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clinical trial of bleomycin in the treatment of gestational trophoblastic disease. 200092439
serial determination of marker substances in ovarian cancer. 200092437
cutaneous manifestations of acute carbon monoxide poisoning.a patient with acute carbon monoxide poisoning due to leakage of gas from the exhaust system in his automobile noted edema and blister formation over large areas of the skin of one half of his body. rhabdomyolysis, acute but transient renal insufficiency, and hemolytic anemia developed subsequently.200092389
[clinical effects of chlormadinone acetate (cma) on human benign prostatic hypertrophy--comparative study with hexestrol by a double blind trial (author's transl)]. 197992377
ductular carcinoma of the breast: serum antibodies to tumor-associated antigens.serum antibodies to tumor-associated antigens of breast carcinoma have been studied by indirect immunofluorescence in 109 patients with breast carcinoma and 125 controls, including age/sex matched normal individuals, patients with nonmalignant disease, and patients with malignant disease other than breast cancer. we report here that sera of a large proportion of patients with ductular carcinoma of the breast have antibodies to cell surface and/or intracellular antigens of autologous tumor cells ...200092359
[5-azacytidine and new formation of purine nucleotides, rna, proteins, and lipids in the cerebral cortex of guinea pigs (author's transl)]. 197992352
isolation of plasma-membrane components from cultured human pancreatic cancer cells by immuno-affinity chromatography of anti-beta 2m sepharose 6mb.human pancreatic exocrine adenocarcinoma cells established in tissue culture expressed both hla and beta 2-microglobulin (beta 2m). plasma-membrane components of this pancreatic cancer cell line were purified from plasma membrane fractions enriched by sucrose density-gradient centrifugation, using immunoaffinity chromatography on immobilized anti-human beta 2m antibody. both rabbit and mouse monoclonal anti-beta 2m igg were used, with a 20--25-fold overall purification of 5'-nucleotidase. the me ...197992330
the antagonistic effect of dexamethasone and insulin on alpha-fetoprotein secretion by cultured h4-ii-e-c3 cells derived from the reuber h-35 hepatoma. 197992316
[analysis of the seasonal pattern of blood lead levels in relation to different concentrations of atmospheric lead].blood lead levels have been analysed in a group of people resident in turin in relation to different concentrations of lead in the atmosphere. blood samples were taken in three periods of the year corresponding to seasonal maximums of pollution. blood lead levels showed a marked decrease in the summer when the lowest concentrations are observed but the following autum sample did not show an increase. it is therefore considered likely that blood values would have been found to be increased if the ...200092298
shielding of phospholipid vesicles from phospholipase c hydrolysis by alpha-lactalbumin adsorption [proceedings]. 197992261
processing of 19 s thyroglobulin in vitro [proceedings]. 197992247
[orthosympathetic stimulation after hypercapnia in the rat].inhalation of a gas mixture : co2, 25% -- o2, 37.5% -- n2, 37.5%, provokes regularly in the light anaesthetized rat, an increase of catecholaminemia of central origin, associated with systemic arterial hypertension.197992225
esophagogastrectomy for carcinoma of the middle third of the esophagus.elective esophagogastrectomy and reconstruction by esophagogastrostomy were performed on 55 patients with malignant tumors of the midesophagus, despite invasion of contiguous structures in 60% and regional lymph node involvement in 75%. the operations were invariably palliative. two patients died within thirty days of operation. dysphagia was relieved and oral alimentation resumed in the other 53. twenty-nine patients who had experienced painful swallowing and 16 who had vomiting obtained relief ...200092220
viability assessment by dye exclusion. a fluorescent method for fungal cells.a new fluorescent staining technique for fungi utilizes the differential affinity of dead cells for rhodamine b. a mounting medium has been devised that includes the dye. this medium allows direct processing of cells from a broth and provides optimal conditions for fluorescence intensity. comparison with the standard methylene blue exclusion test as applied to the candida albicans yeast phase indicates similar specificity. various pseudohyphae and several fungi also exhibited selective uptake of ...197992216
abnormal plasma concentrations of beta-thromboglobulin in chronic myelocytic leukemia and primary thrombocythemia. 200092163
urinary proline to hydroxyproline ratio varies with age.urinary excretion of proline and hydroxyproline was studied in five groups of subjects, viz. controls, pituitary dwarfs, familial dwarfs, patients with fibrodysplasia ossificans progressive and patients with generalized scleroderma. the ratio pro/hyp in the urinary fraction precipitated with 5 parts of acetone (1 + 5 fraction) was close to one in children and youngsters in all the groups, while in adults it was higher than two. total pro/hyp does not give an accurate index of age.200092150
repair of dorsal myelomeningocele. (review of techniques). 200092125
serological cross-reactions of leptospiral lipopolysaccharide (f4) antigen.the serological specificity of leptospiral lipopolysaccharide (f4) antigen was examined by the technique of passive haemagglutination. f4 extracted from leptospiral serovars representative of several different serogroups showed wide cross reaction between serovars, including numerous one-way (non-reciprocal) reactions. the pattern of cross reaction was different to that of the standard leptospiral classification scheme.197992115
interaction of thrombin with antithrombin iii and alpha macroglobulin in the plasma. 200092072
recent state of lindane metabolism. part ii. 200092045
[the effect of cerebral perfusion pressure in cerebral infarction after occlusion of middle cerebral artery in dog (author's transl)]. 197991991
a canine model for the study of allergic asthma and suppression of hapten-specific ige antibody response. 197991961
recovery from chronic progressive polyneuropathy after treatment with plasma exchange and cyclophosphamide. 200091926
is serum total cholesterol outmoded? 200091908
intravenous immunoglobulin. 200091896
fetal iodine deficiency and motor performance during childhood.motor performance of children born to mothers living in an iodine-deficient region was assessed. the mothers were participants in a controlled trial of intramuscular iodised oil in the prevention of endemic cretinism carried out in the western highlands of papua new guinea. mothers received either iodised oil or placebo saline. children born to mothers given iodine were significantly faster and more accurate in tests of manual function than children from control mothers. the findings indicate th ...200091886
decline in hypernatraemia. 197991864
increased intracellular glutathione during penicillamine treatment for rheumatoid arthritis. 200091852
thyroid autoantibodies following external irradiation. 200091826
effect of cimetidine and ranitidine on mucosal potential difference. 200091804
ovarian overripeness and intrauterine growth retardation. 199991765
[method of obtaining a y. pestis fraction containing heterogenetic antigens]. 197991715
decreased axonal flux of retrogradely transported glycoproteins in early experimental diabetes. 197991664
further studies of the antigenic properties of h3n2 strains of influenza a isolated from swine in south east asia.h3n2 strains of influenza a isolated from swine in hong kong were compared with human strains of h3n2 influenza a variants in reciprocal hi tests using ferret sera. one isolate from swine was indistinguishable from a/hong kong/68, one set of viruses isolated in 1976 and 1977 was most related to a/hong kong/68 but was not identical to it, two isolates from 1976 were 'bridging strains' that cross-reacted equally with the contemporary variants a/victoria/3/75 and a/texas/1/77, similarly to a small ...197991663
rat liver cytosolic azoreductase. electron transport properties and the mechanism of dicumarol inhibition of the purified enzyme. 197991608
morphochemic studies on histamine and monoaminooxidase in the liver and studies on histaminolytic activity of guinea pig plasma in the course of sensitization with heterogenic protein. 197991564
fine specificity of a continuously growing killer cell clone specific for h-y antigen.h-y-specific cytotoxic t cells were first cloned in soft agar and grown over a period of 8 months in media conditioned with supernatants from mouse and rat spleen cells stimulated with concanavalin a. the specificity of cloned cells and their cytolytic potential remained essentially unchanged over the entire culture period. in addition to lysing male target cells expressing h-2db antigens, the cytolytic cells lysed also male as well as female cells expressing h-2dd alloantigens. seventeen out of ...197991527
slow potential shifts and decision p350 interactions in tasks with random sequences of near-threshold clicks and finger stimuli delivered at regular intervals. 199991496
connectivity of the auditory forebrain nuclei in the guinea fowl (numida meleagris).injection of tritiated leucine and proline into the nucleus ovoidalis of the guinea fowl (numida meleagris) produces terminal labeling in the palaeostriatum and in three adjacent zones (field l1-l3) of the auditory neostriatum (an). l2, situated between l1 and l3, receives the main input and corresponds to the former field l of rose. these neuroanatomically defined zones of the auditory neostriatum are also characterized by differing properties of their neurons. injection of radioactive material ...197991442
[retinal neovascularization: topological, morphological and hemodynamic features (author's transl)]. 199991317
the zinc-iodide-osmium technique in studies of the neurosecretory system in rats. 197991310
lymphocyte transformation in the presence of myelin basic protein in multiple sclerosis and control subjects.the transformation of lymphocytes in vitro in the presence of human myelin basic protein has been investigated in normal people, patients with multiple sclerosis (ms) and controls with other neurological diseases. there was little or no response at low concentrations (1--10 microgram/ml) but significant transformation at higher concentrations (100--1000 microgram/ml) in all three groups. there was no significant difference among the groups as a whole, but those ms patients who had had disease fo ...197991302
[studies on beta-thromboglobulin (author's transl)]. 199991290
a study of the muscle damage caused by the 7.62 nato rifle. 197991287
characterization of reverse transcriptase from filine leukemia virus by radioimmunoassay. 197991258
the association of hla--b8 with atrophic thyroiditis.one-hundred-and-forty-seven patients with autoimmune thyroiditis were studied with respect to hla antigens as they related to various clinical features. hla--b8 was found to be significantly increased among 59 patients with atrophic thyroiditis (57% vs. 26% for controls) but was identical to controls in 88 patients with goitrous thyroiditis (26%). no relation was found in either group between b8 and thyroid autoantibody titer or, in the case of goitrous thyroiditis, the rate of progression of th ...199991210
the psychological problems of the deaf and blind. 199991198
the chemistry of the brain. 197991194
cell-free synthesis and segregation of beta 2-microglobulin.beta2-microglobulin has been synthesized in vitro by using a rabbit reticulocyte lysate system and mrna from the mouse tumor cell line el4. the molecule is synthesized as a precursor with an nh2-terminal extension of 19 amino acids: ser-x-ser-val-x-leu-val-phe-leu-val-leu-val-ser-leu-x-gly-leu-tyr-x. the processing and segregation of this peripheral membrane protein are directly comparable to those of secretory proteins and integral membrane proteins: addition of dog pancreas microsomal membrane ...197991168
[efficacy of plasma substitutes of different molecular weight in acute haemorrhagic shock in dogs (author's transl)].dogs were bled into haemorrhagic shock. they were then given isovolaemic infusions of dextran 60 and 40 and of hydroxyethyl starch with an average molecular weight of 200,000 and 40,000 respectively with a view of assessing the haemodynamic efficacy of these plasma substitutes. solutions of high molecular weight hydroxyethyl starch (hes 400) were retained in the circulation for about the same length of time as was dextran 60. hes 40 (molecular weight 40,000) was retained for about 3-4 hours as m ...197991161
oxytalan fibers in peripheral odontogenic fibromas. a histochemical study of eighteen cases.oxytalan fibers, identified by histochemical methods alone, were found embedded. since oxytalan fibers have been found embedded in bone in the periodontal ligament, the finding of these fibers in the calcified material of peripheral odontogenic fibromas adds considerable weight to the assumption that these lesions are of periodontal ligament origin.199991150
large decompressive craniectomy in management of severe cerebral contusion. a review of 207 cases. 199991129
increased intracranial pressure and tentorial shear strain. 199991127
stationary potential of the brain: part i. basic studies. 197991122
human beta-thromboglobulin inhibits pgi2 production and binds to a specific site in bovine aortic endothelial cells. 197991112
[differential diagnosis between bile duct atresia and idiopathic neonatal hepatitis]. 199991099
pretreatment serum-cholesterol and response to ascorbic acid. 199991049
hexacarbon neuropathy. 199991030
retinol-binding protein in malnutrition. 199990984
rubella: which vaccine? 197990959
lymphocyte alteration by procainamide: relation to drug-induced lupus erythematosus syndrome.sera from 11 (65%) of 17 patients with newly diagnosed procainamide-induced lupus contained cold-reactive lymphocytotoxic antibodies to normal human lymphocytes in titres of 1/2 to 1/128. in contrast, only 3 of 15 patients on long-term procainamide therapy without lupus and 3 of 65 normal men had serum lymphocytotoxic antibodies, none at a titre higher than 1/2. antibody levels in the lupus patients declined quickly after procainamide was stopped, in parallel with their clinical improvement. pro ...197990917
screening for oesophageal cancer in 62 000 chinese. 199890909
leukaemia and radiation. 199890905
tardive dyskinesia. 200190894
outpatient breast biopsy. 200190891
clonidine and growth-hormone secretion. 200190890
prostacyclin and thromboxane metabolites in diabetes. 200190875
hypothalamic releasing factor for reactive depression. 200190874
enzyme immunoassays revisited. 200190867
strong association between idiopathic membranous nephropathy and hla-drw3.hla a, b, and dr antigens were determined in a homogeneous group of patients with idiopathic membranous nephropathy. the frequency of hla-drw3 was significantly higher in the patients than in a control population. the frequencies of hla b8 and b18, which are in linkage disequilibrium with drw3, were also increased.200190863
prostacyclin overproduction in bartter's syndrome.urinary excretion of 6-keto-prostaglandin f1alpha and thromboxane b2, the major metabolites of prostacyclin and of thromboxane a2, respectively, was measured by specific radioimmunoassays in five female patients with bartter's syndrome and in five normal female controls. the patients with bartter's syndrome excreted about four times as much 6-keto-pgf1alpha as the controls; their excretion of thromboxane b2 was no different from that of the controls. these data suggest that overproduction of pro ...200190861
molecular mimicry and h-ir genes. 200190854
consultant contract. 200190837
performance of blood-glucose strips. 200190828
dietary source of omega-3-eicosapentaenoic acid. 200190822
are serum-copper levels important in bleomycin therapy? 200190821
post-menopausal oestrogens protect against fractures of hip and distal radius. a case-control study.to assess the efficacy of oestrogens in preventing the common major limb fractures of postmenopausal women, retrospective case-control research was used for a new purpose--to explore beneficial rather than adverse effect of treatment. postmenopausal women admitted with fractures of the hip or distal radius and matched women admitted to the orthopaedic service for other reasons were surveyed. the "risk" of the non-oestrogen users, was estimated by inverting the customary odds ratio to calculate p ...200190802
renal-biopsy findings in lithium and prelithium patients. 200190796
lymphocyte capping and carrier detection in duchenne muscular dystrophy. 200190791
safety of postabortion sterilisation compared with interval sterilisation. a controlled study.406 women--about one-fifth of those requesting an induced abortion and sterilisation over a thirty-three-month period--volunteered to be allocated randomly to either a concurrent induced-abortion/sterilisation group or a group which was sterilised six weeks after abortion. the abortion-attributable and sterilisation-attributable complication rates of 3.8% and 5.2%, respectively, for the concurrent group did not differ significantly from the 6.7% and 6.9% rates for the interval group. the estimat ...200190768
uneasy prelude to meeting on infant feeding. 200190766
treatments for agoraphobia. 200190765
[clinical application of nk 631, a new derivative of bleomycin (author's transl)].it is impossible to accurately evaluate nk 631 as an anticancer agent from the findings only in the 7 cases; hence, the following is no more than the author's impression about the drug. however, nk 631 appeared to exert a similar anticancer effect to the currently available bleomycin. in other words, the drug will completely cure or greatly improve the early cases of squamous cell carcinoma, and bring about a transient regression in the advanced cases. the response of malignant lymphoma to this ...200190742
monoclonal antibodies: clinical potential of a growth industry. 200190739
the lorica of dinobryon. 200190737
modification of medical student perceptions of the cancer experience.social, cultural, economic, psychological, and interpersonal dimensions of cancer and cancer patient management were addressed by a diverse group of faculty in an elective course conducted for a small number of students in their second, third, and fourth years of medical school. the covert, symbolic attitudes which students held toward this disease were inferred from their scores on the beck hopelessness scale and the brief symptom inventory (bsi) prior to and at the conclusion of the course. at ...200190726
lymphocyte viability and function following ex-vivo splenic perfusions in dogs. 197990722
on the kinetics and maximal capacity of the system for rapid axonal transport in mammalian neurones.1. rabbit peroneal nerves were incubated in vitro in two-compartment chambers. step-gradients of temperature were established so that the proximal part of each nerve was slightly warmer than the distal part. after incubation, the distribution of dopamine-beta-hydroxylase (dbh) activity along the nerves was examined as an indication of the behaviour of rapid transport in adrenergic axons. 2. with temperature gradients of 5 and 8 degrees c, transport velocity in the proximal regions was expected f ...197990719
serum immunoglobulin levels in patients with neuroblastoma and their prognosis. 200190718
radiolabeling and isolation of thy-1 active glycolipids from murine brain and lymphoma cell lines. 200190698
the inhibition by xanthine phosphodiesterase inhibitors of the induction of alkaline phosphatase activity in hela cells: relationship of enzyme activity to cyclic amp concentrations.the three xanthine derivatives, caffeine, theophylline and 3-isobutyl-1-methyl-xanthine (ibmx) produced dose-dependent increases in cyclic amp concentrations in hela cells after long term treatment. only ibmx produced increases over the first 60 minutes, with a peak of approximately 5-fold control values five to 10 minutes after the addition of the drug. about four hours after the addition of either 0.67 or 1.0 mm ibmx there was a second peak in the concentration of cyclic amp which was at least ...200190681
purification of a new high activity form of glucose-6-phosphate dehydrogenase from rat liver and the effect of enzyme inactivation on its immunochemical reactivity.a new form of cytoplasmic glucose-6-phosphate dehydrogenase (e.c.1.1.1.49) was purified from rat liver by protamine sulfate precipitation, ammonium sulfate fractionation, ion exchange chromatography with diethylaminoethyl cellulose, and affinity chromatography with cibacron blue agarose and nadp agarose. this form of the enzyme has a specific activity of over 600 units/mg of protein and gives essentially a single band by polyacrylamide gel electrophoresis. the form of the enzyme isolated by this ...197990677
tobacco leaf mesophyll peroxidase. isolation, purification and some properties.two isoperoxidases, p1 and p2, were isolated from tobacco mesophyll leaves by the combined methods of ammonium sulphate precipitation, page and deae-cellulose column chromatography. the ph otpima for p1 and p2 were 7.0 and 7.5 respectively. the values of km for h2o2 were 1.82 and 0.87 mm for p1 and p2. results from this investigationsuggest that these isoperoxidases differ in their electrophoretic, catalytic and physical properties.197990669
establishment, characterization and virus expression of cell lines derived from radiation- and virus-induced lymphomas of c57bl/ka mice.permanent cell lines have been established in vitro from lymphoid tumors induced in c57bh/ka mice by fractionated x-irradiation or by inoculation of the radiation leukemia virus (radov). the cultured cells are lymphoblastic, replicate rapidly in vitro, and are tumorigenic in vivo. the cell surface markers thy 1, ly 1, ly 2,3 and gix are expressed by the lymphoid tumor cells in the mouse and persist in the corresponding cell lines; expression of the h-2 and tl antigens is greatly reduced during i ...197990660
antigens in penicillin allergy. iv. induction of ige antibody response in mice after daily treatment with contaminated but not with pure penicillin. 197990657
complement profiles in monkeys subjected to aggregate (immune complex) anaphylaxis, and following injection of soluble and particulate polysaccharides.complement profiles were established in four groups of macaca irus monkeys: (i) aggregate (immune complex) anaphylaxis was induced following immunization, with ovalbumin. upon challenge, systemic arterial pressure decreased from 115 to 50 mm hg (mean values) in 10 min. the complement profiles revealed decreases in: c1q to less than 10% of initial value within 5 min; c4 proportional to hypotension; c3 slowly to 60% at 24 h; c5, c6, c7, c8 and factor b to about 80% of initial value in 5--30 min. c ...197990656
the indirect rat mast cell degranulation test reconsidered.the indirect rat mast cell degranulation test for the detection of human reaginic antibodies was reinvestigated. when the mast cells were incubated with human reaginic serum at concentrations exceeding approximately 3%, a massive, non-specific histamine release occurred, irrespective of the presence or absence of allergen. at tolerated serum concentrations (below 3%), the allergen concentration did not influence the release process. we conclude that the indirect rat mast cell test is not applica ...197990655
characterization of the antigenic determinants of cholera toxin subunits.the antigenic specificity of purified preparations of a subunit, b subunit, alpha chain, and gamma chain of cholera toxin was studied by double immunodiffusion and radioimmunoassay with antisera produced in rabbits and mice. rabbits immunized with a subunit produced serum antibodies which were capable of binding radiolabeled a subunit, alpha chain, and b subunit. rabbits immunized with alpha chain produced serum antibodies that would bind radiolabeled alpha chain and a subunit. rabbits immunized ...197990654
[animal experimental studies on the volume expanding effect of hydroxyethyl starch 40000 in the dog acute hemorrhagic shock].after acute hemorrhagic shock in dogs the hemodynamics of hydroxyethyl starch (mw: 40,000) are studied. the experiment shows that this plasma expander has a good efficiency for 3 to 4 hours. the indications of application of this colloidal solution are discussed.197990651
endodermal sinus tumour of the ovary -- report of a case with review of literature. 200190650
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