Publications

[sample preparation for pcr from pathological specimens].		2006	1383581
biochemical and functional characterization of the leucocyte tyrosine phosphatase cd45 (cd45ro, 180 kd) from human neutrophils. in vivo upregulation of cd45ro plasma membrane expression on patients undergoing haemodialysis.	the biochemical and functional characterization, and the regulation of plasma membrane expression of the leucocyte tyrosine phosphatase cd45, have been investigated in neutrophils from healthy donors and patients undergoing haemodialysis. cd45 proteins of 180 kd and 130-150 kd were precipitated from neutrophils from both healthy subjects and haemodialysed patients. prolonged storing, as well as trypsin treatment of samples containing the 180-kd cd45 protein, generated the 130-150-kd polypeptides ...	1992	1370931
characterization of guanosine diphospho-d-mannose dehydrogenase from pseudomonas aeruginosa. structural analysis by limited proteolysis.	alginate is believed to be a major virulence factor in the pathogenicity of pseudomonas aeruginosa in the lungs of patients suffering from cystic fibrosis. guanosine diphospho-d-mannose dehydrogenase (gdpmannose dehydrogenase, ec 1.1.1.132) is a key enzyme in the alginate biosynthetic pathway which catalyzes the oxidation of guanosine diphospho-d-mannose (gdp-d-mannose) to gdp-d-mannuronic acid. in this paper, we report the structural analysis of gmd by limited proteolysis using three different ...	1992	1370473
hypertension, in black and white.		2006	1347368
imaging of the knee.	acute and chronic knee dysfunction is a common clinical problem faced by physicians treating patients with musculoskeletal disorders. while standard roentgenograms provide most of the information needed to assess these disorders, the role of magnetic resonance imaging (mri) is rapidly increasing in the diagnostic evaluation of soft-tissue, ligament, tendon, and osseous abnormalities. this article focuses on the role of mri in the evaluation of disorders of the knee.	2005	1343573
alpha 2-adrenoceptor density in forebrain areas of zucker rats: no effect of genetic obesity or antiglucocorticoid treatment.	the density of alpha 2-adrenoceptors was determined in different forebrain regions of lean and obese zucker rats by para-[125i]iodoclonidine ([125i]pic) receptor autoradiography. no significant differences were observed between the zucker phenotypes in the density of alpha 2-adrenoceptors in any brain areas examined. four days treatment with the antiglucocorticoid mifepristone (ru 38486) did not affect [125i]pic-binding. it is concluded that the hyperphagia and abnormal corticosterone secretion ...	1992	1322226
leukotriene b4 omega-oxidation by human polymorphonuclear leukocytes is inhibited by pyocyanin, a phenazine derivative produced by pseudomonas aeruginosa.	human polymorphonuclear leukocytes (pmnl) metabolize the potent chemotaxin leukotriene b4 (ltb4) by omega-oxidation to 20-hydroxyl-ltb4 and 20-carboxy-ltb4. the ability of unstimulated human pmnl to metabolize exogenous ltb4 was found to be inhibited by pyocyanin, a phenazine derivative produced by pseudomonas aeruginosa, in a dose-dependent manner. 1-hydroxyphenazine (1-ohp), a metabolite of pyocyanin, was not inhibitory under identical conditions. the initial enzymic step in the conversion of ...	1992	1316878
gastric uptake of gallium-67 in aids.	we describe gastric localization of 67ga in 13 patients with acquired immunodeficiency syndrome (aids) among 148 referred primarily to rule out pneumocystis carinii pneumonia (pcp). endoscopic biopsies in five of the patients indicated cytomegalovirus (cmv) infection in one, gastritis in two, and normal tissue in two. other associated, but nongastric, infections in these 13 patients included esophageal candidiasis, pcp, mycobacterium avium-intracellulare (mai) complex, coccidioidomycosis, toxopl ...	1992	1314894
[florence nightingale: her personality, her life. importance of observation of "not doing well"].		2005	1305247
structural and functional analyses of the repressor, rbsr, of the ribose operon of escherichia coli.	the dna sequence encoding the rbs repressor protein, rbsr, has been determined. amino acid sequence analyses of the product of an rbsr-lacz fusion and of affinity-purified rbsr demonstrate that translation begins at an unusual codon, ttg, and that the initial amino acid is removed during maturation of the protein. dna-binding assays indicate that rbsr binds to a region of perfect dyad symmetry spanning the rbs operon transcriptional start site and that the affinity for the rbs operator is reduce ...	1992	1304369
a comparative study of gluconolactone versus benzoyl peroxide in the treatment of acne.	alpha hydroxy acids (aha's) or "fruit acids" are a special group of organic acids found in many natural foods. they have been described in the literature for the treatment of a number of conditions in which abnormal keratinization consistently contributes to pathogenesis. these include the icthyoses, warts, psoriasis, eczema and acne. we have performed a double-blind clinical trial on 150 patients to evaluate the efficacy and skin tolerance of the alpha hydroxy acid gluconolactone 14% in solutio ...	2003	1303072
treatment of disseminated renal cell cancer with combinations of interleukin-2, lymphokine-activated killer cells, and alpha-interferon.		2001	1301583
aids update.		2001	1301521
more about avulsed primary teeth.		2000	1301050
atlas of cancer mortality in the european economic community.		1999	1300297
[road violence among young people aged 15-24 years].	during the last decade, the annual number of deaths by road accident in france was approximatively 10,000 whose 3,000 aged 15-24. road accidents were, and remain, the first cause of death among youngsters and young adults, preceding suicide. since the early 70's, public authorities were aware of the problem and laws and regulations were implemented, aimed at curbing the disastrous trend. some results were obtained, but the situation is far from satisfactory. social, economic, psychological condi ...	1999	1300240
[exchange--from lithuania to aarhus].		2004	1299024
acetazolamide and urinary stone formation.		2005	1266368
attenuated, streptomycin-dependent salmonella typhi oral vaccine: potential deleterious effects of lyophilization.	four studies were done with streptomycin-dependent salmonella typhi as an oral, attenuated vaccine. studies 1 and 3 employed freshly harvested vaccine, whereas studies 2 and 4 involved lyophilized vaccine. five to eight doses (3 x 10(10)-10(11) organisms/dose) were given; oral streptomycin (1.0 g) was administered concomitantly in studies 2 and 3, with only two of the doses of vaccine in study 1, and was not given in study 4. no adverse reactions were encountered in 179 vaccinated men, and 94% o ...	1976	1262709
interactions of cadmium and selenium in rat plasma in vivo and in vitro.	75se and 109cd tracers were used to study the binding of se and cd to plasma proteins at various seo32- doses and times upt to 24 h after the simultaneous subcutaneous administration of seo32- markedly increased both se and cd plasma levels over that in control animals. gel permeation chromatography of plasma indicated that at all times up to 24 h cd and se were bound in an atomic ratio of approx. 1 : 1 in 330 000 and 130 000 dalton fractions. from 4 to 24 h, cd and se appeared in the 420 000 da ...	1976	1260013
[practical evaluation of methods in pharmacokinetics].	a short discussion of the differences between kinetic processes of zero and first order is followed by an outline of evaluation methods used in pharmacokinetic practice, e.g. "paper and pencil methods" as well as the use of digital and analog computers. the increasing potency of new drugs requires not only more sophisticated methods of analysis and expensive facilities but also more complex models to generate pharmacokinetic information.	2005	1242344
prognosis in coronary heart disease.		2002	1222554
impairment of proteoglycan-collagen interaction in early experimental osteoarthrosis.		1975	1221943
spectrophotometric method for estimation of carbachol in eye drops in presence of its degradation products.		1998	1219764
total exchangeable and red cell potassium in patients with chronic renal failure.		1996	1217999
[bile and stress ulcer in the rat (author's transl)].	the influence of bile on the ulcer formation under "restraint stress" condition was studied in rats with direct choledocho-gastrostomia resp. bile duct ligation. after 9 hrs. of immobilisation in plaster cuffs the animals with unrestricted bile flow via the choledochosstress gastrostomia showed as many ulcers as the sham-operated controls. there was no difference in the ulcer localisation, the region of the bile duct anastomosis was without any ulcer. after bile duct ligation the ulcer frequency ...	1975	1214546
[inhibiton of isocitrate dehydrogenase and isocitrate lyase from acinetobacter calcoaceticus by acids of the citrate and glyoxylate cycle].	acinetobacter calcoaceticus contains two forms of nadp+-dependent isocitrate dehydrogenases differing, among others, by their molecular weights and regulatory properties. the regulation of the high-molecular form of isocitrate dehydrogenase and of isocitrate lyase by organic acids, either belonging or related to the citrate and glyoxalate cycle, is investigated. while alpha-ketoglutarate and oxalacetate competitively inhibit the isocitrate dehydrogenase against ds-isocitrate, glyoxylate and pyru ...	1975	1199592
[study of influenza viral antibodies and serum inhibitors in inbred mice against a background of rations with a varying correlation of fats and carbohydrates].		2005	1199580
chromosome assignments of genes in man using mouse-human somatic cell hybrids: association of diphtheria toxin sensitivity with chromosome 5.		1975	1192802
[metabolism and degradation of phenylethylamines in plant cell suspension cultures (author's transl)].		2005	1187862
[osteotomy of tuberositas tibiae in supracondylar femoral fractures].		2005	1186704
xeromammography at a community hospital. a year's experience.		2005	1183210
[three cases of leukemia following cytopenia, possibly a preleukemic stage, of a long duration, with special reference to the characteristics of their autopsy findings (author's transl)].		2005	1172046
[autognostic human activities].		1975	1137908
choices.		2005	1069689
[clefts, oligodontia and supernumerary teeth various manifestations of a disease entiting hypothesis].		2005	1062876
rate of alcoholism diagnoses in community mental health centers: the effect of the presence of an alcoholism treatment program.	in this study, it was hypothesized that community mental health centers (cmhcs) with distinct alcoholism treatment programs (atps) would diagnose alcohol problems at a greater frequency than would centers without atps. it was also hypothesized that psychoses, personality disorders, and transient situational disturbances would be diagnosed more frequently in cmhcs without atps. yearly diagnostic admission data from nine of nebraska's cmhcs (four with atps, five without) were used. it was found th ...	2005	552314
[lumbosacral radiculography with dimer-x and amipaque. advantages, side effects and possible late complications].		2005	551604
[renal parenchymatous suppurations].		2004	545586
a time to live, a time to grieve: patterns and processes of mourning among the yolngu of australia.	anthropological studies of mortuary ceremonies have focused primarily on their social and structural correlates and functions. little attention has been given to their role in facilitating the expression and resolution of grief by the bereaved. the elaborate and extended mortuary rites of the people of northeastern arnhem land, australia (the "murngin") have several characteristics which promote and structure the mourning process and facilitate the full reintegration of the bereaved into the soc ...	2004	535408
central properties of alpha-allophanyl-alpha-allyl-gamma-valerolactone (valofan) [proceedings].		2004	526756
fate of fragments and properties of translocations of holokinetic chromosomes after x-irradiation of mature sperm of tetranychus urticae koch (acari, tetranychidae).	after irradiation of mature sperm in males of tetranychus urticae, early cleavage stages were scored for chromosome fragments. as expected from the presumed holokinetic nature of the chromosomes, the majority (94.29%) of the fragments pass mitosis without difficulty. a minority of the fragments is affected by loss (4.76%) or missegregation (0.95%), leading to loss of fragments from cells in a large fraction of fragment-containing eggs after a few divisions. lethality induced by the irradiation t ...	2004	522871
intrauterine devices.	your correspondent a. g. mathew (journal, july 14) has touched on a number of aspects of the iud which are well-known to workers in the field but which need constant reiteration. iuds in nulliparous women are imperfect and hazardous for several reasons. the nulliparous woman is usually young and for this reason, the pregnancy rate is higher. this fact, incidentally, was pointed out many years ago in the journal by a. m. hill whose obituary appeared in the above-mentioned issue. the symptoms of m ...	2004	514162
regional lung function following hip arthroplasty and preoperative normovolemic hemodilution.	the effect of preoperative normovolemic hemodilution with dextran 70 as dilutional agent on postoperative regional lung function was evaluated in patients undergoing hip arthroplasty in the lateral decubitus position. the major part of the surgical blood loss of these patients was replaced with the received autologous blood. the results obtained were compared to changes in a group of patients in whom the operative bleeding was replaced with bank blood. regional lung function, as studied with xe1 ...	2004	484181
[use of nonachlazine in the treatment of chronic ischemic heart disease].		1996	452467
aneuploidy in mouse fetuses after paternal exposure to x rays.		1979	450138
transventricular blood vessels in the third ventricle of the armadillo brain.	transventricular filaments were observed with scanning electron microscopy on the dorsolateral wall of the infundibular recess of the third ventricle of the armadillo brain. two to seven transventricular filaments per animal were present in 6 of 18 animals. there were two types of transventricular filaments, ciliated and bare. using transmission electron microscopy, we determined that these filaments consisted of a single, central capillary surrounded by ciliated ependymal cells and a small accu ...	2004	443562
[a new diagnostic test for acute myocardial infarction-immunologic measurement of myoglobin (author's transl)].		2003	430882
computer-assisted static/dynamic renal imaging: a screening test for renovascular hypertension?	computer-assisted static/dynamic renal imaging with [197hg] chlormerodrin and [99mtc]pertechnetate was evaluated prospectively as a screening test for renovascular hypertension. results are reported for 51 patients: 33 with benign essential hypertension and 18 with renovascular hypertension, and for 21 normal controls. all patients underwent renal arteriography. patients with significant obesity, renal insufficiency, or renoparenchymal disease were excluded from this study. independent visual an ...	2003	430172
radionuclide left ventricular dv/dt for the assessment of cardiac function in patients with coronary disease.	to investigate potential uses of left-ventricular (lv) systolic ejection rate (lv dv/dt) in the evaluation of lv function, we examined the effect of exercise, angiotensin, and leg raising on lv ejection fraction and lv dv/dt in patients with coronary-artery disease. the following observations were made: a) lv ejection fraction and dv/dt changed proportionately, but in opposite directions, during supine exercise; b) lv ejection fraction and dv/dt decreased to a similar extent during angiotensin i ...	2003	430171
neurotensin: antinocisponsive action in rodents.		1979	421735
operation of the coconut fiber/burnt rice husks filter for supplying drinking water to rural communities in southeast asia.		2003	420360
[the value of the lee effect in the rational therapy of juvenile stuttering].		2004	419780
pluridirectional tomography in the evaluation of pituitary tumors.	a series of 110 patients with suspected pituitary tumors was recently evaluated by endocrinologic and neuroradiologic studies. of the 77 patients in this series who underwent surgery, 74 had confirmed pituitary adenomas, two had suprasella tumors of the influndibulum, and one had an empty sella not previously diagnosed at pneumoencephalography. all 17 patients with normal plain skull films but abnormal thin section tomography who underwent surgery had documented pituitary tumors. this includes s ...	1993	413394
the euiryong experiment: a korean innovation in household contraceptive distribution.	although contraceptive practice has increased substantially in korea as a result of a strong national family planning program, surveys indicate the existence of an additional unmet demand. a number of obstacles tend to limit availability of family planning services and supplies. the effects of total availability are being tested in a three-year experiment in household contraceptive distribution, for which an exploratory study was carried out in 1975 in euiryong gun. three distribution systems we ...	2003	403640
lung compliance and lung morphology following artificial ventilation in the premature and full-term rabbit neonate.	rabbit neonates delivered on day 27--30 of gestation were subjected to intermittent positive pressure ventilation (ippv) for 60 min. tidal volume was standardized to 10 ml/kg, and the insufflation pressure required to maintain this tidal volume was recorded. the quasistatic compliance of the lung-thorax system, corrected for variations in body weight, was significantly lower in animals delivered on day 27--28 than in those delivered on day 29--30. immature animals with low lung-thorax complianc ...	1979	394314
specific inhibition of macrophage migration inhibition factor by fucosylated glycolipid rm.	the effects of glycolipids on the interaction of the mif (migration inhibition factor) with rat macrophages were examined using a migration inhibition assay system. mif activity was specifically blocked by fucosylated glycolipid rm [gal alpha 1-3gal(2-1 alpha fuc) beta 1-3galnac beta 1-3gal beta 1-4glc beta 1-1ceramide, (1978) j. biochem. 83, 85-90], but not by cytolipin r, hematoside, or blood group b active glycolipid [gal alpha 1-3gal(2-1 alpha fuc) beta 1-4glcnac beta 1-3gal beta 1-4glc beta ...	1979	389925
site-specific recombination leading to the integration of phages p1 and p7.		1979	385221
[a simple complete cpap (continuous positive airway pressure)-unit for the treatment of respiratory distress syndrome in newborn infants].		2004	373490
effect of early thymectomy on the developing chick embryo [proceedings].		1998	317044
[importance of immunological blood study methods in pregnancy toxicoses for practical public health].		1998	316629
activation of dna metabolism in t-cells by bestatin.		2004	316326
effects of fildes enrichment on antibiotic susceptibility testing of haemophilus influenzae in the autobac.	the results of this investigation showed that the autobac could be used to determine the susceptibility of haemophilus influenzae to ampicillin, chloramphenicol, and tetracycline when eugonic broth was supplemented with 1.5% fildes enrichment. an excellent correlation was obtained between the susceptibilities as determined by the agar dilution minimal inhibitory concentration method and the autobac. for ampicillin all h. influenzae isolates with minimal inhibitory concentrations of </=1 mug/ml h ...	1979	314272
endophthalmitis associated with haemophilus influenzae type b bacteremia and meningitis.	the unusual occurrence of endophthalmitis associated with haemophilus influenzae type b bacteremia and meningitis was confirmed in three young children during a five-year period. in contrast to bacterial endophthalmitis attributed to other microorganisms, these three infections resolved completely within a few days with conventional antimicrobial therapy. endophthalmitis is but one of the apparently increasing number of unsuual complications that may be observed as a result of h influenzae type ...	1979	312601
[alternative for rheumatic patients in yugoslavia].		2001	311082
restimulation of ppd-stimulated lymphocytes: decreased responsiveness of prestimulated cells to a second challenge with ppd and pha.	lymphocytes stimulated with purified protein derivative (ppd) were inhibited in their response to a second stimulation with ppd or phytohaemagglutinin (pha). the degree of inhibition was related to the ppd concentration during prestimulation, the dose-response curve for inhibition resembling very much that of stimulation. the decreased reactivity was neither due to a toxic effect of ppd nor to altered proliferation kinetics of the prestimulated cells. lymphocytes preincubated for 6 h or 16 days ...	2001	311074
[is there a rational basis for the use of a bland diet in the treatment of peptic ulcer?].		2001	311027
association of a b-cell alloantigen with susceptibility to rheumatic fever.		2000	310969
digital e.m.g. processor.		2000	310937
the measurement principle for evaluating the performance of drugs and cosmetics by skin impedance.		2000	310923
[amyloid deposition of the skin lesion in primary systemic amyloidosis, especially amyloid bundle (author's transl)].		2000	310900
secretory granules of the duodenal enterochromaffin cells of the cat.		1979	222959
single-fiber epsps in amphibian motoneurons.		1983	217481
[treatment of african vesico-vaginal fistulae in a rural hospital (author's transl)].	the author reports his own experience of this difficult surgery in a rural african hospital. he describes various types of fistulae and 3 technics which gave him 10 recoveries in 19 patients. complications, rules of treatment and nursing are considered.	1986	214663
effect of interferon on transcription and translation of vesicular stomatitis virus in human and simian cell cultures.	the effect of interferons on vesicular stomatitis virus (vsv) primary transcription, amplified rna synthesis [i.e. the sum of primary transcription rna replication (leading to [ - ] rna) and secondary transcription (leading to [ + ] rna) and virus protein synthesis were studied. in a human cell line, both human and simian interferons inhibited the initiation of primary transcription and amplified rna synthesis. in contrast, in a simian cell line tested similarly, the initiation of these activiti ...	1978	214523
the binding isotherms for the interaction of 5-doxyl stearic acid with bovine and human albumin.	binding isotherms for the interaction of 5-doxyl stearic acid with bovine and human albumin are reported. the critical micelle concentration (cmc) and the limiting solubility of 5-doxyl stearic acid were determined using the electron spin resonance (esr)-spin label method. the cmc and the limiting solubility of this spin-label stearic acid in saline-phosphate buffer are 3.5 x 10(-5) m and 2 x 10(-4) m, respectively. we found no esr line width evidence for pre-association of the spin-label steara ...	1978	213518
central neural pathways for angiotensin-induced thirst.	evidence is reviewed implicating the preoptic region in angiotensin-induced thirst. the most responsive area according to results obtained with behavioral, electrophysiological, and autoradiographic mapping techniques is at the caudal border of the medial preoptic region and rostral border of the anterior hypothalamus. the neural pathway from this preoptic site for angiotensin-induced thirst extends along the medial forebrain bundle through the midlateral hypothalamus to the paramedial midbrain ...	1990	213317
[genetic counseling in defect abnormalities of the extremities (proceedings)].		1986	212892
comparison of interferon action in interferon resistant and sensitive l1210 cells.	translation inhibition, leu-trna aminoacylation and double-stranded rna and atp dependent phosphorylation were examined in interferon-treated and control cell-free lysates of leukaemic mouse l 1210 r and l 1210 s cells. no differences were observed between the respective interferon-treated and control cell-free extracts, except for the presence of an enhanced 67k dalton phosphoprotein fraction in interferon-treated l 1210 s cell-free extracts. in non-responding cell-free lysates, the lack of sti ...	1978	212514
hepatocarcinogens in nigerian foodstuffs.		1987	211740
lecithin: cholesterol acyltransferase activity in patients with chronic liver diseases and positive lp-x tests.	lecithin: cholesterol acyltransferase activity has been measured in serum from patients with various liver disorders and positive lp-x tests and from healthy subjects. statistical analysis indicated that lecithin: cholesterol acyltransferase activity provided no help in the discrimination between the persons of both groups although the mean activities differed significantly.	1989	210070
human beta-endorphin: the real opium of the people?		1978	209845
thermodynamics of binding of oxidized and reduced nicotinamide adenine dinucleotides, adenosine-5'-diphosphoribose, and 5'-iodosalicylate to dehydrogenases.		1990	208598
isolation and characterization of two threonine-poor apolipoproteins of human plasma high density lipoproteins.		1978	208597
[nonexcreting waldenstrom's disease: a further case with anaplastic cancer of the lung and amyloidosis].		1991	208058
synthesis and quantitative structure-activity relationships of antibacterial 1-(substituted benzhydryl)-4-(5-nitro-2-furfurylideneamino) piperazines.	1-benzhydryl -4- (5-nitro-2-furfurylideneamino) piperazine and 11 substituted analogs were prepared and examined for in vitro antimicrobial activity. the compounds were active against bacillus cereus 7, bacillus megaterium 122, bacillus subtilis 104, clostridium perfringens 13, and the tetracycline-resistant clostridium perfringens 37. regression analyses on the antibacterial activity data based on the hansch approach, using pi, pi2, and sigma parameters, yielded several statistically significan ...	1978	207855
cytochrome c from schizosaccharomyces pombe. 2. amino-acid sequence.	the amino acid sequence of schizosaccharomyces pombe cytochrome c has been established by automatic degradation of the protein and by manual degradation of fragments obtained by cyanogen bromide cleavage and chymotryptic digestion. the chymotryptic peptides were aligned by homology with other known cytochrome c sequences. the protein is 108 residues long, with a four-residue amino-terminal tail. it has only one methionine residue and differs from other fungal cytochromes c in lacking the one-res ...	1992	207525
the effects of nerve growth factor and its antiserum on synapses in the superior cervical ganglion of the guinea-pig.	1. the effects of nerve growth factor (ngf) and its antiserum on synapses in the superior cervical ganglion of the guinea-pig have been examined by intracellular recording and electron microscopy. 2. exogenous ngf, supplied locally from a silicone rubber pellet implanted near ganglia for 4-7 days, had little effect on either the function or the number of ganglionic synapses. 3. however, the depression of synaptic transmission and loss of synaptic contacts on ganglion cells which follow post-gang ...	1978	206691
effect of treatment with exogenous interferon, polyriboinosinic-polyribocytidylic acid, or polyriboinosinic-polyribocytidylic acid-poly-l-lysine complex on herpesvirus hominis infections in mice.	the effect of treatment with exogenous interferon was compared with those of two interferon inducers, polyriboinosinic-polyribocytidylic acid [poly(i) . poly(c)] and poly(i) . poly(c)-poly-l-lysine complex [poly(iclc)], in three model herpesvirus hominis type 2 infections of mice. after intraperitoneal inoculation of h. hominis type 2, all drugs significantly protected animals against death and increased the mean day of death when administered as late as 48 hr after viral inoculation. with intra ...	1978	206632
hepatitis a.		1977	205765
investigation on the kinetic mechanism of octopine dehydrogenase. a regulatory behavior.	the kinetic scheme of octopine dehydrogenase of pecten maximus l., a monomeric enzyme obeying a bi-ter sequential mechanism, was completed, essentially in the forward reaction, by steady-state studies over a wide range of substrate concentration at ph 7.0. deviation from the michaelis-menten behavior with respect to nad+ and other significant kinetic data led us to ascribe for octopine dehydrogenase mechanism the mnemonical enzyme concept. in addition, another regulatory behavior can be envisage ...	1994	205413
intratumor chemoimmunotherapy with mitomycin c and components from mycobacteria in regression of line 10 tumors in guinea pigs.	intratumor chemotherapy with the use of mitomycin c and/or immunotherapy caused regression of line 10 carcinomas in strain 2 guinea pigs and resulted in development of tumor-specific immunity. the immunotherapeutic preparation consisted of oil-in-water emulsions containing mycobacterium cell walls or residues of cell walls termed cell wall skeletons. the latter preparations were combined with trehalose dimycolate, which was isolated by microparticulate chromatography from whole cells of mycobact ...	1978	205361
necrotizing pancreatitis due to simian adenovirus type 31 in a rhesus monkey.	simian adenovirus type 31 was isolated from pancreatic tissue of an 8-year-old male rhesus monkey that died as the result of acute necrotizing pancreatitis. histologically, the pancreas showed wide-spread necrosis, extensive infiltration of polymorphonuclear leukocytes, and nuclear inclusions in pancreatic acinar cells. large numbers of adenovirus particles were demonstrable in the acinar cells by electron microscopy. this is the second case of adenovirus-associated pancreatitis we have found in ...	1978	205187
[prostaglandins and bronchial asthma (author's transl)].	prostaglandins (pg) show different effects on the bronchomotoric excitability depending on the fact to which group they certain. the best investigated pg are pge1, pge2 (bronchodilators) and pgf2a (bronchoconstrictor). it is possible that pg play a certain role in the pathogenesis of bronchial asthma. among other hypotheses, the influence upon adenylate cyclase - camp systems (without affecting the adrenoreceptors) is evident. probably, pg exert a regulatory function on bronchial tone. the patho ...	1994	205127
[histology, fine structure and differentiation of experimental wilms tumors (author's transl)].	histologic studies indicate that the cycasin-induced wilms' tumor in the rat is equal to human nephroblastoma in appearance. therefore, it may represent an interesting system for experimental oncology. in electron microscopy, the spindle cells of the sarcoma region mostly represent tubular cells. besides, the author's results showed that preexisting mesenchyma cells and blood vessels also form part of the tumor. electron microscopy studies have shown that cycasin feeding will lead to early cellu ...	1978	204826
respiratory disease in horses.		1977	196170
[determination of serum acth].		2002	186651
[distribution and activity of pyridoxal kinase in human brain during ontogenesis].	the activity of pyridoxal kinase was sharply increased in whole brain tissue of human, embryos and fetuses within 6-11 weeks of development. in brain stem the maximal values of the enzyme activity was observed at early stages of prenatal development of fetuses. the activity of pyridoxal kinase was increased in cerebral cortex and in the limbic system up to complete maturation of fetuses. it correlated with the fetus age within 14-40 weeks of development as calculated per 1 g of tissue wight or 1 ...	1976	179608
[study of c1. perfringens resistance to lincomycin].	a possibility of developing resistant forms of c1. perfringens during treatment of experimental anaerobic (gaseous) infection with lincomycin was studied. it was shown that treatment of the animals for 7 days resulted in an increase in the resistance by 33-41 times. it was noted that strains with decreased sensitivity to lincomycins had changed morphology and biochemical activity (decreased lecitinase activity, changed biochemical properties), decreased virulence and pathogenicity for animals. s ...	1976	179463
[sensitivity of various races of the tularemia microbe to erythromycin, oleandomycin and polymyxin].	sensitivity of 66 strains of the tularemia microbe to erythromycin, oleandomycin and polymyxin was studied. it was shown that all the strains were resistant to polymyxin. the strains of the non-artic and central asiatic races and 64 per cent of the strains of the holarctic race were resistant to erythromycin and oleandomycin.	1976	179462