Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
|---|
| [a study on transmission of pathogenic bacteria of rampant caries from mothers to children]. | in order to prevent rampant caries in children, the transmission from mothers to children of pathogenic bacteria of rampant caries will be investigated in this study. | 2001 | 12539419 |
| [effects of monoclonal antibody against the major cell surface protein on salivary agglutinin mediated aggregation of streptococcus sobrinus]. | to investigate the effects of monoclonal antibody on salivary agglutinin-mediated aggregation of streptococcus sobrinus in vitro. | 1999 | 12539288 |
| bacteriophage isolation from human saliva. | to detect bacteriophages for gram-positive oral pathogens in human saliva. | 2003 | 12485342 |
| similarity of the oral microbiota of pre-school children with that of their caregivers in a population-based study. | this study evaluated the similarity between the oral microbiota of young children and that of their adult caregivers. oral samples from children (174 dentate and 18 pre-dentate) aged 6-36 months and their caregivers in saipan were assayed using a dna probe assay. many species including streptococcus mutans, streptococcus sobrinus, actinomyces species, campylobacter rectus, fusobacterium nucleatum, prevotella intermedia, and porphyromonas gingivalis were detected in dentate and pre-dentate childr ... | 2002 | 12485330 |
| effects of apigenin and tt-farnesol on glucosyltransferase activity, biofilm viability and caries development in rats. | propolis, a resinous hive product secreted by apis mellifera bees, has been shown to reduce the incidence of dental caries in rats. several compounds, mainly polyphenolics, have been identified in propolis. apigenin and tt-farnesol demonstrated biological activity against mutans streptococci. we determined here their effects, alone or in combination, on glucosyltransferase activity, biofilm viability, and development of caries in rats. sprague-dawley rats were infected with streptococcus sobrinu ... | 2002 | 12485324 |
| real-time pcr for quantification of streptococcus mutans. | a real-time polymerase chain reaction (pcr) assay was developed for the quantification of streptococcus mutans. primers targeting gtf genes of s. mutans were designed and tested for their specificity using 28 oral streptococcal strains, three other bacterial strains, and human dna. the primers could amplify specifically the target dna fragment from a mixture of oral streptococcus genomic dna containing about 10 fg to 10 ng of s. mutans genome dna. the real-time pcr produced a linear quantitative ... | 2002 | 12445641 |
| evaluation of antimicrobial properties of orthodontic composite resins combined with benzalkonium chloride. | an antimicrobial agent, benzalkonium chloride (bac), was added to a chemically cured composite resin, and the antimicrobial benefits and physical properties of the modified composite were evaluated. bac was added to reliance phase ii composite to create modified composites with bac concentrations ranging from 0.25 to 2.50 wt%. specimen disks of the modified composite were incubated with streptococcus mutans for 48 hours, and an agar disk diffusion assay was used to measure zones of bacterial inh ... | 2002 | 12226611 |
| effect of molecular mass and degree of deacetylation of chitosan on adsorption of streptococcus sobrinus 6715 to saliva treated hydroxyapatite. | we evaluated the influence of molecular mass and degree of deacetylation of chitosan on the adsorption of streptococcus sobrinus 6715 to saliva-treated hydroxyapatite (s-ha) by measuring the optical density of the bacterial cell suspensions released from saliva-treated hydroxyapatite. twenty-five chitosan samples with different molecular masses (0.8-6 kda) and degrees of deacetylation (10-95%) were prepared for the study. we found that the inhibition of adsorption of s. sobrinus 6715 to s-ha cor ... | 2002 | 12174667 |
| chemical-biological interactions of naf with three different cell lines and the caries pathogen streptococcus sobrinus. | fluoride is used in dentistry as a prophylactic agent to reduce caries rates due to the demineralization/remineralization effect and its influence on the metabolism of cariogenic bacteria. the purpose of this study was to evaluate the cytotoxic effects of sodium fluoride (naf) on three different cell lines and the antibacterial potency on streptococcus sobrinus. cell lines were treated with various concentrations of naf ranging from 0.039 mm to 10 mm for 24 h. for microbial assays, concentration ... | 2002 | 12166720 |
| [anti-caries vaccines]. | even though the reduction of caries-incidence in developed countries, its increasing has been observed nowadays. the use of a vaccine was object of many researches, going under modifications and evaluations during years. wallace and mccollum showed the chance to induce experimental cavities, while clarke and mcintosh were the first underlining the roll of s. mutans and lactobacilli as efforts of the pathology. williams was the first working with humans and zinner and fitzgerald continued. so sin ... | 2002 | 12147978 |
| the effect of a high-sucrose diet on dentin formation and dental caries in hyperinsulinemic rats. | a high-sucrose diet decreases dentin formation and its minerals, but the mechanisms behind the effect are largely unknown. we studied the combined and separate effects of sucrose and insulin on dentin formation and mineral metabolism in growing rats. at weaning, animals were randomized into 4 groups: control/sucrose diets both with and without external insulin (1 u/x 100 g body weight daily). after 4 weeks, we measured areas of dentin formation, numbers and areas of dentinal caries lesions, and ... | 2002 | 12147743 |
| intracellular and extracellular phs of streptococcus mutans after addition of acids: loading and efflux of a fluorescent ph indicator in streptococcal cells. | a ph-sensitive fluorescent dye, 2', 7'-bis-(2-carboxyethyl)-5 and 6-carboxyfluorescein (bcecf), was used to determine intracellular ph (ph(in)). the efflux of bcecf loaded into oral streptococcal cells was determined after incubation of the cells at 35 degrees c for 20 min in the presence and absence of glucose. in the absence of glucose, the fluorescence of intracellular bcecf in streptococcus mutans, streptococcus sanguis, streptococcus salivarius and streptococcus sobrinus decreased only very ... | 2002 | 12121474 |
| selection of dairy bacterial strains as probiotics for oral health. | the aim of the present study was to select bacterial strains with potential properties as oral probiotics, namely for the prevention of dental caries. we examined 23 dairy microorganisms, out of which we identified two streptococcus thermophilus and two lactcoccus lactis strains that were able to adhere to saliva-coated hydroxyapatite beads to the same extent as streptococcus sobrinus omz176. two of them, strep. thermophilus ncc1561 and lactoc. lactis ssp. lactis ncc2211, were further successful ... | 2002 | 12120707 |
| susceptibility of streptococcus mutans and streptococcus sobrinus to cell wall inhibitors and development of a novel selective medium for s. sobrinus. | representative strains of streptococcus mutans and streptococcus sobrinus showed differences in susceptibility to members of the monobactam group of beta-lactam antibiotics: s. sobrinus was less sensitive than s. mutans. the minimum inhibitory concentrations of aztreonam (azt) and carumonam, both of which belong to this group, were 2,000 microg/ml for s. sobrinus and 125 microg/ml for s. mutans. further addition of fosfomycin, bacitracin and sodium chloride to mitis salivarius agar (ms) suppleme ... | 2002 | 12065966 |
| salivary microbiota levels in relation to periodontal status, experience of caries and miswak use in sudanese adults. | the purpose of the present investigation was to assess the salivary levels of 25 oral bacteria in relation to periodontal status and experience of caries, and to compare the levels of these bacteria between habitual miswak and toothbrush users in adult sudanese subjects. | 2002 | 12060423 |
| an essential amino acid residue for catalytic activity of the dextranase of streptococcus mutans. | dextranase (dex) is an enzyme that hydrolyzes glucan, a polymer of glucose synthesized from sucrose by glucosyltransferases (gtfs). by comparing amino acid sequences of dexs and gtfs, we found that the dex enzymes of streptococcus mutans, streptococcus sobrinus, streptococcus downei and streptococcus salivarius had similar amino acid sequences to those of the catalytic sites of gtfs of mutans streptococci. we therefore examined the amino acid essential in dex catalysis by molecular genetic appro ... | 2002 | 12030973 |
| evaluation of interleukin 1 as a mucosal adjuvant in immunization with streptococcus sobrinus cells by tonsillar application in rabbits. | to evaluate interleukin 1 (il-1) as a mucosal adjuvant in the induction of salivary antibodies to streptococcus sobrinus, s. sobrinus together with il-1 was applied through the palatine tonsils of rabbits. il-1 caused approximately 50 and 100% increases in the antibodies reacting against s. sobrinus fragments in the saliva and blood plasma, respectively, compared to the antibodies in those same fluids after tonsillar applications of s. sobrinus alone. in the case of the addition of il-1, the ant ... | 2002 | 12030968 |
| expression and characterization of streptococcal rgp genes required for rhamnan synthesis in escherichia coli. | six genes (rgpa through rgpf) that were involved in assembling the rhamnose-glucose polysaccharide (rgp) in streptococcus mutans were previously identified (y. yamashita, y. tsukioka, k. tomihisa, y. nakano, and t. koga, j. bacteriol. 180:5803-5807, 1998). the group-specific antigens of lancefield group a, c, and e streptococci and the polysaccharide antigen of streptococcus sobrinus have the same rhamnan backbone as the rgp of s. mutans. escherichia coli harboring plasmid prgp1 containing all s ... | 2002 | 12010977 |
| how xylitol-containing products affect cariogenic bacteria. | the authors examined the effect of xylitol, a naturally occurring sweetener, on levels of streptococcus mutans and s. sobrinus. they also investigated xylitol's mechanism of action. | 2002 | 11991460 |
| pcr detection of streptococcus mutans and s. sobrinus in dental plaque samples from japanese pre-school children. | streptococcus mutans and s. sobrinus are associated with the development of dental caries. these bacteria were detected by pcr and then their presence was compared with the incidence of dental caries in 77 japanese pre-school children. plaque samples were collected from all erupted tooth sites in the subjects, aged 3-5 years old and each with primary dentition, with a sterile toothbrush. a dental examination was performed for dmft (decayed, missing, filled, total) with the who caries diagnostic ... | 2002 | 11990497 |
| cloning and nucleotide sequence analysis of the streptococcus sobrinus gtfu gene that produces a highly branched water-soluble glucan. | streptococcus sobrinus has four gtf genes, gtfi, gtfs, gtft, and gtfu, on the chromosome. these genes correspond respectively to the enzymes gtf-i, gtf-s1, gtf-s2, and gtf-s3. an escherichia coli md66 clone that contained the s. sobrinus gtfu gene was characterized. immunological properties showed that the protein produced by the e. coli md66 clone was similar to s. sobrinus gtf-s1. biological properties and a linkage analysis of the glucans by 13c nmr spectrometry revealed that the protein prod ... | 2002 | 11960691 |
| cariogenic traits in xylitol-resistant and xylitol-sensitive mutans streptococci. | long-term xylitol consumption leads to the emergence of xylitol-resistant (x-r) mutans streptococci. the aim of the present study was to compare cariogenic traits in x-r and xylitol-sensitive (x-s) strains. six strains of mutans streptococci, three x-r and three x-s strains, were studied. xylitol resistance and sensitivity were confirmed by growth in xylitol-supplemented media. acid production from glucose or fructose or uptake of xylitol was initiated by adding (14)c-labelled glucose, fructose ... | 2002 | 11929556 |
| screening of antiadherent activity on streptococcus sobrinus culture. | the mutans group of streptococci is considered to play a key role in the etiology of dental caries. we have evaluated the ability of different substances to prevent dental plaque formation without affecting streptococcus sobrinus viability. viable organisms were detected as cfu/ml in agar plates and bacterial adherence was assessed by dry weight. we studied 23 compounds and we demonstrated that phenyl salicylate, phenylmercuric nitrate and potassium iodate are more effective to inhibit adhesion ... | 1997 | 11885077 |
| bacterial, behavioral and environmental factors associated with early childhood caries. | the goals of this cross-sectional study were to characterize and compare demographic, behavioral, and environmental factors potentially associated with early childhood caries (ecc) and to assess salivary levels of mutans streptococci (ms) and lactobacilli (lb) in underserved, predominantly hispanic children. one hundred forty-six children aged 3 to 55 months with a range of caries experience were identified and examined. ecc was primarily associated with the presence of ms and lack of access to ... | 2002 | 11878278 |
| cariogenicity of different types of milk: an experimental study using animal model. | this study evaluated the cariogenic potential of infant formulas and cow's milk, using a high cariogenic challenge in the animal model. sixty female wistar rats infected with streptococcus sobrinus and desalivated were randomly divided into 6 groups, which received ad libitum: 1) sterilized deionized distilled water (sdw) with 5% sucrose; 2) cow's milk; 3) nan 2; 4) nestogeno 2; 5) ninho growth supporting; 6) sdw. groups 1 and 6 also received essential diet ncp#2 by gavage, twice a day. after 21 ... | 2002 | 11870958 |
| stability and activity of specific antibodies against streptococcus mutans and streptococcus sobrinus in bovine milk fermented with lactobacillus rhamnosus strain gg or treated at ultra-high temperature. | passive local immunization against dental caries is a promising approach to its prevention, as clinical evidence of active oral or nasal immunization is still limited and controversial. by means of systemic immunization of pregnant cows with a multivalent vaccine, high titres of igg antibodies against human cariogenic bacteria, streptococcus mutans and streptococcus sobrinus, were produced in bovine colostrum. the purified immune product (ip) of this preparation has a number of anticariogenic pr ... | 2002 | 11860550 |
| [effect of monoclonal antibody on the colonization of streptococcus sobrinus and the development of dental caries in rats]. | to investigate the effect of local application of monoclonal antibody (mcab) raised against the major cell surface protein antigen of streptococcus sobrinus (pag) on the colonization of rats' teeth by streptococcus sobrinus (s. sobrinus) and the development of dental caries. | 1999 | 11834175 |
| adhesion in vitro of oral streptococci to porcelain, composite resin cement and human enamel. | we investigated the initial adhesion in vitro of oral streptococci to porcelain inlays. four strains of streptococci, streptococcus mitis nctc12261, streptococcus oralis atcc9811, streptococcus sanguis atcc10556 and streptococcus sobrinus omz176, were used in this study. the disc specimens were made of porcelain, composite resin cement and human enamel. these specimens, with or without a saliva-coat, were immersed in a suspension of each streptococci strain at 37 degrees c for 1 hr, and the numb ... | 2000 | 11816366 |
| mutans streptococci--in families and on tooth sites. studies on the distribution, acquisition and persistence using dna fingerprinting. | mutans streptococci (ms) are bacteria showing several cariogenic traits. this thesis is based on the concept that humans acquire ms directly or indirectly from each other. previous research on the transmission of the bacteria in families has indicated that children acquire ms from their mothers. just a few studies have included fathers. diverging results have been presented about spouses acquiring ms from each other. the information on the distribution of ms types at a tooth surface level has be ... | 2001 | 11799837 |
| in vitro evaluation of the antimicrobial activity of a castor oil-based irrigant. | the antimicrobial activity of irrigating solutions--endoquil (castor oil detergent), 2% chlorhexidine gluconate solution, and 0.5% naocl solution-was evaluated against gram-positive cocci (micrococcus luteus, staphylococcus aureus, enterococcus faecalis, staphylococcus epidermidis, streptococcus mutans, and streptococcus sobrinus), gram-negative rods (escherichia coli and pseudomonas aeruginosa), and the yeast candida albicans. activity was evaluated using the two-layer agar diffusion technique. ... | 2001 | 11771574 |
| [experimental study of bacteriostatic activity of chinese herbal medicines on primary cariogenic bacteria in vitro]. | to screen some chinese herbal medicines for their inhibitory activity on cariogenic bacteria, and investigate their active ingredients, and measure their minimum inhibitory concentration (mic), minimum bactericidal concentration (mbc). | 2001 | 11769659 |
| caries inhibition efficacy of an antiplaque/antigingivitis dentifrice. | to evaluate the efficacy of a fluoride dentifrice containing a fixed combination of essential oils (thymol, menthol, eucalyptol, and methyl salicylate) in preventing caries in sprague dawley rats. | 2000 | 11763908 |
| early formation of streptococcus sobrinus biofilm on various dental restorative materials. | to examine the formation of dental biofilm by streptococcus sobrinus on different types of restorative materials, using a model consisting of host and bacterial constituents. | 2002 | 11741735 |
| antibacterial effect of parabens against planktonic and biofilm streptococcus sobrinus. | tooth decay is an infectious disease caused by bacteria immobilized on the tooth surfaces. eradication of these bacteria, for example streptococcus sobrinus (s. sobrinus), from the oral cavity is essential in the prevention and treatment of tooth decay. we have tested the antimicrobial effect of several paraben derivatives such as methyl (mp), ethyl (ep), propyl (pp) and butyl (bp) against immobilized and planktonic s. sobrinus. the antibacterial effect was as follows: mp>ep>pp=bp on immobilized ... | 2001 | 11738348 |
| cariogenic potential of lactosylfructoside as determined by acidogenicity of oral streptococci in vitro and human dental plaque in situ. | the cariogenic potential of lactosylfructoside [o-beta-d-galactopyranosyl-(1-->4)-o-alpha-d-glucopyranosyl-(1<-->2)-beta-d-fructofuranoside] was estimated by experiments on oral streptococci in vitro and human dental plaque in situ. lactosylfructoside was unable to support growth of the strains of streptococcus mutans and s. sobrinus used in this study. however, it was able to support growth of strains of s. sanguis, s. mitis and s. oralis. acid was produced rapidly by cell suspensions of s. ora ... | 2001 | 11641569 |
| the effects of benzoate and fluoride on dental caries in intact and desalivated rats. | the decline in prevalence of dental caries in some segments of the population has been attributed mainly to extensive exposure to fluoride. over the past decades, the use of fluoridated products has increased. during the same period, the consumption of food preservatives such as benzoates and sorbates has also increased substantially. benzoates, in vitro, possess antibacterial properties similar to those of fluoride and in combination with fluoride could affect caries development. in the present ... | 2001 | 11641568 |
| in vitro antimicrobial activities of bakuchiol against oral microorganisms. | bakuchiol was isolated from the seeds of psoralea corylifolia, a tree native to china with various uses in traditional medicine, followed by extraction with ether and column chromatography combined with silica gel and octyldecyl silane. in this study, the antimicrobial activities of bakuchiol against some oral microorganisms were evaluated in vitro. the cell growth of streptococcus mutans was inhibited in a bakuchiol concentration-dependent manner, and growth of s. mutans was completely prevente ... | 2001 | 11600349 |
| induction and 3d reconstruction of caries-like lesions in an experimental dental plaque biofilm model. | the aim of this study was to examine an in vitro dental plaque model for volumetric assessment and 3d reconstruction of experimentally bacterial induced caries-like lesions. twenty-three extracted, impacted human molars were coated with a varnish leaving a 3 x 3 mm window on the smooth surface. the teeth were coated with human saliva and streptococcus sobrinus 6715 adhered onto the enamel via a sucrose dependent mechanism. the coated teeth were incubated for 1, 7, 14 and 28 days. at the end of e ... | 2001 | 11556956 |
| alteration of the coadherence of candida albicans with oral bacteria by dietary sugars. | interactions between bacterial oral flora and candida albicans are important in denture plaque formation. this study therefore first aimed to quantify the coadherence of c. albicans and bacteria by the use of a bioluminescent adenosine triphosphate (atp) assay based on the firefly luciferase-luciferin system. the second aim was to examine the effect of i) dietary sugars (used for preculture) and ii) enzymatic digestion of fungi on the coadherence. when yeast was preincubated in yeast nitrogen ba ... | 2001 | 11555304 |
| adherence of plaque components to different restorative materials. | this study compared the amount of artificial plaque synthesized in vitro by streptococcus sobrinus on various dental materials using radioisotopes. in particular, plaque-retaining capacities of new types of ceramics were the focus of this study. specimens were fabricated from the following materials (one amalgam alloy [spherical-d], one casting gold alloy [casting gold type i], one resin composite [herculite xr] and three ceramics [vita celay blanks, ips empress and dicor mgc]). the amount of ba ... | 2001 | 11504440 |
| bactericidal and cytotoxic effects of sodium hypochlorite and sodium dichloroisocyanurate solutions in vitro. | the antimicrobial and cytotoxic effects of sodium hypochlorite (naocl) and sodium dichloroisocyanurate (nadcc) were evaluated and compared in vitro. the minimal inhibitory concentration and minimal bactericidal concentration of naocl and nadcc were tested for streptococcus sobrinus, streptococcus salivarius, enterococcus faecalis, and streptococcus mutans. the cytotoxic effect was assessed by using human fibroblast tissue culture. survival rate was assessed by a protein determination method. res ... | 2001 | 11485267 |
| does social deprivation in 1, 2, 3 and 4-year-old scottish infants influence the frequency isolation of caries-associated micro-organisms? | the aim of this study was to determine if there are associations between the level of social deprivation/affluence and the frequency isolation of caries-associated micro-organisms (streptococcus mutans, streptococcus sobrinus, lactobacilli and yeasts) in a large cohort of infants examined annually from 1 to 4 years of age. | 2001 | 11472804 |
| purification and characterization of an oligo-isomaltosaccharide synthase from a streptococcus sobrinus glucosyltransferase-i deficient mutant. | one glucosyltransferase (gtf) -i deficient mutant of streptococcus sobrinus strain b13n was isolated through chemical mutagenesis with ethyl methanesulfonate, and characterized. this mutant, designated as b13n-id, readily allowed us to purify a homogeneous oligo-isomaltosaccharide synthase (gtf-s) from its culture fluid. the purified gtf-s was only recognized with rabbit polyclonal antibody against recombinant gtf-s from an ecsherichia coli md124 clone expressing the b13n gtfs gene, and showed t ... | 2001 | 11471726 |
| a novel approach for purification of recombinant proteins using the dextran-binding domain. | using the dextran-binding domain (dbd) of a type of glucosyltransferase (gtf) from streptococcus sobrinus, we have developed a novel method for purifying recombinant proteins. dbd-tagged green and red fluorescent proteins as well as the parent gtf and dbd moiety were adsorbed well to commercially available cross-linked dextran (such as sephadex beads and sephacryl beads), and eluted efficiently with water-soluble dextran. the purity of the eluted proteins after this one-step affinity purificatio ... | 2001 | 11445073 |
| inhibitory effects of moabs against a surface protein antigen in real-time adherence in vitro and recolonization in vivo of streptococcus mutans. | a surface protein antigen (pac) of streptococcus mutans, particularly the a-region of the molecule, has been reported to interact with salivary components on the tooth surface. it might be a candidate antigen inducing the production of antibodies against the adherence of s. mutans to the tooth surface. we investigated the effects of monoclonal antibodies (moabs) obtained by immunization of synthetic pac peptides that completely correspond to the amino acid sequence of part of the a-region. these ... | 2001 | 11439156 |
| sealing ability of furcation perforation repair. | 1998 | 11431824 | |
| peroxidase reaction as a parameter for discrimination of streptococcus mutans and streptococcus sobrinus. | 425 strains of mutans streptococci and 12 reference strains were investigated by membrane fatty acid spectra (mfas) and peroxidase reaction (pr) after aerobic and anaerobic incubation. 423 strains were identified as streptococcus mutans. the remaining 2 strains were identified as streptococcus sobrinus. the pr of 29 strains was doubtful; immediately after anaerobic incubation a negative pr changed into a slightly positive pr. to test the diagnostic value of pr the strains were additionally inves ... | 2001 | 11423721 |
| dextran acceptor reaction of streptococcus sobrinus glucosyltransferase gtf-i as revealed by using uniformly 13c-labeled sucrose. | a sucrose glucosyltransferase gtf-i from cariogenic streptococcus sobrinus transferred the uniformly 13c-labeled glucosyl residue ([u-(13)c]glc) from [u-(13)c]sucrose to exogenous dextran t500 at the non-reducing-end, mostly by alpha-(1-->6) linkages and partially by alpha-(1-->3) linkages, as revealed by the 13c-(13)c nmr coupling pattern. with increasing amounts of [u-(13)c]sucrose, transfer of [u-(13)c]glc to the alpha-(1-->3)-linked chain became predominant without increase in the number of ... | 2001 | 11423107 |
| diepitopic construct of functionally and epitopically complementary peptides enhances immunogenicity, reactivity with glucosyltransferase, and protection from dental caries. | coimmunization with peptide constructs from catalytic (cat) and glucan-binding (glu) domains of glucosyltransferase (gtf) of mutans streptococci has resulted in enhanced levels of antibody to the cat construct and to gtf. we designed and synthesized a diepitopic construct (cat-glu) containing two copies of both cat (b epitope only) and glu (b and t epitope) peptides. the immunogenicity of this diepitopic construct was compared with that of individual cat and glu constructs by immunizing groups o ... | 2001 | 11401956 |
| growth rate and biofilm thickness of streptococcus sobrinus and streptococcus mutans on hydroxapatite. | bacteria in biofilm and planktonic bacteria exhibit different properties. the objective of the present study was to compare the growth rates of streptococcus sobrinus and streptococcus mutans on different types of biofilm with their planktonic growth rate. our experimental model consisted of hydroxyapatite beads coated with human saliva (sha). glucans or fructans were synthesized in situ on sha by immobilized cell-free glucosyltransferase or fructosyltransferase isolated from oral bacteria. s. s ... | 2001 | 11398997 |
| detection of streptococcal glucan-binding proteins in biofilms. | 2001 | 11398450 | |
| aspiration pneumonia: dental and oral risk factors in an older veteran population. | to investigate the importance of medical and dental factors in aspiration pneumonia in an older veteran population. | 2001 | 11380747 |
| analysis of bacterial detachment from substratum surfaces by the passage of air-liquid interfaces. | a theoretical analysis of the detachment of bacteria adhering to substratum surfaces upon the passage of an air-liquid interface is given, together with experimental results for bacterial detachment in the absence and presence of a conditioning film on different substratum surfaces. bacteria (streptococcus sobrinus hg1025, streptococcus oralis j22, actinomyces naeslundii t14v-j1, bacteroides fragilis 793e, and pseudomonas aeruginosa 974k) were first allowed to adhere to hydrophilic glass and hyd ... | 2001 | 11375160 |
| high-sucrose diet reduces defensive reactions of the pulpo-dentinal complex to dentinal caries in young rats. | the significance of systemic dietary effects on the response of the pulpo-dentinal complex to dentinal caries was examined. weanling rats were divided into high sucrose or control diet groups both with and without cariogenic bacterial inoculation. at the onset, tetracycline was injected to mark the dentin formation during the experiment. after 5-6 week, mandibular molars were sectioned sagittally. the areas of dentin formed during the experiment and those of dentinal caries were quantified separ ... | 2001 | 11370755 |
| membranotropic effects of the antibacterial agent triclosan. | triclosan is a broad-spectrum hydrophobic antibacterial agent used in dermatological preparations and oral hygiene products. to gain further insight into the mode of action of triclosan we examined its effects on membranes by performing leakage titrations of different oral bacteria and studying its interaction with model membranes through the use of different biophysical techniques. there was negligible efflux of intracellular material from streptococcus sobrinus at the minimal inhibitory concen ... | 2001 | 11368524 |
| antimicrobial activity of silver nitrate against periodontal pathogens. | metal ions were evaluated as potential antimicrobial agents suitable for local delivery in the oral cavity for the treatment of periodontitis. silver nitrate, copper chloride, and zinc chloride were tested for antimicrobial activity in in vitro killing assays conducted in phosphate buffered saline with a series of oral bacteria including gram-negative periodontal pathogens and gram-positive streptococci. copper and zinc salts failed to exhibit strong and consistent activity against periodontal p ... | 2001 | 11327077 |
| acidogenicity and acidurance of fluoride-resistant streptococcus sobrinus in vitro. | to induce fluoride-resistant mutants of streptococcus sobrinus in vitro and to study the acidogenic and acid tolerance of fluoride-resistant strains. | 2000 | 11314523 |
| effects of three different infant dentifrices on biofilms and oral microorganisms. | the purpose of this work was to evaluate the effects of infant dentifrices: a--with lactoperoxidase, glucose oxidase and lactoferrin; b--with 1100 ppm of naf and sodium lauryl sulfate; c--with extract of calendula. the dentifrices were test on biofilms formed in vitro from saliva and dental plaque of infants, using reference strains a. viscosus (atcc 43146); c. albicans (atcc 51501); l. casei (atcc 4646); s. mitis (atcc 49456); s. mutans (atcc 25175); s. oralis (atcc 35037); s. sanguis (atcc 105 ... | 2000 | 11314149 |
| antibacterial properties of dentin bonding systems, polyacid-modified composite resins and composite resins. | this study examined the antibacterial activities of the bonding systems syntac, ebs and scotchbond 1, the polyacid-modified composite resins hytac and compoglass, and the composite resins tetric, z100 and scalp-it. they were evaluated using the cariogenic bacteria streptococcus mutans, lactobacillus salivarius, streptococcus sorbinus and actinomyces viscosus in vitro with a modified cylinder drop plate agar diffusion assay. all adhesives of the dentin bonding systems and the polyacid-modified co ... | 2001 | 11298264 |
| comparison of erythritol and xylitol saliva stimulants in the control of dental plaque and mutans streptococci. | the effect of 2-month usage of saliva-stimulating pastils containing either erythritol or xylitol was studied in a cohort of 30 subjects assigned to the respective polyol groups (n = 15). the daily consumption level of both polyols was 5.2 g, used in 5 daily chewing episodes. the mean weight of total plaque mass (collectable during a standard period of 3 min from all available tooth surfaces) was reduced significantly in the xylitol-group, while no such effect was observed in the erythritol-grou ... | 2001 | 11275673 |
| validation of an in vitro biofilm model of supragingival plaque. | the study of biofilm structure and function mandates the use of model systems for which a host of environmental variables can be rigorously controlled. we describe a model of supragingival plaque containing actinomyces naeslundii, veillonella dispar, fusobacterium nucleatum, streptococcus sobrinus, and streptococcus oralis wherein cells are cultivated anaerobically in a saliva-based medium on hydroxyapatite discs coated with a salivary pellicle, with material and pieces of apparatus common to al ... | 2001 | 11269730 |
| cloning and dna sequencing of the surface protein antigen i/ii (paa) of streptococcus cricetus. | we have cloned and sequenced the gene encoding the surface protein antigen paa (antigen i/ii family) from streptococcus cricetus e49 (serotype a) using degenerate pcr. the deduced amino acid sequence of paa reveals two repeating regions (a region; alanine-rich region, p region; proline-rich region). two additional tandem repeats were found in the a region and part of the p region was deleted compared to antigen i/ii. homology and phylogenetic analyses reveal that paa is homologous to streptococc ... | 2001 | 11267788 |
| inhibition of bacterial and glucan adherence to various light-cured fluoride-releasing restorative materials. | this study investigated the potential plaque adhesion properties of various light-cured fluoride-releasing restorative materials by measuring the amount of adhering radiolabeled bacteria and glucan. | 2001 | 11239586 |
| spatial arrangements and associative behavior of species in an in vitro oral biofilm model. | the spatial arrangements and associative behavior of actinomyces naeslundii, veillonella dispar, fusobacterium nucleatum, streptococcus sobrinus, and streptococcus oralis strains in an in vitro model of supragingival plaque were determined. using species-specific fluorescence-labeled antibodies in conjunction with confocal laser scanning microscopy, the volumes and distribution of the five strains were assessed during biofilm formation. the volume-derived cell numbers of each strain correlated w ... | 2001 | 11229930 |
| dental caries is a preventable infectious disease. | dental caries is the most common infectious disease affecting humans. the principal causative agents are a group of streptococcal species collectively referred to as the mutans streptococci of which streptococcus mutans and streptococcus sobrinus are the most important agents of human caries. this review outlines what is currently known about these ubiquitous pathogens and discusses novel methods for elimination of these bacteria from dental plaque. | 2000 | 11225524 |
| adsorption of oral bacteria to porous type calcium carbonate. | the purpose of this study was to investigate the adsorption of [3h]-thymidine labeled oral microorganisms to porous type calcium carbonate (pcc) beads in a buffer containing human parotid saliva and to pcc combined chewing gum sheets. adsorption rates of streptococcus sobrinus b13 and 6715, streptococcus mutans mt8148r and actinomyces naeslundii t14v with pcc were significantly higher than those with calcium carbonate (cc) beads (p < 0.01). adsorption rates of s. sobrinus, s. mutans and a. naesl ... | 2000 | 11212584 |
| [effects of sodium doecyl sulfate on the artificial dental plaque in chemostat]. | sodium doecyl sulfate (sds) is widely used as a detergent in dentifrices. it has been shown to interfere with the protein adsorption to hydroxyapatite (ha), and inhibit acquired pellicle formation. the aim of the present study was to examine the effects of sds on the artificial dental plaque in chemostat. the amount of the 3h-labelled bacteria adhered on the enamel fragment surface was determined with scintillometer. the artificial dental plaque was observed under the scanning electron microscop ... | 1997 | 11189307 |
| the role of fructans on dental biofilm formation by streptococcus sobrinus, streptococcus mutans, streptococcus gordonii and actinomyces viscosus. | dental plaque biofilm plays a pivotal role in the progression of dental diseases. polysaccharides are of great importance in the ecology of the dental biofilm. we studied the effect of fructans, glucans and a mixture of both fructans and glucans, synthesized in situ by immobilized fructosyltransferase or glucosyltransferase, on the adhesion of streptococcus sobrinus, streptococcus mutans, streptococcus gordonii and actinomyces viscosus to hydroxyapatite beads coated with human saliva (sha). the ... | 2001 | 11179653 |
| hla-dr4 and salivary immunoglobulin a reactions to oral streptococci. | the aim of this study was to describe and compare salivary immunoglobulin a (iga) antibody reactions to extracts of strains of three oral streptococci in human leukocyte antigen (hla)-dr4-positive and -dr4-negative subjects. whole paraffin-stimulated saliva samples were collected from 27 apparently healthy subjects. previous hla typing showed that 20 subjects were dr4 positive and 7 were dr4 negative. hla-drb1*04 subtyping was performed among the dr4-positive subjects. whole-cell antigen extract ... | 2001 | 11169139 |
| differentiation of streptococcus mutans and streptococcus sobrinus via genotypic and phenotypic profiles from three different populations. | routine identification of streptococcus mutans and streptococcus sobrinus is generally based upon growth on various selective media, colony morphology and biochemical characteristics. we examined various approaches of differentiating these two species through a combination of the conventional phenotypic methodology with chromosomal dna fingerprint (cdf) and arbitrarily primed polymerase chain reaction (ap-pcr) methods. initially, ten atcc type strains and 20 randomly selected clinical isolates o ... | 2001 | 11169134 |
| induction of secretory immunity with bioadhesive poly (d,l-lactide-co-glycolide) microparticles containing streptococcus sobrinus glucosyltransferase. | the effect of mucosal delivery of streptococcus sobrinus glucosyltransferase (gtf) in bioadhesive poly (d,l-lactide-co-glycolide) (plga) microparticles on induction of salivary iga and serum igg antibody responses was measured in sprague-dawley rats. preparations of gtf/plga/gelatin microparticles, or plga/gelatin microparticles or gtf in alum, were administered four times at weekly intervals by intranasal or intragastric routes. two subcutaneous injections of gtf in plga/gelatin microparticles ... | 2000 | 11155176 |
| simple and rapid detection of streptococcus mutans and streptococcus sobrinus in human saliva by polymerase chain reaction. | streptococcus mutans and streptococcus sobrinus are major pathogens causing dental caries in humans. a simple and rapid method to detect these species in human saliva simultaneously was developed using the polymerase chain reaction (pcr). chromosomal dna was extracted by boiling bacterial cells in lysis solution containing 1% triton x-100. oligonucleotide primers specific for portions of the glucosyltransferase genes (gtfb of s. mutans and gtfi of s. sobrinus) were designed. after pcr using two ... | 2000 | 11154412 |
| xylitol-induced elevated expression of the gbpc gene in a population of streptococcus mutans cells. | xylitol possesses a unique property distinct from the other caries-preventive sweeteners. this sugar alcohol cannot be metabolized to acids but is taken up by streptococcus mutans and accumulated as a toxic sugar-phosphate in the cells, resulting in growth inhibition. due to the accumulation, xylitol induces biological responses including the emergence of xylitol-insensitive populations. therefore, we expected another response induced by xylitol and found a new phenomenon, that cells repeatedly ... | 2000 | 11153929 |
| the galu gene of streptococcus pneumoniae that codes for a udp-glucose pyrophosphorylase is highly polymorphic and suitable for molecular typing and phylogenetic studies. | the enzyme utp-glucose-1-phosphate uridylyltransferase (udp-glucose pyrophosphorylase, udpg:pp) is synthesized by practically all organisms, although prokaryotic udpg:pps are evolutionarily unrelated to the eukaryotic counterparts. the primary structure of prokaryotic udpg:pps is well conserved, although little information exists on the polymorphism of the genes coding for these enzymes. it has been reported that the galu gene encoding the streptococcus pneumoniae udpg:pp is absolutely required ... | 2000 | 11137293 |
| pcr for detection and identification of streptococcus sobrinus. | oligonucleotide primers were designed based upon a comparison of the dextranase gene (dex) sequences from streptococcus sobrinus and s. mutans. the primers amplified a 1610-bp long dna fragment on the dex gene by a pcr. the pair of primers was specific to s. sobrinus as the other members of the mutans streptococci - s. mutans, s. downei, s. cricetus, s. rattus, s. macacae and s. ferus - gave no pcr products. other gram-positive oral bacteria (15 strains of 10 species of cocci and 18 strains of 1 ... | 2000 | 11129717 |
| polycarboxylates inhibit the glucan-binding lectin of streptococcus sobrinus. | polycarboxylates, such as carboxymethylcellulose and hyaluronan, were found to be reversible inhibitors of the glucan-binding lectin of streptococcus sobrinus. when the carboxylate groups were coupled to ethylenediamine, or reduced with carbodiimide-borohydride, inhibitory powers were lost. similarly, n-deacetylated hyaluronan had poor inhibitory powers, probably due to the introduction of positive charges into the polymer. other polymers, such as chondroitin sulfates, dextran sulfate, fetuin, h ... | 2000 | 11099864 |
| antimicrobial effect of a novel ozone- generating device on micro-organisms associated with primary root carious lesions in vitro. | the aims of this present study were (1) to assess the antimicrobial effect of ozone from a novel ozone-generating device (heolozone, usa) [0.052% (v/v) in air delivered at a rate of 13.33 ml.s(-1)] on primary root carious lesions (prcls) and (2) to evaluate the efficacy of ozone specifically on streptococcus mutans and streptococcus sobrinus. in study 1, 40 soft prcls from freshly extracted teeth were randomly divided into two groups to test the antimicrobial effect on prcls from exposure to ozo ... | 2000 | 11093025 |
| strain-related acid production by oral streptococci. | acid production, in particular at low ph, is thought to be an important ecological determinant in dental caries. the aim of the present study was to determine the acid producing capability at different ph levels of 47 streptococcal strains, representing 9 species, isolated from human dental plaque. the bacteria were grown until mid log-phase under anaerobic conditions and acid production was measured in a ph-stat system at ph 7.0, 6.0, 5.5 and 5.0. at all ph values, the mean velocity of acid pro ... | 2000 | 11093023 |
| similarity of bacteriocin activity profiles of mutans streptococci within the family when the children acquire the strains after the age of 5. | it has been shown that there is a window of infectivity for mutans streptococci between the ages of 19 and 31 months, when many children acquire mutans streptococci transmitted from their mothers. part of the children that escape this window acquire mutans streptococci at a later age. in this group, maternal transmission is expected to be less prevalent. the present study compared the bacteriocin activity profiles of mutans streptococci isolated from mothers, fathers and children when the childr ... | 2000 | 11093022 |
| site-specific oral colonization of mutans streptococci detected by arbitrarily primed pcr fingerprinting. | the clonal diversity and colonization pattern of mutans streptococci within an individual were studied by using a total of 50 tooth site samples obtained from seven 3- to 7-year-old children. five children contributed saliva samples. from the 7 subjects, 90, 74, 81, 53, 83, 103, and 114 isolates (a total of 598) representing streptococcus mutans and streptococcus sobrinus were included for arbitrarily primed polymerase chain reaction (ap-pcr) fingerprinting. the children harbored one to four dif ... | 2000 | 11093021 |
| inhibitory effects of apple polyphenols and related compounds on cariogenic factors of mutans streptococci. | the inhibitory effects of apple polyphenols (app) on the synthesis of water-insoluble glucans by glucosyltransferases (gtf) of streptococci of the mutans group and on the sucrose-dependent adherence of the bacterial cells were examined in vitro. app markedly inhibited the activity of gtf purified from the cariogenic bacterial cells. however, app showed no significant effect on the growth of the cariogenic bacteria. the strongest gtf inhibitors in app were apple condensed tannins (act), a mixture ... | 2000 | 11087536 |
| low-cariogenicity of trehalose as a substrate. | the effects of trehalose on cariogenesis by mutans streptococci were investigated. | 2000 | 11082525 |
| automated immunofluorescence for enumeration of selected taxa in supragingival dental plaque. | the present study investigated a recently developed automated image analysis technique for its applicability to the enumeration of selected bacteria in supragingival dental plaque. following initial calibration, the system is capable to count fluorescence-labeled target cells in up to 48 samples without user interference. test samples contained a characteristic mixture of planktonic bacteria, small almost planar bacterial aggregates, and large, virtually indisruptable clumps with cells from mult ... | 2000 | 11037755 |
| differences in acidogenicity of s. sobrinus and s. rattus are linked to the catalytic efficiency of the glycolytic key enzyme phosphofructokinase. | this contribution describes the biochemical properties of two catalytically different phosphofructokinases (pfks) purified from streptococcus rattus lb 2 (pfk-rat) and streptococcus sobrinus omz 65 (pfk-sob), respectively. steady-state kinetics revealed k(m) = 0. 8 mm for pfk-rat and k(m) = 0.08 mm for pfk-sob for f-6-p as the substrate. the enzymes also differ in their ph profiles: whereas the highest activity of pfk-rat was measured at ph = 8.0, the optimum ph of pfk-sob was at ph = 7.0. in ad ... | 2000 | 11014908 |
| inhibitory effects of plant polyphenoloxidase on colonization factors of streptococcus sobrinus 6715. | exogenously added polyphenoloxidase (ec 1.14.18.1), an enzyme which oxidizes tyrosine residues and is commonly found in many dietary components, abolished the aggregation of streptococcus sobrinus 6715 by high-molecular-weight dextran. the enzyme decreased glucan-binding lectin and/or glucosyltransferase i activities. | 2000 | 10952624 |
| shifts in membrane fatty acid profiles associated with acid adaptation of streptococcus mutans. | cells of streptococcus mutans ua159 physiologically adapted to acidification during growth at ph 5 in glucose-limited chemostat cultures were enriched in mono-unsaturated and longer chain fatty acids compared with unadapted cells grown under the same conditions but at ph 7. ratios of unsaturated to saturated fatty acids in the cells were, respectively, 1.2 and 0.3. cyclopropane fatty acids were not detected. streptococcus sobrinus 6715, which is known to have minimal acid-adaptive capacity, show ... | 2000 | 10913871 |
| [effect of subinhibitory concentrations of various antimicrobials on insoluble glucan production, polystyrene adherence and bacterial surface hydrophobicity of streptococcus sobrinus]. | the effect of subinhibitory concentrations (1/2, 1/4, 1/8 of the mic) of amoxicillin, teicoplanin, clindamycin and erythromycin on the factors influencing the adherence and pathogenicity of streptococcus sobrinus was evaluated. these factors included insoluble glucan, polystyrene adherence and bacterial surface hydrophobicity. insoluble glucan was detected using a spectrophotometric method; polystyrene adherence was assessed using microtiter plates; and surface hydrophobicity was determined usin ... | 1999 | 10878518 |
| nigerooligosaccharide acceptor reaction of streptococcus sobrinus glucosyltransferase gtf-i. | nigerose and nigerooligosaccharides served as acceptors for a glucosyltransferase gtf-i from cariogenic streptococcus sobrinus to give a series of homologous acceptor products. the soluble oligosaccharides (dp 5-9) strongly activated the acceptor reaction, resulting in the accumulation of water-insoluble (1-->3)-alpha-d-glucan. the enzyme transferred the labeled glucosyl residue from d-[u-13c]sucrose to the 3-hydroxyl group at the non-reducing end of the (1-->3)-alpha-d-oligosaccharides, as uneq ... | 2000 | 10877092 |
| cariostatic activity of cacao mass extract. | chocolate is suspected to contain some caries-inhibitory substances. the cariostatic activity of cacao mass extract (cm), the main component of chocolate, was examined in vitro and in experimental animals. cm showed no detectable effects on the cellular growth and acid production of mutans streptococci. on the other hand, the cell-surface hydrophobicity of mutans streptococci was significantly reduced by the presence of cm. furthermore, insoluble glucan synthesis by the glucosyltransferases from ... | 2000 | 10869494 |
| caries inhibitory activity of cacao bean husk extract in in-vitro and animal experiments. | cacao bean husk extract (cbh) was examined for inhibitory effects on the caries-inducing properties of mutans streptococci in vitro and on caries development in specific pathogen-free sprague-dawley rats infected with mutans streptococci. cbh reduced the growth rate of almost all oral streptococci examined, which resulted in the reduction of acid production. furthermore, insoluble glucan synthesis by the glucosyltransferases from streptococcus mutans mt8148r and streptococcus sobrinus 6715 was s ... | 2000 | 10869475 |
| studies concerning the glucosyltransferase of streptococcus sanguis. | we have shown in previous studies that the glucosyltransferase (gtf) enzymes of streptococcus mutans have distinct properties when adsorbed to a surface. in the present study, we compared the activity of gtf from streptococcus sanguis, designated gtfss, in solution and on the surface of saliva-coated hydroxyapatite (sha) beads, and determined the ability of its product glucan to support the adherence of oral microorganisms. gtf from s. sanguis 804 nctc 10904 was purified from culture supernatant ... | 2000 | 10867431 |
| the anticariogenic effect of amine fluorides on streptococcus sobrinus and glucosyltransferase in biofilms. | dental caries is a chronic infectious disease caused by the accumulation of bacterial plaque (biofilm) on tooth surfaces. antibacterial agents, in addition to other preventive measures, can control dental plaque accumulation. amine fluorides (amf) are known anticaries agents for over 30 years. the purpose of our study was to assess the adsorption and desorption of amf to experimental dental biofilm and to evaluate the effect of amf on streptococcus sobrinus 6715 and glucosyltransferase (gtf) act ... | 2000 | 10867426 |
| immunolabeling of the major cell surface protein antigen of streptococcus sobrinus with monoclonal antibody. | the purpose of this study was to determine the accessibility of monoclonal antibody (mcab), specific for the major cell surface protein antigen (pag) of streptococcus sobrinus, to the surface of its native epitopes. | 1999 | 10863403 |
| effect of surface roughness of porcelain on adhesion of bacteria and their synthesizing glucans. | in some instances of porcelain restoration, refinishing is inevitable. in terms of plaque accumulation on porcelain, refinishing could be a substitute method for glazing. | 2000 | 10842136 |
| fluoride release and antibacterial properties of new-generation tooth-colored restoratives. | the aim of this study was to compare the amounts and pattern of fluoride release and antibacterial properties of new-generation restoratives over a 35-day period. materials evaluated included fluoride-releasing composites (tetric, experimental x), compomers (dyract, compoglass), and a resin-modified glass-ionomer cement (fuji ii lc). a conventional glass ionomer (fuji ii cap) was used as a control for fluoride-release testing. five samples of each restorative material were evaluated for daily fl ... | 1999 | 10823077 |
| in vitro antibacterial effect of rc-prep components on streptococcus sobrinus. | the aim of this study was to examine the bacteriostatic and bactericidal effects of the components of rc-prep: edta, urea peroxide and glycol. the minimal inhibitory concentration and the minimal bactericidic concentration of edta, urea peroxide and glycol were tested on the viability of streptococcus sobrinus (s. sobrinus). the combined antibacterial effect of these components was also examined on s. sobrinus. the minimal inhibitory concentration of edta was found to be 0.125%, of urea peroxide ... | 1999 | 10815566 |
| effects of resin composite components on glucosyltransferase of cariogenic bacterium. | the aim of our study was to investigate the effect of resin composite components on glucan synthesis by glucosyltransferase (gtase) derived from a cariogenic bacterium, streptococcus sobrinus b13. the eluates from cured composites stored in 0.05 mol/l potassium phosphate buffer (kpb) (ph 6.8) for 2 weeks at 37 degrees c stimulated the formation of water-insoluble glucan, whereas those from amalgam inhibited it. this finding suggests that the eluates from the resin composites enhance gtase activi ... | 2000 | 10813753 |
| caries-associated micro-organisms in infants from different socio-economic backgrounds in scotland. | the aims of this study were: (1) to compare the frequency of isolation of mutans streptococci, (streptococcus mutans, steptococcus sobrinus), lactobacilli and yeasts (caries-associated micro-organisms) in the saliva of 1-year-old infants with and without dental caries; and (2) to determine if socio-economic background influenced the frequency isolation of bacteria and caries status. | 2000 | 10785295 |
| modulation of glucan-binding protein activity in streptococci by fluoride. | glucan-binding lectin (gbl) activity of streptococcus sobrinus was significantly reduced by fluoride in the growth medium. approximately 1.5 mm fluoride was required for a 50% reduction in gbl activity. in addition to the gbl, several other glucan-binding proteins were reduced when the bacteria were grown in subinhibitory fluoride. fluoride had no effect on glucosyltransferases (gtfs), enzymes capable of converting sucrose into alpha-1,6-glucans. all the proteins were detected by use of enhanced ... | 2000 | 10779686 |
| current understanding of the cause of dental caries. | dental caries-associated oral streptococci are called the mutans streptococci, with streptococcus mutans and streptococcus sobrinus being the most prevalent caries-associated organisms in humans. strains of the mutans streptococci are highly conserved within not only mothers and their children but also racial groups, suggesting vertical transmission of this organism within human populations. it has been found that the mother-child infection route of the mutans streptococci can be prevented by si ... | 2000 | 10777849 |