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profile of subgingival microbiota in children with mixed dentition.a diversity of microbial species has been detected in children's oral flora at an early age. to investigate the composition of the subgingival microbiota of different groups of teeth in children with mixed dentition, 40 systemically healthy children, aged 7-8 years, randomly chosen, were examined. subgingival plaque samples were taken from the mesiobuccal sites of 21, 41, 16 and 36 permanent teeth and 53, 73, 64 and 84 deciduous teeth. the samples were cultured for bacterial isolation anaerobica ...200011155173
sensitivity of actinobacillus actinomycetemcomitans and capnocytophaga spp. to the bactericidal action of ll-37: a cathelicidin found in human leukocytes and epithelium.the bactericidal activity of synthetic ll-37, a cathelicidin, was assessed against actinobacillus actinomycetemcomitans (three strains) and capnocytophaga spp. (three strains). all strains were sensitive to ll-37, and exhibited 99% effective dose of 7.5-to-11.6 micrograms/ml. an amidated form of ll-37, pentamide-37, killed with about the same efficacy as ll-37. partial inhibition of killing was noted at physiologic concentrations of nacl, and complete inhibition was observed at 400 mm nacl. at a ...200011154407
[fever and oral mucositis in an immunodepressed patient]. 200011153206
effect of three mouthrinses, containing amine/stannous fluoride, herbal extracts or emser salt on the growth of oral bacteria--an in vitro study.clinical studies have shown the efficacy of mouthrinses in reducing plaque accumulation and inflammation of oral tissues. the aim of this in vitro study was to compare the effect of three mouthrinses: meridol, an organic amine/ stannous fluoride solution; parodontax, containing herbal ingredients; and an 0.8 % emser salt solution, on the growth of oral bacteria and dental plaque.200011147996
checkerboard assessments of serum antibodies to oral microbiota as surrogate markers of clinical periodontal status.this study addresses whether checkerboard assessments of serum igg antibodies to oral bacteria may serve as surrogate markers of clinical periodontal status in epidemiologic studies.200111142661
capnocytophaga canimorsus infection--a fulminant case following a trivial dog-bite injury. 200011081138
microbiological parameters associated with il-1 gene polymorphisms in periodontitis patients.polymorphisms in the cluster of il-1 genes have been significantly associated with the severity of adult periodontitis. the purpose of this study was to compare microbiological parameters in il-1 genotype negative and positive adult subjects with a range of periodontitis severities.200011073323
in vitro susceptibilities of capnocytophaga isolates to beta-lactam antibiotics and beta-lactamase inhibitors.the susceptibilities of 43 pharyngeal isolates of capnocytophaga to beta-lactam antibiotics, alone or in combination with beta-lactamase inhibitors, were tested by an agar dilution method. the 34 beta-lactamase-positive strains were highly resistant to beta-lactams, but the intrinsic activities of clavulanate, tazobactam, and sulbactam against capnocytophaga, even beta-lactamase producers, indicates that these beta-lactamase inhibitors could be used for empirical treatment of neutropenic patient ...200011036049
microbial composition of supra- and subgingival plaque in subjects with adult periodontitis.the purpose of the present study was to compare and relate the microbial composition of supra and subgingival plaque in 23 adult periodontitis subjects (mean age 51 +/- 14 years).200011034118
[evaluation of "helicobacter-selective-medium (nissui seiyaku)" for rapid detection of helicobacter pylori].we evaluated helicobacter selective agar (hsa) medium (nissui pharmaceuticals co., ltd., tokyo, japan), which has been newly developed and has been commercially available since june in 1998. hsa medium strongly inhibited the growth of possible contaminants from gastric biopsy-specimens, such as alpha-streptococci, neisseria species, enterococcus gallinarum, pseudomonas aeruginosa, corynebacterium species, capnocytophaga species, and candida albicans. cultures run in parallel with helicobacter py ...200011004708
[a case report of lung abscess caused by capnocytophaga gingivalis infection].a 48-year-old male was admitted to our hospital because of fever, cough and of loss appetite. chest x-p revealed an abnormal shadow in the left upper lobe. bronchoscopy was performed and capnocytophaga gingivalis was cultured from the bronchial lavage and bronchial curreting fluid. ceftizoxime sodium and clindamycin phosphate was administered intravenously. he was discharged after 30 days. he did not have any immunosuppressive underlying disease including hiv infection and diabetes mellitus whic ...200010965664
image in cardiovascular medicine. myocardial infarction after dog bite. 200010931814
capnocytophaga canimorsus, a potential emerging microorganism in splenectomized patients. 200010929015
protein c substitution in sepsis-associated purpura fulminans.to assess the effect of protein c (pc) substitution on imminent peripheral necroses and overall outcome in patients with sepsis-associated purpura fulminans.200010921567
capnocytophaga keratitis.to review the clinical course, treatment, and visual outcomes of keratitis caused by the gram negative rod capnocytophaga:200010919898
"checkerboard" assessments of periodontal microbiota and serum antibody responses: a case-control study.we explored the association between subgingival microbial profiles and serum igg responses to periodontal microbiota in relation to clinical periodontal status.200010914791
early microbial colonization of permucosal implants in edentulous patients.in edentulous patients, the microbial colonization of permucosal implants of sintered hydroxyapatite was studied. samples were taken from mucosa and dentures before insertion of implants and from supra- and subgingival sites two to 10 weeks after insertion. in total, five patients and 10 implants with clinically healthy peri-implant tissues were studied. the samples were investigated by dark-field microscopy and anaerobic culture. the supragingival plaque of the implants was dominated by gram-po ...198710872401
characterization and cross-reactivity of rabbit antisera to plaque toxins.the effects of heat labile, high molecular weight water-soluble toxins from bacterial plaque on hl60 promyelocytic cells were examined. on gel filtration, four inhibitors of hl60 cell growth and two inhibitors of hela cell growth (pt1, pt2) were detected. the first and third hl60 cell inhibitors corresponded to the two hela cell inhibitors. the last eluted hl60 cell inhibitor (plaque leukotoxin, pl) did not inhibit hela cell growth. anti-pt2 antibodies reduced the activity of enriched pt2 by 20- ...198710870474
microbiology of subgingival plaque from children with localized prepubertal periodontitis.localized prepubertal periodontitis has been described as a host-defect mediated form of bacterially induced periodontitis, with an early onset and rapid progression around a few teeth in children prior to puberty. to further our understanding of the etiology of this disease, we have examined the microbiological components of subgingival dental plaque in 9 children with localized prepubertal periodontitis to determine if patterns of putative pathogens existed, and have compared these results wit ...198710870471
prevalence and microbiology of localized prepubertal periodontitis.loss of crestal alveolar bone at primary teeth was ascertained radiographically in a dental school clinical population of 2264 children. 19 patients (0.84%) demonstrated distinct periodontal bone destruction around one or more primary teeth; in only 2 of these patients had periodontal disease been identified in previous clinical examinations. a microbiological study of 35 subgingival samples from 9 available patients revealed a high prevalence of black-pigmented bacteroides spp., mainly bacteroi ...198710870470
suspected periodontopathic microorganisms and their oral habitats in young children.samples of subgingival plaque from 67 children, 5-7 years of age, were examined for the presence of certain suspected periodontal pathogenic species using the conventional technique of anaerobic sonification, dilution and spiral plating. when this technique was compared with a direct plating procedure which involved no preliminary dispersion and dilution of plaque specimens, it was found that the direct method resulted in double the frequency of children in whom black-pigmented bacteroides (bpb) ...198710870469
waterhouse-friderichsen syndrome secondary to capnocytophaga canimorsus septicemia and demonstration of bacteremia by peripheral blood smear.waterhouse-friderichsen syndrome caused by capnocytophaga canimorsus septicemia was fatal in a previously healthy 47-year-old woman. the patient died suddenly in less than 12 hours after presentation, in spite of supportive measures, including ventilation, antibiotic coverage, pressor therapy, and multiple transfusions of blood products. the diagnosis of infection due to an unusual organism was suspected earlier in the course of management after review of the peripheral blood smear. the importan ...200010835521
microbial pathogens with impaired ability to acquire host iron.successful microbial pathogens must be adept in obtaining growth-essential iron from healthy hosts. some potential pathogens, however, are sufficiently impaired in iron acquisition ability so as to be dangerous mainly in hosts with such iron loading conditions as alcoholism, asplenia, hemochromatosis, beta-thalassemia major, or tobacco smoking. the association of six impaired pathogens (capnocytophaga canimorsis, yersinia enterocolitica and y. pseudotuberculosis, vibrio vulnificus, tropheryma wh ...200010831229
the short-term effect of apically repositioned flap surgery on the composition of the subgingival microbiota.the purpose of this investigation was to examine the short-term effect of apically repositioned flap surgery on clinical and microbiologic parameters in patients with adult periodontitis. a total of 11 patients with moderate to advanced periodontitis received apically repositioned flap surgery. subjects were monitored during a 3-month pretreatment phase, the baseline surgical phase, and for 3 months post-surgery. clinical assessments including plaque accumulation, gingival redness, suppuration, ...199910815594
profile of subgingival microbiota in children with primary dentition.eruption of primary teeth has a great influence on the oral environment by providing suitable niches for bacterial colonization. the aim of the study was to investigate the composition of the subgingival microbiota of primary incisors, canines and molars in 40 systemically healthy children aged 4-5 yr, chosen randomly. subgingival plaque samples were taken from the mesiobuccal sites of primary incisors (61, 81), canines (53, 73) and molars (64, 84). the samples were cultured for bacterial isolat ...200010791707
herpesviruses and periodontopathic bacteria in trisomy 21 periodontitis.little is known about the etiology and pathogenesis of periodontal disease in trisomy 21 patients. this study determined the occurrence of herpesviruses and putative periodontopathic bacteria in trisomy 21 periodontitis.200010776924
streptococcus viridans intra-amniotic infection associated with antecedent cunnilingus.introduction of bacteria into the amniotic cavity has been associated with oral sex through an ascending infectious route. previous reports have implicated both capnocytophaga and fusobacterium nucleatum via this process. we report a case of streptococcus viridans intra-amniotic infection occurring at 25 weeks' gestation. patient questioning revealed a close temporal relationship between the onset of symptoms and previous episodes of cunnilingus. the diagnosis of subclinical bacterial colonizati ...199910755795
isolation of capnocytophaga granulosa from an abscess in an immunocompetent adolescent. 200010722457
periodontopathic bacteria in children with down syndrome.it is widely known that individuals with down syndrome (ds) often develop severe early-onset periodontal diseases. in this study, we examined the prevalence of periodontopathic bacteria in ds children to determine if specific pathogens are acquired in their childhood.200010711615
capnocytophaga ochracea: characterization of a plasmid-encoded extended-spectrum tem-17 beta-lactamase in the phylum flavobacter-bacteroides.a plasmid-encoded extended-spectrum tem beta-lactamase with a pi of 5.5 was detected in a capnocytophaga ochracea clinical isolate. the bla gene was associated with a strong tem-2 promoter and was derived from bla(tem-1a) with a single-amino-acid substitution: glu(104)-->lys, previously assigned to tem-17, which is thus the first tem beta-lactamase to be reported in the phylum flavobacter-bacteroides.200010681352
the effect of scaling and root planing on the clinical and microbiological parameters of periodontal diseases: 12-month results.previously, we reported that srp resulted in a decrease in mean pocket depth and attachment level and reduced prevalence and levels of bacteroidesforsythus, porphyromonas gingivalis, and treponema denticola at 3 and 6 months post-srp in 57 subjects with adult periodontitis. 32 of the 57 subjects were monitored at 9 and 12 months. thus, the purpose of the present investigation was to evaluate the microbial and clinical effects of srp in 32 (mean age 48+/-11) subjects over a 12-month period.200010674959
antithyroid-drug-induced agranulocytosis complicated by life-threatening infections.agranulocytosis is a rare complication of antithyroid drugs, and the aetiologies of community-acquired, life-threatening infections in patients taking these drugs have not previously been systematically described. of 5653 hyperthyroid patients treated with antithyroid drugs at national taiwan university hospital between january 1987 and december 1997, 13 (0.23%) developed agranulocytosis with life-threatening infections. the most common presentations were fever (92%) and sore throat (85%). initi ...199910627862
[meningitis caused by capnocytophaga canimorsus]. 199710622129
pre- and post-implantation microbiota of the tongue, teeth, and newly placed implants.this investigation sought intra-oral sources of species colonizing dental implants.199910599911
longitudinal study of dental implants in a periodontally compromised population.the purpose of this longitudinal study was to determine the clinical status and the composition of the subgingival microbiota of dental implants and natural teeth in patients with a history of periodontitis.199910588495
do not snog the dog: infective endocarditis due to capnocytophaga canimorsus.we present a case of prosthetic valve endocarditis and paravalvular abscess caused by the canine bacteria capnocytophaga canimorsus in a 63-year-old man, who made a habit of snogging his pet dog. capnocytophaga canimorsus can cause culture-negative endocarditis, therefore a high level of clinical awareness and the appropriate isolation techniques are important for making the diagnosis. antibiotic therapy and properly timed excision of the infected focus are recommended.199910554860
microscopy flowcells: perfusion chambers for real-time study of biofilms. 199910547790
establishment of oral anaerobes during the first year of life.anaerobic species constitute a significant part of the bacterial community of the mouth. although the time and species involved in the primary colonization of infants are of great importance by forming the basis for further colonization, the development of the oral anaerobic microflora with age is still inadequately understood. in the present study, time and succession of colonization of oral anaerobes were longitudinally examined in 44 healthy caucasian infants at 2, 6, and 12 months of age. un ...199910520968
capnocytophaga canimorsus peritonitis in a pediatric peritoneal dialysis patient.capnocytophaga canimorsus, a bacterium rarely encountered by clinicians, was responsible for the development of peritonitis in an 18-year-old white male on automated peritoneal dialysis following the puncture of his dialysis tubing by a domestic cat. although more than 100 cases of septicemia caused by c. canimorsus have been reported, this is the first report of the organism causing peritonitis in a patient receiving peritoneal dialysis. of interest, the patient had a prior episode of peritonit ...199910502119
[bites by domestic animals]. 199910495867
second-trimester abortion caused by capnocytophaga sputigena: case report.intra-amniotic infection is often the cause of a second-trimester abortion. the bacterial species involved include bacteria with low pathogenicity like ureaplasma urealyticum and various mycoplasma species. in this case we describe an intra-amniotic infection caused by capnocytophaga sputigena, often found in the normal bacterial flora of the oral cavity, but not in the vagina. oral sex during pregnancy was the most probable source of the infection. the aborted fetus showed signs of pneumonia up ...199910458530
bacteremia due to capnocytophaga species in patients with neutropenia: high frequency of beta-lactamase-producing strains. 199910452663
life-threatening capnocytophaga canimorsus infection after dog bite. 199910396263
beta-lactamase production by oral anaerobic gram-negative species in infants in relation to previous antimicrobial therapy.the frequency of beta-lactamase production in gram-negative bacteria has increased considerably during recent years. in this study, beta-lactamase production by oral anaerobic gram-negative rods isolated from saliva was longitudinally examined for 44 caucasian infants at the ages of 2, 6, and 12 months in relation to their documented exposure to antibiotics. isolates showing decreased susceptibility to penicillin g (1 microg/ml) were examined for beta-lactamase production by using a chromogenic ...199910390208
flow cytometry to monitor phagocytosis and oxidative burst of anaerobic periodontopathogenic bacteria by human polymorphonuclear leukocytes.the reduced susceptibility to phagocytosis found among some periodontopathogenic anaerobes may account for the differences between invasive and non-invasive strains. we applied flow cytometry as a powerful tool to analyze and quantify phagocytosis using standardized cultures of oral anaerobes (porphyromonas gingivalis, prevotella intermedia, p. nigrescens, capnocytophaga gingivalis, c. ochracea, c. sputigena, fusobacterium nucleatum and peptostreptococcus micros) and heparinized whole blood. bac ...199910384401
ub researchers identify oral bacteria likely to trigger heart attack. 199910363505
case records of the massachusetts general hospital. weekly clinicopathological exercises. case 17-1999. a 42-year-old asplenic man with gram-negative sepsis. 199910362827
phospholipid analogue distribution in capnocytophaga.polar lipids of nineteen previously characterised culture collection strains of capnocytophaga were analysed using fast atom bombardment mass spectrometry (fab ms) in negative mode. all strains examined had a major peak at m/z 241, consistent with the expected presence of the pentadecanoate anion. the most intense higher mass anions, consistent with expected presence of phospholipid molecular species, were as follows: m/z 574, 588, 618 and 662 which are consistent with presence of pe(24:2), pe(2 ...199910360312
severe, rapidly progressing peri-implantitis.the replacement of teeth by means of titanium implants is a safe and predictable procedure in most patients. some studies show that a small number of patients lose the majority of their implants. unfortunately, it is impossible to identify these patients prior to surgery. it is important to report such cases so that we may, in the future, be able to identify them before surgery. the present case showed a severe and rapid exfoliation of titanium implants. out of 8 implants inserted in the anterio ...199910355623
hemolytic uremic syndrome due to capnocytophaga canimorsus bacteremia after a dog bite.the hemolytic uremic syndrome (hus) is known to have several causes, including infectious diseases, drugs, pregnancy, and malignant disease. we report a patient who developed acute renal failure attributable to hus in the course of capnocytophaga canimorsus bacteremia. acute tubular necrosis as well as hus should be considered as a cause of acute renal failure in the setting of capnocytophaga canimorsus bacteremia.199910352221
capnocytophaga canimorsus sepsis. 199910328724
comparative microbiological characteristics of failing implants and periodontally diseased teeth.the purpose of this report was to compare the distribution of periodontal pathogens recovered from failing implants and teeth with adult and recurrent forms of periodontitis.199910328655
coenonia anatina gen. nov., sp. nov., a novel bacterium associated with respiratory disease in ducks and geese.taxon 1502 was originally described as a riemerella anatipestifer-like bacterium causing exudative septicaemia in ducks and geese. in the present study, an integrated genotypic and phenotypic approach was used to elucidate the phylogenetic affiliation and taxonomic relationships of 12 strains of taxon 1502. whole-cell protein and fatty acid analyses and an extensive biochemical examination by using conventional tests and several api microtest systems indicated that all isolates formed a homogene ...199910319512
changes of periodontal status in patients with down syndrome during a 7-year period.the development of periodontal disease in down syndrome adolescents (n = 34) was studied clinically and on intraoral radiographs during a 7-yr period. the occurrence of gingival inflammation (gbi), pathological periodontal pockets (>4 mm), sub- and supragingival calculus, alveolar bone height, alveolar bone loss, and the occurrence of the periodontal pathogens actinobacillus actinomycetemcomitans, capnocytophaga, and porphyromonas gingivalis in subgingival plaque were determined. of the subjects ...199910232455
chorioamnionitis with intact membranes caused by capnocytophaga sputigena.we report a case of chorioamnionitis with intact membranes caused by capnocytophaga sputigena. the pregnant woman was hospitalised in preterm labor without fever, neither tenderness, just regular contractions. in spite of the tocolitic treatment the patient gave birth to a girl at 29 weeks' gestation, weighing 1220 g and transferred to intensive care. the newborn had clinical and biological signs of infections and was initially treated by ampicillin, cephalosporin and metronidazol. capnocytophag ...199910221619
growth and hydrolytic enzyme production of capnocytophaga gingivalis on different protein substrates.capnocytophaga gingivalis was grown with proteins (albumin, collagen, mucin and hemoglobin) as carbon and energy sources in chemostat culture. the mu max (0.34 h-1) and biomass yield (0.96 g.l-1) were as high with hemoglobin (3 g.l-1) as with glucose (3 g.l-1) (20). albumin, collagen and mucin also supported an increased mu max, or yield or both, in comparison with basal (tryptone/thiamine) medium. in steady-state, trypsin-like protease specific activity increased 3- to 5-fold in the presence of ...199910219172
fulminant infection by uncommon organisms in animal bite wounds.in 1995 and 1996, 215 patients exposed to different species of animals were treated at the amarnath polyclinic, balasore, in india. among them were two children infected by uncommon organisms, i.e., capnocytophaga canimorsus and pasteurella multocida; the patients recovered with appropriate antibiotic therapy.199810211359
induction of anti-thymocyte/t lymphocyte antibodies in mice injected with lipopolysaccharides from periodontopathic bacteria.we examined the levels of anti-thymocyte/t lymphocyte autoantibody (ata) in the serum of mice injected intraperitoneally with lipopolysaccharides (lps) from periodontopathic bacteria; porphyromonas gingivalis, actinobacillus actinomycetemcomitans, fusobacterium nucleatum, capnocytophaga ochracea, and non-oral escherichia coli. all of the lps induced igm-ata. among these, lps from c. ochracea induced the highest level of igm-ata, whereas that of p. gingivalis induced the lowest. the peritoneal t ...199910207839
microbiota of successful osseointegrated dental implants.the long-term survival of dental implants depends, in part, on control of bacterial infection in the peri-implant region. periodontal pathogens colonized implants symptomatic through infection, whereas the microbiota of successful implants was similar to that of periodontal health. this study examined the impact on the peri-implant microbiota of crown restorations; implant type; length of time of loading; history of implant or periodontal infections; and whether implants replaced single or multi ...199910102550
[capnocytophaga canimorsus infections: a possibly fatal complication of bite wounds].practising veterinarians and their assistants run the risk of being bitten by their patients, mostly cats and dogs, and many have experienced that bites and bite-wound infections can have unpleasant consequences. in recent years, more insight has been gained into a 'new' bacterial infection of bite wounds that not only has severe local effects but also potentially fatal systemic consequences. the bacterium involved is capnocytophaga canimorsus. all bite wounds should be treated adequately, but t ...199910081807
[sepsis due to df2]. 199910065440
relationship of the subgingival microbiota to a chairside test for aspartate aminotransferase in gingival crevicular fluid.the aim of the present study was to evaluate the association between the occurrence of certain specific periodontal pathogens and aspartate aminotransferase (ast) levels in gingival crevicular fluid (gcf).199910052771
[concerning capnocytophaga, taxonomic changes and bibliographic searches]. 199910027187
the effect of chemotherapy on the supragingival plaque of pediatric cancer patients.the anaerobic cultivable flora of the dental plaque was investigated in 16 cancer children at days 0, 7, 14 and 21 of a first cure of chemotherapy. results were compared with those obtained in 16 healthy children. diseased children showed more quantitative variations of the flora than the controls, especially during the first week of chemotherapy. whatever the day of sampling, the flora of the diseased children was significantly less complex than that of the controls. viridans streptococci, capn ...19989930358
microbiological features and crevicular fluid aspartate aminotransferase enzyme activity in early onset periodontitis patients.gingival crevicular fluid (gcf) reflects the immune and inflammatory reactions and the specific host-microbe interactions that lead to periodontal diseases. aspartate aminotransferase enzyme (ast) is one of the components of gcf that is released as a result of cell death. in this study, periodontal sites (4 sites/patient) with a probing depth of > or =5 mm in early onset periodontitis (eop) patients were first examined for the ast levels in gcf by the periogard periodontal tissue monitor. to be ...19999923506
preparation and characterization of an actinomyces naeslundii aggregation factor that mediates coaggregation with porphyromonas gingivalis.intergeneric coaggregation is responsible for the complexity of the microbiota in human dental plaque and is believed to be important in the initial bacterial colonization of the human oral cavity. actinomyces naeslundii, an early colonizer of the tooth surface, may enhance subsequent colonization by porphyromonas gingivalis which is associated with adult periodontitis. the purpose of this study was to isolate and characterize the a. naeslundii aggregation factor (anaf) that mediates coaggregati ...19989879519
detection of dextranase-producing gram-negative oral bacteria.thirty-one strains of 23 gram-negative oral bacterial species were examined for dextran-degrading activity on agar plates containing blue dextran. one strain each of capnocytophaga ochracea, capnocytophaga sputigena, prevotella loescheii, prevotella melaninogenica and prevotella oralis had detectable dextranase activity. the culture supernatants of p. melaninogenica and p. oralis cells contained dextranases of multiple sizes, but those of the other three species had a single size of enzyme. a 56 ...19989872116
analysis of serum antibody responses to periodontopathogens in early-onset periodontitis patients from different geographical locations.serum antibody specificity to oral micro-organisms was used to delineate the pathogens associated with early-onset periodontal diseases in a turkish population. additionally, comparison of the findings to those derived from a clinically similar us patient population described differences in bacterial specific antibody between these 2 geographic regions. serum from 89 (ljp), 86 (rpp) and 94 (normal) subjects was analyzed (elisa) to determine igg antibody to 14 oral micro-organisms. all ljp patien ...19989869349
postsplenectomy capnocytophaga canimorsus sepsis presenting as an acute abdomen.patients with intra-abdominal processes that require prompt surgical intervention, including appendicitis, perforated viscus, ischemic bowel, volvulus, and bowel obstruction, often present with signs and symptoms of an acute abdomen. several medical problems can mimic an acute abdomen. overwhelming postsplenectomy infection is a life-threatening condition that can present with acute abdominal symptoms. the incidence of overwhelming postsplenectomy infection ranges from 1% to 25%, and is caused b ...19989865657
purification of immunosuppressive factor from capnocytophaga ochracea.capnocytophaga, one of the genera of oral bacteria, has been implicated in the pathogenesis of several diseases, including endocarditis, septicaemia and disorders of the oral cavity such as abscesses and periodontal disease. this study examined sonic extracts (se) of capnocytophaga strains for their ability to alter lymphocyte function. the se of tested capnocytophaga caused dose-dependent suppression of spleen cells in response to mitogen. this suppressive effect was heat-labile and sensitive t ...19989856645
images in clinical medicine. capnocytophaga canimorsus sepsis. 19989854119
[evaluation of a new method for susceptibility testing against fastidious and unusual bacteria].the susceptibilities of 154 clinical isolates of fastidious and unusual bacteria were determined by the etest, and were compared with the mics for these strains obtained by the agar dilution method. antimicrobial agents; benzylpenicillin, ampicillin, cefotaxime, imipenem, erythromycin, clindamycin and minocycline were used in this study. in general, the etest mics were rapidly and easily interpreted. the etest mics agreed within +/- 1 log2 and +/- 2 log2 dilution, 87.6% and 98.2% respectively in ...19989847518
infection of a porous polyethylene orbital implant with capnocytophaga.a 68-year-old woman experienced an infection of a porous polyethylene orbital implant caused by capnocytophaga after a dental procedure. the infection was unresponsive to both topical and oral antibiotics and required removal of the porous polyethylene orbital implant. capnocytophaga is a capnophilic, gram-negative bacillus. capnocytophaga is a normal commensal of the mouth and is responsible for both gingivitis and periodontal disease. capnocytophaga is a rare cause of ocular infections. this i ...19989842559
growth differences of capnocytophaga canimorsus strains and some other fastidious organisms on various columbia-based blood agar media.three human isolates of capnocytophaga canimorsus from blood cultures showed no growth when cultivated on sheep blood agar plates based on bbl columbia agar base, whereas the same three strains grew excellently on sheep blood agar plates based on difco columbia agar bases no. 2 or eh. two of the three strains also grew well on blood agar plates based on biomérieux columbia agar. strains that grew better on either difco or biomérieux columbia based blood agar plates were found among eikenella cor ...19959810657
[beware of the dog! a syndrome resembling thrombotic thrombocytopenic purpura associated with capnocytophaga canimorsus septicemia]. 19989775193
subgingival microflora and treatment in prepubertal periodontitis associated with chronic idiopathic neutropenia.prepubertal periodontitis affects both primary and permanent dentition. the purpose of this study was to examine the composition of subgingival microflora of the permanent dentition in an 11-year-old caucasian female, who had premature exfoliation of her deciduous teeth on her 5th year of age, and the response of this condition to the antibiotic therapy and supportive periodontal care. gingival tissues were highly inflamed and alveolar bone loss was detected radiographically. the girl had experi ...19989763332
identification and analyses of periodontal pathogens in taiwan by microbiological tests.the purpose of this study was to use microbiological tests for diagnosis of periodontal diseases in taiwan. anaerobic culture, direct microscopy, indirect immunofluorescence (if), and biochemical tests were used to examine 336 samples for the specific microorganisms in subgingival plaque. the results indicated that gram-negative species and motile bacteria were less frequently detected, and in lower proportion, in samples from healthy sites. the bacteria found frequently in healthy group were th ...19949747334
[multiorgan failure and peripheral gangrene following a superficial dog bite].one case of life-threatening disease caused by the gram-negative rod capnocytophaga canimorsus and a similar case without verification are presented. the severe diseases developed two to three days after a superficial dog bite and were characterized by acute development of septicaemia and fulminant disseminated intravascular coagulation syndrome. moreover, the cases were complicated by renal failure, respiratory insufficiency and peripheral gangrene.19989741264
[bacterial infections as complications of dog bites].dog bites may result in serious bacterial infections with e.g. the gram-negative rods capnocytophaga canimorsus and pasteurella multocida. human disease caused by these microorganisms can be complicated by acute development of septicaemia and/or meningitis followed by disseminated intravascular coagulation syndrome, peripheral gangrene and renal failure. the mortality of c. canimorsus septicaemia is about 23-31%. these severe infections are most often reported in immunocompromised patients and o ...19989741251
preterm birth: associations with genital and possibly oral microflora.opportunistic pathogenic microbes are indigenous to the female lower genital tract and etiologic in many types of pelvic infections and, apparently, a portion of preterm birth (ptb) cases. bacterial vaginosis (bv) is a clinical syndrome based on an altered genital microflora in which gardnerella vaginalis; anaerobic species primarily among prevotella, porphyromonas, bacteroides, peptostreptococcus, and mobiluncus; mycoplasma hominis; and ureaplasma urealyticum become predominant in vaginal secre ...19989722706
capnocytophaga sepsis in a patient with waldenström's macroglobulinemia. 19989709902
[fulminant sepsis by capnocytophaga canimorsus after a dog bite]. 19989706592
the effect of supragingival plaque control on the progression of advanced periodontal disease.the aim of the present trial was to study the effect of meticulous supragingival plaque control on (i) the subgingival microbiota, and (ii) the rate of progression of attachment loss in subjects with advanced periodontal disease. an intra-individual group of sites exposed to non-surgical periodontal therapy served as controls. 12 patients with advanced periodontal disease were subjected to a baseline examination (bl) including assessments of oral hygiene status, gingival condition (bop), probing ...19989696252
fatal septicaemia in a previously healthy man following a dog bite.a rare case of fatal septicaemia after a dog bite in a previously healthy individual is presented and discussed. capnocytophaga canimorsus (df-2 bacterium) was isolated from blood cultures. our case shows the importance of immediate antibiotic treatment for all dog and cat bites, regardless of severity.19989684442
subgingival microflora associated with nifedipine-induced gingival overgrowth.the purpose of this study was to examine the composition of subgingival plaque of 140 periodontal lesions in 35 patients with cardiovascular disorders who were administered nifedipine and manifested nifedipine-induced gingival overgrowth (go). age was inversely associated with the go. plaque index and bleeding index showed a significant association with go, while nifedipine dosage and duration of nifedipine therapy were not found to be significant predictors of go. the gingival inflammation as e ...19989660335
antimicrobial activity of magnolol and honokiol against periodontopathic microorganisms.magnolol (1) and honokiol (2), main compounds from the stem bark of magnolia obovata thunb., were evaluated for an antimicrobial activity against periodontopathic microorganisms, porphyromonas gingivalis, prevotella gingivalis, actinobacillus actinomycetemcomitans, capnocytophaga gingivalis, and veillonella disper, and a cytotoxicity against human gingival fibroblasts and epithelial cells. our results indicate that magnolol and honokiol, although less potent than chlorhexidine, show a significan ...19989619121
beware our "best friend": capnocytophaga canimorsus septicaemia after a dog bite. 19989612464
risk of animal contact in immunocompromised hosts. 19989588438
characterization of a novel n-acetylneuraminic acid-specific fusobacterium nucleatum pk1594 adhesin.fusobacterium nucleatum has been identified as significantly associated with sites with active periodontal disease and, as a group, the oral fusobacteria coaggregate with members of all oral bacteria genera tested. monoclonal antibodies were prepared and used in conjunction with other potential inhibitors, such as simple sugars and amino acids, to characterize coaggregation interactions, of f. nucleatum pk1594. four unique monoclonal antibodies, 5h11, 14c7, 19f2 and 29c12, were obtained by their ...19989573822
identification of bacterial species on or in crevicular epithelial cells from healthy and periodontally diseased patients using dna-dna hybridization.the purpose of this investigation was to identify bacterial species present on or in crevicular epithelial cells in healthy and diseased sites using dna probes. in order to achieve this aim, further improvements were made in the separation of unattached bacteria from those adherent to epithelial cells isolated from the human gingival crevice or periodontal pocket. then the dna probes were used to determine the prevalence of detectable dna from 15 microbial species on or in crevicular epithelial ...19989573819
subgingival microbiota of shallow periodontal pockets in individuals after head and neck irradiation.this study aimed at investigating the subgingival plaque microorganisms of shallow pockets (< or = 5 mm) in subjects who previously received irradiation in the head and neck region for treatment of nasopharyngeal carcinoma. direct microscopy and anaerobic culture were used. subgingival paper point samples were taken from 6 tooth-sites (one/sextant) per subject for direct microscopy (n = 108). another set of paper points was taken from the deepest of the previously selected sites (one per subject ...19989573815
beta-sheet antibiotic peptides as potential dental therapeutics.small, cysteine-rich, beta-sheet peptide antibiotics are found throughout the animalia. though broad spectrum in potential, they may exert selective antimicrobial effects under certain conditions. we have explored the antimicrobial properties of two families of beta-sheet peptide antibiotics, defensins and protegrins, against periodontopathic bacteria. the rabbit defensin np-1 was active against facultative gram-negative bacteria associated with early onset periodontitis, including actinobacillu ...19989573496
supernatant cytotoxicity and proteolytic activity of selected oral bacteria against human gingival fibroblasts in vitro.the purpose of this study was to determine if endodontic bacterial act in vitro on human gingival fibroblast functions via extracellular products. the bacteria used were prevotella nigrescens, capnocytophaga ochracea, peptostreptoccocus micros and actinobacillus actinomycetemcomitans. supernatants were collected from bacterial cultures at the beginning of the stationary phase when their density was similar. toxins that inhibited fibroblast proliferation were found in all culture supernatants of ...19989569986
[retropharyngeal abscess in an adult and an elderly woman].retropharyngeal abscess is reported to be decreasing in frequency in recent years. we report two cases of retropharyngeal abscess that were diagnosed within four years in department of otorhinolaryngology, gifu university hospital. case 1 was a 36-year-old male who was suggested to have an abscess as primary infection and case 2 was a 71-year-old female whose abscess seemed to be a secondary infection following unknown primary infection. endoscopic or open neck drainage as well as antibacterial ...19989545693
dog bites: hidden danger of fulminant sepsis. 19989542707
subgingival distribution of periodontopathic bacteria in adult periodontitis and their susceptibility to minocycline-hcl.the purpose of this study was to investigate the distribution of several periodontopathic bacteria in adult periodontitis, their in vitro susceptibility to minocycline-hcl, and whether the efficacy of the drug changes with a decrease in bacterial susceptibility. twenty-one patients (43 to 75 years old) with 62 periodontal lesions from pockets > or =4 mm participated in the study. after subgingival sampling, an ointment containing 2% minocycline-hcl was applied locally to the selected pockets onc ...19989527568
periodontal status and subgingival microbiota of insulin-dependent juvenile diabetics: a 3-year longitudinal study.this study examined for 3 years the changes in periodontal status and the possible correlations with selected subgingival microbiota and diabetic conditions in a group of 16 insulin-dependent diabetes mellitus (iddm, jd) patients as compared with their 16 healthy cohabiting siblings (hs). jd patients were monitored every 3 months for levels of glycosylated hemoglobin (hba1c). clinical and microbiological parameters were measured 6 weeks before drawing blood to determine levels of hba1c. periodon ...19989526910
capnocytophaga canimorsus in the oral flora of dogs and cats. 19989515691
microbial complexes in subgingival plaque.it has been recognized for some time that bacterial species exist in complexes in subgingival plaque. the purpose of the present investigation was to attempt to define such communities using data from large numbers of plaque samples and different clustering and ordination techniques. subgingival plaque samples were taken from the mesial aspect of each tooth in 185 subjects (mean age 51 +/- 16 years) with (n = 160) or without (n = 25) periodontitis. the presence and levels of 40 subgingival taxa ...19989495612
capnocytophaga bacteremia: clinical features of patients and antimicrobial susceptibility of isolates.capnocytophaga has been recognized as an opportunistic pathogen causing systemic infections in immunocompromised individuals with granulocytopenia and oral ulceration. treatment of capnocytophaga infection is often empiric. we retrospectively analyzed the clinical features of all patients with capnocytophaga bacteremia seen at the national taiwan university hospital between january 1981 and december 1996 and the antimicrobial susceptibility of the isolates recovered from these patients. all the ...19989481064
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