Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
|---|
| update of lomefloxacin in vitro activity and spectrum. a multicenter trial testing contemporary pathogens following food and drug administration validation guidelines. lomefloxacin activity study group. | the united states food and drug administration recently recommended that the antimicrobial product package insert (ppi) subsection on microbiology be annually validated with regard to the compound's spectrum and potency. to address this request, a nine-laboratory trial was organized to test (two methods) lomefloxacin, a newer fluoroquinolone, and nine comparison drugs against ppi-listed pathogens (1934 strains). a broad geographic sampling (nine medical centers) was achieved, and lomefloxacin wa ... | 1994 | 7867311 |
| cefquinome (hr 111v). in vitro evaluation of a broad-spectrum cephalosporin indicated for infections in animals. | cefquinome (formerly hr 111v), an aminothiazolyl cephalosporin, was compared with cefepime, cefpirome, cefotaxime, and ceftazidime against 681 clinical cultures and a challenge set of bacteria with well-characterized resistance mechanisms. cefquinome minimum inhibitory concentrations (mic90) for the enterobacteriaceae ranged from < or = 0.12-2 micrograms/ml with the highest mic (4 micrograms/ml) obtained among citrobacter freundii, enterobacter cloacae, and providencia stuartii strains. a total ... | 1994 | 7867299 |
| comparative in vitro activity of fk-037, a new cephalosporin antibiotic. | the in vitro activity of fk-037, a novel parenteral oxime-type cephalosporin, was compared with that of cefepime, cefpirome, ceftazidime, imipenem, and gentamicin against a total of 668 recent clinical isolates. minimum inhibitory concentrations were determined by a standard agar dilution procedure, and all isolates were tested at two inocula (10(4) and 10(6) colony forming units). fk-037 inhibited 90% of isolates of escherichia coli, klebsiella species, proteus mirabilis, p. vulgaris, morganell ... | 1994 | 7867295 |
| in vitro activity of subinhibitory concentrations of quinolones on urea-splitting bacteria: effect on urease activity and on cell surface hydrophobicity. | the effect of subinhibitory concentrations of ciprofloxacin, lomefloxacin, norfloxacin, ofloxacin, and sparfloxacin on urease activity and on cell surface hydrophobicity of urea-splitting bacteria was examined. quinolones at 0.5 mics demonstrated variable effects on bacterial-urease activity. norfloxacin inhibited enzyme activity in proteus vulgaris and proteus mirabilis, while other quinolones had no effects. in morganella morganii, sparfloxacin and ciprofloxacin enhanced urease activity, parti ... | 1995 | 7844396 |
| enteropathogens associated with acute diarrhoeal diseases. | five types of escherichia coli are responsible for as much as 25% of all diarrheal diseases in developing countries. they tend to be transmitted via contaminated foods, particularly weaning foods, and water. they include enterotoxigenic, enteropathogenic, enteroadherent, enteroinvasive, and enterohemorrhagic e. coli. shigella species are responsible for 10-15% of acute diarrheas in children less than 5 years old and the most common etiologic agents of childhood dysentery. shigellosis is common i ... | 1994 | 7835992 |
| [current status of resistance of bacteria to pefloxacin in hospital units. cross resistance with ofloxacin and ciprofloxacin. results of a multicenter study]. | the antibacterial activities of pefloxacin (pef), ofloxacin (ofl), ciprofloxacin (cip) were measured by agar diffusion (5 micrograms strength disks) against 6370 non duplicate clinical isolates collected in november 1991 in 40 hospitals from various areas in france. the mics of pef, ofl and cip were determined by agar dilution against intermediate or resistant strains to one of the three antibiotics (inhibition zone < 16 mm for pef, ofl, < 19 mm for cip). in the enterobacteriaceae the overall in ... | 1994 | 7824298 |
| isolation of three hexahydro-1,3,5-trinitro-1,3,5-triazine-degrading species of the family enterobacteriaceae from nitramine explosive-contaminated soil. | three species of the family enterobacteriaceae that biochemically reduced hexahydro-1,3,5-trinitro-1,3,5-triazine (rdx) and octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazocine (hmx) were isolated from nitramine explosive-contaminated soil. two isolates, identified as morganella morganii and providencia rettgeri, completely transformed both rdx and the nitroso-rdx reduction intermediates. the third isolate, identified as citrobacter freundii, partially transformed rdx and generated high concentratio ... | 1994 | 7811097 |
| in vitro antibacterial activity and beta-lactamase stability of sy5555, a new oral penem antibiotic. | the antibacterial activity of sy5555, a new oral penem antibiotic, was compared with those of cefaclor, cefixime, and cefteram. sy5555 was more active than the comparison agents against methicillin-susceptible staphylococcus aureus, staphylococcus epidermidis, streptococcus pneumoniae, enterococcus faecalis, citrobacter freundii, enterobacter cloacae, morganella morganii, acinetobacter calcoaceticus, clostridium spp., and bacteroides fragilis. against providencia spp., proteus spp., and haemophi ... | 1994 | 7811005 |
| purification and preliminary crystallographic studies of penicillin g acylase from providencia rettgeri. | two isoforms of the heterodimeric enzyme penicillin g acylase (ec 3.5.1.11) from providencia rettgeri atcc 31052 (strain bro1) were purified to near homogeneity. the isoforms exhibited comparable enzymatic activities but differed slightly in the molecular weight and pi of their respective alpha-subunit. the origin of this difference was traced to the partial conversion of the n-terminal gln of the alpha-subunit to pyrrolidonecarboxylic acid (pyro-glu). the boundaries of the mature enzyme within ... | 1995 | 7795527 |
| multicenter in vitro comparative study of fluoroquinolones against 25,129 gram-positive and gram-negative clinical isolates. | in vitro activities of fleroxacin, ciprofloxacin, ofloxacin, and lomefloxacin were evaluated against 25,129 fresh bacterial isolates from 51 us hospital or medical center laboratories, beginning in october of 1990. susceptibility rates were > or = 85% against most species of gram-negative bacteria. notable exceptions were pseudomonas, acinetobacter, xanthomonas, and providencia. the study drugs displayed similar activity against most gram-negative species. at least 90% of oxacillin-susceptible s ... | 1995 | 7789095 |
| identification and analysis of aarp, a transcriptional activator of the 2'-n-acetyltransferase in providencia stuartii. | the aarp gene has been identified in a search for activators of the 2-n-acetyltransferase [encoded by aac(2')-ia] in providencia stuartii. introduction of aarp into p. stuartii on a multicopy plasmid resulted in a 9.9-fold increase in the accumulation of beta-galactosidase from an aac(2')-lacz fusion. northern (rna) blot analysis demonstrated that this increased aac(2')-ia expression occurred at the level of mrna accumulation. the deduced aarp protein was 15,898 da in size and exhibited signific ... | 1995 | 7768849 |
| [evaluation of a system of multimicrotests for biochemical identification of enterobacteria (mmt e2) in a controlled epidemiological trial. 2]. | commercial system of multimicrotests for biochemical identification of enterobacteria mmt e2 and routine tube tests were compared in a controlled epidemiologic experiment with 205 enterobacterial strains. the system has been developed at the allergen research and production amalgamation. system mmt e2 fairly well met the requirements to diagnostic preparations of this kind; its results were compatible and well reproducible. this system in complex with commercial mmt e1 system may be used for spe ... | 1995 | 7757370 |
| effect of salicylate on expression of flagella by escherichia coli and proteus, providencia, and pseudomonas spp. | osmotic stress, salicylate, and mar (multiple antibiotic resistance) mutation are known to block the expression of the ompf porin. since these conditions have also been shown to inhibit the expression of p and cfa fimbriae in escherichia coli, we speculated that they might affect the expression of flagella as well. hyperosmotic conditions have been shown to block the synthesis of flagellin and expression of flagella in e. coli (c. li, c. j. louise, w. shi, and j. adler, j. bacteriol. 175:2229-22 ... | 1995 | 7729888 |
| e-4695, a new c-7 azetidinyl fluoronaphthyridine with enhanced activity against gram-positive and anaerobic pathogens. | e-4695, (-)-7-[3-(r)-amino-2-(s)-methyl-1-azetidinyl]-1-cyclopropyl-1,4- dihydro-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid, is a new fluorinated naphthyridine with an azetidine moiety. the mics of e-4695 at which 90% of the isolates were inhibited (mic90s) were 0.06 to 0.5 microgram/ml for gram-positive cocci, including species of the genera staphylococcus, streptococcus, and enterococcus, and the mic90s against gram-negative pathogens such as members of the family enterobacteriaceae (w ... | 1995 | 7726507 |
| proteus mirabilis urease: transcriptional regulation by urer. | proteus mirabilis urease catalyzes the hydrolysis of urea, initiating the formation of urinary stones. the enzyme is critical for kidney colonization and the development of acute pyelonephritis. urease is induced by urea and is not controlled by the nitrogen regulatory system (ntr) or catabolite repression. purified whole-cell rna from induced and uninduced cultures of p. mirabilis and escherichia coli harboring cloned urease sequences was probed with a 4.2-kb bgli fragment from within the ureas ... | 1993 | 7678244 |
| cloning of the mgte mg2+ transporter from providencia stuartii and the distribution of mgte in gram-negative and gram-positive bacteria. | the mm281 strain of salmonella typhimurium possesses mutations in each of its three mg2+ transport systems, requires 100 mm mg2+ for growth, and was used to screen a genomic library from the gram-negative bacterium providencia stuartii for clones that could restore the ability to grow without mg2+ supplementation. the clones obtained also conferred sensitivity to co2+, a phenotype similar to that seen with the s. typhimurium cora mg2+ transport gene. the sequence of the cloned p. stuartii dna re ... | 1995 | 7665526 |
| bactericidal activity of normal human serum against morganella, proteus, and providencia strains. | the susceptibility od proteus, providencia, and morganella strains to bactericidal action of human serum was examined. the percentage of survival was determined after one and three hours incubation with 50% human serum. the susceptible strains were treated by serum preparations with blocked classical or alternative complement activation pathways as well as with lysozyme removed. following mechanisms of the bactericidal action of serum were found: complement activated by the classical or alternat ... | 1995 | 7660859 |
| laboratory data which differentiate meropenem and imipenem. | meropenem and imipenem are carbapenems which are distinguishable from all other currently available beta-lactam antibiotics by breadth of antibacterial spectrum and stability to beta-lactamases, but can be differentiated one from another. meropenem is relatively stable to human renal dehydropeptidase-i (dhp-i); it does not require to be co-administered with cilastatin and consequently, unlike imipenem, will be administered as a single agent. in vitro both meropenem and imipenem are active agains ... | 1995 | 7652504 |
| contribution of gentamicin 2'-n-acetyltransferase to the o acetylation of peptidoglycan in providencia stuartii. | a collection of providencia stuartii mutants which either underexpress or overexpress aac(2')-ia, the chromosomal gene coding for gentamicin 2'-n-acetyltransferase (ec 2.3.1.59), have been characterized phenotypically as possessing either lower or higher levels of peptidoglycan o acetylation, respectively, than the wild type. these mutants were subjected to both negative-staining and thin-section electron microscopy. p. stuartii pr100, with 42% o acetylation of peptidoglycan compared with 52% o ... | 1995 | 7635816 |
| urinary bacteriology of continent urinary reservoirs and calculus formation. | in order to investigate urinary bacteriology in relation to calculus formation in continent urinary reservoirs, a retrospective study was conducted of 19 patients with the kock pouch and 23 patients with the indiana pouch. analysis of a total of 151 urine cultures showed that asymptomatic bacteria (any bacterial count) were present in 92% of urines from the kock pouch and 74% from the indiana pouch. the incidence of organisms and total bacterial counts were similar for both pouches. the most pre ... | 1994 | 7614396 |
| a new plasmid cloning vector for direct detection of recombinant clones, based on inactivation of a bacterial acid phosphatase-encoding gene. | a new plasmid cloning vector for escherichia coli (pphor) suitable for direct detection of recombinant clones has been constructed. the plasmid is a multicopy of a vector which carries a puc-derived origin of replication and beta-lactamase gene, and the phon acid phosphatase-encoding gene from providencia stuartii. foreign dna fragments can be cloned into unique restriction sites located within the phon gene causing a loss of the acid phosphatase activity which is normally overproduced by e. col ... | 1995 | 7603348 |
| engineering human monoclonal antibody fragments: a recombinant enzyme-linked fab. | a new plasmid vector, pcrp, allowing the expression of human recombinant monoclonal antibody fab fragments fused with a bacterial acid phosphatase has been constructed. pcrp can accept heavy- and light-chain cdnas cloned from combinatorial antibody libraries displayed on filamentous phages with the pcombiii system and is able to direct expression to soluble fabs in which the carboxy-terminus of the heavy chain is fused to the amino-terminus of the mature phon nonspecific acid phosphatase of prov ... | 1995 | 7603339 |
| proteus mirabilis amino acid deaminase: cloning, nucleotide sequence, and characterization of aad. | proteus, providencia, and morganella species produce deaminases that generate alpha-keto acids from amino acids. the alpha-keto acid products are detected by the formation of colored iron complexes, raising the possibility that the enzyme functions to secure iron for these species, which do not produce traditional siderophores. a gene encoding an amino acid deaminase of uropathogenic proteus mirabilis was identified by screening a genomic library hosted in escherichia coli dh5 alpha for amino ac ... | 1995 | 7592338 |
| the role of cefotaxime in the treatment of surgical infections. | this study examines the role of cefotaxime in the treatment of both gram-negative and gram-positive surgical infections. a dose of 2 g of cefotaxime will sustain peripheral compartment concentrations of 2.6, 3.9, 1.6, and 0.7 micrograms/ml for 6, 8, 10 and 12 h, respectively. therefore, the proportion of pathogens with a minimal inhibitory concentration (mic) below the peripheral compartment cefotaxime concentrations was assessed as a measure of therapeutic potential. it was observed that bacter ... | 1995 | 7587036 |
| loss of porins following carbapenem-resistance selection and adherence modification in enterobacteria. | the acquired resistance to the carbapenems is frequently joined to modified expression of porins or other outer membrane (om) structures, thus bacterial adherence, that also depends on the presence of peculiar surface structures, might theoretically be influenced. in this study the ability to adhere to hep-2 and i-407 eukaryotic cell monolayers was assayed for two susceptible strains of serratia marcescens, one strain of enterobacter cloacae and one of providencia rettgeri in comparison with tha ... | 1995 | 7562008 |
| bacterial agents causing chronic suppurative otitis media. | ear swabs from 350 patients with chronic otitis media attending different orthorhinolaryngological clinics at different hospitals and health centres in benin city and ekpoma in edo state were screened for the presence of bacterial agents of chronic otitis media. results revealed the presence of 19 different species indicating polymicrobial infections. species isolated comprised staphylococcus aureus (33.6%), pseudomonas aeruginosa (19.3%), proteus mirabilis (17%), alcaligenes faecalis (6.2%) and ... | 1995 | 7498006 |
| [epidemiological studies of increasing appearances of proteus inconstans (providencia stuartii) infections (author's transl)]. | since proteus inconstans turns out to be the causative agent of an increasing amount of hospital infections, studies on this species are necessary. by means of bacteriocines, biochemical reactions and antibiograms 53 strains were subclassified. 47 strains displayed same biochemical properties, 44 strains showed the same antibiogram. by the method on the basis of bacteriocine typing 15 groups were established. the strains with the same biochemical properties and the same antibiograms could be fur ... | 1980 | 7461700 |
| comparative antimicrobial activity of o-demethylfortimicin a, a derivative of fortimicin a. | the in vitro antimicrobial activity of o-demethylfortimicin a (odmf), a derivative of fortimicin a, was compared with those of fortimicin a and gentamicin against a spectrum of 256 organisms. all three antibiotics were active in low concentrations against all strains of enterobacteriaceae, acinetobacter sp., and staphylococcus aureus, with odmf most active against proteus mirabilis, indole-positive proteus, and providencia and gentamicin most active against other species. activity of each of the ... | 1980 | 7447430 |
| [enterobacteria of bats (chiroptera) (author's transl)]. | the aerobic gram-negative faecal flora of 38 bats consisting of 10 species and genera respectively, of microchiroptera, and of 4 species and genera respectively, of megachiroptera was studied (table 1 and 3). there were no specific differences between insectivora and frugivora: e. coli 15-24%, citrobacter 8-10%, enterobacter-klebsiella-group 40-43% and proteus-group 28-30% (table 2). the overwhelming majority of the isolated bacteria were lactose-positive (table 3), corresponding to the membersh ... | 1980 | 7424248 |
| [serotyping of bacteria of the genus providencia using the indirect hemagglutination test and the indirect hemagglutination inhibition test]. | the experiments with the collection of strains and diagnostic sera available in the ussr confirmed the data contained in the literature on the good prospects of using the indirect hemagglutination test for the serotyping of bacteria belonging to the genus providencia. certain differences were observed in cross reactions, revealed by the indirect hemagglutination test and by agglutination: the interrelations of serogroups o14 and o25, o23 and o25, o23 and o29, o29 and o45, o37 and o49, determined ... | 1980 | 7415677 |
| nosocomial multiply resistant providencia stuartii: a long-term outbreak with multiple biotypes and serotypes at one hospital. | a long-term outbreak of urinary tract-associated multiply resistant providencia stuartii occurred in a large medical facility that included a 513-bed chronic care unit. the unique characteristics of this outbreak were that from within a single medical facility, p. stuartii with multiple serotypes, biotypes, and antibiograms could be identified. the organisms isolated had five different biotypes, seven different antibiograms, and two major serotypes. all of the organisms were susceptible to amika ... | 1980 | 7358840 |
| renal pathology of catheterized baboons (papio cynocephalus). | renal disease was found at necropsy in 27 of 60 catheterized baboons (papio cynocephalus). primary diagnoses were infarcts in eight baboons, septic embolic nephritis in four, and mesangioproliferative glomerulonephritis in 15. infarcts and septic embolic nephritis are multifocal renal diseases; mesangioproliferative glomerulonephritis is diffuse, progressive and often accompanied by severe proteinuria, hypoalbuminemia (less than 3 g/dl), and generalized edema. five of the 15 baboons with glomeru ... | 1981 | 7344248 |
| patterns of oral bacterial infection in captive snakes. | the bacterial isolates from culture specimens of snakes with infectious stomatitis were compared with those from culture specimens of the oral cavity of healthy captive snakes. cloacal swab specimens were also taken from healthy snakes to compare their intestinal and oral bacterial populations. the healthy snakes had a predominantly gram-positive oral flora, with corynebacterium spp and coagulase-negative staphylococcus spp being the organisms isolated most frequently. the specimens from snakes ... | 1981 | 7328007 |
| examination of major disagreements in susceptibility test results by autobac-1 and ms-2. | major disagreements between two automated susceptibility test instruments, autobac-1 and ms-2, generated from 4,213 tests on 630 bacterial isolates, were analyzed. the major disagreement rate between the instruments was only 7.4%. the highest major disagreement rates for bacteria were with staphylococcus epidermidis, enterococci, gram-positive bacilli, and providencia species, and those for antibiotics were with ampicillin and penicillin g. with most other bacteria and antibiotics, the instrumen ... | 1981 | 7283410 |
| [errors in the bacteriologic diagnosis of dysentery and ways of eliminating them]. | the study of 1023 strains, formerly identified as shigella, has revealed that 67 of these strains belong to escherichia, enterobacter, klebsiella, providencia, pseudomonas, flavobacterium. such errors are due to the insufficient use of biochemical tests in the process of identification. to improve shigella identification, after the evaluation of changes in olkenitsky's medium of trisaccharide agar the tests for urease activity, citrate and acetate assimilation, lysine decarboxylase, mobility at ... | 1981 | 7269916 |
| antibiotic resistance in providencia stuartii isolated in hospitals. | a total of 238 isolates of providencia stuartii obtained from infected patients in six dublin hospitals were grouped by using serological and bacteriocin typing methods and tested for sensitivity to a number of antimicrobial agents. most isolates were resistant to several of these agents. resistance to tetracycline, resistance to penicillin, resistance to polymyxin, and probably resistance to nitrofurantoin was intrinsic. plasmid screening coupled with resistance transfer studies showed that bot ... | 1981 | 7251830 |
| [incidence and antibiotic-sensitivity of gram-negative bacteria in the urinary infections (author's transl)]. | urinary tract infections due to low-grade pathogenic gram-negative bacteria show an increasing prevalence. the frequency of isolation from urinary samples of some of these pathogens (alcaligenes, citrobacter, acinetobacter, providencia, serratia) was detected in a group of adult patients. the role of local and systemic predisposing factors was investigated. these bacterial agents accounted for 21% of 1,354 isolated strains. systemic predisposing factors were found in most patients. moreover, a h ... | 1980 | 7244101 |
| transferable urease activity in providencia stuartii. | six urea-positive providencia stuartii strains were tested for transmissible urease determinants. two strains, when implanted with "helper" conjugative plasmids, were found to be capable of transferring urease genes to escherichia coli or urea-negative p. stuartii. recombination of the urease genes with the helper plasmid in p. stuartii was noted in one case. one of the urea-positive p. staurtii strains was found to harbor a conjugative plasmid which mediated both urease activity and ampicillin ... | 1981 | 7240389 |
| differences among providencia species in their in vitro susceptibilities to five antibiotics. | significant differences among the three providencia species (p. alcalifaciens, p. stuartii, and p. rettgeri) in antimicrobial susceptibilities to five antibiotics were shown. p. stuartii was the most resistant of the three species, and p. alcalifaciens was the most susceptible. p. rettgeri was similar to p. stuartii in susceptibilities to cefoxitin, cephalothin, and cefamandole but differed in showing greater susceptibilities to tobramycin and gentamicin. cefoxitin (16 micrograms/ml) and cefaman ... | 1980 | 7235674 |
| [utilization and fermentation of 2-ketogluconate by "enterobacteriaceae" (author's transl)]. | two methods were compared: 1) the ability to use 2-ketogluconate (2-kg) as source of carbon and energy in defined medium, and 2) the ability to produce acid by fermentation of 2-kg (0.5 g/100 ml) in peptone water with phenol red. results of growth on, and acid production from, 2-kg were identical. a total of 990 strains was studied. no strain of escherichia coli, shigella (4 species), salmonella (4 sub-genera), yersinia pestis, y. pseudotuberculosis, edwardsiella (2 species), proteus vulgaris, p ... | 1981 | 7235456 |
| three episodes of nosocomial urinary tract infections caused by one o-serotype of providencia stuartii. | the results of o-serotyping providencia stuartii isolates in a general hospital showed that 43 isolates were the same serotype (063) and were from 15 patients located in 1 or 2 adjacent wards. on retrospective examination it was found that the series of infections occurred during a 9-month period and could be separated into 3 episodes, involving 7, 6 and 2 patients. all patients who acquired the providencia stuartii 063 strain were catheterized. the introduction of the strain into the hospital w ... | 1981 | 7230337 |
| antiseptic and antibiotic resistance in gram-negative bacteria causing urinary tract infection in spinal cord injured patients. | fifty-seven isolates of gram-negative bacterial species from urinary tract infections in spinal cord injured patients were tested for their sensitivity to chlorhexidine, cetrimide, glutaraldehyde, phenyl mercuric nitrate (pmn), a phenolic disinfectant (hycolin) and a proprietary antiseptic containing a mixture of picloxydine, octylphenoxypolyethoxyethanol and benzalkonium chloride (resiguard). none of the isolates were resistant to glutaraldehyde, hycolin or pmn but a substantial percentage were ... | 1981 | 7220061 |
| an outbreak of providencia stuartii urinary tract infections. patients with condom catheters are a reservoir of the bacteria. | we investigated an outbreak of multiple antibiotic-resistant providencia stuartii urinary tract infections that occurred on a neurology ward. only patients who had been catheterized became infected. however, approximately 10% of patients with condom catheter urinary drainage systems were colonized, ie, p stuartii was present on their skin and in the urine drainage bags but not in fresh-voided urine. patient urinals were also contaminated. the outbreak was terminated by segregating infected and c ... | 1981 | 7206165 |
| a numerical taxonomic study of the genus shigella. | one hundred and two strains representing four species of the genus shigella and sixty-four strains representing fourteen other genera of the family enterobacteriaceae were tested for 192 characters based on their morphology, biochemistry and physiology. the data were subjected to a number of numerical analyses. the results (confirmed by the use of overlap statistics) showed that four phenons can be distinguished within the genus shigella. these correspond with the species s. dysenteriae. s. flex ... | 1982 | 7175494 |
| [antibiograms in ambulatory medical practice. results with a group of gram-negative bacilli strains isolated by uroculture]. | during the april 1979--june 1978 period, 1161 tests were carried out on the sensitivity to antibiotics and chemotherapeutical agents of gram-negative bacillus strains isolated from 7632 urocultures. resistance was tested under qualitative control against 13 antimicrobial agents by the kirby-bauer diffusimetric method. the resistance sensitivity and the presence of intermediary strains is shown for e. coli citrobacter, enterobacter, klebsiella, proteus, morganella, providencia, and pseudomonas. a ... | 1982 | 7156696 |
| prospective survey of fecal, urinary tract, and environmental colonization by providencia stuartii in two geriatric wards. | a prospective survey of fecal, urinary tract, and environmental colonization by providencia stuartii in two wards was undertaken over a 5-month period. eight of 53 male patients and 2 of 89 female patients were colonized with the endemic serotype o:63. two patterns of colonization were found on the male ward. two patients had persistent urinary tract colonization with no detectable fecal carriage. the other patients had fecal carriage, in some cases persistent, with intermittent urinary tract co ... | 1982 | 7130358 |
| innate human serum bactericidal activity against salmonella, shigella, citrobacter and providencia sp. | 1982 | 7121140 | |
| comparison of three automated systems for antimicrobial susceptibility testing of gram-negative bacilli. | several instruments for automated or semiautomated susceptibility testing are currently available. three of these instruments, autobac (general diagnostics, warner-lambert co., morris plains, n.j.), ms-2 (abbott laboratories, dallas, tex.), and automicrobic system (ams) (vitek, inc., hazelwood, mo.) were compared for antimicrobial susceptibility testing of gram-negative bacilli. a total of 207 isolates representing 29 species of gram-negative bacilli were tested simultaneously by each instrument ... | 1982 | 7096560 |
| [characteristics of the fatty acid composition of providencia alcalifaciens and providencia stuartii lipids]. | the fatty acid composition of total cellular lipids and lipid a of lipopolysaccharides was studied in providencia alcalifaciens and p. stuartii. significant differences were found in the fatty acid composition of total cellular lipids from the above species; these are caused mainly by the presence of cyclopropane fatty acids (methylenehexadecanoic and methyleneoctadecanoic acids) in p. stuartii and their absence in p. alcalifaciens. differences were also established in the content of fatty acids ... | 1982 | 7070309 |
| [effectiveness of the combined use of tobramycin with carbenicillin or cephalosporins in experimental infection in mice caused by providencia stuartii]. | antibacterial activity of tobramycin in combination with carbenicillin or cephalosporins against 20 strains of providencia stuartii was studied. the combinations of tobramycin with carbenicillin (1 : 2.5) or cephaloridine (1 : 1) were most active. the mic of tobramycin used in combination with carbenicillin or cephaloridine decreased 3-30 times. in treatment of albino mice with sepsis caused by providencia stuartii it was possible to lower 2-8 times the dose of tobramycin used in combination wit ... | 1982 | 7065647 |
| comparison of two methods for same-day identification of enterobacteriaceae. | two commercial methods, api 20e (as modified for same-day enterobacterial identification) and micro-id, were evaluated for ability to provide useful same-day information of 368 clinically isolated enterobacteriaceae. organisms included escherichia coli (54), shigella (7), edwardsiella tarda (1), salmonella enteritidis (10), citrobacter (30), klebsiella (55), enterobacter (68), hafnia alvei (2), serratia (33), proteus (64), morganella morganii (24), providencia (18), and yersinia enterocolitica ( ... | 1982 | 7051807 |
| [taxonomic problems of bacteria in the genera rettgerella and providencia]. | 1982 | 7043965 | |
| spot indole test: evaluation of four reagents. | kovacs indole reagent, p-dimethylaminobenzaldehyde, ehrlich indole reagent and p-dimethylaminocinnamaldehyde were used as spot indole reagents to test 359 strains of gram-negative rods growing on 5% sheep blood agar, trypticase soy agar (bbl microbiology systems), and macconkey agar. the p-dimethylaminocinnamaldehyde reagent was the most sensitive of those tested and provided results that were easiest to interpret. the p-dimethylaminocinnamaldehyde reagent was able to detect providencia alcalifa ... | 1982 | 7040458 |
| [quantitative bacterial ecology of normal nasal mucosa]. | a quantitative research into the aerobic bacteria of human nasal cavities has been carried out; 183 healthy individuals observed, negative results 18 (9.83%). streptococcus, enterococcus, staphylococcus aureus, staphylococcus epidermidis, micrococcus, streptococcus pneumoniae, neisseria, were numerically determined and the incidence of each single species or genus exactly specified. among gram-negative bacteria, enterobacter, providencia, proteus, citrobacter freundii, haemophilus influenzae, kl ... | 1981 | 7034653 |
| selective medium for isolation of klebsiella pneumoniae. | selective media for klebsiella pneumoniae have been important in studies of hospital-acquired infections. on an agar medium which included ornithine, raffinose, and koser citrate, k. pneumoniae strains grew as yellow mucoid colonies at 24 h and there was some increase in colony size at 48 h. other members of enterobacteriaceae were inhibited or produced small pink colonies on this same medium. pseudomonas, providencia, acinetobacter, and proteus species did not grow or showed very poor growth. t ... | 1981 | 7019238 |
| enterotoxigenic bacteria in food and water from an ethiopian community. | food and water samples from an ethiopian community were screened for the presence of enterotoxin-producing bacteria. using the chinese hamster ovary cell assay, 40 of 213 isolates (18.8%) produced heat-labile (lt) enterotoxin. these lt-producing isolates comprised 33 of 177 (18.6%) strains from 24 of 68 food samples (35.3%) and 7 of 36 (19.4%) isolates of 4 of 17 water samples (23.5%). one lt-producing strain each of salmonella emek and of shigella dysenteriae was found. three pseudomonads, all ... | 1981 | 7016032 |
| acquired cross resistance to aminoglycosides in gentamicin-sensitive and gentamicin-resistant strains of enterobacteria. | the development of non-specific resistance ot gentamicin, tobramycin and amikacin was studied in 12 clinical isolates of enterobacteria with various patterns of aminoglycoside resistance. strains were characterised with respect to mic, transferability of resistance and possession of acetylating and adenylylating enzymes. an increase in aminoglycoside resistance was induced in 10 strains by a single exposure to the concentration of gentamicin, tobramycin or amikacin immediately below the mic. suc ... | 1981 | 7014903 |
| predictability of methenamine efficacy based on type of urinary pathogen and ph. | this study involved 27 geriatric patients with asymptomatic chronic bacteriuria; all had indwelling foley catheters. the treatment regimens (daily oral dosage) were: methenamine mandelate (mm) granules, 4 gm; mm, 4 gm, plus ascorbic acid, 4 gm; and mm, 4 gm, plus ascorbic acid, 4 gm, plus cranberry cocktail, 1 liter--administered according to a cross-over design. proteus vulgaris, pseudomonas aeruginosa and e. coli were the most common urinary organisms. proteus organisms were more often found i ... | 1981 | 7014695 |
| genetic recombination between proteus mirabilis and providencia alcalifaciens. | chromosome transfer occurred in plate matings between proteus mirabilis strain pm5006 and providencia alcalifaciens strain p29 in either direction with the use of plasmid d or r772 as sex factor. auxotrophic chromosomal markers of recipients were converted to prototrophy and the galactose fermentation marker of donor pm5006 could also be selected. recombination frequencies for a group of selected markers in pm5006(d) x p29 matings varied between 3 x 10(-5) (trp+) and 1.2 x 10(-7) (lys+) per dono ... | 1980 | 7012276 |
| evaluation of the repliscan system for enterobacteriaceae identification. | a total of 1,013 isolates of enterobacteriaceae were identified in parallel by the repliscan (cathra international, ontario, canada) and api 20e (analytab products, plainview, n.y.) systems. there was a 62% agreement at the genus level between the two systems. of the 38% discrepant results, repliscan classified 22% as "biochemical pattern not on file," 8% as a multiple-genus group which included the api 20e identification, and 8% as a genus other than that designated by api 20e. relative to the ... | 1981 | 7007430 |
| spurious hydrogen sulfide production by providencia and escherichia coli species. | hydrogen sulfide production was noted in two escherichia coli strands and one provaidenica alcalifaciens (proteus inconstans a) strain isolated from clinical stool specimens durin the summer of 1979. an investigation into this phenomenon revealed the predence of eubacterium lentum, an anaerobe, growing in synergism with the enterobacteriaceae and producing h2s. the implications of this association are discssed with reference to clinical microbiology laboratory practice. | 1980 | 7000823 |
| evaluation of the four-hour micro-id technique for direct identification of oxidase-negative, gram-negative rods from blood cultures. | a 4-h micro-id technique for direct identification of oxidase-negative gram-negative rods from positive blood cultures was compared to subculture and species identification of single colonies by api 20e and micro-id, using standardized inocula. a total of 127 patients (220 positive cultures) were studied. isolates included 96 escherichia coli, 46 klebsiella pneumoniae, 7 klebsiella oxytoca, 8 enterobacter aerogenes, 17 enterobacter cloacae, 19 serratia marcescens, 2 serratia liquefaciens, 8 prot ... | 1980 | 6999020 |
| cross-reactivity of major outer membrane proteins of enterobacteriaceae, studied by crossed immunoelectrophoresis. | outer membrane fractions were prepared from 11 bacteria in the family enterobacteriaceae: escherichia coli serotypes o1k-, o4k2, o26k60, o75k-, and o111k58, shigella flexneri, salmonella typhimurium, klebsiella pneumonia, serratia marcescens, proteus vulgaris, proteus mirabilis, and providencia stuartii. all strains studied were found to contain one non-peptidoglycan-bound, heat-modifiable outer membrane protein, and one or two peptidoglycan-associated major outer membrane proteins in the 27,000 ... | 1980 | 6995435 |
| gram-negative bacteremia. iii. reassessment of etiology, epidemiology and ecology in 612 patients. | evaluation of 612 episodes of gram-negative bacteremia over a 10-year period demonstrated its progressively increasing frequency. this increase was associated with an increasing proportion of patients with more severe underlying disease, increasing patient age, increasing frequency of cardiac surgery and manipulative procedures, and increasing frequency of treatment with antibiotics, corticosteroids and antimetabolites in patients with bacteremia. fatality rates paralleled the severity of the ho ... | 1980 | 6987870 |
| infective endocarditis caused by gram-negative bacteria: a review of the literature, 1945-1977. | 1980 | 6986059 | |
| antibacterial activity and beta-lactamase stability of temocillin. | temocillin, a 6-alpha-methoxy penicillin, inhibited 90% of strains of escherichia coli, klebsiella pneumoniae, citrobacter, proteus, providencia, salmonella, and shigella at a concentration of less than or equal to 16 micrograms/ml. haemophilus influenzae and neisseria gonorrhoea were inhibited by less than or equal to 1 microgram/ml. changing the medium or ph of the cultures did not alter the minimal inhibitory concentrations, which were similar in broth and human serum, as were the minimal bac ... | 1982 | 6982681 |
| in vitro activity of apalcillin compared with that of other new penicillins and anti-pseudomonas cephalosporins. | apalcillin, a naphthydridine derivative of ampicillin, was compared with ticarcillin, azlocillin, mezlocillin, piperacillin, cefotaxime, and cefoperazone against gram-negative and gram-positive bacterial isolates and with cefsulodin and tobramycin against pseudomonas aeruginosa. the minimal concentrations of apalcillin at which 50 and 90% of hospital isolates of escherichia coli were inhibited were similar to those of mezlocillin and piperacillin (1.6 and 100 micrograms/ml, respectively). apalci ... | 1982 | 6981375 |
| purification and some properties of beta-lactamases from proteus rettgeri and proteus inconstans. | two beta-lactamases were isolated from strains of proteus species and purified, one from a strain of p. rettgeri and the other from a strain of p. inconstans. each enzyme preparation gave a single protein band on polyacrylamide gel electrophoresis. molecular weights of p. rettgeri and p. inconstans enzymes were found to be 42,000 and 43,000, and their isoelectric points ph 8.7 and 8.6, respectively. the two enzymes presented typical cephalosporinase profiles. cefmetazole (cs-1170) and cefoxitin, ... | 1980 | 6971391 |
| resistance factors: influence on netilmicin activity. | netilmicin is active against many but not all bacterial strains that have acquired resistance to aminoglycosides. generally, netilmicin is 1) active against strains that produce enzymes inhibiting aminoglycosides by phosphorylation or adenylation. some of these enzymes are widely distributed in aminoglycoside resistant strains, e.g. the adenylating enzyme ant(2") predominating in resistant klebsiella and common in resistant pseudomonas and serratia strains. netilmicin either lacks the hydroxyl g ... | 1980 | 6937969 |
| providencia rustigianii: a new species in the family enterobacteriaceae formerly known as providencia alcalifaciens biogroup 3. | the name providencia rustigianii sp. nov. is proposed for a group of organisms previously known as providencia alcalifaciens biogroup 3. by dna hybridization, strains of p. rustigianii were 81 to 99% related to each other at 60 degrees c, but only 44 to 49% related to p. alcalifaciens biogroups 1 and 2 and 26 to 33% related to providencia stuartii. p. rustigianii could be differentiated from p. alcalifaciens and p. stuartii by simple biochemical tests. p. rustigianii produced acid from d-galacto ... | 1983 | 6874899 |
| comparative in vitro activity of semisynthetic penicillins against proteeae. | the in vitro susceptibilities of 181 isolates of precisely identified proteeae species to five semisynthetic penicillins were determined with low and high inocula. significant differences in susceptibility patterns among various proteeae species to the penicillins examined were demonstrated. providencia stuartii was clearly distinguished from providencia alcalifaciens by its greater resistance to the antibiotics tested. | 1983 | 6859841 |
| the in-vitro activity of o-demethylfortimicin. | the activity of o-demethylfortimicin against ampicillin, cefazolin and carbenicillin resistant bacteria was determined. o-demethylfortimicin showed excellent in-vitro activity against escherichia coli, klebsiella pneumoniae, enterobacter cloacae, ent. agglomerans, ent. aerogenes, citrobacter freundii, proteus vulgaris, morganella, and providencia inhibiting these organisms at less than or equal to 3.1 mg/l. it was particularly effective against ent. cloacae and serratia marcescens that were resi ... | 1983 | 6833173 |
| a prospective microbiologic study of bacteriuria in patients with chronic indwelling urethral catheters. | bacteriuria is common in chronically catheterized patients and is associated with both acute and chronic complications. of 605 consecutive weekly urine specimens from 20 chronically catheterized patients, 98% contained bacteria at high concentrations and 77% were polymicrobial. the mean interval between new episodes of bacteriuria was 1.8 weeks. most species of bacteria caused five to seven new episodes of bacteriuria per 100 weeks of catheterization. even though access to the catheter lumen was ... | 1982 | 6815281 |
| [proteolytic activity of conditionally pathogenic microorganisms causing food poisoning]. | a study was made of proteolytic activity of the microorganisms proteus and bac. cereus, as well as of infected extract from raw meat. subject to study were also the effects of the temperature, storage and microbial association on the production of exoproteases. the results indicate an increase in the proteolytic activity in the course of storage at room and decreased temperatures and a lowering of the soluble protein amount in the samples, which attests to an active process of spoiling. associat ... | 1982 | 6803437 |
| superior activity of n-formimidoyl thienamycin against gentamicin-resistant pseudomonas aeruginosa. | n-formimidoyl thienamycin (n-f-thienamycin), cefotaxime, moxalactam, and cefsulodin were tested by agar dilution against 125 isolates of pseudomonas aeruginosa, serratia marcescens, klebsiella pneumoniae, and providencia stuartii. against gentamicin-susceptible p. aeruginosa, n-f-thienamycin and cefsulodin were most active. only n-f-thienamycin inhibited gentamicin-resistant p. aeruginosa at less than or equal to 4 microgram/ml. n-f-thienamycin's activity equaled or surpassed that of the other a ... | 1981 | 6798926 |
| some observations on the activity of three antiseptics used as bladder irrigants in the treatment of urinary tract infection in patients with indwelling catheters. | a comparison has been made of the activity of three antiseptics that are used as bladder irrigants in the treatment of urinary tract infection in catheterised patients. at the concentrations and exposure times used for bladder irrigation, phenoxyethanol (2:4% v/v) proved to be highly bactericidal against urine-grown cells of all the common urinary pathogens tested. chlorhexidine (200 microgram/ml) was active against escherichia coli and produced significant reductions in the viability of klebsie ... | 1981 | 6796928 |
| [bacterial etiological factors in urinary tract infections in children]. | 1981 | 6795583 | |
| use of agarose gel electrophoresis of plasmid deoxyribonucleic acid to fingerprint gram-negative bacilli. | agarose gel electrophoresis of the plasmid deoxyribonucleic acids from 60 gram-negative bacilli recovered during investigations of nosocomial epidemics was used to fingerprint the strains. this method was as specific at differentiating bacterial strains as more conventional phenotyping methods. in all cases, plasmid band fingerprints of epidermic strains isolates were identical whereas coisolate plasmid deoxyribonucleic acid patterns were different. agarose gel electrophoresis of plasmid deoxyri ... | 1981 | 6788798 |
| [evaluation of the antibacterial activity in vitro of various cephalosporins on different gram-negative bacterial species of recent clinical isolation]. | the authors have compared the antibacterial activity "in vitro" of new cephalosporines (cephuroxim, cephoxitin and cephaclor) with other cephalosporines having an action which is already known (cephaloridine, cephazoline and cephalexine) on the gram-negative bacterial strains of recent clinical isolation. the results show that the cephalosporines of last generation, having in their molecular nucleus a methoximinic group, realize a greater antibacterial protection than those cephalosporines of an ... | 1980 | 6776969 |
| uk31214, a new aminoglycoside and derivative of kanamycin b. | the in vitro activity of uk31214, a kanamycin b derivative, was studied against 250 recent isolates and compared with other aminoglycosides. against the enterobacteriaceae (with the exception of proteus mirabilis and providencia stuartii) uk31214 and amikacin had similar degrees of activity (mode minimum inhibitory concentration [mic], 1 microgram/ml). proteus mirabilis and p. stuartii strains were four- to eight-fold more susceptible to amikacin than to uk31214. pseudomonas aeruginosa strains w ... | 1980 | 6775590 |
| antiseptic and antibiotic resistance in gram-negative bacteria causing urinary tract infection. | a collection of 802 isolates of gram-negative bacteria causing urinary tract infections was made from general practice, antenatal clinics, and local hospitals. the organisms were tested for their sensitivity to chlorhexidine, cetrimide, glutaraldehyde, phenyl mercuric nitrate, a phenolic formulation, and a proprietary antiseptic containing a mixture of picloxydine, octyl phenoxy polyethoxyethanol, and benzalkonium chloride. escherichia coli, the major species isolated, proved to be uniformly sen ... | 1980 | 6769972 |
| purification of the sequence-specific endonuclease pal i. | 1981 | 6765643 | |
| species differences in susceptibilities of proteeae spp. to six cephalosporins and three aminoglycosides. | six cephalosporins and three aminoglycosides were examined for activity against 1,693 isolates belonging to six species of proteeae. the most notable species-specific differences included the marked susceptibility of providencia alcalifaciens and proteus mirabilis to cephalothin, the resistance of proteus vulgaris to cefamandole, and the resistance of providencia stuartii to gentamicin and tobramycin. the third-generation cephalosporins cefotaxime and moxalactam were substantially more inhibitor ... | 1982 | 6765415 |
| short-course aminoglycoside therapy in patients with spinal cord injury. standard dose versus low dose. | twenty-nine patients with spinal cord injury and asymptomatic urinary tract infection were treated with standard or reduced doses of tobramycin and amikacin. the patients received five days of intramuscular antibiotics. most of the patients in the tobramycin groups had pseudomonas aeruginosa infection and most of those in the amikacin group had either proteus rettgeri or providencia stuartii infections. only 1 patient had a positive urine antibody coating test. high antibiotic concentrations wer ... | 1980 | 6763394 |
| comparison of three methods for identification of enterobacteriaceae. | this study compares the ability of three commercial overnight methods, api 20e, minitek and enteric-tek, to accurately and completely identify 368 clinically isolated enterobacteriaceae without supplemental tests. organisms included escherichia coli (54 strains), shigella spp. (7), edwardsiella tarda (1), salmonella enteritidis (10), citrobacter spp. (30), klebsiella spp. (55), enterobacter spp. (68), hafnia alvei (2), serratia spp. (33), proteus spp. (64), morganella morganii (24), providencia ... | 1982 | 6756905 |
| five-year surveillance of aminoglycoside usage in a university hospital. | because an increased incidence of nosocomial bacteremia due to gentamicin-resistant organisms occurred in our hospital, amikacin was substituted for gentamicin as the primary empiric aminoglycoside. prospective surveillance of aminoglycoside use and of bacterial resistance to aminoglycosides was done before and after the substitution. we compared the baseline period when gentamicin was the primary aminoglycoside with the subsequent period when amikacin accounted for 81% of aminoglycoside used. d ... | 1984 | 6691664 |
| freeze-dried mixed cultures as samples for proficiency tests and collaborative studies in food microbiology. | a method is presented for preparing samples of freeze-dried mixtures of microorganisms for proficiency tests and collaborative studies. the samples may include most microorganisms that are found in routine analysis in food laboratories. transport of samples during 48 h did not decrease the number of microorganisms, nor was the variability among samples significantly affected by transport. the standard deviation of counts after 5 weeks of storage varied from 0.04 (staphylococcus aureus) to 0.17 ( ... | 1983 | 6643366 |
| panophthalmitis and otitis interna in fire-bellied toads. | microbiologic and histologic studies were made of fire-bellied toads with signs of ocular and central nervous system disease. providencia alcalifaciens, citrobacter freundii, aeromonas hydrophila, and other gram-negative bacilli were isolated from the eyes and multiple tissues of ill toads. the histologic evaluations revealed severe panophthalmitis and otitis interna. | 1983 | 6643232 |
| resistance of gram-negative bacilli as related to hospital use of antimicrobial agents. | the development of resistance of gram-negative bacilli, which are common nosocomial pathogens, is an increasing problem. it is generally accepted that this resistance may directly reflect the frequency of use of various antimicrobial agents. because our institution experienced in 1976 a dramatic change in the pattern of antimicrobial use, primarily a marked decrease in prescribing cephalosporins, we attempted to evaluate retrospectively the effects of this change upon the resistance of gram-nega ... | 1983 | 6638994 |
| epidemiology of gentamicin-resistant, gram-negative bacillary colonization in a spinal cord injury unit. | a prospective epidemiological survey of a spinal cord injury unit for gentamicin-resistant, gram-negative bacilli was undertaken. the initial survey of the unit suggested a low level of cross-infection involving pseudomonas aeruginosa and providencia stuartii. however, a longitudinal study of new admissions revealed that only 13 of 52 nosocomial acquisitions could be considered to be due to cross colonization. comparison of data on antibiotic use did not suggest selective pressure for resistant ... | 1983 | 6619279 |
| in vitro activity of fludalanine combined with pentizidone compared with those of other agents. | the in vitro activity of fludalanine ( mk641 ) combined with pentizidone ( mk642 ) so as to give a fludalanine /d-cycloserine ratio of 1:1 was compared with the activities of ampicillin, ticarcillin, cefuroxime, ceftazidime, and trimethoprim against 452 recent isolates and known beta-lactam- and trimethoprim-resistant strains. in addition, the in vitro activity of fludalanine - pentizidone on four different media, including a defined medium ( dfn -2), was studied. the mic of fludalanine - pentiz ... | 1984 | 6610389 |
| detection of pse-2 beta-lactamase in enterobacteria. | pse-2, a plasmid-mediated beta-lactamase which was previously considered pseudomonas specific, was observed in clinical isolates of escherichia coli, klebsiella pneumoniae, providencia stuartii, and enterobacter cloacae. all four isolates transferred pse-2 production, together with resistance to gentamicin, tobramycin, kanamycin, and sulfamethoxazole, into escherichia coli j62-1 and pseudomonas aeruginosa pu21. transfer correlated with acquisition by the transconjugants of a 65-megadalton plasmi ... | 1984 | 6608920 |
| in vitro antibacterial activity and beta-lactamase stability of e-0702, a new cephalosporin. | the in vitro activity of e-0702 was compared with the in vitro activity of cefotaxime, ceftazidime, moxalactam, and aztreonam against 600 gram-positive and gram-negative aerobic and anaerobic isolates. e-0702 had a minimal inhibitory concentration for 50% of isolates (mic50) of 25 micrograms for staphylococcus aureus, 50 micrograms for staphylococcus epidermidis, and 1.6 to 3.1 micrograms for streptococci, with streptococcus faecalis resistant. e-0702 had mic50s against escherichia coli, klebsie ... | 1983 | 6605718 |
| cefotetan: profile of in-vitro activity. | cefotetan, a novel 7 alpha-methoxy cephalosporin, was shown to be comparable to other third-generation cephalosporins when tested in vitro against 1063 gram-negative clinical isolates of 11 species. ninety per cent of all isolates of escherichia coli, klebsiella, proteus mirabilis, proteus vulgaris, proteus rettgeri, providencia stuartii, serratia marcescens and citrobacter freundii were inhibited by concentrations of cefotetan between 0.07 and 3.2 mg/l. activity against gram-positive cocci was ... | 1983 | 6601656 |
| in-vitro activity of enoxacin (cl-919), a new quinoline derivative, compared with that of other antimicrobial agents. | the in-vitro activity of enoxacin (ci-919), a new synthetic quinoline derivative was compared with that of three other quinolines ofloxacin, norfloxacin and nalidixic acid. in addition beta-lactams and gentamicin were also included when appropriate. the mics of enoxacin for 90% of escherichia coli, klebsiella spp., enterobacter spp., proteus spp., providencia stuartii, pseudomonas aeruginosa and staphylococcus aureus were less than 4 mg/l, for haemophilus influenzae less than 0.25 mg/l and neiss ... | 1984 | 6586712 |
| susceptibilities of gentamicin-resistant gram-negative aerobic bacilli to cefotetan and other beta-lactams. | the activity of the 7 alpha-methoxycephalosporin, cefotetan was determined against 365 infecting isolates of gentamicin- and multiply-resistant gram-negative aerobic bacilli, and compared with those of cefuroxime, cefoxitin, cephradine, cefotaxime, ceftriaxone and ceftazidime. all proteus (4), providencia (6) salmonella (3) and serratia (2) were susceptible to 8 mg/l of cefotetan, as were respectively 90 and 81% of 42 escherichia coli and 16 citrobacter isolates. the intrinsic activity of cefote ... | 1983 | 6573329 |
| a prevalence survey of infections in a combined acute and long-term care hospital. | a prevalence survey of infections among 572 acute and long-term care patients in the albany veterans administration medical center was conducted in september 1979. presence of infection was determined by patient examination and chart review. urine specimens from 94% of patients were cultured. the total number of clinically significant infections was 178; 117 were nosocomial (20.5 per 100 patients). the prevalence rate of nosocomial infections was highest on the intermediate service (long-term me ... | 1984 | 6562090 |
| in vitro and in vivo antibacterial properties of fk 027, a new orally active cephem antibiotic. | fk 027 was more active than cefaclor, cephalexin, and amoxicillin against stock strains of a wide variety of gram-negative bacteria, including such opportunistic pathogens as citrobacter and enterobacter species and serratia marcescens. fk 027 was significantly more active than the three reference drugs against clinical isolates of escherichia coli, klebsiella pneumoniae, indole-positive and -negative proteus species, providencia species, haemophilus influenzae, and neisseria gonorrhoeae. it was ... | 1984 | 6561017 |
| in vitro and in vivo antibacterial activities of k-4619, a new semisynthetic aminoglycoside. | the antibacterial activities of k-4619 (3-de-o-methylsporaricin a sulfate) were compared with those of sporaricin a, amikacin, dibekacin, and gentamicin. k-4619 exhibited a high order of activity against gram-positive and gram-negative bacteria, including pseudomonas aeruginosa. its activity against providencia species and serratia marcescens was the highest of all drugs tested. k-4619 was highly effective against bacteria that produce various aminoglycoside-inactivating enzymes, except for 3-ac ... | 1984 | 6548350 |
| characterization of endemic providencia stuartii isolates from patients with urinary devices. | providencia stuartii has emerged as a significant nosocomial urinary tract pathogen. an increase in the number of providencia isolates from urine cultures prompted an investigation into the possibility of an outbreak due to this organism. a high proportion of patients studied had urinary devices. four wards were screened at two time periods to ascertain the prevalence of providencia stuartii in urine cultures. biotype, serotype, antibiogram and plasmid content were determined for each providenci ... | 1984 | 6526019 |