Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
|---|
| regulatory t cell-like responses in deer mice persistently infected with sin nombre virus. | hantavirus cardiopulmonary syndrome is a zoonotic illness associated with a systemic inflammatory immune response, capillary leak, noncardiogenic pulmonary edema, and shock in humans. cytokines, including tnf, ifn-gamma, and lymphotoxin, are thought to contribute to its pathogenesis. in contrast, infected rodent reservoirs of hantaviruses experience few or no pathologic changes and the host rodent can remain persistently infected for life. generally, it is unknown why such dichotomous immune res ... | 2007 | 17875986 |
| delayed density-dependent prevalence of sin nombre virus antibody in montana deer mice (peromyscus maniculatus) and implications for human disease risk. | american hantaviruses cause a severe respiratory disease known as hantavirus pulmonary syndrome (hps). in the united states, sin nombre virus (snv), carried by the deer mouse ( peromyscus maniculatus), is the etiologic agent in the majority of hps cases. the relationship between deer mouse population density and snv infection prevalence in deer mice is poorly understood. our purpose was to clarify this relationship by demonstrating the existence of delayed-density-dependent prevalence of snv inf ... | 2007 | 17767405 |
| conjunctival lymphoid follicles in new world rodents. | we report for the first time, the detection of conjunctival lymphoid follicles (clf) in the eyes of new world rodents. clf were found in 7 of the 15 species examined, 6 of the 10 genera, and in at least one individual in four families of rodents. these follicles are dense collections of leukocytes in the conjunctival substantia propria with a thinned overlying epithelium lacking in goblet cells. although the precise location of clf within the conjunctiva varied from species to species, all clf w ... | 2007 | 17722097 |
| differential resource allocation in deer mice exposed to sin nombre virus. | the resource allocation hypothesis predicts that reproductive activity suppresses immunocompetence; however, this has never been tested in an endemic disease system with free-ranging mammals. we tested the resource allocation hypothesis in wild deer mice (peromyscus maniculatus) with natural exposure to sin nombre virus (snv). immunocompetence was estimated from the extent of swelling elicited after deer mice were injected with phytohemagglutinin (pha); swelling is positively correlated with imm ... | 2007 | 17717814 |
| digestive responses of two omnivorous rodents (peromyscus maniculatus and p. alstoni) feeding on epigeous fungus (russula occidentalis). | the sporocarps of hypogeous and epigeous fungi are important dietary items for forest dwelling rodents in temperate and tropical forests throughout the world. however, results of some pioneering works have demonstrated that fungi cannot be considered as nutritionally high-quality food items for some mycophagous small rodents. according to these studies, when mycophagous rodents feed on fungus, they showed a minimal digestibility, but whether this applies to most rodent species that include fungi ... | 2007 | 17653726 |
| body size variation of mammals in a fragmented, temperate rainforest. | body size is perhaps the most important trait of an organism, affecting all of its physiological and ecological processes and, therefore, fundamentally influencing its ability to survive and reproduce in different environments, including those that have been modified by human activities. we tested the hypothesis that anthropogenic transformation of old-growth forest landscapes can result in significant intraspecific changes in body size of resident biotas. we collected data on five species of no ... | 2007 | 17650255 |
| prevalence of cryptosporidium species in wildlife populations within a watershed landscape in southeastern new york state. | a cross-sectional study was conducted to determine the prevalence of cryptosporidium in wildlife in the new york city (nyc) watershed in southeastern new york state. a total of 6227 fecal samples were collected and evaluated from 5892 mammals (38 species), 263 birds (14 species), 2 reptiles (2 species), 8 amphibians (4 species), and 62 fish (15 species). cryptosporidium was detected in 30 species. of the species found positive for cryptosporidium, 16 represented new records for this parasite-alo ... | 2007 | 17466459 |
| small mammals as indicators of short-term and long-term disturbance in mixed prairie. | disturbance by military maneuvers over short and long time scales may have differential effects on grassland communities. we assessed small mammals as indicators of disturbance by military maneuvers in a mixed prairie in southern oklahoma usa. we examined sites on two soil series, foard and lawton, across a gradient of disturbance intensity. a manova showed that abundance of small mammals was associated (p = 0.03) with short-term (cover of vehicle tracks) disturbance but was not associated (p = ... | 2008 | 17458511 |
| the molecular basis of high-altitude adaptation in deer mice. | elucidating genetic mechanisms of adaptation is a goal of central importance in evolutionary biology, yet few empirical studies have succeeded in documenting causal links between molecular variation and organismal fitness in natural populations. here we report a population genetic analysis of a two-locus alpha-globin polymorphism that underlies physiological adaptation to high-altitude hypoxia in natural populations of deer mice, peromyscus maniculatus. this system provides a rare opportunity to ... | 2007 | 17397259 |
| hpa activity and neotic and anxiety-like behavior vary among peromyscus species. | behaviorally plastic species are more likely to invade and endure in new areas, and behaviorally plastic individuals tend to be attracted to novelty (i.e., neophilic). furthermore, neophilic behaviors are often influenced by glucocorticoids. thus in addition to environmental conditions and vicariant events, behavioral plasticity and its endocrinological mediators may influence the extent of vertebrate geographic distributions. some species of mice in the genus, peromyscus, occupy most of north a ... | 2007 | 17368638 |
| two cases of hantavirus pulmonary syndrome in randolph county, west virginia: a coincidence of time and place? | hantavirus pulmonary syndrome (hps) is caused by an infection with viruses of the genus hantavirus in the western hemisphere. rodent hosts of hantaviruses are present throughout the united states. in july 2004, two hps case-patients were identified in randolph county, wv: a wildlife science graduate student working locally and a randolph county resident. we interviewed family members and colleagues, reviewed medical records, and conducted environmental studies at likely exposure sites. small mam ... | 2007 | 17360864 |
| tularemia in deer mice (peromyscus maniculatus) during a population irruption in saskatchewan, canada. | type b tularemia caused by francisella tularensis subsp. holarctica was diagnosed in deer mice (peromyscus maniculatus) found dead at four sites in west-central saskatchewan during april and may 2005. the occurrence of tularemia coincided with a decline in the number of deer mice in part of a large area (>22000 km(2) ) in which deer mice had been extremely abundant during the autumn of 2004 and spring of 2005, and in which mice caused damage to crops in the autumn of 2004. this is apparently the ... | 2007 | 17347390 |
| sin nombre virus infection of deer mice in montana: characteristics of newly infected mice, incidence, and temporal pattern of infection. | sin nombre virus (snv), hosted by the deer mouse (peromyscus maniculatus), is the principal cause of hantavirus pulmonary syndrome (hps) in north america. to improve our understanding of factors that contribute to the occurrence of hps, we conducted an extensive field study of the characteristics of newly infected (as determined by recent acquisition of antibody) deer mice and the temporal pattern of antibody acquisition (seroconversion) from 1994 through 2004 in montana, usa. we sampled 6,584 i ... | 2007 | 17347389 |
| demographic factors associated with prevalence of antibody to sin nombre virus in deer mice in the western united states. | we used long-term data collected for up to 10 yr (1994-2004) at 23 trapping arrays (i.e., webs and grids) in arizona, colorado, montana, and new mexico to examine demographic factors known or suspected to be associated with risk of infection with sin nombre virus (snv) in its natural host, the deer mouse (peromyscus maniculatus). gender, age (mass), wounds or scars, season, and local relative population densities were statistically associated with the period prevalence of antibody (used as a mar ... | 2007 | 17347388 |
| age dependent acute oral toxicity of hexahydro-1,3,5-trinitro-1,3,5-triazine (rdx) and two anaerobic n-nitroso metabolites in deer mice (peromyscus maniculatus). | hexahydro-1,3,5-trinitro-1,3,5-triazine (rdx) transforms anaerobically into n-nitroso compounds: hexahydro-1-nitroso-3,5-dinitro-1,3,5-triazine (mnx), hexahydro-1,3-dinitroso-5-nitro-1,3,5-triazine (dnx), and hexahydro-1,3,5-trinitroso-1,3,5-triazine (tnx). exposure to these n-nitroso metabolites may occur in areas contaminated with explosives, as anaerobic degradation occurs via some bacteria and is one remediation strategy used for rdx. few papers report acute oral toxicity and none have evalu ... | 2007 | 17275885 |
| changes in sin nombre virus antibody prevalence in deer mice across seasons: the interaction between habitat, sex, and infection in deer mice. | we examined the impact of season and habitat on sin nombre virus (snv) seroprevalence in deer mice (peromyscus maniculatus) in utah's great basin desert from may 2002 through summer 2003. low mouse captures in 2002 limited analysis for that year. in two seasons during 2003, mouse density and sagebrush cover were positively linked (spring: r = 0.8, p = 0.01; summer: r = 0.8, p = 0.04). in the spring, seroprevalence was negatively correlated with density (r = -0.9, p< 0.01); male and female antibo ... | 2006 | 17255449 |
| deer mouse movements in peridomestic and sylvan settings in relation to sin nombre virus antibody prevalence. | prevalence of antibody to sin nombre virus (snv) has been found to be nearly twice as high in deer mice (peromyscus maniculatus) in peridomestic settings as in sylvan settings in two studies in montana and one in new mexico. we investigated whether this difference may be related to a difference in deer mouse movements in the two settings. we used radiotelemetry to determine home range size and length of movement for 22 sylvan (1991-1992) and 40 peridomestic deer mice (1995-1999). we also determi ... | 2006 | 17255448 |
| n-nitroso compounds produced in deer mouse (peromyscus maniculatus) gi tracts following hexahydro-1,3,5-trinitro-1,3,5-triazine (rdx) exposure. | given the potent carcinogenic effects of most n-nitroso compounds, the reductive transformation of the common explosive hexahydro-1,3,5-trinitro-1,3,5-triazine (rdx) to a group of n-nitroso derivatives, hexahydro-1-nitroso-3,5-dinitro-1,3,5-triazine (mnx), hexahydro-1,3-dinitroso-5-nitro-1,3,5-triazine (dnx), and hexahydro-1,3,5-trinitroso-1,3,5-triazine (tnx) in the environment have caused concerns among the general public. questions are arising about whether the same transformations also occur ... | 2007 | 17223165 |
| use of igg avidity to indirectly monitor epizootic transmission of sin nombre virus in deer mice (peromyscus maniculatus). | an igg avidity assay was developed to differentiate deer mice that had recently acquired sin nombre virus (snv) from those that were infected in the distant past. using this procedure, low avidity antibodies were predominantly detected in experimentally infected deer mice (89.5%) within the first 30 days post-inoculation. the assay was then applied to sera from naturally infected deer mice collected during a field investigation associated with a cluster of hantavirus pulmonary syndrome cases. a ... | 2006 | 17172381 |
| photoperiod affects daily torpor and tissue fatty acid composition in deer mice. | photoperiod and dietary lipids both influence thermal physiology and the pattern of torpor of heterothermic mammals. the aim of the present study was to test the hypothesis that photoperiod-induced physiological changes are linked to differences in tissue fatty acid composition of deer mice, peromyscus maniculatus ( approximately 18-g body mass). deer mice were acclimated for >8 weeks to one of three photoperiods (ld, light/dark): ld 8:16 (short photoperiod), ld 12:12 (equinox photoperiod), and ... | 2007 | 17160415 |
| schistosome infection in deer mice (peromyscus maniculatus): impacts on host physiology, behavior and energetics. | animals routinely encounter environmental stressors and may employ phenotypic plasticity to compensate for the costs of these perturbations. parasites represent an ecologically important stressor for animals, which may induce host plasticity. the present study examined the effects of a trematode parasite, schistosomatium douthitti, on deer mouse (peromyscus maniculatus) physiology, behavior and energetics. measures were taken to assess direct parasite pathology as well as potential host plastici ... | 2006 | 17142691 |
| small mammals and forest fuel reduction: national-scale responses to fire and fire surrogates. | forest fuel reduction treatments are increasingly used by managers to reduce the risk of high-severity wildfire and to manage changes in the ecological function of forests. however, comparative ecological effects of the various types of treatments are poorly understood. we examined short-term patterns in small-mammal responses to mechanical thinning, prescribed-fire, and mechanical thinning/prescribed-fire combination treatments at eight different study areas across the united states as a part o ... | 2006 | 17069366 |
| age-dependent characterization of pendrin gene expression in various tissues of deer mice. | pendrin is a membrane transport protein which functions as the transporter of chloride, bicarbonate, formate, and iodide. in this study, we characterized pendrin gene expression in various tissues of deer mice (peromyscus maniculatus), a sentinel wildlife species. deer mice were euthanized at post-natal day (pnd) 21 (day of weaning) and pnd 45 (24 days post-weaning) for tissue collection. a deer mouse-specific partial pendrin cdna sequence was generated, from which taqman-specific probe and prim ... | 2006 | 17055311 |
| prevalence of borrelia burgdorferi in small mammals in new york state. | intensive small mammal trapping was conducted in 12 counties in new york state during 1998-2000 to investigate the prevalence and site specificity of the lyme disease spirochete, borrelia burgdorferi in, and presence of the blacklegged tick, ixodes scapularis say on, the wild mice peromyscus leucopus rafinesque and peromyscus maniculatus wagner and other small mammal species. previously captured mice (1992-1997) from throughout new york state also were recruited into the study, providing a total ... | 2006 | 17017230 |
| refractoriness of the western fence lizard (sceloporus occidentalis) to the lyme disease group spirochete borrelia bissettii. | the western fence lizard, sceloporus occidentalis, is refractory to experimental infection with borrelia burgdorferi sensu stricto, one of several lyme disease spirochetes pathogenic for humans. another member of the lyme disease spirochete complex, borrelia bissettii, is distributed widely throughout north america and a similar, if not identical, spirochete has been implicated as a human pathogen in southern europe. to determine the susceptibility of s. occidentalis to b. bissettii, 6 naïve liz ... | 2006 | 16995383 |
| profiling helper t cell subset gene expression in deer mice. | deer mice (peromyscus maniculatus) are the most common mammals in north america and are reservoirs for several zoonotic agents, including sin nombre virus (snv), the principal etiologic agent of hantavirus cardiopulmonary syndrome (hcps) in north america. unlike human hcps patients, snv-infected deer mice show no overt pathological symptoms, despite the presence of virus in the lungs. a neutralizing igg antibody response occurs, but the virus establishes a persistent infection. limitations of de ... | 2006 | 16916450 |
| immunological memory is compromised by food restriction in deer mice peromyscus maniculatus. | the immune system protects organisms against infection, but this protection presumably comes at a cost. here, we asked whether food restriction would compromise the ability of an organism to generate an immune response on reexposure to an antigen, which would represent a functional cost of immunological memory. immunological memory is generated when b and t lymphocytes sensitive to components of pathogens (i.e., antigens) proliferate after exposure and persist in circulation to hinder reinfectio ... | 2007 | 16902185 |
| is bmr repeatable in deer mice? organ mass correlates and the effects of cold acclimation and natal altitude. | basal metabolic rate (bmr) is probably the most studied aspect of energy metabolism in vertebrate endotherms. numerous papers have explored its mass allometry, phylogenetic and ecological relationships, and ontogeny. implicit in many of these studies (and explicit in some) is the view that bmr responds to selection, which requires repeatability and heritability. however, bmr is highly plastic in response to numerous behavioral and environmental factors and there are surprisingly few data on its ... | 2007 | 16897038 |
| host usage and seasonal activity patterns of ixodes kingi and i. sculptus (acari: ixodidae) nymphs in a colorado prairie landscape, with a summary of published north american host records for all life stages. | we examined host usage and seasonal activity patterns of the nymphal stage of the ticks ixodes kingi and i. sculptus within a prairie rodent community in north-central colorado. ixodes kingi was commonly encountered on both northern grasshopper mice (onychomys leucogaster) and thirteen-lined ground squirrels (spermophilus tridecemlineatus), whereas i. sculptus frequently infested s. tridecemlineatus but was absent from o. leucogaster. low numbers of ticks of both species were collected from deer ... | 2006 | 16859106 |
| genealogical concordance and the specific status of peromyscus sejugis. | peromyscus sejugis, a peripheral isolate of peromyscus maniculatus, is a threatened taxon endemic to 2 small islands in the sea of cortés. although its insularity makes the specific recognition of p. sejugis inherently problematic, resolution of this problem has important conservation implications. to evaluate the specific validity and evolutionary history of p. sejugis, we compared sequence variation (nd3/nd4l/nd4) in mtdna for both island populations of p. sejugis with that for 8 populations o ... | 2006 | 16785280 |
| hantavirus pulmonary syndrome--five states, 2006. | hantavirus pulmonary syndrome (hps) is a rodentborne viral disease characterized by severe pulmonary illness and a case-fatality ratio of 30%-40%. sin nombre virus causes the majority of hps cases in the united states, and the deer mouse (peromyscus maniculatus) is its predominant reservoir. this report describes an increase in human cases of hps reported during january-march 2006 from arizona, new mexico, north dakota, texas, and washington state. the findings emphasize the need for renewed att ... | 2006 | 16760891 |
| phylogeography of the deer mouse (peromyscus maniculatus) provides a predictive framework for research on hantaviruses. | phylogeographical partitioning of sin nombre and monongahela viruses (hantaviruses) may reflect that of their primary rodent host, the deer mouse (peromyscus maniculatus). lack of a comprehensive assessment of phylogeographical variation of the host has precluded the possibility of predicting spatial limits of existing strains of these viruses or geographical regions where novel viral strains might emerge. the complete cytochrome b gene was sequenced for 206 deer mice collected from sites throug ... | 2006 | 16760402 |
| mammal and flea relationships in the great basin desert: from h. j. egoscue's collections. | host-parasite association among 58 flea species parasitizing 40 mammal species in the great basin desert of the western united states was investigated. increased flea species richness was correlated with larger geographic ranges and stable locomotion of hosts. hosts from habitats of moderately low productivity (sage and grass) and of peromyscus maniculatus size, 10-33 g, had the highest flea species richness. larger hosts had fewer flea species, but fleas were more prevalent. increased host spec ... | 2006 | 16729681 |
| jaw muscle functional anatomy in northern grasshopper mouse, onychomys leucogaster, a carnivorous murid. | the jaw muscle anatomy of the northern grasshopper mouse, onychomys leucogaster, was observed and the mechanical basis of the insectivorous/carnivorous adaptations were examined. compared with peromyscus maniculatus, a granivorous relative of onychomys, there is a reduction of some aponeuroses within the masseter deep layer. this characteristic indicates that shearing meat or crushing arthropod exoskeletons requires less occlusal pressure than does grinding plant material. in onychomys both the ... | 2006 | 16710844 |
| thyroid function and reproductive success in rodents exposed to perchlorate via food and water. | the purpose of the present study was to determine if exposure to perchlorate via food items would have effects on mammals similar to those caused by exposure through drinking water at approximately equivalent doses. prairie voles (microtus ochrogaster) and deer mice (peromyscus maniculatus) were used to assess the potential toxicity of perchlorate-contaminated food items. voles and mice were divided randomly into three treatment groups--perchlorate-contaminated food (pcf), perchlorate-contaminat ... | 2006 | 16629144 |
| biological control agents elevate hantavirus by subsidizing deer mouse populations. | biological control of exotic invasive plants using exotic insects is practiced under the assumption that biological control agents are safe if they do not directly attack non-target species. we tested this assumption by evaluating the potential for two host-specific biological control agents (urophora spp.), widely established in north america for spotted knapweed (centaurea maculosa) control, to indirectly elevate sin nombre hantavirus by providing food subsidies to populations of deer mice (pe ... | 2006 | 16623730 |
| phylogeographic population structure of red-winged blackbirds assessed by mitochondrial dna. | a continent-wide survey of restriction-site variation in mitochondrial dna (mtdna) of the red-winged blackbird (agelaius phoeniceus) was conducted to assess the magnitude of phylogeographic population structure in an avian species. a total of 34 mtdna genotypes was observed among the 127 specimens assayed by 18 restriction endonucleases. nonetheless, population differentiation was minor, as indicated by (i) small genetic distances in terms of base substitutions per nucleotide site between mtdna ... | 1988 | 16593914 |
| susceptibility of various species of rodents to the relapsing fever spirochete, borrelia hermsii. | in a study to determine susceptibility to borrelia hermsii of various rodents commonly found in or near places where human cases of relapsing fever occurred, chipmunks (eutamias amoenus), pine squirrels (tamiasciurus hudsonicus richardsoni), flying squirrels (glaucomys sabrinus), columbian ground squirrels (spermophilus columbianus columbianus), golden-mantled ground squirrels (s. lateralis tescorum), wood rats (neotoma cinerea cinerea), white-footed deer mice (peromyscus maniculatus), and meado ... | 1970 | 16557828 |
| reproductive effects of hexahydro-1,3,5-trinitroso-1,3,5-triazine in deer mice (peromyscus maniculatus) during a controlled exposure study. | contamination with hexahydro-1,3,5-trinitro-1,3,5-triazine (royal demolition explosive [rdx]) has been identified at areas of explosive manufacturing, processing, storage, and usage. thus, the potential exists for exposure to n-nitroso compounds, hexahydro-1-nitroso-3,5-dinitro-1,3,5-triazine, hexahydro-1,3-dinitroso-5-nitro-1,3,5-triazine, and hexahydro-1,3,5-trinitroso-1,3,5-triazine (tnx), formed via anaerobic transformation of rdx. following exposure, reproductive toxicity of tnx was evaluat ... | 2006 | 16519305 |
| prevalence of bordetella bronchiseptica in certain central iowa. | bordetella bronchiseptica was isolated from 6 of 13 short-tailed shrews (blarina brevicauda) and 1 of 47 house sparrows (passer domesticus) trapped in the vicinity of a swine bordetella rhinitis experimental area. the organism was found in four of 50 foxes (vulpes fulva), 2 of 36 opossums (didelphis marsupialis) and 1 of 37 raccoons (procyon lotor) trapped in the ames, iowa area. this bacterium was not culturally isolated from 14 deer mice (peromyscus maniculatus), 64 house mice (mus musculus), ... | 1976 | 16502690 |
| development of a deer mouse whole-genome radiation hybrid panel and comparative mapping of mus chromosome 11 loci. | a 5000-rad whole-genome radiation hybrid cell panel (bw5000) was developed for mapping the deer mouse (peromyscus maniculatus bairdii) genome. the panel consists of 103 cell lines and has an estimated marker retention frequency of 63.9% (range, 28%-88%) based on pcr typing of 30 type i (coding gene) and 25 type ii (microsatellite) markers. using the composite mus map, type i markers were selected from six mus chromosomes, 22 of which are on mus chr 11. fifteen of the mus chr 11 markers were simu ... | 2006 | 16416089 |
| mystr: an endogenous retrovirus family in mammals that is undergoing recent amplifications to unprecedented copy numbers. | a large percentage of the repetitive elements in mammalian genomes are retroelements, which have been moved primarily by line-1 retrotransposons and endogenous retroviruses. although line-1 elements have remained active throughout the mammalian radiation, specific groups of endogenous retroviruses generally remain active for comparatively shorter periods of time. identification of an unusual extinction of line-1 activity in a group of south american rodents has opened a window for examination of ... | 2005 | 16282470 |
| long-term dynamics of sin nombre viral rna and antibody in deer mice in montana. | infections with hantaviruses in the natural host rodent may result in persistent, asymptomatic infections involving shedding of virus into the environment. laboratory studies have partially characterized the acute and persistent infection by sin nombre virus (snv) in its natural host, the deer mouse (peromyscus maniculatus). however, these studies have posed questions that may best be addressed using longitudinal studies involving sequential sampling of individual wild-caught, naturally infected ... | 2005 | 16244056 |
| the eye of the laboratory mouse remains anatomically adapted for natural conditions. | evolutionary effects of domestication have been demonstrated for several body systems, including the eye, and for several vertebrate species, including the mouse. given the importance of the laboratory mouse to vision science, we wished to determine whether the anatomical and histological features of the eyes of laboratory mice are distinct from those of their naturally adapted, wild counterparts. we measured dimensions and masses of whole eyes and lenses from a wild population plus three inbred ... | 2006 | 16219997 |
| attempted isolation of blastomyces dermatitidis from native shrews in northern wisconsin, usa. | the precise ecological niche of blastomyces dermatitidis is unknown. the related dimorphic fungus, paracoccidioides brasiliensis, has been isolated from south american ground-dwelling insectivorous armadillos. we attempted to isolate blastomyces from shrews, north american ground-dwelling insectivores that have been shown to harbor histoplasma capsulatum in endemic areas. forty-seven masked shrews (sorex cinereus) and 13 northern short-tailed shrews (blarina brevicauda) were collected in endemic ... | 2005 | 16178369 |
| peromyscus populations and their cuterebra parasites display congruent phylogeographical structure. | the relationships between populations of the deer mouse (peromyscus maniculatus) and the white-footed mouse (p. leucopus) and their respective cuterebra parasites were examined. population genetic structure of hosts and parasites was inferred using cytochrome oxidase mitochondrial sequences of specimens from 7 populations. genetic analyses revealed that isolation-by-distance applies for p. maniculatus and its associated parasite (c. grisea). a significant correlation was also observed between th ... | 2005 | 16145940 |
| replication and immunoactivity of the recombinant peromyscus maniculatus cytomegalovirus expressing hantavirus g1 glycoprotein in vivo and in vitro. | previously, we have shown that cmv isolated from deer mouse could be used in vivo and in vitro to express sin nombre virus (snv) glycoprotein g1 in deer mice [rizvanov aa, van geelen ag, morzunov s, et al. generation of a recombinant cytomegalovirus for expression of a hantavirus glycoprotein. j.virol. 2003;77(22):12203-10]. in this report, we further characterize replication of wild-type (wt) and recombinant peromyscus cmv (pcmv) in vivo and in vitro using realtime pcr, and infectious center as ... | 2006 | 16125285 |
| a preliminary study of the patterns of sin nombre viral infection and shedding in naturally infected deer mice (peromyscus maniculatus). | deer mice (peromyscus maniculatus) were trapped in southern manitoba, canada and tested for evidence of sin nombre virus infection. viral genome was amplified from tissues as well as saliva/oropharyngeal fluid, and urine samples were collected from seropositive animals. detection of viral rna in tissue samples and excreta/secreta from mice suggest that differences may exist between naturally infected rodents with respect to viral shedding. | 2005 | 16011428 |
| two-phase seed dispersal: linking the effects of frugivorous birds and seed-caching rodents. | frugivorous birds disperse the seeds of many fruit-bearing plants, but the fate of seeds after defecation or regurgitation is often unknown. some rodents gather and scatter hoard seeds, and some of these may be overlooked, germinate, and establish plants. we show that these two disparate modes of seed dispersal are linked in some plants. rodents removed large (>25 mg) seeds from simulated bird feces (pseudofeces) at rates of 8-50%/day and scatter hoarded them in soil. ants (formica sibylla) also ... | 2005 | 15959820 |
| development and evaluation of serological assays for detection of human hantavirus infections caused by sin nombre virus. | the hantavirus cardiopulmonary syndrome (hcps) was first recognized in 1993 after a cluster of acute respiratory distress syndrome deaths in the southwestern of the united states. the major causative agent of hcps in north america is the sin nombre virus (snv) carried by the deer mouse peromyscus maniculatus. the first hcps case imported to europe was reported in 2002. | 2005 | 15911448 |
| ants as first intermediate hosts of mesocestoides on san miguel island, usa. | this study tested the hypotheses that ants (formicidae) function as a first intermediate host of mesocestoides (cestoda: mesocestoididae) and that deer mice (peromyscus maniculatus) develop metacestode infections after ingesting cysticercoid or procercoid-infected ants. field studies were conducted at an island fox (urocyon littoralis littoralis) breeding facility located on san miguel island, california channel islands national park, usa, where > 40% of captive foxes were infected with adult me ... | 2005 | 15831116 |
| population dynamics of a diverse rodent assemblage in mixed grass-shrub habitat, southeastern colorado, 1995-2000. | we followed seasonal and year-to-year population dynamics for a diverse rodent assemblage in a short-grass prairie ecosystem in southeastern colorado (usa) for 6 yr. we captured 2,798 individual rodents (range, one to 812 individuals per species) belonging to 19 species. the two most common species, deer mice (peromyscus maniculatus) and western harvest mice (reithrodontomys megalotis), generally had population peaks in winter and nadirs in summer; several other murid species demonstrated autumn ... | 2005 | 15827207 |
| epizootiology of sin nombre and el moro canyon hantaviruses, southeastern colorado, 1995-2000. | sin nombre virus (snv) is an etiologic agent of hantavirus pulmonary syndrome. to better understand the natural history of this virus we studied population dynamics and temporal pattern of infection of its rodent hosts in southeastern colorado (usa) from 1995 to 2000. we present evidence for the presence of two hantaviruses, snv in deer mice (peromyscus maniculatus) and el moro canyon virus in western harvest mice (reithrodontomys megalotis), at our study sites. sin nombre virus appeared only sp ... | 2005 | 15827206 |
| rodent-flea-plague relationships at the higher elevations of san diego county, california. | rodent-flea-plague relationships were examined at sites located at higher elevations of san diego county during 1991-2002. the most frequently sampled rodents were the california ground squirrel, spermophilus beecheyi, and white-footed mice, peromyscus spp. higher seasonal mean dependent variables (prevalences of squirrels and indices of o. montana), higher mean amounts of seasonal rainfall, and lower seasonal mean ambient temperatures were found at sites during 1991--1993 compared with 2000--20 ... | 2004 | 15707283 |
| estrogen receptor alpha and vasopressin in the paraventricular nucleus of the hypothalamus in peromyscus. | the purpose of this study was to determine the presence of estrogen receptor alpha (eralpha) and the relationship between neurons that express eralpha and produce vasopressin (avp) in the paraventricular nucleus of the hypothalamus (pvn) in new world mice of the genus peromyscus. brains were collected from male and female peromyscus californicus, peromyscus leucopus, peromyscus maniculatus, and peromyscus polionotus, and double labeled for the expression of eralpha and avp immunoreactivity (ir). ... | 2005 | 15680954 |
| microsatellite variation and evolution in the peromyscus maniculatus species group. | variation at 12 pure-repeat dinucleotide microsatellites from peromyscus maniculatus was analyzed for samples of all species in the p. maniculatus species group and p. leucopus. except for one locus (pml08) that amplified a product only for p. maniculatus, these microsatellites yielded reliable estimates of variation across these species; per-locus polymorphism and allele-size distribution were not significantly different among or between any of the species sampled from mainland populations. sig ... | 2005 | 15619451 |
| identification of a monoclonal antibody from peromyscus maniculatus (deer mouse) cytomegalovirus (pcmv) which binds to a protein with homology to the human cmv matrix protein hcmv pp71. | in this study we identified and characterized a monoclonal antibody against the matrix protein of a cytomegalovirus isolated from the common deer mouse (peromyscus maniculatus) (pcmv). the monoclonal antibody was isolated using previously described technology which could be applied to the production of monoclonal antibodies against zoonotic disease. the antibody was found to react with a protein homologous to the human cytomegalovirus (hcmv) matrix protein (pp71), the product of the ul82 open re ... | 2005 | 15582693 |
| generation of competent bone marrow-derived antigen presenting cells from the deer mouse (peromyscus maniculatus). | human infections with sin nombre virus (snv) and related new world hantaviruses often lead to hantavirus cardiopulmonary syndrome (hcps), a sometimes fatal illness. lungs of patients who die from hcps exhibit cytokine-producing mononuclear infiltrates and pronounced pulmonary inflammation. deer mice (peromyscus maniculatus) are the principal natural hosts of snv, in which the virus establishes life-long persistence without conspicuous pathology. little is known about the mechanisms snv employs t ... | 2004 | 15458574 |
| eubrachylaelaps debilis, a new laelaptid mite (acarina: laelaptidae) parasitic on the deer mouse, peromyscus maniculatus (mammalia: cricetidae). | 1950 | 15402958 | |
| effects of trichloroethylene and perchloroethylene on wild rodents at edwards air force base, california, usa. | effects of inhalation of volatilized trichloroethylene (tce) or perchloroethylene (pce) were assessed based on the health and population size of wild, burrowing mammals at edwards air force base (ca, usa). organic soil-vapor concentrations were measured at three sites with aquifer contamination of tce or pce of 5.5 to 77 mg/l and at two uncontaminated reference sites. population estimates of kangaroo rats (dipodomys merriami and d. panamintinus) as well as hematology, blood chemistry, and histop ... | 2004 | 15378993 |
| detection and characterization of borrelia bissettii in rodents from the central california coast. | this is the first report of borrelia burgdorferi sensu lato in rodents from san luis obispo county, with most isolates obtained from a previously unreported host, neotoma lepida thomas. b. burgdorferi sensu lato was identified in seven rodent species, including the california vole, microtus californicus peale; dusky-footed woodrat, neotoma fuscipes baird; desert woodrat, neotoma lepida thomas; brush mouse, peromyscus boylii baird; california mouse, peromyscus californicus gambel; deer mouse, per ... | 2004 | 15311469 |
| natural selection drives altitudinal divergence at the albumin locus in deer mice, peromyscus maniculatus. | in populations that are distributed across steep environmental gradients, the potential for local adaptation is largely determined by the spatial scale of fitness variation relative to dispersal distance. since altitudinal gradients are generally characterized by dramatic ecological transitions over relatively short linear distances, adaptive divergence across such gradients will typically require especially strong selection to counterbalance the homogenizing effect of gene flow. here we report ... | 2004 | 15266982 |
| genetic relatedness of deer mice (peromyscus maniculatus) infected with sin nombre virus. | the deer mouse (peromyscus maniculatus) is the primary rodent host of sin nombre virus (snv), the principal etiologic agent of hantavirus pulmonary syndrome in the united states. many characteristics of snv infections of deer mice are unknown. to better understand the transmission mechanisms of snv in deer mice, we conducted mark-recapture sampling and genetic analyses to study deer mouse population density and genetic relatedness from 2001 to 2002. we genotyped each deer mouse at 10 microsatell ... | 2004 | 15228816 |
| concentrations of metals in mink and other mammals from washington and idaho. | from 1981 to 1983, concentrations of metals were determined in mink mustela vison, muskrats ondatra zibethica, and small mammals at one contaminated site in idaho and at two less contaminated sites in idaho and washington. the highest concentrations of pb and cd occurred in samples from the coeur d'alene river system near or downstream from an extensive mining-smelting complex in northern idaho. maximum concentrations of pb in the liver of a mink (22 microg g(-1)) and in pooled liver samples of ... | 1987 | 15092768 |
| effect of smelter emissions on the hemogram of the deer mouse (peromyscus maniculatus). | blood samples were obtained from 284 deer mice (peromyscus maniculatus) live-trapped near two base metal smelters in northern manitoba, canada. hemoglobin and hematocrit values were significantly higher in mice trapped within 40-70 km of the smelters compared to those in control areas 185 to 190 km from the smelter. these increases appear to be normal physiological responses to a mild respiratory stress, as in a true secondary polycythemia of anoxic tupe. the mice are sensitive bioindicators of ... | 1988 | 15092500 |
| element content in tissues of four rodent species sampled in the geysers geothermal steamfield. | liver and kidney tissue samples from four rodent species collected in the geysers geothermal steamfield of northern california were analyzed for content of 28 elements. element concentrations in samples from the developed region of the geysers were compared with samples from undeveloped reference regions to determine the influence of geothermal power development on element content in small mammal tissues. eight elements (b, ca, cu, mg, mn, p, sr, ti) were enriched in samples from the geysers, 12 ... | 1989 | 15092429 |
| life-history studies on two molecular strains of mesocestoides (cestoda: mesocestoididae): identification of sylvatic hosts and infectivity of immature life stages. | life-cycle studies were conducted on 2 molecular strains of mesocestoides tapeworms that represent different evolutionary lineages (clades a and b). wild carnivores, reptiles, and rodents were examined for tapeworm infections at 2 enzootic sites: (1) san miguel island (smi), a small island off the coast of southern california and (2) hopland research and extension center (hrec), a field station in northern california. results indicate that deer mice (peromyscus maniculatus) and coyotes (canis la ... | 2004 | 15040675 |
| relative roles of mutation and recombination in generating allelic polymorphism at an mhc class ii locus in peromyscus maniculatus. | the mhc class ii loci encoding cell surface antigens exhibit extremely high allelic polymorphism. there is considerable uncertainty in the literature over the relative roles of recombination and de novo mutation in generating this diversity. we studied class ii sequence diversity and allelic polymorphism in two populations of peromyscus maniculatus, which are among the most widespread and abundant mammals of north america. we find that intragenic recombination (or gene conversion) has been the p ... | 2003 | 14768893 |
| cloning and characterization of deer mouse (peromyscus maniculatus) cytokine and chemokine cdnas. | sin nombre virus (snv) establishes a persistent infection in the deer mouse, peromyscus maniculatus. a strong antibody response occurs in response to snv infection, but the role of the innate immune response is unclear. to address this issue, we have initiated an effort to identify and characterize deer mouse cytokine and chemokine genes. such cytokines and chemokines are involved in various aspects of immunity, including the transition from innate to adaptive responses, type i and type ii respo ... | 2004 | 14720307 |
| cold-acclimation in peromyscus: temporal effects and individual variation in maximum metabolism and ventilatory traits. | thermal acclimation in small endotherms provides an excellent model for the study of physiological plasticity, as energy requirements can be easily manipulated and the results are relevant for natural conditions. nevertheless, how physiology changes throughout acclimation, and how individuals vary in their response to acclimation, remain poorly understood. here we describe a high temporal-resolution study of cold acclimation in the deer mouse peromyscus maniculatus. the experimental design was b ... | 2004 | 14668313 |
| generation of a recombinant cytomegalovirus for expression of a hantavirus glycoprotein. | a cytomegalovirus (cmv) was isolated from its natural host, peromyscus maniculatus, and was designated peromyscus cmv (pcmv). a recombinant pcmv was constructed that contained sin nombre virus glycoprotein g1 (snv-g1) fused in frame to the enhanced green fluorescent protein (egfp) gene inserted into a site homologous to the human cmv ul33 (p33) gene. the recombinant cmv was used for expression and immunization of deer mice against snv-g1. the results of the study indicate that p. maniculatus cou ... | 2003 | 14581557 |
| maximal aerobic performance of deer mice in combined cold and exercise challenges. | in nature, animals frequently need to deal with several physiological challenges simultaneously. we examined thermoregulatory performance (body temperature stability) and maximal oxygen consumption of deer mice (peromyscus maniculatus) during intense exercise at room temperature, acute cold exposure, and exercise during cold exposure. results with exercise and cold exposure alone were consistent with previous studies: there was little difference between maximal metabolism elicited by exercise al ... | 2004 | 14569409 |
| effectiveness of six species of rodents as dispersers of singleleaf piñon pine (pinus monophylla). | the effectiveness of six species of rodents as dispersers of singleleaf piñon pine (pinus monophylla) was investigated in field enclosures. the rodent species were panamint kangaroo rat (dipodomys panamintinus), great basin pocket mouse (perognathus parvus), pinyon mouse (peromyscus truei), deer mouse (peromyscus maniculatus), least chipmunk (tamias minimus), and white-tailed antelope ground squirrel (ammospermophilus leucurus). five measures of seed harvesting and caching behavior were assessed ... | 2004 | 14534782 |
| autosomally determined polymorphism of glucose-6-phosphate dehydrogenase in peromyscus. | glucose-6-phosphate dehydrogenase commonly occurs in at least two forms in most tissues of the deer mouse, peromyscus maniculatus, as demonstrated by starch-gel electrophoresis. an autosomally determined genetic polymorphism in one of the enzymes was discovered. a hybrid molecule occurs in the heterozygote; this suggests a dimeric structure of this enzyme. | 1965 | 14289612 |
| bound and free corticosteroid in the plasma of two subspecies of deer mice (peromyscus maniculatus) after exposure to a low ambient temperature. | 1964 | 14231134 | |
| variation in the weight of the adrenal, pituitary and thyroid gland of the white-footed mouse, peromyscus maniculatus. | 1964 | 14109486 | |
| activity rhythm in peromyscus: its influence on rates of recovery from nembutal. | injection of sublethal doses of nembutal (sodium pentobarbital) into deer mice, peromyscus maniculatus rufinus (merriam), at diflerent times in their daily activity cycle revealed large differences in rates of recovery. by taking the phase of the circadian rhythm into account, the accuracy obtained in pharmaceutical and physiological bioassays could be increased. | 1963 | 14075704 |
| age of weaning in two subspecies of deer mice. | weaning age in deer mice is defined as the age at which the young mice maintain or gain weight during a 24-hour period of isolation; mice younger than weaning age lose weight. two subspecies of deer mice differed in weaning age; the age for peromyscus maniculatus bairdii was 18 days; for p. m. gracilis, 24 days. age and food consumption were better predictors of the weaning condition, as defined in terms of weight change with isolation, than body weight. | 1963 | 14032839 |
| separation of the public symphysis during pregnancy and after treatment with relaxin in two sub-species of peromyscus maniculatus. | 1961 | 14009892 | |
| the differential effects of chlorpromazine and pentobarbital on two forms of conditioned avoidance behavior in peromyscus maniculatus gracilis. | 1962 | 14001535 | |
| a comparison of body weight and thyroid gland activity in two subspecies of peromyscus maniculatus from birth to 70 days of age. | 1961 | 13889806 | |
| a gel diffusion analysis of saline-soluble antigens of two species of mice, peromyscus maniculatus and mus musculus. | 1961 | 13883683 | |
| factors concerned with the epizootiology of capillaria hepatica (bancroft, 1893) (nematoda) in a population of peromyscus maniculatus in algonquin park. canada. | 1960 | 13824755 | |
| effect of altitude on endurance running of peromyscus maniculatus. | 1961 | 13714810 | |
| definitive host relationships of the helminth parasites of the deer mouse, peromyscus maniculatus, in the bonneville basin of utah. | 1960 | 13709248 | |
| the isolation of leptospira hyos from a new host, peromyscus maniculatus. | 1959 | 13663566 | |
| the rearing of homozygous hairless deer mice, peromyscus maniculatus gambeli, with a note of superfetation or delayed fertilization. | 1959 | 13659440 | |
| effects of early handling upon adult behavior in two subspecies of deermice, peromyscus maniculatus. | 1959 | 13641470 | |
| histologic study of the skin of hairless american deer mice (peromyscus maniculatus gambeli). | 1957 | 13443615 | |
| vector competence of ixodes pacificus and i. spinipalpis (acari: ixodidae), and reservoir competence of the dusky-footed woodrat (neotoma fuscipes) and the deer mouse (peromyscus maniculatus), for borrelia bissettii. | we investigated the experimental vector competence of ixodes pacificus cooley and kohls and ixodes spinipalpis hadwen and nuttall, and the reservoir competence of the dusky-footed woodrat (neotoma fuscipes baird) and the deer mouse (peromyscus maniculatus [wagner]), for borrelia bissettii postic, marti ras, lane, hendson, and baranton. both rodent species are capable reservoirs for b. bissettii; infection rates for i. pacificus or i. spinipalpis nymphs fed as larvae on infected animals ranged fr ... | 2003 | 12943110 |
| analyses of gene flow among populations of deer mice (peromyscus maniculatus) at sites near hantavirus pulmonary syndrome case-patient residences. | gene flow and potential for sin nombre virus (snv) trafficking of the deer mouse (peromyscus maniculatus) was studied in delta and mesa counties of western colorado (usa). the study areas included grand mesa and surrounding grazing and agricultural areas. this area has several natural potential barriers to rodent gene flow, including rivers, cliffs, and mountains. ten study sites were utilized in a spatially nested design ranging from 0.65-81 km apart; four of these sites were at or near human h ... | 2003 | 12910755 |
| rapid and simple method for screening wild rodents for antibodies to sin nombre hantavirus. | sin nombre hantavirus (snv) is the primary etiologic agent of hantavirus cardiopulmonary syndrome (hcps) in the united states and canada. hantavirus cardiopulmonary syndrome is a zoonotic disease. the most common reservoir is the deer mouse (peromyscus maniculatus), although numerous other species of wild rodent can carry the viruses that cause hcps throughout the americas. infected rodents show no signs of clinical disease but they develop persistent infection. sin nombre virus can be contracte ... | 2003 | 12910753 |
| testicular histopathology in deer mice (peromyscus maniculatus) following exposure to polychlorinated biphenyl. | adult deer mice testes were subjected to routine histopathology following exposure to aroclor 1254 supplemented diet (5 ppm), for 30 days. body and testicular weight revealed no statistical significance between the control and treated animals. from a histological standpoint the testes of the controls were similar to normal murids and other animals. in contrast, the testes from treated animals displayed seminiferous tubules with significant degenerative alterations. these alterations included few ... | 2003 | 12729713 |
| spontaneous gallstone formation in deer mice: interaction of cholesterol, bile acids, and dietary fiber. | a study of the physiologic and ecologic factors involved in a spontaneous seasonal gallstone cycle of deer mice (peromyscus maniculatus gambelii) was conducted at the tulelake national wildlife refuge (california, usa) from march 1991 to june 1992. the specific hypothesis examined was whether or not seasonal increases in dietary fiber intake provides the necessary conditions for a solubility defect, or supersaturation mechanism, resulting in precipitation of cholesterol gallstones. results indic ... | 2003 | 12685073 |
| experimental evaluation of rodent exclusion methods to reduce hantavirus transmission to residents in a native american community in new mexico. | we conducted a pilot study to evaluate the efficacy of rodent proofing continuously occupied homes as a method for lowering the risk for hantavirus pulmonary syndrome (hps) among residents of a native american community in northwestern new mexico. rodent proofing of dwellings was paired with culturally appropriate health education. seventy homes were randomly assigned to treatment or control categories. treatment homes were rodent-proofed by sealing openings around foundations, doors, roofs, and ... | 2002 | 12653299 |
| marine resources subsidize insular rodent populations in the gulf of california, mexico. | inputs of energy and nutrients from one ecosystem may subsidize consumers in adjacent ones, with significant consequences for local communities and food webs. we used stable isotope and faecal pellet analysis to quantify use of ocean-derived resources by small mammals on islands in the gulf of california, mexico. rodents were live-trapped on grids originating near shore and extending 125-200 m inland to evaluate the extent to which rodents transport marine nutrients inland, and to determine whet ... | 2003 | 12647121 |
| age and aerobic performance in deer mice. | age impacts the phenotype of all multicellular animals, but lifetime changes in physiological traits are poorly understood for all but a few species. here, we describe a cross-sectional study of age effects on body composition, aerobic performance and ventilation in deer mice peromyscus maniculatus. this species lives considerably longer in captivity (in excess of 5 years) than most laboratory rodents, and the adaptational biology of its aerobic physiology is well studied. our deer mice grew thr ... | 2003 | 12604582 |
| hantavirus. | sin nombre virus (snv), an emerging pathogen in the united states, was identified in 1993. this hantavirus, a member of the bunyaviridae family of rna viruses, is transmitted by its reservoir host peromyscus maniculatus, the deer mouse. transmission is by inhalation of aerosolized feces, urine, or saliva from the infected mice. the illness that pursues, hantavirus pulmonary syndrome (hps), is characterized initially by mild flu-like symptoms, followed by rapid progression to respiratory distress ... | 2003 | 12587657 |
| bartonella strains from ground squirrels are identical to bartonella washoensis isolated from a human patient. | the most likely animal source of a human case of cardiac disease in washoe county, nev., was identified by comparison of dna sequences of three genes (citrate synthase glta, 60-kda heat shock protein gene groel, and 16s rrna gene) of bartonella washoensis cultured from the human patient in question and of bartonella isolates obtained from the following nevada rodents: peromyscus maniculatus (17 isolates), tamias minimus (11 isolates), spermophilus lateralis (3 isolates), and spermophilus beechey ... | 2003 | 12574261 |
| effects of in utero and lactational ammonium perchlorate exposure on thyroid gland histology and thyroid and sex hormones in developing deer mice (peromyscus maniculatus) through postnatal day 21. | thyroid gland hormone levels and histology and sex hormone levels in developing deer mice (peromyscus maniculatus) were measured following in utero and lactational exposure to ammonium perchlorate (ap), a component of rocket fuel and a thyroid toxicant. breeding pairs were dosed continuously with 0, 1 nm, 1 micro m, or 1 mm concentrations of ap in drinking water from the time of cohabitation until pups from the third litter were weaned. pups from the second litter were used for evaluation in thi ... | 2002 | 12515590 |