Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
|---|
| comparison of ornidazole and tinidazole in single-dose treatment of trichomoniasis in women. | a comparison is made between oral ornidazole in a single 1-5 g dose and tinidazole given in a 2 g dose using a double-blind technique. all the 45 women with trichomonas vaginalis infection who were treated with ornidazole were cured. in the tinidazole-treated group 41 out of 43 women had negative cultures after treatment. tolerance was good in both groups. | 1977 | 326349 |
| antibiotics produced by streptomyces olivaceus 142. ii. isolation, purification and activity spectrum of antibiotic wr 142-fpg. | a method of isolating antibiotic wr 142-fpg from the fermentation broth and mycelium of mutant fpg of the strain streptomyces olivaceus 142 has been developed. the method of purification of the active substance and activity spectrum agains microorganisms are described. some of the basic properties of two preparations are given: a) the preparation designed i, partly purified, containing a peptide moetye and b) the preparation designed ii, which is a homogeneous chromatographically preparation wit ... | 1977 | 326221 |
| [in vitro action of mepartricin in combination with chlortetracycline]. | the microbiological activity of a mepartricin + chlortetracycline hydrochloride association was evaluated on the principal agents causing cervico-vaginal infections. beside confirming the antimycotic and antiprotozoal efficacy of mepartricin, is was possible to demonstrate an absence of antagonism with chlortetracycline. on the other hand, in some cases this antibiotic could potentiate the antitrichomonas effect of mepartricin. | 1977 | 324437 |
| single dose of two grams of metronidazole for trichomonas vaginalis infection. | in this study, 243 women with symptomatic trichomonal vaginitis were treated with eight 250 mg. tablets of metronidazole for themselves, and eight tablets were given to each of their male consorts. they were given instructions to ingest "all eight in a row" and "avoid alcohol for 48 hours." ninety-five per cent of 203 women that returned for re-examination were cured. this single-dose treatment is effective, well tolerated, and less expensive than current recommended dosages. | 1977 | 324287 |
| ornidazole: a new antiprotozoal compound for treatment of trichomonas vaginalis infection. | a new anti-protozoal compound, ornidazole, a derivative of nitroimidazole, was given in a single 2 g dose to 20 women with trichomonas vaginalis infection. all the women were cured, but they suffered some side-effects. plasma levels of ornidazole reached a peak five to eight times higher than minimum inhibitory concentrations and exceeded this level for at least 36 hours. it is therefore possible that a smaller dose might have had an adequate trichomonicidal effect and fewer side-effects. furthe ... | 1977 | 321095 |
| [prevention and epidemiology of trichomonal vaginitis in women treated in gynecological departments]. | the purpose of the work is to present the results of prophylactic actions used in the departments of the institute of obstetrics and gynecology of the medical academy in bia ł ystok giving reasons for changes and modifications concerning the present state of procedures. at the same time, attention has been paid to some epidemiological factors of trichomoniasis in women treated in gynecological departments for various diseases of the female genital organ. women treated in the departments of the i ... | 1979 | 318114 |
| [comparative studies on trichomonas vaginalis in the scanning electron microscope]. | different strains of trichomonas vaginalis isolated from the vagina of women with trichomoniasis were used in these investigations. the cultures were carried out on modified cplm and roiron media. individuals at the highest phase of logarithmic growth underwent the observation. preparations to be evaluated in scanning electron microscope ( jeol - jsm -s1) were made from a condensed culture containing 500,000 individuals per ml. each time, microscopic pictures obtained after washing, demucination ... | 1979 | 318113 |
| [incidence of trichomonas vaginitis among women in the białystok region]. | nine-year period of examinations, carries out within the former borders of the bia ł ystok province including 332 774-391 959 women above 20 years of age, was subjected to analysis. from this group, about 85000-109000 women underwent microbiological examinations. an increasing number of microbiologically examined women corresponds to increasing detectability of trichomoniasis between 1971-1972. from that time on, a distinct decrease in detectability has been observed. detailed analysis of tricho ... | 1979 | 318112 |
| [the culture of trichomonas vaginalis and its incidence in vaginitis]. | direct microscopic and cultural examination of 151 cases of vaginitis have been applied. trichomonas vaginalis observed in 22 cases by direct microscopic examination and isolated in 42 cases by cultural method. candida sp isolated in 46 cases. all patients were treated. | 1979 | 318031 |
| [effect of ozone, iodine and bromine in the water on trichomonas vaginalis under laboratory conditions]. | 1979 | 317360 | |
| in vivo and in vitro studies of tinidazole in trichomonas vaginalis infection. | a total 787 patients with complaints of vaginal discharges were examined, of which 106 patients were found to be positive for trichomonas vaginalis by the normal saline method, and 114 patients were positive by the culture method. in the in vivo series, 55 patients were treated with a single dose of 1.8 gm of tinidazole, and with a follow-up examination 7 days there after. for the in vitro study 55 swab specimens were cultured to study the tinidazole sensitivity of trichomonas vaginalis. the sur ... | 1979 | 317171 |
| do oral contraceptives inhibit trichomonas vaginalis? | usage of oral contraceptives was recorded for 114 women with trichomoniasis, 179 women with yeast infection, and 333 women with gonorrhea. usage by each group was compared with that of 517 women with no genital infection. the proportion of oral contraceptive users was significantly smaller among those with trichomoniasis (p less than 0.002), significantly larger among those with yeast infection (p less than 0.001), but not significantly different among those with gonorrhea. among 80 women with b ... | 1979 | 316933 |
| screening for trichomonas vaginalis infection by use of acridine orange fluorescent microscopy. | the acridine orange test for detection of trichomonas vaginalis in smears has been adapted for delayed examination of specimens. mailed-in slides stained by acridine orange were compared with on-site wet mounts; the acridine orange test detected 96% of all positives, whereas only 76% were detected by wet mounts. in a similar comparison with papanicolaou smears, the acridine orange test detected 89% as compared with 67% detected by papanicolaou smears. | 1979 | 316932 |
| [criteria of clinical evaluation of antitrichomonal agents]. | 1979 | 316618 | |
| [non-gonorrheal urethritis in men. clinical aspects, diagnosis and treatment]. | 1979 | 316550 | |
| [comparison of the effectiveness of antitrichomonal agents in limited trichomonas vaginitis]. | 1979 | 316235 | |
| [comparison of urine and vaginal samples in the diagnosis of trichomonas vaginalis (author's transl)]. | 1979 | 316168 | |
| [new fluorescence microscopic technic for the identification of trichomonas vaginalis]. | a new fluorescent dye for the identification of trichomonas vaginalis is described. specimens under investigation were mixed with 4',6-diamidino-2-phenylindol (dapi) and examined using white light and uv-light. the combined use of the two techniques allows to recognize the mobile non fluorescing and the dead intensive yellow fluorescing trichomonads. devitalized epithelial cells, bacteria and leucocytes in contrast to living trichomonas are stained yellow in a few minutes. this is of diagnostic ... | 1979 | 315935 |
| metronidazole-resistant trichomonas vaginalis. | a 36-year-old woman with symptomatic metronidazole-resistant trichomonal vaginitis for 10 years had a total of 22 courses of treatment with either metronidazole or tinidazole according to different schedules. the minimum trichomonicidal concentration of metronidazole for the strain of trichomonas vaginalis isolated from the patient was 160 microgram/ml compared with 1.25-10 microgram/ml for other freshly isolated strains. the former strain also showed a definitely decreased sensitivity to ornida ... | 1979 | 315809 |
| [association between trichomonas vaginalis and some types of lesions of the uterine neck based on data collected in the quinquennium of 1974--1978]. | in our statistic the number of cases of vaginal trichomoniasi in which discariosi, displasie, metaplasie are found are represented in about 40%. while 37,5% of women affected with neoplastic lesions had trichomonas vaginalis. it is certain that in the presence of flogosi from trichomonas vaginalis we meet more frequently than normal, atipie cellulars and that often an exact valutation of this lesion is put back to an exam after the recovery of the trichomonas vaginalis, because fortunately, more ... | 1979 | 315781 |
| [statistical observations on the incidence of trichomonas vaginalis in the female population of terni from 1974 to 1978]. | the casuistics refers to 1646 cases equal to 20,5% of vaginal trichomoniasis in a total of 7996 pap tests examined in the service of anatomy and histology pathology in the hospital of terni. the exams of the incidences of trichomoniasis in the various age classes, reveals that the main frequency is found in the 2nd., 3rd., 4th decades of life, that is in the period of maximum sexual attivity. vaginal trichomonas is rarer before puberty and after the menopause. | 1979 | 315780 |
| the use of phenolphthalein monophosphate to enhance bioautography with trichomonas vaginalis. | 1979 | 315402 | |
| diagnosis of trichomonas vaginalis infection. | 1979 | 314995 | |
| biological assay of potential trichomonacides in vitro using a counter apparatus. | utilising the accuracy and speed of a coulter counter for cell counting and sizing, a new method of antimicrobial assay has been developed in which the potency of inhibitors is calculated on a mol/cell basis. a total of 72 potential trichomonacides were screened against trichomonas vaginalis and the ed50 value estimated for 27 of the most interesting and potent compounds. the ed50 value for metronidazole was a mean of 5.12 fmol/cell and only 6 compounds were more potent. after the nitroimidazole ... | 1978 | 314804 |
| [role of trichomonas vaginalis in maintaining a microbial infection]. | 1979 | 314758 | |
| [evaluation of the effect of calendula officinalis and echinacea angustifolia extracts of trichomonas vaginalis in vitro]. | 1979 | 314706 | |
| a study on the diagnostic methods for trichomonas vaginalis infection. | a comparison of the sensitivity of the wet smear, papanicolaou's stained smear, and culture in cystein-peptone-liver-maltose (cplm) medium for the diagnosis of t. vaginalis infection was undertaken in 1, 197 female subjects, both with and without gynaecological disorders. the wet smear method gave 15.5% positives, culture method, 16.5% positives and papanicolaou's stained smear 6.7% positives. all positive cases by papanicolaou's method or wet smear method were positive by the culture method. th ... | 1979 | 314672 |
| prevalence of trichomonas viginalis in selected groups of the population in bangkok. | 1979 | 314671 | |
| structure of trichomonads as revealed by scanning electron microscopy. | a scanning electron microscope (sem) study of hypotrichomonas acosta (moskowitz), trichomonas vaginalis donné, pentatrichomonas hominis (davaine), and tritrichomonas foetus (riedmüller) provided new information about the structure of the periflagellar canal; emergence of the flagella from the cell body; structure of the undulating membrane; and position, shape, and size of the pelta. of special interest were the spatial relationships of the attached part of the recurrent flagellum and the access ... | 1979 | 314517 |
| lack of obligatory association between mutagenic and antitrichomonal effects of metronidazole. | 1979 | 314505 | |
| [non-gonococcal urethritis in men: epidemiology and etiology]. | 1979 | 314123 | |
| [the study of trichomonas vaginalis in urological field--tenth report--recurrent emergency of trichomonas vaginalis in the fluid content of hydrocele testis--a case report (author's transl)]. | 1979 | 314011 | |
| vaginal microbial flora in normal young women. | 1979 | 313832 | |
| [significance of variations in the size of trichomonas vaginalis in patients with dysplasia, intrapithelial and invasive planocellular carcinoma of the uterine cervix]. | the study of the size of trichomonas vaginalis in 100 patients with dysplasia and intraepithelial or invasive planocellular carcinoma of the uterine cervix and in 100 controls with trichomoniasis alone has shown that the parasites are of a significantly smaller diameter in carcinoma in situ (9.57 +/- 0.35 mu) and invasive carcinoma (10.44 +/- 0.66 mu) than in dysplasia (13.71 +/- 0.35 mu). the analysis of the variance has shown that this difference is statistically significant. in the control gr ... | 1979 | 313489 |
| [chronic trichomonas infections in the male. their significance for fertility disorders]. | 1979 | 313127 | |
| [synthesis of antimicrobial agents. ii. synthesis of 1,8-naphthyridine derivatives and their activities against trichomonas vaginalis (author's transl)]. | 1979 | 312317 | |
| strain of trichomonas vaginalis resistant to metronidazole and other 5-nitroimidazoles. | a strain of trichomonas vaginalis (ir-78), recently isolated from a patient afflicted with recurrent symptomatic trichomoniasis, showed resistance to metronidazole, tinidazole, and nimorazole in vitro as well as in vivo. in a serial dilution test using cysteine monohydrochloride-peptone-liver infusion-maltose medium, t. vaginalis ir-78 was only resistant under aerobic conditions. under anaerobic conditions it was as susceptible as the normal reference strain. the minimal lethal concentrations of ... | 1979 | 311617 |
| [in vitro studies of the spermatozoa response to trichomonas vaginalis]. | 1979 | 311485 | |
| enhancement versus tumor resistance induced by different levels of immunodepression in balb/c mice with protozoan infections. | 1979 | 311287 | |
| lipid synthesis by trichomonas vaginalis. | 1978 | 310661 | |
| an electron microscopic investigation on the pathogenesis of human vaginal trichomoniasis. | the fine structure of trichomonas vaginalis and its acid phosphatase activity in the vaginal medium was investigated with the aid of the electron microscope. the relationship among trichomonads, desquamated epithelial cells, macrophages and bacteria was examined with special attention directed towards their phagocytic behavior. acid phosphatase activity was observed in the golgi apparatus, phagolysosomes and in the chromatic granules of trichomonas vaginalis. macrophages and leukocytes also exhi ... | 1978 | 310614 |
| evaluation of the indirect hemagglutination technique for study of trichomonas vaginalis infections, particularly in men. | the indirect hemagglutination (iha) technique was evaluated for use in the serologic study of infection with trichomonas vaginalis. the iha test showed that sera from 88% of women attending a venereal disease clinic had antibody to t. vaginalis. the antibody frequency and titers were highest in women who had documented infections due to t. vaginalis. serologic and cultural evidence of recent or active trichomonal infection was found in 11% of 85 men who had nongonococcal urethritis, but was abse ... | 1978 | 310166 |
| [vagicult set for detection of trichomonas vaginalis and yeasts in vaginal smears]. | 1978 | 310116 | |
| effect of oxygen and carbon dioxide on the growth of trichomonas vaginalis and tritrichomonas foetus. | 1978 | 309937 | |
| risk of cervical cancer among an electrocoagulated population. | in finland an organized mass screening program covers the total female population. based on the material (429,832) from a nationwide mass screening registry it was estimated that the female population not subjected to electrocoagulation of the uterine cervix (362,511) had a sixfold risk of frankly invasive carcinoma, a fourfold risk of carcinoma in situ or dysplasia of high degree, and a twofold risk of dysplasia of low degree as compared with the female population subjected to electrocoagulatio ... | 1978 | 307910 |
| [trichomonas vaginalis]. | 1978 | 307485 | |
| [study of the prostatic contents in the detection of asymptomatic trichomoniasis in men]. | 1978 | 307262 | |
| immune response and degree of protection in mice immunized with trichomonas vaginalis antigen. | the immune response and degree of protection of mice immunized with t. vaginalis sonicated antigen injected by intraperitoneal route, intraperitoneal and intravaginal only has been studied. humoral response has been evaluated by indirect immunofluorescence and agglutination techniques; moreover, cytotoxicity of vaginal secreta has been investigated. cellular response has been evaluated by stimulation of peripheral lymph-node cells and spleen lymphocytes with t. vaginalis antigen. it has been obs ... | 1977 | 306940 |
| absence of detectable local antibody in genitourinary tract secretions of male contacts of women infected with trichomonas vaginalis. | samples of semen and urine were obtained from 37 male contacts of women with proved trichomonas vaginalis infection; on culture, eight (22%) of the men were shown to harbour the parasite. however, significant amounts of antitrichomonal antibody were found in only two of these samples, and the amounts present were very small. a further 10 samples were tested but none was found to contain antibody. the asymptomatic nature and low parasite numbers commonly described in infections in men is thus unl ... | 1978 | 306858 |
| [survival of trichomonas vaginalis in original cuture and its cultural adherence (author's transl)]. | 1978 | 306289 | |
| abnormal forms of trichomonas vaginalis. | abnormal forms of trichomonas vaginalis have been demonstrated by both conventional and scanning electron microscopy after inoculation of media with clinical material from cases of trichomonal vaginitis. twenty-six cases of vaginitis have been studied; 10 of them showed the abnormal forms of trichomonads after growth in a modification of the medium described by bushby and copp (1955), while 16 showed only normal forms. | 1978 | 305810 |
| metronidazole and tinidazole in a single large dose for treating urogenital infections with trichomonas vaginalis in men. | seventy-three men with urogenital trichomonal infection were treated with a single daily dose of 1 g tinidazole or 1.5 g metronidazole. both treatments gave satisfactory results. wives who were also infected with trichomonas vaginalis, were less likely to have a recurrence of the infection after their husbands had been given either drug. | 1978 | 305809 |
| secnidazole. a 5-nitroimidazole derivative with a long half-life. | the therapeutic activity of a single 2 g dose of secnidazole was studied in patients with urogenital trichomoniasis. in 140 patients, 97% were cured and the drug was well tolerated. in the laboratory, tests on sensitivity were made and the minimal inhibitory concentration (mic) and the minimal trichomonacidal concentration (mtc) were determined on cultures that had recently been isolated at the clinic, and the pharmacokinetic properties of secnidazole in man were compared with those of tinidazol ... | 1978 | 305808 |
| studies on strain sensitivity of trichomonas vaginalis to metronidazole. | ninety-four strains of trichomonas vaginalis isolated from unselected patients in vienna during the period from november 1975 to november 1975 were subjected to sensitivity tests against metronidazole in vitro and in vivo. nearly 90% of the isolates examined showed in vitro growth inhibition at concentrations of 0.4 to 1.6 microgram metronidazole/ml and only about 10% at concentrations of less than 0.4 microgram/ml. all isolates showed some inhibition of growth after incubation for 48 hours with ... | 1978 | 305807 |
| microbes associated with leucorrhoea. | 1977 | 305453 | |
| [in vitro effects of tinidazole on selected microorganisms of vaginal ontocenosis in trichomonas vaginitis]. | 1977 | 305169 | |
| [antitrichomonal action of new beta-diethylaminethyl acetophenone, isoxazole and chromanone ethers]. | 1977 | 305168 | |
| [effect of vaginal microorganisms on the epithelium of the vaginal part of the uterus]. | 1977 | 305167 | |
| [diagnosis of trichomonas vaginitis by means of the carbonate agglutination reaction]. | 1977 | 305166 | |
| [behavior of the common part of the uterus in guinea pigs following infection with t. vaginalis. i. mast cells]. | 1977 | 305165 | |
| [comparison of the population density of t. vaginalis donné in cultures with fungi strains isolated from cases of trichomonadosis or trichomonadosomycosis]. | 1977 | 305164 | |
| [effect on t. vaginalis of vaginal contents following electrocoagulation of the uterine neck]. | 1977 | 305163 | |
| [penetration by t. vaginalis of female uterine cavity]. | 1977 | 305162 | |
| [reproduction of vaginal trichomonas depending on the conditions of their habitat]. | 1977 | 305161 | |
| [rosette and vegetative form of trichomonas vaginitis in women of the wrocław district and the wrocław district management of state railroads examined in the years 1973-1975]. | 1977 | 305160 | |
| [t. vaginalis donné variability in axenic cultures evaluated in scanning electron microscope]. | 1977 | 305159 | |
| [morphological variability of t. vaginalis in vivo and in vitro]. | 1977 | 305158 | |
| trichomonas vaginalis: effect of tinidazole on ultrastructure in vitro. | 1977 | 304415 | |
| [some questions on the relationship between vaginal biocenosis and the course of pregnancy (proceedings)]. | 1977 | 304384 | |
| [trichomonas vaginalis and cytological findings (author's transl)]. | the detection of trichomonas vaginalis by the method of the papanicolaou smear has proven as suitable. alterations of surface cells in the presence of trichomonas vaginalis are described, and causal relations between atypic cells and trichomonas vaginalis are discussed. from a total of 13000 in investigations of cancer screening in 1975, an infection with trichomonas vaginalis was found in 850 cases = 6,69 p.c. in contrast to this result 28 p.c. of the 116 patients with cancer of precancer of th ... | 1977 | 303893 |
| [bacteriostatic, antimycotic and antitrichomonal effects in vitro of a new antineoplastic drug, ledakrin, polfa]. | 1977 | 303764 | |
| interference of human spermatozoal motility by trichomonas vaginalis. | human spermatozoa were exposed to concentrations of live trichomonas vaginalis varying from 10(4) to 10(7) organisms per ml. a striking decrease in spermatozoal motility ensued. the possible role of trichomoniasis in human reproductive failure is considered. | 1977 | 303705 |
| [isolation of trichomonas vaginalis]. | 1977 | 303171 | |
| [trichomonas vaginalis incidence in the material of the hygiene centre of bratislava city (1970-1975) (author's transl)]. | 1977 | 302731 | |
| [study of trichomonas vaginalis resistance to metronidazol spofa (author's transl)]. | 1977 | 302730 | |
| biological properties and clinical application of propolis. ii. studies on the antiprotozoan activity of ethanol extract of propolis. | solutions of the ethanol extract of propolis (eep) have shown a lethal effect on trichomonas vaginalis in vitro. similar lethal action was exhibited by eep after a 24-h contact with toxoplasma gondii. | 1977 | 302709 |
| [diagnosis of asymptomatic trichomonas vaginalis in men]. | 1977 | 302456 | |
| comparative studies on the trichomonacidal activity of 5-nitroimidazole-derivatives in mice infected s.c. or intravaginally with t. vaginalis. | the trichomonacidal efficacy of metronidazole, tinidazole, nimorazole and ornidazole was studied in mice infected s.c., or for comparison purposes intravaginally. in both test systems, the drugs revealed nearly the same order of efficacy, whereby the compounds showed a marked decrease of activity when analyzed in s.c. infected mice. | 1977 | 302218 |
| [presence of trichomonas vaginalis in the urethra and bladder of women with colpitis trichomonalis]. | 1977 | 300992 | |
| [trichomonas vaginalis in patients with non-gonorrheal inflammation of the urogenital tract and in healthy subjects]. | 1977 | 300889 | |
| comparisons between direct microscopic and cultural methods for recognition of corynebacterium vaginale in women with vaginitis. | the frequency with which clue cells could be detected in gram-stained vaginal smears and/or cervical papanicolaou (pap) smears was compared with the frequency of corynebacterium vaginale (haemophilus vaginalis) isolation in a group of 236 female patients, of whom 221 had vaginitis. vaginal clue cells were found most often in women from whom c. vaginale was isolated (p = 0.00006) whereas, conversely, clue cells in cervical pap smears were reported more frequently in women with negative cultures f ... | 1977 | 300740 |
| [trichomoniasis. physiopathology and therapy]. | based on many years' experience with trichomonas vaginalis the author comes to the conclusion that trichomonads are much more common than expected. therefore the possibility of trichomoniasis shoudl be taken into account not only when discharge is found in females or persistent urethritis in males, but also in other affections. remote reactions may occur in either sex, e.g. prostatis or adnexitis. sterility is sometimes due to trichomonas vaginalis. apart from classical pictures in either sex ar ... | 1977 | 300704 |
| additional uses of polyvinyl alcohol (pva) in the fixation and staining of parasitic protozoa. | 1977 | 300520 | |
| microbiology of the female reproductive tract. v. changing patterns within one decade in a french canadian population. | 1977 | 299891 | |
| trichomoniasis--incidence in pill users and associated pap smear abnormalities. | the occurrence of trichomonas vaginalis in pill users and nonusers was studied by examining 1163 cervico vaginal smears. there were twice as many pill users as nonusers and a significant number of asymptomatic carriers. the cytologic findings ranged from normal through inflammatory and dyskaryotic changes to those with malignant features. the majority, however, belonged to the benign end of the spectrum of epithelial atypias. significant observations are that the greater incidence of trichom ... | 1979 | 263423 |
| the genesis of amniotic fluid infections. | amniotic fluid infections manifested by an inflammatory response in the extraplacental membranes and subchorionic plate of the placenta are a common phenomenon thought to be due in most cases to ascending bacterial infections via intact membranes. fatal spread to the fetus is much less common and more likely to occur in underprivileged communities. the probable reasons are nutritional deprivation in the mother or both, leading to production of a liquor with diminished ability to suppress bacteri ... | 1979 | 261765 |
| [randomised investigations of some tyrolean swimming pools for the presence of trichomonas vaginalis and pathogenic fungi (author's transl)]. | trichomonads were not demonstrated either microscopically or by culture in water samples from 15 public open air swimming pools in the tyrol. on the other hand, a small number of pathogenic fungi (candida albicans, trichophyton mentagrophytes, tr. verrucosum) were cultured from pool water with a free chlorine content of less than 0.35 mg/l (dpd 1). dermatophytes could also be demonstrated by cultures of the coatings on the surfaces of tiles in the showers, and of pool surrounding-and cabin tract ... | 1975 | 239503 |
| 1-alkyl-2-nitroimidazol-5-yl derivatives. i. | 1975 | 235267 | |
| [synthesis and pharmacological activity of 1,2,3-triazole derivatives of naphthalene, quinoline and pyridine]. | the preparation of three series of 1,2,3-triazol derivatives, with a naphthalene, quinoline or pyridine ring in 1 position, is described. preliminary pharmacological screening of some of these compounds showed no appreciable activity. | 1979 | 230987 |
| prevalence of nine different micro-organisms in the female genital tract. a comparison between women from a venereal disease clinic and from a health control department. | in a study of the prevalence of nine different micro-organisms in the female genital tract in a swedish population, significantly higher isolation rates occurred among women attending a venereal disease clinic than among those attending a gynaecological health control department. the prevalence of candida albicans, however, was similar in different groups, individual susceptibility being the most important factor. chlamydia trachomatis, trichomonas vaginalis, and mycoplasma hominis occurred conc ... | 1979 | 230884 |
| chemotherapeutically active anthraquinones. i. aminoanthraquinones. | basically substituted 2,6-diacetaminoanthraquinones proved to have an interesting in vivo effect against entameba histolytica, but this effect was markedly exceeded by that of the series of the 2,6-diamidinoanthraquinones. a number of compounds of this series revealed a significantly stronger extraintestinal effect in the golden hamster than the standard amebicides metronidazole and tinidazole, but they were not superior to these compounds in their trichomonacidal effect, which was in general on ... | 1979 | 229867 |
| trichomonas vaginalis resistance to mengo virus infection. | we have investigated the susceptibility of trichomonas vaginalis to mengo virus infection by comparing the outcome of mengo virus or purified mengo virus rna infection in t. vaginalis and in ccl-1 mouse fibroblasts. while the adsorption and entry of mengo virus into t. vaginalis occurred in the same manner as in fibroblasts, the uncoating was much slower. in addition, mengo virus infection of t. vaginalis displayed no eclipse nor any subsequent production of infectious virus. purified rna failed ... | 1979 | 226694 |
| relationship of herpes simplex virus type-2 antibodies and squamous dysplasia to cervical carcinoma in situ. | serum specimens from 75 women with cervical carcinoma in situ, 84 with squamous dysplasia, and 132 controls, who had previously been interviewed and tested for complement fixing antibodies against a number of organisms, were analyzed for hsv-2 antibodies. carcinoma in situ and severe dysplasia were associated with hsv-2 antibodies. mild dysplasia was related to evidence of prior infection by trichomonas vaginalis, adenoviruses, and mycoplasma pneumoniae, plus a history of vaginal discharge. seve ... | 1978 | 215294 |
| genital herpesvirus infection in women attending a venereal diseases clinic. | routine cervical viral cultures (and cultures from lesions if present) were performed on 2630 female patients attending a venereal diseases clinic over a period of four years. of these patients 96 (3.7%) had genital herpetic infection; of these 23 (24%) were asymptomatic. the association of herpesvirus with other genital infections is considered, but no increase in the incidence of neisseria gonorrhoeae, trichomonas vaginalis, and genital warts was found; there was an increased incidence of cand ... | 1978 | 213162 |
| synthesis and biological activity of new 2-nitroimidazole derivatives. | in an earlier paper we described the synthesis and the antitrichomonas activity of 2-nitro-alpha,alpha,1-trimethyl-1h-imidazole-5-methanol (2). starting from this compound, several derivatives have been synthesized. among these, the phenyl carbonate 8 has been shown to possess activity equal to that of 2 and to be less toxic. this compound therefore is interesting in comparison with some antitrichomonas agents currently in use clinically. before undertaking an in-depth investigation, compound 8 ... | 1978 | 211235 |
| post-menopausal vaginitis. | the organisms cultured from the vaginal swabs of 383 women over 50 years old with vaginal discharge were compared with those from 148 normal women of similar age attending a cytology clinic. the only significant difference was that yeasts were found in 20% and 6% of the two groups of women, respectively. it is therefore concluded that in post-menopausal women with vaginal discharge, the main microbiological requirement is for the diagnosis and treatment of yeast infection. | 1978 | 207869 |
| synthesis and biological activity of two metabolites of 1-methyl-5-(1-methylethyl)-2-nitro-1 h-imidazole, an antiprotozoal agent. | 5-(-hydroxyl-1-methylethyl-)-1-methyl-2-nitro-1 h-imidazole (6) and 5-(1,2-dihydroxyl-1-methylethyl)-1-methyl-2-nitro-1 h-imidazole (9) are the principal metabolites found in urines of animals (mice, rats, and dogs) treated with 1-methyl-5-(1-methylethyl)-2-nitro-1 h-imidazole (1), an effective antitrichomonas agent. these two metabolites have been synthesized. compound 6 was found to be less toxic than the parent compound 1 and to possess essentially the same activity against trichomonas vagina ... | 1977 | 199729 |
| [imidazoles in the treatment of infections due to parasitic protozoa "lumenals". (t. vaginalis, giardia intestinalis, e. histolytica--general principles)]. | 1976 | 196967 | |
| 1,4-bis-[1-methyl-5-nitroimidazolyl-(2-methyleneimino)]-piperazine, a new drug with marked activity against entamoeba histolytica. short communication. | 1,4-bis-[1-methyl-5-nitroimidazolyl-(2-methyleneimino)]-piperazine (hoe 316) administered orally produces an effect which is clearly superior to that of metronidazole against entamoeba histolytica in the golden hamster and slightly inferior against trichomonas fetus and t. vaginalis in the mouse. the acute tolerance of the compound is very good (ld 50% greater than 10 g/kg body weight). it is assumed that the possible main metabolite of hoe 316 is a monohydrazone: 1-methyl-2-(4-amino-piperazino- ... | 1977 | 195590 |
| [study of the antiprotozoal activity of compounds of the series of diphenyl ethers and certain nitrostyrols]. | 1976 | 192989 |