Publications

TitleAbstractYear
Filter
PMID(sorted descending)
Filter
effect of carcass size on rate of decomposition and arthropod succession patterns.decomposition studies were conducted using two carcasses of domestic pigs, sus scrofa l., 8.4 kg and 15.1 kg in weight, to determine the effects of carcass size on the rate of decomposition, composition of the arthropod fauna, and succession patterns. a total of 46 arthropod taxa were recovered during this study. no size-related differences were observed between carcasses with respect to composition of the arthropod fauna or patterns of succession. a greater number of arthropods were observed at ...19911750396
[two novel reciprocal translocations involving chromosome 6 in the domestic pig].in the present study 2 new reciprocal translocations are described in two hypoprolific boars. the first one, a gascon/meishan boar, has produced a mean value of 7.37 +/- 0.69 piglets, vs 12.41 +/- 0.22 piglets per litter in contemporaries. the second one, a pietrain/large-white boar, has produced a mean of 5.42 +/- 0.69 vs 12.41 +/- 0.22 piglets per litter in contemporaries. each of these animals carries a new chromosome translocation involving chromosomes 6, 8 and 15, respectively. the first tr ...19911746885
electron microscopical demonstration of thiols and disulphides in the porcine epidermis.this study describes the electron microscopical distribution of free thiols and disulphides in the epidermis of the domestic pig and the wild boar, as compared to light microscopical histochemistry. with the silver methenamine method, silver labelling of thiols was clearly achieved on the keratohyalin and cytofilament accumulations in the cells of the living epidermis and the plasma membrane of granular cells. to a certain extent, the envelope and cytoplasm of young corneocytes reacted equally i ...19911743999
effects of atherogenic diet on young farm pigs.this study was designed to assess the usefulness of young farm pigs as an experimental model for hypercholesterolemia. in order to test this, we investigated both serologic and electrocardiographic effects of atherogenic diet. four-week-old pigs were fed an atherogenic diet for 8 weeks. no arrhythmia was observed on ecg in all animals. there were no significant difference between control and atherogenic diet group on the values of ecg parameters. however, plasma lipids values of atherogenic diet ...19921740169
effects of high arterial oxygen tension on function, blood flow distribution, and metabolism in ischemic myocardium.although oxygen inhalation therapy has long been used in the treatment of acute myocardial ischemia, experimental evidence that increased arterial po2 has any beneficial effect in the absence of hypoxemia is equivocal. in this study, we used a swine model of subendocardial myocardial ischemia to determine the effects of arterial hyperoxia on regional myocardial contractile function (sonomicrometry), myocardial blood flow distribution (microspheres), and regional myocardial glycolytic metabolism ...19921735173
localization of calmodulin in epidermis and skin glands: a comparative immunohistological investigation in different vertebrate species.the study deals with the immunolocalization of calmodulin-reactive epithelial cells in different vertebrates (tinca tinca, ambystoma mexicanum, xenopus laevis, rana ridibunda, columba domestica, sus scrofa domestica, homo sapiens sapiens). the immunoperoxidase technique was performed on acetone fixed frozen sections using monoclonal (bf8) and polyclonal (acam) anti-calmodulin antibodies. we were able to differentiate 2 major types of staining patterns: 1. a more superficial epidermal staining in ...19911718122
[homology between the lpm system of allotypes in the american mink and the gp system of allotypes in the domestic pig].the 5 alpha-macroglobulin allotypes alpha m1, alpha m2, alpha m3, alpha m4 and alpha m5 were identified in pig. the alpha m1 allotype was reported as a marker of pig alpha-macroglobulin, the latter being homologous to alpha 2-macroglobulins in human and in mink. the allotypes alpha m2-alpha m5 were specified as markers of the second isotypical variant of pig alpha-macroglobulins, which was homologous to mink lpm macroglobulin (alpha 1m). as seen from data obtained by international comparative te ...19911714847
distribution of substance p, gnrh, met-enkephalin in the central nervous system of the pig.the distribution of substance p (sp), gonadotropin releasing hormone (gnrh) and met-enkephalin in the brain and spinal cord of the domestic pig is described for the first time. the levels of sp, gnrh and met-enkephalin were measured by specific radioimmunoassays in various regions of the brain and spinal cord of the pig. substance p and met-enkephalin are widely distributed within the central nervous system of the pig. high levels of sp were found in the preoptic area (poa), suprachiasmatic area ...19911714337
histochemical demonstration of zinc in the hippocampal region of the domestic pig: ii. subiculum and hippocampus.the distribution of zinc has been described in two areas of the hippocampal region of the domestic pig, viz., the subiculum and the hippocampus. zinc was demonstrated histochemically according to the neo-timm method, a modification of the sulphide-silver procedure. in each of the examined areas the staining displayed a distinctly stratified pattern which has been compared in detail to fields and layers defined on the basis of cyto- and fibroarchitecture, resulting in a combined chemo- and cytoar ...19911709650
[cytoarchitecture and topography of the ventromedial hypothalamic nuclei of swine (sus scrofa domestica)].the topography and cytoarchitecture of nc. hypothalamicus ventromedialis, nc. hypothalamicus dorsomedialis and nc. infundibularis were descripted in the pig. the nc. hypothalamicus ventromedialis is the dominant nucleus in the tuber cinereum. the rostral pole lies caudal to the nc. hypothalamicus anterior. its caudal pole is bounded by the nc. premamillaris and the nc. hypothalamicus ventrolateralis. scattered neurons separate the nc. hypothalamicus ventromedialis dorsal from the nc. hypothalami ...19901707075
pronounced accumulation of metoprolol in ischemic myocardium after coronary venous retroinfusion.the myocardial availability of the beta 1-selective blocker metoprolol was compared following standard intravenous (i.v.) administration and after coronary venous retroinfusion. thirteen open-chest farm pigs were subjected to 90-min occlusion of the left anterior descending coronary artery. in six of these pigs, metoprolol was administered as an i.v. injection while 7 pigs received the drug retrogradely into the coronary vein. the time of administration was 5 min. in both groups, metoprolol was ...19901688978
protective property of azelastine against histamine challenge of rhinal mucosa in domestic pigs.in anaesthetized domestic pigs a filter paper sampling technique was applied to estimate basal and histamine induced nasal secretion. histamine (0.2 mg/nostril) increased secretion more than twofold, a dose of 2 mg/nostril more than 10 fold. intranasally instilled azelastine (a-5610, cas 58581-89-8) prevented this histamine induced rhinorrhea without reduction of basal secretion. the protective effect remained for more than 2 h even when histamine challenge was repeated.19911686828
human vntr sequences in porcine htf-islands.mapping of complex genomes has been influenced substantially by the isolation of locus-specific, but repetitive dna elements known as vntrs. since a high gc-content is characteristic of most of these elements one might expect them to be clustered at least partially in cpg-islands. to address this question we have constructed a porcine liver dna noti-linkage library in puc18 using isolated htf-islands. hpaii tiny fragments ranging from less than 100 bp to 1 kb in length were randomly selected and ...19911678358
species-dependent differences of high affinity [3h]paf-binding to platelets from humans and pigs and its inhibition by selected antagonists.the sensitivity of blood platelets towards paf (1-o-alkyl-2-o-acetyl-sn-glycero-3-phosphocholine) strongly varies with species and is primarily responsible for different pathophysiological effects after its administration to experimental animals. platelets from domestic pigs were shown to possess one single class of high-affinity paf-binding sites. receptor density and sensitivity of pig platelets towards paf were distinctly higher than those from humans. preincubation of platelets from both spe ...19911662546
monitoring japanese encephalitis virus activity using domestic sentinel pigs in mandya district, karnataka state (india).domestic pigs were used as sentinels in mandya district (karnataka state) in india during 1984 to 1986 to monitor the activity of japanese encephalitis (je) virus in nature. out of 213 sentinel pigs studied in 11 localities, 44 pigs placed at 5 localities showed seroconversion to japanese encephalitis virus. a pig mosquito cycle, operating throughout the year appears to be one of the maintenance mechanisms of the virus in the study area in addition to the bird-mosquito cycle.19911657767
free-running rhythms of adrenocorticotropic hormone (acth), cortisol and melatonin in pigs.in the domestic pig, a circadian rhythm of plasma cortisol occurs, with greatest concentrations in the morning and lowest concentrations in the afternoon. however, photic entrainment of the rhythms of acth and melatonin in pigs have not been defined clearly. this experiment was designed to evaluate free-running rhythms of acth, cortisol and melatonin in pigs housed in constant light (ll) and constant darkness (dd). twelve crossbred barrows, maintained under ambient photoperiod, were catheterized ...19911649029
physical examination of swine.swine may be examined to evaluate a disease state or a lowered economic performance or as a herd health consultation. as much of the examination as possible should be performed without handling the animal. a thorough history, evaluation of herd records, environmental examination, and herd examination should be performed prior to the evaluation of an individual animal. all necessary equipment should be available when starting the individual examination. the animals is then restrained and examined ...19921643555
taxonomic revision of the genus trichinella.the analysis of genetic, biochemical, and biological data on about 300 trichinella isolates, reported in the literature, allows a taxonomic revision of this genus. we propose the recognition of 5 sibling species, trichinella spiralis (owen, 1835) sensu stricto; trichinella nativa britov and boev, 1972; trichinella pseudospiralis garkavi, 1972; trichinella nelsoni britov and boev, 1972 sensu stricto; and trichinella britovi n. sp., on the basis of biochemical and biological characteristics. trich ...19921635024
biological characterization of trichinella isolates from various host species and geographical regions.forty isolates of trichinella collected from 5 continents were compared for 7 biological characters: newborn larvae produced per female worm cultured in vitro at the seventh, eighth, and ninth day postinfection, host muscle nurse cell development time, reproductive capacity index in rats and chickens, and resistance of muscle larvae to freezing. the isolates also were compared by analyses of an environmental character of the location from which they were isolated: the isotherms for january and j ...19921635023
evaluation of an enzyme-linked immunosorbent assay for diagnosis of trichinellosis in swine.experimental and field trials were conducted to evaluate an elisa for its ability to detect trichinella-infected domestic swine and to compare elisa results with muscle-digestion test results. the elisa used was a commercial double-antibody kit, containing an excretory-secretory antigen, and was evaluated principally for epidemiologic use. experimentally induced infection in swine (4 groups of 3 pigs each; inoculated with 0, 50, 500 or 5,000 larvae) was detected as early as postinoculation week ...19921626777
cloning and characterization of highly polymorphic porcine microsatellites.a size-fractionated (200-400 bp) porcine genomic library was screened with the dinucleotide motifs (tg)n and (tc)n. the number of tg- and tc-positive clones was 83 and four, respectively, implying that the former motif is more frequent in the porcine genome, as previously reported in other species. twenty-six tg-clones were sequenced, and the number of repeats varied between 16 and 42 with different compositions of the repetitive sequences; 17 clones had a perfect stretch of tg-repeats, four had ...19921624765
pandemic influenza: a zoonosis?in the last two decades, influenza a viruses have been found to occur throughout the animal kingdom, mainly in birds, notably aquatic ones, in which infection is largely intestinal, waterborne, and asymptomatic. the domestic duck of southern china, raised in countless numbers all year round mainly as an adjunct to rice farming, is the principal host of influenza a viruses. studies based on hong kong h3n2 viruses from southern china suggest that pandemic strains originate from the domestic duck t ...19921609163
occlusion of the pig superior sagittal sinus, bridging and cortical veins: multistep evolution of sinus-vein thrombosis.cerebral sinus-vein thrombosis may lead to severe hemodynamic changes, elevated intracranial pressure (icp), and brain edema. it is supposed that progression of the thrombus from the sinus into bridging and cortical veins plays a key role in the development of these pathophysiological changes, but this hypothesis lacks experimental proof. the aim of this study, using a novel animal model of sinus-vein thrombosis, was to evaluate the effects of a standardized occlusion of the superior sagittal si ...19921607953
helminth parasites of wild boar, sus scrofa, in iran.fifty-seven wild boars (sus scrofa) from protected regions of iran were examined for helminths. sixteen species of helminths were collected; there were ten nematodes, one acanthocephalan, two trematodes and three larval cestodes. new host and distribution records were established for all helminths except of taenia solium cysticerci. wild boar shared nine of these helminths with domestic pigs, six with ruminants and three with human beings in iran. metastrongylus pudendotectus and m. salmi are re ...19921602589
alanine, glutamate, and ammonia exchanges in acutely ischemic swine myocardium.coronary artery disease causes an increase in glutamate uptake and alanine output by the heart. we assessed the effects of acute myocardial ischemia on alanine and glutamate exchange and ammonia production in 10 anesthetized open-chest domestic swine (46.9 +/- 0.7 kg). coronary blood flow was controlled through an extracorporal perfusion circuit. after a nonischemic control period (aerobic) the blood flow in the left anterior descending coronary artery was reduced by 60%. arterial and anterior i ...19921590740
distribution of vasopressin and oxytocin cells and fibres in the hypothalamus of the domestic pig (sus scrofa).the distribution of vasopressin and oxytocin cells and fibres was studied in the pig hypothalamus by means of monoclonal antibodies, in order to prevent the non-specific staining that is characteristic for the pig. the nucleus circularis is described for the first time in the pig hypothalamus and consists of both oxytocin and vasopressin containing cell bodies. a cell group, characteristic for the pig and horse, lateral and caudal from the vascular organ of the lamina terminalis, was found to be ...19921583158
abnormalities in the regulation of blood platelet free cytosolic calcium in malignant hyperthermia. ii. pig platelets.since 1966 the domestic pig has served as the animal model in malignant hyperthermia (mh) research [1]. the use of genetically well-defined pigs rendered it possible to test the method for diagnosing mh-susceptibility of patients presented in the preceding paper. thus, the effect of halothane on intracellular calcium movements was studied in quin-2- and chlorotetracycline-loaded pig platelets. in 'ca(2+)-free' suspensions the resting level of free cytosolic ca2+ was about 60 nm. in contrast to t ...19921576636
experimental human infection with asian taenia saginata metacestodes obtained from naturally infected korean domestic pigs.the infectivity of metacestodes of asian taenia saginata, now tentatively called taenia saginata taiwanensis, in human host was confirmed. the metacestodes used in experimental infection were collected from the livers of naturally infected domestic pigs at an abattoir in cheongju city, korea. the first gravid proglottid was spontaneously discharged 76 days after infection. two worms were recovered two years later by chemotherapy. the scolex was unarmed. the number of main uterine branches, varyi ...19921576110
natural infections of asian taenia saginata metacestodes in the livers of korean domestic pigs.the taenia species in east asia, hitherto identified as taenia saginata, has been recognized as differing from the classical descriptions of life cycles and was recently named taenia saginata taiwanensis (tentatively until 1992). major differences between t. saginata and the newly recognized asian t. saginata are their intermediate hosts and the infected tissues. asian t. saginata metacestodes are found in the livers of pigs rather than in the muscles of cattle. in this study, we observed the na ...19921576109
[is feeding of green silage in areas with hog cholera in wild boar a danger for domestic swine herds? experimental study].in an experimental study we tested the survival of hog cholera virus (hcv) contained in pieces of muscular tissue and organs from experimentally infected swine after incubation in silage. in big (diameter greater than 20 cm) muscular pieces hcv survived even in excellent mineral acid silage (ph 3.8-4.0) after a storage of 5 months. on the other hand in smaller parts (musculature tissue, organs less than 20 cm diameter) we never found virulent hcv after 3 months of incubation. independent of the ...19921575668
[the growth reaction of the temporomandibular cartilage to biomechanical stimuli and its significance for functional orthodontics--the results of experimental animal and biophysical research].adaptive changes in the condylar cartilage of the temporomandibular joint resulting from an experimentally induced lateral occlusal disturbance, were examined in ten juvenile domestic pigs. for the first time, in addition to histological methods for the objectification of changes in the matrix, biophysical methods such as 1h-nmr spectroscopy, electrical impedance spectroscopy and the measurement of mechanically induced potentials were used. changes in the water-binding behavior of the matrix of ...19921551629
[the demonstration of cellular reactions in the temporomandibular condylar cartilage by nmr microscopy. the basic research for high-resolution nmr tomography of the temporomandibular joint].the regional resolution of modern imaging methods is not good enough to clinically objectify changes to the cartilage of the temporomandibular joint, for example in functional orthodontic treatment. nmr microscopic studies of an intact temporomandibular joint preparation were done experimentally in the domestic pig on the basis of 1h-nmr relaxometric measurements in specimens of condylar cartilage. we succeeded in representing the cartilage of the temporomandibular joint down to the cellular lev ...19921551628
[a 2-year study of the incidence of campylobacteriasis in the district of liptovský mikulás].the authors investigated the incidence of campylobacteriosis in the population of the district during 1989-1990. during the above period by cultivation 723 cases of the disease were confirmed, i.e. the incidence in 1989 was 319, the number of cases 428, in 1990 the corresponding figures were 220 and 295. the incidence of campylobacteriosis is significantly higher than that of other investigated bacterial diseases. the authors did not find a significant difference in the incidence of campylobacte ...19921534519
blockade of protein c activation reduces microvascular surgical blood loss.protein c is a natural anticoagulant glycoprotein which prevents intravascular clot formation. protein c functions as an anticoagulant when converted to an active serine protease (activated protein c). activated protein c is formed at the site of the endothelial injury in response to blood clotting and helps limit the size of blood clots. we tested the hypothesis that by temporarily blocking the activation of intrinsic protein c, we could reduce subsequent surgical blood loss from a microvascula ...19921528031
[reconstruction-plasty of iatrogenic choledochal stenoses using human pericardium. an experimental study in the domestic pig].the effect of human pericardial patch plastic for reconstruction of iatrogenic common bile duct stenosis was investigated in experiments performed in pigs. all patches (n = 8) were overgrown with immature biliary epithelium detectable on light and electron microscopy within 6 weeks. no restenosis nor any fistula developed during this observation period. liver function tests, especially bilirubin, were not suitable parameters for the detection of biliary obstruction (preoperative value 0.38 +/- 0 ...19921514292
right heart function during prosthetic left ventricular assistance in a porcine model of congestive heart failure.a left ventricular assist device was used to produce a 90% reduction in peak systolic left ventricular pressure in pigs with congestive heart failure, and the resultant effects on right ventricular function were determined. initially, eight farm pigs underwent rapid ventricular pacing at 230 beats/min for 7 days to produce congestive heart failure. when compared with an independent series of normal pigs, cardiac output in the paced animals was 33.3% less (2.2 +/- 0.2 versus 3.3 +/- 0.5 l/min; p ...19921513147
ex vivo investigation of blood monocyte and platelet behaviour in pigs maintained on an atherogenic diet.domestic pigs aged 4 months were fed for 16 weeks an atherogenic diet rich in cholesterol and saturated fatty acid. the increase of plasma cholesterol and triacylglycerol levels was found to be accompanied by a significant increase in the number of blood monocytes and platelets when compared to control animals. furthermore, the atherogenic diet produced a small but significant reduction in the blood monocyte phagocytic capacity and adhesion to plastic surface. no significant differences between ...19921504579
numerical variation of nucleolar organizer regions after silver staining in domestic and wild suidae (mammalia).selective silver staining was used to investigate the cellular distribution of numbers of nucleolar organizer regions (nors) in domestic pigs (sus scrofa) of eight different breeds, the european wild boar (s. scrofa scrofa), indonesian wild boar (s. scrofa vittatus), javan warty pig (s. verrucosus), sulawesi warty pig (s. celebensis), and pigmy hog (s. salvanius). in the domestic pig as well as in the wild (sub)species of sus, actively transcribing ribosomal rna genes were found to be present in ...19921503258
seasonal abundance of lutzomyia shannoni (diptera: psychodidae) on ossabaw island, georgia.population dynamics of lutzomyia shannoni were monitored from april 1986 through december 1987 on ossabaw island, ga. most (99%) of the 19,788 adult sand flies were collected in light traps supplemented with dry ice; less than or equal to 1% were aspirated from diurnal resting sites. adult sand flies first appeared in april and were followed by peaks of abundance during may 1986, and may and july 1987. numbers of adults captured fell rapidly in october and november 1986 and in september and octo ...19921495026
bite-force development, metabolic and circulatory response to electrical stimulation in the canine and porcine masseter muscles.the development of fatigue was investigated by electrical stimulation in 15 domestic pigs (1 yr old, 70-90 kg body weight) and seven adult dogs (3 yr old, 45 kg body weight). after anaesthesia, silver electrodes were implanted in the anterior and posterior parts of the right masseter muscles. the contralateral muscle was used as control. the bite force was measured. muscle biopsies were obtained from the anterior, central and posterior parts, and were immediately frozen in liquid nitrogen. a flu ...19921471960
does a single bout of exercise cause adaptation of amino acid metabolism in pigs?amino acid responses to exercise stress in well-trained racehorses and human athletes are well characterised, but the knowledge of amino acid metabolism during and after exercise in inactive animal species is limited. to study this, plasma amino acid concentrations were measured in previously unexercised pigs which performed two exercise tests on a treadmill with an interval of one week. in general, the changes in amino acids were more pronounced after the second than after the first exercise bo ...19921465506
intracellular axonemes within ciliated cells in the tracheal epithelium of domestic pigs.extended aggregates of intracellular axonemal derivatives can be seen within the apical cytoplasm of ciliated cells of apparently healthy domestic pigs. such alterations were observed in 15 out of 20 animals. complete (9 + 2) or incomplete (8 + 2 - 5 + 2) intracellular axonemes were found which sometimes arose from mature, irregularly arranged kinetosomes. in addition, bundles of single microtubules and microtubular pairs were found. in previous investigations on the ciliated epithelium of diffe ...19921452480
acute and chronic morphine administration in swine.functional responses to acute and chronic morphine administration in domestic swine were examined and correlated with pharmacokinetic profiles. acute effects of morphine sulfate were monitored in pigs for 24 h and the chronic actions of morphine alkaloid were monitored for 21 days. serum morphine levels, nociception, locomotor activity, respiratory rate, body temperature, and body weight were monitored during all studies. to assess nociception in a large laboratory animal, a portable thermal sti ...19921448475
extracorporeal circulation as an alternative to open-chest cardiac compression for cardiac resuscitation.open-chest direct cardiac compression represents a more potent but highly invasive option for cardiac resuscitation when conventional techniques of closed-chest cardiac resuscitation fail after prolonged cardiac arrest. we postulated that venoarterial extracorporeal circulation might be a more effective intervention with less trauma. in the setting of human cardiac resuscitation, however, controlled studies would be limited by strategic constraints. accordingly, the effectiveness of open-chest c ...19921446500
the transovarial transmission of babesia trautmanni by rhipicephalus simus to domestic pigs.rhipicephalus simus was, for the first time, experimentally proven to be a transovarial vector of babesia trautmanni of domestic pigs. the nymphal and adult progeny of experimentally infected female ticks transmitted the infection to 2 susceptible splenectomized pigs. features of the infection included a prepatent period of 6-8 days post-tick infestation, a febrile reaction for 3 days and a maximum parasitaemia score of 15 (more than 6 parasites per 300 red blood cells). other clinical signs in ...19921437025
percutaneous obliteration of the cystic duct with a holmium:yttrium-aluminum-garnet laser: results of in vitro and animal experiments.the purpose of this study was to investigate the feasibility of using a holmium:yttrium-aluminum-garnet laser to permanently occlude the cystic duct in order to isolate the gallbladder from the biliary-enteric circulation and prevent gallstone formation.19921414812
the gene map of the pig (sus scrofa domestica l.): a review.a review of the present status of the porcine gene map is given with references. a total of 84 loci have now been studied, and genes have been assigned to 17 chromosomes. among them, six chromosomes are defined by only one marker. no loci have been attributed yet to three chromosomes.19921395726
a chromosome 1-specific dna library from the domestic pig (sus scrofa domestica).chromosomes were prepared from lymphocytes of a male domestic pig and flow-sorted on a dual-laser facs. twenty spots were observed, corresponding to the known pig karyotype of 18 pairs of autosomes plus the x and y. dna was isolated from 10,000 copies of the presumed chromosome 1 spot, restricted with sau3a, ligated into the vector pgem4z, and pcr amplified using universal primers; the products were then re-ligated into puc18. after transformation into escherichia coli, 210,000 independent colon ...19921395721
the influence of intensive hyperbaric oxygen therapy on skin flap survival in a swine model.conflicting reports exist regarding the influence of hyperbaric oxygen therapy on random skin flap survival. the present investigation sought to demonstrate enhanced survival of experimental random skin flaps in swine using an intensive and tapering hyperbaric oxygen therapy regimen that would have direct application in human clinical trials. random cutaneous flaps were surgically constructed on 12 domestic pigs. flaps were designed to obtain a predictable length of necrosis. six pigs did not un ...19921389055
effect of intra-abdominal pressure on abdominal wall blood flow.adverse effects of increased intra-abdominal pressure (iap) on cardiac, pulmonary, and renal function have been well described. abdominal wound healing complications seen in the massively injured patient may also be associated with iap. the effects of iap on abdominal wall blood flow, however, have not been documented. this study examines rectus sheath (rs) blood flow in a porcine model of increased iap. seven domestic swine were anesthetized with pentobarbital and maintained with isoflurane. sw ...19921388005
characterization and pathogenicity for pigs of a hog cholera virus strain isolated from wild boars.one hog cholera virus strain isolated from an outbreak of the disease in a wild boar breeding herd in brittany (france) in 1990 has been characterized with a panel of monoclonal antibodies to hog cholera virus and ruminant pestiviruses: the strain was found to be indistinguishable from that of other domestic pig isolates. the pathogenicity of the strain to domestic pigs was evaluated by infecting intranasally, intramuscularly and by contact 17 specific pathogen-free 6-week- and 12-week-old pigs. ...19921387299
intramural methotrexate therapy for the prevention of neointimal thickening after balloon angioplasty.the study was performed to test the hypothesis that high local, intramural concentrations of antineoplastic agents at the site of balloon injury inhibit vascular smooth muscle cell proliferation without systemic toxicity.19921386089
immunosuppressive macrolides of the type fk 506: a novel class of topical agents for treatment of skin diseases?the immunosuppressive macrolide antibiotics fk 506 and rapamycin were tested for topical activity in experimental allergic contact dermatitis of farm pigs. this species was used because pig skin, in comparison to rodent skin, resembles human skin more closely. for comparison, cyclosporine a (cya), which is orally but not topically active in patients with skin disease, dexamethasone, and clobetasol propionate were used. treatment was performed twice, 30 min and 6 h after elicitation of challenge ...19921375617
the gene for dominant white color in the pig is closely linked to alb and pdgrfra on chromosome 8.white is a widespread coat color among domestic pig breeds and is controlled by an autosomal dominant gene i. the segregation of this gene was analyzed in a reference pedigree for gene mapping developed by crossing the european wild pig and a large white domestic breed. the gene for dominant white color was shown to be closely linked to the genes for albumin (alb) and platelet-derived growth factor receptor alpha (pdgfra) on chromosome 8. an unexpected phenotype with patches of colored and white ...19921362182
tyrosine hydroxylase and acetylcholinesterase in the domestic pig mesencephalon: an immunocytochemical and histochemical study.the mesencephalon of the young domestic pig was studied by tyrosine hydroxylase (th) immunocytochemistry and acetylcholinesterase (ache) histochemistry with focus on the substantia nigra (sn), the ventral tegmental area (vta), and related areas. the purpose was to obtain information on the organization of the mesencephalic, th immunoreactive (th-i), and dopaminergic areas of the pig, in order to provide the necessary background for the possible use of the pig as an alternative large animal exper ...19921355778
somatostatin- and neuropeptide y-like immunoreactivity in the dentate area, hippocampus, and subiculum of the domestic pig.with the principal aim of providing baseline observations for future experimental studies, the distribution of somatostatin-like and neuropeptide y-like immunoreactivities is described in the dentate area, hippocampus, and subiculum of the domestic pig (sus scrofa domesticus) and compared with the distribution described in other mammals. intensely stained somatostatin-like immunoreactive nerve cell bodies were present throughout the region, with highest densities in the dentate hilus, stratum ra ...19921355497
ontogenetic changes in porcine adrenocortical adrenocorticotropic hormone receptors.1. binding of [125i]acth(1-38) analog to adrenal receptors was measured in fetal pigs (sus domesticus) at 15-day intervals from midpregnancy (60 days) to near term (105 days; pregnancy length 114 days). 2. binding was greatest at day 60 (0.42 +/- 0.03 fmol/200 micrograms protein or 0.50 +/- 0.08 fmol/50 micrograms dna), and least at day 105 (0.13 +/- 0.03 fmol/200 micrograms protein or 0.16 +/- 0.04 fmol/50 micrograms dna). total adrenal binding was constant (0.61 +/- 0.02 fmol/paired adrenals). ...19921316295
isoenzymatic pattern and structure of glutamate dehydrogenase from ascaris suum.the isoenzymatic pattern of glutamate dehydrogenase (gdh) has been described for ascaris suum a parasite of sus scrofa domestica. only one band of activity has been revealed, suggesting a monomorphic condition for this enzyme. also, the structure of gdh has been assayed by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (sds-page) and silver staining. only one subunit was present with a molecular weight of about 55,000. a hexameric structure for gdh of a. suum is suggested.19921293199
skin tension lines in the domestic pig.the skin tension lines of the domestic pig have been mapped. with a 6mm punch biopsy, local relative skin forces can be determined. the influence of various factors (such as age, fat deposition, gascial attachments, and previous scarring) on the direction of the skin tension lines is discussed.19761273151
experimentally induced steroid atrophy in the domestic pig and man.a histological method of ranking topical steroid preparations according to the degree of epidermal thinning they cause in pig skin has been shown to be applicable to human skin. a 0-05% ointment of the new compound, clobetasone butyrate (molivate), has been shown to cause less thinning than either fluocinolone acetonide 0-025% (synalar) or flurandrenolone 0-0125% (haelan) when applied without the use of occlusive dressings for 3 weeks to the human forearm.19761268070
the effect of clobetasone butyrate and other topical steroids on skin thickness of the domestic pig.a new glucocorticoid, clobetasone butyrate, has been shown in patients to have good topical anti-inflammatory activity and a minimal effect on hypothalamic-pituitary-adrenal function. among a group of topically active corticosteroids, compared in a controlled study in the domestic pig, clobetasone butyrate is shown to cause less epidermal thinning than any of the others except only 1% hydrocortisone. this evidence of a lesser atrophogenic effect may indicate further dissociation of unwanted from ...19761268065
arbovirus infections in sarawak: the role of the domestic pig.the possible role of pigs as arbovirus maintenance hosts and their importance as amplifier hosts was studied. blood samples from 464 pigs of all ages collected in 1962 and 1964 were tested against 10 arboviruses. antibodies to japanese encephalitis and getah viruses were particularly prevalent and their calculated monthly infection rates were 19-5% and 13-3% respectively. in 1969, 447 pigs were bled monthly throughout the year and the infection rates for japanese encephalitis virus were calculat ...19761265821
toxicological studies on azapropazone.the toxicity of azapropazone, a non-steroidal anti-inflammatory analgesic compound was studied in mice, rats, hamsters, guinea pigs, rabbits, cats, mongrel and beagle dogs, domestic pigs, rhesus monkeys, cynomolgus monkeys and baboons in experiments which ranged from acute, single-dose studies up to treatment periods of 1 year. the beagle dog was found to be especially sensitive to gastro-intestinal ulceration from azapropazone and this contrasted with the marked lack of gastro-intestinal hazard ...19761261299
neonatal behavior and nutrition-related mortality in domestic swine. 19761248968
[histometric findings in the adrenals of the domestic pig with reference to constitutional defects].the piétrain pigs are significant different from the german landrace and the edelschwein in the histometrical parameters of the adrenal glands like cortex and medulla part, height of the cortex regions, part of adrenaline and noradrenaline producing cells. the weight of their adrenal glands is less than in the other races but their part of zona fasciculata and of adrenaline producing cells is comparably high. these findings let expect distinct reactions on stressors. there are no hints on insuff ...19751229244
testosterone levels in early fetal testes of domestic pigs. 19751218196
[effect of the type of management and training on heart rate, rectal temperature and respiration rate of domestic swine during physical exertion].29 pigs (meat type of german landrace) were kept in groups in a confined space (0.48 m2 a head; group e), in a normal area (1.2 m2 a head; group n) or in a normal area plus daily exercise (group l). after having been kept under these conditions for specified periods, the pigs were made to run on a band moving at 1.1 metres a second for 2 km. during exercise the heart rate increased to 275 beats a minute in group e and only 180 in group l. in group l the recovery pulse rate was greater and the ab ...19751200748
[lactic acid content of blood plasma in domestic swine of various breeds during physical exertion].lactic acid was determined by an enzymic method in plasma samples taken from 20 pigs of the german edelschwein, german landrace, german saddleback and edelschwein/landrace crosses before, during and after being made to run on a band moving at 1.3 metres/second for ten minutes, at 10 degrees c and relative humidity of 65-75%. a special method was used to assess the degree of exertion. the lactic acid curve showed that edelschwein and german saddlebacks had a low regulatory capacity while german l ...19751200746
experimental phomopsis leptostromiformis mycotoxicosis of pigs.the susceptibility of the domestic pig to intoxication by the causative mycotoxin of lupinosis was established experimentally. the symptomatology and pathology of the disease produced by the administration of toxic cultures of the fungus, phomopsis leptostromiformis (kühn) bubák ex lind to pigs are described. the toxin induced severe loss of weight and, in many cases, posterior paresis or paralysis. the principal gross lesions were generalised icterus, orange-red discoloration of the liver, neph ...19751195271
14c-glucose and 35s-metabolism of pig epiphysial cartilage and its variations after osteotomy.on in vitro incubation of articular and epiphysial cartilage of the ulna of the domestic pig 70 to 80 per cent of [u-14c] glucose was metabolised to 14c-lactate, but cartilage of the epiphysial plate produced up to five times as much 14c-co2 as articular cartilage, and the specific radioactivity of 14c(or 35s)-chondroitin 4(6)-sulphate isolated from epiphysial cartilage (following 35s-sulphate incorporation) was about twice as high as that of articular cartilage. six weeks after an osteotomy on ...19751194320
physiological aspects of sperm transport in the domestic pig, sus scrofa. i. semen deposition and cell transport. 19751192167
[evaluation of blood glucose concentration during exertion. 6. effect of anemia on the glucose regulation capacity of domestic swine in standardized running exercise].individual mean blood glucose values and the scatter of individual values were determined in six healthy and six anaemic pigs before, during and after ten minutes of exercise on a belt moving at 78 m/min (environmental temperature 22-24 degrees c, relative humidity 55-65%). the glucose regulatory capacity of anaemic pigs was inferior to that of healthy pigs. blood glucose regulation was related to haemoglobin content and to the increase in rectal temperature during exercise.19751190980
[effect of anemia on various reactions of domestic swine due to physical exertion. 4. changes of serum acid-base equilibrium].carbon dioxide tension, ph and the excess of base were determined in blood samples obtained from the posterior vena cava of six healthy and six anaemic pigs subjected to ten minutes of exercise on a belt moving at 78 m/min at 22-24 degrees c and relative humidity of 55-65%. the fall in these values during physical exertion was greater in anaemic than in healthy pigs. the roles of buffering capacity and rise in body temperature, and the relationship between blood lactic acid and base excess were ...19751190977
[effect of anemia on various reactions of the domestic swine due to physical exertion. 3. changes in plasma glucose and lactic acid concentrations].six anaemic and six healthy pigs were exercised for ten minutes on a belt moving at 78 m/min. initial blood glucose values in healthy pigs averaged 71.2 mg/100 ml, and they changed very little during and after exercise. initial values were similar in anaemic pigs (70.7 mg/100 ml), but they increased continuously, during exercise, reaching a peak of 157.4 mg/100 ml one minute after the end of exercise. blood lactic acid increased from 1152 to 2463 mmol/litre in healthy pigs during the first minut ...19751190976
[effect of anemia on various reactions of the domestic swine due to physical exertion. 2. components of cardiovascular function and body temperature].the following measurements were made in six anaemic and six healthy pigs during and after physical exertion on a belt moving at 70 m/min for 10 minutes at environmental temperature of 22-24 degrees c and relative humidity of 55-65%:--rectal temperature (rt), heart rate, total haemoglobin, plasma volume (pv), blood volume (bv) and plasma osmolarity (po). the increase: in rt and po, heart rate during exercise, respiratory rate after exercise, and the fall in pv and bv during exercise as well as ch ...19751190975
[effect of anemia on various reactions of the domestic swine due to physical exertion. i. initial values and characteristics of anemia].in six anaemic and six healthy pigs at rest the following values were determined:--rectal temperature, heart rate, respiratory rate, haemoglobin (hb), haematocrit (hk), total haemoglobin (thb), plasma volume, blood volume, plasma osmolarity, lactic acid and glucose content of plasma, blood ph, carbon dioxide tension and base excess. there were significant differences between anaemic and normal pigs in hb, thb, relative thb, hk, mean cell haemoglobin concentration, lactic acid content; in the ecg ...19751190974
modification of ventricular fibrillation latency following coronary artery occlusion in the conscious pig.abrupt occlusion of the left anterior descending coronary artery was performed on 45 unanesthetized farm pigs in order to evaluate the relative effects on the latency to ventricular fibrillation (vfl) of 1) adaptation of the animals to the laboratory, and 2) beta-receptor blockade by propranolol. compared to control values, vfl was greatly lengthened (i.e., vf delayed or prevented) by adaptation (p smaller than 0.01), was shortened by large (2 mg/kg) doses of racemic propranolol in unadapted ani ...19751167816
mekong schistosomiasis. 4. a parasitological survey of wild rodents, domestic pigs and cattle on khong island, laos.no evidence of infection with the mekong schistosoma was found in 12 rattus exulans, 81 r. r. molliculus, and 10 bandicota savilei caught in the vicinity of and downstream from the schistosomiasis transmission focus on khong island, south laos, and examined by dissection and portal perfusion. likewise, no eggs of the mekong schistosoma were detected in faeces of 15 domestic pigs or 43 domestic cattle examined on khong island both by merthiolate-iodine-formalin concentration and by the hatching t ...19751166350
ontogenesis of monoamine oxidase and catechol-o-methyl transferase in various tissues of domestic swine.activities of monoamine oxidase (mao) and catechol-o-methyl transferase (comt) in liver, kidney, heart, spleen, hindbrain, and adrenal glands were compared in adult dogs, cats, guinea-pigs, rabbits, rats, sheep, and 150-day-old swine. swine had the highest comt activity and dogs or cats, the lowest in most tissues. mao was more tissue and species variable. the ontogenesis of mao or comt was evaluated in the same six tissues of swine from 10 days before birth through 150 days of age. comt and mao ...19751156012
uptake of carbon monoxide in blood of miniture pigs and other mammals.different affinities of blood for co were observed in in vivo and in vitro experiments. hamsters showed the greatest relative affinity (1.0), the corresponding value for rats was 0.8, for pigs 0.74 and for rabbits 0.58. the upward shift of the saturation curves was dependent on the rate of respiratory exchange per unit of body weight, e.g. the curves were less steep for pigs than for rabbits. after increased motor activity the equilibrium saturation of co in blood is reached more rapidly. from t ...19751124540
kinetic studies on the erythrocyte hexokinase of the domestic pig, sus scrofa. 19751122722
skin response to x-irradiation in the guinea-pig.skin reaction to x-irradiation has been studied in the albino guinea-pig; early response in limited-field irradiations of the flank is comparable to that commonly seen in rodents, swine and man, and is dose-dependent with a dynamic range from mild erythema to moist desquamation. the peak early skin reaction is seen between 14 and 21 days after irradiation, and declines before 30 days except at the highest doses used. fractionation of the x-ray dose at 24 hours results in a 'sparing' of about 340 ...19761087293
development of the adenohypophysis in the embryo of the domestic pig. 19751080726
studies on development of the adenohypophysis in the domestic pig. 19751080723
vascular supply of the lungs through direct branches of the aorta in domestic pig. 19751080722
extrapulmonary course of the bronchial and bronchoesophageal arteries in the domestic pig. 19751079505
fluoride incorporation into developing enamel of permanent teeth in the domestic pig. 19751066105
deciduous tooth chronology in the mandible of the domestic pig.fetuses of known age, collected from 20 days' gestation to term, were used to characterize the chronology of deciduous tooth development within the right mandible of swine. tooth development was first observed at 32 days' embryonic development, with the differentiation of the deciduous third molar. bud stages for the remaining deciduous teeth differentiated within the period of 32 to 38 days of embryonic development. although the initial histological appearance of these teeth covered a short per ...19761064603
distribution of the dental lamina and deciduous tooth development in the mandible of the domestic pig.specimens of known age, weight, and crown-rump length were used to characterize the distribution of the dental lamina and deciduous tooth development in the mandible of the domestic pig.19751054333
[etiology of benign papillary stenoses].in domestic pigs repeated applications of gastrointestinal hormones (pancreozymin, secretin) as well as cholecystectomy lead to histologic transformation of the epithelium in the area of the papilla of vater and to inconstant pressure changes in the common duct.19761031785
[enzyme histochemical studies on the sebaceous glands of the domestic swine]. 1976999027
[in vitro incorporation of (33p)orthophosphate into the erythrocyte membrane phospholipids of newborn and adult domestic pigs].phosphate turnover of erythrocyte membrane phospholipids, judged by [33p] incorporation, was investigated with phosphatidylethanolamine, lecithin, sphingomyelin, phosphatidylserine, phosphatidylinositol, and phosphatidic acid in newborn and adult domestic pigs. a new micromethod is described in detail using between 10(9) to 10(10) cells, both for quantitative determination of phospholipids and tracer incorporation studies in erythrocyte membrane phospholipids. erythrocyte phospholipid values are ...1976998113
a transferrin variant tf i in crosses of the wild and domestic pigs.in crosses of the wild pig (sus scrofa attila thomas) with the domestic pig a transferrin variant, tf i, was detected, electrophoretic mobility of which was slightly faster than the mobility of the variant tf a. from the results of starch gel electrophoresis, isolation, neuraminidase treatment, autoradiography, and genetic analysis of several families, it can be concluded that the tf i variant is genetically controlled by the allele tf1. thus the number of alleles in the transferrin system of th ...1976970675
the distribution of enzymes in the skin of the domestic pig.on the basis of enzyme histochemical methods, the distribution and the activities of various enzymes in the skin of the domestic pig were investigated. the results are discussed in connection with the importance of the domestic pig as an experimental animal for dermatological research.1976966695
biphasic myelination and the fatty acid composition of cerebrosides and cholesterol esters in the developing central nervous system of the domestic pig. 1976965978
ontogenesis of enzyme systems deaminating different monoamines.1 a detailed investigation into the postnatal development of the activity of the enzyme monoamine oxidase (mao) in the rat and domestic pig was carried out. 2 mao activity was measured in littermate male rats aged between 3 and 122 days belonging to six breeding colonies. the tissues studied were three brain regions in which monoamines may play a role in neuronal transmission (septum, hypothalamus, corpus striatum) and, for comparison, in the cerebellum. liver, heart and adrenal glands were the ...1976938797
translocation heterozygosity in a malformed piglet and its normal littermates.a translocation with centric fusion between the nos. 13 and 17 acrocentric chromosomes was described in a malformed female piglet and three phenotypically normal littermates by the g-banding staining technique. since the translocation was heterozygous, the chromosome number was 37. the differences between the translocation of the present cases and those previously reported in the domestic swine species, as well as in some wild pigs, are mentioned.1977929432
percutaneous cardiac puncture in domestic pigs.blood sampling by percutaneous cardiac puncture was carried out in 69 domestic pigs. the procedure was shown to be safe and to produce reproducible data. the technique can be carried out without anaesthesia. repeated sampling is possible over minutes, hours or days, and a wide range of sample volumes can be achieved by this technique.1977921641
[reactions of european wild boars (sus scrofa scrofa l.) to running stress. 1. behavior of respiratory and heart rate as well as the rectal temperature in standard tests of varying intensity and duration].eight wild boars, aged between twelve and six months and weighing between 81 kg and 39 kg, all kept on floor surfaces and diets used also for domestic pigs, were exposed on a horizontally operated belt to three locomotor stresses which differed by intensity and duration. the speeds were 78 m/min in tests a and c and 138 m/min in test b. the time was limited to ten minutes in test a and 40 minutes in test c, whereas in test b the animals were kept running their rectal temperature had gone up to 4 ...1977921480
[spatial arrangement of chromosomes in somatic cell nuclei. iv. homologous chromosomes in guinea pigs and domestic pigs].space location of chromosomes in metaphasic cells was investigated using brains of 30 cavia cobaya and 30 sus scrofa, in norm and under x-ray treatment (500 r) and dipin action. conjugation of homologous chromosomes under normal conditions was determined, with a high rate reliability, to be equal to the 0.99 level of measuring, within the limits of the elaborated mathematical model. high rate of translocations of homologous chromosomes were discovered in animals subjected to the above mutagen tr ...1977919031
Displaying items 4501 - 4600 of 4678