Publications

[pharmacologic study of the amebicidal and trichomonicidal activity of ornidazole (1-(2-hydroxy-3-chloropropyl)-2-methyl-5-nitroimidazole].		1976	188370
[infections transmitted in swimming pools].	public swimmingpools can be the source of infections due to micro-organism such as mycobacterium balnei, adeno and enteroviruses, the virus of plantar warts and molluscum contagiosum, the tric-agent of swimmingpool-conjonctivitis and pathogenic fungi. the transmission of trichomonas vaginalis is considered unlikely-water of pools, supposed to present satisfactory qualities by standard controls, was found to contain pathogenic staphylococci and pseudomonas aeruginosa. effective preventive measure ...	1976	186978
search for uro-genital tract infections in patients with symptoms of prostatitis. studies on aerobic and strictly anaerobic bacteria, mycoplasmas, fungi, trichomonads and viruses.	seventy-nine patients with symptoms of nonacute prostatitis and 20 healthy volunteers were examined for uro-genital tract infection with bacteria, mycoplasmas, fungi, trichomonads and viruses. no differences in the results of the bacterial cultures were found between the patients and the controls. in only a few cases were established urinary tract pathogens found, but in no instance were these findings reproducible in later specimens. the cultures of the expressed prostatic fluids and the sample ...	1975	175434
snythesis and antiprotozoal activity of nitro derivatives of 2, 2'-biimidazole.	we synthesized a series of 2,2'-biimidazoles with different substituents and screened them against entamoeba histolytica, trichomonas vaginalis and giardia muris. a 5-nitro group is necessary for the inclusion of activity and an amino group exercises favourable effect on in vivi activity.	1975	167793
chemotherapeutic nitroheterocycles. 18. 2-(5-nitro-2-imidazolylmethylene)-1-indanones, -1-tetralones, and -acetophenones substituted by aminoalkoxy groups.	2-(5-nitro-2-imidazolylmethylene)-1-indanones, -1-tetralones, and -acetophenones substituted by aminoalkoxy groups and related compounds (41-69, table ii) were synthesized and their antimicrobial activities were evaluated (table iii). some of these compounds (e.g. 47, 52, and 59) suprisingly exhibited a broad antibacterial spectrum including proteus species and pseudomonas aeruginosa. extraordinary antitrichomonal activities could also be observed in vitro (mic of compound 59, 0.0004 pg/ml) and ...	1975	166185
value of papanicolaou-stained smears in the diagnosis of trichomoniasis, candidiasis, and cervical herpes simplex virus infection in women.	in the diagnosis of trichomoniasis papanicolaou-stained cervical smears gave marginally better results than cultures of vaginal secretion; stained cervical smears and wet films of vaginal material gave similar results. culture of vaginal secretion on sabouraud's medium gave the best results in the diagnosis of candidiasis; papanicolaou-stained smears gave significantly fewer positive results than either cultures or gram-stained vaginal smears. papanicolaou-stained smears were reported as positiv ...	1975	165860
etiology of nongonococcal urethritis.	chlamydia trachomatis was isolated from the urethra from 48 (42 per cent) of 113 men with non-gonococcal urethritis (ngu), four (7 per cent) of 58 without overt urethritis, and 13 (19 per cent) of 69 with gonorrhea. postgonococcal urethritis (pgu) developed in 11 of 11 men who had c. trum antibody to c. trachomatisis developed. the immunotype specificity of chlamydial antibody corresponded to the immunotype isolated. among culture-negative patients. chlamydial antibody prevalence correlated with ...	1975	165407
evaluation of hysterectomized women seen at a clinic for treatment of sexually transmitted diseases.	thirty-one women who had had total hysterectomies, seen in a venereal disease clinic, were interviewed and examined. thirteen (31%) of the 31 women had acquired one or more venereal infections after hysterectomy. the diseases, listed in order of decreasing frequency, were trichomoniasis (four cases), gonorrhea (three), early latent syphilis (three), vaginal candidiasis (three), secondary syphilis (two), late latent syphilis (two), and condyloma acuminatum (one). these results indicate that clini ...	1979	156406
[possibility of staining trichomonas vaginalis by acridine orange (author's transl)].		1978	151598
parasitic infections and the genitourinary tract.		1975	124862
[phagocytic ability of trichomonas vaginalis donné].		1979	118590
[effect of microorganisms on survival of trichomonas vaginalis in physiological fluid].		1979	117638
vaginal discharge and sexually transmitted diseases.		1978	108216
chlamydia trachomatis cervicitis in gynecologic outpatients.	symptoms suggestive of a lower genital tract infection (lgti) are common complaints in women who consult gynecologists. sexually transmitted microorganisms, such as chlamydia trachomatis. neisseria gonorrhoeae, and trichomonas vaginalis, are responsible for a substantial proportion of lgti. this study was performed to establish the frequency of lgti caused by c trachomatis in women attending a gynecologic outpatient clinic. of 170 women with lgti, 32.9% harbored one or more of these organisms: c ...	1978	104212
in vitro sensitivity of trichomonas vaginalis and candida albicans to chemotherapeutic agents.	strains of fresh clinical isolates of trichomonas vaginalis and candida albicans have been tested in vitro for their sensitivity to eight drugs used in the therapy of monilial and trichomonal vaginitis. three of the chemotherapeutic agents, chlorchinaldol, clotrimazole and broxyquinoline were effective against both organisms. tinidazole and metronidazole were active against t. vaginalis. the strains of c. albicans were also sensitive to trichomycin, natamycin and nystatin. tinidazole was the mos ...	1978	102108
[non-gonorrhoic urethritis caused by trichomonas vaginalis].		1978	101829
microbiology of the vagina in children: normal and potentially pathogenic organisms.	vaginal cultures from 100 healthy girls, 2 months to 15 years of age, were examined for the presence of normal and potentially pathogenic microorganisms. corynebacterium vaginale, yeast species, and genital mycoplasmas were isolated from vaginal cultures from 13.5 %, 28%, and 28% of the girls examined, respectively. colonization with these organisms was not associated with signs or symptoms of vaginitis. neisseria gonorrhoeae was isolated from a 4-year-old with purulent vaginitis. trichomonas va ...	1978	98750
[personal prophylaxis of venereal diseases].		1978	97875
[the induction and disappearance of complement-fixing antibodies in the blood serum of experimental animals under the antigenic action of trichomonas vaginalis, t. hominis and t. tenax].	for studying the dynamics of induction and disappearing of complement-fixing antibodies (cfa) specific to trichomonas vaginalis, t. hominis and t. tenax we have immunized rabbits intravenously with live individuals of the protozoa as well as intravenously, intramuscularly and subcutaneously with individuals killed at 56 degrees c. each method of immunization was carried out by 5 inoculations with intervals of 10 days. for carrying out quantitative complement fixation we have taken blood from the ...	1979	95819
[comparison of soluble antigens of 2 cultured clones, of different age, from the same strain of a flagellate parasite: trichomonas vaginalis donné, 1837].	antigenic analysis released indications that there seemed to be a qualitative difference between two clones (a2, a3) as well as between a young clone a2 and an old one (the latter having been in culture for 12 months) both of them originating from the same initial clone. such differences are reduced to quantitative level by the results of cross absorptions. antigenic variations mentioned by the previous authors are to be questioned.	1979	93034
rapid staining technique for trichomonas vaginalis. preliminary report.	a simple, rapid, staining method for the identification of trichomonas vaginalis has been tested on cultured trichomonads and specimens of vaginal discharge. fifty-eight stained slides of vaginal discharge were examined and trichomonads were correctly identified in the 31 specimens from patients with confirmed vaginal trichomoniasis. no false-positive results were obtained. this staining procedure could prove a useful addition to wet-film and cultural methods.	1979	90513
[times for the microscopy of trichomonas vaginalis inocula].		1979	85766
[round forms of trichomonas vaginalis. demonstration using vital staining and phase contrast. morphological differentiation in practice].		1978	84442
isolation of trichomonas vaginalis resistant to metronidazole.		1978	80664
[pictures of t. vaginalis obtained by a modified method of staining cytological preparations].		1977	75611
a study of the possible value of acridine orange-o strain in the diagnosis of trichomonas vaginalis infection.		1977	66993
[study of the method of direct immunofluorescence for differentiation of serotypes of trichomonas].	it is possible to differentiate the serotypes of trichomonas vaginalis by the direct immunofluorescent method using the tupe-specific antisera labelled with fluorescin-isothiocyanate. the most decisive factor in expressing the degree of induced fluorescence is the serotype of the protozoa. evans blue, which has an intensive red fluorescence, totally eliminates the green autofluorescence of t. vaginalis and does not influence the induced specific fluorescence.	1975	66657
the fine structure of cells of trichomonas vaginalis donné obtained from the exponential phase of growth and from stationary cultures.	in cells of trichomonas vaginalis in logarithmic phase of growth (log. t. vaginalis) the number of free cytoplasmic ribosomes was higher than that in cells from stationary cultures (stat. t. vaginalis). polyribosomes closely surrounding the chromatic granules were present in equal amounts in both categories fo cells, which indicates that they have specific functions and are not directly involved in the protein synthesis of the growing cell. the volume of the golgi region and of the food vacules ...	1976	60874
comparison of four techniques for the routine diagnosis of trichomonas vaginalis infection.	specimens from 495 patients attending johannesburg hospitals and family planning clinics were examined for trichomonas vaginalis by microscopy of giemsa (gs), papanicolaou (pap), and acridine-orange (ao) stained smears, and by culture in feinberg-whittington medium. culture, pap and gs stained smears from vaginal swabs yielded fewer positives than ao stained smears. although pap-stained cytological smears gave the highest number of positives, in 30% of these cases the presence of t.vaginalis cou ...	1976	58872
clostridium defficiel in the urogenital tract of males and females.	a study of the occurrence of clostridium difficile in the urogenital tract of males and females revealed higher isolation-rates in patients attending the special (venereal-disease) clinic than in patients attending family-planning and urological clinics. the presence of cl. difficile in patients with venereal diseases is being investigated to see if the organism is simply an opportunist infecting a urethra disturbed by some antecedent disease, or if it is perhaps a primary cuase of disease.	1975	48610
effects of 2,4-dinitrophenol on trichomonads and entamoeba invadens.	1. 2,4-dinitrophenol (2,4-dnp) in substrate level concentrations (200 microm-1 mm) temporarily inhibits h2 production by tritrichomonas foetus and trichomonas vaginalis as well as the accumulation of metronidazole, dependent on its reduction by the two trichomonad species and by entamoeba invadens. 2. 2,4-dnp competes for the reducing equivalents which are necessary for h2 production or for the reduction of metronidazole, thereby inhibiting these processes. 2,4-dnp is reduced to 2-amino, 4-nitro ...	1979	45533
statistico epidemiological study of changes in the vaginal flora of contraceptive pill users in alexandria.	a stratified random sample of 1000 women with proportionate allocation according to district of residence was taken from normal females living in alexandria, egypt, and attending family planning centers in order to understand social-pathological changes in the vaginal flora of oral contraceptive (oc) users. cases were examined over 18 months, and all cases were given a combined oc. bacteriology and ph changes in vaginal flora were determined after 18 months. results of the bacteriological exa ...	1979	44312
a simple medium for in vitro culture of trichomonas vaginalis.		1979	41896
trichomonas vaginalis: nadh oxidase activity.		1979	37100
[conference held in warsaw on 3rd april 1976 "standardization of methods of identification of t. vaginalis"].		1978	31733
activity-electroreduction relationship of antimicrobial metronidazole analogues.		1978	25969
synthesis and biological activity of some vinyl-substituted 2-nitroimidazoles.	in previous studies 1-methyl-2-nitro-1h-imidazole-5-carboxaldehyde and 1-methyl-2-nitro-5-vinyl-1h-imidazole were found to posses interesting antimicrobial activities. we have now prepared some 2-nitro-1h-imidazoles in which the 5-vinyl chain bears selected functional groups (cho, coch3, no2) as well as nitrogen-condensation derivatives of the carbonyl functions. furthermore, 5-methyl-2-nitro-1-vinyl-1h-imidazole has been synthesized. all the compounds, and some intermediates, have been assayed ...	1977	16132
microbiology of the female genital tract during pregnancy and parturition.		1976	10196