Publications

TitleAbstractYear
Filter
PMID(sorted descending)
Filter
[significance of isolating shigella under epidemiological circumstances]. 19853911318
photochemical modifications of lac repressor: effect of effectors binding on tryptophan photooxidation. 19853911222
monoclonal antibody and liposomes. 20143911220
improving the practice of pediatric patient education: a synthesis and selective review.patient education within the pediatric-care setting can be defined as any combination of planned learning experiences designed to facilitate adaptations of behavior conducive to health. it is directed both toward patients and toward significant adult caretakers in the child's environment. additionally, health promotion and health education outside of the patient-care setting are required to promote child health. these efforts include legislation directed toward environmental hazards as well as c ...20143911198
[digital subtraction angiography (dsa) using fuji computed radiography (fcr)]. 20143911166
[study of the sensitivity of anaerobic bacteria using 2 dilution technics].we studied forty-seven anaerobic strains recovered from blood cultures or pus from deep infections over three months. antibiotic sensitivity was tested using two dilution techniques. for both, a standardized, controlled inoculum was used and strains with known susceptibilities were included. the first method consisted of dilution of antibiotics in schaedler broth and mic determination using microplates. in the second method, dilutions in wilkins-chalgren broth with 1.5 g/l agar and atb-api plate ...19853911155
n-methyl-l-glutamate synthase. 19853911004
refined structure of alkaline phosphatase from escherichia coli at 2.8 a resolution.the structure of alkaline phosphatase from escherichia coli has been determined to 2.8 a resolution. the multiple isomorphous replacement electron density map of the dimer at 3.4 a was substantially improved by molecular symmetry averaging and solvent flattening. from these maps, polypeptide chains of the dimer were built using the published amino acid sequence. stereochemically restrained least-squares refinement of this model against native data, starting with 3.4 a data and extending in steps ...19853910843
[the reliability of clinical, hormonal and ultrasonic examination in the diagnosis of extrauterine pregnancy]. 20143910266
[the royal morocco academy]. 20133910181
determination of nanogram quantities of vanadium in biological material by isotope dilution thermal ionization mass spectrometry with ion counting detection. 19853907412
[the nature of the cyclic course of the epidemiological process in dysentery]. 19853907219
[3-year study of shigellosis epidemic in rwanda, central africa. problems of public health and bacteriological aspects].since 1979, the lakes region (kivu in zaïre, western uganda, rwanda, burundi) has been stricken by a bacillary dysentery epidemic at s. dysenteriae type 1. supposed to be extinct since the 1950s., this bacillus has revealed a very noticeable virulence as well by the number of registered cases (524/100.000 in 1983 at ruhengeri-rwanda) as its fast break through. demographic density (from 400 to 600/km2) has played an important role and has facilitated the transition toward epidemicity. systematic ...19853906345
[ct findings of a case of persistent hyperplastic primary vitreous (phpv)]. 20143906194
changing pattern of resistant shiga bacillus (shigella dysenteriae type 1) and shigella flexneri in bangladesh.shigella dysenteriae type 1 (shiga bacillus) has made a dramatic comeback in bangladesh after 10 years when shigella flexneri was the dominant serogroup. whereas s. flexneri showed little increase in resistance to the commonly used antimicrobial agents--namely, trimethoprim-sulfamethoxazole (tmp-smx) and ampicillin-over the years, s. dysenteriae type 1 underwent rapid changes with regard to sensitivity pattern during the last two years. the first tmp-smx-resistant strain of s. dysenteriae type 1 ...19853905980
comparison of beta enolase and myoglobin as histological markers of rhabdomyosarcoma.a comparative study of beta enolase and myoglobin as markers of muscle differentiation in rhabdomyosarcoma was carried out, using an immunoperoxidase peroxidase antiperoxidase technique. material from 26 cases of childhood rhabdomyosarcoma was studied and subdivided into embryonal and alveolar types. positive cytoplasmic staining for beta enolase was seen in 85% of tumours studied (91% alveolar, 79% embryonal), whereas positive staining for myoglobin was detected in only 69% of tumours (82% alve ...20133905869
interspecific reconstitution of maltose transport and chemotaxis in escherichia coli with maltose-binding protein from various enteric bacteria.in escherichia coli, the periplasmic maltose-binding protein (mbp), the product of the male gene, is the primary recognition component of the transport system for maltose and maltodextrins. it is also the maltose chemoreceptor, in which capacity it interacts with the signal transducer tar (taxis to aspartate and some repellents). in studies of the maltose system in other members of the family enterobacteriaceae, we found that mbp is produced by salmonella typhimurium, klebsiella pneumoniae, ente ...19853905762
characterization of monoclonal antibodies against shiga-like toxin from escherichia coli.three monoclonal antibodies, designated mab 16e6, mab 13c4, and mab 19g8, were produced which recognize shiga-like toxin (slt) from escherichia coli. all three monoclonal antibodies neutralized the cytotoxicity of e. coli slt and were able to immunoprecipitate intact labeled toxin with staphylococcus aureus protein a. the three antibodies were of the g1 heavy and kappa light chain classes. mab 16e6 bound to the b subunit of slt in western blots and also neutralized the lethality of the toxin for ...19853905611
identification and antigenic characterization of virulence-associated, plasmid-coded proteins of shigella spp. and enteroinvasive escherichia coli.seven plasmid-coded polypeptides, designated a through g, were identified by two-dimensional nonequilibrium ph gradient electrophoresis of radiolabeled extracts from minicells of virulent shigella flexneri serotypes 2a and 5 and enteroinvasive escherichia coli o143. these polypeptides were deemed to be products of 140-megadalton (mda) virulence-associated plasmids because they were not synthesized in minicells which were not harboring a 140-mda plasmid or in minicells which were carrying an f la ...19853905608
the pre-thrombotic state. 20143905216
decreased chemiluminescent associated phagocytic response of peripheral blood mononuclear cells to chlamydia trachomatis in patients with hla-b27+ anterior uveitis.the chemiluminescent (cl) associated phagocytic response of peripheral blood monocytes to two serovars of chlamydia trachomatis, shigella flexneri and zymosan was assessed in a group of 26 patients with anterior uveitis (au). hla-b27+ patients with au, when compared to hla-b27- patients with au and appropriate controls, had a significantly decreased cl response to c. trachomatis but no difference between groups in the response to s. flexneri and zymosan. the decreased chemiluminescent (phagocyti ...19853904888
[medical views in the 17th century work of stanisÅ‚aw grodzicki]. 20123904217
[functional status of the small intestine in dysentery sonnei and flexneri]. 19853904028
[transabdominal electronic sector scanning of the prostate]. 20123903306
cyclosporine and partial liver allotransplants in a simplified rat model.we designed a simplified rat model to assess the effects of cyclosporine (csa) on liver transplants. auxiliary liver grafts consisting of 20 per cent of the whole liver were supplied with portal inflow and the bile was drained into the stomach. the cuff technique was used routinely for both end-to-end and end-to-side venous anastomoses. the host liver was totally deprived of portal inflow. two inbred strains of rats, lew and f344, were used for isograft (lew----lew) and allograft (f344----lew). ...19853903301
[cardiovascular system transplantation. 9. development of histocompatibility testing and remedy for graft rejection]. 20143903273
self-evaluation by house officers in a primary care training program.expertise in ambulatory care requires a broad range of knowledge and skills. a modified delphi survey technique was used to delineate diagnoses, management techniques, and procedural skills in seven subspecialty areas necessary for house officers in a primary care internal medicine training program. self-evaluation instruments were developed, and residents were asked to rate their abilities in the seven areas. at entry, the house officers generally had more confidence in their diagnostic abiliti ...20133903161
self-evaluation by house officers in a primary care training program.expertise in ambulatory care requires a broad range of knowledge and skills. a modified delphi survey technique was used to delineate diagnoses, management techniques, and procedural skills in seven subspecialty areas necessary for house officers in a primary care internal medicine training program. self-evaluation instruments were developed, and residents were asked to rate their abilities in the seven areas. at entry, the house officers generally had more confidence in their diagnostic abiliti ...20133903161
susceptibility and hla-b27 in post-dysenteric arthropathies.a recent outbreak of bacillary dysentery in the netherlands revealed that, despite the close association of hla-b27 with post-dysenteric or reactive arthritis (rea), not even in one family did all hla-b27 positive patients infected by an arthritogenic bacterium, develop rea. this dissociation shows that additional factors beside b27 may determine susceptibility to rea.19853902627
localization and synthesis of the tumor protein oncomodulin in extraembryonic tissues of the fetal rat.the calcium-binding protein oncomodulin, previously found only in tumors, has been detected during rat development. specific antisera to purified rat hepatoma oncomodulin (mw 11,500) were used to detect oncomodulin by radioimmunoassay (ria) and by avidin-biotin-peroxidase complex (abc) immunohistochemistry. using ria, oncomodulin was found to increase in placenta from below the limits of detection (2 ng/mg protein) on day 13 to approximately 25 ng/mg on day 16 of pregnancy, and to remain high th ...19853902538
sensitivity to bile salts of shigella flexneri sublethally heat stressed in buffer or broth.batch cultures of shigella flexneri m4243 were grown at 37 degrees c in broth to early stationary phase, washed, and heated at 50 degrees c in 0.1 m phosphate buffer (ph 7.0). cells were surface plated on a tryptic phytone glucose agar (tpga), tpga with 0.15 or 0.85% bile salts no. 3 (tpga-bs 0.15 or tpga-bs 0.85), or tpga with 0.25 or 0.50% sodium deoxycholate (tpga-dc 0.25 or tpga-dc 0.50). cells sampled after no heating produced colony counts on tpga-bs 0.85 or on tpga-dc 0.50 that were no mo ...19853901919
[effectiveness of thymalin and prodigiozan in the complex treatment of patients with dysentery]. 19853901509
differentiation of disease recurrence in various primary malignancies using cea slope analysis.cea slope analysis was performed for patients with various primary malignancies who developed recurrent disease. in 340 cases cea slopes could be calculated, and in 289 cases correlated with distinct diagnosis of recurrent disease. local recurrence showed a slope range of 0.02-15.2 micrograms cea increase/l serum/10 days (median = 0.28) and metastatic spread a slope range of 0.03-456 micrograms cea increase/l serum/10 days (median = 0.98). subgroups of patients with metastatic spread to the live ...20123901225
comparative biology of intracellular parasitism. 19853900672
[functional status of monocytes of the peripheral blood in dysentery]. 19853900573
shigellosis (antibiotic resistance and transfer of r-factor). 19853900357
hla-b27 and clinical aspects of ankylosing spondylitis: results of prospective studies. 19853899917
four cases of shigella septicemia in israel.four cases of shigella septicemia are presented. in two children infection was caused by shigella flexneri and in two adults, who had underlying diseases which caused immunosuppression, by shigella sonnei and shigella schmitzi. all four patients responded to intravenous antibiotic therapy. in one patient the organism persisted in the stool, but was eliminated after oral administration of chloramphenicol. shigella septicemia is not uncommon and blood cultures should be obtained in suspected cases ...19853899637
[interrelation of erythropoiesis and lymphopoiesis in experimental infectious processes and in viral leukemogenesis].interrelation of erythropoiesis and immune response was studied in mice of various lines infected with mycoplasma species, shigella flexneri 2a and rauscher leukemia virus (r-mlv). intensity of erythropoiesis was estimated by the endocolonization data of sublethally irradiated mice and 59fe incorporation, while immune reactivity--by generation of splenic antibody-forming cells in response to immunization with sheep erythrocytes. the inverse correlation between the ability of infectious agents to ...19853899611
plasmid-mediated drug resistance of shigellae in kuwait.of 153 clinical isolates of shigellae examined, 64.7% belonged to shigella flexneri, 18.9% to sh. sonnei, 11.8% to sh. boydii and 4.6% to sh. dysenteriae. part of these isolates were resistant to sulfamethoxazole and streptomycin (88.2% each), ampicillin (66.7%), tetracycline (63.4%) and co-trimoxazole (43.1%), with levels of resistance (mic50 and mic90) being invariably high. resistance to three or more drugs (multidrug resistance) was seen in 77.8% of the isolates. all the 25 strains examined ...19853899007
[structural characteristics of the remote interaction of shigella and salmonella with enterocytes of experimental animals].the electron-microscopic analysis of the adhesion of shigella and salmonella nonfimbriated strains to the surface of enterocytes of laboratory animals in vivo and in vitro has revealed the presence of structural links, whose formation occurs with the participation of the glycocalix of the interacting cells and the extracellular gel.19853898674
speech and psychopathology. 20143897749
[acute alithiasic cholecystitis caused by infectious gastroenteritis]. 19853897740
radiation of hiroshima and nagasaki builds foundation for risk estimates. 20113897479
new techniques for the mass spectrometry of natural products. 20143896991
a marker of early amacrine cell development in rat retina.a monoclonal antibody, hpc-1, labels only amacrine and displaced amacrine cells in adult rat retina. reactivity with displaced amacrine cells was demonstrated by double-label immunofluorescence with hpc-1 and ganglion cell-specific reagents. hpc-1 antibody reacts with a polypeptide of apparent molecular weight 35,000. hpc-1 antibody labels migrating amacrine cells in late embryonic retinas. the results define cell-specific gene expression in relation to migration of one subclass of cns neurons.19853896407
neonatal shigellosis with bowel perforation. 19853895181
current diagnosis of infective endocarditis.an analysis was made of 91 cases of infective endocarditis (ie) with regard to causative organisms and their sensitivities to various antibiotics, the clinical features of the disease, the laboratory test results and other items were important in establishing a diagnosis of ie. the number of cases of ie has shown a tendency to increase in recent years, particularly in the number of elderly patients, and the ratio of total cases consisting of prosthetic valve endocarditis (pve) has shown a sharp ...19853894710
urinary retention due to a müllerian duct cyst: role of ultrasonically guided fine needle aspiration in the diagnosis and treatment. 20143894701
humoral response of the mouse to treponema pallidum.to investigate the development of the humoral immune response of mice to infection with treponema pallidum, balb/c and c57bl mice were injected intradermally with 10 x 10(6) virulent organisms. serum samples were taken from the mice at weekly intervals after infection and used in the electrophoretic transblotting technique to detect t pallidum and t phagedenis biotype reiter antigens. the serum samples taken from infected mice at 21, 42, 84, and 126 days after infection recognised two to 15 t pa ...19853894212
obstetric medication and neonatal behavior. current controversies.this article reviews the work on the neonatal effects of low drug doses published in the last five years. at the same time, there will be a focus on new developments in perinatal pharmacology and on current controversies in this area. the article includes discussions about neurobehavioral outcome measures and statistics, as well as recommendations for future studies.20133893844
obstetric medication and neonatal behavior. current controversies.this article reviews the work on the neonatal effects of low drug doses published in the last five years. at the same time, there will be a focus on new developments in perinatal pharmacology and on current controversies in this area. the article includes discussions about neurobehavioral outcome measures and statistics, as well as recommendations for future studies.20133893844
marrow transplantation for children in first remission of acute nonlymphoblastic leukemia: an update.thirty-eight children between the ages of 0.8 and 17 years with acute nonlymphoblastic leukemia in first remission induced by chemotherapy were given cyclophosphamide, total body irradiation, and bone marrow transplants from hla-matched donors. six patients died of pneumonia, one died of metabolic problems, and one died of chronic graft-v-host disease complications. five patients relapsed between six months and 3.2 years after transplantation. three of the five died of leukemia, one survives wit ...20113893570
[possible production of 2 cytotoxins by a strain of escherichia coli]. 19853893462
isotope dilution assay for biotin. 20143893282
william osler: then and now. 20143893123
[detection of shigella antigens in the feces of patients with acute intestinal diseases using a coagglutination reaction].a total of 113 patients with acute intestinal diseases have been examined with the use of the coagglutination test. 84.95% of the patients showed the presence of different shigella antigens. in patients with bacteriologically confirmed dysentery the corresponding shigella antigens were detected in 96.97% of cases in s. sonnei dysentery, in 90% of cases in s. flexneri dysentery, in 75% of cases in s. newcastle dysentery and in 100% of bases in s. boydii dysentery. in 81.6% of patients with acute ...19853892986
[clinical observations during an epidemic caused by shigella flexneri]. 19853892312
[bacillary dysentery in utrecht: 2 epidemics]. 19853892311
[5 cases of reactive arthritis following a shigella flexneri epidemic in the netherlands]. 19853892310
[antibiotic resistance in the isolates of shigella flexneri type 2 associated with the "shrimp epidemic"]. 19853892309
[the shigella flexneri epidemic of 1983/84: the lesson to be learned from this]. 19853892308
[shigella serotypes isolated july-october 1983 and their antibiotic sensitivity].twenty four strains of shigella were isolated from the stool of patients who had been admitted to the hospital with the complaint of diarrhea. of these, 17 were found to be sh. flexneri, and 7 sh. boydii. antibiotic susceptibility tests indicated that all of the 24 isolates probably had multiple resistance factors. twenty three of 24 strains were found to be resistant to ampicillin. this may be important from a therapeutic point of view.19853892249
[intensified conventional insulin therapy--a particular task of the specialty clinic]. 20143891563
survival of bacterial enteropathogens in the ice of popular drinks.we examined the survival of four bacterial enteropathogens frozen in ice and subsequently allowed to melt in various popular drinks. the counts of all the organisms were markedly lowered by freezing alone, and the numbers were further decreased by exposure to some of the drinks. nevertheless, none of the organisms were completely eliminated as a result of freezing for 24 hours followed by melting in any of the test drinks, even when the drink was 86-proof tequila.19853889393
erythema nodosum associated with shigella colitis. 19853888122
perturbation of insulin oscillations by nerve blockade in the in vitro canine pancreas.the in vitro canine pancreas produces an oscillatory pattern of insulin secretion during a constant glucose concentration despite the lack of external nervous modulation or recirculating hormone feedback. the normal period of insulin fluctuations (7.4 +/- 0.34 min) is unaffected by combined adrenergic and cholinergic blockade by 5 microm atropine, 4 microm propranolol, and 4 microm phentolamine (8.0 +/- 0.31 min, p less than 0.20). to test the theory that the coordination of islet secretion may ...19853887939
diagnosis and management of renal angiomyolipoma.renal angiomyolipoma (hamartoma) is an uncommon benign tumor of the kidney. although about 400 cases of renal angiomyolipoma have been reported, it still causes difficulties in diagnosis and treatment. until a few years ago it was almost impossible to arrive at a correct diagnosis preoperatively, and most of the cases underwent nephrectomy with the wrong diagnosis of renal carcinoma. more recently, abdominal computerized tomography and renal sonography have made it possible to reach the correct ...20123887727
sequential bilateral lung transplantation for paraquat poisoning. a case report. the toronto lung transplant group.a 31-year-old nurseryman developed progressive respiratory failure secondary to paraquat poisoning after repeated and prolonged exposure. ventilatory assistance proved inadequate to maintain satisfactory oxygenation, and extracorporeal membrane oxygenator support was instituted. a right lung transplantation was performed, but the transplant subsequently was damaged when lethal levels of paraquat entered the bloodstream from muscle reservoirs. membrane oxygenation was reinstituted for 19 days dur ...20143887042
[diagnosis and documentation of biliary calculi]. 20143887025
studies of metabolites in diarrheal stool specimens containing shigella species by frequency-pulsed electron capture gas-liquid chromatography.eleven diarrheal stool specimens and 10 control stool specimens from cairo, egypt, were studied by frequency-pulsed electron capture gas-liquid chromatography (fpec-glc). four cases involving shigella sonnei, three cases involving shigella boydii, and four cases involving shigella flexneri were studied. the aqueous stools were centrifuged, extracted with organic solvents, and derivatized to form specific electron-capturing derivatives of carboxylic acids, alcohols, hydroxy acids, and amines. ana ...19853886695
effect of temperature on the circular dichroism spectra of beta 2-microglobulins.when the temperature was lowered from 25 to 5 degrees c dramatic changes were observed in the near-ultraviolet circular dichroism spectra of bovine and caprine but not human beta 2-microglobulin. comparison of the protein sequences suggests that the conformational change occurs in the amino-terminal 24 residues and that a tyrosine residue located on a potential beta-turn acts as a reporter group. because delta h degrees is small (-22 kcal x mol-1), such conformational changes, possibly not readi ...19853886425
shigella flexneri bacteraemia.shigellosis is usually a non-invasive enteric disease, rarely accompanied by extra-intestinal manifestations. shigella septicaemia is therefore reported in a child aged 10 months. in the laboratory the organism was resistant to ampicillin and only moderately susceptible to chloramphenicol. the patient responded well to cotrimoxazole to which the organism isolated was susceptible in vitro. we recommend that blood as well as faeces should be cultured in exceptionally ill patients with suspected or ...19853884717
cloning the gene for congo red binding in shigella flexneri.the ability to bind the dye congo red from agar medium is associated with virulence of shigella species. dna sequences conferring this property have been cloned from a large, 140-kilobase plasmid of shigella flexneri into a plasmid vector. this recombinant plasmid does not fully restore virulence to s. flexneri isolates which have lost the large plasmid. this indicates that other genes present on the 140-kilobase plasmid must also be required for virulence of s. flexneri. the cloned fragment con ...19853884508
plaque formation by virulent shigella flexneri.an in vitro tissue culture plaque assay was developed to investigate the intracellular replication and intercellular spread of virulent shigellae. shigella plaques were formed in hela cell monolayers in the presence of an agarose overlay containing tissue culture medium and gentamicin, which eliminated extracellular bacterial growth. microscopically, the plaques were characterized by a central area of dead host cells surrounded by cells infected with shigellae. cells further away from the plaque ...19853884506
rabbit antisera against three different bacteria which can induce reactive arthritis: analysis by elisa, immunoprecipitation and western blot.three strains of bacteria which induce reactive arthritis were collected: a shigella flexneri, designated 7060; another sh. flexneri, designated 316; and a yersinia enterocolitica of serotype 03. rabbit antisera were generated against each of them to test for the extent and nature of cross-reactivity among these strains. when analysed by the elisa technique, antisera against 7060 and 316 showed strong cross-reactivity with y. enterocolitica. in contrast, the reaction of antisera prepared against ...19853884493
smallpox in australia. 20123883104
fatal fungemia with arthritic involvement caused by trichosporon beigelii in a bone marrow transplant recipient. 19853882853
evidence for proctolin-like substances in the central nervous system of the leech hirudo medicinalis.the distribution of proctolin-like immunoreactive (pli) cells was mapped in the central nervous system of the leech hirudo medicinalis. in segmental ganglia, pli cells can be divided into two groups: cells that stain repeatedly in every successive ganglion, and cells that stain only in specific segmental ganglia. the number of pli cells, therefore, ranged from eight to 20 cells per ganglion. one bilateral pair of pli cells (cells pli-1) was further characterized morphologically by lucifer yellow ...19853882776
vesicles and cisternae in the trans golgi apparatus of human fibroblasts are acidic compartments.recently we demonstrated that low-ph compartments can be visualized with the electron microscope using a basic congener of dinitrophenol, 3-(2,4-dinitroanilino)-3'-amino-n-methyldipropylamine (damp), which concentrates in acidic compartments and can be detected by immunocytochemistry with a monoclonal anti-dinitrophenol antibody. we now report that damp also accumulates in cisternae and vesicles associated with the trans face of the golgi apparatus. damp rapidly leaves this compartment when cell ...19853882239
an animal model of haemolytic--uraemic syndrome in shigellosis: lipopolysaccharides of shigella dysenteriae i and s. flexneri produce leucocyte-mediated renal cortical necrosis in rabbits.to develop an animal model of the haemolytic-uraemic syndrome during shigellosis, rabbits were injected with lipopolysaccharides (lps) extracted by the hot phenol-water method from shigella dysenteriae i and from s. flexneri. two intravenous injections of lps spaced by 24 h elicited renal cortical necrosis in a generalized shwartzman reaction characterized by fibrin deposition in glomerular capillaries and by elevated plasma creatinine concentration. rabbits rendered leucopenic by busulphan trea ...19853882120
cranial ultrasound and clinical studies in preterm infants.serial ultrasound imaging of the brain was used to determine the ventricular index (vi), and the ratio (vr) of the vi to the cranial hemidiameter during the nursery course and first year post-term in preterm infants of less than 33 weeks gestation. twenty-nine of the infant survivors with no intracranial hemorrhage or major medical complication during their nursery course composed group 1. twenty-two survivors with intracranial hemorrhage unassociated with early ventricular dilation composed gro ...20133881581
effect of antigen form on local immunoglobulin a memory response of intestinal secretions to shigella flexneri.an enhanced memory response, as shown by increased titers of specific immunoglobulin a (iga), was seen in intestinal secretions from isolated thiry-vella loops in rabbits primed orally with live, locally invasive shigella sp. x16 and challenged 60 days later with a single oral dose of the same antigen. heat-killed shigella preparations, when used as either the priming or challenge antigen, did not elicit such a memory response in this system. in the present study, the role of antigen form and do ...19853880720
effect of octanoate on blood-brain barrier permeability using l-dopa as a marker.short-chain fatty acid injection into animals produces coma, seizures, and hyperventilation. one mechanism of coma production may be through alterations in membrane permeability characteristics. the spg histofluorescence technique was used to evaluate changes in blood-brain barrier permeability to injected l-dopa in rats after intraperitoneal injections of the short-chain fatty acid, sodium octanoate. diffusion of intravascular fluorescence was observed around brain capillaries in the octanoate- ...19853880408
effect of octanoate on blood-brain barrier permeability using l-dopa as a marker.short-chain fatty acid injection into animals produces coma, seizures, and hyperventilation. one mechanism of coma production may be through alterations in membrane permeability characteristics. the spg histofluorescence technique was used to evaluate changes in blood-brain barrier permeability to injected l-dopa in rats after intraperitoneal injections of the short-chain fatty acid, sodium octanoate. diffusion of intravascular fluorescence was observed around brain capillaries in the octanoate- ...19853880408
usefulness of postoperative enzymes for diagnosis of perioperative myocardial infarction following aortocoronary bypass. 20133879714
aspartate: 2-oxoglutarate aminotransferase from trichomonas vaginalis. identity of aspartate aminotransferase and aromatic amino acid aminotransferase.aspartate: 2-oxoglutarate aminotransferase from the anaerobic protozoon trichomonas vaginalis was purified to homogeneity and characterized. it is a dimeric protein of overall mr approx. 100000. only a single isoenzyme was found in t. vaginalis. the overall molecular and catalytic properties have features in common with both the vertebrate cytoplasmic and mitochondrial isoenzymes. the purified aspartate aminotransferase from t. vaginalis showed very high rates of activity with aromatic amino aci ...19853879173
atherosclerosis precursors in finnish children and adolescents. i. general description of the cross-sectional study of 1980, and an account of the children's and families' state of health.the paper describes the general outline of a multicentre study on the risk factors of coronary heart disease (chd) and their determinants in children of various ages in different parts of finland. the study was a cross-sectional one, and was carried out in 1980 in five university cities of finland with medical schools and in 12 rural communities in their vicinity. the randomized sample included an equal number of boys and girls, aged 3, 6, 9, 12, 15, and 18 years, and an equal number of urban an ...20133879091
clinical studies with corticotropin releasing factor: implications for the diagnosis and pathophysiology of depression, cushing's disease, and adrenal insufficiency.corticotropin releasing factor (crf) is a 41 amino acid peptide first isolated from sheep hypothalami and thought to be a principal modulator of the hypothalamic-pituitary-adrenal cortical (hpa) axis. we report herein a series of clinical studies with crf in healthy volunteers and in patients with abnormalities in hpa function, including depression, cushing's disease, cushing's syndrome, and addison's disease. our data indicate that crf can be a diagnostic aid in distinguishing various disorders ...19853878972
[introduction of pos: an educational method. practice of auditing and problems in the application of soap]. 20133878425
pathophysiology of the kidney in rats with heymann nephritis.alterations in kidney function were assessed early in the course of heymann nephritis that was induced in rats by immunization with fx1a, an extract prepared from rat kidney cortex. whole kidney and single nephron function were evaluated by clearance and micropuncture techniques. kidney function was studied in stage 1 of heymann nephritis, before the onset of proteinuria, and in stage 2, when antibodies are deposited along the brush border of proximal tubules. although overall kidney function wa ...19853877841
role of the posterior capsule in the prevention of postoperative bacterial endophthalmitis: experimental primate studies and clinical implications.the posterior capsule has an important effect on the risk of postoperative bacterial endophthalmitis. in order to investigate whether the posterior capsule inhibited the spread of infection into the vitreous we performed extracapsular cataract extraction in both eyes of 10 primates. in one eye of each primate the posterior capsule was left intact and in the other eye a large posterior capsulectomy was performed. when the anterior chambers were challenged with equivalent inocula of staphylococcus ...19853877524
the segmental nephrogram. 20133875232
isolation and characterization of epidermal growth factor from human milk.epidermal growth factor (egf) has been purified from human milk. the purification was monitored with a human placental membrane radioreceptor assay using murine salivary epidermal growth factor i (megf i) as a competitive ligand and was achieved exclusively by the use of reverse-phase liquid chromatography (rplc). the sequential use of preparative, semipreparative and analytical rplc on an octylsilica support with solvent systems of different solute selectivity such as pyridine formate, triethyl ...19853874788
antifibrillatory actions of bepridil and butyl-mdi, two intracellular calcium antagonists.the antifibrillatory and electrophysiologic actions of bepridil and butyl-methylenedioxyindene (bu-mdi), two intracellular calcium antagonists, were examined in anesthetized dogs. the administration of bepridil (1.0-10.0 mg/kg i.v.) significantly increased the electrical threshold for ventricular fibrillation determined during unobstructed coronary flow, and was associated with a significant decrease in ventricular excitability and a progressive depression in ventricular myocardial conduction. b ...19853874780
reactivities of neoplastic t cells to human autoantibody and monoclonal antibodies. 19853873778
gastric ulcers after endoscopic sclerosis of esophageal varices.two patients with bleeding esophageal varices underwent endoscopic sclerosis. each developed a gastric ulcer of the fundic mucosa approximately 6-7 cm below the gastro-esophageal junction. it seems probable that these lesions were related to the retrograde flow of sclerosing solution into the venous system which drains the gastric mucosa.20133872322
[dieulafoy disease. a rare cause of upper gastrointestinal hemorrhage]. 20133871983
[dieulafoy disease. a rare cause of upper gastrointestinal hemorrhage]. 20133871983
[adaptation of rhodopseudomonas palustris to changes in atmospheric conditions].the high level of delta-aminolaevulinate synthetase (ala-s) in rhodopseudomonas palustris cells grown under photosynthetic conditions decreased when they were vigorously aerated; moreover, the bacteriochlorophyll synthesis suddenly stopped. when aeration was interrupted, enzymatic level increased notably, but bacteriochlorophyll level did not. chloramphenicol added to cultures when aeration was interrupted did not affect the increase of enzymic level. when it was added as the aeration started, t ...19853870744
Displaying items 5101 - 5200 of 11070