Publications
Title | Abstract | Year Filter | PMID(sorted descending) Filter |
---|
shigellosis studies; resistance of shigella flexneri iii to therapy with sulfadiazine. | 1946 | 21022905 | |
active immunization of children with shigella vaccines. | 1945 | 21021615 | |
the phase variation of shigella paradysenteriae (flexner) type iv. | 1946 | 21018824 | |
shigella paradysenteriae (flexner) type ii. vii. | 1946 | 21018819 | |
a comparison of rabbit and mouse antisera to shigella paradysenteriae. | 1946 | 21018814 | |
the mannitol-negative shigella group. | 1946 | 21018707 | |
the antigenic complex of shigella paradysenteriae, boyd type p274. | 1946 | 21018687 | |
observations concerning the growth of three species of shigella on bismuth sulfite agar. | 1946 | 21018339 | |
the detoxification by acetylation of soluble antigens from shigella dysenteriae (shiga) and e. typhosa. | 1946 | 21017963 | |
shigella types from eastern france. | 1946 | 21016044 | |
two paracolon cultures related antigenically to shigella paradysenteriae. | 1946 | 21014237 | |
a thermolabile substance of shigella dysenteriae shiga. | 1946 | 21013070 | |
studies with the somatic antigen of shigella para-dysenteriae (flexner). | 1946 | 21012783 | |
occurrence of shigella types in the military population of the southeastern united states, 1943 and 1944. | 1946 | 21009284 | |
the importance of paracolon organisms with salmonella and shigella antigens. | 1945 | 21007049 | |
distribution of shigella in india as determined by spot agglutination with absorbed sera. | 1945 | 21006721 | |
shigella equirulis infection in california. | 1945 | 21005490 | |
a study of shigella by means of bacteriophage. | 1945 | 21005127 | |
typing sera for the genus shigella. | 1945 | 21004173 | |
relationship between precipitative and protective anti-bodies of type iii shigella paradysenteriae (flexner) immune serum. | 1945 | 21004030 | |
the antigenicity of shigella paradysenteriae (flexner) in saline-in-mineral-oil emulsion. | 1945 | 21004019 | |
the type-specificity of immune protection against shigella paradysenteriae (flexner). | 1945 | 21003545 | |
antigens of shigella sonnei. | 1945 | 21003541 | |
preparation and evaluation of an irradiated toxoid from the toxin of shigella dysenteriae. | 1946 | 21001448 | |
the increase of bacteriophage in vivo during experimental infections with shigella paradysenteriae flexner in mice. | 1946 | 20996528 | |
two new types of shigella flexneri. | 1946 | 20996438 | |
hydrogen sulfide formation by shigella alkalescens. | 1946 | 20994881 | |
the increased antigenicity of shigella paradysenteriae (flexner) in saline-in-mineral-oil emulsion; experiments in mice and rabbits. | 1946 | 20992665 | |
bacteriology of a collection of shigella strains typed by weil's method. | 1946 | 20988553 | |
shigella sp. wakefield and its relations to shigella sp. sachs q454. | 1946 | 20988491 | |
immunochemical studies on the shigella paradysenteriae (flexner). | 1946 | 20987082 | |
relationships of proshigella dispar to other proshigella and shigella species. | 1946 | 20987018 | |
an additional shigella paradysenteriae serotype. | 1946 | 20985564 | |
the detoxification by acetylation of soluble antigens from shigella dysenteriae and e. typhosa. | 1946 | 20984596 | |
shigellosis studies; clinical observations on dysentery caused by shigella flexneri iii. | 1946 | 20982721 | |
[susceptibility surveillance of clinical isolates to fluoroquinolone antimicrobial agents from 2003 to 2008: post-marketing study of prulifloxacin]. | yearly changes in the susceptibility of clinical isolates to ulifloxacin (ufx) and other fluoroquinolones were examined through surveys over 3 periods. in the first survey, 534 strains derived from 19 species were collected from clinical specimens during 6 months from december 2003 to may 2004. in the same way, 805 strains were collected from december 2005 to may 2006 in the second survey, and 863 strains were from december 2007 to may 2008 in the third survey. over these 3 study periods, the su ... | 2010 | 20976880 |
atypical class 1 integron coexists with class 1 and class 2 integrons in multi-drug resistant shigella flexneri isolates from china. | the antimicrobial resistance and the character of integrons were determined in 58 shigella flexneri strains isolated from china. all isolates were multi-drug resistant and found to carry integrons of class 1 (94.8%), class 2 (100%), or both (94.8%). no inti3 was detected. the typical class 1 integrons were found in conjugative plasmids and could be transferred to the recipient e. coli dh5α. the gene cassettes of typical class 1 integrons dfra17-aada5 and dfra12-orff-aada2 were detected in 54 str ... | 2010 | 20976456 |
ikkα contributes to canonical nf-κb activation downstream of nod1-mediated peptidoglycan recognition. | during pathogen infection, innate immunity is initiated via the recognition of microbial products by pattern recognition receptors and the subsequent activation of transcription factors that upregulate proinflammatory genes. by controlling the expression of cytokines, chemokines, anti-bacterial peptides and adhesion molecules, the transcription factor nuclear factor-kappa b (nf-κb) has a central function in this process. in a typical model of nf-κb activation, the recognition of pathogen associa ... | 2010 | 20976174 |
prominent human health impacts from several marine microbes: history, ecology, and public health implications. | this paper overviews several examples of important public health impacts by marine microbes and directs readers to the extensive literature germane to these maladies. these examples include three types of dinoflagellates (gambierdiscus spp., karenia brevis, and alexandrium fundyense), bmaa-producing cyanobacteria, and infectious microbes. the dinoflagellates are responsible for ciguatera fish poisoning, neurotoxic shellfish poisoning, and paralytic shellfish poisoning, respectively, that have pl ... | 2010 | 20976073 |
enhancement of reactive oxygen species production and chlamydial infection by the mitochondrial nod-like family member nlrx1. | chlamydia trachomatis infections cause severe and irreversible damage that can lead to infertility and blindness in both males and females. following infection of epithelial cells, chlamydia induces production of reactive oxygen species (ros). unconventionally, chlamydiae use ros to their advantage by activating caspase-1, which contributes to chlamydial growth. nlrx1, a member of the nod-like receptor family that translocates to the mitochondria, can augment ros production from the mitochondria ... | 2010 | 20959452 |
health effects of the 1991 bangladesh cyclone: report of a unicef evaluation team. | to assess the impact on health of the cyclone and tidal wave that struck the southern coast of bangladesh on the evening of 29 april 1991, a team of health professionals visited cyclone affected areas from 4-27 june, 1991. team members met with health workers and officials of the government of bangladesh and with staff pom nongovernmental organizations, and conducted field surveys in two severely affected areas. mortality among the 135 households surveyed (pre-cyclone population 1,123) was 14 pe ... | 1993 | 20958764 |
subtype prevalence, plasmid profiles and growing fluoroquinolone resistance in shigella from kolkata, india (2001-2007): a hospital-based study. | shigellosis is a major public health problem, and increasing antimicrobial resistance has complicated its treatment. we report isolation frequency, plasmid profiles and antimicrobial resistance of shigella subtypes in kolkata, india, from a prospective hospital-based study. | 2010 | 20955371 |
surveillance of shigellosis by real-time pcr suggests underestimation of shigellosis prevalence by culture-based methods in a population of rural china. | shigellosis is a leading public health issue in china, especially in children under 5 years of age. the disease burden of shigellosis is usually underestimated by conventional culture. in this study, real-time pcr was applied to detect shigella infection in parallel with routine culture, to investigate the true burden of disease caused by shigella spp. | 2010 | 20951728 |
rapid multiple-locus variable-number tandem-repeats analysis of shigella spp. using multicolour capillary electrophoresis. | the multiple-locus variable-number tandem-repeats analysis (mlva) method for genotyping has proven to be a fast and reliable typing tool in several bacterial species. mlva is in our laboratory the routine typing method for salmonella enterica subsp. enterica serovar typhimurium, escherichia coli (two assays), listeria monocytogenes and yersinia enterocolitica. the gram-negative invasive enteropathogenic bacterium shigella is the most common cause of bacillary dysentery (shigellosis) worldwide, a ... | 2010 | 20951171 |
integron types, gene cassettes, antimicrobial resistance genes and plasmids of shigella sonnei isolates from outbreaks and sporadic cases in taiwan. | this study analysed the presence, location and transferability of integrons and antibiotic resistance genes in 103 shigella sonnei outbreak isolates and in 32 sporadic isolates from taiwan. multiple antimicrobial resistance was common in both outbreak (95 %) and sporadic (97 %) isolates. class 1 integrons were present in 34 outbreak isolates (33 %) and in six sporadic isolates (19 %). this study is the first, to our knowledge, to identify an atypical sul3-associated class 1 integron carrying the ... | 2010 | 20947666 |
an fda bioinformatics tool for microbial genomics research on molecular characterization of bacterial foodborne pathogens using microarrays. | advances in microbial genomics and bioinformatics are offering greater insights into the emergence and spread of foodborne pathogens in outbreak scenarios. the food and drug administration (fda) has developed a genomics tool, arraytrack™, which provides extensive functionalities to manage, analyze, and interpret genomic data for mammalian species. arraytrack™ has been widely adopted by the research community and used for pharmacogenomics data review in the fda's voluntary genomics data submissio ... | 2010 | 20946615 |
expression of bacterial virulence factors and cytokines during in vitro macrophage infection by enteroinvasive escherichia coli and shigella flexneri: a comparative study. | enteroinvasive escherichia coli (eiec) and shigella spp cause bacillary dysentery in humans by invading and multiplying within epithelial cells of the colonic mucosa. although eiec and shigella share many genetic and biochemical similarities, the illness caused by shigella is more severe. thus, genomic and structure-function molecular studies on the biological interactions of these invasive enterobacteria with eukaryotic cells have focused on shigella rather than eiec. here we comparatively stud ... | 2010 | 20944993 |
characterization and antimicrobial activity of 4-(β-d-glucopyranosyl-1→4-α-l-rhamnopyranosyloxy)-benzyl thiocarboxamide; a novel bioactive compound from moringa oleifera seed extract. | antimicrobial activity of crude seed extract of moringa oleifera was investigated by thin layer chromatography bioassay against escherichia coli, pseudomonas aeruginosa, staphylococcus aureus, cladosporium cladosporioides, and penicillium sclerotigenum; most of them were prominently inhibited by an isolate with r(f) 0.92-0.96. characterization and identification of the extract revealed the occurrence of three bioactive compounds: 4-(α-l-rhamnopyranosyloxy)benzyl isothiocyanate, methyl n-4-(α-l-r ... | 2010 | 20941575 |
combination of two separate binding domains defines stoichiometry between type iii secretion system chaperone ipgc and translocator protein ipab. | type iii secretion systems (ttsss) utilized by enteropathogenic bacteria require the presence of small, acidic virulence-associated chaperones for effective host cell infection. we adopted a combination of biochemical and cellular techniques to define the chaperone binding domains (cbds) in the translocators ipab and ipac associated with the chaperone ipgc from shigella flexneri. we identified a novel cbd in ipab and furthermore precisely mapped the boundaries of the cbds in both translocator pr ... | 2010 | 20937829 |
domains of the shigella flexneri type iii secretion system ipab protein involved in secretion regulation. | type iii secretion systems (t3sss) are key determinants of virulence in many gram-negative bacterial pathogens. upon cell contact, they inject effector proteins directly into eukaryotic cells through a needle protruding from the bacterial surface. host cell sensing occurs through a distal needle "tip complex," but how this occurs is not understood. the tip complex of quiescent needles is composed of ipad, which is topped by ipab. physical contact with host cells initiates secretion and leads to ... | 2010 | 20937761 |
shigella deploy multiple countermeasures against host innate immune responses. | although the intestinal epithelium is equipped with multiple defense systems that sense bacterial components, transmit alarms to the immune system, clear the bacteria, and renew the injured epithelial lining, mucosal bacterial pathogens are capable of efficiently colonizing the intestinal epithelium, because they have evolved systems that modulate the inflammatory and immune responses of the host and exploit the harmful environments as replicative niches. in this review we highlight current topi ... | 2010 | 20934372 |
viable but nonculturable state of foodborne pathogens in grapefruit juice: a study of laboratory. | several foodborne human pathogens, when exposed to harsh conditions, enter viable but nonculturable (vbnc) state; however, still open is the question whether vbnc pathogens could be a risk for public health, because, potentially, they can resuscitate. moreover, cultural methods for food safety control were not able to detect vbnc forms of foodborne bacteria. particularly, it has not been established whether food chemophysical characteristics can induce vbnc state in contaminating pathogen bacter ... | 2010 | 20932087 |
[screening of harmine tolerance/degrading bacteria from camel rumen]. | peganum harmala, a famous traditional chinese drug, contains a variety of alkaloids and toxic for many animals. camels mainly live in desert or semi-desert areas, with the robust gastrointestine system in digesting various feed including toxic plants without disease symptoms. | 2010 | 20931866 |
bacterial enteropathogens and risk factors associated with childhood diarrhea. | to investigate the etiology of bacterial enteropathogens causing diarrhea among children; to elucidate the risk factors, sign and symptoms involved in developing of infection; and to identify the antimicrobial susceptibility pattern. | 2010 | 20924718 |
selective testing of ß-galactosidase activity in the laboratory identification of salmonella and shigella species. | salmonella and shigella species are pathogens of great medical and public health importance. however, laboratory identification of these organisms is time consuming. using current standard laboratory algorithms, the vast majority of organisms submitted for serological typing with salmonella-specific and shigella-specific antisera are not clinically significant. | 2010 | 20924038 |
pediatric diarrhea in southern ghana: etiology and association with intestinal inflammation and malnutrition. | diarrhea is a major public health problem that affects the development of children. anthropometric data were collected from 274 children with (n = 170) and without (n = 104) diarrhea. stool specimens were analyzed by conventional culture, polymerase chain reaction for enteroaggregative escherichia coli (eaec), shigella, cryptosporidium, entamoeba, and giardia species, and by enzyme-linked immunosorbent assay for fecal lactoferrin levels. about 50% of the study population was mildly to severely m ... | 2010 | 20889896 |
improved fructosylated chondroitin production by kfoc overexpression in e. coli k4. | escherichia coli k4 is one of the bacteria expressing a surface polysaccharide, indicated as capsular polysaccharide (k-antigen), showing a chemical structure that resembles that of metabolites commonly used in pharmaceutical applications. in this study we provide evidence that homologous overexpression of the chondroitin polymerase, encoded by the kfoc gene, acts on a potential bottleneck for production of capsular polysaccharide, and increases productivity by 100%. however, we also demonstrate ... | 2010 | 20888875 |
defensins play a crucial role in protecting mice against oral shigella flexneri infection. | an earlier study revealed that 4-day-old mice, but not older mice, were infected with invasive shigella strains. here we attempted to determine the underlying mechanism that induces inflammation in the intestines of neonate mice after oral shigella infection. wild-type balb/c mice of different ages (7, 14, and 35 days old) were orally administered gfp-expressing shigella flexneri 5a m90t strain (5 x 10⁹ cfu) and analyzed for colonization 6h following infection. we found that shigella localized i ... | 2010 | 20888321 |
antidiarrheal activity of extracts and compound from trilepisium madagascariense stem bark. | the present study was performed to evaluate the preventive and curative antidiarrheal effects of the methanol extract, fractions and compound from the stem bark of trilepisium madagascariense in rats. | 2010 | 20871767 |
improved detection of five major gastrointestinal pathogens by use of a molecular screening approach. | the detection of bacterial and parasitic gastrointestinal pathogens through culture and microscopy is laborious and time-consuming. we evaluated a molecular screening approach (msa) for the detection of five major enteric pathogens: salmonella enterica, campylobacter jejuni, giardia lamblia, shiga toxin-producing escherichia coli (stec), and shigella spp./enteroinvasive e. coli (eiec), for use in the daily practice of a clinical microbiology laboratory. the msa consists of prescreening of stool ... | 2010 | 20861334 |
prevalence of bacteria and parasites in white ibis in egypt. | a field survey was conducted to evaluate the prevalence of bacterial infections among free-living white ibis (nipponia nippon) in which 92 bacterial isolates were recovered from 193 different internal organs of 55 apparently healthy ibis. escherichia coli and salmonella spp. were isolated at rates of 43.6% and 14.5%, respectively. the other bacterial pathogens isolated were shigella spp. (34.5%), enterobacter spp. (21.8%) citrobacter spp. (18.1%), klebsiella pneumonia (16.3), staphylococcus aure ... | 2010 | 20857378 |
infectious colitis. | purpose of review: the incidence of gastrointestinal infections continues to increase and infectious colitis contributes to significant morbidity and mortality worldwide. the purpose of this review is to highlight the recent advances in knowledge of pathogens causing infectious colitis. we describe the various pathogens and specifically focus on enterohemorrhagic escherichia coli (ehec) o157:h7, salmonella, shigella, campylobacter, and entamoeba histolytica infections, and their impact on long-t ... | 2010 | 20856114 |
predacious bacteria, bdellovibrio with potential for biocontrol. | bacteria of the genus of bdellovibrio are highly motile gram-negative predators of other gram-negative bacteria causing lysis of their prey. here we report results of studies on the interactions of bdellovibrio with species of alcaligenes, campylobacter, erwinia, escherichia, helicobacter, pseudomonas, legionella, and shigella in agar lower, liquid media and cells attached to a surface. helicobacter pylori was studied employing both actively growing and viable but nonculturable (vbnc) cells. the ... | 2010 | 20850380 |
dysbiosis of fecal microbiota in crohn's disease patients as revealed by a custom phylogenetic microarray. | a custom phylogenetic microarray composed of small subunit ribosomal rna probes, representing ≈500 bacterial species from the human and animal gut, was developed and evaluated for analysis of gut microbial diversity using fecal samples from healthy subjects and crohn's disease (cd) patients. | 2010 | 20848492 |
assessment of the microbiological safety of dried spices and herbs commercialized in spain. | spices and herbs are natural products or their blends that must be free of extraneous matter content. conventional production of these products implicates a number of hygienic problems so spices and herbs may be exposed to a wide range of microbial contamination during pre- and post-harvest and they can present high microbial counts. in this study, we have analyzed the microbial quality of 53 samples of spices and dry herbs collected from spanish markets detecting a contamination of samples of s ... | 2010 | 20848208 |
formulation and immunogenicity of a potential multivalent type iii secretion system-based protein vaccine. | the virulence of many pathogenic gram-negative bacteria is dependent upon their type iii secretion (tts) systems. here, we discuss initial formulation studies of five tts needle tip proteins ipad (shigella flexneri), bipd (burkholderia pseudomallei), sipd (salmonella spp.), lcrv (yersinia spp.), and pcrv (pseudomonas aeruginosa) as targets for subunit vaccines. excipient screening and subsequent assays lead to the selection of 10% sucrose and 5% dextrose as an optimal stabilizer combination for ... | 2010 | 20845449 |
formulation and immunogenicity studies of type iii secretion system needle antigens as vaccine candidates. | bacterial infections caused by shigella flexneri, salmonella typhimurium, and burkholderia pseudomallei are currently difficult to prevent due to the lack of a licensed vaccine. here we present formulation and immunogenicity studies for the three type iii secretion system (ttss) needle proteins mxih(δ5), prgi(δ5), and bsal(δ5) (each truncated by five residues at its c terminus) as potential candidates for vaccine development. these antigens are found to be thermally stabilized by the presence of ... | 2010 | 20845448 |
mass spectrometry biotyper system identifies enteric bacterial pathogens directly from colonies grown on selective stool culture media. | we evaluated the performance and cost-effectiveness of a matrix-assisted laser desorption ionization time-of-flight mass spectrometry-based biotyper system for the routine identification of common enteric bacterial pathogens seen in middle tennessee from suspicious colonies grown on selective stool culture media. a total of 304 suspicious colonies were selected and further identified from 605 stool specimens. the suspicious colonies were analyzed by the biotyper system, and the results were comp ... | 2010 | 20844226 |
normal aerobic bacterial conjunctival flora in the crab-eating raccoon (procyon cancrivorus) and coati (nasua nasua) housed in captivity in pernambuco and paraiba (northeast, brazil). | to determine the normal aerobic bacterial conjunctival population of the coatis and the crab-eating raccoons housed in captivity in the pernambuco and paraiba states of brazil. | 2010 | 20840103 |
transmembrane bax inhibitor motif containing (tmbim) family proteins perturbs a trans-golgi network enzyme, gb3 synthase, and reduces gb3 biosynthesis. | globotriaosylceramide (gb3) is a well known receptor for shiga toxin (stx), produced by enterohemorrhagic escherichia coli and shigella dysenteriae. the expression of gb3 also affects several diseases, including cancer metastasis and fabry disease, which prompted us to look for factors involved in its metabolism. in the present study, we isolated two cdnas that conferred resistance to stx-induced cell death in hela cells by expression cloning: ganglioside gm3 synthase and the cooh terminus regio ... | 2010 | 20837469 |
the effects of x-ray radiation on escherichia coli o157:h7, listeria monocytogenes, salmonella enterica and shigella flexneri inoculated on whole roma tomatoes. | in the last two decades several foodborne disease outbreaks associated with produce were reported. tomatoes, in particular, have been associated with several multi-state salmonella outbreaks. inactivation of inoculated escherichia coli o157:h7, listeria monocytogenes, salmonella enterica and shigella flexneri on whole roma tomato surfaces by x-ray at 0.1, 0.5, 0.75, 1.0, and 1.5 kgy was studied. the main purpose of this study was to achieve a 5 log reduction in consistent with the recommendation ... | 2010 | 20832685 |
a disulfide driven domain swap switches off the activity of shigella ipah9.8 e3 ligase. | we show that the monomeric form of shigella ipah9.8 e3 ligase catalyses the ubiquitination of human u2af35 in vitro, providing a molecular mechanism for the observed in vivo effect. we further discover that under non-reducing conditions ipah9.8 undergoes a domain swap driven by the formation of a disulfide bridge involving the catalytic cysteine and that this dimer is unable to catalyse the ubiquitination of u2af35. the crystal structure of the domain-swapped dimer is presented. the redox inacti ... | 2010 | 20831869 |
development of a multiplex real-time pcr assay with internal amplification control for the detection of shigella species and enteroinvasive escherichia coli. | shigella species, particularly s. sonnei and s. flexneri, remain some of the leading bacterial etiological agents of gastrointestinal diseases in the united states and globally. the isolation and detection of these foodborne pathogens are critical for preventing the spread of disease and facilitating epidemiological investigations aimed at determining the source of a shigella infection outbreak. a multiplex real-time pcr-based assay was developed that targets all four species of shigella plus en ... | 2010 | 20828467 |
molecular mechanisms of necroptosis: an ordered cellular explosion. | for a long time, apoptosis was considered the sole form of programmed cell death during development, homeostasis and disease, whereas necrosis was regarded as an unregulated and uncontrollable process. evidence now reveals that necrosis can also occur in a regulated manner. the initiation of programmed necrosis, 'necroptosis', by death receptors (such as tumour necrosis factor receptor 1) requires the kinase activity of receptor-interacting protein 1 (rip1; also known as ripk1) and rip3 (also kn ... | 2010 | 20823910 |
near-atomic resolution analysis of bipd, a component of the type iii secretion system of burkholderia pseudomallei. | burkholderia pseudomallei, the causative agent of melioidosis, possesses a type iii protein secretion apparatus that is similar to those found in salmonella and shigella. a major function of these secretion systems is to inject virulence-associated proteins into target cells of the host organism. the bipd gene of b. pseudomallei encodes a secreted virulence factor that is similar in sequence and is most likely to be functionally analogous to ipad from shigella and sipd from salmonella. proteins ... | 2010 | 20823511 |
effect of freeze-drying on viability and in vitro probiotic properties of a mixture of lactic acid bacteria and yeasts isolated from kefir. | the effect of freeze-drying on viability and probiotic properties of a microbial mixture containing selected bacterial and yeast strains isolated from kefir grains (lactobacillus kefir, lactobacillus plantarum, lactococcus lactis, saccharomyces cerevisiae and kluyveromyces marxianus) was studied. the microorganisms were selected according to their potentially probiotic properties in vitro already reported. two types of formulations were performed, a microbial mixture (mm) suspended in milk and a ... | 2011 | 20822567 |
comparison of chromogenic biolog rainbow agar shigella/aeromonas with xylose lysine desoxycholate agar for isolation and detection of shigella spp. from foods. | shigella outbreaks are widely reported throughout the world. however, it remains a challenge to isolate shigella spp. from foods by using conventional microbiological media. the main objective of this study was to determine the effectiveness of a novel chromogenic medium, rainbow agar shigella/aeromonas (rainbow agar), for the isolation and detection of shigella spp. in foods. all four shigella species, s. sonnei, s. flexneri, s. dysenteriae, and s. boydii, were studied. rainbow agar was compare ... | 2010 | 20819355 |
a disposable immunosensor for shigella flexneri based on multiwalled carbon nanotube/sodium alginate composite electrode. | a novel shigella flexneri immunosensor based on horseradish peroxidase-labeled antibodies to s. flexneri (hrp-anti-s. flexneri) immobilized by physical adsorption on the multiwalled carbon nanotube (mwcnt)/sodium alginate (sa) composite modified screen-printed electrode surface was successfully fabricated. in this strategy, mwcnt/sa biocomposite acted as the matrix to adsorb and immobilize hrp-anti-s. flexneri. the modified electrodes were characterized with an atomic force microscope and cyclic ... | 2011 | 20816661 |
prevalence and antimicrobial resistance of diarrheagenic escherichia coli and shigella species associated with acute diarrhea in tehran, iran. | a study was performed to determine the prevalence and antimicrobial resistance of shigella species and diarrheagenic escherichia coli isolates cultured from patients with acute diarrhea in tehran, iran. between may 2003 and may 2005, 1120 diarrheal specimens were collected and assayed for bacterial enteropathogens by conventional and molecular methods. etiological agents were isolated from 564 (50.3%) specimens, and included 305 (54%) e coli, 157 (27.8%) shigella species, and 102 (18%) from othe ... | 2009 | 20808457 |
an outbreak of shigellosis due to shigella flexneri serotype 3a in a prison in iran. | on june 16 and 17, 2007, the medical clinic of a prison in isfahan, iran received multiple reports of gastrointestinal illness among prisoners. a cross-sectional study was therefore undertaken to determine the extent, causative agent and possible source of the outbreak. | 2010 | 20804308 |
sensitization of microcin j25-resistant strains by a membrane-permeabilizing peptide. | microcin j25 (mccj25) is a plasmid-encoded, 21-amino-acid, antibacterial peptide produced by escherichia coli. mccj25 inhibits rna polymerase and the membrane respiratory chain. mccj25 uptake into e. coli-sensitive strains is mediated by the outer membrane receptor fhua and the inner membrane proteins tonb, exbb, exbd, and sbma. this peptide is active on some e. coli, salmonella, and shigella species strains, while other gram-negative bacteria, such as clinical isolates of enterobacter cloacae, ... | 2010 | 20802073 |
antidiarrheal activity, chemical and toxicity profile of berberis aristata. | context: this study evaluated the in vitro and in vivo antidiarrheal activity, oral acute toxicological profile, and developed a chemical fingerprint of berberis aristata linn. (berberidaceae). materials and methods: the ethanol (by maceration) and aqueous (by soxhlet) extracts of berberis aristata bark were used for the study. the study involved the antimicrobial (minimum inhibitory concentration (mic) and minimum bactericidal concentration (mbc) by micro dilution) and antidiarrheal (castor oil ... | 2011 | 20738174 |
plasmon-induced inactivation of enteric pathogenic microorganisms with ag-agi/al2o3 under visible-light irradiation. | the plasmon-induced photocatalytic inactivation of enteric pathogenic microorganisms in water using ag-agi/al(2)o(3) under visible-light irradiation was investigated. the catalyst was found to be highly effective at killing shigella dysenteriae (s. dysenteriae), escherichia coli (e. coli), and human rotavirus type 2 wa (hrv-wa). its bactericidal efficiency was significantly enhanced by hco(3)(-) and so(4)(2-) ions, which are common in water, while phosphate had a slightly positive effect on the ... | 2010 | 20734989 |
[the evolution of the etiological structure of shigellosis]. | 2010 | 20734730 | |
association of water-borne diseases morbidity pattern and water quality in parts of ibadan city, nigeria. | occurrence of diarrhoea and other water-borne diseases in cities of developing countries has been on the increase over the decades largely due to unsafe water, inadequate sanitation and poor hygiene among human population. this study examined the relationship between the spatial pattern of water-borne diseases vis-a-vis water quality in parts of ibadan city in nigeria. data on 1334 cases of various water-borne diseases was collected from eight public hospitals with catchments covering the study ... | 2009 | 20734698 |
pad4 is essential for antibacterial innate immunity mediated by neutrophil extracellular traps. | neutrophils trap and kill bacteria by forming highly decondensed chromatin structures, termed neutrophil extracellular traps (nets). we previously reported that histone hypercitrullination catalyzed by peptidylarginine deiminase 4 (pad4) correlates with chromatin decondensation during net formation. however, the role of pad4 in net-mediated bacterial trapping and killing has not been tested. here, we use pad4 knockout mice to show that pad4 is essential for net-mediated antibacterial function. u ... | 2010 | 20733033 |
[dysentery and amoebiasis in poland in 2008]. | the number as well as incidence rate of notified as shigellosis, bacillary dysentery cases in xxi century are every year lower. only 33 cases were notified in the year 2008 (incidence rate 0.09/100 000 population), while the 64 cases were notified in 2007 (incidence rate 0.17/100 000), but 35 (incidence rate 0.09) were notified in 2006 and median in the 2002-2006 years was 75 cases, incidence rate 0.2/100 000 population. since 2000 no one-death case was notified. several imported cases were noti ... | 2010 | 20731222 |
medicinal potions used against infectious bowel diseases in mayan traditional medicine. | since one of the main health problems of the indigenous population are infectious bowel diseases, we decided to test mayan medicinal potions used to treat these conditions against some of the causal agents. | 2010 | 20728517 |
lactoferrin increases both resistance to salmonella typhimurium infection and the production of antibodies in mice. | lactoferrin (lf) is a multifunctional iron-binding glycoprotein with antibacterial and immunomodulatory activities. the antibacterial influence of orally administered bovine lf (blf) against murine infection caused by salmonella typhimurium (s. typhimurium) has scarcely been explored. in the current study, balb/c mice were treated orally for 7 days with either 5 or 100mg of bovine lactoferrin (blf). on day 7 of treatment, mice were intragastrically infected with a lethal or sublethal dose of col ... | 2010 | 20727369 |
serum neopterin is elevated in patients infected with shigella. | abstract: | 2010 | 20727206 |
uncivil engineers: chlamydia, salmonella and shigella alter cytoskeleton architecture to invade epithelial cells. | the obligate intracellular bacterial pathogen chlamydia trachomatis is a major cause of blindness and sexually transmitted diseases. like the enteric pathogens salmonella and shigella, chlamydia injects effector proteins into epithelial cells to initiate extensive remodeling of the actin cytoskeleton at the bacterial attachment site, which culminates in the engulfment of the bacterium by plasma membrane extensions. numerous salmonella and shigella effectors promote this remodeling by activating ... | 2010 | 20722600 |
detection of airborne bacteria in a german turkey house by cultivation-based and molecular methods. | today's large-scale poultry production with densely stocked and enclosed production buildings is often accompanied by very high concentrations of airborne microorganisms leading to a clear health hazard for employees working in such environments. depending on the expected exposure to microorganisms, work has to be performed under occupational safety conditions. in this study, turkey houses bioaerosols were investigated by cultivation-based and molecular methods in parallel to determine the conce ... | 2010 | 20720091 |
development of a pcr protocol for the detection of escherichia coli o157:h7 and salmonella spp. in surface water. | escherichia coli o157:h7 and salmonella are pathogenic microorganisms that can cause severe gastrointestinal illness in humans. these pathogens may be transmitted in a variety of ways, including food and water. the presence of salmonella and e. coli o157:h7 in surface waters constitutes a potential threat to human health when used for either drinking or recreation. as with most waterborne pathogens, salmonella and e. coli o157:h7 are difficult to detect and enumerate with accuracy in surface wat ... | 2011 | 20714926 |
csra and cra influence shigella flexneri pathogenesis. | shigella flexneri is a facultative intracellular pathogen that invades and disrupts the colonic epithelium. in order to thrive in the host, s. flexneri must adapt to environmental conditions in the gut and within the eukaryotic cytosol, including variability in the available carbon sources and other nutrients. we examined the roles of the carbon consumption regulators csra and cra in a cell culture model of s. flexneri virulence. csra is an activator of glycolysis and a repressor of gluconeogene ... | 2010 | 20713625 |
seasonal variation of enteropathogens in infants and preschoolers with acute diarrhea in western mexico. | the present study estimates the prevalence of some enteropathogens in infants and preschoolers with acute diarrhea. from 2006 to 2007, 5459 consecutive stool samples were evaluated. cryptosporidium parvum was the parasite identified with the higher frequency (5.1%), followed by giardia lamblia (1.2%). campylobacter jejuni was isolated in 858 cases (15.7%) and was the most frequent enteropathogen overall. the rates of c parvum, shigella, and salmonella were higher in the summer. rotavirus had the ... | 2010 | 20706147 |
foodborne proportion of gastrointestinal illness: estimates from a canadian expert elicitation survey. | the study used a structured expert elicitation survey to derive estimates of the foodborne attributable proportion for nine illnesses caused by enteric pathogens in canada. it was based on a similar study conducted in the united states and focused on campylobacter, escherichia coli o157:h7, listeria monocytogenes, nontyphoidal salmonella enterica, shigella spp., vibrio spp., yersinia enterocolitica, cryptosporidium parvum, and norwalk-like virus. for each pathogen, experts were asked to provide ... | 2010 | 20704505 |
comparative in vitro activity of tigecycline and other antimicrobial agents against shigella species from kuwait and the united arab of emirates. | shigella species isolated from stool samples of symptomatic patients of all age groups at the mubarak al kabir hospital and infectious diseases hospital, kuwait and tawam hospital, uae during a 2-year period were investigated for their susceptibility to tigecycline and several other antibiotics by determining the minimum inhibitory concentrations (mics) using the e test method. a total of 100 and 42 strains were collected from uae and kuwait, respectively. the extent of drug resistance in the sh ... | 2010 | 20701889 |
production of glycoprotein vaccines in escherichia coli. | conjugate vaccines in which polysaccharide antigens are covalently linked to carrier proteins belong to the most effective and safest vaccines against bacterial pathogens. state-of-the art production of conjugate vaccines using chemical methods is a laborious, multi-step process. in vivo enzymatic coupling using the general glycosylation pathway of campylobacter jejuni in recombinant escherichia coli has been suggested as a simpler method for producing conjugate vaccines. in this study we descri ... | 2010 | 20701771 |
[mucocutaneous abnormalities in chlamydia trachomatis-induced reactive arthritis]. | reactive arthritis (previously known as reiters syndrome) is an inflammatory arthritis that is a type of spondyloarthropathy. the disease consists of the classical triad of arthritis, urethritis and conjunctivitis, but mucocutaneous abnormalities also frequently appear: balanitis circinata, keratoderma blennorrhagicum, aphthous ulcers in the mouth and nail disorders. these skin lesions are mainly found in reactive arthritis induced by chlamydia trachomatis (ct). reactive arthritis is often trigg ... | 2010 | 20699017 |
diverse pathways for salicin utilization in shigella sonnei and escherichia coli carrying an impaired bgl operon. | utilization of the aryl-β-glucosides salicin or arbutin in most wild-type strains of e. coli is achieved by a single-step mutational activation of the bgl operon. shigella sonnei, a branch of the diverse e. coli strain tree, requires two sequential mutational steps for achieving salicin utilization as the bglb gene, encoding the phospho-β-glucosidase b, harbors an inactivating insertion. we show that in a natural isolate of s. sonnei, transcriptional activation of the gene sso1595, encoding a ph ... | 2010 | 20697693 |