Publications

morphologic and histochemical characteristics of cell lines derived from hamster peripheral lung tumors.		2003	145368
cardiac hypertrophy and antihypertensive therapy.	biochemical (myocardial dna, rna, and hydroxyproline) and humoral (plasma [pra] and kidney [kra] renin activity) factors were determined in spontaneously hypertensive rats (shr) and normotensive wistar controls (nr) before and following treatment with minoxidil or propranolol. minoxidil (150 mg.litre-1 drinking water) effectively controlled blood pressure (17.3 kpa vs 24.9 kpa [130 mmhg vs 187 mmhg], p less than 0.001) despite marked and sustained increases in both pra and kra ventricular weight ...	1977	145319
a search on karyotypic mosaicism in mongoloid patients and their parents.	the frequency of chromosomal mosaicism among patients with clinical diagnosis of mongolism was determined. among 50 patients with at least 32 cells studied, 2 (or 4%) were found to be mosaics of the 46/47, +g type. among 350 patients with at least 5 cells studied, 2 (or 0.57%) 46/47, +g mosaic cases were detected. taking in account the probability of detecting mosaicism when 5 cells are analysed, a frequency of 0.58% of mosaic cases was estimated for this sample. the mosaic patients were submitt ...	2003	143677
[toxicological characteristics of thaliblastine[].	the toxic action of the antiphlogistic drug thaliblastin, containing 93-95 per cent of the alcaloid thalicarpine was investigated. with its single intraperitoneal injection to mice the dl10 of the drug amounts to 273-306 mg/kg, dl50-325-350 mg/kg and dl90-370-402 mg/kg. with its 5-day long administration the respective figures for mice are 102-165, 125-201 and 154-243 mg/kg and for rats--170, 203 and 272 mg/kg. the respective figures for a 20-day long introduction to mice are 155, 185 and 220 mg ...	1977	143373
acid mucopolysaccharides in metal-induced tumor and connective tissue capsules surrounding implants in rats.		1975	142824
[endolaryngeal nevocarcinoma].		2003	142805
antigen-induced cyclophosphamide-resistant suppressor t cells inhibit the in vitro generation of cytotoxic cells from one-way mixed leukocyte reactions.	mice sensitized against a tumor allograft and given cyclophosmamide 6 days later failed to generate an immune response to the allograft. spleen cells derived from these mice suppressed the generation of cytotoxic t cell response by normal spleen cells in mixed leukocyte cultures. the suppressor cells were not specific, thymus dependent, and resistant to 2000 r.	2003	142792
effect of different albumin media on the lipid-mobilizing action of sympathicotropic substances in vitro.	the authors studied the effect of adrenotropic substances on lipolysis in rat epididymal adipose tissue in albumin medium in vitro. on using albumins of different origin (human, bovine), the pd2 values for catecholamines differed by more than one order, in correlation to the type of albumin used. the isopropylnorsynephrine pd2 values did not differ. the addition of ascorbic acid (100 microng/ml) raised the catecholamine pd2 values and completely equalized the pd2 values found in both media. the ...	1977	140390
[echinococcal cysts of the external oblique muscle. clinical case].	a short account of the nosological, physiopathological and therapeutical aspects of cysts due to muscle echinococcus is given. a case of echinococcus of the external oblique muscle is presented and its diagnostical difficulties pointed out.	2002	140333
problems of classification of low-back pain.		2002	139668
[epidemiological study of shigella dysenteriae 1 in 2 communities of the guanacaste province, costa rica, 1975].		1976	136972
[wolfgang hildebrand's "magia naturalis"].		2002	135379
[disabled children in the federal republic of germany in 1974 (author's transl)].	within the scope of an additional micro-census inquiry--carried out in 1974--the federal statistical office in wiesbaden assessed the number of physically, mentally and psychologically impaired children. the results are differentiated according to the types of disability and therapy, age, in-patient treatment and special school attendance. furthermore, the estimated results are compared with earlier surveys of the federal statistical office and other estimates.	2002	135318
[vitelliform degeneration of the macula].	macular vitelliform degeneration is an hereditary affection, with autosomal dominan transmission. it is probably congenital. three phases in the evolution of lesions: i the "fried eggs" aspect. ii various ophthalmologic aspects: mixed egg, pseudo-hypopion, retractile form. during these first two phases, the yellowish vitelline substance only may extend in macular region, especially downards. iii the atrophic phase. visula acuity remains strangely good, especially during the first two phases. nev ...	2002	130888
[spectral analysis method in veterinary science].		2002	129933
[organization of the veterinary service of a dairy complex].		1975	129913
the effect of butacaine on adenine nucleotide binding and translocation in rat liver mitochondria.	the effect of the local anaesthetic, butacaine, on adenine nucleotide binding and translocation in rat liver mitochondria partially depleted of their adenine nucleotide content was investigated. the range of butacaine concentrations that inhibit adenine nucleotide translocation and the extent of the inhibition are similar to the values obtained for native mitochondria. butacaine does not alter either the total number of atractyloside-sensitive binding sites of depleted mitochondria, or the affin ...	1975	128352
the bad back.		2002	128343
[changes in the lungs and the mass of the right ventricle of the heart in chronic hypoxia (experimental-morphological study)].	in experiments on 105 white rats using histological, histochemical, and morphometric methods the state of the lungs following daily "rises" in a pressure chamber to the "hight" of 5000--9000 m at verious time intervals--from 1 day to 9 weeks was studied. in 18 animals "ascents" were preceded by sinistral pulmonectomy. in parallel, the heart was investigated by the method of separate weighing. at initial stages changes in the lungs were characterized predominantly by impairment of the blood- and ...	1975	128341
[diagnostic importance of calculation of relative measurements of the left atrium in patients with mitral valve defect].		2002	128195
[closed complete dislocations of the crus and the result of their treatment].	based on the analysis of treatment of 22 patients with complete closed crural dislocations, it is emphasized that this trauma is associated with extensive and specific injuries to the articular elements. concomitant injuries of popliteal vessels were found in 4 (of 22) cases. timely performed operative restoration of the arterial integrity yielded favourable late results in 2 patients. two patients admitted in later terms were subjected to a high amputation of the leg. in 15 patients the knee jo ...	2002	128183
in vitro fertilisation of human oöcytes.	this paper describes attempts to cure infertility due to irremediable fallopian tube lesions by the laparoscopic recovery of pre-ovulatory ovarian oöcytes, their fertilisation in vitro, and their subsequent reimplantation into the uterine cavity.	1975	128140
identification and actions of gastric inhibitory polypeptide.		1975	128084
[parameters of digitally averaged potentials of individual motor units].	of sixty normal subjects of different age six different muscles each were examined electromyographically. the activity pattern was recorded for moderate voluntary innervation and superposed digitally. the parameters of digitally averaged summation action potentials were compared with those of manually assessed potentials. the two methods gave identical results: the duration of potentials was between 5 and 10 ms. it increased in the younger and older age groups and showed only slight changes in m ...	2002	128025
disabled living foundation.		2002	127995
[pregnant women and backache].		2002	127867
[role of immune complex in cancer immunity].		2002	127862
synthesis of myosin heavy and light chains in muscle cultures.	the weight ratio of myosin/actin, the myosin heavy chain content as the percentage of total protein (wt/wt), and the kinds of myosin light chains were determined in (a) standard muscle cultures, (b) pure myotube cultures, and (c) fibroblast cultures. cells for these cultures were obtained from the breast of 11-day chick embryos. standard cultures contain, in addition to myotubes, large numbers of replicating mononucleated cells. by killing these replicating cells with cytosine arabinoside, pure ...	2002	127801
immunologic relationship among fibrinolysins secreted by cultured mammalian tumor cells.		1975	127717
closer look: a parent information service.		2002	127706
scattered mitoses in mature joint cartilage in rabbits after local trauma. a chalone effect?	this is a demonstration of local traumatization of articular cartilage inducing mitoses in parts of a joint other than the site of inquiry. parts of one of the patellar cartilages of the full-grown rabbit were scored while the other knee was subjected only to arthrotomy. radioactive thymidine and autoradiographic technique demonstrated that labeled chondrocytes appeared not only around the score in the patella but also scattered in the tibia and femoral condyles. whether the mechanism of regiona ...	1975	127681
[first izolation of enterobacterium a 12 (sachs) in bratislava in the year 1971 (author's transl)].		1975	127664
the hurler syndrome: treatment of cultured hurler fibroblasts with normal human serum.	prolonged replacement of fetal calf serum by normal human serum for the enrichment of medium during tissue culture of hurler fibroblasts resulted in increased acid mucopolysaccharides in the cells and in the medium. the predominant intracellular mucopolysaccharide had the characteristics of dermatan sulfate when hurler cells were treated with either serum. normal human serum contains a nonspecific coreective factor capable of augmenting the loss of 35so4-amps from hurler cells, but not from norm ...	1975	127180
characterization of 5.8s ribosomal ribonucleic acid in neurospora crassa.	neurospora crassa ribosomes contain a species of ribonucleic acid (rna) of molecular weight 54,000, similar to 5.8s ribosomal rna previously described for other eukaryotic organisms. the 5.8s rna from n. crassa was found to be released by heat treatment at 60 c from 25s ribosomal rna but not from 18s ribosomal rna. the base composition of n. crassa 5.8s rna was similar to that of 5.8s rna from saccharomyces cerevisiae, but differed from animal 5.8s rna. during the course of this study, it was di ...	1975	126993
effect of methysergide, a blocker of serotonin receptors, on plasma prolactin levels in lactating and ovariectomized rats.	the effect of methysergide (mes, 2.5 mg/100 g body wt), a serotonin antagonist, on prolactin release has been studied in lactating and ovariectomized rats. mes caused significant increases in prolactin release in both animals. studies in ovariectomized, hypophysectomized rats indicate that this effect is not due to a decrease in the peripheral metabolism of prolactin. in vitro incubations of anterior pituitary fragments with mes failed to demonstrate any increase in prolactin release, suggesting ...	1975	126860
superannuation-1. swindle or bargain?		2002	126445
a day in court could be an unpleasant and costly experience.		2002	126400
behavioral changes following vmh lesions in rats with controlled insulin levels.	the effects of ventromedial hypothalamic (vmh) lesions were studied in female rats made diabetic with streptozotocin that were given twice daily injections of protamine zinc insulin (0.75 mu/100g/day) and in non-diabetic animals of the same sex. hyperphagia resulted from vmh lesions in both diabetic animals whose insulin levels were controlled and in non-diabetic animals. all animals with lesions exhibited persistent increases in feeding during the light protion of the light-dark cycle. signific ...	1975	125424
[possible causes determining the developmental rhythm of populations of the nasopharyngeal gadfly of sheep, oestrus ovis l. (diptera, oestridae)].	on the basis of observations undertaken in azerbaijan and available literary data the author considers the hypotheses concerning the reasons causing the delay of the ist instar larvae development and determining the age structure changes in population of oestrus ovis l. within a year. the main reasons are as follows: factors depending on the population density at the larval phase, the light day duration within the life cycle of the botfly females.	1975	124845
histochemical reactions in the walls of the large intestine in ulcerative colitis.		1998	124801
["masked" supra-renal tumour (author's transl)].	for the diagnosis of supra-renal tumours or tumours of supra-renal rests, it is necessary to employ all available radiological methods as well as the clinical data. two cases are described in which a supra-renal tumour had been "masked" and found at operation. in the first case a cyst in the tail of the pancreas had been considered, in the second, a tumour of the renal hilum or ureter had been diagnosed. it is concluded that in the differential diagnosis of a cyst of the tail of the pancreas, su ...	1998	124685
effects of renal nerves on renal hemodynamics. i. direct stimulation and carotid occlusion.	renal nerves were stimulated either directly (loop electrodes) or indirectly (bilateral carotid occlusion with maintenance of control blood pressure) in anesthetized dogs to determine the effects on renal blood flow (rbf), glomerular filtration rate (gfr), sodium excretion (unav), and intrarenal distribution of blood flow (microsphere method). direct nerve stimulation decreased rbf 20% in 9 of 10 dogs; but gfr, unav, and intrarenal distribution of blood flow did not change significantly. carotid ...	1975	124020
primary hepatic intra-abdominal hemangiopericytoma.		2002	122823
antibiotic usage surveillance: an overview of the issues.		1998	121379
annotations on the measurement of liver ferritin, especially in the rat.		1979	120687
[is breast cancer screening effective? (author's transl)].	two groups of patients consisting of women with and without breast symptoms are compared. they were mammographed in the same institute under identical technical conditions. carcinomas found by screening were considerably less advanced. the findings confirm the experience of numerous authors that screening improves the prognosis; applied tandem method--physical examination and mammography--is far from ideal, but represents at present the best method to reduce breast cancer mortality. the final co ...	2002	120634
[contribution of infectious and parasitic diseases to morbi-mortality rates in ribeirão preto, sp (brazil)].		2002	120605
[congenital ichthyosiform erythroderma. considerations on a clinical case].		2002	120586
[classification of immuno proliferative diseases (author's transl)].		2002	120270
excessive pressure for respiratory therapy.		1999	116529
patterns of virus-immune t-cell responsiveness. comparison of (h-2k x h-2b) leads to h-2b radiation chimeras and negatively selected h-2b lymphocytes.	negatively selected h-2k(b)d(b) tdl can be induced to respond strongly to vaccinia virus presented in the context of both h-2k(k) and h-2d(b) when stimulated in irradiated h-2k(k)d(b) recipients. addition of excess (h- 2k(k)d(b) x h-2k(b)d(b))f1 tdl, which are low responders to h-2d(b)-vaccinia virus, does not obviously suppress the reactivity pattern of the h-2k(b)d(b) t cells. however, lymphocytes from chimeras made by reconstituting h- 2k(b)d(b) mice with (h-2k(k)d(k) x h-2k(b)d(b))f(l) bone ...	1979	115959
failure of anti-d immunoglobulin to remove fetal red cells from maternal circulation.	a rhesus negative female was found post delivery to have circulating cells of fetal origin. the neonate was typed as d-positive. in spite of more than conventionally adequate doses of anti-d immunoglobulin given to the mother, the fetal cell count in the maternal circulation remained unchanged. further investigation showed the fetus to be a du variant and to exhibit a diminished reaction with the batch of anti-d immunoglobulin used.	2000	111422
[on the antimicrobial activity of propolis and propolis constituents (author's transl)].	after a survey of the literature on the antimicrobial activity of the bee product propolis, the authors discuss their own findings as compared to the chemotherapeutical agents streptomycin, oxytetracycline, chloramphenicol, nystatin, griseofulvin and sulphamerazine. according to the results obtained by testing 25 isolated constituents on bacillus subtilis, staphylococcus aureus, candida albicans and trichophyton mentagrophytes, the antimicrobial properties of this mixture of natural substances a ...	1979	108687
acquisition and discrimination of appetitively and aversively conditioned heart rate responses in rhesus monkeys.	this report describes the acquisition of a conditional heart rate response to both classical aversive and appetitive conditioning in eight rhesus monkeys (macaca mulatta). the behavioral paradigm consisted of two discrete one minute tones followed by the corresponding unconditional stimuli, i.e., electric shock or purina monkey chow. a third tone followed by neither food nor shock served as a discriminative stimulus (ds). the conditional heart rate responses developed in two phases. the first ph ...	1978	108656
[feeding of patients following total laryngectomy].		1998	108651
haloperidol treatment of a sixty-year narcotic addiction: case report.		1998	108622
[indications for operation of chronically recurring juvenile appendicitis].		1998	108578
[intensive care at 14 kilometers altitude and 950 kilometers/hr].		1998	108571
[diagnosis of magnesium deficiency should be encouraged (proceedings)].		1998	108548
[irresponsible quarrel concerning mammography guidelines].		1998	108541
[pyruvate and phosphoenolpyruvate carboxylase in methylotrophs].	the activity of pyruvate and phosphoenolpyruvate carboxylases was determined in cell extracts of obligate and facultative methylotrophs which metabolized monocarbon reduced compounds via different pathways. phosphoenolpyruvate carboxylase was found to be the only enzyme responsible for the high level of co2 fixation by methylotrophs with the serine pathway (methylosinus trichosporium, hyphomicrobium vulgare, pseudomonas methylica). methylotrophs with the hexulose phosphate pathway mehylobacter c ...	1979	108526
immobilization of pyridoxal 5'-phosphate and pyridoxal 5'-phosphate-dependent enzymes on sepharose.		1979	108513
[the long term care clinic in falun: active rehabilitation in a nice environment].		1998	108492
influence of exchange volume and dialysate flow rate on solute clearance in peritoneal dialysis.	to find the ideal dialysate flow rate and exchange volume for use in long-term peritoneal dialysis, 10 patients were studied over a period of 1.5 yr. exchange volumes of 1 or 2 liters and dialysate flow rates of 1, 2, 3, 4, and 6 liters/hr were tested. dextrose concentration remained constant at 1.5 g/100 ml. peritoneal clearances for bun, creatinine, and uric acid were calculated at 2, 5, 10, 15, and 20 hr during dialysis making a total of 120 clearances for each patient. all patients used a re ...	1998	108449
gentamycin.		1979	108423
preparation and antibacterial activity upon micrococcus luteus of derivatives of iturin a, mycosubtilin and bacillomycin l, antibiotics from bacillus subtilis.	methylated and acetylated derivatives of iturin a and mycosubtilin and methylated derivatives of bacillomycin l were prepared and their antibacterial activity on micrococcus luteus was compared with the activity of the original substance. the results obtained show the importance of polar groups for the antibiotic activity of the substances of iturin group.	1979	108238
macaca assamensis as a new host for experimental plasmodium knowlesi infection.		1978	108217
a solid-phase radioimmunoassay for bacterial lipopolysaccharide.	a radioimmunoassay for e. coli 055:b5 lipopolysaccharide (lps) is described. the lps was derivatised by two new methods and subsequently radiolabeled with 125i to a specific activity of 2-4 mci/mg without apparent loss in its biophysical, immunological or biological activities. using antibody-coated polystyrene tubes, a solid-phase radioimmunoassay was developed with a sensitivity of 10-500 ng/ml of lps.	1979	108200
formation of non-covalently linked igm polymers: dependence on the protein sulfhydryl groups and zinc ions.		1998	108199
demonstration of human apolipoprotien a in isolated mucosal cells from small intestine and isolated hepatocytes.	isolated mucosal cells from the human jejunum and stomach, cryostat sections from the jejunum, isolated parenchymal liver cells and lymphocytes were investigated for the presence of apolipoprotien a (apoa). antisera against purified human apoa-i and apoa-ii were raised in rabbits and conjugated with fluorescein-isothiocyanate (fitc). mucosal cells from jejunum and stomach were isolated with pronase from tissue obtained from operated patients. apoa-i and apoa-ii could be demonstrated in isolated ...	1979	108182
characteristics of immunoglobulin synthesized early in the development of xenopus laevis.		1979	108156
multiple patterns of induction of rat liver microsomal mono-oxygenases and other polypeptides by xenobiotics [proceedings].		1979	108146
radix puerariae in migraine.		1998	108058
immunoelectrophoretic studies on human small intestinal brush border proteins. a quantitative study of brush border enzymes from single small intestinal biopsies.	a method for measuring brush border membrane enzymes from small intestinal biopsies by crossed immunoelectrophoresis is presented. the use of a brush border specific antiserum made isolation of the brush border membrane before analysis unnecessary. this prevented loss of material which, together with inactivation of enzymes, was a limiting factor in previous studies of brush border enzymes from peroral biopsies. in 58 biopsies from patients without gastrointestinal disorders a close correlation ...	1979	108036
an enzyme-linked immunosorbent assay (elisa) for detecting chicken anti-reovirus antibody at high sensitivity.	an enzyme-linked immunosorbent assay (elisa) with high sensitivity was developed for use in the avian system. anti-reovirus antibody produced in chickens against the isolants s1133, umi-203, reo-25, and winterfield were detected with this method at high titers (up to 1:14,000).	1978	107949
spinal cord evaluation by cortical evoked responses.	in ten monkeys, selective segmental lesions of the dorsal columns at the upper thoracic and middle cervical levels resulted in almost total attenuation of the cortical evoked potential responses to peripheral nerve stimulation. conversely isolated segmental dorsal column preservation showed intact transmission of the evoked responses at rostral spinal cord, nucleus ventralis posterior lateralis, and cortical levels. responses recorded from the intralaminar thalamic nuclei in the region of nucleu ...	1979	107931
two functional types of neurons in the superficial layers of monkey superior colliculus.		1978	107871
[malabsorption syndrome (classification and diagnosis)].		1998	107557
the genetic toxicology of phenoxy acids other than 2,4,5-t.		1998	107443
[acute mesenteric artery thrombosis].		1998	107396
alcohol, malnutrition and liver disease.		1979	107268
rationales for public health insurance coverage of geriatric day care: issues, options, and impacts.	america's long-term care system has been widely criticized for many shortcomings. it relies too heavily upon institutional services, it is too costly, it forces inappropriate levels of care upon patients by offering too few options, in too many instances it offers inferior quality care, and it places too much emphasis on caring for physical ills without concern for enhancing patients' quality of life. alternative modes and settings now under consideration could solve one or more of these problem ...	1998	107220
the health care industry: a case study and future policy issues.		1998	107218
[use of small primates as experimental animals].		1998	107034
baroreceptor control of atrioventricular conduction in man.	although human baroreflexes are known to exert a powerful physiological control on heart rate, little information exists on the physiological control they exert on the atrioventricular conduction system. in 11 normotensive subjects with normal atrioventricular conduction, we altered baroreceptor activity by injection of pressor and depressor drugs (phenylephrine and trinitroglycerin) and recorded mean arterial pressure (map, catheter measurements), r-r interval, and pre-his and post-his interval ...	1979	106985
the role of catecholamines in clinical medicine.	the sympathetic nervous system is of major importance for the regulation of several physiological functions. drugs which inhibit the actions of catecholamines and adrenergic drugs are used in the treatment of many clinical disorders. the potential role of catecholamines in a number of human diseases has, however, until recent years been studied to a limited extent only due to lack of methods for quantitation of sympathetic nervous activity. after the development of enzymatic isotope-derivative a ...	1979	106629
[changes in certain biochemical parameters of rat skin following prolonged gamma irradiation after radioprotection].		1978	106409
[comparative study of methods for the bacterioscopic diagnosis of tuberculosis and of methods for determining drug sensitivity].		1979	106383
[infectious gastroenteritis in childhood].		1998	106240
platelet function and occlusive vascular disease in diabetes mellitus.		1998	106136
crystallography of alpha-lactalbumin. iii. crystals of baboon milk alpha-lactalbumin.		1998	106130
ribosomal dna in drosophila melanogaster. i. isolation and characterization of cloned fragments.		1998	106128
fetal heart rate during a maternal grand mal epileptic seizure.	although maternal ingestion of antiepileptic drugs is strongly suspected of causing congenital defects, particularly oral clefts, the effect of epilepsy itself or a combined effect of drug intake and epilepsy have not been excluded as etiological factors. very little is known about fetal oxygenation during a maternal grand mal epileptic seizure. we describe two cases in which fetal heart rate was recorded during a maternal epileptic seizure during labor. the first fetus became clearly asphyctic ...	1998	106102
food toxins and their implication in human health.		1978	105997
production of antivenom against detoxified taipoxin and immunochemical analysis of the alpha, beta and gamma subunits.		1979	105431
pharmacist directed drug information center--malcolm grow usaf medical center.		1998	105321
nk cell-sensitive t-cell subpopulation in thymus: inverse correlation to host nk activity.		1998	105298
gene complementation in the t-lymphocyte proliferative response to poly (glu55lys36phe9)n. a demonstration that both immune response gene products must be expressed in the same antigen-presenting cell.	the immune response (ir) to the random copolymer glphi depends upon the function of two ir genes, ir-glphi-beta[beta] and ir-glphi-alpha[alpha], mapped to the i-a and i-e/c subregions of the major histocompatibility complex, respectively. in this paper, the site(s) of expression of the products of these two ir genes was examined by evaluating t-lymphocyte proliferative responses of bone marrow radiation chimeras. chimeras were created in [alpha+beta- x alpha-beta+]f1 responder mice by lethal irr ...	1998	105077
homology of the gene coding for outer membrane lipoprotein within various gram-negative bacteria.	the mrna for a major outer membrane lipoprotein from escherichia coli was found to hybridize specifically with one of the ecori and one of the hindiii restriction endonuclease-generated fragments of total dna from nine bacteria in the family enterobacteriaceae: e. coli, shigella dysenteriae, salmonella typhimurium, citrobacter freundii, klebsiella aerogenes, enterobacter aerogenes, edwardsiella tarda, serratia marcescens, and erwinia amylovora. however, among the enterobacteriaceae, dna from two ...	1979	104972
dynamics of corneo-scleral envelope.		1978	104926