Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
|---|
| necrotizing fasciitis: a life-threatening clinical disorder in uncontrolled type 2 diabetic patients. | we presented 23 patients with necrotizing fasciitis (nf), 15 of whom had uncontrolled diabetes mellitus (dm), for risk factors, clinical signs, laboratory findings and prognosis during the period 1998 and 2006 in istanbul. a hospital incidence of nf was 14.2/100,000 admissions. other risk factors were obesity in 9 and recent surgical trauma in 10 patients. the mean age of the patients with dm was higher than that of the patients with non-dm (58.6+/-12.8 vs 43.0+/-17.2 years, p=0.028). the most f ... | 2008 | 18190995 |
| percutaneous nephrolithotomy of patients with staghorn stone and incidental purulent fluid suggestive of infection. | patients undergoing percutaneous nephrolithotomy (pcnl) sometimes have purulent fluid in the puncture site in spite of having no signs or symptoms of infection preoperatively. we report the safety and effectiveness of pcnl in 45 patients with staghorn renal stones and incidental purulent fluid in the pelvicaliceal system. | 2007 | 18186679 |
| mycotic aneurysm of the infrarenal aorta after drainage of an infected chronic pancreatic pseudocyst: case report and review of the literature. | 2007 | 18186387 | |
| linkage of acquired quinolone resistance (qnrs1) and metallo-beta-lactamase (blavim-1) genes in multiple species of enterobacteriaceae from bolzano, italy. | twenty-four of 209 oxyimino-cephalosporin- and/or aztreonam-resistant enterobacteriaceae collected around bolzano had reduced susceptibility or resistance to carbapenems and gave positive metallo-beta-lactamase (mbl) tests. their resistance mechanisms were investigated. | 2008 | 18184647 |
| xanthogranulomatous pyelonephritis complicated by emphysematous pyelonephritis in a hemodialysis patient. | xanthogranulomatous pyelonephritis and emphysematous pyelonephritis are two uncommon variants of pyelonephritis. the combined occurrence is very rare and has not been described in dialysis patients. we report a 78-year-old woman with end-stage renal disease receiving chronic hemodialysis who presented with a one-week history of vague abdominal pain. during the previous 4 months, she had experienced four episodes of urinary tract infection presenting with fever and pyuria which were improved by a ... | 2007 | 18184527 |
| multiplex pcr amplification assay for the detection of blashv, blatem and blactx-m genes in enterobacteriaceae. | extended-spectrum beta-lactamases (esbls) are often mediated by (bla-)shv, (bla)tem and (bla)ctx-m genes in enterobacteriaceae and other gram-negative bacteria. numerous molecular typing methods, including pcr-based assays, have been developed for their identification. to reduce the number of pcr amplifications needed we have developed a multiplex pcr assay which detects and discriminates between (bla-)shv, (bla)tem and (bla)ctx-m pcr amplicons of 747, 445 and 593 bp, respectively. this multiple ... | 2007 | 18184411 |
| identification of carbapenem-resistant klebsiella pneumoniae harboring kpc enzymes in new jersey. | klebsiella pneumoniae isolates harboring kpc enzymes have been identified in many geographical areas since 2001. numerous problems exist in the detection and treatment of patients with such isolates. the clinical characteristics and molecular epidemiology associated with 12 randomly chosen patients in whom these enzymes were detected by molecular methods are described. this is the first description of the identification of carbapenem-resistant k. pneumoniae isolates harboring kpc beta-lactamases ... | 2007 | 18184049 |
| resistance in gram-negative bacilli in a cardiac intensive care unit in india: risk factors and outcome. | the objective of this study was to compare the risk factors and outcome of patients with preexisting resistant gram-negative bacilli (gnb) with those who develop sensitive gnb in the cardiac intensive care unit (icu). of the 3161 patients ( n=3,161) admitted to the icu during the study period, 130 (4.11%) developed health care-associated infections (hais) with gnb and were included in the cohort study. pseudomonas aeruginosa (37.8%) was the most common organism isolated followed by klebsiella sp ... | 2008 | 18182755 |
| identification of klebsiella pneumoniae carbapenemase in sweden. | 2007 | 18179763 | |
| shv-type extended-spectrum beta-lactamase (esbl) are encoded in related plasmids from enterobacteria clinical isolates from mexico. | in this work we report the molecular characterization of beta-lactam antibiotics resistance conferred by genes contained in plasmids from enterobacteria producing extended-spectrum beta-lactamases (esbl). | 2007 | 18176701 |
| [pancytopenia induced by two low-dose injections of methotrexate in a patient treated for ulcerative colitis]. | a 72 year-old man with steroid-dependent ulcerative colitis was treated with methotrexate at 25 mg subcutaneous weekly. three days after the second injection of methotrexate a pancytopenia occurred associated with a klebsiella pneumoniae septicemia which evolution was favourable under treatment. pancytopenia is a rare but severe adverse effect of low-dose methotrexate therapy. in our patient the risk factors were age upper than 65 years, renal insufficiency and hypoalbuminemia. this report empha ... | 2007 | 18176366 |
| identification of the 4-hydroxycinnamate decarboxylase (pad) gene of klebsiella oxytoca. | a 7.1-kbp dna fragment isolated from a wild strain of klebsiella oxytoca was sequenced, leading to the identification of 10 open-reading frames (orfs), including a 504-bp pad gene. the pad gene of the gram-negative bacterium was subsequently expressed in escherichia coli as a chimeric pad. the deduced amino acid (aa) sequence of the pad gene from wild-type k. oxytoca showed approximately 50% homology to those of other bacterial pads from gram-positive bacilli plus a coccus. these data and a geno ... | 2008 | 18175898 |
| effectiveness of glycerol mono-oleate as a biosealant. | the number of femoral artery catheterizations will increase over the next decade to more than 9 million worldwide. accordingly, a new era of access site management with vascular closure techniques utilizing biologics are being developed and implemented. glycerol mono-oleate (gmo) is one such biologic - a biodegradable compound that changes from a solid phase to a bioadhesive swollen semisolid phase when exposed to aqueous solutions and heat. we assessed whether gmo would: 1) achieve hemostasis m ... | 2008 | 18174616 |
| type 3 fimbriae, encoded by the conjugative plasmid pola52, enhance biofilm formation and transfer frequencies in enterobacteriaceae strains. | the conjugative plasmid pola52, which confers resistance to olaquindox and other antimicrobial agents through a multidrug efflux pump, was investigated for its ability to promote biofilm formation in escherichia coli. screening of a transposon-mutagenized pola52 clone library revealed several biofilm-deficient mutants, which all mapped within a putative operon with high homology to the mrkabcdf operon of klebsiella pneumoniae, where these genes are responsible for type 3 fimbriae expression, att ... | 2008 | 18174137 |
| oral carriage of yeasts and coliforms in stroke sufferers: a prospective longitudinal study. | to investigate prospectively the qualitative and quantitative changes in oral carriage of yeasts and coliforms in southern chinese people suffering from stroke. | 2008 | 18173450 |
| [prevalence of extended-spectrum beta-lactamases in nosocomial escherichia coli and klebsiella spp. strains isolated from blood cultures]. | the aim of this study was to determine the prevalence of extended-spectrum beta-lactamases (esbls) in nosocomial bacteremia isolates of escherichia coli, klebsiella pneumoniae and klebsiella oxytoca at hacettepe university adult hospital in ankara, turkey. a total of 344 blood culture isolates of e. coli (n=244), k. pneumoniae (n=86) and k. oxytoca (n=34) were included in the study from january 2003 to november 2005. only one isolate from one patient was tested in the study. the isolates with ce ... | 2007 | 18173077 |
| descending necrotizing mediastinitis: unique complication of central venous catheterization. | central venous catheter placement is a common procedure in the intensive care unit. however, these devices are not without complications. we describe the first reported case of descending necrotizing mediastinitis secondary to central venous catheterization without evidence of associated vascular perforation. | 2007 | 18171121 |
| [surveillance of antimicrobial resistance among nosocomial gram-negative pathogens from 15 teaching hospitals in china in 2005]. | to investigate the antimicrobial resistance among the nosocomial gram-negative pathogens from 15 teaching hospitals located in different areas in china in 2005. | 2007 | 18167265 |
| community-acquired klebsiella oxytoca causing splenic abscess. | 2008 | 18164642 | |
| epidemiology and clinical outcomes of community-acquired pneumonia in adult patients in asian countries: a prospective study by the asian network for surveillance of resistant pathogens. | appropriate antimicrobial treatment of community-acquired pneumonia (cap) should be based on the distribution of aetiological pathogens, antimicrobial resistance of major pathogens, clinical characteristics and outcomes. we performed a prospective observational study of 955 cases of adult cap in 14 hospitals in eight asian countries. microbiological evaluation to determine etiological pathogens as well as clinical evaluation was performed. bronchopulmonary disease (29.9%) was the most frequent u ... | 2008 | 18162378 |
| effects of ethanol on cytokine production after surgery in a murine model of gram-negative pneumonia. | both alcohol abuse and surgery have been shown to impair immune function. the frequency of postoperative infectious complications is 2- to 5-fold increased in long-term alcoholic patients, leading to prolonged hospital stay. following surgery, an increase in interleukin (il)-6 has been shown to be associated with increased tissue injury and interleukin 1-(il-10) is known to represent an anti-inflammatory signal. the purpose of this study was to test the hypothesis that several days of excess alc ... | 2008 | 18162079 |
| [coproduction of qnrb and arma from extended-spectrum beta-lactamase-producing klebsiella pneumoniae]. | multidrug-resistant enterobacteriaceae is a worldwide problem. although various resistance mechanisms have been recognized with increasing frequency, only a few cases of triple resistance of extended-spectrum beta-lactamase (esbl)-producing klebsiella pneumoniae have been reported. this study was designed to evaluate the coexistence of qnr (qnra, qnrb, and qnrs) and 16s rrna methylase (arma, rmta, rmtb, and rmtc) in esbl-producing k. pneumoniae. | 2007 | 18160833 |
| detection of esbls using third & fourth generation cephalosporins in double disc synergy test. | 2007 | 18160757 | |
| the incidence of infectious diseases after renal transplantation: a single-centre experience. | this single-centre study was designed to investigate the incidence of infections and their causative pathogens during the first three months after renal transplantation (rtx) in patients who had undergone the procedure in 2005 (n=174). we compared this group of patients with a previous one (1998-2000, n=437). in 2005, infection was diagnosed in 82 patients (47%). symptomatic lower urinary tract infection (uti) was present in 43 patients (25%), pyelonephritis in 15 (8.6%), and urosepsis in 7 (4%) ... | 2008 | 18160263 |
| susceptibility of community gram-negative urinary tract isolates to mecillinam and other oral agents. | to determine the susceptibility of community outpatient gram-negative urinary tract isolates to mecillinam and other commonly used oral agents. | 2001 | 18159352 |
| occurrence of proteus mirabilis associated with two species of venezuelan oysters. | the fecal contamination of raw seafood by indicators and opportunistic pathogenic microorganisms represents a public health concern. the objective of this study was to investigate the presence of enteric bacteria colonizing oysters collected from a venezuelan touristic area. oyster samples were collected at the northwestern coast of venezuela and local salinity, ph, temperature, and dissolved oxygen of seawater were recorded. total and fecal coliforms were measured for the assessment of the micr ... | 2007 | 18157401 |
| [emergence of ctx-m-12 and a novel ctx-m type extended-spectrum beta-lactamaseproducing klebsiella pneumoniae.]. | the aims of this study were to survey the nation-wide susceptibilities of klebsiella pneumoniae isolates against ceftazidime and cefotaxime and to determine the prevalence of class a extended-spectrum beta-lactamases (esbls). | 2006 | 18156694 |
| contribution of fucose-containing capsules in klebsiella pneumoniae to bacterial virulence in mice. | bacterium klebsiella pneumoniae (kp) contains a prominent capsule. clinical infections usually are associated with pneumonia or urinary tract infection (uti). emerging evidence implicates kp in severe liver abscess especially in diabetic patients. the goal of this study was to investigate the capsular polysaccharides from kp of liver abscess (hepatic-kp) and of uti-kp. the composition of capsular polysaccharides was analyzed by capillary high-performance liquid chromatography (hplc, dionex syste ... | 2008 | 18156307 |
| orthodox and unorthodox clavulanate combinations against extended-spectrum beta-lactamase producers. | clavulanate is a highly effective inhibitor of extended-spectrum beta-lactamases (esbls) in detection tests, but the commercial amoxycillin-clavulanate and ticarcillin-clavulanate combinations have borderline activity, at best, against most esbl producers. oxyimino-cephalosporin-clavulanate combinations are active in vitro against most esbl-producing escherichia coli and klebsiella spp. isolates at < or =1-2 mg/l but are compromised against enterobacter spp., whether esbl-producing or not, where ... | 2008 | 18154546 |
| antibiotic policy and prescribing strategies for therapy of extended-spectrum beta-lactamase-producing enterobacteriaceae: the role of piperacillin-tazobactam. | therapy of infections caused by extended-spectrum beta-lactamase (esbl)-producing bacteria with an antimicrobial to which they are resistant results in treatment failure, higher cost and increased mortality. the clsi recommends reporting esbl-producing strains of escherichia coli, klebsiella spp. and proteus spp. as resistant to all penicillin, true cephalosporin and monobactam antimicrobials, but as susceptible to beta-lactam-beta-lactamase inhibitor combinations, including piperacillin-tazobac ... | 2008 | 18154544 |
| prevalence and clonality of extended-spectrum beta-lactamases in asia. | asia is almost certainly a part of the world in which extended-spectrum beta-lactamases (esbls) have emerged de novo, with some early antimicrobial resistance studies showing high levels of the esbl phenotype, particularly among klebsiella, and most notably in china, korea, japan and india. there is a lack of genotyping studies but work from the late 1990s suggests that shv-5 and shv-12 were most common then, with only very rare reports of tem-related esbl genes. as in other parts of the world, ... | 2008 | 18154540 |
| prevalence and spread of extended-spectrum beta-lactamase-producing enterobacteriaceae in europe. | extended-spectrum beta-lactamases (esbls) represent a major threat among resistant bacterial isolates. the first types described were derivatives of the tem-1, tem-2 and shv-1 enzymes during the 1980s in europe, mainly in klebsiella pneumoniae associated with nosocomial outbreaks. nowadays, they are mostly found among escherichia coli isolates in community-acquired infections, with an increasing occurrence of ctx-m enzymes. the prevalence of esbls in europe is higher than in the usa but lower th ... | 2008 | 18154538 |
| extended-spectrum beta-lactamases in north america, 1987-2006. | extended-spectrum beta-lactamases (esbls) derived from the tem-1 beta-lactamase were first identified in the usa in outbreak strains of klebsiella pneumoniae in the middle to late 1980s, together with the shv-5 esbl. the tem-10, tem-12 and tem-26 enzymes have remained in us hospitals, but have been joined by other esbls that are variants of the shv-1 broad-spectrum beta-lactamase. in the most recent surveys from hospitals in the eastern part of the usa, the most prominent esbls have been the shv ... | 2008 | 18154537 |
| extended-spectrum beta-lactamases and the permeability barrier. | the outer membrane of gram-negative bacteria represents a barrier for penetration of hydrophilic compounds. loss of porins (water-filled protein channels) contributes to antimicrobial resistance, particularly when additional mechanisms of resistance are expressed. many studies on the structure and regulation of porins in escherichia coli k-12 are available, but there is little information concerning clinical isolates of this species. in klebsiella pneumoniae, two major porins, ompk35 and ompk36, ... | 2008 | 18154531 |
| quantitative studies on the origin and characteristics of streptomycin-fast variants of klebsiella pneumoniae. | 1949 | 18139404 | |
| klebsiella pneumoniae associated with infantile diarrhea. | 1949 | 18131770 | |
| experimental klebsiella meningitis treated with intrathecal and intramuscular streptomycin. | 1949 | 18120065 | |
| [not available]. | 1948 | 18119512 | |
| the effect of ultrasonic waves upon klebsiella pneumoniae, saccharomyces cerevisiae, miyagawanella felis, and influenza virus a. | 1949 | 18116902 | |
| the diagnosis of klebsiella pneumoniae (friedländer's bacillus) from the gastrointestinal tract of normal healthy adults. | 1949 | 18113423 | |
| [not available]. | 1948 | 18099467 | |
| overexpression, purification and crystallization of the tetrameric form of sorc sorbitol operon regulator. | the sorbitol operon regulator (sorc) regulates the metabolism of l-sorbose in klebsiella pneumonia. sorc was overexpressed in escherichia coli and purified, and crystals were obtained of a tetrameric form. a single crystal showed x-ray diffraction to 3.20 a. the crystal belongs to space group p2(1)2(1)2(1), with unit-cell parameters a = 91.6, b = 113.3, c = 184.1 a. analysis of the molecular-replacement solution indicates the presence of four sorc molecules in the asymmetric unit. | 2008 | 18097095 |
| ability of organic and inorganic bedding materials to promote growth of environmental bacteria. | the major objective of this study was to contrast the ability of 4 commonly utilized bedding materials to promote growth of environmental bacteria under controlled conditions. a second objective was to describe the relationship between bacterial growth and specific biochemical or nutritional properties of these bedding materials. unused samples of clean sand (cs; n = 20), recycled sand (rs; n = 21), digested manure solids (ds; n = 15), and shavings (sh; n = 15) were collected from bedding storag ... | 2008 | 18096936 |
| [prevalence of extended-spectrum beta-lactamases in escherichia coli and klebsiella pneumoniae from daejeon]. | extended-spectrum beta-lactamases (esbls) are cephalosporinases that confer resistance to a wide variety of oxyimino cephalosporins and create serious therapeutic problems. although esbls have been reported with increasing frequency in korea, their prevalence and genotypic distribution in daejeon remain unknown. this study was designed to evaluate the occurrence and genotypic distributions of esbl-producing escherichia coli and klebsiella pneumoniae in daejeon. | 2007 | 18094599 |
| [microorganisms isolated from blood cultures and their antimicrobial susceptibility patterns at a university hospital during 1994-2003]. | blood culture is important for the determination of the etiologic agent of bacteremia. analysis of blood culture results and antimicrobial susceptibility trend can provide clinicians with relevant information for the empirical treatment of patients. | 2007 | 18094587 |
| interleukin-17 as an effector molecule of innate and acquired immunity against infections. | interleukin (il)-17 is a proinflammatory cytokine which induces differentiation and migration of neutrophils through induction of cytokines and chemokines including granulocyte-colony stimulating factor and cxcl8/il-8. il-17-producing cd4(+) t cells (th17) have pivotal role in pathogenesis of autoimmune diseases. il-17 is also involved in protective immunity against various infections. il-17 has important role in induction of neutrophil-mediated protective immune response against extracellular b ... | 2007 | 18094532 |
| distribution of conjugative-plasmid-mediated 16s rrna methylase genes among amikacin-resistant enterobacteriaceae isolates collected in 1995 to 1998 and 2001 to 2006 at a university hospital in south korea and identification of conjugative plasmids mediating dissemination of 16s rrna methylase. | the distribution of conjugative-plasmid-mediated 16s rrna methylase genes among amikacin-resistant enterobacteriaceae collected between 1995 and 1998 and between 2001 and 2006 at a university hospital in south korea was examined, and conjugative plasmids carrying the 16s rrna methylase genes were characterized by pcr-based replicon typing and by determination of their antimicrobial resistance pattern. among the 7,127 isolates, 463 isolates showed a high level of resistance to amikacin, and 218 o ... | 2008 | 18094126 |
| microorganisms present in discharging otitis media in a group of patients in kathmandu. | discharge from the ear is one of the commonest symptoms of infections of the ear. to study the major strains of bacteria encountered in ear discharges, this study was conducted from july 1999, to june 2001 in the microbiology laboratory of om hospital. a total of 115 patients, of 6-35 years of age clinically diagnosed as discharging otitis media were studied. in 60.9% single organism and in 26.08% two organisms were isolated. results revealed that, staphylococcus aureus (34.3%), klebsiella pneum ... | 2007 | 18092440 |
| antibiotic susceptibility pattern of urinary isolates in imphal (manipur), india. | the present study was conducted to detect aerobic causative agents of urinary tract infection (uti) and their antibiogram pattern. this study was carried out in the department of microbiology, regional institute of medical sciences (rims), imphal, manipur, india. a total of 1,109 clean catched midstream urine samples were collected, out of which 459 (40.4%) samples grew potential pathogens causing uti. escherichia coli were the predominant 334 (72.8%) bacterial pathogen followed by klebsiella sp ... | 2007 | 18092433 |
| urinary tract infections following renal transplantation: a single-center experience. | although infectious complications are the second most common cause of death after transplantation, there appears to be insufficient data regarding the impact of urinary tract infections (utis) on graft outcome and patient mortality and morbidity. in this study, we evaluated the incidence, risk factors, and long-term effects of utis on graft function. | 2007 | 18089338 |
| fournier's gangrene: ten-year experience in a medical center in northern taiwan. | fournier's gangrene is a life-threatening infection. the mortality is still high despite the rapid advancement of modern intensive care and surgical technique. in this study, we present our institution's recent experience with a large series of patients with fournier's gangrene. | 2007 | 18087630 |
| in vitro activity of isepamicin and other aminoglycosides against clinical isolates of gram-negative bacteria causing nosocomial bloodstream infections. | isepamicin is a newly introduced aminoglycoside in taiwan. since in vitro data for isepamicin against nosocomial gram-negative bloodstream infection from taiwan are limited, we compared the activity of isepamicin, amikacin, gentamicin and tobramycin against nosocomial gram-negative blood isolates. | 2007 | 18087627 |
| extended-spectrum beta-lactamases in ceftazidime-resistant escherichia coli and klebsiella pneumoniae isolates in turkish hospitals. | to study the prevalence of tem-, shv- and ges-type beta -lactamases among escherichia coli and klebsiella pneumoniae strains having ceftazidime mics higher than 2 mg/l. | 2007 | 18087082 |
| carbapenem-resistant isolates of klebsiella pneumoniae in china and detection of a conjugative plasmid (blakpc-2 plus qnrb4) and a blaimp-4 gene. | 2008 | 18086850 | |
| isolation and purification of enterocin e-760 with broad antimicrobial activity against gram-positive and gram-negative bacteria. | strain nrrl b-30745, isolated from chicken ceca and identified as enterococcus durans, enterococcus faecium, or enterococcus hirae, was initially identified as antagonistic to campylobacter jejuni. the isolate produced a 5,362-da bacteriocin (enterocin) that inhibits the growth of salmonella enterica serovar enteritidis, s. enterica serovar choleraesuis, s. enterica serovar typhimurium, s. enterica serovar gallinarum, escherichia coli o157:h7, yersinia enterocolitica, citrobacter freundii, klebs ... | 2008 | 18086839 |
| predictors of carbapenem-resistant klebsiella pneumoniae acquisition among hospitalized adults and effect of acquisition on mortality. | carbapenem-resistant klebsiella pneumoniae (crkp) is an emerging nosocomial pathogen. little is known about its risk factors or mortality. we performed a case-case-control study to assess the risks for crkp isolation and a retrospective cohort study to assess mortality in three groups of hospitalized adults: (i) patients from whom crkp was isolated, (ii) patients from whom carbapenem-susceptible klebsiella spp. (csks) were isolated, and (iii) controls from whom no klebsiella spp. were isolated. ... | 2008 | 18086836 |
| a multiplex pcr-based reverse line blot hybridization (mpcr/rlb) assay for detection of bacterial respiratory pathogens in children with pneumonia. | to develop and evaluate a novel method for simultaneous identification of 12 potential bacterial pathogens in children with community-acquired pneumonia. | 2008 | 18085683 |
| application of klebsiella oxytoca immobilized cells on the treatment of cyanide wastewater. | klebsiella oxytoca, isolated from cyanide-containing industrial wastewater, has been shown to be able to biodegrade cyanide to non-toxic end products. the technology of immobilized cells can be applied in biological treatment to enhance the efficiency and effectiveness of biodegradation. in this study, potassium cyanide was used as the target compound and both alginate and cellulose triacetate techniques were applied for the preparation of immobilized cells. results from this study show that kcn ... | 2008 | 18082868 |
| klebsiella pneumoniae endophthalmitis with associated hepatic abscess. | klebsiella pneumoniae liver abscess is known to be associated with metastatic endophthalmitis, with most cases clustered in taiwan. we report a case of klebsiella liver abscess with metastatic endophthalmitis in a nondiabetic haitian man without underlying medical problems. | 2007 | 18081178 |
| [characterization of qnr gene for plasmid-mediated quionlone resistance]. | to explore the distribution of qnr gene and broad spectrum p-lactamase (esbls) gene in gram-negative bacteria which were isolated from our hospital patients. | 2007 | 18080568 |
| [estimation of the contribution of the small plasmids in creation of esbl phenotype among clinical and ambulatory isolates of the enterobacteriaceae]. | here we demonstrated that the small plasmids below (20 kpb) are responsible for maintaining and dissemination of esbl phenotype among the different species of enterobacteriaceae family. the similarity of plazmid profiles isolated from e. coli and klebsiella pneumoniae and k. oxytoca suggests possibility of the exchange of these plazmids between two mentioned species of bacteria. | 2007 | 18078117 |
| [colopleural fistula caused by recurrence of gastric cancer; report of a case]. | perforation of colon into the pleural space without diaphragmatic hernia is extremely rare. this report illustrates a case of pneumo-pyothorax caused by perforation of metastatic tumor of the transverse colon of a 67-year-old woman with a history of total gastrectomy and splenectomy for advanced gastric carcinoma 4 years before. the patient was admitted to our hospital presenting with fever and dyspnea, which subsided after a thoracic drainage. cultures of drained effusion revealed escherichia c ... | 2007 | 18078093 |
| comparative in vitro activity of tigecycline against aerobic and facultative isolates recovered from hospitalized patients: an argentinean multicenter study. | tigecycline, the 9-t-butylglycylamino derivative of minocycline is the first commercially available glycylcycline exhibiting an extended spectrum of antibacterial activity due to its capacity to evade the tetracycline ribosomal and efflux resistance mechanisms. we conducted a collaborative in vitro study determining the activity of tigecycline compared to 14 antimicrobials against clinically relevant isolates obtained from adult patients hospitalized in 9 argentinean institutions. minimum inhibi ... | 2007 | 18077902 |
| biological screening of some turkish medicinal plant extracts for antimicrobial and toxicity activities. | screening of antibacterial activity and toxicity of 22 aqueous plant extracts from 17 turkish plants was conducted. antibacterial activity was performed with six bacteria including escherichia coli, pseudomonas aeruginosa, klebsiella pneumoniae, streptococcus pyogenes, staphylococcus aureus and staphylococcus epidermidis. extracts of tussilago farfara leaves, helichyrsum plicatum flowers, solanum dulcamara aerial parts and urtica dioica leaves gave the best inhibitory activity against s. pyogene ... | 2008 | 18075897 |
| klebsiella pneumoniae flocculation dynamics. | the bacterial pathogen klebsiella pneumoniae is a cause of community- and hospital-acquired lung, urinary tract and blood stream infections. it is a common contaminant of indwelling catheters and it is theorized in that context that systemic infection follows shedding of aggregates off of surface-adherent biofilm colonies. in an effort to better understand bacterial proliferation in the host bloodstream, we develop a pde model for the flocculation dynamics of klebsiella pneumoniae in suspension. ... | 2008 | 18071828 |
| clinical and economic impact of common multidrug-resistant gram-negative bacilli. | 2008 | 18070961 | |
| in vitro activities of doripenem and six comparator drugs against 423 aerobic and anaerobic bacterial isolates from infected diabetic foot wounds. | against 182 anaerobe and 241 aerobe strains obtained from diabetic foot infections, doripenem was the most active carbapenem against pseudomonas aeruginosa (mic(90), 2 microg/ml), more active than imipenem against proteus mirabilis, and ertapenem was more active against escherichia coli and klebsiella spp. the mic(50) and mic(90) values were < or =0.125 microg/ml for methicillin-sensitive staphylococcus aureus and all streptococci and 0.25/1 for bacteroides fragilis. | 2008 | 18070958 |
| [klebsiella pneumoniae septicaemia and meningitis in a diabetic patient with an hepatic abscess]. | klebsiella pneumoniae infections show particular features depending on the geographical localization as well as comorbidity factors. we are presenting the case of a european patient with diabetes mellitus who presented a septicaemia, a meningitis as well as an hepatic abscess due to a k. pneumoniae and whose evolution was excellent under antibiotics. usually described among asian patients, the primary hepatic k. pneumoniae abscess, which is a clinical entity recently described, can give rise to ... | 2007 | 18069521 |
| [attention-getting cross infections: extended-spectrum beta-lactamase-producing bacterial infections]. | 2007 | 18069300 | |
| the antimicrobial activity of copper and copper alloys against nosocomial pathogens and mycobacterium tuberculosis isolated from healthcare facilities in the western cape: an in-vitro study. | clinical isolates of meticillin-resistant staphylococcus aureus (mrsa), klebsiella pneumoniae, pseudomonas aeruginosa, acinetobacter baumannii, candida albicans and mycobacterium tuberculosis (mtb) were tested against copper (cu) and its alloys. stainless steel and polyvinylchloride (pvc) were used as controls. the amount of cu required to inhibit test isolates at room temperature (24 degrees c) and at 4 degrees c was determined. at room temperature, cu, dzr brass (cu 62%, pb 2.5%, arsenate 0.13 ... | 2008 | 18069086 |
| activities of the frog skin peptide, ascaphin-8 and its lysine-substituted analogs against clinical isolates of extended-spectrum beta-lactamase (esbl) producing bacteria. | extended-spectrum beta-lactamase (esbl)-producing gram-negative bacteria are becoming increasingly prevalent and their antibiotic resistance necessitates novel therapeutic intervention. ascaphin-8 is a cationic alpha-helical peptide that shows broad-spectrum antibacterial activity but is also toxic to human erythrocytes (lc(50)= 55 microm). this study assesses the activity of ascaphin-8, and a series of l-lysine-substituted analogs, against a range of clinical isolates of esbl-producing bacteria ... | 2008 | 18068868 |
| upper and lower urinary tract infection caused by klebsiella pneumoniae serotype k2 and ctx-m-15 beta-lactamase-producing serotype k1: a case report and characterization of serum killing resistance. | ctx-m-15 beta-lactamase-producing klebsiella pneumoniae serotype k1 was isolated from a patient with fatal upper urinary tract infection (uti) complicated by sepsis caused by k. pneumoniae serotype k2. transfer of a ctx-m-15 beta-lactamase plasmid from the k1 to the k2 strain was observed. however, plasmid acquisition by the k2 strain did not occur in vivo, suggesting that the k1 strain might not have contributed directly to the upper uti. in addition, effects of k serotypes and plasmid acquisit ... | 2008 | 18065678 |
| bloodstream infections caused by multidrug-resistant klebsiella pneumoniae producing the carbapenem-hydrolysing vim-1 metallo-beta-lactamase: first italian outbreak. | to investigate the first italian outbreak of bloodstream infections caused by multidrug-resistant (mdr) klebsiella pneumoniae producing metallo-beta-lactamase (mbl), which occurred in three wards of one large tertiary-care hospital in genoa, italy, from september 2004 to march 2005. | 2008 | 18065411 |
| [epidemiology and susceptibility profile of blood culture isolates in an intensive care unit (2002-2005)]. | the aim of our study was to determine the epidemiological profile and the antibiotics susceptibility of bacteria identified in blood culture in the intensive care unit, to improve empirical antibiotherapy. | 2008 | 18065180 |
| [mutations in gyra and gyrb genes among strains of gram-negative bacilli isolated from chilean hospitals and their relation with resistance to fluoroquinolones]. | a progressive frequency of resistance to fluoroquinolones is observed among gram-negative bacilli. | 2007 | 18064363 |
| evaluation of risk factors for the acquisition of bloodstream infections with extended-spectrum beta-lactamase-producing escherichia coli and klebsiella species in the intensive care unit; antibiotic management and clinical outcome. | controlled studies that address risk factors for, and clinical outcomes after, infection with extended-spectrum beta-lactamase (esbl)-producing organisms are scant, particularly in the intensive care unit (icu). our objectives were to elucidate risk factors for the acquisition of esbl-producing organisms in icu; and to compare mortality in patients with esbl- and non-esbl bloodstream infections (bsis) after controlling for disease severity and timeliness of appropriate antibiotic therapy. a retr ... | 2008 | 18063198 |
| biological activity of phenylpropionic acid isolated from a terrestrial streptomycetes. | the strain anu 6277 was isolated from laterite soil and identified as streptomyces sp. closely related to streptomyces albidoflavus cluster by 16s rrna analysis. the cultural, morphological and physiological characters of the strain were recorded. the strain exhibited resistance to chloramphenicol, penicillin and streptomycin. it had the ability to produce enzymes such as amylase and chitinase. a bioactive compound was isolated from the strain at stationary phase of culture and identified as 3-p ... | 2007 | 18062653 |
| multiplex-pcr assay for identification of klebsiella pneumoniae isolates carrying the cps loci for k1 and k2 capsule biosynthesis. | multiplex-pcr assay for identification of klebsiella pneumoniae isolates carrying gene clusters for biosynthesis of capsular polysaccharide (cps) types k1 and k2 was developed. genes wzc and orf10 of the cps cluster were applied as k1 and k2 specific markers respectively. the assay specificity was confirmed using 147 isolates of klebsiella spp. including 77 k-antigen reference strains. the multiplex-pcr assay was found simple and cost-effective tool for identification of k. pneumoniae clinical i ... | 2007 | 18062647 |
| existence of sinorhizobium meliloti genomic fragment hybridizing with the nifm gene of klebsiella pneumoniae. | a novel finding that genomic restriction fragments of symbiotic nitrogen fixer s. meliloti hybridized with nifm gene probe of the free-living diazotroph klebsiella pneumoniae is reported. when smai endonuclease was used to digest s. meliloti dna, a unique hybridizing band was obtained. | 2007 | 18062196 |
| biodegradation of chlorpyrifos by klebsiella sp. isolated from an activated sludge sample of waste water treatment plant in damascus. | a chlorpyrifos (cpy)-degrading bacterial strain was isolated from an activated sludge sample collected from the damascus wastewater treatment plant, syria. the isolation of klebsiella sp. was facilitated by the addition of cpy at a rate of 3.84 g/l of sludge weekly (selection pressure). identification of klebsiella sp. was done using major staining and biochemical differentiation tests (gram stain, cytochrome oxidase and some relevant saccharide fermentation tests using biochemical assays). kleb ... | 2007 | 18062192 |
| aerosolized colistin as adjunctive treatment of ventilator-associated pneumonia due to multidrug-resistant gram-negative bacteria: a prospective study. | ventilator-associated pneumonia (vap) remains the leading cause of death in patients with intensive care unit (icu) acquired infections associated with an attributable mortality around 30%. increasing antimicrobial resistance in patients with vap challenges intensivists to search for alternative therapeutic options. there is scarcity of data in the literature concerning the administration of aerosolized colistin in critically ill patients with vap due to multidrug-resistant (mdr) gram-negative p ... | 2008 | 18060758 |
| diverse endophytic nitrogen-fixing bacteria isolated from wild rice oryza rufipogon and description of phytobacter diazotrophicus gen. nov. sp. nov. | twenty-three nitrogen-fixing bacteria were isolated from surface-sterilized stems and roots of wild rice oryza rufipogon. four clusters were defined among these bacteria by sds-page protein patterns and further confirmed by is-pcr finger-printing analysis. phylogenetic analysis of 16s rrna gene sequences showed that the representative strains ls 8 and ls 18 of cluster ii formed a monophyletic group sharing 94.0-97.3% similarities with defined enterobacterial species within the genera salmonella, ... | 2008 | 18060384 |
| antibiotic resistance in children with complicated urinary tract infection. | to determine the resistance of antibiotics for complicated urinary tract infection (uti), including urinary tract anomaly (uta), for empirical antibiotic therapy of complicated uti. | 2007 | 18060215 |
| prevalence and antimicrobial susceptibility pattern of extended-spectrum beta-lactamase-producing enterobacteriaceae in the united arab emirates. | to investigate the prevalence and antibiotic susceptibility pattern of extended-spectrum beta-lactamases (esbl)-producing enterobacteriaceae among patients in the united arab emirates. | 2008 | 18059098 |
| biliary tract infection and bacteraemia: presentation, structural abnormalities, causative organisms and clinical outcomes. | biliary tract infection is a common cause of bacteraemia and is associated with high morbidity and mortality. few papers describe blood culture isolates, underlying structural abnormalities and clinical outcomes in patients with bacteraemia. | 2007 | 18057178 |
| detection of plasmid-mediated ampc in escherichia coli, klebsiella pneumoniae and proteus mirabilis. | this study investigated the prevalence of plasmid-mediated ampc production in selected clinical isolates of escherichia coli, klebsiella species and proteus mirabilis, and compared the results of boronic acid disc screening with conventional susceptibility testing for the detection of ampc-positive isolates. | 2008 | 18057079 |
| activation of phosphatase and tensin homolog on chromosome 10 mediates the inhibition of fcgammar phagocytosis by prostaglandin e2 in alveolar macrophages. | pge2 has important inhibitory effects on the macrophage host defense functions of phagocytosis and killing, yet the molecular mechanisms involved remain to be fully elucidated. pge2 causes an elevation of camp in alveolar macrophages (ams), which in turn activates the camp effector targets, protein kinase a and the exchange protein activated by camp (epac)-1. we now report that fcgammar-induced pi3k/akt and erk-1/2 activation are inhibited by pge2 in ams. by specifically inhibiting the phosphata ... | 2007 | 18056380 |
| plasmid-mediated carbapenem-hydrolyzing beta-lactamase kpc-2 in klebsiella pneumoniae isolate from greece. | 2008 | 18056283 | |
| community-acquired liver abscess caused by serotype k1 klebsiella pneumoniae with ctx-m-15-type extended-spectrum beta-lactamase. | 2008 | 18056273 | |
| ocular pathogen or commensal: a pcr-based study of surface bacterial flora in normal and dry eyes. | to compare the bacterial population of the ocular surface of normal and dry eye subjects using conventional culture and 16s rdna pcr. | 2007 | 18055811 |
| identification of type 3 fimbriae in uropathogenic escherichia coli reveals a role in biofilm formation. | catheter-associated urinary tract infection (cauti) is the most common nosocomial infection in the united states. uropathogenic escherichia coli (upec), the most common cause of cauti, can form biofilms on indwelling catheters. here, we identify and characterize novel factors that affect biofilm formation by upec strains that cause cauti. sixty-five cauti upec isolates were characterized for phenotypic markers of urovirulence, including agglutination and biofilm formation. one isolate, e. coli m ... | 2008 | 18055599 |
| rapid detection of esbl-producing klebsiella pneumoniae in blood cultures by fluorescent in-situ hybridization. | multi-resistant enterobacteriaceae pose a serious threat of hospital acquired infections and their rapid identification is important for better clinical outcome. this study describes the rapid identification of extended-spectrum beta-lactamase-producing klebsiella pneumoniae of the sulphydryl variable-type by fluorescent in-situ hybridization. the method which rapidly identifies the target genes within 1 h could be a potentially rapid bacterial diagnostic tool. | 2008 | 18054098 |
| endogenous il-10 leads to impaired bacterial clearance and reduced survival in a murine model of chronic peritonitis. | we previously observed insufficient neutrophil accumulation and a lack of tnf-alpha response at the site of infection until bacteria numbers >10(5) colony forming units in our model of chronic murine peritonitis, suggesting a defective host response after bacterial challenge with klebsiella pneumoniae (klebsiella). the aim of this study was to determine a potentially immunosuppressive effect of il-10 in this model of chronic peritonitis. balb/c animals were injected with 10(3) colony forming uni ... | 2007 | 18053738 |
| drug sensitivity patterns of bacterial isolates from septic post-operative wounds in a regional referral hospital in uganda. | wound infections have been a problem in the field of surgery for a long time. advances in control of infections have not completely eradicated this problem because of development of drug resistance. antimicrobial resistance can increase complications and costs associated with procedures and treatment. | 2007 | 18052868 |
| [construction of novel recombinant strain harboring glycerol dehydratase reactivating factor capable of producing 1,3-propanediol]. | the dhab gene encoding glycerol dehydratase and dhag dhaf gene encoding glycerol dehydratase reactivating factor from citrobacterfreundii were amplified by pcr. the temperature control expression vector phsh harboring yqhd, dhab, dhag and dhaf gene was transformed into e. coli jm109 to yield the recombinant strain e. coli jm109 (phsh-dhab-dhag-dhaf-yqhd). the results from sds-page analysis show that the recombinant product was consistent with the molecular weight predicted from gene sequence. th ... | 2007 | 18051862 |
| detection of nitrate/nitrite bioavailability in wastewater using a luxcdabe-based klebsiella oxytoca bioluminescent bioreporter. | in the present study, we have constructed a bioluminescent bioreporter for the assessment of nitrate/nitrite bioavailability in wastewater. specifically, an approximately 500-bp dna fragment containing a nitrate/nitrite-activated nasr-like promoter (regulating expression of genes encoding nitrite reductase in the genus klebsiella) was fused upstream of the vibrio fischeri luxcdabe gene cassette in a modified mini-tn5 vector. characterization of this strain, designated w6-1, yielded dose-dependen ... | 2007 | 18051593 |
| [risk factors for the appearance of central venous catheters colonisation]. | intravascular device placement (ivd) is a part of everyday medical practice, however, its application is associated with a high risk of onset of nosocomial infections (ni) and increased mortality and morbidity. nosocomial blood infections (nbis) account for 10% of all the registered ni. nbis are more frequent in patients with a placed ivd and it present an important risk factor for the onset of nbi, i.e. catheter-associated nbis (canbis). pathogenesis of canbis is complex and conditioned by the ... | 2007 | 18050971 |
| effects of 4-chloro-2,6-bis-(2-hydroxyl-benzyl)-phenol on healing of skin wounds and growth of bacteria. | in this investigation, the effects of synthesized 4-chloro-2,6-bis-(2-hydroxyl-benzyl)-phenol (cbhbp) on cutaneous wound healing and growth of some of the wound contaminating microorganisms were studied. the antibacterial effects of this compound were then evaluated on staphylococcus aureus (s. aureus), pseudomonas aeruginosa (p. aeruginosa), escherichia coli (e. coli) and klebsiella spp., using solid dilution method. it was demonstrated that cbhbp has a significant antimicrobial activity agains ... | 2007 | 18045344 |
| effect of antibiotics in extender on bacterial and spermatozoal quality of cooled buffalo (bubalus bubalis) bull semen. | the present study was designed to study the effect of traditional antibiotic combination (streptomycin and penicillin; sp) and relatively modern combination of antibiotics (gentamycin, tylosin, lincomycin and spectinomycin; gtls) in extender on bacterial control and spermatozoal quality of liquid buffalo bull semen stored at 5 degrees c. semen collected from nili-ravi buffalo bulls (n = 10) was diluted with skim milk extender containing either sp (streptomycin 1000 microg/ml and penicillin 1000 ... | 2008 | 18042206 |
| [nosocomial infection: study of prevalence at a public teaching hospital]. | this study aimed to determine the prevalence of nosocomial infection (ni) and distribution for topography and microorganism and its antimicrobial sensibility. the study was carried out in two intensive care units (icus) of a public teaching hospital of teresina, with sampling of 394 ni cases and processed by the spss software. the respiratory infection was the biggest prevalence (61.26%) in the general icu. it was found a bigger bacterial sensibility to amicacine (52.48%) in the icu of the er. t ... | 2007 | 18041525 |