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experimental milk-borne transmission of powassan virus in the goat.a lactating goat with a 74-day-old kid was inoculated with 10(3) mouse 50% lethal dose (ld50) of powassan virus. no ensuing viremia could be detected, but virus was secreted in the milk on postinoculation days 7 through 15, with a titer of 10(5) ld50/ml on day 12. neutralizing antibody was found in the serum on days 22 through 36 and in the milk on day 36. the offspring was not inoculated but was allowed to continue feeding on its mother's milk. it developed neutralizing antibody by day 22. sinc ...1977190910
light and electron microscope study of the neurotropism of powassan virus strain p-40.brains of adult white mice inoculated with the p-40 strain of powassan virus isolated in primorsky krai (u.s.s.r) from ticks were studied by light and electron microscopy. accumulations of virus particles were found in neurons and their dendrites and axons, in glial cells, and in intercellular spaces. in the nerve cells, most prevalent were changes of the type of chromatolysis and formation of small vacuoles, associated with the alteration of the endoplasmic reticulum induced by virus morphogene ...197935957
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