Publications

[late relapses in malaria caused by plasmodium ovale (stephens, 1922)].		1984	6390576
monoclonal antibody identifies circumsporozoite protein of plasmodium malariae and detects a common epitope on plasmodium brasilianum sporozoites.	we produced a hybridoma secreting an immunoglobulin g1 monoclonal antibody against the circumsporozoite protein of the human malaria parasite plasmodium malariae (uganda 1/cdc). the monoclonal antibody produces a circumsporozoite precipitation reaction when incubated with viable sporozoites of p. malariae and reacts at high titers with heat-fixed sporozoites in an indirect immunofluorescent antibody test. using the purified monoclonal antibody and western blot analysis, we identified two polypep ...	1984	6381308
a case of plasmodium ovale malaria acquired in burma.		1983	6227111
a case of plasmodium ovale infection.		1966	5981462
[on a case of malaria due to plasmodium ovale contracted in guinea].		1966	5976369
the transmission of a west african strain of plasmodium ovale by anopheles freeborni and anopheles maculatus.		1966	5917627
a recently isolated west african strain of plasmodium ovale.		1966	5901625
two cases of plasmodium ovale malaria from central thailand.		1969	5824291
plasmodium ovale endemic in ethiopia.		1969	5794462
[does plasmodium ovale exist in madagascar?].		1970	5537812
[plasmodium ovale].		1969	5369086
an analysis of the geographical distribution of plasmodium ovale.	for a long time plasmodium ovale was considered a very rare causal agent of malaria, but recently it has been shown to be a fairly common parasite in africa. the authors analyse all the findings of p. ovale outside tropical africa and describe its distribution. this species is distributed in 2 areas, the first confined to tropical africa and the second to islands in the western pacific. the authors make a medico-geographical analysis of the distribution of p. ovale, and attempt to explain partic ...	1969	5306622
plasmodium ovale in zambia.		1968	5306106
plasmodium ovale infections in the philippines.		1968	5303913
distribution of plasmodium ovale in the eastern, western and northern regions of uganda.		1967	5301742
relapse activity in sporozoite-induced infections with a west african strain of plasmodium ovale.		1971	5131690
malaria due to plasmodium ovale in rhodesia.		1971	5111356
fluorescent antibodies in human malaria, especially in plasmodium ovale.		1966	4961601
malaria due to plasmodium ovale and vivax.		1971	4944666
[plasmodium ovale (stephens 1922)].		1969	4905936
[detection of plasmodium ovale in moscow in a patient infected in melanesia].		1973	4805414
[tertian malaria caused by plasmodium ovale. report of 2 cases].		1974	4411108
plasmodium ovale malaria acquired in viet-nam.	four cases of plasmodium ovale malaria are reported among us servicemen stationed in viet-nam between january 1966 and march 1969. taken together with other cases cited by the authors, these provide strong evidence of the existence (sometimes disputed) of this plasmodium in continental south-east asia.none of the men had served in any other area of endemic malaria and their travel and medical histories suggest that all 4 infections were acquired by mosquito transmission. they constitute only 0.0 ...	1970	4392940
[plasmodium ovale malaria].		1973	4204333
haemostatic alterations in malaria correlate to parasitaemia.	fibrin(ogen) degradation products, platelet counts, antithrombin iii, and the components of the factor viii complex were studied in a total of 80 patients with plasmodium falciparum, plasmodium vivax or plasmodium ovale infections. the haemostatic findings were correlated to the numbers of parasitized erythrocytes and to each other. the results indicate that haemostatic changes in malaria correlate with the degree of parasitaemia. evidence for moderate hyperfibrinolysis was found in patients wit ...	1985	3933596
ultrastructure of human erythrocytes infected with plasmodium ovale.	ultrastructural changes of the human erythrocytes infected with plasmodium ovale were studied, and differences of p. ovale from other human malarial parasites were discussed. four characteristic morphological alterations were observed on the host cells: caveola-vesicle complex, excrescence, nodule, and cytoplasmic cleft. caveola-vesicle complexes consisted of caveolae surrounded by vesicles in an alveolar fashion and were formed along the host cell plasmalemma. similar complexes have been report ...	1986	3728792
ultrastructure of erythrocytic stages of plasmodium ovale in humans.	an electron microscopic study of plasmodium ovale in humans supplied information on the fine structure of erythrocytic trophozoites, presegmenting schizonts and gametocytes. ultrastructural features of p. ovale appeared quite similar to those described in other mammalian malarial parasites. however, some minor structural variations were observed. the parasite was a fairly compact cell of an oval shape. however, occasionally trophozoites had slender cytoplasmic protrusions. ingestion of host cell ...	1986	3728791
infection of chimpanzees with nigerian i/cdc strain of plasmodium ovale.	seven splenectomized chimpanzees were infected with the nigerian i/cdc strain of plasmodium ovale. two of the animals had no history of previous malarial infection whereas three had been infected with p. vivax, one with p. malariae, and one with p. vivax and p. malariae. the two animals with no previous malarial experience had maximum parasitemias of 88,700 and 127,000 per mm3 while the other animals had maximum parasitemias ranging from 10,100 to 60,600 per mm3. anopheles freeborni, an. dirus, ...	1987	3688304
plasmodium ovale infections in natal.		1987	3686286
localization of circumsporozoite protein of plasmodium ovale in midgut oocysts.	circumsporozoite (cs) proteins are the major proteins found on the surface of salivary gland sporozoites and are the protective antigens of several species of malaria parasites. little is known about the distribution of cs proteins in developing oocysts, however. immunoelectron microscopy with protein a-gold and a monoclonal antibody specific for the cs protein of plasmodium ovale was performed to investigate the distribution of cs protein within developing p. ovale oocysts. there was an almost ...	1987	3679537
plasmodium ovale: in vitro development of hepatic stages.	primary cultures of human hepatocytes, a culture-derived clone from the human hepatoma hep g2 line, and cultured rat hepatocytes were inoculated in vitro with plasmodium ovale sporozoites extracted from anopheles stephensi, an. gambiae, and an. dirus mosquitoes. penetration and differentiation of p. ovale sporozoites into trophozoite stage parasites occurred in all three cell types, but with a lower transformation rate in the hep g2 cell line than in the primary cultured hepatocytes. further mat ...	1987	3678445
stage-specific and species-specific antigens of plasmodium vivax and plasmodium ovale defined by monoclonal antibodies.	monoclonal antibodies (mabs) were produced against the asexual blood stages of plasmodium vivax and plasmodium ovale and used to define antigens of plasmodial parasites in an indirect fluorescent antibody assay. the anti-p. vivax mabs produced two distinct patterns in the indirect fluorescent antibody assay. four patterns were found with the anti-p. ovale mabs. species-specific epitopes were defined for p. vivax and p. ovale; epitopes shared among all four species of human malaria parasites were ...	1986	3536743
circumsporozoite protein of the human malaria parasite plasmodium ovale identified with monoclonal antibodies.	monoclonal antibodies (mabs) have been produced against plasmodium ovale sporozoites and used to characterize the circumsporozoite (cs) protein. six mabs were produced, and all were species specific. by using western blot (immunoblot) analysis, three polypeptides were detected: a predominant 51,000-mr polypeptide and two presumed precursor 57,000- and 67,000-mr molecules. the presence of a repeating epitope in the cs protein of p. ovale was demonstrated by using one of the mabs in a single-antib ...	1988	3338845
relapsing malaria infection acquired in kenya.	an american physician-traveler to east africa presented with manifestations of cerebral malaria and was treated with intravenous quinidine for chloroquine-resistant falciparum malaria. he later relapsed with plasmodium ovale infection, despite previous primaquine therapy. treatment of chloroquine-resistant malaria is discussed. the difficulty in diagnosing p. ovale infections and the predominance of this malaria species over p. vivax in east africa are reviewed.	1987	3300055
seven patients with relapses of plasmodium vivax or p. ovale despite primaquine treatment.	seven relapses of plasmodium vivax or plasmodium ovale despite standard treatment with primaquine (3.0 mg kg-1) daily for fourteen days are presented. the majority of patients came from areas outside the countries where resistance to primaquine is well known. the various possibilities of reasons for relapses are discussed.	1987	3299660
concentration of plasmodium ovale- and plasmodium vivax-infected erythrocytes from nonhuman primate blood using percoll gradients.	plasmodium vivax and plasmodium ovale schizont-infected erythrocytes were separated from peripheral blood by centrifugation using discontinuous percoll (colloidal silica) gradients. infected aotus monkey or chimpanzee blood was diluted and placed on a discontinuous gradient containing 30%, 40%, 45%, and 50% percoll (v/v in media) layers before centrifugation at 1,450 x g. parasitized erythrocytes were concentrated to greater than 95% schizont-infected cells in two bands that contained an average ...	1986	3006527
[transfusion malaria caused by plasmodium ovale. a case].		1988	2968562
[anemic plasmodium ovale malaria after 45 months' incubation].		1987	2950492
detection of plasmodium ovale in koraput district, orissa state.	we report for the first time the detection of p. ovale infection in three patients in two hilly villages of koraput district, orissa state, india. the identification of the parasite was confirmed by the imperial colleage of science and technology, london.	1989	2737703
cloning and characterization of an abundant plasmodium knowlesi antigen which cross reacts with gambian sera.	a 110 kda plasmodium knowlesi antigen, termed pk110, has been identified on the basis of messenger rna abundance in late schizonts. most plasmodium genes previously cloned have been identified by immune sera, which have selected immunodominant antigens composed of repeating epitopes. although pk110 was not selected by immune sera, it also contains amino acid repeats, indicating that this structure may be a common feature of malarial proteins. determination of 296 codons in the pk110 gene reveale ...	1987	2444886
[imported malaria at hospitals in bordeaux (france) in 1987 and 1988. report of 185 cases].	100 cases of imported malaria were registered in hospitals of bordeaux in 1987 and 85 in 1988. origin of infestation is africa in 88 p.c. of the cases mainly from central africa (50 p.c.) in 1987 and western africa (67 p.c.) in 1988. the most frequent species was plasmodium falciparum 73 p.c. in 1987 and 82 p.c. in 1988. admitted cases in bordeaux were mainly french (81 p.c.) with a significant male prevailing and young adults. mean age was 29 for europeans and 19 for the others mainly africans. ...	1990	2195286
plasmodium ovale in indonesia.	we report 34 infections by plasmodium ovale found among 15,806 blood film examinations taken between 1973 and 1989 from several sites in indonesia. twenty five of the p. ovale infections occurred in a single sample of 514 people living in owi, irian jaya. we detected five additional infections at 3 other sites in irian jaya. other infections by p. ovale occurred at two sites in west flores. another infection has already been reported from east timor. despite relatively frequent sampling of popul ...	1990	2151542
recurrent plasmodium ovale infection from papua new guinea--chloroquine resistance or inadequate primaquine therapy?		1991	1753151
late plasmodium ovale malaria.		1991	1682724
spontaneous splenic rupture due to plasmodium ovale malaria.		1991	1681259
prophylaxis for malaria. helping world travelers come home healthy.	malaria is largely preventable, so travelers should be taught general protective measures and given appropriate chemoprophylaxis before they leave on their trip. chloroquine phosphate (aralen) is still the drug of choice in locations where malaria remains chloroquine-sensitive. however, chloroquine-resistant areas infested with plasmodium falciparum are becoming more numerous. in such areas, mefloquine hydrochloride (lariam), doxycycline, or proguanil (paludrine) (obtainable outside the united s ...	1992	1518752
plasmodium ovale in the highlands of irian jaya, indonesia.		1992	1449279
plasmodium ovale malaria in canada following transfusion.		1977	912619
[plasmodium ovale malaria in france. probability of of genetic control of the incubation period (author's transl)].	plasmodium ovale as the causative parasite in attacks of malaria is rare. nevertheless, the number of cases seen in france would seem to be on the increase. in 137 attacks of malaria collected between 1967 and 1978, plasmodium ovale was found on 13 occasions. the main characteristics of this form of malaria are, apart from its benign nature, the usual absence of any recurrence and a very variable incubation period, ranging from fifteen days to several months or even a year (with an average of 3. ...	1979	400010
[a case of the imported plasmodium ovale malaria (author's transl)].		1979	112198