticancer distinctive) on wehi-164 fibosarcoma transplanted ... | 2009 | 19488426 |
| comparative in vitro effect of artemether and albendazole on adult toxocara canis. | since the integrity of toxocara canis cuticle is essential for the nutritive and protective functions, light and scanning electron microscopic studies were undertaken to assess, for the first time, whether artemether had any effect on the cuticle including lips and sensory organs following 24 and 48 h incubation in vitro. the results were compared with those observed in the worm cuticle following incubation in albendazole, as it was 100% effective against adult nematode. the body cover changes s ... | 2009 | 19468753 |
| seroprevalence of toxocara canis infection among asymptomatic children with eosinophilia in croatia. | a total of 142 serum specimens from croatian children aged 3-18 years, with peripheral eosinophilia and without any clinical symptoms, were tested for the presence of toxocara canis igg antibodies using an enzyme-linked immunosorbent assay (elisa) and western blot method. the overall t. canis seropositivity rate in the samples tested was 31%. there was no statistical difference in the seroprevalence rate between boys (32.1%) and girls (29.7%, chi2 = 0.092, p = 0.761). the t. canis seropositivity ... | 2009 | 19460194 |
| mri findings of spinal visceral larva migrans of toxocara canis. | the purpose of this study is to investigate the mri findings of visceral larva migrans (vls) of toxocara canis in spinal cord. | 2010 | 19447576 |
| toxocara seropositivity in sri lankan children with asthma. | toxocariasis occurs in humans due to infection with toxocara canis or t. cati, the nematode parasites of dogs and cats, respectively. the relationship between toxocariasis and asthma is complex, with some studies demonstrating that children with asthma were more likely to be toxocara seropositive as compared to non-asthmatic children, and other studies indicating no such significant relationship. the aim of the present study was to investigate toxocara seropositivity and its association with ast ... | 2009 | 19405924 |
| [toxocara canis under the microscope]. | 2009 | 19391522 | |
| muscular strength decrease in rattus norvegicus experimentally infected by toxocara canis. | the muscular strength of experimental infected rattus norvegicus with 3rd. stage toxocara canis larvae was investigated. fifty wistar rats, divided in three groups (g1-20 rats infected by 300 eggs of t. canis; g2-20 rats infected by 2,000 eggs of t. canis and g3-10 rats without infection) had been used. ten and 30 days after infection the muscular strength in the fore-feet of the rats was checked; at the same time, the body weight was determined. no significative differences in the body weight w ... | 2009 | 19390734 |
| development and evaluation of a sensitive and specific assay for diagnosis of human toxocariasis by use of three recombinant antigens (tes-26, tes-30usm, and tes-120). | diagnosis of human toxocariasis currently relies on serologic tests that use toxocara excretory-secretory (tes) antigen to detect immunoglobulin g (igg) antibodies to the larvae. in general, however, these assays do not have adequate specificity for use in countries in which other soil-transmitted helminths are endemic. the use of recombinant antigens in these assays, however, is promising for improving the specificity of the diagnosis of toxocariasis. toward this goal, we developed an igg4 enzy ... | 2009 | 19369434 |
| [the current toxocariasis situation in moscow]. | 2009 | 19348316 | |
| treatment of ocular toxocariasis with albendezole: a case report. | toxocara canis is a parasite that can infect the eye and create a significant inflammatory response that can be detrimental to the patient's vision. its clinical presentation can mimic other causes of uveitis, and its diagnosis and treatment can be challenging. prompt and accurate diagnosis of ocular toxocariasis is essential to prevent permanent visual loss. | 2009 | 19329060 |
| [toxocariasis as a cause of hypereosinophilia]. | toxocariasis is one of the causes of eosinophilia in peripheral blood and provokes eosinophilic infiltration in internal organs. in israel, the number of cases of toxocariasis is very low, 3 cases annually, according to the records at the ministry of health. many cases of eosinophilia might be misdiagnosed as hypereosinophilia syndrome (hes), if serological testing for toxocara is not conducted, leading to inappropriate treatment. the test is for specific serum igg antibody of toxocara canis ant ... | 2009 | 19320382 |
| gastrointestinal parasites in dogs from the island of st. pierre off the south coast of newfoundland. | the present work was performed to survey the gastrointestinal parasites of domestic dogs (canis lupus familiaris) and also to determine if any were infected with angiostrongylus vasorum (french heartworm), on the french island of st. pierre off the south coast of newfoundland. a total of 57 fecal samples were collected and examined for intestinal parasites. the overall prevalence of parasitism was 57.9% and the six species found were: uncinaria stenocephala/ancylostoma caninum (47.4%), toxocara ... | 2009 | 19303213 |
| ultrastructural localization of toxocara canis larval antigen reacted with a seropositive human serum. | excretory-secretory products of toxocara canis larvae have been considered as a major functional antigen in immune responses against toxocariasis. we studied ultrastructural localization of t. canis second-stage larval antigen using a seropositive human serum under immunogold electron microscopy. high-density gold particles were observed in the secretory cells, excretory duct, intestinal epithelium, and cuticle of the larval worm sections. the distribution of the positive reactions in the larval ... | 2009 | 19290095 |
| comparison of passive fecal flotation run by veterinary students to zinc-sulfate centrifugation flotation run in a diagnostic parasitology laboratory. | the sensitivity of fecal examination methods can be influenced by both technician error and methodology. in this analysis, we compared the results of 335 passive fecal flotation examinations performed on the feces of stray dogs by 3rd-yr veterinary students at the university of pennsylvania, school of veterinary medicine, to the results obtained through zinc-sulfate centrifugation performed by the diagnostic parasitology laboratory on the same fecal samples. the students' passive flotation resul ... | 2009 | 19284803 |
| impact of toxocariasis in patients with unexplained patchy pulmonary infiltrate in korea. | toxocariasis is one of the causes of pulmonary eosinophilic infiltrate that is increasing in korea. this study was designed to identify the prevalence of toxocara seropositivity in patients with unexplained pulmonary patchy infiltrate and to evaluate associated factors. we evaluated 102 patients with unexplained pulmonary patchy infiltrate on chest computed tomography (ct) scan. as a control set, 116 subjects with normal chest ct were also evaluated. history of allergic disease, drug use, parasi ... | 2009 | 19270811 |
| [zoonotic parasites in dog feces at public squares in the municipality of itabuna, bahia, brazil]. | the contamination of public squares by zoonotic potential parasites was evaluated at the urban areas in the municipality of itabuna brasil. for such, 119 fecal samples of dogs were collected at 10 public squares. after that, these feces samples were transported to the parasitology laboratory in the uesc and they were analyzed by mariano and carvalho's method. of the total analized samples, 56.3% show some parasitic evolutive form. ancylostoma sp. was the most frequently (47.9%), followed by stro ... | 2008 | 19265579 |
| toxocara canis and toxocara vitulorum: molecular characterization, discrimination, and phylogenetic analysis based on mitochondrial (atp synthase subunit 6 and 12s) and nuclear ribosomal (its-2 and 28s) genes. | toxocara canis and toxocara vitulorum are two important parasites of dogs and buffaloes with public health concern. the objectives of the present study are to identify molecular markers to discriminate these closely related parasites and to determine their phylogenetic position and genetic diversity within the genus toxocara. thus, two mitochondrial genes (complete atpase 6 and partial small subunit ribosomal rna (12s rdna)), two nuclear ribosomal genes (second internal transcribed spacer region ... | 2009 | 19221796 |
| [clinical features, the effectiveness of treatment and function of vision organ in children and adolescents with ocular toxocariasis]. | toxocariasis is caused by toxocara canis, the intestinal nematode commonly found in dogs. patients are mostly young children, with an average age of 7.5 years. patients have unilateral progressive painless vision loss and occasional leukocoria. ocular toxocariasis has a variable presentation, from localized peripheral or macular granulomas to chronic endophthalmitis. | 2008 | 19195167 |
| echinococcosis, toxocarosis and toxoplasmosis screening in a rural community in eastern kazakhstan. | to determine the extent of carnivore-transmitted parasitic zoonoses in a community in eastern kazakhstan, a region where cystic echinococcosis (ce) re-emerged in recent years. | 2009 | 19171010 |
| epidemic of unilateral panuveitis in children from brazilian amazonia: clinical and etiological aspects in seven patients. | to describe clinical presentation and results of diagnostic and therapeutic procedures in seven children from an epidemic of panuveitis in the brazilian amazonia, as well as environmental analysis and etiological aspects involved. | 2010 | 19165423 |
| giardia and other intestinal parasites in different dog populations in northern belgium. | the objectives of this study were to obtain data on the prevalence of intestinal parasites in different dog populations in northern belgium, to estimate the zoonotic risk associated with these infections and to identify potential risk factors. between 2004 and 2007 a total of 1159 faecal samples were collected from 451 household dogs, 357 dogs from breeding kennels and 351 dogs with gastrointestinal disorders. the samples from dogs with gastrointestinal disorders were sent to the diagnostic labo ... | 2009 | 19155136 |
| seroprevalence study of toxocara canis in selected egyptian patients. | this study was conducted in order to reveal the seroprevalence of t. canis infection in selected 150 egyptian patients with presumptive clinical syndromes. they were children (128) with respiratory symptoms or pyrexia of unknown origin (puo)and adults (22) with puo. anti-toxocara antibodies (igg) were detected in sera by elisa. the results showed 6.2% positivity in children. the frequency increased in male gender, those in rural residence and in 6-12 years group versus 1-6 years, and 4% & 13.3% ... | 2008 | 19143141 |
| kinetics of eosinophilia and ige production in experimental murine toxocariasis. | eosinophilia and immunoglobulin e (ige) antibody are considered the first and important elements in host responses to helminth infection. toxocara canis, which elicits prominent eosinophilia and ige production in normal mice, may be useful in understanding the kinetics of circulating peripheral blood eosinophils and ige antibody during infection. the onset, magnitude and duration of peripheral blood eosinophilia and total ige production after primary t. canis infection in female outbred albino m ... | 2008 | 19143120 |
| ocular lesions in gerbils (meriones unguiculatus) infected with low larval burden of toxocara canis: observations using indirect binocular ophthalmoscopy. | to study the frequency of ocular lesions in 30 gerbils infected with 100 embryonated eggs of toxocara canis, indirect binocular ophthalmoscopy was performed 3, 10, 17, 24, 31 and 38 days after infection. all the animals presented larvae in the tissues and 80% presented ocular lesions. hemorrhagic foci in the choroid and retina were present in 92% of the animals with ocular lesions. retinal exudative lesions, vitreous lesions, vasculitis and retinal detachment were less frequent. mobile larvae or ... | 2008 | 19142434 |
| helminth parasites of the wolf canis lupus from latvia. | thirty-four wolves were collected between 2003 and 2008 from throughout latvia and examined for helminths. a total of 17 helminth species were recorded: the trematode alaria alata (85.3%); the cestodes diphyllobothrium latum (2.9%), echinococcus granulosus (2.9%), echinococcus multilocularis (5.9%), mesocestoides lineatus (5.9%), taenia crassiceps (8.8%), taenia hydatigena (41.2%), taenia (ovis) krabbei (8.8%), taenia multiceps (47.1%), taenia pisiformis (20.6%), taenia polyacantha (11.8%), taen ... | 2009 | 19138449 |
| fulminant eosinophilic myocarditis associated with visceral larva migrans caused by toxocara canis infection. | a 19-year-old man was transferred to hospital because of myocarditis with cardiogenic shock. echocardiography showed a left ventricular ejection fraction of 23.8% and an intermediate amount of pericardial effusion. the patient immediately received an intra-aortic balloon pump and percutaneous cardiopulmonary support. right ventricular endomyocardial biopsy was performed in the acute phase and showed extensive eosinophilic inflammatory cell infiltration, severe interstitial edema and moderate myo ... | 2009 | 19122304 |
| severe infection of adult dogs with helminths in hunan province, china poses significant public health concerns. | the prevalence of helminths in adult dogs was investigated in hunan province, the people's republic of china between june 2006 and december 2007. a total of 438 adult farm dogs slaughtered in local abattoirs from 9 representative administrative regions in hunan province were examined for the presence of helminths using a helminthological approach. all collected worms were counted and identified to species according to existing keys and descriptions. a total of 11 helminth species were found in t ... | 2009 | 19091472 |
| recovering of toxocara canis eggs from samples of experimentally contaminated soil. | 2008 | 19082381 | |
| anthelmintic activity of benzimidazole derivatives against toxocara canis second-stage larvae and hymenolepis nana adults. | the anthelmintic activity of 11 benzimidazole derivatives (a1-a11) and 2 thioureides n,n'-disubstituted (b1-b2) was determined. each compound and albendazole was tested in vitro against toxocara canis larvae and in vivo against hymenolepis nana adult. compounds a1-a6 and b1-b2 were designed as albendazole prodrugs. compounds a8-a11 were designed as direct analogues of a7, which had previously proved to be an effective agent against fasciola hepatica. results of the in vitro screening showed that ... | 2009 | 19073130 |
| parasites of importance for human health in nigerian dogs: high prevalence and limited knowledge of pet owners. | dogs are the most common pet animals worldwide. they may harbour a wide range of parasites with zoonotic potential, thus causing a health risk to humans. in nigeria, epidemiological knowledge on these parasites is limited. | 2008 | 19068110 |
| [the incidence of internal parasites in dogs and cats as dependent on the level of awareness among owners]. | the objective of the present study was to determine the incidence of internal parasites in dogs and cats owned by the employees of the faculty of veterinary medicine, university of warmia and mazury in olsztyn, and by students and their families, as well as in pets presented to veterinary clinics and in animals from shelters. the study, conducted from january to may 2008, involved 135 dogs and 35 cats. feces samples were analyzed for parasites by flotation technique with the use of darling's sol ... | 2008 | 19055069 |
| [estimation of eosinophilia, immunoglobulin e and eosinophilic cationic protein concentration during the treatment of toxocariasis]. | toxocara canis and toxocara cati do not transform in human organism into a mature form and they circulate reaching various organs and tissues causing characteristic symptoms. activated eosinophils, which play a significant role in parasitic invasion, contain in their granules eosinophilic cationic protein (ecp) of strong pro-inflammatory activity. the aim of the study was to estimate the concentration of immunoglobulin e, peripheral blood eosinophilia and serum concentration of eosinophilic cati ... | 2008 | 19055065 |
| [case of toxocara canis larva migrans cured by additional treatment with albendazole]. | a 42-year-old man presented at our emergency department with fever, sputum, and dyspnea. his chest x-ray films showed ground-glass opacities mainly in the upper and middle lung fields. we diagnosed pneumonia, gave antibiotic treatment, and his symptoms improved. however he later showed eosinophilia. we performed additional workup, and diagnosed toxocara canis larva migrans. we treated him with albendazole for four weeks, but his eosinophil count rose again from the end of treatment one month lat ... | 2008 | 19044036 |
| febrile "migrating" eosinophilic cellulitis with hepatosplenomegaly: adult toxocariasis - a case report. | abstract: background: eosinophilic cellulitis (wells' syndrome) is a polyetiologic clinical entity with still obscure pathogenesis. clinically overt toxocariasis is uncommon in adults, yet helminthozoonoses, including toxocariasis have been occasionally implicated in the pathogenesis of eosinophilic cellulitis. case representation: a 55-year-old female patient presented with a skin biopsy verified recurring febrile eosinophilic cellulitis, blood eosinophilia (42%), slight anaemia (hct 35%), hepa ... | 2008 | 19038064 |
| transvitreal migration of a toxocara larva resulting in a second chorioretinal granuloma. | 2008 | 18991049 | |
| urban contamination with zoonotic parasites in the central region of argentina. | adult worms develop in dogs and their eggs are shed in the feces. non-embryonated eggs of toxocara canis become infectious after about 2-6 weeks in the soil and the likelihood of their transmission to humans is through ingestion. in 2004 studies were carried out in the areas of urban recreation in the central region of argentina. a total of 393 dog excrement samples were collected in eight different cities: 59.3 per cent were positive for parasites. these areas of urban recreation are contaminat ... | 2008 | 18977705 |
| [analysis of children with a presumptive diagnosis of toxocariasis in santa fe, argentina]. | human toxocariasis is a parasitic disease found worldwide. the most important etiological agent is toxocara canis, a dog parasite. humans are infected by the ingestion of their eggs; the eggs hatch in the small intestine and the larvae migrate through the capillaries, taking up residence in different tissues. clinical manifestations are associated with mechanical and/or reaction damage caused by these parasites larvae. clinical diagnosis is difficult. the method applied in this work is the demon ... | 2008 | 18977703 |
| cystic hydatidosis: a zoonotic silent health problem. | examination of five hundred pet dogs revealed echinococcus granulosus in nine dogs, dipylidium caninum in twenty dogs, and toxocara canis in thirty dogs. the risky role played by pet dogs in the transmission and spreading of zoonotic cystic hydatidosis was discussed. | 2008 | 18853634 |
| the prevalence and intensity of gastrointestinal parasites of dogs in ile-ife, nigeria. | a study of gastrointestinal parasites in 269 faecal samples from dogs (canis familiaris) collected from ile-ife, nigeria between january and december 2004, revealed seven helminth species: toxocara canis 33.8%, ancylostoma sp. 34.6%, toxascaris leonina 3.3%, trichuris vulpis 3.7%, dipylidium caninum 4.1%, uncinaria stenocephala 0.7% and taenia sp. 1.1%. the faecal egg intensities, determined as mean eggs per gram of faeces ( +/- sem) were: t. canis 393.8 +/- 83.4, ancylostoma sp. 101.5 +/- 32.8, ... | 2009 | 18838021 |
| high prevalence of intestinal zoonotic parasites in dogs from belgrade, serbia--short communication. | to identify areas of risk for canine-related zoonoses in serbia, the aim of this study was to provide baseline knowledge about intestinal parasites in 151 dogs (65 household pets, 75 stray and 11 military working dogs) from belgrade. the following parasites, with their respective prevalences, were detected: giardia duodenalis (14.6%), ancylostomatidae (24.5%), toxocara canis (30.5%), trichuris vulpis (47.0%) and taenia-type helminths (6.6%). of all examined dogs, 75.5% (114/151) were found to ha ... | 2008 | 18828485 |
| current trends in tissue-affecting helminths. | some helminths have by their evolution learnt to systemically invade a host organism, and to select specific organs or host cell types as predilection site to reside, maturate or even proliferate. these parasites needed to develop complex and unique strategies to escape host immune reactions. the present work sheds some light into the strategy developed by three different helminths (echinococcus multilocularis, trichinella spiralis and toxocara conis) to survive in the host organ or host cell, r ... | 2008 | 18814697 |
| prevalence of dog intestinal parasites and risk perception of zoonotic infection by dog owners in são paulo state, brazil. | coprological examination was used to estimate the prevalence of gastrointestinal parasites in stray and domiciled dogs from botucatu, são paulo state, brazil. risk factors for dog infection were assessed in relation to demographic, husbandry and management data. the dog owners completed a questionnaire survey on some aspects of dog parasitism such as parasite species, mechanisms of infection, awareness of zoonotic diseases and history of anthelmintic usage. parasites were found in the faeces of ... | 2008 | 18811905 |
| [toxocariasis in children--difficult clinical problem]. | toxocariasis in humans is a zoonosis due to the migration of toxocara canis or t. cati larvae in human body. this review provides basic information on pathology of infection and clinical signs and symptoms of toxocariasis in children. the cases diagnosed in the recent years in central poland are presented. the disease was recognised accidentally based on the results of laboratory analysis performed for other reasons, when abnormalities suggesting an active helminthiasis were found (eosinophilia, ... | 2008 | 18807488 |
| production of monoclonal antibodies against the 8 kda subunit of echinococcus granulosus antigen b (egagb8/2) using dna immunization. | cystic echinococcosis (ce), an endemic cosmopolitan zoonotic helminthic disease caused by the larval stage of echinococcus granulosus, lacks reliable diagnostic tools that fulfill the criteria of high sensitivity and specificity. antigen b (agb), a thermostable lipoprotein that constitutes a considerable fraction of the cystic hydatid fluid (hf), is being considered as a suitable source for vaccination and immunodiagnosis of ce due to its high specificity. genetic immunization was used to immuni ... | 2008 | 18803505 |
| a familial case of visceral toxocariasis due to consumption of raw bovine liver. | we present 3 adult cases of visceral toxocariasis from the same family, who each consumed thin slices of raw bovine liver weekly, and developed eosinophilia and multiple small lesions in their livers and lungs. serological examinations using the larval excretory-secretory product of toxocara canis strongly indicated infection with toxocara species larvae. the patients responded well to treatment with albendazole. ingestion of raw liver from paratenic animals is considered to be a common transmis ... | 2008 | 18771749 |
| toxocariasis associated with chronic cough in childhood: a longitudinal study in hungary. | chronic cough lasting 8 weeks or more often seems to be an intractable problem in childhood. toxocara infection is associated with an increased prevalence of airway symptoms and may be the possible aetiological agent of chronic cough. of 425 children aged 2-17 years with chronic cough who were investigated for toxocariasis and the distribution of bronchial asthma (ba), cough variant asthma (cva) and non-asthmatic eosinophilic bronchitis (naeb), 136 (32%) were seropositive for toxocara canis anti ... | 2008 | 18752712 |
| four abundant novel transcript genes from toxocara canis with unrelated coding sequences share untranslated region tracts implicated in the control of gene expression. | the toxocara canis "abundant novel transcripts" (ant) are four highly expressed products, constituting >18% of ests from the infective stage of this widely prevalent nematode parasite. using 5' race, we determined full-length sequences for each ant gene, between 1.8 and 2.8kb. the four genes (termed ant-3, -5, -30 and -34), share no coding sequence similarity, although their 3'utrs (untranslated regions) are homologous. predicted ant-5 and ant-30 proteins show distant similarity to rna regulator ... | 2008 | 18703093 |
| cognitive dysfunction, urinary retention, and a lesion in the thalamus--beware of possible toxocariasis of the central nervous system. | toxocariasis of the central nervous system is usually characterized by an eosinophilic meningitis, encephalitis or myelitis. we here report a patient with an at least 7 years history of unexplained neurologic signs and symptoms. mri showed a cystic lesion in the left thalamus, compatible with a parasitic infection. blood and csf analyses were positive for toxocara canis igg western-blot, but were otherwise unremarkable. the case report raises the question whether there are chronic or late varian ... | 2008 | 18687519 |
| serodiagnosis of toxocara antibodies among infants and pregnant women suspected of ocular or visceral toxocariasis using two types elisa antigens. | the diagnosis of toxocariasis heavily depends on immunological tests because the number of parasites is usually few in infected tissues, unless they migrate into an organ such as eye. in general, patients with ocular toxocariasis have serum anti-t canis antibody titres that are significantly lower than those with visceral toxocariasis. | 2006 | 18685178 |
| the mitochondrial genome of toxocara canis. | toxocara canis (ascaridida: nematoda), which parasitizes (at the adult stage) the small intestine of canids, can be transmitted to a range of other mammals, including humans, and can cause the disease toxocariasis. despite its significance as a pathogen, the genetics, epidemiology and biology of this parasite remain poorly understood. in addition, the zoonotic potential of related species of toxocara, such as t. cati and t. malaysiensis, is not well known. mitochondrial dna is known to provide g ... | 2008 | 18682828 |
| encroachment of echinococcus granulosus into urban areas in eastern queensland, australia. | to investigate the prevalence of echinococcus granulosus in wild dogs (dingos and dingo-domestic dog hybrids) living in and around human habitation on fraser island and in townships of the maroochy shire, on queensland's sunshine coast, australia. | 2008 | 18673469 |
| possible intrafamilial transmission of toxocara causing eosinophilic meningitis in an infant. | human toxocariasis can result from the inadvertent ingestion of embryonated eggs of toxocara canis or toxocara cati from environmental sources such as dirt, sand, or foods carrying contaminated soil. we report a case in an infant resulting in eosinophilic meningitis and prolonged fever. the case illustrates probable intrafamilial transmission, a mode of transmission that has not been previously documented. | 2008 | 18664926 |
| prolactin evokes lactational transmission of larvae in mice infected with toxocara canis. | we investigated the trans-lactational maternal-neonatal transmission of toxocara canis larvae in mice, with particular interest in the role of prolactin in their migration to the mammary gland. two female mice were infected with 300 t. canis eggs soon after delivery of 27 offspring. after 1 week of breast-feeding, seven larvae were recovered from 4 of 13 offspring. after 2 weeks of lactation, 101 larvae were recovered from all the remaining offspring. daily prolactin administration (5 microg) wa ... | 2008 | 18664391 |
| blood-brain barrier impairment with enhanced sp, nk-1r, gfap and claudin-5 expressions in experimental cerebral toxocariasis. | infection by toxocara canis in humans may cause cerebral toxocariasis (ct). appreciable numbers of t. canis larvae cross the blood-brain barrier (bbb) to invade the brain thus causing ct. in the present studies, we evaluated the bbb permeability and bbb injury as assessed by the cerebral evans blue (eb) concentration as well as by pathological changes and glial fibrillary acidic protein (gfap) expression in t. canis -infected mice monitored from 3 days (dpi) to 8 weeks post-infection (wpi). the ... | 2008 | 18627507 |
| human toxocariasis in rural brazilian amazonia: seroprevalence, risk factors, and spatial distribution. | this population-based cross-sectional study of 403 rural settlers in brazilian amazonia revealed an overall rate of igg seropositivity to toxocara canis excretory-secretory larval antigen of 26.8% (95% confidence interval [ci], 22.5-31.4%). multilevel logistic regression analysis identified current infection with hookworm (odds ratio [or], 2.32; 95% ci, 1.11-4.86) and residence in the most recently occupied sectors of the settlement (or, 1.81; 95%ci, 1.3-2.52) as significant risk factors for tox ... | 2008 | 18606770 |
| contamination of fox hair with eggs of toxocara canis. | eighty-seven red foxes were investigated for the presence of toxocara eggs on a sample of their hair from the peri-anal region. the worm burden of toxocara in each fox intestine was also assessed and the relationship between eggs on the hair and worms in the intestine explored. twenty-eight per cent of the foxes were found to have toxocara eggs on their hair, with an average of 1.31 +/- 3.21 eggs per gram of hair (+/- sd). sixty-one per cent of foxes harboured toxocara worms within their intesti ... | 2008 | 18577302 |
| an improved method for recovery of muscle-stage larvae from mice infected with toxocara canis. | we report a modified digestion method that improves the recovery of toxocara canis larvae from skeletal muscle. minced muscle tissue from infected mice was incubated in artificial gastric juice for 48 hr at 37 c, and ethanol was added for the second 24 hr. this procedure allowed the larvae to be identified and counted more quickly than with the standard digestion method. this method allows measurement of the total number of larvae present in muscle tissue following oral intubation of embryonated ... | 2008 | 18576836 |
| development of a highly sensitive igg-elisa based on recombinant arginine kinase of toxocara canis for serodiagnosis of visceral larva migrans in the murine model. | toxocariasis is a worldwide zoonotic disease caused by the ascarid nematode toxocara canis. the most common method available for serodiagnosis of toxocariasis is an enzyme-linked immunosorbent assay (elisa) test using toxocara excretory-secretory antigen (tes). the present study describes the development of igg-elisa based on antiserum prepared against the recombinant arginine kinase of toxocara canis. antiserum was prepared against the purified recombinant arginine kinase (ak) using 6-week-old ... | 2008 | 18575890 |
| brain injury-associated biomarkers of tgf-beta1, s100b, gfap, nf-l, ttg, abetapp, and tau were concomitantly enhanced and the ups was impaired during acute brain injury caused by toxocara canis in mice. | because the outcomes and sequelae after different types of brain injury (bi) are variable and difficult to predict, investigations on whether enhanced expressions of bi-associated biomarkers (biabs), including transforming growth factor beta1 (tgf-beta1), s100b, glial fibrillary acidic protein (gfap), neurofilament light chain (nf-l), tissue transglutaminases (ttgs), beta-amyloid precursor proteins (abetapp), and tau are present as well as whether impairment of the ubiquitin-proteasome system (u ... | 2008 | 18573219 |
| detection of helminth infections in dogs and soil contamination in rural and urban areas. | a study was conducted to determine the helminthes in dog's feces and soil samples from urban and rural areas. six species of nematodes (toxocara sp, an undetermined nematode larvae, strongyloides sp larvae, ascaris sp ova, hookworm ova, trichuris sp ova) and one species of cestode (taenia sp) were found in 175 stool samples. seventy-eight point nine percent of stool samples were positive for helminthes. mixed infection with at least one parasite was found in 32.6% of the samples. the prevalence ... | 2008 | 18564703 |
| human toxocariasis: a report of nine cases. | human toxocariasis is caused by infection with the larval stage of nematode parasites of dogs and cats, toxocara canis or toxocara cati. these helminths are not able to complete their life cycle in undefinitive hosts and so undergo aberrant migrations in the tissues causing a wide spectrum of signs and symptoms. eosinophilia is often severe and sometimes represents the only sign of infection, except in ocular and neurological forms. | 2008 | 18554274 |
| initial stage of development and migratory behavior of toxocara canis larvae in balb/c mouse experimental model. | in the present study, the initial developmental stage of toxocara canis eggs and larvae, and number of recovered larvae from balb/c mouse-infected organs are described. in vitro culture of t. canis detects the frequencies of interphasic, mitotic and embryonated eggs only within a 7-day period. analysis by egg counting was carried out for 32 days. the results showed that at 7 days after cultivation, the frequency of larvae was 50.4% and that this frequency reached 52.8% in 32 days. in the experim ... | 2008 | 18551411 |
| electrophoretic analysis of sequence variability in three mitochondrial dna regions for ascaridoid parasites of human and animal health significance. | sequence variability in three mitochondrial dna (mtdna) regions, namely cytochrome c oxidase subunit 1 (cox1), nadh dehydrogenase subunits 1 and 4 (nad1 and nad4), among and within toxocara canis, t. cati, t. malaysiensis, t. vitulorum and toxascaris leonina from different geographical origins was examined by a mutation-scanning approach. a portion of the cox1 gene (pcox1), a portion of the nad1 and nad4 genes (pnad1 and pnad4) were amplified separately from individual ascaridoid nematodes by po ... | 2008 | 18546167 |
| [case of toxocariasis showing migratory nodular shadows with halos]. | a 30-year-old man, who had kept a dog for nine years and often ate raw beef liver, visited a hospital because of a chest nodular shadow in the left lung field found on a checkup examination. chest computed tomography obtained 8 days after the checkup showed no abnormal shadow in the left lung but two nodular shadows with halos in the right upper and lower lobes. peripheral blood eosinophil counts and serum ige values were elevated. immunological examination including microplate elisa showed a hi ... | 2008 | 18517021 |
| sero-epidemiology of toxocariasis in a rural settlement in são paulo state, brazil. | the seroprevalence of toxocara canis and risk factors for infection with this parasite were explored in a rural settlement in são paulo state, brazil. total iga and ige levels in 79 subjects were determined by turbidimetry and chemiluminescence, respectively. total counts of leucocytes and erythrocytes and differential counts of leucocytes were made by flow cytometry. elisa for the detection of anti-toxocara igg, iga and ige were standardized using toxocara excretory-secretory antigens (tes) obt ... | 2008 | 18510815 |
| toxocara canis larval excretory/secretory proteins impair eosinophil-dependent resistance of mice to nippostrongylus brasiliensis. | survival of parasitic helminths within a host requires immune evasion and excretory/secretory (es) proteins may contribute to this process. eosinophils are important effector cells in immunity of mice to the nematode nippostrongylus brasiliensis and eosinophilic interleukin-5 transgenic (il-5 tg) mice are highly resistant to the earliest stages of primary infections. in contrast, toxocara canis is largely resistant to eosinophils, with viable larvae encysted in tissues often surrounded by these ... | 2008 | 18507784 |
| the complete mitochondrial genomes for three toxocara species of human and animal health significance. | studying mitochondrial (mt) genomics has important implications for various fundamental areas, including mt biochemistry, physiology and molecular biology. in addition, mt genome sequences have provided useful markers for investigating population genetic structures, systematics and phylogenetics of organisms. toxocara canis, toxocara cati and toxocara malaysiensis cause significant health problems in animals and humans. although they are of importance in human and animal health, no information o ... | 2008 | 18482460 |
| selenium supplementation enhances the protective response to toxocara canis larvae in mice. | the effect of oral and intraperitoneal supply of sodium selenite on the immune response to, and the course of t. canis larvae infection in mice were determined. the number of worms in the host tissue was reduced but the migratory route of larvae was not affected. selenite (se) supplementation influences se retention in the liver, enhanced il-5 and eosinophil responses and evoked il-6 production in mice infected with t. canis. the enhanced protection in mice given se intraperitoneally was associa ... | 2008 | 18482223 |
| il-5 drives eosinophils from bone marrow to blood and tissues in a guinea-pig model of visceral larva migrans syndrome. | this study was undertaken to evaluate the role of il-5 in eosinophil migration and in the maintenance of eosinophilia in a guinea-pig model of visceral larva migrans syndrome. the results show that the infection of animals with toxocara canis induced an early increase in serum il-5 levels that might be essential for eosinophil differentiation and proliferation and for the development of eosinophilia. when infected guinea-pigs were treated with mab anti-il-5 (trfk-5) given at the same time or 1 o ... | 1996 | 18475693 |
| toxocara seroprevalence in schizophrenic patients in turkey. | to investigate the seroprevalence of toxocariasis in patients diagnosed as schizophrenia. | 2008 | 18452258 |
| an improved method to obtain antigen-excreting toxocara canis larvae. | toxocara canis is a dog helminth which causes visceral larva migrans (vlm) when infecting humans as a larva. the infection is demonstrated by detecting igg antibodies against excretory-secretory larval antigens (esla) in serum by elisa. the production of esla involves the collection of adult worms from dog puppy stools, the separation of eggs from dissected uteri, and the in vitro growing of egg-derived larvae, following the time-consuming and laborious protocol described by de savigny [de savig ... | 2008 | 18439580 |
| larval migration of toxocara canis in piglets and transfer of larvae from infected porcine tissue to mice. | visceral larva migrans (vlm), caused by toxocara canis larvae in humans, animals and birds, is now well documented throughout the world. seven piglets were infected orally with 5 x 104 embryonated eggs and the migration and distribution of t. canis larvae in the tissues were evaluated. after artificial gastric juice digestion, larval yields at necropsy from different organs and muscles on days 1, 3, 7, 15 and 30 post-infection (dpi) revealed 3.05, 0.97, 0.21, 0.13, 0.05, 0.14% recovery from live ... | 2008 | 18416883 |
| follow-up of antibody avidity in balb/c mice infected with toxocara canis. | in human toxocara canis infection, an association has been shown between high igg avidity in the chronic phase and low igg avidity in recently acquired toxocarosis. the evolution of the antibody response in terms of avidity has been carried out through a t. canis infection in balb/c mice. infection with t. canis embryonated eggs (ee) was carried out with single doses (sd) of 6, 12, 50, 100, 200 or 1000 ee/mouse and with multiple doses (md) of 200 and 1000 ee. specific antibodies against t. canis ... | 2008 | 18413003 |
| [differential diagnosis of retinoblastoma: a retrospective study of 486 cases]. | detail the most frequent problems encountered in the differential diagnosis of retinoblastoma. | 2008 | 18401317 |
| detection of endoparasites with zoonotic potential in dogs with gastrointestinal disease in the uk. | we report a substantial prevalence study in symptomatic pet dogs of important zoonotic parasitic enteric infections. a total of 4526 dogs which had a faecal sample submitted to a diagnostic laboratory in the uk between 2003 and 2005 were included in the study. the most common parasite was giardia spp., which was found in 380/4526 dogs (8.4%, 95% ci 7.6-9.2%). surprisingly, cryptosporidium spp. infection was detected in only 29/4526 (0.6%, 95% ci 0.4-0.9%). toxocara canis was found in 63/4526 dog ... | 2008 | 18397497 |
| seasonal fluctuations in prevalence of dog intestinal parasites in public squares of mar del plata city, argentina and its risk for humans. | the aim of this work is to analyze whether there is a seasonal prevalence of parasites in dog feces from public squares in mar del plata city, argentina, and to evaluate the climatic conditions that promote the development of parasites and allow the transmission to people. the study was performed in 21 squares from june 2001 to may 2002. samples were processed by the willis technique. differences in prevalence of parasites were examined for significance by the chi-square test. climatic data were ... | 2007 | 18390156 |
| prevalence of anti-t. canis antibodies in stray dogs in mexico city. | toxocara canis is a common intestinal helminth found in dogs. in humans, it is a cause of visceral larva migrans (vlm), a zoonosis rarely studied in mexico. the aim of this study is to examine, by means of the indirect haemaglutination test (ihat), the prevalence of antibodies of t. canis in the serum of stray dogs in mexico city. | 2008 | 18387747 |
| prevalence of echinococcosis in street dogs in tripole district, libya. | cystic echinococcosis due to e. granulosus is a serious public health and livestock economy problem in libya. kato thick smear examination of 50 street dogs stools showed that they had echinococcus granulosus (58%), taenia spp. (14%), diplydium caninum (16%), toxocara canis (121%) and 20% were parasite-free. the stool examination using kato thick smear was more sensitive and more specific that the indirect haemaggutination test. the results were discussed with general review of the disease in li ... | 2007 | 18383781 |
| congenital asplenia and severe visceral toxocariasis. | 2008 | 18382383 | |
| seroprevalence of toxocariasis among healthy people with eosinophilia. | the aim of this study is to determine the toxocara seropositive rate among healthy people with eosinophilia. a total of 97 people residing in seoul who were healthy and whose blood eosinophilia was over 10%, as shown by regular health check-ups in 2004, were subjected to this study. their sera were tested by immunoblotting and elisa with the antigen of larval toxocara canis excretory-secretory (es) protein. sixty-five sera were band-positive (67.0%). the seropositve control sera were positive to ... | 2008 | 18344674 |
| application of toxocara canis excretory-secretory antigens and igg subclass antibodies (igg1-4) in serodiagnostic assays of human toxocariasis. | a major problem in the serodiagnosis of human toxocariasis in tropical countries is cross-reaction with antibodies to other helminthic diseases and a lack of sensitivity. the majority of tests currently available use total igg and, in this study, the use of peroxidase-conjugated anti-human igg subclass antibodies (igg1-4) was compared with total igg for the diagnosis of human toxocariasis by using toxocara excretory-secretory (tes) antigens in an enzyme-linked immunosorbent assay (elisa) format. ... | 2008 | 18343348 |