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the informatics for diabetes and education telemedicine (ideatel) project.telemedicine is a promising but largely unproven technology for providing case management services to patients with chronic conditions who experience barriers to access to care or a high burden of illness. we conducted a randomized controlled trial comparing telemedicine case management to usual care, with blinding of those obtaining outcome data, in 1,665 medicare recipients with diabetes, aged 55 years or greater, and living in federally designated medically underserved areas of new york state ...200718528511
sensitivity and specificity of a single emergency department measurement of urinary neutrophil gelatinase-associated lipocalin for diagnosing acute kidney injury.a single serum creatinine measurement cannot distinguish acute kidney injury from chronic kidney disease or prerenal azotemia.200818519927
project viva: a multilevel community-based intervention to increase influenza vaccination rates among hard-to-reach populations in new york city.we sought to determine whether the work of a community-based participatory research partnership increased interest in influenza vaccination among hard-to-reach individuals in urban settings.200818511725
knowledge and misconceptions regarding upper respiratory infections and influenza among urban hispanic households: need for targeted messaging.to characterize knowledge and misconceptions regarding viral upper respiratory infections (uri) among urban hispanics and identify correlates of greater knowledge.200918506622
epidemiologic research on man-made disasters: strategies and implications of cohort definition for world trade center worker and volunteer surveillance program.studies of long-term health consequences of disasters face unique methodologic challenges. the authors focused on studies of the health of cleanup and recovery workers, who are often poorly enumerated at the outset and difficult to follow over time. comparison of the experience at the world trade center disaster with 4 past incidents of chemical and radiation releases at seveso, italy; bhopal, india; chernobyl, ukraine; and three mile island, usa, provided useful contrasts. each event had method ...200818500709
wtc medical monitoring and treatment program: comprehensive health care response in aftermath of disaster.the attack on the world trade center (wtc) on september 11th, 2001 exposed thousands of individuals to an unprecedented mix of chemicals, combustion products and micronized building materials. clinicians at the mount sinai irving selikoff center for occupational and environmental medicine, in partnership with affected stakeholder organizations, developed a medical screening program to evaluate the health status of workers and volunteers who spent time at the wtc site and thus sustained exposure ...200818500708
standardization of spirometry in assessment of responders following man-made disasters: world trade center worker and volunteer medical screening program.spirometry is the most commonly used pulmonary function test to screen individuals for suspected lung disease. it is also used for screening workers with exposures to agents associated with pulmonary diseases. although the american thoracic society (ats) provides guidelines for spirometers and spirometry techniques, many factors are not standardized, so that results from individual pulmonary function laboratories vary substantially. these differences can create substantial difficulties in using ...200818500705
effects of behavioral intervention on substance use among people living with hiv: the healthy living project randomized controlled study.reductions in substance use were examined in response to an intensive intervention with people living with human immunodeficiency virus (hiv) (plh).200818494840
effect of timing of amantadine chemoprophylaxis on severity of outbreaks of influenza a in adult long-term care facilities.long-term care facilities (ltcfs) are vulnerable to outbreaks of influenza. there are limited data on the impact of antiviral chemoprophylaxis on the duration of outbreaks of influenza. we investigated the association of timely initiation of amantadine chemoprophylaxis on the duration and severity of outbreaks of influenza a in ltcfs in new york, new york.200818484879
summary of the development of a signature for detection of residual dust from collapse of the world trade center buildings.the collapse of the world trade center (wtc) towers on september 11, 2001, caused lower manhattan and adjacent areas to be covered in millimeters to centimeters of dust. wtc dust penetrated into indoor spaces, and public health concerns remain regarding exposure to possible residual dust in the affected areas. the goal of the studies outlined in this review was to determine which, if any, components of the bulk wtc dust are sufficiently above typical background dust levels in new york city to de ...200918478046
dna hypermethylation and clinicopathological features in breast cancer: the western new york exposures and breast cancer (web) study.aberrant dna hypermethylation of gene promoter regions has been increasingly recognized as a common molecular alteration in carcinogenesis. we evaluated the association between major clinicopathological features and hypermethylation of genes in tumors among 803 incidence breast cancer cases from a large population-based case-control study conducted in western new york state. dna samples were isolated from archive paraffin embedded tumor tissue and were analyzed for hypermethylation status of the ...200918463976
availability of trivalent inactivated influenza vaccine to parents of neonatal intensive care unit patients and its effect on the healthcare worker vaccination rate.trivalent inactivated influenza vaccine (tiv) is indicated for healthcare workers (hcws); however, the vaccination rate in this population is estimated at 35%. we implemented a program for the administration of tiv, targeted at parents of neonatal intensive care unit (nicu) patients.200818462142
[the establishment of psychiatric genetics in germany, great britain and the usa, ca. 1910-1960. to the inseparable history of eugenics and human genetics].the article reconstructs the emergence of institutionalized research programs in the field of psychiatric genetics. it focuses on the first institutions in this field in germany, the united kingdom, and the united states: the genealogisch-demographische abteilung (gda) at the deutsche forschungsanstalt für psychiatrie in munich founded in 1917/18; the program (later: department) of medical genetics at the new york state psychiatric institute, associated with columbia university, and founded in 1 ...200718447192
a new addition to the mosquito fauna of the suny oneonta biological field station, otsego county, new york.an apparent natural introduction and establishment of a population of anopheles walkeri into an ecological research site is documented. likelihood of introduction by human activity is discussed.200818437821
primary vaccine failure after 1 dose of varicella vaccine in healthy children.universal immunization of young children with 1 dose of varicella vaccine was recommended in the united states in 1995, and it has significantly decreased the incidence of chickenpox. outbreaks of varicella, however, are reported among vaccinated children. although vaccine effectiveness has usually been 85%, rates as low as 44% have been observed. whether this is from primary or secondary vaccine failure-or both-is unclear. we tested serum samples from 148 healthy children immunized against vari ...200818419532
the genomic and epidemiological dynamics of human influenza a virus.the evolutionary interaction between influenza a virus and the human immune system, manifest as 'antigenic drift' of the viral haemagglutinin, is one of the best described patterns in molecular evolution. however, little is known about the genome-scale evolutionary dynamics of this pathogen. similarly, how genomic processes relate to global influenza epidemiology, in which the a/h3n2 and a/h1n1 subtypes co-circulate, is poorly understood. here through an analysis of 1,302 complete viral genomes ...200818418375
seroprevalence of herpes simplex virus type 2 and characteristics associated with undiagnosed infection: new york city, 2004.herpes simplex virus type 2 (hsv-2) infection is associated with substantial morbidity and increased risk for human immunodeficiency virus acquisition. we describe hsv-2 seroprevalence in adult new yorkers, and examine the relationship between select characteristics, infection, and diagnosis.200818418295
polymorphisms in rad51, xrcc2, and xrcc3 are not related to breast cancer risk. 200818398049
voices from the battlefield: reports of the daily experiences of urban black mothers.there are persistent disparities in maternal child health in the united states. in this study i used an ethnographic design to portray the everyday lives of 130 black, low-income, urban mothers. the women described daily battles related to a lack of material and human resources. to deal with these challenges, they assumed the role of soldiers, developed new tactical maneuvers, trusted in god for justice, shared their resources with their comrades, took short-lived breaks when they were wounded i ...200818350419
greater drug injecting risk for hiv, hbv, and hcv infection in a city where syringe exchange and pharmacy syringe distribution are illegal.comparing drug-injecting risk between cities that differ in the legality of sterile syringe distribution for injection drug use provides a natural experiment to assess the efficacy of legalizing sterile syringe distribution as a structural intervention to prevent human immunodeficiency virus (hiv) and other parenterally transmitted infections among injection drug users (idus). this study compares the parenteral risk for hiv and hepatitis b (hbv) and c (hcv) infection among idus in newark, nj, us ...200818340537
markers for hepatitis a, b and c in methadone maintained patients: an unexpectedly high co-infection with silent hepatitis b.to determine the prevalence of hepatitis a, b and c viruses in patients attending a methadone maintenance clinic in new york city.200818339114
gender of pediatric recombinant human growth hormone recipients in the united states and globally.gender disparities were found in reports of early pediatric recombinant human gh (rhgh) use in the united states. with rhgh entering its third decade, we sought to examine u.s. gender-based treatment patterns and how these patterns compare with that of other countries.200818334582
us civilian smallpox preparedness and response program, 2003.variola virus, the cause of smallpox disease, has been deemed a possible bioterrorism agent. since november 2001, federal, state, and local public health partners implemented activities to prepare for a possible smallpox outbreak. the centers for disease control and prevention (cdc) produced and delivered training and educational materials for smallpox preparedness in many formats, developed detailed smallpox vaccine information statements about vaccine contraindications and vaccination site car ...200818284355
breastfeeding and infant illness in low-income, minority women: a prospective cohort study of the dose-response relationship.the authors' objective was to determine whether cumulative weekly breastfeeding duration by 13 weeks was associated with infant otitis media, respiratory and gastrointestinal illness, and total illness visits up to 12 months. the authors performed a secondary analysis of data from a randomized clinical trial of low-income, primarily hispanic and black women enrolled from 2 medical center affiliated clinics. "breastfeeding sensitive" (bfs) outpatient and emergency room (er) visit data for the abo ...200818281352
evaluation of pathways for release of rift valley fever virus into domestic ruminant livestock, ruminant wildlife, and human populations in the continental united states.to evaluate the feasibility for rift valley fever virus (rvfv) to enter the continental united states by various routes as well as to identify states in which domestic and wild ruminant and human populations would be most vulnerable to exposure to rvfv.200818279085
factors associated with the prevalence and incidence of trichomonas vaginalis infection among african american women in new york city who use drugs.trichomoniasis vaginalis, the most prevalent nonviral sexually transmitted infection, is associated with negative reproductive outcomes and increased hiv transmission and may be overrepresented among african americans.200818275272
assessment of interactions between pah exposure and genetic polymorphisms on pah-dna adducts in african american, dominican, and caucasian mothers and newborns.polycyclic aromatic hydrocarbons (pah) are widespread pollutants commonly found in air, food, and drinking water. benzo[a]pyrene is a well-studied representative pah found in air from fossil fuel combustion and a transplacental carcinogen experimentally. pahs bind covalently to dna to form dna adducts, an indicator of dna damage, and an informative biomarker of potential cancer risk. associations between pah-dna adduct levels and both cancer risk and developmental deficits have been seen in prev ...200818268125
influenza-testing and antiviral-agent prescribing practices--connecticut, minnesota, new mexico, and new york, 2006-07 influenza season.influenza is a major cause of morbidity and mortality in the united states, with an average of 36,000 deaths attributed to the disease annually. patients with influenza-like illness (ili) often are evaluated by their primary-care physicians (pcps). antiviral therapy initiated within 48 hours of ili symptom onset can shorten the course of influenza illness; antiviral therapy also is used as chemoprophylaxis for influenza, particularly in institutions and communities. early laboratory diagnosis an ...200818219266
genetic relationships of jamestown canyon virus strains infecting mosquitoes collected in connecticut.jamestown canyon virus (jcv) (family bunyaviridae, genus orthobunyavirus) is maintained in a mosquito-deer cycle and has been implicated in the etiology of meningitis and encephalitis with human cases reported from ontario, canada, michigan, connecticut, and new york. despite the recognition of symptomatic cases in the northeastern united states, little is known about the genetic relationships of jcv variants circulating in this region. accordingly, we compared the phylogenetic relationships of ...200718165540
richard selzer: premiere american surgeon-writer.richard selzer (b.1928) is one of the most prominent american surgeon-authors alive today. only sherwin nuland (b.1930), from yale university medical school as selzer was, carries the same outstanding virtues of good surgery and excellent writing. recently, atul gawande (b. 1965) has taken a road similar to these two distinguished predecessors. selzer has produced 14 books of superb scholarship and immense value for the active and committed surgeon. he describes, with unusual grace and wit, diff ...200718097871
population prevalence of reported and unreported hiv and related behaviors among the household adult population in new york city, 2004.surveillance for hiv likely underestimates infection among the general population: 25% of us residents are estimated to be unaware of their hiv infection.200818097231
trivalent inactivated influenza vaccine compliance rate in neonatal intensive care unit parents.the american academy of pediatrics (aap) recommends injected, inactivated influenza vaccine for all close contacts of high-risk infants. this population includes parents of infants younger than 59 months of age, with an emphasis on children 0-6 months who are not direct candidates for immunization. this 0-6 month age group is a major component of the neonatal intensive care unit (nicu) population. no data exist on the compliance rate with influenza vaccine in this specific parent population. the ...200718097211
nicu lactation consultant increases percentage of outborn versus inborn babies receiving human milk.to determine the effect of a dedicated lactation consultant (lc) on the percentage of neonates receiving any human milk in the neonatal intensive care unit (nicu) and at discharge over time.200818094704
does the effect of pm10 on mortality depend on pm nickel and vanadium content? a reanalysis of the nmmaps data.lack of knowledge regarding particulate matter (pm) characteristics associated with toxicity is a crucial research gap. short-term effects of pm can vary by location, possibly reflecting regional differences in mixtures. a report by lippmann et al. [lippmann et al., environ health perspect 114:1662-1669 (2006)] analyzed mortality effect estimates from the national morbidity, mortality, and air pollution study (nmmaps) for 1987-1994. they found that average concentrations of nickel or vanadium in ...200718087586
making the connections: community capacity for tobacco control in an urban african american community.developing community capacity to improve health is a cornerstone of community-based public health. the concept of community capacity reflects numerous facets and dimensions of community life and can have different meanings in different contexts. this paper explores how members of one community identify and interpret key aspects of their community's capacity to limit the availability and use of tobacco products. particular attention is given to examining the interrelationship between various dime ...200818080743
assessment of inhalation exposures and potential health risks to the general population that resulted from the collapse of the world trade center towers.in the days following the collapse of the world trade center (wtc) towers on september 11, 2001 (9/11), the u.s. environmental protection agency (epa) initiated numerous air monitoring activities to better understand the ongoing impact of emissions from that disaster. using these data, epa conducted an inhalation exposure and human health risk assessment to the general population. this assessment does not address exposures and potential impacts that could have occurred to rescue workers, firefig ...200718076491
comments on the nonpharmaceutical interventions in new york city and chicago during the 1918 flu pandemic.this commentary was originally published in cidrap news and it is here reported almost verbatim to allow divulgation through open access. the editorial summarizes john barry's concerns about the value of accurate historical reporting and its implications in public policy determination. this short abstract was written by the editor-in-chief of the journal of translational medicine to introduce the editorial.200718072975
the role of vitamin d3 in preventing infections. 200818056725
herpes simplex virus-2 and hiv among noninjecting drug users in new york city.to examine the relationship between herpes simplex virus 2 (hsv-2) seroprevalence and human immunodeficiency virus (hiv) seroprevalence among noninjecting heroin and cocaine users in new york city.200718049425
tetrabromobisphenol a (tbbpa) and hexabromocyclododecanes (hbcds) in tissues of humans, dolphins, and sharks from the united states.concentrations of tetrabromobisphenol a (tbbpa) and alpha-, beta-, and gamma-isomers of hexabromocyclododecanes (hbcds) were determined by liquid chromatography-tandem mass spectrometry (lc-esi-ms/ms) in human adipose tissue obtained in new york city, and in three marine top-level predators--bottlenose dolphin, bull shark, and atlantic sharpnose shark--collected from coastal waters of florida, usa. the overall mean concentrations (mean+/-sd) of tbbpa and hbcds were 0.048+/-0.102 and 0.333+/-0.57 ...200818037156
nonpharmaceutical interventions implemented during the 1918-1919 influenza pandemic. 200718029825
conspicuous impacts of inconspicuous hosts on the lyme disease epidemic.emerging zoonotic pathogens are a constant threat to human health throughout the world. control strategies to protect public health regularly fail, due in part to the tendency to focus on a single host species assumed to be the primary reservoir for a pathogen. here, we present evidence that a diverse set of species can play an important role in determining disease risk to humans using lyme disease as a model. host-targeted public health strategies to control the lyme disease epidemic in north a ...200818029304
population vulnerabilities and capacities related to health: a test of a model.variability in the health of human populations is greater in economically vulnerable areas. we tested whether this variability reflects and can be explained by: (1) underlying vulnerabilities and capacities of populations and/or (2) differences in the distribution of individual socioeconomic status between populations. health outcomes were rates of mortality from 12 causes (cardiovascular disease, malignant neoplasms, accidents, chronic lower respiratory disease, cerebrovascular disease, pneumon ...200818022302
human subjects protection in a study of caregivers of community-residing persons with dementia.this article describes the processes and methods used to protect human subjects during a joint research project undertaken by a state health department and a university-based research team. the use of a statewide registry to obtain a sample of primary caregivers of persons with dementia provided a unique opportunity for the research team to interview a large and representative sample of caregivers. at the same time, it raised complex issues regarding the privacy of the primary caregivers and the ...200018019958
acute respiratory disease associated with adenovirus serotype 14--four states, 2006-2007.adenovirus serotype 14 (ad14) is a rarely reported but emerging serotype of adenovirus that can cause severe and sometimes fatal respiratory illness in patients of all ages, including healthy young adults. in may 2006, an infant in new york aged 12 days died from respiratory illness caused by ad14. during march-june 2007, a total of 140 additional cases of confirmed ad14 respiratory illness were identified in clusters of patients in oregon, washington, and texas. fifty-three (38%) of these patie ...200718004235
traumatic arteriovenous fistula due to an old gunshot injury: a victim from the afghanistan war.a 75-year-old man referred to the outpatient vascular surgery clinic of taleghani hospital (shaheed beheshti university of medicine, tehran, iran) due to a local nontender mass in his groin. in his history, it was discovered that the mass had appeared a few months after a gunshot injury. he had a history of shortness of breath with a new york heart association functional class fluctuating between ii and iii, but no history of smoking or addiction. in the physical examination, a 5-cm by 5-cm nonp ...200717985781
depleted uranium contamination by inhalation exposure and its detection after approximately 20 years: implications for human health assessment.inhaled depleted uranium (du) aerosols are recognised as a distinct human health hazard and du has been suggested to be responsible in part for illness in both military and civilian populations that may have been exposed. this study aimed to develop and use a testing procedure capable of detecting an individual's historic milligram-quantity aerosol exposure to du up to 20 years after the event. this method was applied to individuals associated with or living proximal to a du munitions plant in c ...200817976690
genetic polymorphisms in the apoptosis-associated genes fas and fasl and breast cancer risk.fas and fas ligand (fasl) play key roles in apoptotic signaling and down-regulation of this pathway may facilitate tumorigenesis. alterations in apoptosis genes may affect cancer risk by influencing individual susceptibility to environmental carcinogens. using a population-based breast cancer case-control study on long island, new york, we examined whether polymorphisms in fas and fasl modified the association between breast cancer risk and a marker of environmental exposures, polycyclic aromati ...200717962219
phylogenetic analysis reveals the global migration of seasonal influenza a viruses.the winter seasonality of influenza a virus in temperate climates is one of the most widely recognized, yet least understood, epidemiological patterns in infectious disease. central to understanding what drives the seasonal emergence of this important human pathogen is determining what becomes of the virus during the non-epidemic summer months. herein, we take a step towards elucidating the seasonal emergence of influenza virus by determining the evolutionary relationship between populations of ...200717941707
polymorphisms in nucleotide excision repair genes, polycyclic aromatic hydrocarbon-dna adducts, and breast cancer risk.genes involved in the nucleotide excision repair (ner) pathway, which removes bulky dna adducts, are potential low-penetrance cancer susceptibility genes. we recently reported an association between detectable polycyclic aromatic hydrocarbon (pah)-dna adducts and breast cancer risk. using a population-based breast cancer case-control study on long island, new york, we examined whether polymorphisms in ner genes modified the association between pah-dna adducts and breast cancer risk. we examined ...200717932351
comparative fetal mortality in maternal virus diseases. a prospective study on rubella, measles, mumps, chicken pox and hepatitis.comparative data on fetal and neonatal deaths following maternal mumps, rubella, hepatitis, chicken pox and measles were obtained in a prospective study in new york city from 1957 to 1964, inclusive. the evidence pointed to an increase in early fetal death rate after rubella and mumps and an increase in perinatal mortality after rubella and hepatitis. a significant increase in these rates was not demonstrable for chicken pox and measles in the selected population studied and under the conditions ...196617926883
enterocytozoon bieneusi in mature dairy cattle on farms in the eastern united states.fecal specimens were obtained from mature milking cows on farms in vermont, new york, pennsylvania, maryland, virginia, north carolina, and florida. polymerase chain reaction (pcr)-positive specimens for enterocytozoon bieneusi were found in 24 of 541 cows examined (4.4%) and on 12 of 14 farms. the prevalence of e. bieneusi varied considerably from farm to farm, with the lowest prevalence (2.3%) on fl-2 and the highest prevalence (12.5%) on vt-2. none of the cows exhibited signs of diarrhea. all ...200717899197
prevalence and risk factors for clinically significant drug interactions with antiretroviral therapy.to identify the prevalence and types of clinically significant drug interactions (csdis) in the drug regimens of patients with human immunodeficiency virus (hiv) infection who were receiving antiretroviral therapy, and to explore risk factors for these csdis.200717896893
distributions of pharmaceuticals in an urban estuary during both dry- and wet-weather conditions.pharmaceuticals and selected major human metabolites are ubiquitous in jamaica bay, a wastewater-impacted estuary at concentrations in the low ng/l to low/microg/l range. concentrations throughout the bay are often consistent with conservative behavior during dry-weather conditions, as evidenced by nearly linear concentration-salinity relationships. deviation from conservative behavior is noted for some pharmaceuticals and attributed to microbial degradation. caffeine, cotinine, nicotine, and pa ...200717874789
predictors of homelessness among older adults in new york city: disability, economic, human and social capital and stressful events.we interviewed 61 housed and 79 homeless adults aged 55 and over about disability; economic, human and social capital; and stressful life events prior to becoming homeless. over half of the homeless group had previously led conventional lives. human capital, social capital and life events were more important than disability or economic capital in predicting homelessness. the homeless adults were younger, more likely to be male and better educated than housed adults, but had shorter job tenure an ...200717855456
the role of home in hiv/aids: a visual approach to understanding human-environment interactions in the context of long-term illness.to better understand the human-environment experience, particularly within the context of chronic illness, eight hiv-positive participants provided a guided tour of the interior and exterior spaces of their residence. a video camera recorded all visual and verbal elements of the tours so that the interviewer could more accurately represent each individual's story of illness as it pertained to his or her home. four primary roles of the home were identified which include self-expression, control, ...200817855152
integrating multiple programme and policy approaches to hepatitis c prevention and care for injection drug users: a comprehensive approach.new york state is home to an estimated 230,000 individuals chronically infected with hepatitis c virus (hcv) and roughly 171,500 active injection drug users (idus). hcv/hiv co-infection is common and models of service delivery that effectively meet idus' needs are required. a hcv strategic plan has stressed integration.200717854731
how can hepatitis c be prevented in the long term?significant advances have been made in preventing hiv infection among injectors but we still know little about preventing hepatitis c (hcv). both prevalence and incidence of hepatitis c can remain high among idus even in the context of widespread implementation of harm reduction programmes. we need to develop new ways to fill the knowledge gap regarding hcv prevention. one way is to learn from the experts--those idus who, after long-term injection in social milieus of high hepatitis c prevalence ...200717854720
the effects of multifocal refractive lenses on occipital extension and forward head posture during a visual task.the purpose of this study was to determine if a change in forward head posture and occipital extension occurred in participants who wore multifocal lenses vs. those persons with non-multifocal lenses while performing an 8-min visual reading task on a visual display unit (vdu). forty-two healthy human participants were recruited for this study. thirty-three participants completed the study. fourteen participants wore multifocal lenses and 19 wore frames with non-multifocal lenses. to evaluate the ...200717852377
human papillomavirus seroprevalence among young male and female drug users.to determine seroprevalence and correlates of exposure to hpv 16, 18, and 53 among 15- to 30-year-old drug users in baltimore, md.200717847165
nutrient intakes in women and risks of anophthalmia and microphthalmia in their offspring.there is a paucity of information about risk factors for the human eye anomalies anophthalmia and microphthalmia. in this population-based case-control study we investigated whether periconceptional intakes of supplemental folic acid, dietary folate, vitamin a, and several other nutrients were associated with these eye defects.200717847120
giancarlo rastelli: the scientist, the man.doctor giancarlo rastelli graduated from the university of parma, italy (cum laude) in july 1957, and in 1961, moved to the mayo clinic, rochester, new york. the name of dr. rastelli is recognized worldwide for the classification of the atrioventricular (av) canal and for the procedure relating to the anatomical repair of transposition of the great arteries (tga) with ventricular septal defect (vsd) and pulmonary stenosis (ps). the most extraordinary aspect of his successful research work was th ...200717803207
administration of inactivated trivalent influenza vaccine to parents of high-risk infants in the neonatal intensive care unit.infants who are younger than 6 months and have influenza demonstrate significant morbidity and mortality. trivalent inactivated influenza vaccine is indicated for parents and household contacts of these infants; however, the influenza vaccination rate in this population is estimated at 30%. the objective of this study was to determine the feasibility of trivalent inactivated influenza vaccine administration to parents in a tertiary-care, level iii nicu and measure the effect of this program on v ...200717766502
relative prevalence of different sexually transmitted infections in hiv-discordant sexual partnerships: data from a risk network study in a high-risk new york neighbourhood.to determine infection patterns of sexually transmitted infections that facilitate hiv transmission among hiv-discordant couples.200817728340
viewpoint: developing a research ethics consultation service to foster responsive and responsible clinical research.although clinical ethics has become a central, and welcome, component of the health care landscape, research ethics consultation services are still uncommon. indeed, the usual approach to ethical concerns in research with human subjects has been primarily a regulatory one. nonetheless, ethical problems also arise in the context of research and thus collaborations between investigators and research ethicists are as essential as those between physicians and clinical ethicists. the authors argue th ...200717726404
voluntary rapid human immunodeficiency virus (hiv) testing in jails.to provide human immunodeficiency virus (hiv) rapid testing to persons in jails, identify previously undiagnosed cases of hiv infection, and refer hiv-infected inmates to care, treatment, and prevention services.200917724428
violations of human rights: health practitioners as witnesses.for humanitarian health-care practitioners bearing witness to violations of human dignity has become synonymous with denunciations, human rights advocacy, or lobbying for political change. a strict reliance on legal interpretations of humanitarianism and human rights is inadequate for fully understanding the problems inherent in political change. with examples from the hiv/aids epidemic in the usa, the rwandan genocide, and physician-led political activism in nepal, we describe three cases in wh ...200717720021
revitalizing the humanistic imperative in nursing education.this article describes a teaching strategy that focuses students' attention on the humanistic imperative in nursing practice. the humanistic teaching method provides a framework for adapting nursing courses to accommodate person-to-person, human-centered nursing care alongside scientific and technological competencies. through this approach, students integrate concepts such as humanism, existentialism, and phenomenology into patient interactions. in addition to producing a favorable effect on pa ...200717715806
prevalence of hepatitis b and c virus infections in children infected with hiv.we evaluated the prevalence and transmission mode of hepatitis b and c in an inner-city, pediatric cohort of human immunodeficiency virus (hiv)-infected persons, as well as the demographic characteristics of the cohort. hepatitis b or c was found in 13 (5.8%) of 228 children. this analysis suggests that chronic hepatitis is prevalent and should be routinely screened for in the pediatric hiv-infected population.200717712766
hair analysis in sled dogs (canis lupus familiaris) illustrates a linkage of mercury exposure along the yukon river with human subsistence food systems.the dog has been an important biomedical research model and hair samples from sled dogs could be used as a biomarker of exposure to metals. hair samples were used as a non-invasive indicator of mercury exposure in sled dogs fed commercial food and traditional village diets. sled dog populations living in rural new york and alaska were sampled in 2005 and 2006. total mercury (thg) content was determined on the entire hair sample in sled dogs from reference sites in north creek, new york and salch ...200717707466
monitoring the impact of influenza by age: emergency department fever and respiratory complaint surveillance in new york city.the importance of understanding age when estimating the impact of influenza on hospitalizations and deaths has been well described, yet existing surveillance systems have not made adequate use of age-specific data. monitoring influenza-related morbidity using electronic health data may provide timely and detailed insight into the age-specific course, impact and epidemiology of seasonal drift and reassortment epidemic viruses. the purpose of this study was to evaluate the use of emergency departm ...200717683196
human granulocytic anaplasmosis during pregnancy: case series and literature review.we describe the clinical and laboratory manifestations and pregnancy outcomes of 6 women who received a diagnosis of human granulocytic ehrlichiosis during pregnancy. human granulocytic ehrlichiosis did not seem to present in a fulminant fashion, and all treated patients had excellent responses to rifampin or doxycycline therapy. perinatal transmission was documented in 1 neonate, who responded well to treatment. there do not appear to be any long-term adverse sequelae in children born from thes ...200717682993
written consent for human immunodeficiency virus testing. 200717639644
raymond v. damadian, m.d.: magnetic resonance imaging and the controversy of the 2003 nobel prize in physiology or medicine.on october 6, 2003 the nobel committee announced that paul c. lauterbur, phd and sir peter mansfield, phd were awarded the nobel prize in physiology or medicine for their work on the development of magnetic resonance imaging. dr. raymond damadian was excluded and a controversy ensued.200717631325
the role of lizards in the ecology of lyme disease in two endemic zones of the northeastern united states.we examined the role of lizards in the ecology of lyme disease in new york and maryland. we collected data on vector tick infestations, measured lizard "realized" reservoir competence for the lyme disease spirochete borrelia burgdorferi, and estimated lizard population density. these data were incorporated into a model that predicts a host's ability to influence the prevalence of b. burgdorferi in the tick population, a primary risk factor in the epidemiology of lyme disease. published data on o ...200717626342
multistate outbreak of norovirus gastroenteritis among attendees at a family reunion--grant county, west virginia, october 2006.on october 17, 2006, the west virginia department of health and human resources (wvdhhr) was notified of an outbreak of acute gastroenteritis, characterized by vomiting and diarrhea, among attendees at a family reunion. the outbreak initially was reported by a group of attendees to their local health department in garrett county, maryland. the same day, the information was relayed to the grant county health department in west virginia and subsequently to wvdhhr. the reunion was held on october 1 ...200717625494
incident sexually transmitted infections among persons living with diagnosed hiv/aids in new york city, 2001-2002: a population-based assessment.objective/goal: to describe the incidence of 3 bacterial sexually transmitted infections (stis) among persons living with human immunodeficiency virus (hiv) infection and acquired immunodeficiency syndrome (aids) (plwha) in new york city (nyc) and to identify predictors for sti acquisition.200717621243
tracking human travel using stable oxygen and hydrogen isotope analyses of hair and urine.the stable oxygen and hydrogen isotope compositions of organic samples are increasingly being used to investigate patterns of animal migration. relatively few studies have applied these techniques to modern humans, despite a variety of potential forensic applications. we analyzed drinking water and food at two geographic locations, east greenbush, new york (usa) and fairbanks, alaska (usa), with different delta(18)o and deltad values for precipitation and tap water. foods varied widely in measur ...200717610246
the $5 man: the underground economic response to a large cigarette tax increase in new york city.we examined the mechanisms by which living in a disadvantaged minority community influences smoking and illegal cigarette sale and purchasing behaviors after a large cigarette tax increase.200717600270
incidence and persistence of staphylococcus aureus nasal colonization in a community sample of hiv-infected and -uninfected drug users.a longitudinal study of 282 community-based drug users was conducted from february 1999 through september 2000. both the incidence (15.0 cases per 100 person-years at risk; 95% confidence interval, 10.2-20.7 cases per 100 person-years at risk) and persistence of staphylococcus aureus carriage were increased among human immunodeficiency virus (hiv)-seropositive individuals.200717599312
symptomatic early neurosyphilis among hiv-positive men who have sex with men--four cities, united states, january 2002-june 2004.symptomatic early neurosyphilis is a rare manifestation of syphilis that usually occurs within the first 12 months of infection. most neurologic symptoms of early neurosyphilis result from acute or subacute meningitis, abnormalities in cranial nerve function, and inflammatory vasculitis leading to a cerebrovascular accident. symptomatic early neurosyphilis essentially disappeared in the united states after the introduction of penicillin treatment for syphilis in the late 1940s but reappeared in ...200717597693
acute human immunodeficiency virus infection in a breast-fed infant in new york city.acute human immunodeficiency virus (hiv) infection in a breast-fed infant is a rare diagnosis in developed countries. we present a six-month old girl with postnatally acquired hiv infection complicated by pneumocystis jéroveci pneumonia, cytomegalovirus pneumonitis and encephalopathy. her mother had tested negative for hiv during pregnancy. children infected by mothers during an acute seroconversion may have more rapid disease progression.200717596814
rapid hiv testing in emergency departments--three u.s. sites, january 2005-march 2006.approximately one fourth of the estimated 1 million persons living with human immunodeficiency virus (hiv) in the united states are unaware that they are infected with hiv and at risk for transmitting the virus to others. in april 2003, cdc announced a new initiative, advancing hiv prevention: new strategies for a changing epidemic, aimed at reducing barriers to early diagnosis of hiv infection and increasing access of persons infected with hiv to medical care and prevention services. a priority ...200717585288
lyme disease--united states, 2003-2005.lyme disease is caused by the spirochete borrelia burgdorferi and is transmitted to humans by the bite of infected blacklegged ticks (ixodes spp.). early manifestations of infection include fever, headache, fatigue, and a characteristic skin rash called erythema migrans. left untreated, late manifestations involving the joints, heart, and nervous system can occur. a healthy people 2010 objective (14-8) is to reduce the annual incidence of lyme disease to 9.7 new cases per 100,000 population in 1 ...200717568368
rapid vaccine distribution in nontraditional settings: lessons learned from project viva.with growing fear of a worldwide influenza pandemic, programs that can rapidly vaccinate a broad range of persons are urgently needed. vaccination rates are low among disadvantaged and hard-to-reach populations living within urban communities, and delivering vaccines to these groups may prove challenging. project viva1 (venue-intensive vaccination for adults), staffed by teams of nurses and outreach workers, aimed to deliver vaccines rapidly within disadvantaged neighborhoods in new york city. p ...200717563280
subcutaneous and omental fat expression of adiponectin and leptin in women with polycystic ovary syndrome.to assess message expression of adiponectin and leptin in visceral and sc fat in women with polycystic ovary syndrome (pcos) and in control women.200817562334
west nile virus activity--united states, 2006.west nile virus (wnv) is the leading cause of arboviral encephalitis in the united states. originally discovered in africa in 1937, wnv was first detected in the western hemisphere in 1999 in new york city. since then, wnv has caused seasonal epidemics of febrile illness and severe neurologic disease in the united states. this report summarizes provisional wnv surveillance data for 2006 reported to cdc as of april 3, 2007. during 2006, wnv transmission to humans or animals expanded into 52 count ...200717557072
computer-based multivariate economic analysis of neonatal-intensive-care-unit-based influenza vaccine administration to parents in a low-socio-economic, urban setting.trivalent inactivated influenza vaccine has been shown to reduce the number of influenza-related outpatient visits and hospitalizations of children up to 24 months of age. the american academy of pediatrics, centers for disease control, and advisory committee on immunization practices recommend that the influenza vaccine be administered to the first-person contacts of infants less than 6 months of age. however, the economic implications of increasing immunization rates by using the neonatal inte ...200717549758
association of polymorphisms in myeloperoxidase and catalase genes with precancerous changes in the gastric mucosa of patients at inner-city hospitals in new york.gastric carcinogenesis is a multistep process progressing from chronic gastritis, through glandular atrophy (ga), intestinal metaplasia (im) and dysplasia. we have previously demonstrated that minority patients at new york city hospitals are infected with a relatively virulent strain of h. pylori (hp) and that hp infection is associated with an increased incidence of precancerous changes in the gastric mucosa. nevertheless, precancerous changes are not observed in every hp-infected individual, s ...200717549373
plasma epstein-barr virus immunoglobulin a and dna for nasopharyngeal carcinoma screening in the united states.to examine the epstein-barr virus (ebv) iga and dna assays as a screening tool for nasopharyngeal carcinoma (npc) in a nonendemic us population.200717547994
advancing biocultural models by working with communities: a partnership approach.culture and human behavior are recognized today as major forces acting on human biological variation around the world. studies of the relationships between biology and processes, such as modernization, urbanization, and social stratification, are prominent in our journals and meetings. an ongoing study of the interrelationships between toxicant exposure (organochlorines, lead, and mercury), health, and culture among youth of the mohawk nation at akwesasne is located within this context and is us ...200717546616
promoting hcv treatment completion for prison inmates: new york state's hepatitis c continuity program.this article describes the development of a statewide program providing continuity of hepatitis c virus (hcv) treatment to prisoners upon release to the community. we discussed length of stay as a barrier to treatment with key collaborators; developed protocols, a referral process, and forms; mobilized staff; recruited heath-care facilities to accept referrals; and provided short-term access to hcv medications for inmates upon release. the hepatitis c continuity program, including 70 prisons and ...200717542460
does integrating viral hepatitis services into a public std clinic attract injection drug users for care?injection drug users (idus) are at high risk for multiple health problems, including human immunodeficiency virus (hiv), viral hepatitis, and sexually transmitted diseases (stds), and are likely to have poor access to health care. to more effectively serve high-risk clients, experts recommend that programs accessed by such client populations offer integrated services. in 2000, the new york city department of health and mental hygiene integrated viral hepatitis services (vaccine and screening) in ...200717542450
bioinformatics and human identification in mass fatality incidents: the world trade center disaster.victim identification initiatives undertaken in the wake of mass fatality incidents (mfis) where high-body fragmentation has been sustained are often dependent on dna typing technologies to complete their mandate. the success of these endeavors is linked to the choice of dna typing methods and the bioinformatic tools required to make the necessary associations. several bioinformatic tools were developed to assist with the identification of the victims of the world trade center attacks, one of th ...200717524061
assessment of adverse events associated with antiretroviral regimens for postexposure prophylaxis for occupational and nonoccupational exposures to prevent transmission of human immunodeficiency virus.to assess adverse events associated with antiretroviral regimens for human immunodeficiency virus (hiv) postexposure prophylaxis (pep), with a particular focus on the treatment combination of zidovudine, lamivudine, and tenofovir (zdv-3tc-tdf).200717520543
the transition from injection to non-injection drug use: long-term outcomes among heroin and cocaine users in new york city.to characterize heroin and cocaine users in new york city who have changed from injection to non-injection drug administration and to identify factors associated with long-term non-injection use.200717506155
poison control center surge capacity during an unusual increase in call volume--results from a natural experiment.poison control centers (pccs) play an integral role in the preparation for and management of poison emergencies. large-scale public health disasters, caused by both natural and human factors, may result in a drastic increase in the number of inquiries received and handled by pccs in short periods of time. in order to plan and prepare for such public health emergencies, it is important for pccs to assess their ability to handle the surge in call volume and to examine how the unusually large numbe ...200717484364
listeria monocytogenes fecal shedding in dairy cattle shows high levels of day-to-day variation and includes outbreaks and sporadic cases of shedding of specific l. monocytogenes subtypes.fecal shedding of listeria monocytogenes poses a risk for contamination of animal feed and agricultural environments and raw food at the pre-harvest stages of food production. to be able to reduce these risks it is critical to improve understanding of the epidemiology of l. monocytogenes shedding in feces. the objective of this study was to assess the daily variability of fecal shedding and its association with individual animal (lactation number and the day of current lactation) and environment ...200717481754
an overview of the 1976 new york academy of science meeting.in the late 1960s and early 1970s, endurance running was gaining popularity at an exponential rate. paul milvy organised the scientific and medical conference entitled 'the marathon: physiological, medical, epidemiological, and psychological studies' associated with 1976 new york marathon and sponsored by the new york academy of sciences to provide a forum for scientists to interact and to publish the proceedings to serve as a resource for future sports medicine research. the conference was a ma ...200717465588
human immunodeficiency virus counseling, testing, and referral of close contacts to patients with pulmonary tuberculosis: feasibility and costs.we aimed to increase human immunodeficiency virus (hiv) counseling, testing, referral (ctr), and knowledge of hiv serostatus of close contacts of tuberculosis patients and improve tuberculosis screening and treatment of hiv-infected contacts.200717435492
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