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bacterial endocarditis due to kingella kingae.a case of infective bacterial endocarditis due to kingella kingae in a 26 year old male involving a prosthetic mitral valve is described. microbiological features of this organism are outlined, and the treatment of this endocarditis is discussed with reference to the four previously reported cases.19836578452
a pitfall in purulent arthritis brought out in kingella kingae infection of the knee.a description of the protracted course of kingella monoarthritis is given as an illustration of the importance of accounting for the slow growth, low viable numbers, and fastidious culture requirements of microbes that may be encountered in synovial samples. the practice of carrying out synovial fluid cultures in the same way as blood cultures is recommended.19846476925
kingella kingae osteomyelitis of the clavicle.kingella kingae is the most recent addition to the list of etiologic agents causing osteomyelitis and septic arthritis in previously well children. a case is presented of a child with k. kingae osteomyelitis of the clavicle--an uncommon site of infection due to any organism. in the hope of facilitating the detection and treatment of this increasingly recognized pathogen, a brief discussion of its microbiologic characteristics and a summary of the patients reported to date with bone and joint inf ...19846470125
septicemia caused by kingella kingae.a case of kingella kingae septicemia following acute gastroenteritis is described. intravenous antibiotic treatment with mezlocillin and tobramycin led to rapid and sustained recovery. the infection with kingella kingae may have been food-borne.19846468371
endocarditis due to kingella kingae.four cases of endocarditis due to kingella kingae are described in compromised patients. all had primary heart disease, and two had systemic lupus erythematosis and congenital heart defect respectively, in addition. confirmation of kingella kingae was made in one case at autopsy. the literature on 11 cases of endocarditis, 2 bacteremia, 4 osteomyelitis, 5 septic arthritis and 1 intervertebral disc infection, all caused by kingella kingae, is reviewed. our findings confirm that the organism is of ...19846468370
acute kingella kingae endocarditis with recurrent cerebral emboli in a child with mitral prolapse.an 11-year-old girl had sudden onset of right hemiplegia and dysphasia with fever. blood cultures grew kingella kingae. echocardiography showed a prolapsed mitral valve vegetation, which became larger during a prolonged course of antibiotics. after seven weeks of therapy, when surgery was being planned, the child deteriorated abruptly. a repeat echocardiogram showed that the vegetation had disappeared. conservative medical management is usually inadequate in treating vegetations associated with ...19846465865
kingella kingae septicaemia with a clinical presentation resembling disseminated gonococcal infection. 19846434059
identification and characterization of kingella kingae.kingella kingae is a rarely isolated opportunistic pathogen in the family neisseriaceae. thirteen strains of this organism, including six strains isolated in denmark, were characterized. they formed a homogeneous group of small, non-motile, fastidious gram-negative rods which were beta-haemolytic, oxidase positive, catalase negative and saccharolytic. acid was produced for glucose and maltose. growth was most pronounced aerobically but corroding colonies increased considerably in size during ana ...19816274144
corroding bacteria from the respiratory tract. 1. moraxella kingii. 19695796084
moraxella kingii sp.nov., a haemolytic, saccharolytic species of the genus moraxella. 19685185818
the serology of moraxella kingii. 19694986754
fimbriation associated with the spreading-corroding colony type in moraxella kingii. 19724508780
kingella kingae infections: a review and a presentation of data from 10 swedish cases.kingella kingae is a fastidious gram-negative rod related to the neisseriae. together with data from published cases of k. kingae infection, we report the clinical and laboratory findings from 10 cases in western sweden; a specific serological reaction is also described. the diagnoses were osteomyelitis, septic arthritis, discitis, endocarditis, occult bacteraemia and phlegmon. the data from the swedish cases, together with those from previous reports in the literature provided the basis for an ...19854059864
[kingella kingae--a new infectious agent]. 19853990452
[acute endocarditis caused by kingella kingae in an infant].a case of bacterial endocarditis in a one year-old boy is reported. there was no underlying heart disease. the organism was a kingella kingae, an aerobic gram negative bacillus, a normal inhabitant of the upper respiratory tract. it has rarely been implicated as a pediatric pathogen. occasionally it can cause bone and joint infections and exceptionally endocarditis.19853985754
evaluation of the rim system and gono gen test for identification of neisseria gonorrhoeae from clinical specimens.rim-n (austin biological laboratories) and gono gen (micro media systems) were evaluated for accuracy and compared with conventional carbohydrate degradation tests for identification of neisseria gonorrhoeae. a total of 127 fresh clinical isolates of n. gonorrhoeae were tested; 118 (93%) were identified by rim-n, and 100 (79%) yielded positive reactions with gono gen. seventy nongonococcal isolates including other neisseria species, branhamella catarrhalis, kingella kingae, and moraxella species ...19853919991
[osteoarthritis and osteomyelitis due to kingella kingae in children. apropos of 5 cases and review of the literature].bone infection caused by kingella kingae (kk) is rare since there are only 15 published cases. we report 5 additional cases with isolation of kk from fluid or bone aspiration. kk was sensitive to the most common antibiotics. the outcome was favorable in every case.19863808839
isolation of two strains of kingella kingae associated with septic arthritis.two new cases of infection, a presternal abscess and a spondylodiscitis caused by the recently classified bacterium kingella kingae, are reported. the main bacteriological characteristics and the susceptibility of the two isolates to antimicrobial agents are described. the pathology of k. kingae, particularly among children, is reviewed.19863782457
[a new human bacteriosis: infection with kingella kingae]. 19863764217
infections caused by kingella kingae: report of four cases and review.kingella kingae, formerly known as moraxella kingae, is a fastidious, non-motile, coccobacillary, fermentative gram-negative rod that has been chiefly associated with two types of infections in man: bone and joint infections, and endocarditis. we describe four patients with k. kingae infections, one with septicaemia, two with endocarditis, and one with osteoarthritis. the current literature on infections with k. kingae is reviewed.19863760596
manifestations of kingella kingae infections in adults: resemblance to neisserial infections.kingella kingae is a rare human pathogen. most reported infections are in children and involve endocardium, vascular space, and skeletal tissues. we report herein two cases of k. kingae infection recently seen in adults. kingella kingae caused acute meningitis in a patient with sickle cell anemia and in the second patient with alcoholic liver disease, sepsis with a petechial rash. the clinical presentation due to k. kingae closely resembled that caused by related neisseria genus.19863709097
intervertebral diskitis caused by kingella kingae.a case of childhood intervertebral diskitis caused by kingella kingae is presented. in a review of the literature, the authors found 33 reported cases of infection caused by species of the kingella genus, of which 29 were due to k. kingae. of the 33 cases, 42% represented bacterial endocarditis and 48% bone and joint infection. of the 16 bone and joint infections, 11 represented septic arthritis, 3 osteomyelitis, and 2 intervertebral diskitis, the latter finding making the authors' case of k. ki ...19863706211
kingella kingae septicaemia. 19873591214
[osteoarthritis due to kingella kingae. apropos of 4 cases].the authors describe for cases of osteoarthritis with kingella kingae, among children. this gram less than 0 germ, which is not well known, tends to be located in bones and joints. in the light of for observations and some of the cases yet observed, we could identified the clinical, biological, and bacteriological characteristics of this germ that has been just described.19863581309
use of intravenous ciprofloxacin in difficult-to-treat infections.intravenous ciprofloxacin was administered to 54 patients who were either critically ill or in whom oral administration was not possible. the 31 males and 23 females ranged in age from 20 to 89 years (mean, 53.2 +/- 17.8 years). patients had "difficult-to-treat" infections, i.e., respiratory infections (15), abscesses (four intraabdominal, three lung, two soft tissue, and one intrahepatic), deep soft tissue infections (10), chronic post-traumatic osteomyelitis in exacerbation (nine), upper urina ...19873555059
imipenem and cilastatin in acute osteomyelitis and suppurative arthritis. therapy in infants and children.twenty-five infants and children with acute osteomyelitis (n = 7), suppurative arthritis (n = 11), or both (n = 7) were treated with imipenem and cilastatin sodium. patients ranged in age from 5 months to 11.3 years. needle aspiration of infected sites was performed in all patients, and 11 (44%) required further surgical drainage. imipenem and cilastatin sodium in a dosage of 100 mg/kg/d was used for children 3 years of age or younger, while older ones received 60 mg/kg/d intravenously, divided ...19873544811
[sensitivity of kingella kingae to antibiotics].kingella kingae is a small gram negative rod of the neisseriaceae family, formerly called moraxella kingae. this microorganism is found occasionally in the oral cavity and is capable of causing infections. we report three cases of septic arthritis in children due to k. kingae. in vitro susceptibility of the recovered strains was tested using determination of mics in agar. the strains were susceptible to penicillin, ampicillin, ticarcillin, cephalothin, cefotaxime, gentamicin, chloramphenicol, te ...19863534752
spondylitis and osteomyelitis caused by kingella kingae in children.two cases of documented osteoarticular infections caused by kingella kingae in children are reported. the main bacteriological characteristics and antibiotic susceptibilities of these two isolates are described. the pathology of k. kingae, particularly in bones and joints, is reviewed.19873429633
osteomyelitis due to kingella kingae infection.a case of osteomyelitis due to kingella kingae is presented to illustrate the insidious onset and indolent course typical of bone infections caused by this organism. the frequently negative result obtained with gram's stain and the fastidious nature of the organism makes diagnosis difficult. initial therapy with an aminopenicillin such as ampicillin in addition to antimicrobial drugs for staphylococcus aureus should be effective in resolving bone and joint infections in children.19883337967
kingella kingae osteoarthritis and osteomyelitis in children.kingella kingae is still a poorly understood germ which is responsible for osteoarticular infections. we observed nine cases of osteoarthritis involving k. kingae in children. they included 4 cases of arthritis, 2 of osteomyelitis, and 3 of spondylodiscitis. the germ was cultured in all cases by direct surgical approach or by needle aspiration of the septic locus. evolution was always good after immobilization and nonspecific antibiotherapy. our nine clinical cases, along with the few cases alre ...19883335623
endocarditis caused by kingella indologenes.the first known case of endocarditis caused by kingella indologenes is reported. a review of the literature reveals only seven cases of endocarditis caused by the other two species of the genus kingella (kingella kingae, six cases; kingella denitrificens, one case). kingella organisms appear to be sensitive to a wide variety of antimicrobial agents. the available data suggest that endocarditis caused by kingella species occurs rarely and is associated with a benign clinical course.19873326125
kingella kingae endocarditis: report of a case and review of the literature. 19873308781
kingella kingae infection in healthy children.kingella kingae is a gram-negative occasional, but normal, inhabitant of the nasopharynx. we present two new cases of this infection that occurred in previously healthy children, and compare and contrast them to other cases reported in the literature. k. kingae osteomyelitis generally has an insidious, subacute onset, whereas septic arthritis has an acute presentation. to date, all strains of k. kingae have been sensitive to penicillin, and no residual damage has been reported following osteomye ...19883292580
kingella kingae bacteremia and adult epiglottitis in a granulocytopenic host. 19883189372
kingella kingae osteomyelitis: report of two cases involving the epiphysis. 19883134646
[infective endocarditis due to kingella kingae in a patient with systemic lupus erythematosus]. 19873130447
bone and joint infections caused by kingella kingae: six cases and review of the literature.six cases of kingella kingae arthritis, osteomyelitis, and diskitis were studied, and data were reviewed from an additional 23 cases in the english-language literature. k. kingae is a slow-growing, fastidious, gram-negative microorganism that colonizes mucous membranes of the upper respiratory tract. infections were predominantly seen in infants and young children (86% of cases) and were preceded by an upper respiratory tract infection in 31% of patients. low-grade fever (38 degrees c-39 degrees ...19883055196
cellular fatty acid composition of kingella species, cardiobacterium hominis, and eikenella corrodens.we determined the cellular fatty acid composition of reference strains and clinical isolates of each of the three kingella species, cardiobacterium hominis, and eikenella corrodens by using capillary gas chromatography. kingella denitrificans and kingella kingae contained myristic (14:0) and palmitic (16:0) acids as major acids, whereas cis-vaccenic (18:1 omega 7c) and palmitic acids were the major acids in kingella indologenes, c. hominis, and e. corrodens. c. hominis differed from the other fo ...19883049663
differentiation of some species of neisseriaceae and other bacterial groups by dna-dna hybridization.dna-dna hybridization using total genomic dna probes may represent a way of differentiating between miscellaneous bacterial species. this was studied with type and reference strains of 20 species in moraxella, kingella, and other selected gram-negative groups. both radioactive and biotin labelling were employed. most of the species examined were easily distinguished, such as moraxella (branhamella) catarrhalis, m.(b.) ovis, m. atlantae, m. phenylpyruvica, m. osloensis, neisseria elongata, n. men ...19892730785
[kingella kingae osteomyelitis].a case of kingella kingae osteomyelitis characterized by an early onset of cellulitis, positive blood culture and negative bone scintigraphy is reported. exclusive of vertebral involvement, eleven cases have been described in the pediatric literature. the bacterial nature of this disorder may prove hard to demonstrate since fever, leucocytosis, and increased crp levels are inconstant. the difficulties of isolation and growth of kingella kingae as well as its likely resistance to antistaphylococc ...19892688590
clinical manifestations of kingella kingae infections: case report and review.a patient with antecedent coccidioidal pulmonary cavitary disease who developed an empyema due to kingella kingae prompted our analysis of the literature regarding this unusual bacterial pathogen. formerly classified among other genera and considered a nonpathogen, k. kingae has been increasingly recognized as a cause of human infection. while the most commonly diagnosed infections due to this organism are endocarditis and septic arthritis, there have also been isolated reports of bacteremia, di ...19892682950
kingella kingae endocarditis in a patient with the acquired immunodeficiency syndrome. 19892603424
[the isolation of kingella kingae by hemoculture must always suggest the diagnosis of endocarditis]. 19892529496
infections caused by moraxella, moraxella urethralis, moraxella-like groups m-5 and m-6, and kingella kingae in the united states, 1953-1980.from 1953 to 1980 the centers for disease control received 933 isolates of bacteria belonging to species of the genus moraxella, moraxella-like moraxella urethralis, now renamed oligella urethralis, unnamed groups m-5 and m-6, and kingella kingae. ordinarily sterile sites were the source of 233 isolates. moraxella nonliquefaciens, the most common isolate (356 strains), was recovered from upper respiratory or ocular sites in 208 (58%) of the cases. moraxella osloensis was next most common (199 st ...19902359906
[cervical spondylodiscitis caused by kingella kingae. apropos of a case].we report a new case of spondylodiscitis due to kingella kingae in a 19-month-old infant who had torticollis as the first manifestation. the main characteristics of kingella kingae infections are reviewed: frequency of ent and joint localizations, slow course, difficult clinical and bacteriological diagnosis, and satisfactory susceptibility to antimicrobial agents.19902350142
polymicrobic septic arthritis caused by kingella kingae and enterococcus. 19902308886
kingella kingae intervertebral disk infection.disk inflammation in children is believed to result from infection, and staphylococcus aureus is reported to be the organism most commonly isolated from cases of intervertebral disk infection. a case of disk inflammation caused by the unusual pathogen kingella kingae is described. the antibiotic susceptibility of other k. kingae isolates and the clinical features of 11 other previously reported cases of disk infection caused by this microorganism are reviewed.19912056049
kingella kingae dactylitis in an infant. 19912002223
kingella kingae endophthalmitis in an infant.an 11-month-old girl presented with metastatic endophthalmitis. the causative organism was the gram-negative coccobacillus kingella kingae. this is an uncommon organism first recognised in 1967. it has never been previously reported to cause endophthalmitis, but is associated with at least four other infective syndromes in children. endophthalmitis is a potentially lethal and sight-threatening disease. kingella kingae is primarily a paediatric pathogen which fortunately responds well to antibiot ...19911958367
kingella kingae infection in children: ten cases and a review of the literature. 19911923682
osteoarticular infections due to kingella kingae in children.by the description of two cases of osteoarticular infections due to kingella kingae in two young children we wish to draw the attention of clinicians to invasive infections due to this micro-organism. since its biological characterization in 1976, k. kingae has been increasingly reported as a human pathogen. most common presentations are endocarditis, bacteraemia, septic arthritis, osteomyelitis and spondylodiscitis. interestingly, osteorticular involvement is largely predominant in previously h ...19911915510
kingella kingae meningitis in an infant. 19911885909
application of quadferm+ for the identification of fastidious gram-positive and gram-negative bacilli.the 2-hr quadferm+ kit (qf) (analytab products, plainview, ny) was compared with conventional tube tests for the identification of the hacek bacteria (haemophilus aphrophilus, actinobacillus actinomycetemcomitans, cardiobacterium hominis, eikenella corrodens, kingella kingae), other haemophilus and kingella spp., capnocytophaga, corynbacterium, and moraxella spp. test results were identical for 296 comparisons with 74 isolates (74%). in the remaining 104 comparisons for 26 isolates, 50 reactions ...19911873978
high prevalence of kingella kingae in joint fluid from children with septic arthritis revealed by the bactec blood culture system.in an effort to improve detection of fastidious organisms, joint fluid aspirates of pediatric patients were inoculated into bactec 460 aerobic blood culture bottles, in addition to cultures on solid media. culture records for the 1988 to 1991 period were reviewed to compare the performance of both methods for the recovery of pathogens. overall, 216 children underwent a diagnostic joint tap, and 63 specimens grew significant organisms, including kingella kingae in 14. while both methods were comp ...19921583131
kingella kingae infection in children. 19921565566
kingella kingae intervertebral diskitis in an adult.kingella kingae rarely causes infection and is mainly associated with endocarditis and septic arthritis in adults. the organism is also capable of causing intervertebral diskitis in children, but thus far, no reports of this infection occurring in adults have been published. a case of diskitis due to k. kingae in an adult is reported for the first time, and the literature on this infection in children is reviewed.19921520804
isolation of kingella kingae from a corneal ulcer.kingella kingae was isolated from a corneal ulcer in an 11-month-old male. this organism has been previously reported from normally sterile sites, including sites of endophthalmitis, but this is the first time isolation from the cornea has been reported.19921401031
kingella kingae, a rare cause of bacterial meningitis.a male adolescent with a history of pharyngitis developed meningitis due to kingella kingae. this is a gram-negative coccobacillus belonging to the family of neisseriaceae. it is a rarely reported human pathogen, from which only 2 cases of meningitis have been described up to the present day. our patient developed ophthalmoplegia, suggestive of basal meningitis. he was treated with penicillin g and recovered completely.19921324818
relationship of neisseria elongata subsp. glycolytica to other members of the family neisseriaceae.neisseria elongata subsp. glycolytica strain 6171/75 is closely similar to the type strain of n. elongata, m2, as regards dna base composition, fatty acid content and electrophoretic mobility of two glutamate dehydrogenases, one of which showed a reaction of identity with the corresponding enzyme from m2 in double immunodiffusion in agar. the strain showed genetic homologies with strain m2 in genetic transformation at a level suggesting species identity, and with n. meningitidis at a lower level ...1977842351
infective endocarditis caused by moraxella kingae. 1978716391
paraspinal mass associated with intervertebral disk infection secondary to moraxella kingii. 1978619089
oxidase positive rods from cases of suspected gonorrhoea. a comparison of conventional, gas chromatographic and genetic methods of identification.genito-urethral specimens from 3260 women and 1170 men, with ailments suggestive of gonorrhoea, were examined for growth of oxidase positive rodshaped bacteria, as well as of gonococci. moraxella osloensis was identified in 26 cases (0.64 per cent of women and 0.43 per cent of men). three patients harboured phenylalanine negative (or weakly reacting) and tryptophan deaminase negative m. phenylpyrouvica and, in three cases, a flavobacterium species was detected. among six oropharyngeal specimens ...1977402788
density gradient centrifugation in urografin of moraxella and kingella cells and appendages.purification of fimbriae (pili) by density gradient banding in urografin medium was attempted. moraxella nonliquefaciens and kingella kingae fimbriae were of higher density than their cells of origin, but fimbrial fractions obtained by homogenization and differential centrifugation still banded together with presumed outer membrane fragments and some whole cells in urografin gradients. the cellular density of genetic variants with different fimbriation/competence levels was also studied. for one ...1978358743
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