Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
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| strains of the propionibacterium acnes type iii lineage are associated with the skin condition progressive macular hypomelanosis. | progressive macular hypomelanosis (pmh) is a common skin disorder that causes hypopigmentation in a variety of skin types. although the underlying aetiology of this condition is unclear, there is circumstantial evidence that links the skin bacterium propionibacterium acnes to the condition. we now describe the first detailed population genetic analysis of p. acnes isolates recovered from paired lesional and non-lesional skin of pmh patients. our results demonstrate a strong statistical associati ... | 2016 | 27555369 |
| anti-acne, anti-dandruff and anti-breast cancer efficacy of green synthesised silver nanoparticles using coriandrum sativum leaf extract. | in this present investigation, agnps were green synthesised using coriandrum sativum leaf extract. the physicochemical properties of agnps were characterised using uv-visible spectrophotometer, field emission scanning microscopy/energy dispersive x-ray (fesem/edx), fourier transformed infrared spectroscopy (ft-ir), x-ray diffraction (xrd) and brunauer-emmett-teller (bet) analysis. further, in vitro anti-acne, anti-dandruff and anti-breast cancer efficacy of green synthesised agnps were assessed ... | 2016 | 27541567 |
| propionibacterium acnes overabundance and natural killer group 2 member d system activation in corpus-dominant lymphocytic gastritis. | corpus-dominant lymphocytic gastritis (lyg) is characterized by cd8(+) t-cell infiltration of the stomach epithelium by a so far uncharacterized mechanism. although helicobacter pylori is typically undetectable in lyg, patients respond to h. pylori antibiotic eradication therapy, suggesting a non-h. pylori microbial trigger for the disease. comparative microbiota analysis of specimens from lyg, h. pylori gastritis and healthy controls precluded involvement of h. pylori in lyg but identified prop ... | 2016 | 27538697 |
| prevalence of propionibacterium acnes in intervertebral discs of patients undergoing lumbar microdiscectomy: a prospective cross-sectional study. | the relationship between intervertebral disc degeneration and chronic infection by propionibacterium acnes is controversial with contradictory evidence available in the literature. previous studies investigating these relationships were under-powered and fraught with methodical differences; moreover, they have not taken into consideration p. acnes' ability to form biofilms or attempted to quantitate the bioburden with regard to determining bacterial counts/genome equivalents as criteria to diffe ... | 2016 | 27536784 |
| a novel 23s rrna mutation in propionibacterium acnes confers resistance to 14-membered macrolides. | 2016 | 27530860 | |
| [confusion over the term "contamination rate" as it pertains to blood cultures]. | the blood culture contamination rate is often used to validate specimen-collection procedures. cumitech has set its optimal target to be 2% to 3%. however, the term "contamination rate" has been defined in many ways, limiting its generalizability. the definitions used in earlier studies can be divided into two categories; definitions based on clinical judgements, and those based on preset rules. according to each principle, the equation must be composed of a defined numerator and denominator. th ... | 2016 | 27529972 |
| treatment modalities for acne. | acne is a common inflammatory skin disease which affects the pilosebaceous units of the skin. it can have severe psychological effects and can leave the patient with severe skin scarring. there are four well-recognized pathological factors responsible for acne which is also the target for acne therapy. in this review, different treatment options are discussed, including topical (i.e., retinoids, and antibiotics) and systemic (i.e., retinoids, antibiotics, and hormonal) treatments. since the gene ... | 2016 | 27529209 |
| incidence of propionibacterium acnes in initially culture-negative thioglycollate broths-a prospective cohort study at a danish university hospital. | the aim of this study was to prospectively investigate the incidence of propionibacterium acnes in thioglycollate broths reported as culture-negative at the department of clinical microbiology, rigshospitalet, to evaluate whether 5 days of incubation was enough to find all relevant cases. five hundred thioglycollate broths reported as culture-negative after 5 days were consecutively collected and incubated for at least a further 9 days (at least 14 days of incubation in total). only tissue sampl ... | 2016 | 27521804 |
| sequential antimicrobial treatment with linezolid for neurosurgical infections: efficacy, safety and cost study. | evidence for the effectiveness of linezolid in neurosurgical infections (nsis) is growing. the comfortable oral dosage and tolerance of linezolid opens the possibility for sequential antimicrobial treatment (sat) in stable patients after a period of intravenous treatment. | 2016 | 27520361 |
| factors shaping the composition of the cutaneous microbiota. | from birth, we are constantly exposed to bacteria, fungi and viruses, some of which are capable of transiently or permanently inhabiting our different body parts as our microbiota. the majority of our microbial interactions occur during and after birth, and several different factors, including age, sex, genetic constitution, environmental conditions and lifestyle, have been suggested to shape the composition of this microbial community. propionibacterium acnes is one of the most dominant lipophi ... | 2017 | 27518483 |
| draft genome sequence of highly rifampin-resistant propionibacterium namnetense nts 31307302t isolated from a patient with a bone infection. | propionibacterium namnetense was recently described as a potential bone pathogen, which is closely related to propionibacterium acnes, a skin commensal microorganism. here, we report the draft genome sequence of the highly rifampin-resistant strain nts 31307302(t) isolated from a patient with a tibia infection. | 2016 | 27516511 |
| evaluation of the antioxidative, antibacterial, and anti-inflammatory effects of the aloe fermentation supernatant containing lactobacillus plantarum hm218749.1. | little work is done to develop aloe vera (av) using probiotics. to explore the potential benefits, the antioxidant effects and the antibacterial effects on foodborne pathogens of aloe fermentation supernatant were evaluated in vitro. our results indicated that the aloe fermentation supernatant fermented by lactobacillus plantarum hm218749.1 had very strong scavenging capacities of the dpph (86%), o2 (•-) (85%), (•)oh (76%), and fe(2+) chelation (82%) and reducing powers (242.5 mg/l), and the inh ... | 2016 | 27493450 |
| the use of pcr/electrospray ionization-time-of-flight-mass spectrometry (pcr/esi-tof-ms) to detect bacterial and fungal colonization in healthy military service members. | the role of microbial colonization in disease is complex. novel molecular tools to detect colonization offer theoretical improvements over traditional methods. we evaluated pcr/electrospray ionization-time-of-flight-mass spectrometry (pcr/esi-tof-ms) as a screening tool to study colonization of healthy military service members. | 2016 | 27448413 |
| analysis of postoperative thoracolumbar spine infections in a prospective randomized controlled trial using the centers for disease control surgical site infection criteria. | wound infections following spinal surgery place a high toll on both the patient and the healthcare system. although several large series studies have examined the incidence and distribution of spinal wound infection, the applicability of these studies varies greatly since nearly every study is either retrospective and/or lacks standard inclusion criteria for defining surgical site infection. to address this void, we present results from prospectively gathered thoracolumbar spine surgery data for ... | 2016 | 27441172 |
| lung microbiome analysis in steroid-naїve asthma patients by using whole sputum. | although recent metagenomic approaches have characterized the distinguished microbial compositions in airways of asthmatics, these results did not reach a consensus due to the small sample size, non-standardization of specimens and medication status. we conducted a metagenomics approach by using terminal restriction fragment length polymorphism (t-rflp) analysis of the induced whole sputum representing both the cellular and fluid phases in a relative large number of steroid naïve asthmatics. | 2016 | 27433177 |
| heterogeneity and antibiotic resistance in propionibacterium acnes isolates and its therapeutic implications: blurring the lines between commensal and pathogenic phylotypes. | acne vulgaris is a multifactorial skin disease associated with the colonization of propionibacterium acnes. antibiotics are a mainstay of treatment for acne, yet the emergence of resistance against the currently approved antibiotics is a serious concern. in this case report, a slow responder had multiple propionibacterium acnes isolates with varied levels of sensitivity to the conventional antibiotics. the bacterial isolates obtained from acne samples collected from the patient were analyzed for ... | 2016 | 27424878 |
| propionibacterium acnes inhibits foxm1 and induces cell cycle alterations in human primary prostate cells. | propionibacterium acnes has been detected in diseased human prostate tissue, and cell culture experiments suggest that the bacterium can establish a low-grade inflammation. here, we investigated its impact on human primary prostate epithelial cells. microarray analysis confirmed the inflammation-inducing capability of p. acnes but also showed deregulation of genes involved in the cell cycle. qpcr experiments showed that viable p. acnes downregulates a master regulator of cell cycle progression, ... | 2016 | 27424770 |
| drug eruption secondary to vancomycin-laden spacer in the shoulder: a case report. | 2016 | 27422463 | |
| effects of 5-aminolevulinic acid photodynamic therapy on tlrs in acne lesions and keratinocytes co-cultured with p. acnes. | to investigate the effect of 5-aminolevulinic acid photodynamic therapy (ala-pdt) on the expression of toll like receptors (tlrs) in human keratinocytes and its role in acne treatment. | 2016 | 27421917 |
| recent progress in the research about propionibacterium acnes strain diversity and acne: pathogen or bystander? | recent progress has steadily reported the existence of the diverse strains of propionibacterium acnes, and these studies have contributed to the elucidation of their contradictory roles between normal commensals and pathogens. in this review, the authors aimed to provide an update on the recent understanding of research about p. acnes strain diversity and acne, analyzing the potential implications for clinical applications. before the era of genomic research, p. acnes was known to be distinguish ... | 2016 | 27421121 |
| antibiotic-resistant acne: getting under the skin. | propionibacterium acnes is a key pathogenic factor in the development of acne. antibiotics are the first choice of treatment for mild-to-moderate, mixed, papular/pustular, and moderate nodular acne, and an alternative choice in severe, nodular/conglobate acne. the emergence of resistance to the currently available antibiotics poses a serious set-back to this algorithm, and the reduced arsenal can diminish efficacy of treatment. this emerging situation should catalyze innovations in dermatology; ... | 2016 | 27416310 |
| topical and oral antibiotics for acne vulgaris. | antibiotics, both oral and topical, have been an integral component of the management of acne vulgaris (av) for approximately 6 decades. originally thought to be effective for av due to their ability to inhibit proliferation of propionibacterium acnes, it is now believed that at least some antibiotics also exert anti-inflammatory effects that provide additional therapeutic benefit. to add, an increase in strains of p acnes and other exposed bacteria that are less sensitive to antibiotics used to ... | 2016 | 27416309 |
| glove contamination during endodontic treatment is one of the sources of nosocomial endodontic propionibacterium acnes infections. | the opportunistic propionibacterium acnes recovered frequently from failed endodontic treatments might be the result of nosocomial endodontic infections. the study was aimed to determine if gloves worn by dentists could be one of the sources of these nosocomial infections and to investigate the p. acnes phylotypes involved. | 2016 | 27395473 |
| in vitro evaluation of bioactive potential of bacillus methylotrophicus yml008 against propionibacterium acnes. | acne vulgaris is the most common skin diseases that people experience during their lives. thirteen rhizosphere isolates were screened against propionibacterium acnes. the bacterium exhibited the highest activity against p. acnes was identified as bacillus methylotrophicus yml008 by 16s rrna gene sequencing. scanning electron microscopy was used to assess the changes in morphology of p. acnes. preliminary studies on the antimicrobial substance demonstrated the hydrophilic nature of compound with ... | 2016 | 27383487 |
| thoracic aortic graft infections secondary to propionibacterium species: two cases and review of the literature. | aortic graft infections are a rare occurrence, most commonly secondary to gram-positive organisms (staphylococcus and streptococcus species). we present 2 cases of thoracic aortic graft infections secondary to anaerobic bacteria, propionibacterium species. the first case, a 40-year-old male, was found to have an anastomotic aneurysm at the distal anastomosis of a previous thoracoabdominal aneurysm repair. during the open repair of his anastomotic aneurysm, the original graft was not incorporated ... | 2016 | 27381316 |
| different propionibacterium acnes phylotypes induce distinct immune responses and express unique surface and secreted proteomes. | propionibacterium acnes is a skin commensal bacterium that contributes to the development of acne vulgaris and other infections. recent work revealed that p. acnes clinical isolates can be classified into distinct phylotypes, several of which have associations with healthy skin or acne. we sought to determine if these phylotypes induce different immunological responses and express protein factors that may contribute to their disease associations. we found that acne-associated p. acnes phylotypes ... | 2016 | 27377696 |
| antimicrobial activity of sebocytes against propionibacterium acnes via toll-like receptor 2 and lysosomal pathway. | 2016 | 27375109 | |
| propionibacterium avidum as an etiological agent of prosthetic hip joint infection. | propionibacterium acnes is well-established as a possible etiologic agent of prosthetic joint infections (pjis). other propionibacterium spp. have occasionally been described as a cause of pjis, but this has not previously been the case for p. avidum despite its capacity to form biofilm. we describe two patients with prosthetic hip joint infections caused by p. avidum. both patients were primarily operated with an anteriorly curved skin incision close to the skin crease of the groin, and both we ... | 2016 | 27355425 |
| infections following arthroscopic rotator cuff repair: incidence, risk factors, and prophylaxis. | the primary aim of the present study was to determine the incidence of infections following arthroscopic rotator cuff repair in a single department over a 10-year period. secondary goals included the evaluation of potential risk factors for infections and to investigate the efficacy of perioperative antibiotic prophylaxis in the reduction of infectious complications. | 2017 | 27342982 |
| erratum to: frequency and typing of propionibacterium acnes in prostate tissue obtained from men with and without prostate cancer. | [this corrects the article doi: 10.1186/s13027-016-0074-9.]. | 2016 | 27335583 |
| inhibitory effects of schisandra chinensis extract on acne-related inflammation and uvb-induced photoageing. | schisandra chinensis (turcz.) baill. (schisandraceae) fruit extract (sfe) has been reported to induce non-specific tissue protection against inflammation in vivo. however, the effects of sfe on propionibacterium acnes-stimulated acne and uvb-irradiated photoageing have yet to be investigated. | 2016 | 27328727 |
| ereply. towards better understanding and management of propionibacterium acnes in cases of prosthetic valve endocarditis. | 2016 | 27325659 | |
| ecomment. towards better understanding and management of propionibacterium acnes in cases of prosthetic valve endocarditis. | 2016 | 27325658 | |
| saddle nose with sarcoidosis: "a great imitator" of relapsing polychondritis. | sarcoidosis is a systemic granulomatous disease that can affect any organ including the nose. nasal crusting and congestion are common nasal symptoms of sarcoidosis, whereas cases of saddle-nose deformity are rarely reported. we describe here a case of sarcoidosis that presented with saddle nose resembling relapsing polychondritis. since sarcoidosis shares clinical features with relapsing polychondritis, the differential diagnosis of saddle nose can be challenging without a clear pathology. | 2016 | 27321667 |
| is it time to switch on or off the green light for ultraviolet-induced red fluorescence as a surrogate marker for propionibacterium acnes in vivo? | 2017 | 27307204 | |
| the use of oral antibiotics in treating acne vulgaris: a new approach. | although acne is not an infectious disease, oral antibiotics have remained a mainstay of treatment over the last 40 years. the anti-inflammatory properties of oral antibiotics, particularly the tetracyclines, are efficacious in treating inflammatory acne lesions. common prescribing practices in dermatology exert significant selection pressure on bacteria, contributing to the development of antibiotic resistance. antibiotic use for acne not only promotes resistance in propionibacterium acnes, but ... | 2016 | 27306750 |
| epidemiology of deep surgical site infections after pediatric spinal fusion surgery. | single-institution, retrospective case series. | 2017 | 27306257 |
| antimicrobial activities of ozenoxacin against isolates of propionibacteria and staphylococci from japanese patients with acne vulgaris. | ozenoxacin, a novel non-fluorinated topical quinolone, was assessed for in vitro antimicrobial activity against clinical isolates of propionibacteria and staphylococci according to the broth microdilution method recommended by the clinical and laboratory standards institute. the isolates used in this study were collected from japanese patients with acne vulgaris during a period from 2012 to 2013. the mic90s of ozenoxacin against propionibacterium acnes (n=266), propionibacterium granulosum (n=10 ... | 2016 | 27305898 |
| strain-level differences in porphyrin production and regulation in propionibacterium acnes elucidate disease associations. | propionibacterium acnes is an important skin commensal, but it is also considered a pathogenic factor in several diseases including acne vulgaris, the most common skin disease. while previous studies have revealed p. acnes strain-level differences in health and disease associations, the underlying molecular mechanisms remain unknown. recently, we demonstrated that vitamin b12 supplementation increases p. acnes production of porphyrins, a group of proinflammatory metabolites important in acne dev ... | 2017 | 27303708 |
| frequency and typing of propionibacterium acnes in prostate tissue obtained from men with and without prostate cancer. | prostate cancer is the most common cancer among men in western countries but the exact pathogenic mechanism of the disease is still largely unknown. an infectious etiology and infection-induced inflammation has been suggested to play a role in prostate carcinogenesis and propionibacterium acnes has been reported as the most prevalent microorganism in prostatic tissue. we investigated the frequency and types of p. acnes isolated from prostate tissue samples from men with prostate cancer and from ... | 2016 | 27284286 |
| endocarditis in patients with ascending aortic prosthetic graft: a case series from a national multicentre registry. | endocarditis in patients with ascending aortic prosthetic graft (aapg) is a life-threatening complication. the purpose of this study was to examine the clinical presentation and prognosis of patients with aapg endocarditis included in a large prospective infectious endocarditis multicentre study. | 2016 | 27283156 |
| synovitis, acne, pustulosis, hyperostosis, and osteitis (sapho) syndrome - a challenging diagnosis not to be missed. | sapho syndrome manifests as chronic inflammation of bones and joints, which may or may not be accompanied by skin changes. the term sapho is an acronym that stands for synovitis, acne, pustulosis (usually palmoplantar), hyperostosis and osteitis. the bones most commonly affected are those in the anterior chest wall (mainly the sternum, clavicles and sternocostoclavicular joints), the vertebrae and the sacroiliac joints, but peripheral and flat bones may also be involved, especially in children. ... | 2016 | 27263075 |
| propionibacterium namnetense sp. nov., isolated from a human bone infection. | a polyphasic taxonomic study was performed on two gram-positive-staining, anaerobic, pleomorphic, rod-shaped strains isolated from human bone and tissue samples. sequencing of the 16s rrna genes revealed that the strains belong to a novel species within the genus propionibacterium, most closely related to propionibacterium acnes subsp. acnes and propionibacterium acnes subsp. elongatum with similarity values of 98.4 % and 98.1 %, respectively. in addition, protein-coding genes for rpob, reca and ... | 2016 | 27259292 |
| propionibacterium acnes biofilm - a sanctuary for staphylococcus aureus? | the purpose of this study was to measure the effect of combined culture of propionibacterium acnes and staphylococcus aureus on biofilm formation under different oxygen concentrations. we measured planktonic growth and biofilm formation of p. acnes and s. aureus alone and together under aerobic and anaerobic conditions. both p. acnes and s. aureus grew under anaerobic conditions. when grown under anaerobic conditions, p. acnes with or without s. aureus formed a denser biomass biofilm than did s. ... | 2016 | 27241780 |
| unusual acute onset of abdominal aortic endograft infection by propionibacterium acnes after coil embolization for type ii endoleak. | propionibacterium acnes, an anaerobic gram-positive bacillus that inhabits the skin, has rarely been incriminated in abdominal aortic endograft infection. it is usually responsible for typical delayed and low-grade postoperative infections. we report the case of a 66-year-old patient who developed acute p. acnes aortic stent-graft infection 9 days after percutaneous embolization for type ii endoleak. the stent graft had been implanted 2 years before. because of persistent signs of sepsis and dis ... | 2016 | 27238987 |
| propionibacterium acnes induces an adjuvant effect in b-1 cells and affects their phagocyte differentiation via a tlr2-mediated mechanism. | b-1 lymphocytes are present in large numbers in the mouse peritoneal cavity, as are macrophages, and are responsible for natural igm production. these lymphocytes migrate to inflammatory foci and are also involved in innate immunity. it was also demonstrated that b-1 cells are able to differentiated into phagocytes (b-1cdp), which is characterized by expression of f4/80 and increased phagocytic activity. b-1 cell responses to antigens and adjuvants are poorly characterized. it has been shown tha ... | 2016 | 27233619 |
| assessment of anaerobic blood cultures in pediatric oncology patients. | the routine use of a single aerobic bottle for blood culture in pediatric patients has become commonplace, as anaerobic bacteria are not frequently involved in clinically significant infections. the aim of this study was to assess the usefulness of routinely performing anaerobic blood cultures in pediatric oncology patients. | 2017 | 27221161 |
| bilateral sequential propionibacterium acnes exogenous endophthalmitis. | a 68-year-old man underwent uncomplicated sequential cataract extractions performed more than a year apart. he presented 6 months after the second surgery with persistent intraocular inflammation in both eyes. cultures from both eyes grew propionibacterium acnes and he responded well to treatment. suspicion for delayed-onset post-operative endophthalmitis must remain high in uveitis cases that fail to resolve with anti-inflammatory treatments. the authors believe this is the first reported case ... | 2016 | 27220771 |
| autophagy induced by intracellular infection of propionibacterium acnes. | sarcoidosis is caused by th1-type immune responses to unknown agents, and is linked to the infectious agent propionibacterium acnes. many strains of p. acnes isolated from sarcoid lesions cause intracellular infection and autophagy may contribute to the pathogenesis of sarcoidosis. we examined whether p. acnes induces autophagy. | 2016 | 27219015 |
| clinical features of infectious keratitis caused by propionibacterium acnes. | propionibacterium acnes is a commensal bacteria whose pathogenicity in infectious keratitis is unclear. in this study, we report infectious keratitis cultured with p. acnes and evaluate its clinical characteristics. | 2016 | 27203796 |
| pulmonary fibrosis in a mouse model of sarcoid granulomatosis induced by booster challenge with propionibacterium acnes. | pulmonary fibrosis (pf) associated with chronic sarcoidosis remains poorly understood, and no experimental model is currently available for this condition. previous studies have shown that propionibacterium acnes (pa) was associated with sarcoidosis and induced granuloma formation in mice. here, we investigated whether repeated challenge with pa induces persistent inflammation leading to sarcoidosis followed by pf in mice. specifically, c57bl/6 mice were inoculated intraperitoneally and subjecte ... | 2016 | 27203210 |
| first cultivation of health-associated tannerella sp. hot-286 (bu063). | despite significant advances in recent years in culture-independent molecular microbiology methods, the detailed study of individual bacterial species still relies on having pure cultures in the laboratory. yet, more than a third of the approximately 700 bacterial taxa found in the human oral cavity are as yet uncultivated in vitro. one such taxon, tannerella sp. hot-286 (phylotype bu063), is the focus of much interest since it is associated with periodontal health, while tannerella forsythia, i ... | 2016 | 27193146 |
| inhibition of propionibacterium acnes associated biofilm formation by decanediol. | 2016 | 27188522 | |
| comparison effect of azithromycin gel 2% with clindamycin gel 1% in patients with acne. | acne vulgaris is the most common skin disease. local and systemic antimicrobial drugs are used for its treatment. but increasing resistance of propionibacterium acnes to antibiotics has been reported. | 2016 | 27169103 |
| nasal and conjunctival screening prior to refractive surgery: an observational and cross-sectional study. | to investigate bacterial flora of clinically healthy conjunctiva and nasal cavity among patients prior to refractive surgery, as well as the characteristics of patients with methicillin-resistant staphylococcus aureus (mrsa) colonisation. | 2016 | 27160843 |
| osteomyelitis of the humerus caused by propionibacterium acnes. | propionibacterium acnes is a fastidious slow-growing anaerobic gram-positive bacillus best known for causing acne. however, it only occasionally has been isolated from invasive infections. in that setting, slow growth and low virulence may lead to indolent presentations and diagnostic delays as illustrated by the following case. | 2016 | 27159477 |
| influence of a polymerizable eugenol derivative on the antibacterial activity and wettability of a resin composite for intracanal post cementation and core build-up restoration. | eugenol has been used in dentistry due to its ability to inhibit the growth of a range of microorganisms, including facultative anaerobes commonly isolated from infected root canals. the aim of this study was to evaluate the antibacterial activity of the experimental composites containing eugenyl methacrylate monomer (egma), a polymeric derivative of eugenol, against a range of oral bacteria, commonly associated with failure of coronal and endodontic restorations. in vitro composite behavior and ... | 2016 | 27130610 |
| quantification of the antibody response to propionibacterium acnes in a patient with prosthetic valve endocarditis: - a case report. | the isolation of propionibacterium acnes in blood cultures is often considered a contaminant. on rare occasions, p. acnes can cause severe infections, including endocarditis and intravascular prosthesis-associated infections. to evaluate the discrimination between a contaminant and a clinically relevant infection we used an ouchterlony test system to quantify the antibody response to p. acnes in a patient with a proven p. acnes endocarditis. | 2016 | 27126586 |
| absence or low density of propionibacterium acnes in comedonal lesions of acne patients? a surface to inside study of skin fluorescence. | 2016 | 27125260 | |
| microbiota of an italian grana-like cheese during manufacture and ripening, unraveled by 16s rrna-based approaches. | the microbial ecology of cheese involves a rich and complex interaction between starter lactic acid bacteria and nonstarter lactic acid bacteria (nslab), mainly originating from raw milk and/or from the environment, that can contribute to the final characteristics of cheese. the aim of the present research was the exploration of the active microbiota by rna-based approaches during the manufacturing and ripening of a grana-like cheese. reverse transcriptase pcr (rt-pcr)-denaturing gradient gel el ... | 2016 | 27107125 |
| propionibacterium acnes infected intervertebral discs cause vertebral bone marrow lesions consistent with modic changes. | modic type i change (mc1) are vertebral bone marrow lesions adjacent to degenerated discs that are specific for discogenic low back pain. the etiopathogenesis is unknown, but occult discitis, in particular with propionibacteria acnes (p. acnes), has been suggested as a possible etiology. if true, antibiotic therapy should be considered for patients with mc1. however, this hypothesis is controversial. while some studies report up to 40% infection rate in herniated discs, others fail to detect inf ... | 2016 | 27101067 |
| a silent ghost in the right atrium. | 2016 | 27082775 | |
| efficacy of red or infrared light-emitting diodes in a mouse model of propionibacterium acnes-induced inflammation. | laser/light-based devices may provide an alternative to conventional acne therapeutics in some patients with nonresponsive acne. | 2016 | 27081265 |
| direct electrical current reduces bacterial and yeast biofilm formation. | new strategies are needed for prevention of biofilm formation. we have previously shown that 24 hr of 2,000 µa of direct current (dc) reduces staphylococcus epidermidis biofilm formation in vitro. herein, we examined the effect of a lower amount of dc exposure on s. epidermidis, staphylococcus aureus, escherichia coli, pseudomonas aeruginosa, propionibacterium acnes, and candida albicans biofilm formation. 12 hr of 500 µa dc decreased s. epidermidis, s. aureus, e. coli, and p. aeruginosa biofilm ... | 2016 | 27073807 |
| pulmonary mucosa-associated lymphoid tissue lymphoma associated with pulmonary sarcoidosis: a case report and literature review. | differentiating low-grade lymphoma from preexisting sarcoidosis is difficult because of their pathological similarity. this article describes a case of pulmonary mucosa-associated lymphoid tissue lymphoma associated with pulmonary sarcoidosis. the patient, a 45-year-old japanese man, presented with a 10-year history of pulmonary sarcoidosis and 5-year history of ocular sarcoidosis with histologic findings. because only the right s3 lung nodule had gradually enlarged, partial resection was perfor ... | 2016 | 27067783 |
| prosthetic valve endocarditis due to propionibacterium acnes. | to study the characteristics of patients with propionibacterium acnes prosthetic valve endocarditis (pve) who required surgery. | 2016 | 27052748 |
| which is the best treatment for prosthetic joint infections due to propionibacterium acnes: need for further biofilm in vitro and experimental foreign-body in vivo studies? | 2016 | 27045190 | |
| zolav(®) (a p-carboethoxy-tristyrylbenzene derivative) [corrected]: a new antibiotic for the treatment of acne. | acne is a prominent skin condition affecting >80% of teenagers and young adults and ~650 million people globally. isotretinoin, a vitamin a derivative, is currently the standard of care for treatment. however, it has a well-established teratogenic activity, a reason for the development of novel and low-risk treatment options for acne. | 2016 | 27042015 |
| the challenge of propionibacterium acnes and revision shoulder arthroplasty: a review of current diagnostic options. | propionibacterium acnes is the most common cause of infection after shoulder arthroplasty. whereas there are several methods that can aid in the diagnosis of p. acnes infection, there is not a single "gold standard" because of the difficulties inherent in identifying this bacterium. we present an evidence-based discussion of the demographic, clinical, and radiographic predictors of p. acnes infection and review the current options for diagnosis. | 2016 | 27038565 |
| clinical analysis of propionibacterium acnes infection after total knee arthroplasty. | propionibacterium acnes is a common cause of upper extremity arthroplasty infection and usually presents in an indolent subacute fashion. it is not well described how total knee arthroplasty (tka) patients infected with p acnes present. | 2016 | 27036925 |
| gut microbiota profiling of pediatric nonalcoholic fatty liver disease and obese patients unveiled by an integrated meta-omics-based approach. | there is evidence that nonalcoholic fatty liver disease (nafld) is affected by gut microbiota. therefore, we investigated its modifications in pediatric nafld patients using targeted metagenomics and metabolomics. stools were collected from 61 consecutive patients diagnosed with nonalcoholic fatty liver (nafl), nonalcoholic steatohepatitis (nash), or obesity and 54 healthy controls (ctrls), matched in a case-control fashion. operational taxonomic units were pyrosequenced targeting 16s ribosomal ... | 2017 | 27028797 |
| microbiologic profile of infections in presumed aseptic revision spine surgery. | intra-operative cultures may be obtained in revision spine surgery despite the absence of pre-operative clinical markers of infection. the microbiologic profile of culture positive cases in which there is no clear evidence of infection preoperatively has not been described. the aim of this investigation is to report on the microbiologic profile of unexpected culture positive revision spine surgery cases. | 2016 | 27026016 |
| propionibacterium prosthetic joint infection: experience from a retrospective database analysis. | with improved diagnostic methods and longer prosthesis indwelling time, the frequency of diagnosed propionibacterium prosthetic joint infections (pji) is increasing. data on clinical, microbiological, radiological and surgical treatment are limited, and importance of this organism in pji is probably underestimated. | 2016 | 27017334 |
| physical modalities (devices) in the management of acne. | treatment options for acne vulgaris are enhanced by laser and light therapy. both visible and laser light are effective treatments for acne. visible light and many lasers target propionibacterium acnes porphyrins while others act as anti-inflammatory mediators or reduce sebaceous gland activity. compared with topical and systemic therapies, laser and light therapies have few if any side effects and appear to be safe during pregnancy. if patients prefer at home light treatments, several devices a ... | 2016 | 27015782 |
| the clinical relevance of antibiotic resistance: thirteen principles that every dermatologist needs to consider when prescribing antibiotic therapy. | antibiotics are commonly used by dermatologists in clinical practice, primarily because of the overall track record of favorable efficacy and safety with the most commonly used agents. during the past decade, increased attention has been given to the problems associated with antibiotic resistance. this article summarizes important principles gleaned from the continued efforts of the scientific panel on antibiotic use in dermatology; other groups working diligently in this area, such as the cente ... | 2016 | 27015776 |
| the relationship of proper skin cleansing to pathophysiology, clinical benefits, and the concomitant use of prescription topical therapies in patients with acne vulgaris. | patients often perceive the cause of their acne to be related to a lack of proper cleansing, therefore many patients attempt to treat their acne either alone or with prescription therapy by frequent aggressive cleansing with harsh cleansing agents. altered epidermal barrier function, inflammation, and propionibacterium acnes are related to acne vulgaris (av) pathophysiology; proper cleansing can favorably modulate the development of av. the available clinical studies support gentle cleansing in ... | 2016 | 27015773 |
| outcomes in the treatment of periprosthetic joint infection after shoulder arthroplasty: a systematic review. | although many case series have been published on the treatment of shoulder periprosthetic joint infection (pji), few provide direct comparison of outcomes. this systematic review synthesizes the available english literature on shoulder pji to quantify treatment effectiveness. | 2016 | 27012542 |
| propionibacterium acnes brain abscess in an immunocompetent man in the absence of prior neurosurgery. | propionibacterium acnes is a rare, but established, cause of intracranial abscesses. we describe a case of p. acnes brain abscess in an immunocompetent man without prior neurosurgery. a 49-year old man with mild psoriasis presented with a two-week history of gait changes, generalized weakness and a two-day history of headaches, aphasia and confusion. imaging revealed a left thalamic mass and surgical biopsy suggested a pyogenic abscess. cultures of biopsy samples of the abscess grew p. acnes alo ... | 2016 | 26999913 |
| [bacterial vaginosis: efficacy of a local treatment with a gel containing a fraction derived from propinibacterium acnes]. | bacterial vaginosis (bv) is favored by a decreased activity of vaginal immune system. the fraction derived from propionibacterium acnes is known to activate the immune system and is used parenterally to treat respiratory and urinary infections. the employ of a fraction derived from propionibacterium acnes locally, in the context of the vaginal immune system, is made possible by a vaginal gel in which this fraction is associated with hyaluronic acid, well-known for its moisturizing activity, and ... | 2016 | 26990097 |
| an in vitro model for bacterial growth on human stratum corneum. | the diversity and dynamics of the skin microbiome in health and disease have been studied recently, but adequate model systems to study skin microbiotas in vitro are largely lacking. we developed an in vitro system that mimics human stratum corneum, using human callus as substrate and nutrient source for bacterial growth. the growth of several commensal and pathogenic bacterial strains was measured for up to one week by counting colony-forming units or by quantitative pcr with strain-specific pr ... | 2016 | 26976779 |
| discovery of a novel seminal fluid microbiome and influence of estrogen receptor alpha genetic status. | bacteria harbored in the male reproductive system may influence reproductive function and health of the male and result in developmental origins of adult health and disease (dohad) effects in his offspring. such effects could be due to the seminal fluid, which is slightly basic and enriched with carbohydrates; thereby, creating an ideal habitat for microbes or a potential seminal fluid microbiome (sfm). using wild-type (wt) and estrogen receptor-alpha (esr1) knockout (ko) male mice, we describe ... | 2016 | 26971397 |
| a myrtus communis extract enriched in myrtucummulones and ursolic acid reduces resistance of propionibacterium acnes biofilms to antibiotics used in acne vulgaris. | recent works present evidence of propionibacterium acnes growing as a biofilm in cutaneous follicles. this formation of clusters is now considered as an explanation for the in vivo resistance of p. acnes to the main antimicrobials prescribed in acne vulgaris. | 2016 | 26969384 |
| the formulation of bacteriophage in a semi solid preparation for control of propionibacterium acnes growth. | to isolate and characterise phage which could lyse p. acnes and to formulate the phage into a delivery form for potential application in topical treatment of acne infection. | 2016 | 26964063 |
| choline and geranate deep eutectic solvent as a broad-spectrum antiseptic agent for preventive and therapeutic applications. | antiseptic agents are the primary arsenal to disinfect skin and prevent pathogens spreading within the host as well as into the surroundings; however the food and drug administration published a report in 2015 requiring additional validation of nearly all current antiseptic agents before their continued use can be allowed. this vulnerable position calls for urgent identification of novel antiseptic agents. recently, the ability of a deep eutectic, choline and geranate (cage), to treat biofilms o ... | 2016 | 26959835 |
| dilemmas surrounding the diagnosis of deep brain stimulation electrode infection without associated wound complications: a series of two cases. | when wounds are benign, diagnosis of deep brain stimulation (dbs) electrode infection and associated intraparenchymal infection can be challenging. only a couple, such cases exist in literature. since infections of the central nervous system can be life-threatening, prompt diagnosis is necessary to prevent neurological injury. employed within the appropriate context, magnetic resonance imaging (mri) of the brain, as well as laboratory data and clinical presentation, may help guide diagnosis. | 2016 | 26958428 |
| cross-sectional pilot study of antibiotic resistance in propionibacterium acnes strains in indian acne patients using 16s-rna polymerase chain reaction: a comparison among treatment modalities including antibiotics, benzoyl peroxide, and isotretinoin. | antibiotic resistance is a worldwide problem in acne patients due to regional prescription practices, patient compliance, and genomic variability in propionibacterium acnes, though the effect of treatment on the resistance has not been comprehensively analyzed. | 2017 | 26955094 |
| evaluation of anti-microbial activities of zno, citric acid and a mixture of both against propionibacterium acnes. | in this study, anti-microbial activities of zno of three different particle sizes of citric acid (ca) and of mixtures of zno and ca were confirmed against propionibacterium acnes. | 2016 | 26940755 |
| characteristics and treatment outcomes of propionibacterium acnes prosthetic shoulder infections in adults. | background. prosthetic joint infections (pjis) significantly complicate joint arthroplasties. propionibacterium acnes is an increasingly recognized pji pathogen, yet limited clinical and therapeutic data exist. we sought to examine characteristics of p. acnes shoulder pjis and compare surgical and nonsurgical management outcomes. methods. a retrospective analysis of p. acnes shoulder pjis was conducted at an academic center in baltimore, maryland from 2000 to 2013. results. of 24 cases of p. ... | 2016 | 26933665 |
| a combination of ellagic acid and tetracycline inhibits biofilm formation and the associated virulence of propionibacterium acnes in vitro and in vivo. | propionibacterium acnes is an opportunistic pathogen which has become notorious owing to its ability to form a recalcitrant biofilm and to develop drug resistance. the current study aimed to develop anti-biofilm treatments against clinical isolates of p. acnes under in vitro and in vivo conditions. a combination of ellagic acid and tetracycline (etc; 250 μg ml(-1) + 0.312 μg ml(-1)) was determined to effectively inhibit biofilm formation by p. acnes (80-91%) without affecting its growth, therefo ... | 2016 | 26930280 |
| modic changes and disc degeneration caused by inoculation of propionibacterium acnes inside intervertebral discs of rabbits: a pilot study. | to investigate whether p. acnes could induce disc degeneration and modic changes when inoculated into the discs of rabbits. | 2016 | 26925420 |
| antagonism between staphylococcus epidermidis and propionibacterium acnes and its genomic basis. | propionibacterium acnes and staphylococcus epidermidis live in close proximity on human skin, and both bacterial species can be isolated from normal and acne vulgaris-affected skin sites. the antagonistic interactions between the two species are poorly understood, as well as the potential significance of bacterial interferences for the skin microbiota. here, we performed simultaneous antagonism assays to detect inhibitory activities between multiple isolates of the two species. selected strains ... | 2016 | 26924200 |
| the role of topical dermocosmetics in acne vulgaris. | acne is a common chronic inflammatory disease and treatment modalities based on acne severity are well established. the role of dermocosmetics in dermatology, and in particular acne, is becoming more important as more research elucidates the mechanisms of action of products in the pathogenesis of acne. dermocosmetics have the potential to be used as monotherapy or in combination with medical treatment. therefore, it has become important for dermatologists to understand dermocosmetics to effectiv ... | 2016 | 26916232 |
| hyaluronidase in clinical isolates of propionibacterium acnes. | objectives. we sought to describe the prevalence of a hyaluronidase gene and hyaluronidase production in 197 clinical isolates of p. acnes; we assessed kinetics of hyaluronidase production in a subset of three isolates. methods. the hyaluronidase gene was detected using polymerase chain reaction. hyaluronidase production was detected by growing isolates on bhi agar containing 400 μg/ml hyaluronic acid and 1% albumin and flooding plates with 2 n glacial acetic acid to precipitate unbound hyaluron ... | 2015 | 26904745 |
| a rare case of delayed onset capsular block syndrome managed using 25-gauge vitrector. | we report a case of delayed onset capsular block syndrome in a patient 6 years after undergoing cataract surgery. ocular examination revealed marked diminution of vision accompanied with a collection of milky fluid between the intraocular lens and posterior capsule. to treat and to understand the pathology of the condition, aspiration of fluid using 25-gauge vitrector through pars plana was done, and contents sent for microbiological analysis which did not reveal any growth. postoperative period ... | 2017 | 26903727 |
| staphylococcus epidermidis sets things right again. | commensal cutaneous bacteria are believed to play a role in skin homeostasis, possibly by counteracting the effects of pathogenic inflammation. in this issue, xia et al. show that staphylococcus epidermidis is involved in the regulation of propionibacterium acnes-induced inflammation. staphylococcal lipoteichoic acid induces mir-143, which in turn inhibits toll-like receptor 2 mrna to decrease toll-like receptor 2 protein and consequently suppresses p. acnes-induced proinflammatory cytokines. | 2016 | 26902125 |
| guidelines of care for the management of acne vulgaris. | acne is one of the most common disorders treated by dermatologists and other health care providers. while it most often affects adolescents, it is not uncommon in adults and can also be seen in children. this evidence-based guideline addresses important clinical questions that arise in its management. issues from grading of acne to the topical and systemic management of the disease are reviewed. suggestions on use are provided based on available evidence. | 2016 | 26897386 |
| high-throughput sequencing of cerebrospinal fluid for diagnosis of chronic propionibacterium acnes meningitis in an allogeneic stem cell transplant recipient. | a 40-year-old man with chronic myelogenous leukemia presented multiple times over a period of 3 years with episodes of confusion, wide-based gait and falls because of recurrent hydrocephalus despite repeated therapeutic lumbar punctures. these problems occurred in the context of persistent cerebrospinal fluid (csf) pleocytosis and leptomeningeal enhancement. extensive diagnostic workups and therapeutic trials had failed to identify a clinically plausible cause or produce any significant improvem ... | 2016 | 26895706 |
| glycerol monolaurate inhibits lipase production by clinical ocular isolates without affecting bacterial cell viability. | we sought to determine the relative lipase production of a range of ocular bacterial isolates and to assess the efficacy of glycerol monolaurate (gml) in inhibiting this lipase production in high lipase-producing bacteria without affecting bacterial cell growth. | 2016 | 26873514 |
| the bacterial microbiome in chronic rhinosinusitis: richness, diversity, postoperative changes, and patient outcomes. | the bacterial microbiome in chronic rhinosinusitis (crs) remains poorly understood. microorganisms are believed to be important contributors to the inflammatory response seen in these patients. | 2016 | 26867528 |
| do sublaminar polyester bands affect the outcomes of postoperative infections after adolescent idiopathic scoliosis surgery? | the incidence of surgical site infections (ssi) after adolescent idiopathic scoliosis (ais) surgery ranges from 0.5% to 7%. there is currently a regain of interest in hybrid constructs, combining lumbar pedicle screws and thoracic sublaminar bands, but some authors have raised concerns about the risk of ssi and the difficulty of bacterial eradication. the goal of this study was therefore to assess the outcomes of ssi after ais surgery using sublaminar bands. | 2016 | 26866646 |