Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
|---|
| [cefotetan in the therapy of respiratory infections. multicenter research]. | in a controlled multicenter trial 291 patients have been treated with cefotetan. they suffered from acute or chronic exacerbated bronchopulmonary disorders. in 110 patients it was possible to identify the etiological agent: enterobacteria (62), non-fermentative gram-negative bacilli (10), haemophilus influenzae (8), branhamella catarrhalis (1), streptococcus pneumoniae (19), staphylococcus aureus (12), streptococcus pyogenes (4). in the exacerbations of chronic bronchitis (203), cefotetan was ge ... | 1989 | 2530028 |
| [bacteriological, pharmacokinetic and clinical studies on clarithromycin in the pediatric field. pediatric study group of clarithromycin]. | clarithromycin (te-031, a-56268), a new macrolide antibiotic agent, was evaluated bacteriologically and clinically for its efficacy and safety in pediatrics by a study group organized with pediatricians from all over the country. a summary of the results of the evaluation is as follows. 1. absorption and excretion pharmacokinetics of te-031 was examined by single oral administration of 10% granules and 50 mg tablets at doses of 1, 5, 10 and 15 mg/kg. there were no significant differences between ... | 1989 | 2526259 |
| [clinical evaluation of clarithromycin in pediatric patients]. | a clinical evaluation of clarithromycin (te-031, a-56268), a newly synthesized macrolide antibiotic, was made for its efficacy and safety in 30 patients with ages ranging from 8 month-old to 12 year- 2 month-old with mycoplasmal and bacterial infections. the obtained results are summarized below. 1. a pharmacokinetic study following oral administration of te-031 at 10 mg/kg (granule) or 5.5 mg/kg (tablet) resulted in blood concentrations and urinary recovery rates higher than with other macrolid ... | 1989 | 2526247 |
| [laboratory and clinical studies on clarithromycin in the field of pediatrics]. | laboratory and clinical studies on clarithromycin (te-031, a-56268), a new macrolide antibiotic, were carried out in the field of pediatrics. the results obtained are summarized as follows: 1. serum concentrations, urinary concentrations and urinary recovery rates were determined upon oral administration on fasting of te-031 at doses of 5 mg/kg granules in 1 case and tablets in 2 cases, and 10 mg/kg granules in 1 and 15 mg/kg granules in 1. peak serum levels were obtained at 30 minutes in 2 case ... | 1989 | 2526245 |
| bronchiolitis like presentation of branhamella catarrhalis bronchopulmonary infection. | 1989 | 2517124 | |
| colonization with potentially pathogenic respiratory tract bacteria. a household study. | a group of 235 persons (180 adults and 55 children 0-15 years old) recorded symptoms of upper respiratory tract infection daily during two three-month periods (autumn 1986 and spring 1987). samples for culture were taken from the nasopharynx and throat once during each period. fifteen per cent of asymptomatic subjects harboured respiratory pathogens in the nasopharynx, as did 28% of those subjects with minor respiratory tract infections and 46% of those with more severe respiratory tract infecti ... | 1989 | 2516640 |
| the comparative activity of lomefloxacin (sc-47111, ny-198) and other orally absorbable agents against haemophilus influenzae and branhamella catarrhalis. | we compared the in vitro activity of lomefloxacin with that of other agents against 336 strains of haemophilus influenzae and branhamella catarrhalis isolated from the respiratory tract of a predominantly adult and in-patient population. h. influenzae strains were usually not serotypable. no strains were resistant to lomefloxacin; all strains tested were susceptible to 0.25 micrograms/ml. the lomefloxacin mic50 and mic90 was 0.125 micrograms/ml. | 1989 | 2515026 |
| bro beta-lactamases of branhamella catarrhalis and moraxella subgenus moraxella, including evidence for chromosomal beta-lactamase transfer by conjugation in b. catarrhalis, m. nonliquefaciens, and m. lacunata. | two closely related beta-lactamases, bro-1 and bro-2 (formerly called ravasio and 1908), are found in moraxella (branhamella) catarrhalis. we screened strains of b. catarrhalis recovered in the united states since 1952 and identified the first beta-lactamase-positive isolate in august 1976. the prevalence of the enzymes among 394 clinical isolates from one texas hospital has averaged 75% since testing began in 1983. screening of isolates of moraxella subgenus moraxella revealed the bro enzymes i ... | 1989 | 2514622 |
| bacterial tracheitis caused by branhamella catarrhalis. | 1989 | 2514416 | |
| presence of branhamella catarrhalis alters the survival of streptococcus pneumoniae and haemophilus influenzae in middle ear effusion: an in vitro study. | viable and non-viable b. catarrhalis were mixed together with s. pneumoniae and h. influenzae and injected into non-bacterial mucoid effusion material collected from the middle ear of patients with a present secretory otitis media. the samples were incubated at 37 degrees c. presence of viable b. catarrhalis could evidently prolong the survival of both s. pneumoniae and h. influenzae. presence of non-viable b. catarrhalis could also enhance the growth of s. pneumoniae, but not h. influenzae. in ... | 1989 | 2514235 |
| esterase electrophoresis: a molecular tool for studying the epidemiology of branhamella catarrhalis nosocomial infection. | a new epidemiologic typing method based on electrophoresis of esterases had been developed for differentiating between clinical isolates of branhamella catarrhalis. twenty-two epidemiologically significant strains obtained from three chest units, a paediatric intensive care unit and a paediatric unit were compared with 54 randomly selected strains and 4 reference strains, including the species type strain, atcc 25238. thirty-four distinct zymotypes were characterized by polyacrylamide-agarose ge ... | 1989 | 2514110 |
| branhamella catarrhalis as a cause of acute purulent pericarditis. | 1989 | 2513360 | |
| the significance of branhamella catarrhalis in bronchopulmonary infection--a case-control study. | data, including clinical features of bronchopulmonary infections, i.e. cough with purulent sputum, fever, peripheral blood leucocytosis, patchy pulmonary shadows on chest radiographs and the presence of crepitations or dullness on examination of the chest, were prospectively recorded in 107 consecutive adult patients whose expectorated sputum yielded branhamella-like bacterial colonies in routine cultures. subsequently, isolates from 26 patients were confirmed to be branhamella catarrhalis. of 8 ... | 1989 | 2513358 |
| comparative in vitro activity of the new oral penem alp-201 against aerobic and anaerobic bacteria. | the in vitro activity of the new penem derivative alp-201 against 226 aerobic and 350 anaerobic clinical bacterial isolates was determined using agar dilution techniques. for comparison amoxicillin, cefaclor, ceftazidime, doxycycline, erythromycin, imipenem and trimethoprim/sulfamethoxazole were also tested with aerobic bacteria, and cefoxitin, chloramphenicol, clindamycin, imipenem, metronidazole and piperacillin with anaerobic bacteria. alp-201 was found to be highly active against escherichia ... | 1989 | 2512142 |
| interaction between streptococcus pneumoniae and branhamella catarrhalis obtained from double-colonized, healthy nasopharynx and double-infected, diseased middle ear cavity. | streptococcus pneumoniae and branhamella catarrhalis were obtained from the double-colonized nasopharynx of 3 healthy carriers and from the double-infected middle ear cavity of 3 patients suffering from acute otitis media. the bacterial strains were isolated and injected both separately and together into brain-heart infusion broth. separately injected, both s. pneumoniae and b. catarrhalis survived in the broth for at least 48 h. when injected together, b. catarrhalis was completely suppressed a ... | 1989 | 2511622 |
| comparative evaluation of cefuroxime axetil and cefaclor for treatment of acute bacterial maxillary sinusitis. | cefuroxime axetil, a new beta-lactamase-stable cephalosporin, was compared with cefaclor for the treatment of acute bacterial maxillary sinusitis in 106 adult patients. direct sinus aspirations for quantitative bacterial culture were done for all patients before treatment; aspiration was repeated for most patients after treatment. pretreatment sinus aspirates were positive for 63 of 134 sampled sinuses. of specimens yielding at least 10(4) cfu/ml, haemophilus influenzae (38%) and streptococcus p ... | 1989 | 2510772 |
| tetracycline and erythromycin resistance among clinical isolates of branhamella catarrhalis. | we reviewed tetracycline and erythromycin disk diffusion susceptibility of 457 isolates of branhamella catarrhalis. four isolates were resistant to tetracycline, with mics for two available isolates of 16 micrograms/ml. sixteen isolates were in the moderately susceptible range for erythromycin, with an mic for one available isolate being greater than 8 micrograms/ml. these are the first tetracycline- and (by mic) erythromycin-resistant b. catarrhalis isolates reported from the united states. | 1989 | 2510597 |
| in vitro and in vivo antibacterial activities of bo-1341, a new antipseudomonal cephalosporin. | bo-1341, a new antipseudomonal semisynthetic cephalosporin, was evaluated for in vitro and in vivo antibacterial activities in comparison with ceftazidime, cefotaxime, and cefoperazone. the in vitro activity of bo-1341 was generally superior or comparable to the activities of the reference antibiotics against clinical isolates of the family enterobacteriaceae. bo-1341 was highly active against pseudomonas aeruginosa (mic for 90% of the strains tested, 1.56 micrograms/ml), pseudomonas maltophilia ... | 1989 | 2510590 |
| branhamella catarrhalis infections. | 1989 | 2510484 | |
| mixed bacterial and viral infections are common in children. | acute phase and convalescent sera from 51 pediatric patients who had a documented viral infection and no obvious culture-confirmed bacterial infection such as meningitis, otitis media or urinary tract infection were tested by enzyme immunoassay for antibodies to haemophilus influenzae and branhamella catarrhalis and by the latex agglutination test for pneumococcal antigens to evaluate the frequency of mixed bacterial and viral infections. a mixed bacterial and viral infection was documented in 1 ... | 1989 | 2510121 |
| a note on susceptibility of branhamella catarrhalis to heavy metals. | the susceptibility of 56 strains of branhamella catarrhalis and ten neisseria spp. to arsenate, silver, nickel, mercury, lead, cadmium, chromium, manganese, iron, cobalt and molybdenum was tested with an agar dilution technique. all but two strains of b. catarrhalis were resistant to multiple metal ions. there were not sufficient differences in susceptibility, however, to allow the development of a typing scheme based on resistograms. heavy metal resistance in branhamella was unrelated to beta-l ... | 1989 | 2509410 |
| respiratory symptoms due to branhamella catarrhalis and other neisseria species infections--response to erythromycin therapy. | neisseria microorganisms (neisseria lactamica, neisseria sicca, and neisseria mucosa) are regarded as normal respiratory commensals. branhamella catarrhalis (formerly neisseria catarrhalis) has also been regarded as a normal respiratory commensal, but reports indicate that it can be pathogenic. the role of neisseria spp was studied in 160 patients with chest infections and symptoms and signs of obstructive respiratory disease. group i patients (n = 140) had a history of asthma, bronchitis, and e ... | 1989 | 2509070 |
| [nosocomial pulmonary infections caused by branhamella catarrhalis in intensive care units]. | branhamella catarrhalis, a normal inhabitant of the human nasopharynx, is an opportunistic agent that usually infects patients with underlying diseases. b. catarrhalis has become increasingly recognized as an important respiratory pathogen. from november 1985 to february 1988 we have diagnosed four b. catarrhalis nosocomial pulmonary infections in the adult pulmonary intensive care unit (icu) and eight in the pediatric icu. the origin of the contamination has remained unproven because of the lac ... | 1989 | 2508505 |
| branhamella catarrhalis pneumonia with bacteremia. | a woman with diabetes mellitus and coronary artery disease developed pneumonia and bacteremia from branhamella catarrhalis. this is only the fifth reported case of pneumonia with bacteremia due to this organism, which was previously considered normal upper airway flora. | 1989 | 2508240 |
| branhamella catarrhalis bronchopulmonary isolates in picu patients. | branhamella catarrhalis is commonly considered a respiratory commensal but has recently been implicated as a pathogen, particularly in adults. over a 28 month period, b. catarrhalis was isolated from bronchopulmonary secretions of 14 picu patients with acute respiratory infections. twelve patients had pneumonia and two had tracheitis. the mean age was 3.5 years. seven patients had chronic cardiopulmonary disease including two who were immunosuppressed. three had an acute underlying condition and ... | 1989 | 2508048 |
| branhamella catarrhalis pneumonia: report of 4 cases. | this is the first time branhamella catarrhalis has been identified as a lower respiratory tract pathogen in taiwan. all 4 patients with b. catarrhalis pneumonia reported herein had a certain degree of underlying pulmonary dysfunction. two patients had pure b. catarrhalis infection, whilst the other two had concomitant infections with haemophilus influenzae or viridans streptococci. amongst the 3 strains of b. catarrhalis examined, all were capable of producing beta-lactamase. by using the kirby- ... | 1989 | 2507737 |
| [branhamella catarrhalis--a pathogen or an innocent bystander]. | 1989 | 2507424 | |
| effect of age on adherence of branhamella catarrhalis to buccal epithelial cells. | the role of adherence in the pathogenicity of branhamella catarrhalis in lower respiratory tract infection in the elderly was investigated. differential adherence of this organism to buccal epithelial cells of elderly inpatients, outpatients, and young controls was measured. the mean number of bacteria adherent per cell was 36.9 +/- 11.2, 40.2 +/- 6.1 and 16.5 +/- 12.8 for inpatient and outpatient elderly and young controls respectively (significantly different p less than 0.01, student's t test ... | 1989 | 2507402 |
| [branhamella catarrhalis in respiratory infections]. | given the increasing interest that branhamella catarrhalis is acquiring as a possible pathogen of the respiratory tract, we have studied 81 sputum samples of patients with respiratory problems with the aim of evaluating its clinical significance. in 22 of these patients (27.2%) the implication of b. catarrhalis could be established, either as a primary pathogen (40.9%) or in association with other pathogens, especially with haemophilus influenzae (36.4%). chronic bronchitis and bronchopneumonia ... | 1989 | 2506614 |
| [in vitro activity of miocamycin compared with four other macrolides and with pristinamycin against branhamella catarrhalis]. | the in vitro antibacterial activity of miocamycin was compared with four other macrolides (erythromycin, roxithromycin, josamycin, spiramycin) and pristinamycin against 90 clinical isolates of branhamella catarrhalis by determination of minimum inhibitory concentrations. sixty three strains were producing penicillinase. fourteen carbons macrolides and pristinamycin are more effective than sixteen carbons macrolides. in this group, miocamycin have the best activity. there were no significant diff ... | 1989 | 2506513 |
| [in vitro comparative activity of five macrolides against 190 branhamella catarrhalis strains]. | we compared the in vitro activity of 5 macrolides against 190 strains of branhamella catarrhalis; 48 strains were isolated at centre hospitalier, aix-en-provence, the 142 others were isolated during 1987, in 15 different centres-hospitaliers-généraux in france. 153 strains were betalactamase producing strains; no difference in susceptibility to erythromycin was observed on betalactamase producing and non producing strains. three active macrolides against 100% of strains were: erythromycin (mic 5 ... | 1989 | 2506512 |
| [respiratory tract infections caused by branhamella catarrhalis in outpatients with pneumoconiosis]. | to investigate the occurrence of branhamella catarrhalis respiratory tract infections in 109 outpatients with pneumoconiosis, clinical and bacteriological studies were performed during a 4-year period from april 1984 to march 1988. b. catarrhalis was isolated in 26 patients; only three of these received continuous corticosteroid treatment. the incidence of b. catarrhalis respiratory tract infections increased gradually during the years 1984-1986, but decreased for the first time in 1987 compared ... | 1989 | 2506294 |
| [clinical studies on the secondary bacterial infection in respiratory syncytial virus infection of children]. | secondary bacterial infection was studied on 231 children admitted with respiratory syncytial virus (rsv) infection in the 10 years since 1987. of the 231 children, 56 (24.2%) had dual bacterial infection possibly due to secondary bacterial invasion. the diagnoses of bacterial disease were sepsis (2), pyothorax (2), pneumonias (41), otitis media (7), nasopharyngitis (2) and urinary tract infection (2). dual bacterial infections were more frequent in infants and children over 6 months than in inf ... | 1989 | 2504838 |
| branhamella keratoconjunctivitis. | a young male complained of monocular diplopia for over a year. ophthalmic evaluation revealed gross corneal pannus in both eyes and clinical findings precipitated treatment for chronic chlamydial eye disease. the definitive pathogen isolated from both eyes was branhamella catarrhalis. a cause of otitis media, sinusitis, and lower respiratory infections, branhamella is a rare, opportunistic ocular pathogen which may be associated with meibomian gland dysfunction. | 1989 | 2504803 |
| antimicrobial activity of ro 23-9424, a novel ester-linked codrug of fleroxacin and desacetylcefotaxime. | ro 23-9424 is a novel ester-linked codrug of fleroxacin (ro 23-6240; am-833) and the cefotaxime metabolite desacetylcefotaxime. its potency was determined against over 1,000 organisms and found to be intermediate between those of the two components. more than 99% of members of the family enterobacteriaceae were inhibited by greater than or equal micrograms of ro 23-9424 per ml; its mic for 50% of strains tested ranged from greater than or equal to 0.06 to 1 micrograms/ml. staphylococci, streptoc ... | 1989 | 2504106 |
| the role of beta-lactamase in mixed infections in mice in relation to treatment with ampicillin. | beta-lactamase-producing staphylococcus aureus and bacteroides fragilis in a localized mixed infection has been found to degrade the beta-lactam antibiotic at the focus of infection, thus protecting both the bacteria and pathogens susceptible to the antibiotic. to determine if beta-lactamase produced by hemophilus influenzae and branhamella catarrhalis have similar importance in mixed infections, a thread infection model in mice was used to evaluate the capacity of beta-lactamase produced by s. ... | 1989 | 2503565 |
| susceptibility of branhamella catarrhalis to tetracyclines. | 1989 | 2503485 | |
| clinical and bacteriologic features of chronic sinusitis in children. | the clinical and bacteriologic aspects of chronic sinusitis in childhood were studied. of 35 children who underwent surgical procedures for chronic sinusitis, 22 had positive bacteriologic cultures of aspirates from the sinus. the most common organisms isolated were haemophilus influenzae, streptococcus pneumoniae, and branhamella catarrhalis. five of eight s pneumoniae strains were relatively resistant to penicillin and resistant to sulfamethoxazole-trimethoprim. all of the b catarrhalis and 20 ... | 1989 | 2502908 |
| identification of branhamella catarrhalis in 2.5 min with an indoxyl butyrate strip test. | branhamella catarrhalis, an occasional cause of human respiratory infections, unlike most other members of the family neisseriaceae, produces a butyrate esterase. this is capable of breaking the ester linkage between butyryl groups and carrier molecules. b. caviae and b. ovis, which are rarely encountered in pathological specimens, also produce butyrate esterase. this property can be used as a rapid test in the identification of b. catarrhalis. the recently reported rapid test for butyrate ester ... | 1989 | 2502561 |
| nasopharyngeal culture with quantitative analysis of pathogenes in chronic otitis media with effusion. effects on pathogen yield of different swabs and transport methods. | the influence of different swabs and transport media on nasopharyngeal culture pathogen recovery has been studied in patients with chronic otitis media with effusion. transport times of less than two hours have been used. protecting the cotton wire swab with a polyethylene shealth to prevent contamination by nasal flora did not have any significant influence either on the recovery of potential pathogens or on the contaminating nasal flora. facilitating a quantitative analysis of the nasopharynge ... | 1989 | 2502161 |
| bacterial pneumonia in patients with human immunodeficiency virus infection. | human immunodeficiency virus (hiv) infection is associated with abnormalities of humoral immunity that result in an increased incidence of bacterial pneumonia. from 2% to 10% of acquired immunodeficiency syndrome (aids)-associated pneumonia is caused by encapsulated bacteria. clinical features are usually typical of community-acquired pneumonia and include fever, productive cough, and chest pain. focal radiographic infiltrates, an elevated wbc count, and mild hypoxemia are commonly observed. str ... | 1989 | 2501846 |
| [role of normal microflora in the throat in inhibition of adherence of pathogenic bacteria to host cells: in vitro competitive adherence between corynebacterium pseudodiphtheriticum and branhamella catarrhalis]. | our previous study showed the occurrence of branhamella catarrhalis (b. catarrhalis) pulmonary infections which varies seasonally. to investigate the role of normal throat microflora in this seasonal variation of the occurrence of b. catarrhalis infection, seventy seven throat cultures were done in 45 patients with chronic pulmonary diseases from january to december in 1985. the isolation rate of corynebacterium species as normal microflora was relatively higher in summer than in winter. therefo ... | 1989 | 2501428 |
| evaluation of restriction endonuclease analysis as an epidemiologic typing system for branhamella catarrhalis. | restriction endonuclease analysis (rea) was evaluated as an epidemiologic typing tool to distinguish branhamella catarrhalis strains. fourteen beta-lactamase-producing strains were collected over a 16-month period at a hospital where a nosocomial outbreak of this organism was previously documented by rea. rea produced 12 distinct patterns which correlated with epidemiologic data. chromosomal rea appears to be a useful technique for distinguishing b. catarrhalis strains. | 1989 | 2501355 |
| phenotypic characteristics of branhamella catarrhalis strains. | isolates of branhamella catarrhalis from 13 patients with pneumonia, 6 patients with tracheobronchitis, and 8 patients who were colonized with the organism were studied with respect to susceptibility to the bactericidal action of normal human serum (nhs), glass slide hemagglutination (ha) of group o human erythrocytes, beta-lactamase production, and susceptibility to selected antimicrobial agents and laboratory drugs. a total of 18 of 27 isolates were serum resistant, 22 of 27 produced ha, and 2 ... | 1989 | 2501353 |
| identification of neisseria spp., haemophilus spp., and other fastidious gram-negative bacteria with the microscan haemophilus-neisseria identification panel. | the haemophilus-neisseria identification (hnid) panel (american microscan, sacramento, calif.) is a 4-h microdilution format system for identification of haemophilus and neisseria spp., branhamella (moraxella) catarrhalis, and gardnerella vaginalis. the hnid panel was evaluated by using 423 clinical isolates and stock strains of these organisms, and hnid identifications were compared with those obtained by conventional methods. in addition, 32 isolates representing six genera not included in the ... | 1989 | 2501351 |
| wound infection caused by branhamella catarrhalis. | branhamella catarrhalis was isolated from sputum, tracheal secretions, and a nonhealing and infected thoracic surgical wound in a 59-year-old woman who had a history of a chronic, interstitial fibrosis and who had undergone an open lung biopsy procedure. the patient's upper respiratory tract was the likely source of the organism. to our knowledge, this is the first report of a wound infection caused by b. catarrhalis. | 1989 | 2501347 |
| b.cat confirm, a rapid test for confirmation of branhamella catarrhalis. | b.cat confirm (scott laboratories, inc., fiskeville, r.i.), a rapid test for detection of tributyrin hydrolysis, was evaluated for its ability to identify strains of branhamella catarrhalis and to differentiate them from neisseria species and related species. on initial testing, b.cat confirm was positive for 65 (96%) of 68 b. catarrhalis strains within 30 min after inoculation. retesting of the remaining three strains resulted in their correct identification. b.cat confirm was negative for all ... | 1989 | 2501344 |
| branhamella catarrhalis as a cause of pneumonia in a patient with miliary tuberculosis. | branhamella catarrhalis is increasingly reported as a cause of pneumonia in the immunocompromised host. the authors here report what they believe to be a unique case of b catarrhalis bronchopneumonia in a patient who had previously acquired miliary tuberculosis. the patient initially responded to medication but died suddenly following a brief episode of febrile illness. at autopsy, several lines of evidence implicated b catarrhalis in the findings. the authors review the literature regarding cas ... | 1989 | 2501241 |
| adenoids and otitis media with effusion: nasopharyngeal flora. | in order to clarify the role of the microflora of the nasopharynx and adenoids as causative factors of otitis media with effusion (ome), bacteriologic species in middle ear effusions (mees), nasopharyngeal smears, and adenoid tissues of children with ome were cultured. the change in the microflora of the nasopharynx after adenoidectomy, and the degree of bacterial agreement between the microflora of the nasopharynx and adenoid tissue were investigated. nasopharyngeal bacterial flora were investi ... | 1989 | 2500860 |
| branhamella catarrhalis bacteremia in children. | two cases of branhamella catarrhalis bacteremia in childhood are presented. the literature is reviewed for this unusual cause of bacteremia. | 1989 | 2500833 |
| comparison of the quadferm+ 2-hr identification system with conventional carbohydrate degradation tests for confirmatory identification of neisseria gonorrhoeae. | the quadferm+ (analytab products, plainview, ny) rapid identification system was evaluated for its ability to identify correctly neisseria gonorhoeae isolates from specimens obtained at a sexually transmitted disease clinic. one hundred eighty-five isolates (115 n. gonorrhoeae, 45 neisseria meningitidis, 16 neisseria species, and nine branhamella catarrhalis; fresh isolates, frozen stock cultures, and cultures referred from local health agencies) were tested with the quadferm+ system and convent ... | 1989 | 2500720 |
| isolation of the outer membrane of branhamella catarrhalis. | the emergence of branhamella catarrhalis as an important human pathogen has stimulated interest in investigations of the outer membrane (om) of the bacterium. in this study, the om of b. catarrhalis was isolated and partially characterized. radiolabelled cells were lysed and fractionated by isopycnic centrifugation in a continuous sucrose gradient. five fractions were identified. fraction a consisted of om fragments of varying density. fractions b and c were om of a discrete density containing s ... | 1989 | 2500575 |
| subacute sinusitis in children. | the bacteriologic characteristics of subacute maxillary sinusitis have not been delineated in the pediatric age group. forty children between the ages of 2 and 12 years with respiratory symptoms for at least 30 but less than 120 days were evaluated. nasal discharge and cough were the most prominent symptoms. common radiographic findings were diffuse opacification and mucosal thickenings. sinus aspiration was performed on 52 sinuses of 40 children. bacterial colony counts greater than or equal to ... | 1989 | 2500511 |
| supersusceptibility to hydrophobic antimicrobial agents and cell surface hydrophobicity in branhamella catarrhalis. | to clarify the cause of the supersusceptibility of branhamella catarrhalis to macrolide antibiotics, which are well-known to be inactive to most gram-negative bacteria, we determined its cell surface hydrophobicity by the partition experiment between water and hydrocarbons. its cell surface was found to be markedly more hydrophobic than that of escherichia coli or pseudomonas aeruginosa cells. this suggested that the outer membrane of b. catarrhalis plays no role as a diffusion barrier towards h ... | 1989 | 2500380 |
| histamine synthesis by respiratory tract micro-organisms: possible role in pathogenicity. | five bacterial species considered to be potential pathogens in acute exacerbations of chronic bronchitis, cystic fibrosis, and pneumonia--branhamella catarrhalis, haemophilus parainfluenzae, pseudomonas aeruginosa, staphylococcus aureus and streptococcus pneumoniae--were evaluated for their potential to synthesise histamine in vitro. bacterial species commonly isolated from infected sputum but generally not considered to be pathogenic--enterobacteriacae, neisseria pharyngis, coagulase negative s ... | 1989 | 2499609 |
| branhamella catarrhalis as a cause of suppurative arthritis. | 1989 | 2497437 | |
| branhamella catarrhalis in lower respiratory tract secretions in adults. | findings in specimens from the lower respiratory tract were reviewed in order to assess the role of branhamella catarrhalis in broncho-pulmonary infections. branhamella catarrhalis was isolated from the first sample of good quality in 68 (6.7%) of 1,016 patients. in 36 there was pure growth, and review of patients charts suggested a diagnosis of branhamella catarrhalis pneumonia in 12 cases. | 1989 | 2497001 |
| in vitro activity of cefpodoxime proxetil (u-76,252; cs-807) against clinical isolates of branhamella catarrhalis. | cefpodoxime proxetil (u-76,252; cs-807) is a new esterified oral cephem antibiotic with a broad antibacterial spectrum. since data regarding the activity of cefpodoxime against branhamella catarrhalis are limited, we tested its activity against 200 b. catarrhalis isolates. the drug was highly active against beta-lactamase-negative and -positive isolates; 99% of all strains tested showed a cefpodoxime proxetil mic of less than or equal to 2.0 micrograms/ml. | 1989 | 2496654 |
| pneumonia due to moraxella (branhamella) catarrhalis. | branhamella catarrhalis is a neisseriae-like organism that is the newest member of the family of pneumonic pathogens. the organism is seasonal, encountered only during the respiratory disease season. the majority of patients with pneumonia (80% to 90%) have underlying chronic pulmonary disease, and their clinical illness may be difficult to distinguish from exacerbations of lung disease by other causes. b catarrhalis is the most common bacterial pathogen in this setting after haemophilus influen ... | 1989 | 2496450 |
| tracheitis and supraglottis associated with branhamella catarrhalis and respiratory syncytial virus. | 1989 | 2496395 | |
| branhamella catarrhalis pneumonia in non-immunocompromised pediatric patients: report of three cases and review of the literature. | branhamella catarrhalis (b.c.) is found as a commensal in the upper respiratory tract of a healthy individual. we report three pediatric patients with bronchopneumonia allegedly caused by b. catarrhalis. all of them were intubated and on a mechanical ventilation (following either elective surgery or trauma) while the infection developed. although b. catarrhalis has been thought to be penicillin sensitive, an increased frequency of beta-lactamase producing b. catarrhalis has been noted recently. ... | 1989 | 2496194 |
| symptomatic bacteriuria caused by branhamella catarrhalis. | 1989 | 2496172 | |
| emerging pathogens in nosocomial pneumonia. | the organisms responsible for nosocomial pneumonia are continuously evolving. gram-negative bacilli have become the most common etiologic agents over the past 20 years, and with this evolution has come a better understanding of the pathogenesis of gram-negative bacillary pneumonia. some gram-positive cocci, such as enterococci, group b beta hemolytic streptococci and methicillin-resistant staphylococcus aureus, haven taken on new significance in nosocomial respiratory infections. streptococcus p ... | 1989 | 2495944 |
| acute otitis media and respiratory virus infections. | we studied the association of acute otitis media with different respiratory virus infections in a pediatric department on the basis of epidemics between 1980 and 1985. altogether 4524 cases of acute otitis media were diagnosed. the diagnosis was confirmed by tympanocentesis in 3332 ears. respiratory virus infection was diagnosed during the same period in 989 patients by detecting viral antigen in nasopharyngeal mucus. there was a significant correlation between acute otitis media and respiratory ... | 1989 | 2495520 |
| bacteriology of otitis media with effusion. | a study was undertaken to evaluate the prevalence and antibiotic susceptibility of bacteria present in the middle ear of patients with otitis media with effusion. middle ear effusions (mee), nasopharyngeal and throat swabs were obtained at operation and cultured for aerobic and anaerobic bacteria. two hundred and fifty-nine effusions were obtained from 152 subjects examined. haemophilus influenzae was isolated from 32 (12.3 per cent) effusions, streptococcus pneumoniae from seven (2.7 per cent), ... | 1989 | 2495334 |
| branhamella infections. an increasingly common respiratory illness. | branhamella catarrhalis is an important cause of acute sinusitis and otitis media in children and of acute tracheobronchitis in older persons with underlying chronic lung disease or a suppressed immune system. clinical presentation of b catarrhalis infection varies from a mild, self-limiting disease to severe pneumonia, but most cases are mild to moderate in severity. infection occurs sporadically, and endogenous spread from the oropharynx is the likely mechanism. the keys to diagnosis are a hig ... | 1989 | 2494649 |
| tributyrin hydrolysis for identifying branhamella catarrhalis. | 1989 | 2493488 | |
| branhamella catarrhalis infections. | branhamella (moraxella) catarrhalis is responsible for a significant number of bronchopulmonary infections in adults, as well as otitis media and sinusitis in children. this gram-negative diplococcus is indistinguishable from neisseria gonorrhoeae on gram-stained smear. many strains of the organism produce beta-lactamase and are resistant to the penicillins and other beta-lactam antibiotics. when b. catarrhalis is the probable pathogen, a beta-lactamase-resistant antibiotic is the initial drug o ... | 1989 | 2492736 |
| [current bacteriologic status and therapeutic results in acute otitis media in children aged over 3 months]. | 355 children, 3 months to 15 years old, presenting with acute otitis media, underwent a bacteriological study of otitis exsudate. from november 1985 to september 1987, 162 myringotomy and 149 acute otitis media spontaneously discharging were studied in paris. from october 1981 to september 1987, 62 myringotomy and 46 spontaneously discharging acute otitis were studied in valognes. there was none pathogenic bacterium in respectively 20 and 14% of the samples. two or more pathogenic bacterium were ... | 1989 | 2491709 |
| surface-exposed and antigenically conserved determinants of outer membrane proteins of branhamella catarrhalis. | the outer membrane proteins (omps) of branhamella catarrhalis were studied in an effort to identify surface-exposed determinants that are conserved among strains of the bacterium. aliquots of polyclonal antiserum were absorbed individually by strains of b. catarrhalis. the absorbed antisera were tested in comparison with unabsorbed antiserum in an immunoblot assay against omps of the homologous strain. the absence of a band recognized by antibodies in the absorbed antiserum compared with the una ... | 1989 | 2476393 |
| the envelope structure of branhamella catarrhalis as studied by transmission electron microscopy. | the envelope structure of branhamella catarrhalis was studied by electron microscopy and compared with that of other bacteria of the family neisseriaceae, such as moraxella lacunata subsp. liquefaciens and neisseria gonorrhoeae. negative staining of b. catarrhalis showed a mamilliform surface similar to that of moraxella. on thin sections, the cell wall appeared to be made up of a wavy outer membrane tightly linked to a straight peptidoglycan layer. spicule-like structures protruded from the cel ... | 1988 | 2472827 |
| histamine release from human pulmonary mast cells induced by bacterial antigens. | antigens of four bacteria (staphylococcus aureus, haemophilus influenzae, streptococcus viridans, branhamella catarrhalis) were tested for their ability to release histamine from human pulmonary mast cells recovered by means of bronchoalveolar lavages. for the sake of comparison the action of bacterial antigens on human mesenteric and adenoidal mast cells obtained by enzymatic dispersion of the tissues was studied. bal mast cells released histamine in response to all studied bacterial antigens. ... | 1988 | 2468267 |
| branhamella catarrhalis activates human b lymphocytes following interactions with surface igd and class i major histocompatibility complex antigens. | branhamella catarrhalis initiated dna synthesis in human blood or spleen cells enriched for b lymphocytes but did not activate t-lymphocyte-enriched fractions. monoclonal antibodies were used to determine which b-cell surface molecules were of importance for the activation signal. the addition of monoclonal antibodies reactive with igd, hla class i antigens, and b2-microglobulin to b lymphocyte cultures selectively inhibited the b-lymphocyte response to b. catarrhalis. antibody binding to igd an ... | 1988 | 2449982 |
| spectrum and mode of action of azithromycin (cp-62,993), a new 15-membered-ring macrolide with improved potency against gram-negative organisms. | the macrolide antibiotic azithromycin (cp-62,993; 9-deoxo-9a-methyl-9a-aza-9a-homoerythromycin a; also designated xz-450 [pliva pharmaceuticals, zagreb, yugoslavia]) showed a significant improvement in potency against gram-negative organisms compared with erythromycin while retaining the classic erythromycin spectrum. it was up to four times more potent than erythromycin against haemophilus influenzae and neisseria gonorrhoeae and twofold more potent against branhamella catarrhalis, campylobacte ... | 1987 | 2449865 |
| aetiology of community-acquired pneumonia in hospital treated patients. | from may 1982 a prospective 1-year study of adult patients with community-acquired, radiologically verified, hospital treated pneumonia was performed at the department of infectious diseases, orebro medical center hospital, orebro, sweden. the study included 147 patients with a median age of 71 years. special efforts to diagnose a pneumococcal aetiology were accomplished by antigen detection of the pneumococcal c-polysaccharide (pnc) in sputum and saliva samples and by serological methods for de ... | 1987 | 2447637 |
| analysis of cell division gene ftsz (sulb) from gram-negative and gram-positive bacteria. | the ftsz (sulb) gene of escherichia coli codes for a 40,000-dalton protein that carries out a key step in the cell division pathway. the presence of an ftsz gene protein in other bacterial species was examined by a combination of southern blot and western blot analyses. southern blot analysis of genomic restriction digests revealed that many bacteria, including species from six members of the family enterobacteriaceae and from pseudomonas aeruginosa and agrobacterium tumefaciens, contained seque ... | 1987 | 2432055 |
| therapy of otitis media. | the epidemiology, pathogenesis, diagnosis, complications and sequelae, and therapy of otitis media are reviewed. otitis media is one of the most common infections in infants and children. epidemiologic studies have identified season of the year, bottle versus breast feeding, socioeconomic status, race, sex, and daycare attendance as factors associated with the occurrence of otitis media. the condition is believed to arise secondary to eustachian tube dysfunction in the presence of viral or bacte ... | 1990 | 2406100 |
| oral cephalosporins in perspective. | oral cephalosporins, after 25 years of use, continue to present the clinician with a therapeutic challenge. the older agents have been extensively prescribed for ambulatory adult and pediatric patients with a wide variety of infections caused by gram-positive and some gram-negative organisms. the newer agents, cefaclor, cefuroxime axetil, and cefixime, have increased in vitro activity against beta-lactamase-secreting strains of haemophilus influenzae and branhamella catarrhalis which has made th ... | 1990 | 2405586 |
| comparative in vitro activity of win 57273, a new fluoroquinolone antimicrobial agent. | the in vitro activity of win 57273, a new fluoroquinolone antimicrobial agent, was evaluated against approximately 600 bacterial isolates. the new drug was 4- to 128-fold more active than ciprofloxacin against a broad range of gram-positive organisms, with the new drug inhibiting 90% of strains of each species except enterococcus faecium at concentrations of less than or equal to 0.25 microgram/ml. win 57273 was four- to eightfold less active than ciprofloxacin against many members of the family ... | 1990 | 2393275 |
| [clinical examination of ceftibuten in acute bronchitis]. | clinical evaluation of ceftibuten (cetb, 7432-s) was performed in 20 patients with acute bronchitis. they were consisted of 10 males and 10 females aged from 20 to 80 years old. cetb was given orally in daily dose of 300 mg (18 cases) or 600 mg (2 cases) in three divided portions. the duration of administration was 3 to 14 days. especially they were given for 7 days in 16 cases. a total of 11 strains comprising 4 strains of staphylococcus aureus, 2 strains of beta-streptococcus and 1 strain each ... | 1990 | 2391747 |
| [activity of cefuroxime against bacterial strains isolated from acute otitis media]. | the acute otitis media is a frequent infantile disease and, in 80% of cases, a bacterial strain can be isolated from the otorrhoea. haemophilus influenzae and streptococcus pneumoniae are the two major species isolated from auricular exudate, and represent two thirds of all isolated strains, with the others comprising staphylococcus aureus, branhamella catarrhalis, pseudomonas aeruginosa, enterobacteriaceae and corynebacteria. the treatment of this disease is based principally on beta-lactams (a ... | 1990 | 2367151 |
| in vitro activity of bay v 3522, a new cephalosporin, compared with activities of other agents. | the in vitro activity of bay v 3522, a new aminobenzothiazol cephem, was compared with those of other oral beta-lactams. bay v 3522 displayed high activity against staphylococcus spp. (mics for 90% of strains tested [mic90s], 0.5 micrograms/ml), streptococcus pneumoniae (mic90, 0.06 micrograms/ml), and haemophilus influenzae and branhamella catarrhalis (mic90s, 2 micrograms/ml). there was limited activity against members of the family enterobacteriaceae, with the mic90s being between 4 and great ... | 1990 | 2360820 |
| the microbiology of chronic sinus disease in children with respiratory allergy. | chronic maxillary sinusitis is common in children with respiratory allergy and is associated with increased morbidity. the bacteriology of chronic sinus disease in these children has not been adequately evaluated. between may 1987 and january 1988, 12 children (aged 3 to 9 years), all with documented respiratory allergy and chronic respiratory symptoms consistent with chronic sinusitis (greater than 30 days), were fully evaluated. history, physical examination, complete blood count, nasal smear, ... | 1990 | 2355153 |
| the in-vitro activity of cefpodoxime: a comparison with other oral cephalosporins. | the in-vitro activity of cefpodoxime was studied in 529 clinical isolates and compared with the activity of other oral beta-lactams. amongst the enterobacteriaceae cefpodoxime was very active (mic90 less than or equal to 1 mg/l--other than genera commonly possessing chromosomal beta-lactamases). against these strains cefpodoxime was comparable in activity to cefixime and about eight-fold more active than cefuroxime and 8-16-fold more active than cefaclor and cephalexin. staphylococcus aureus str ... | 1990 | 2351624 |
| decreased absence due to infectious diseases in children at two day care centres over an eight-year interval. | causes of absence were recorded at two day care centres during a seven-month period in 1979/80 and a corresponding period in 1987/88, for 82 and 87 children, respectively. during the eight-year interval absence due to disease decreased from 8.2% to 5.7% of total day-care days. a decrease in epidemic diseases during the eight years was evident. there were no cases of morbilli, parotitis or rubella in 1987/88, following an immunisation programme for these diseases initiated in 1982. an out-break o ... | 1990 | 2349881 |
| [evaluation of imipenem/cilastatin sodium in the treatment of respiratory tract infections]. | imipenem/cilastatin sodium (ipm/cs) was administered to 55 patients with respiratory tract infections (rti). a clinical evaluation of ipm/cs was carried out in 51 patients, 28 with pneumonia, 4 with pulmonary abscess, 1 with pyothorax, 6 with bronchitis, 9 with bronchiectasis, 1 with diffuse panbronchiolitis and 2 with rti with chronic obstructive pulmonary disease, and the clinical efficacy rate was 78.4%. causative organisms were isolated in 23 strains out of 20 patients, such as staphylococcu ... | 1990 | 2348550 |
| [studies on respiratory infections in primary care clinic (ii). distribution and antibiotic sensitivity to 45 agents of bacteria isolated from patients with respiratory infections visiting a doctor in private practice]. | the bacteriology of the isolates from the sputum or the throat swab of patients with respiratory infections visiting a doctor in private practice in sendai city during the period from march in 1988 to february in 1989 was documented, and their sensitivity to 45 antimicrobial agents was determined. of the 568 patients, 514 cases had acute pharyngitis, 8 cases each had acute tonsillitis and acute bronchitis, 7 cases were acute pneumonia, 6 cases had herpangina, 18 cases had hand-foot-mouth disease ... | 1990 | 2335751 |
| epidemiological features and chemotherapy of community-acquired respiratory tract infections. | the epidemiology of community-acquired respiratory tract infections (rti) is reviewed with emphasis on acute pharyngitis, otitis media, sinusitis, epiglottitis and pneumonia. the numerical importance of upper respiratory tract infections is stressed and their economic impact discussed. community-acquired pneumonia, although less common, is a more serious infection with a frequent requirement for hospitalization. the heterogeneous microbial aetiology of rti is stressed, together with the impact t ... | 1990 | 2292531 |
| [susceptibilities of clinical bacterial isolates to antimicrobial agents. a study mainly focused on imipenem. reported by the research group for testing imipenem susceptibility on clinical isolates]. | this study was conducted to investigate susceptibilities of clinical bacterial isolates to imipenem (ipm) and other antibacterial agents at 64 hospital laboratories throughout japan from september to december of 1988. in this study, identification and susceptibility testing were carried out at each laboratory and the tests were performed according to the disk dilution method recommended by nccls in which susceptibilities are classified into "s", "ms", "i" and "r". ipm showed markedly high in vit ... | 1990 | 2287060 |
| a double-blind comparison of low-dose ofloxacin and amoxycillin/clavulanic acid in acute exacerbations of chronic bronchitis. | the efficacy and safety of ofloxacin 400 mg once daily and amoxycillin/clavulanic acid 500/125 mg three times daily were compared in a double-blind manner in patients with an acute exacerbation of chronic bronchitis. of 102 patients enrolled, 95 (93%) could be assessed for effectiveness. treatment success was achieved in 41 (84%) of 49 patients in the ofloxacin group compared with 41 (89%) of 46 patients in the amoxycillin/clavulanic acid group. one patient who received ofloxacin and four patien ... | 1990 | 2286595 |
| ofloxacin concentrations in tissues involved in respiratory tract infections. | the literature on the penetration of ofloxacin from blood to respiratory tissue and secretions in patients is reviewed. in patients with acute purulent exacerbations of chronic bronchitis ofloxacin has a cmax value in sputum of 2.7 mg/l after a 400 mg oral dose, 6.1 mg/l after 600 mg and 6.3 mg/l after 800 mg. penetration from blood to sputum varied from 80 to 100%. the concentration of ofloxacin in bronchial aspirate, 1 to 6 h after a single oral dose of 400 mg, varied between 1.1 and 4.5 mg/l. ... | 1990 | 2286591 |
| role of new cephamycins in the management of obstetric and gynecologic infections. | the results of in vitro and in vivo studies of cefmetazole, a second-generation cephamycin, were reviewed. cefmetazole's spectrum of activity includes clinical coverage of many enterobacteriaceae, staphylococci, streptococci, haemophilus species, pathogenic neisseria organisms, moraxella (branhamella) catarrhalis and anaerobic bacteria. cefmetazole is generally two to eight times more potent than cefoxitin against organisms within their spectra and is most active against staphylococci (minimal i ... | 1990 | 2277375 |
| treatment of community-acquired lower respiratory tract infections with oral cefuroxime axetil. | the subjects were adult hospitalized patients, 12 with pneumonia and eight with acute bronchitis. the patients with pneumonia received 500 mg of cefuroxime orally twice daily and the patients with bronchitis received 250 mg twice daily. treatment lasted for ten days in responsive patients. the pathogens identified in the patients' sputum were streptococcus pneumoniae, klebsiella pneumoniae, haemophilus influenzae, enterobacter aerogenes, staphylococcus aureus, or branhamella catarrhalis. clinica ... | 1990 | 2268866 |
| comparative in vitro activity of the new oral cephalosporin bay v 3522 against aerobic and anaerobic bacteria. | the in vitro activity of the new oral cephalosporin bay v 3522 against 229 aerobic and 330 anaerobic clinical isolates was determined using the agar dilution technique. for comparison, amoxicillin, amoxicillin/clavulanate, cefaclor, cefadroxil, cefuroxime, cephalexin, ciprofloxacin, clindamycin, co-trimoxazole, doxycycline, erythromycin and metronidazole (only anaerobic bacteria) were tested. bay v 3522 was found to have high activity against staphylococcus aureus, staphylococcus epidermidis, en ... | 1990 | 2261923 |
| circulation in italy of beta-lactamase-producing strains within the major groups of bacterial pathogens. | a multicenter study was undertaken in italy to assess the circulation of beta-lactamase-producing organisms and their current incidence within the major groups of bacterial pathogens. almost four thousand strains, all freshly isolated from clinical material, were examined at four centers serving different areas of italy. despite some significant center-to-center differences, this survey documented the occurrence of a large overall circulation of beta-lactamase-producing organisms among clinical ... | 1990 | 2253734 |
| controversies in the treatment of streptococcal pharyngitis. | an increasing number of cases of sore throat caused by group a beta-hemolytic streptococci occur with concomitant colonization by organisms that may "protect" the streptococci through beta-lactamase inactivation of penicillin at the site of infection. the failure of penicillin to eradicate many of these bacteria, which include staphylococcus aureus, haemophilus influenzae, moraxella (branhamella) catarrhalis and a multitude of pharyngeal anaerobes, may help to explain why penicillin is sometimes ... | 1990 | 2244548 |
| [studies on respiratory infections in primary care clinic (iv). antibiotic sensitivity of bacteria isolated from patients with respiratory infections visiting 21 private clinics in the tohoku district of japan]. | we determined the mics of ampicillin, methicillin, cefaclor, cefixime, cefteram, ofloxacin and ciprofloxacin against a total of 1,448 strains from 11 species: 464 strains of staphylococcus aureus, 306 strains of streptococcus pneumoniae, 114 strains of streptococcus pyogenes, 37 strains of branhamella catarrhalis, 329 strains of haemophilus influenzae, 32 strains of escherichia coli, 66 strains of klebsiella pneumoniae, 26 strains of enterobacter cloacae, 20 strains of serratia marcescens, 12 st ... | 1990 | 2243194 |
| [studies on respiratory infections in primary care clinic (iii). distribution of bacteria isolated from patients with respiratory infections visiting 21 private clinics in the tohoku district of japan]. | the bacteriology of the isolates from the throat swab and the sputum respectively of 2,539 patients with respiratory infections visiting 21 private clinics in tohoku district of japan during the period from january to april in 1989 was documented. of the 2,539 patients, 1,694 had an acute upper respiratory infection, 609 had acute bronchitis, 46 had acute pneumonia, 84 had acute exacerbation of chronic respiratory infections and 106 had respiratory infections without diagnosis registered. 1887 ( ... | 1990 | 2243193 |
| [synergy between sulbactam and ampicillin or cefoperazone in antimicrobial activity against beta-lactamase producing microorganisms. results with the use of microdilution broth method]. | antimicrobial activities of sulbactam (sbt) with ampicillin (abpc) or with cefoperazone (cpz), in other words, the effects of sbt, an beta-lactamase inhibitor, against beta-lactamase producing strains of clinical isolates, were studied using microdilution broth method. 1. beta-lactamase producing strains such as staphylococcus aureus, branhamella catarrhalis, haemophilus influenzae, escherichia coli and klebsiella pneumoniae decompose benzylpenicillin (pcg) which is one of substrates of the acid ... | 1990 | 2232151 |
| in vitro activity and beta-lactamase stability of the new oral cephalosporin bay v 3522. | the activity of the new oral cephalosporin bay v 3522 was compared to that of six other beta-lactam agents. bay v 3522 inhibited methicillin-susceptible staphylococcus aureus and staphylococcus epidermidis at less than or equal to 2 micrograms/ml, compared to mics of greater than or equal to 8 micrograms/ml for the other cephalosporins tested. it was more active against streptococcus pyogenes (mic less than or equal to 0.06 microgram/ml) than cefuroxime, cefixime, cephalexin and cefaclor. groups ... | 1990 | 2226499 |