Publications

[effect of sodium selenite on the course of acute experimental myocardial infarct].	the effect of sodium selenite on experimental myocardial infarction was investigated in 47 domestic pigs, with a major emphasis on the hemodynamic antiarrhythmic effects of selenium. intravenous sodium selenite administered in a dose of 1-2 mg/kg body weight produced a favorable pharmacologic effect. the hemodynamic action consisted in an increase of heart rate, and the maximum aortic flow rate, cardiac output, minute volume of the heart and coronary flow, as well as a decrease in total peripher ...	1985	4079230
a four-year survey of african swine fever in malawi.	a serological survey of free-ranging domestic pigs in the central and southern regions of malawi, together with laboratory data on confirmed cases of african swine fever (asf) and data from interviews with pig owners, undertaken over a four-year period from 1981-4, has enabled the asf enzootic area of malawi to be identified. the area covers much of the western part of the central region and includes mchinji district and parts of kasungu, ntchisi, dowa and lilongwe districts. mortality is substa ...	1985	4067292
reperfusion before global ischemic arrest improves the salvage of infarcting myocardium.	to study the effect of hypothermic global ischemic arrest on an evolving myocardial infarction and of perfusion of the ischemic zone or region at risk before global ischemia, 62 farm pigs underwent 15, 30, or 60 minutes of reversible coronary occlusion. twenty-eight of these animals served as controls: reflow to the region at risk was established by removal of the coronary occluder without the addition of global ischemia. another 26 animals had similar periods of coronary occlusion and then were ...	1985	4062403
effects of different-shaped tissue expanders on transluminal pressure, oxygen tension, histopathologic changes, and skin expansion in pigs.	this study, performed on domestic pigs, was designed to show whether the shape and size of a tissue expander influences the amount of surface area increase. when a defect is irregular, a larger custom-fitted implant is more efficient than several smaller expanders. oval implants gained 5 percent more skin using 50 percent less time and almost 20 percent less intraluminal pressure, while u-shaped implants yield 2.2 percent more skin in 10 percent less time with 35 to 50 percent less pressure when ...	1985	4059413
topical chemotherapy of intradermal walker 256 carcinosarcoma with diaziquone and doxorubicin in the rat.	a model for metastatic skin cancer using intradermal injection of walker 256 carcinosarcoma has been developed in the rat. using this model, antitumor activity of topically applied doxorubicin and diaziquone in vanicream, plastibase, and dimethyl sulfoxide (dmso) as vehicles was compared with intraperitoneal injection of the drugs at the same doses beginning 4 days after injection of tumor cells. doxorubicin applied topically at 0.5 mg/day for 4 days in vanicream or plastibase exhibited no antit ...	1985	4053022
assignment of the porcine major histocompatibility complex to chromosome 7 by in situ hybridization.	the major histocompatibility complex (sla) of the domestic pig (sus scrofa) was regionally mapped to 7p12----q12 by in situ hybridization with an sla class i-specific recombinant dna probe. this localization contradicts linkage data suggesting a possible assignment of the sla locus to porcine chromosome 15.	1985	4042688
peripheral plasma prolactin concentrations during oestrous cycles in different types of primitive gilt.	plasma prolactin concentrations were determined by radioimmunoassay during oestrous cycles and around the time of oestrus in different types of primitive gilts: vietnamese, zlotnicka and wild-boar x domestic pig hybrids. the animals were bled without stress from an indwelling arterial catheter. the following results were obtained: (1) in all gilts the main prolactin peak was observed at day 15 or 16 of the oestrous cycle; (2) vietnamese and hybrid gilts showed a second smaller prolactin surge af ...	1985	4038515
histologic and temperature alterations induced by skin refrigerants.	the histologic alterations induced by spray refrigerants independent of and in combination with dermabrasion were studied with the use of the domestic pig as a model. tissue injury was found to be a function of spray duration and freeze intensity. both preabrasion freezing and postabrasion refreezing could produce damage additive to that of mechanical planing. skin surface and intradermal temperature variations during refrigeration were recorded. the possible implications of these findings as th ...	1985	4008684
comparison of lung antioxidant levels in humans and laboratory animals.	basal lung concentrations of ascorbic acid (aa), nonprotein sulfhydryls (npsh), and alpha-tocopherol (alpha-t) were determined in rabbits, guinea pigs, rats, hamsters, mice, domestic pigs and sheep, and in human lung samples obtained from cancer surgery patients. significant differences were found among the laboratory animals: aa levels ranged from 25.6 mg% (mg/100 g wet weight) in hamsters to 41.7 mg% in mice, npsh from 50.9 mg% in rats to 84.7 mg% in rabbits, and alpha-t from 1.01 mg% in hamst ...	1985	4003918
trichinella spiralis: acquired immunity in swine.	the ability of domestic pigs to develop protective immunity to trichinella spiralis in response to inoculation with different doses of muscle larvae was assessed. adult worms developing from the inoculations of 112, 500, and 10,000 larvae were expelled from the intestine about 6 weeks after inoculation. inoculation with 25,000 larvae, however, resulted in more rapid intestinal worms expulsion, indicating that gut expulsion is dose dependent. secondary expulsion also tended to be dependent upon p ...	1985	3996525
group r streptococci: wild boars as a second reservoir.	group r streptococci have caused many cases of septicaemia and meningitis in patients handling live or slaughtered pigs which were the only known reservoir of group r streptococci. a human case, due to a wild boar, is reported here and it is therefore concluded that there exist both a domestic (pig) and a wild (wild boar) reservoir of group r streptococci.	1985	3992197
notes on placentation in the suina.	we examined the gross and microscopic anatomy of placental tissues and umbilical cords from six species representing the three living families of the suina. these species included, of the suidae, the wart hog (phacochoerus aethiopicus), the giant forest hog (hylochoerus meinertzhageni), the domestic pig (sus scrofa), and the banded pig of malaysia (sus scrofa vittatus); of the tayassuidae, the white-lipped peccary (tayassu pecari); of the hippopotamidae, the hippopotamus (hippopotamus amphibius) ...	1985	3991477
effects of calcium entry blockers on coronary constriction and myocardial ischemia due to leukotriene d4.	recent studies show that leukotrienes (lts) produce profound coronary artery constriction. although calcium entry blockers are commonly used to remedy coronary vasospasm, their capacity to interfere with lt-mediated coronary constriction is unknown. therefore, we compared effects of intracoronary ltd4 before and during treatment with calcium entry blockers in the in situ, blood-perfused hearts of domestic pigs. intravenous administration of verapamil (0.1-1.6 mg/kg), nifedipine (10 or 100 microg ...	1985	3981457
regeneration of epidermis by cells grown in tissue culture.	pig epidermal cells were grown in vitro for 21 to 180 days, forming multilayered sheets of epidermis varying from thirteen to forty layers. for an evaluation of their use in wound coverage, they were transplanted onto surgically prepared full-thickness wound beds on domestic swine. autologous epidermal cells were studied on twenty-five of the animals, and allogeneic epidermal cells were studied on thirteen. autologous epidermal cells grown in vitro provided functional wound coverage 10 to 15 day ...	1985	3973141
comparison of experimental hypercholesterolemia and atherosclerosis in göttingen mini-pigs and swedish domestic swine.	mini-pigs of the göttingen strain and domestic swine of the swedish landrace were compared with respect to their susceptibility to alimentary hypercholesterolemia and experimental atherosclerosis. hypercholesterolemia was produced in both strains by adding 11.2% egg yolk and 0.5% cholesterol to the diet. the plasma cholesterol rose significantly faster and reached a higher level in the mini-pigs than in the domestic swine. in both strains most of the elevated plasma cholesterol was found in the ...	1986	3964345
chromosome mapping in domestic pigs (sus scrofa): pk is not linked to the syntenic group mpi-np on chromosome no. 7.		1985	3930427
chromosome mapping in domestic pigs (sus scrofa): mpi and np located to chromosome 7.		1985	3930426
measurement by electrical impedance aggregometry of porcine platelets response to selected physiological agonists.	although the domestic swine is commonly employed for physiological studies of the coronary circulation, there is relatively little data available concerning the responsiveness in whole blood of normal porcine platelets to standard physiological agonists. such information is essential if the domestic swine is to be used as an animal model for studying potential interactions between platelets and the coronary circulation. accordingly, the present study was undertaken to characterize the responses ...	1985	3923491
[in vitro oxidation of [u-14c] palmitate, [1-14c] and [6-14c] glucose in newborn and adult rats and pigs].	studies have been made on the intensity of oxidation of [u-14c]-palmitate, [1-14c]- and [6-14c]-glucose by slices of the liver and skeletal muscles of new-born, 1-day, 5-day and adult wistar rats and domestic pigs. it was found that the level of 14co2 production from these substrates is higher in tissues of rats than in those of pigs. at early stages of ontogenesis, in tissues of both species intensive oxidation of glucose is observed together with oxidation of fatty acids. in the course of onto ...	1985	3920843
the epidemiology of african swine fever: the role of free-living hosts in africa.	the known distribution of african swine fever (asf) virus in africa is reviewed in relation to the distributions of its free-living hosts as are the infection rates of these species in different localities in southern africa. mechanisms by which asf virus is maintained in its sylvatic state and ways in which the infection may enter domestic pig populations are discussed.	1985	3911134
influence of light and photoperiodicity on pig prolificacy.	in the wild pig mating activity is seasonal. the main breeding period is in late autumn but a second period may occur around april. it is known from other species that seasonal variations in breeding activity are mainly regulated by photoperiod. in the domestic pig seasonal influences on prolificacy still exist: for example, ai boars not only show decreased steroid synthesis, sperm counts and libido in summer compared with the optima which occur in winter but also a biphasic pattern with a trans ...	1985	3910824
[animal experiment studies on the healing of bone transplants by clamping plate fixation following hyperthermic denaturation].	the re-use of resident bone transplants after hyperthermic denaturalization is demonstrated in radiologically, clinically, and histologically in the lower jaw of the domestic pig. periosteal and enosteal osteogenic effect is induced.	1985	3909673
nucleoside transport and metabolism in erythrocytes from the yucatan miniature pig. evidence that inosine functions as an in vivo energy substrate.	erythrocytes from the yucatan miniature pig, like those from the normal domestic pig, lack functional glucose transporters and were unable to utilize plasma glucose as an energy source. in contrast, inosine and adenosine entered the cells rapidly. the nucleoside transporter responsible for this uptake was identified as a band 4.5 polypeptide (5000 copies per cell; apparent mr 45 000-66 000). inosine concentrations in the physiological plasma range (1.6-2.5 microm) were found to maintain normal e ...	1985	3902093
lipid transport systems: some recent aspects in swine, cattle and trout during development.	lipids such as triacylglycerols, free and esterified cholesterol and phospholipids are essentially insoluble in water; lipoproteins, which are complex macromolecules of pseudomicellar structure, have evolved to ensure their efficient transport in the vascular system of vertebrates. plasma lipoproteins are operationally classified according to their relative lipid and protein contents and thus according to density. the protein components, i.e. apolipoproteins, have a highly specialized structure ...	1985	3887526
[genetic and functional effects on fiber type composition and fiber diameters in the longissimus muscle of the thorax and the semitendinous muscle of swine. studies of exercised domestic swine and wild swine kept under restricted mobility].		1985	3886351
pharmacokinetics of chronic fluoride ingestion in growing pigs.	the present study was undertaken to estimate bio-availability and biological half-life of fluoride and accumulation of fluoride in bone in the domestic pig. eight animals receiving 2 mg f-/kg b.w. per day from age 8 to 14 months were compared with eight controls. plasma fluoride concentrations just prior to the daily oral dose were measured at regular intervals. after 112 days post-dose, plasma fluoride levels were measured over a 48-hour period following the daily oral dose or a single intraven ...	1985	3855893
ultrastructure and topography of dense bodies in pinealocytes of castrated males of domestic pig.		1985	3836180
a computer model of hemorrhagic shock in domestic swine.	we used a modified version of the computer model of the circulation developed by c.v. greenway (pharmacol rev 33:213-251, 1982) to study the volume-pressure relationship of the systemic venous circulation during and immediately after massive blood loss. our theoretical predictions were based on experimental measurements performed in conscious, chronically instrumented swine subjected to massive and rapid loss of a predetermined amount of blood. these animals were subjected to an exponential remo ...	1987	3829330
electrophoretic polymorphism of erythrocyte leucine aminopeptidase in the wild boar, sus scrofa.	an erythrocyte leucine aminopeptidase (rbc lap) electrophoretic polymorphism was detected in italian wild boars, sus scrofa. such a polymorphism has not previously been reported in the domestic pig. it is suggested that this locus could be a marker for genetic differences between the domestic and the wild forms of sus scrofa.	1986	3826759
tendons: high-field-strength, surface coil mr imaging.	high-resolution magnetic resonance (mr) images of the tendons of the hands, wrists, feet, and ankles of six healthy volunteers and six cadavers were obtained using receive-only surface coils and reduced-field-of-view imaging. normal anatomy was identified and compared with gross anatomic sections of the six cadavers. experimentally produced tears of the calcaneal (achilles) tendon in domestic swine were identified on mr images. the hands and feet of 11 patients were examined, and a variety of pa ...	1987	3809487
storage of pathogenic leptospires in liquid nitrogen.	the virulence and viability of various serovars of leptospira interrogans were successfully preserved by storage in liquid nitrogen. dimethyl sulphoxide at a final concentration of 2.5% (v/v) was added as cryoprotectant to a culture of leptospires grown in ellinghausen-mccullough-johnson-harris medium. ampoules were cooled at a controlled rate of 1 degree-3 degrees c/min to -70 degrees c, then transferred to the liquid phase of a liquid nitrogen storage unit. glycerol was discounted as a cryopro ...	1986	3804861
intraosseous diazepam suppression of pentylenetetrazol-induced epileptogenic activity in pigs.	intravenous access for the administration of antiepileptic drugs can be both time-consuming and difficult in an actively seizing infant. we conducted a study to examine the intraosseous route as an alternate means of vascular access for the administration of diazepam in a pentylenetetrazol-seizure model in pigs. epileptogenic activity was induced with pentylenetetrazol 100 mg/kg in 15 domestic swine that had undergone craniotomies for electrocortical recording. diazepam (0.1 mg/kg) was administe ...	1987	3800088
[epidemiologic survey of the cysticercosis endemic on réunion island].	the high incidence of cysticercosis was underestimated in reunion island before computed tomography (january, 1984). in 1974, soulayrolles et boyer-vidal found that cysticercosis was responsible for 0.5 p. 100 of the cases of epilepsy. in hospitalized people, routine cranial and muscles radiographies detected: 1/among 242 epileptics: 183 men: 36 positive (19.67 p. 100); 59 women: 9 positive (15.25 p. 100), 2/among 166 non epileptic-related neurological disorders: 106 men, 6 positive (5.66 p. 100 ...	1986	3797934
experimental intrahepatic portacaval anastomosis: use of expandable gianturco stents.	original gianturco expandable stents and their modifications were used to create an experimental intrahepatic portacaval anastomosis (eipca) in 30 young domestic swine without portal hypertension. the study focused on the design of a suitable stent, the technique of its application, and the evaluation of short-term patency of the eipca. a stent with a 2.5-cm-long body and wire skirts on both ends was most suitable for eipca creation. well-positioned stents shunted most of the portal blood in the ...	1987	3797662
pig beta-lactoglobulin i (sus scrofa domestica, artiodactyla). the primary structure of the major component.	beta-lactoglobulins from pooled milk (sus scrofa domestica) are isolated and characterized. the complete primary structure of the major beta-lactoglobulin component i is presented. the amino-acid sequence was elucidated by automated edman degradation of tryptic peptides and cyanogen bromide cleavage products in a liquid phase sequencer. the tryptic and cyanogen bromide peptides were separated by reverse-phase (rp-2) or size exclusion (tsk 2000 sw) high performance liquid chromatography. pig beta ...	1986	3790256
role of adenosine in mediating myocardial blood flow response to isoproterenol: observations in closed chest, sedated, domestic swine.	to test the hypothesis that adenosine is required to mediate the sustained increase in myocardial flow evoked by isoproterenol haemodynamic indices, myocardial blood flow (microspheres), and regional myocardial oxygen consumption were measured in eight closed chest, sedated pigs at control, after isoproterenol (6.9(2.8) ng x kg-1 x min-1 (mean (sd)) infused into the left anterior descending coronary artery, repeat control, and after a simultaneous infusion of the same dose of isoproterenol and a ...	1986	3779747
serum biochemistry of healthy yucatan miniature pigs.	sera collected from 24 (12 boars and 12 gilts) healthy, fasted 28-43 week-old yucatan miniature pigs were analyzed for 21 clinical chemistry parameters. the mean, standard deviation, median, and observed range for each parameter are presented as reference values for the normal blood chemistry for this breed. comparison with published values reveals that the yucatan miniature pig has a blood chemistry profile comparable to that of domestic pigs and other breeds of miniature swine.	1986	3773456
long-acting intramuscular anesthetic regimen for swine.	a two-stage, long-acting, injectable anesthetic regimen which provided pain-free restraint for swine was developed using nine mixed-breed domestic pigs. each animal was administered a first-stage drug combination consisting of meperidine hydrochloride and azaperone in the caudal thigh muscles, followed after 20 minutes by a second-stage group of injections consisting of ketamine hydrochloride combined with morphine sulfate in the same muscles of the opposite leg. a mean surgical anesthetic time ...	1986	3773452
the pig as a model for myocardial ischemia and exercise.	the pig has been well characterized as an appropriate model for the study of coronary physiology, the coronary collateral circulation and exercise physiology. we compared both yucatan miniature swine and young farm pigs in experiments involving myocardial ischemia, infarction and exercise. the yucatan pig was vigorous, docile and proved to be an appropriate model of coronary physiology and exercise in man. the exercise capacity of the yucatan pig was greater than that of the similar weight hamps ...	1986	3773444
effect of a reduction in blood viscosity on maximal myocardial oxygen delivery distal to a moderate coronary stenosis.	this study tested the hypothesis that a reduction in blood viscosity by means of isovolumetric hemodilution will permit an increase in maximal oxygen delivery to myocardium distal to a moderate coronary arterial stenosis. it is known that blood viscosity is a determinant of resistance to blood flow at both the stenotic and the arteriolar levels. accordingly, a reduction in blood viscosity could exert a favorable influence on maximal myocardial oxygen delivery in the setting of stenosis, provided ...	1986	3769166
povidone-iodine in polyethylene oxide hydrogel dressing. effect on multiplication of staphylococcus aureus in partial-thickness wounds.	we studied the ability of a polyethylene oxide hydrogel dressing (vigilon) containing povidone-iodine to prevent staphylococcus aureus proliferation in partial-thickness wounds. we previously reported that a single application of povidone-iodine on wounds challenged with 2 x 10(6) s aureus was not effective in reducing the number of s aureus after 24 hours. it was therefore hypothesized that povidone-iodine might be effective if it was available continuously and applied to wounds containing a sm ...	1986	3767400
the analgesic effect of buprenorphine, etorphine and pethidine in the pig: a randomized double blind cross-over study.	in order to find a suitable analgesic for the treatment of postoperative pain in pigs the analgesic effect of buprenorphine, etorphine and pethidine has been compared in 8 domestic pigs. for assessment of the analgesic action on thermal (hot plate) and two mechanical (cannulation of ear vein, needle prick) noxious stimuli have been employed. in a pilot experiment on 2 pigs in which methadone was included the maximal effective doses were estimated for each drug. methadone was found unsuitable bec ...	1986	3766147
[unsaturated fatty acids in the lipids of the spermatozoa of ovis amon aries l. and sus scrofa domestica l].	spectrophotometric investigations were carried out with five unsaturated fatty acids found in the composition of spermatozoid lipids of animals belonging to four breeds of ovis amon aries l. parallel comparative analysis were made of the fatty acids in the lipids extracted from spermatozoa of landrace swine of the sus scrofa domestica l. species. differences were established as to the percent content of fatty acids, having low points of freezing. it is believed that the criterion of cold resista ...	1986	3765375
polygraphic analysis of the sleep-wake states and the rem sleep periodicity in domesticated pigs (sus scrofa).	electrocorticography and concurrent electromyography were used during a total of nineteen 24 hr periods in three juvenile pigs in order to establish the quantitative duration of the sleep-wake states and the rem sleep cycles. wakefulness (w), drowsiness (dr), slow-wave sleep (sws) and paradoxical sleep (rem) occupied respectively 46.5%, 15.9%, 26.7% and 10.9% of the 24 hr period. mean duration of episodes was 4.1 min for dr, 6.2 min for sws and 3.3 min for rem. sleep cycles (sc) duration was 13. ...	1986	3737741
[individual variability and inheritance of the number and size of the nucleolar organizer regions in chromosomes of domestic swine].	individual variability of the number and size of silver-staining nucleolar organiser regions (nor) was studied in 76 pigs of semirechenskaya, big white and duroc breeds. the variability of the nor number is exclusively caused by the presence of the 8nor- allele (the chromosomes of the 8th homologous pair lacking the silver-staining nor). concentration of the 8nor- allele is about 0.7 in the average for all three breeds. all 7 offsprings from the homozygous parents male 8nor- /8nor- and female 8n ...	1986	3732795
chromosomal localization of leukocyte interferon gene in the pig (sus scrofa domestica l.) by in situ hybridization.	using as a probe pig genomic dna, including the complete interferon alpha gene, we have mapped the leukocyte interferon gene on pig chromosome 1 by in situ hybridization. a total of 196 silver grains were noted on the 106 metaphases scored: 31% of the grains were observed on chromosome 1, and 67% of these were localized in the region 1q2.2----q2.7.	1986	3731881
porcine coccidia in papua new guinea.	faecal samples from 232 domestic pigs raised on concrete, 98 free-ranging village pigs, and five wild boar showed 46.6 (108/232), 54 (53/98) and 80% (4/5) prevalence of coccidian oocysts, respectively. eight species of eimeria, and isospora suis, were recovered. in their descending order of predominance in the pigs raised on concrete, the species of coccidia were e. debliecki (26.7%), e. scabra (22.4%), e. neodebliecki (19.8%), e. porci (15.5%), e. suis (11.6%), e. polita (8.6%), e. perminuta (7 ...	1986	3727342
morphological characteristics of the gyrus dentatus in some animal species and in man.	comparative anatomical investigations have been carried out on the gyrus dentatus of rat, fox, cattle, domestic pig, monkey (cercopithecus sabeus) and man. after removal of the brain stem and scaling off the brain substance from the medial aspect towards the lateral aspect, the gyrus dentatus was preserved and its relation with regard to the hippocampus, the fimbria hippocampi and the gyrus parahippocampalis was studied. a rat's gyrus dentatus occupies a rather wide zone on the medial aspect of ...	1986	3717598
absence of a nocturnal rise in either norepinephrine, n-acetyltransferase, hydroxyindole-o-methyltransferase or melatonin in the pineal gland of the domestic pig kept under natural environment photoperiods.	castrated male and intact female pigs were kept under natural photoperiodic and temperature conditions and were killed over a 24 h period in either may (under long days) or in december (under short days). neither the pineal norepinephrine (ne) concentration nor the melatonin content rose at night; likewise, neither the activities of n-acetyltransferase (nat) nor hydroxyindole-o-methyltransferase (hiomt) increased during darkness. in may pineal melatonin content actually decreased (p less than 0. ...	1987	3696466
hepatic vs. gastrointestinal presystemic extraction of oral midazolam and flurazepam.	an experimental model was developed to elucidate the site of presystemic extraction of drugs with incomplete bioavailability due to high extraction after p.o. dosage. domestic pigs received single i.v. or p.o. doses of midazolam (1 mg/kg) or flurazepam (2 mg/kg), two benzodiazepine derivatives with high presystemic extraction after p.o. dosage. multiple blood samples were simultaneously drawn from the portal vein and from a systemic vein during 8 hr after dosage. after i.v. administration, both ...	1987	3694534
cardiac and coronary consequences of intracoronary platelet activating factor infusion in the domestic pig.	in previous studies we have shown that platelet-activating factor (paf) is a potent vasoactive substance with deleterious effects on coronary blood flow (cbf) and myocardial performance. the present study further investigates the effects of paf during its sustained intracoronary infusion in the blood-perfused domestic pig (n = 16). paf infusion (1-9 nmol/min) produced triphasic changes in cbf (n = 7): an initial brief phase of coronary dilation (14 +/- 2% above baseline), followed by severe redu ...	1987	3685397
study of cathepsin a, b and d activities in the skin wound edges. its application to the differential diagnosis between vital and postmortem wounds.	the aims of the authors in this paper has been to check the diagnostic ability of the cathepsin a, b and d concentrations in the skin wound edges to the differential diagnosis between vital and postmortem wounds. we have studied 56 domestic pigs grouped in seven experimental series consisting of 8 animals in each, according to the time (0, 5, 15, 30 min and 1, 3 and 6 h) after the injury. the enzymatic activities were investigated following the methods by bowen and davison biochem. j., 131 (1973 ...	1987	3679037
role of adenosine in mediating the coronary vasodilative response to acute hypoxia.	to test the hypothesis that adenosine is required to mediate the coronary vasodilative response to acute hypoxia haemodynamic indices, regional myocardial blood flow, and oxygen and lactate metabolism were measured in nine closed chest anaesthetised domestic swine at control, after 3-5 min of 100% nitrogen inhalation, at second control, and after 3-5 min of 100% nitrogen inhalation plus adenosine deaminase infusion in the left anterior descending coronary artery. cardiac lymph adenosine deaminas ...	1987	3664545
trypanosome infections in glossina spp. inhabiting peridomestic agroecosystems in nsukka area, anambra state, nigeria.	trypanosome infections in glossina spp. inhabiting three peridomestic agroecosystems in nsukka area were studied by dissection from april 1984 to july 1985. approximately 0.65% of 4620 g. tachinoides and none of 17 g. palpalis were found with maturing or mature trypanosome infections. of these infections, 20% were due to the trypanosoma brucei group, 40% to the t. congolense group, and 40% to a mixture of the t. brucei and t. congolense groups. trypanosome infection rates did not differ signific ...	1987	3662674
gastrointestinal absorption of americium-241 by orally exposed swine: comparison of experimental results with predictions of metabolic models.	two groups of 11-week-old swine (40 miniature and 40 domestic swine) received a single oral administration of 1.9 x 10(8) bq (5.2 mci) of 241am citrate, and groups of eight animals, four of each type, were killed and sampled at 1, 2, 4, 8, 16, 24, 48, 72, and 96 h and 30 days later. uptake and excretion patterns of the radioactivity appeared to occur in three phases: rapid uptake, rapid excretion, and then a slower excretion. all animals were systematically dissected, and the eviscerated carcass ...	1987	3659299
the occurrence of trypanosoma (nannomonas) simiae in the cerebrospinal fluid of domestic pigs.		1987	3658977
[changes in the content of membrane phospholipids of subcellular structures of skeletal muscle in halothane-induced malignant hyperthermia of the domestic pig].		1987	3651204
failure of foreign serum injections to induce immune vasculitis and to accelerate spontaneous or cholesterol-induced atherosclerosis in swine.	experiments were conducted with domestic swine in an attempt to accelerate and/or modify spontaneous or cholesterol-induced atherosclerosis through immune complex-produced changes in the arterial wall. for the purpose of comparison, another experiment was carried out with rabbits. swine differed completely from rabbits in that various experimental designs failed to produce immune complex arteritis and fibroproliferative arteriosclerosis. in addition, two foreign serum infusions (human plasma and ...	1987	3632754
variations in the monoamine oxidase-inhibitory activity ("tribulin?") in pig's urine.	sandler and his colleagues (see sandler, 1982) have demonstrated the presence of an endogenous inhibitor of the enzyme monoamine oxidase (mao) and of benzodiazepine receptor binding in the urine and blood plasma of man and rat. the concentrations of this material increased under stress conditions and it has been named "tribulin". in the present experiments mao-inhibitory activity was found in extracts of urine and plasma samples of domestic pigs. evidence was obtained that the inhibitory activit ...	1987	3625194
the r-banded karyotype of the domestic pig (sus scrofa domestica l.).		1987	3610655
effects of pentoxifylline on experimental skin flap survival.	we studied the effects of pentoxifylline on experimental skin flap survival in the domestic pig. random skin flaps were designed using a length-width ratio of 5:1. the pigs were then given pentoxifylline (25 mg/kg/d) or placebo for seven days. fluorescein sodium was used to help determine surviving skin flap length seven days postoperatively. results showed no significant difference in mean surviving skin flap length between the study and control groups. we question the value of pentoxifylline i ...	1987	3606845
[structure of the efferent ductules of the domestic pig (sus scrofa domestica)].	the ductuli efferentes of the pig have 2 distinct and continuous segments: the proximal or intratesticular segment that is formed in sequence to the labyrinthic portion of the rete testis, on the cranial extremity of the testis, and the distal or epididymal segment that forms the cani vasculosi or lobuli epididymidis. the testicular ductuli are more thicker and the epididymal ductuli are more thin, long and flexuous. the last segment is very coiled and forms a bulboid structure that is placed in ...	1987	3605639
influence of steroids on hemorrhagic and traumatic shock.	a hemorrhagic-traumatic shock model in 20 domestic pigs (sus scrofa) was used to evaluate the pharmacologic effect of methylprednisolone in preventing disseminated intravascular coagulation (dic). pairs of animals were anesthetized with thiopental and both femoral arteries cannulated. four ml/kg-1 of blood were withdrawn, frozen, thawed, and returned to the animal. one femoral artery cannula was connected to a blood pressure monitor for arterial systolic, diastolic, and mean pressures along with ...	1987	3599114
in vitro normalization of cholesteryl ester content and particle size of fish eye disease high density lipoproteins.	isolated high density lipoprotein (hdl) from the two living fish eye disease patients have been incubated in vitro with autologous lipoprotein depleted plasma or with lipoprotein depleted plasma from domestic pig (sus domesticus), with and without the presence of lcat inhibitor for 24 hours at 0 and 37 degrees c. the lecithin:cholesterol acyltransferase (lcat) activity in lipoprotein depleted pig plasma increased the abnormally low cholesteryl ester content of the fish eye disease hdl particles ...	1987	3591466
biliary and urinary excretion of peptide leukotrienes in the domestic pig.	the metabolism of leukotriene (lt)c4 and its major routes of elimination in vivo have been studied in four anesthetized domestic pigs administered intravenous [3h]-ltc4 (0.5 microci/kg). the kinetic profile of ltc4 in the blood was followed for 60 min after administration while the biliary and urinary excretion of ltc4 and its metabolites were determined over a 120 min interval. the total recovery of radioactivity in bile and urine was 45% +/- 1 (n = 3) and 18% (n = 2) respectively. examination ...	1987	3588975
a reciprocal translocation (7q-;12q+) in the domestic pig.		1987	3583780
articular cartilage blood vessels in swine osteochondrosis.	perfusion studies in swine with early lesions of osteochondrosis demonstrated that lamellar areas of chondrocyte necrosis within reserve zones of growth areas occurred only in regions of nonperfused articular cartilage. articular cartilage with a similar anatomical location was perfused in some animals. occasionally, nonperfused articular cartilage showed vascular alterations within cartilage canals without evidence of significant perivascular or lamellar necrosis. by light microscopy, some vess ...	1987	3576906
a comparison of three geographical isolates of trichinella spiralis from the mid-atlantic united states.	three isolates of trichinella spiralis (black bear: 41o50'n, 79o00'w, 1982; grey fox: 41o00'n, 76o00'w, 1982; domestic pig: 39o80'n, 75o30'w, 1983) from the mid-atlantic united states were characterized in crl: cobs cfw (sw) mice during 10 successive 40-day generations. over 10 generations, the isolates differed as follows: worm position of the ursine isolate was significantly more posteriad compared to the porcine isolate; sex ratio of the vulpine isolate was significantly lower compared to the ...	1987	3572653
trichinella spiralis in an agricultural ecosystem. ii. evidence for natural transmission of trichinella spiralis spiralis from domestic swine to wildlife.	epidemiological investigations of an outbreak of trichinellosis were carried out in a domestic swine herd and it was established that the parasite also occurred in rats, and in skunks, opossums, and raccoons. because considerable uncertainty exists regarding the role of sylvatic trichinellosis as a reservoir for the synanthropic cycle, studies were conducted to determine the genetic nature of the various isolates from this ecosystem. pig infectivity trials, isoenzyme analyses, and repetitive dna ...	1987	3572642
the high resolution r-banded karyotype of the domestic pig, sus scrofa domestica l.	a representative haploid r-banded karyotype of the domestic pig, and a diagrammatic representation of the banding patterns at the 550 band level are presented.	1987	3568755
biochemical events during stapling of the proximal tibial epiphyseal plate in pigs.	epiphyseal stapling is considered a safe, effective method of correcting angular deformities of the knee in growing children. a study of the underlying biochemical events would contribute to a better understanding of the control of longitudinal growth rate in epiphyseal growth plates and of the molecular pathology of exaggerated physiologic bowleg or knock-knee deformities. blount stainless staples were applied to the medial side of the proximal tibia epiphyseal growth plate of domestic pigs. th ...	1987	3568490
evidence for aggression-modulating pheromones in prepuberal pigs.	a series of behavioral bioassays were conducted to determine the aggression-influencing properties of urine and other fluids. subjects were prepuberal castrated male and female domestic pigs from commercial stocks. in the behavior assay, pigs were painted with a test fluid and grouped for a videotaped 90 min observation period. experiment 1 validated use of videotape recording by showing that duration of aggressive behavior registered live was correlated with that obtained from video records (r ...	1987	3566690
"atraumatic" transjugular needle for portal vein puncture in swine.	a new coaxial needle-catheter system was designed for transjugular portal vein puncture in young domestic swine. it was tested in 32 animals and successfully entered the portal circulation via a hepatic vein or intrahepatic portion of the inferior vena cava. no complications were encountered.	1987	3562845
measurement of plasma adenosine concentration: methodological and physiological considerations.	this study tested the hypothesis that measurements of plasma adenosine concentration made on samples of blood obtained in dipyridamole and ehna (i.e., "stopping solution") may be falsely elevated as a result of ongoing in vitro production and accumulation of adenosine during sample processing. studies were performed with samples of anticoagulated blood obtained from anesthesized domestic swine. adenosine concentration of ultra filtrated plasma was determined by high-pressure liquid chromatograph ...	1987	3554257
prostacyclin and thromboxane a2 in septic shock: species differences.	prostacyclin and thromboxane a2 have been implicated as mediators of septic shock. correlations between the human prostanoid response to sepsis and experimental paradigms are poorly understood. the purpose of this study was to compare changes in plasma levels of prostaglandin 6-keto-f1 alpha (pgi) and thromboxane b2 (txb) during septic shock in sprague-dawley rats, domestic pigs, mongrel dogs, and man. severe sepsis followed by septic shock (systolic bp less than 90 mmhg) was induced in rats by ...	1986	3539388
[treatment of sarcoptic mange in wild and domestic swine with ivermectin (ivomec)].		1986	3536415
gross anatomy of the mandibular joint and masticatory muscles in the domestic pig (sus scrofa).	the mandibular joint (mj) and masticatory muscles in 15 domestic pigs, aged 1 year, were investigated during and after dissection. the joint consisted of a fossa, disc and condyle surrounded by a ligamentous capsule. the fossa was almost flat, slightly convex antero-posteriorly and concave medio-laterally; the disc was biconcave and the condyle oval. the long axis of the condyles formed an anteriorly orientated angle to the frontal plane. the masticatory muscles were similar to human ones except ...	1986	3479064
[periodontal diseases in domestic swine].		1986	3467471
[cytoarchitecture and topography of the preoptic area and several selected nuclei of the rostral hypothalamus of the pig (sus scrofa domestica)].		1987	3450096
a complex three breakpoint translocation in the domestic pig.		1987	3447474
[anatomic studies of the pulmonary hypertension syndrome in the domestic pig].		1987	3439630
isolation of japanese encephalitis virus from a sentinel domestic pig from kolar district in karnataka.		1987	3428962
[isolation of a phosphoprotein from preeruptive dentin from molars of domestic pigs (sus scrofa domesticus)].	isolation of a phosphoprotein from dentin of pre-eruptive molars of sus scrofa domesticus. a protein with a relative molecular mass of 60,000 kd was isolated from dentin of unerupted pig molars. the electrophoretically homogeneous protein was identified as phosphoprotein with a specific staining procedure. the phosphorylation degree is 75%. the amino-acid composition and the molecular mass were compared with values of other species.	1987	3426568
intratubular germ cell tumours of pig testicles.	in the course for the histopathological examination of testicles of 30 castrated boars the authors have observed in 4 animals the intratubular growth of atypical germ cells. on the basis of the histological picture this change is equivalent to the human infertile testicles, observed as carcinoma in situ, resp. intratubular germ cell tumour. the described phenomenon occurred in atrophic testicles in 3 of the 4 old animals. the described change in the domestic pig, not known so far, raises the pos ...	1987	3425959
cardiovascular effects of i653 in swine.	i653 (difluoromethyl 1-fluoro 2,2,2-trifluoroethyl ether) is a new inhalation anesthetic with a low blood-gas partition coefficient and no demonstrable toxicity. the authors examined its cardiovascular effects at 0.8, 1.2, and 1.6 mac in eight chronically instrumented domestic swine mechanically ventilated to maintain normocarbia. these data were compared with those obtained while the animals were conscious and while anesthetized with isoflurane at approximately equal mac multiples. i653 caused ...	1988	3415011
metabolic response to prolonged reduction of myocardial blood flow distal to a severe coronary artery stenosis.	limited data are available concerning the effects of mild-to-moderate, sustained reductions of coronary blood flow on myocardial aerobic metabolism. this study tested the hypothesis that a sustained flow reduction distal to a severe coronary artery stenosis may be well tolerated (after the initial insult is passed) because of gradual improvement in the balance between myocardial oxygen supply and demand. studies were performed in eight sedated, closed-chest domestic swine that were instrumented ...	1988	3409507
isolation of african swine fever virus from ticks of the ornithodoros moubata complex (ixodoidea: argasidae) collected within the african swine fever enzootic area of malawi.	ticks of the ornithodoros moubata complex were collected from domestic pig sties and dwelling houses, and from a warthog habitat, and tested for the presence of african swine fever (asf) virus. collections were made in 9 of the 24 districts of malawi, these being primarily the districts in which o. moubata is most numerous. asf virus was isolated from ticks collected in both domestic pig sties and houses in certain villages in mchinji district where asf outbreaks had recently occurred. mchinji d ...	1988	3402546
fatigue of three skeletal muscles in domestic and wild pigs. a comparative study in situ.	the semitendinosus, the gastrocnemius and the soleus muscle were stimulated in situ in young, female domestic pigs (sus scrofa domestica, german landrace) and in european wild pigs (sus scrofa scrofa), by supramaximal impulses via the sciatic nerve. fatigue indices of the whole muscles were registered during a continuous supramaximal stimulation with square wave impulses (0.3 ms) that were given for 10 s with a frequency of 100 hz. in domestic pigs, fatigue indices of all three muscles were sign ...	1988	3399363
comparative anatomy of the foramen ovale in the suina.	the structure of the foramen ovale from six species of suina was studied using the scanning electron microscope. in each species, the foramen ovale, when viewed from the terminal part of the caudal vena cava had the appearance of a short tunnel. in the domestic pig (sus scrofa), the wart hog (phacochoerus aethiopicus) and the bush pig (potamochoerus porcus) a fold of tissue projected from the caudal edge of the foramen ovale into the lumen of the left atrium. it constituted a large proportion of ...	1988	3377202
periodontal disease in feral pigs (sus scrofa) from queensland, australia.	periodontal lesions were present in 26 of 107 feral pigs (sus scrofa) that were shot in southern queensland. the severity of the lesions varied from gingivitis to extensive destruction of the alveolus and its contents. examination of slaughtered domestic pigs revealed a similar prevalence of lesions (12 of 52). only cheek teeth were affected, and molars were affected more frequently than premolars. in both feral and domestic pigs, prevalence of periodontal disease affecting bone increased with a ...	1988	3373625
effect of pressure-controlled intermittent coronary sinus occlusion on pacing-induced myocardial ischemia in domestic swine.	this study tested the hypothesis that pressure-controlled intermittent coronary sinus occlusion (picso) would be useful in ameliorating myocardial ischemia under conditions characterized by preserved, but reduced (relative to demand), myocardial blood flow. studies were conducted in closed-chest, sedated domestic swine prepared with an artificial stenosis that reduced luminal diameter of the animal's left anterior descending coronary artery by 80%. measurements of hemodynamics, regional myocardi ...	1988	3370777
influence of serotonin on myocardial blood flow in the presence and absence of a coronary arterial stenosis: observations in domestic swine.	this study tested the hypothesis that 5-ht may impair coronary flow regulation by inappropriately increasing arteriolar tone in the coronary circulation. ten closed chest, domestic swine were studied both in the presence and in the absence of a severe artificial intraluminal coronary stenosis. a 5-french micromanometer catheter with fluid lumen was placed in the left anterior descending coronary artery and used to record pressure and infuse 5-ht (40 and 100 micrograms/min) into the coronary circ ...	1988	3353390
an animal model for radiologic biliary interventional procedures.	procedural development, in vivo evaluation, and professional training in interventional biliary radiology require an animal model that provides easy and safe access to the gallbladder and bile ducts. a porcine model was used successfully for catheterization of the biliary system under fluoroscopic control. permanent access to the gallbladder of ten pigs was achieved with a large-bore cholecystostomy catheter. catheterization of the common bile duct through the cystic duct was feasible in all ani ...	1988	3338897
[arterial vessels of the kidney in domestic swine].	by histological preparation, measuring, corrosion and angiography were studied the arterial blood vessels of 120 kidneys from 60 individuals at different ages. it was established that the kidney artery in the most cases (70%) divides by the dichotomous type in cranial and caudal or in dorsal and ventral branches, and rarely (30%) by the disseminated type in 3 branches--two cranial and one caudal. investigated were the position, course and branching of the prelobar, interlobar, the arcuate, the i ...	1987	3328404
an updated survey of african swine fever in malawi.	cases of african swine fever (asf) confirmed in the laboratory in 1985 and 1986 and other data obtained since 1984, in particular and extension of the serological survey of free-ranging domestic pigs undertaken from 1981 to 1984, are presented to give an updated survey of the asf situation in malawi and a revised estimate of the asf enzootic area. evidence is presented that the area may include some border areas in dedza and ntcheu districts and may be expanding in some localities.	1987	3322852
dietary mackerel oil in pigs: effect on plasma lipids, cardiac sarcolemmal phospholipids and cardiovascular parameters.	the influence of substitution of eicosapentanoic acid to the diet has been investigated in juvenile domestic pigs (7-8 kg) fed either a mixture of 4.5% (wt/wt) mackerel oil and 4.5% (wt/wt) lard fat (n = 12, ml group) or a 9% (wt/wt) lard fat (n = 12, l group) diet for 16 wk. plasma triglyceride and total cholesterol did not change in l, but had decreased in ml to 51 +/- 8 and 81 +/- 8% of the initial values, respectively, at the end of this period; the largest decreases already occurred during ...	1987	3305815
insulin-like growth factors in the göttinger miniature-pig.	igf i was determined by a radioimmunoassay and igf ii by a radioreceptorassay in 20 göttinger miniature (mini)-pigs and 13 domestic pigs of different weight and age. immunoreactive igf i serum levels of mini-pigs were similar to those of domestic pigs in corresponding age-classes (150-250 and 100-270 micrograms/l, respectively). no differences were detectable between receptor-reactive igf ii serum levels in mini-pigs (150-200 micrograms/l) and domestic pigs (110-270 micrograms/l) nor did the bio ...	1988	3289301
prototheca zopfii: natural, transient, occurrence in pigs and rats.	domestic swine faeces and fresh faeces from trapped barnyard rats were heavily contaminated with prototheca zopfii, a cause of dairy cow mastitis. when the pigs and rats were maintained on prototheca-free diets, the transient intestinal population of p. zopfii decreased precipitously and disappeared. when combined with the information that other farm animals excrete p. zopfii, it was concluded that contaminated animal feed may be the source of large numbers of p. zopfii in the farm environment. ...	1988	3278239
gross anatomy of the craniomandibular joint and masticatory muscles of the dog.	the craniomandibular joint (cmj) and masticatory muscles in 15 dogs (canis familiaris) were dissected. the major structures were fossa, disc and condyle surrounded by a thin fibrous capsule. the horizontally orientated temporal fossa had a pronounced tubercle anteriorly. posteriorly, a retroarticular process curved backwards. this fossa and process closely surrounded the condyle. the disc was thin. the cylindrically-shaped condyle was elongated in the medio-lateral direction, situated at right a ...	1988	3254129
suppression of pentylenetetrazol-elicited seizure activity by intraosseous propranolol in pigs.	the intraosseous (io) route provides a rapid and effective alternative venous access in the pediatric population when the conventional intravenous (iv) route cannot be easily obtained. dl-propranolol, a beta-adrenoceptor antagonist, exhibits antiepileptic activity in various animal seizure models. this study assessed the efficacy of io propranolol in suppressing pentylenetetrazol (ptz)-induced seizure activity in pigs. domestic swine (13-20 kg) were prepared for recordings of arterial blood pres ...	1988	3243927