Publications

enzymic activities of cadmium- and zinc-tolerant strains of klebsiella (aerobacter) aerogenes growing in glucose-limited chemostats.	the activities of phosphatases and some enzymes of glucose metabolism were determined in k. aerogenes ncib 418 and in two strains derived from it, resistant to 50 mug cd2+ ml-1 and 16 mug zn2+ ml-1 respectively, during growth at d = 0.38 h-1 in medium containing beta-glycerophosphate as sole phosphorus source and supplemented with cd2+ and zn2+, as appropriate, for the resistant strains. the ph-activity profiles of the phosphatases differed from strain to strain but all showed maximum activity a ...	1976	186694
adrenocorticotropin. 49.1 synthesis and biological activity of [2-delta-aminovaleric acid, 5-arginine-a1adrenocorticotropin-(2-19).	an adrenocorticotropin analogue, [2-delta-aminovaleric acid, 5-arginine]adrenocorticotropin-(2-19), has been synthesized by the solid-phase method and its biological activity has been determined. it was found that substitution of arginine for glutamic acid at position 5 of [2-delta-aminovaleric acid]adrenocorticotropin-(2-19) increased the steroidogenic potency in idolated rat adrenal cells and the lipolytic potency in isolated rat fat cells but decreased the lipolytic potency in isolated rabbit ...	1976	186605
conservatively aggressive management with bilateral wilms' tumors.		1974	186581
the effect of cyclic amp on catabolite repression of isocitrate lyase in nocardia salmonicolor (ncib9701).		1976	186557
regulation of low density lipoprotein receptor activity in freshly isolated human lymphocytes.	circulating human lymphocytes freshly isolated from venous blood of 15 normal subjects exhibited a low capacity to bind, take up, and degrade 125i-labeled low density lipoprotein (ldl). however, when these cells were incubated for 72 h in the absence of lipoproteins, they gradually acquired in increased number of high affinity cell surface receptors for ldl. the increase in the number of ldl receptors was associated with a 16-fold increase in the rate at which the cells were able to take up and ...	1976	186492
histochemistry of oxidative enzymes in experimental allergic encephalomyelitis.	the histoenzymic pattern of oxidative enzymes (g3pd, idh, sd, g6pd,hbd, nadph: dehydrogenase) was investigated in experimental allergic encephalomyelitis (eae) produced in rats according to paterson [13]. the results obtained lead to following conclusions: (1) the neuroglia, including the white matter oligodendroglia of immunized rats, exhibits increased oxidoreductase activities; (2) the neuroallergic reaction induces some stimulation of the oxidoreductive metabolism of oligoden-droglia; (3) th ...	1976	186370
measurement and partial characterization of immunoreactive glucagon in gastrointestinal tissues of dogs.	we have reported previously that increasing amounts of immunoreactive glucagon (irg), measured by four specific antisera, appeared in plasma of depancreatized insulin-deficient dogs. it was therefore concluded that pancreatectomy was not accompanied by glucagon deficiency in the dog, but instead excessive amounts of extrapancreatic irg could contribute to the diabetic syndrome. in order to locate the source of extrapancreatic glucagon, tissue extracts were assayed with anti-glucagon sera 30-k an ...	1976	186345
adenosine promoted accumulation of adenosine 3',5'-monophosphate in rabbit vagus nerve.	desheathed rabbit vagus nerve has been found to form cyclic amp when incubated with adenosine. this accumulation of cyclic amp is inhibited by theophylline but not by antiadrenergic agents, anticholinergic agents or local anaesthetics. depolarizing media are not able to promote cyclic amp accumulation in this preparation.	1976	186298
stimulation of lymphocytes by allogeneic lymphocytes and lymphoblasts in the presence of anti-hla antisera.	anti-hla alloantisera inhibit mixed lymphocyte responses in which normal lymphocytes are used as stimulator cells. these same antisera are unable to inhibit lymphocyte proliferative responses stimulated by lymphoblastoid cells from cultured lymphoid cell lines. they also fail to inhibit either the generation of cytotoxic effector cells by lymphoblastoid cells or lymphocyte-mediated cytotoxicity against the lymphoblasts. although the number of hla antigens on the surface of lymphoblasts is report ...	1976	186270
dose-related sleep disturbances induced by coffee and caffeine.	in a 13-night sleep laboratory study, each of 18 normal young adult males twice received 1 cup of warm water, 1-, 2-, and 4-cup equivalents of regular coffee, a 4-cup equivalent of decaffeinated coffee, and a 4-cup equivalent of caffeine. all beverages were administered 30 min before bedtime according to a balanced latin-square design. regular coffee produced dose-related changes in most standard electroencephalogram-electrooculogram (eeg-eog) sleep parameters, and the 4-cup equivalents of regul ...	1994	186223
exocrine pancreas under experimental conditions. ii. in vitro formation of paracrystalline structures and its functional consequences.	the in vitro formation of paracrystalline structures after addition of high concentrations of amino acids to the incubation medium was investigated in pancreatic lobules and pancreatic homogenates. it could be shown that even in the homogenate, pcpa induced the formation of paracrystalline structures which exhibited the same ultrastructural arrangement as seen in the in vivo induced paracrystalline inclusions in the rer of the rat pancreas. in correlation with the morphological alterations, the ...	1976	186191
nucleotide sequence study of mouse 5.8s ribosomal rna.	the primary structure of 5.8s mouse ribosomal rna has been studied and compared to the structures previously established for other animal species. the results obtained show that mouse 5.8s ribosomal rna yields pancreatic oligonucleotides with the same nucleotide sequence as the homologous oligonucleotides from rat cells. furthermore t1 oligonucleotides of 5.8s ribosomal rna from rat, mouse and human cells behave identically on fingerprinting fractionation and have the same composition as judged ...	1976	186131
chirality of the hydrogen transfer to nad catalyzed by myo-inositol dehydrogenase from klebsiella pneumoniae.	chirality, hydrogen transfer, myo-inositol dehydrogenase. the chirality of the hydrogen transfer to nad catalyzed by myo-inositol dehydrogenase (myo-inositol: nad 2-oxydoreductase, ec 1.1.1.18) from klebsiella pneumoniae (formerly classified taxonomically as aerobacter aerogenes or kleb siella aerogenes) was investigated. [4-3h] nad was enzymatically reduced to [4-3h] nadh with non-labeled myoinositol and myo-inositol dehydrogenase. the stereochemistry of the prochiral center at c4 of the nadh p ...	1976	185832
[idiopathic pulmonary hemosiderosis. apropos of 1 case].	idiopathic pulmonary hemosiderosis gives rise to anemia, due to repeated intra-alveolar hemorrhage, the reabsorption of which leads to hemosiderin deposits in the lung parenchyma. the authors report a case in a young woman aged 24 years whose illness started with anemia, then two months later, with hemoptysis and a broncho-pulmonary syndrome with a low grade fever. on the 6th month, there occurred a hazy infiltrate of both lung bases which was fleeting, mobile and recurrent. in the light of this ...	1982	185718
adenomatous polyps in the stomachs of hatchery-grown salmonids and other types of fishes.		1982	185653
opiate receptor: autoradiographic localization in rat brain.	opiate receptor sites in rat brain can be labeled in vivo by [3h]diprenorphine, a potent opiate antagoinst. using techniques to minimize diffusion in fresh, frozen, unfixed brain, we have localized [3h]diprenorphine by autoradiography to visualize the distribution of opiate receptors. silver grains indicative of the binding of labeled [3h]diprenorphine are discretely localized in numerous areas of the brain with very high densities in the locus coeruleus, the substantia gelatinosa of the spinal ...	1976	185626
novel structure at 5'-ends of nascent dna chains.	because of their association with protein short nascent dna chains in escherichia coli can be separated from other cellular dna by chromatography on hydroxylapatite. protein-free dna chains of less than 500 nucleotides in length are resistant to degradation from the 5'-end by alkaline phosphatase [orthophosphoric-monoester phosphohydrolase (alkaline optimum); ec 3.1.3.1] and spleen phosphodiesterase (oligonucleate 3'-nucleotidohydrolase; ec 3.1.4.18). in contrast, dna chains containing more than ...	1976	185611
effects of (+)-tubocurarine on neuromuscular facilitation and depression in rat diaphragm.		1976	185539
the distribution of plasma lipoproteins in middle-aged male runners.	stimulated by increasing evidence of an inverse relationship between plasma high-density lipoprotein cholesterol level and frequency of coronary heart disease, we determined concentrations of fasting plasma cholesterol, triglyceride, and lipoproteins in 41 very active men (running greater than 15 miles/wk for the previous year) 35-59 years of age (mean age, 47) and in a comparison group of men of similar age, randomly selected from three northern california communities. the runners had significa ...	1984	185487
enumeration of antigen reactive t cells against sheep erythrocytes by the virus plaque assay.		1976	185443
demyelinative myelopathy in mice induced by the da virus.	an attenuated tissue culture adapted strain of da virus, an agent related to the theiler murine encephalomyelitis viruses (tmev), was used to induce a chronic myelopathy in mice. spastic paraparesis first appeared 5 months after weanings were inoculated intracerebrally with the virus. none died as a direct result of the infection, and none improved once paretic. the major pathological change in these mice was demyelination of thoracic segments of spinal cord. no clinical illness or demyelinative ...	1976	185333
normal rabbit alveolar macrophages. ii. their primary and secondary lysosomes as revealed by electron microscopy and cytochemistry.	in this investigation, vacuoles containing tubular myelin proved to be digestive compartments with cytochemical reactivity for acid phosphatase and arylsulfatase. these cytochemical markers identify the secondary lysosomes, known to contain enzymes capable of hydrolyzing phospholipids like surfactant. therefore, it appears that alveolar macrophages possess the enzymatic machinery for the degradation of the tubular myelin found in their digestive vacuoles. although it thus appears evident that al ...	1976	185318
inter- and intralaboratory variability in antibiotic susceptibility tests with pseudomonas aeruginosa and enterobacteriaceae.	a two-phase collaboratice study was designed for definition of the extent to which results of disk diffusion tests can be reproduced. two currently recommended techniques, the kirby-bauer method and the agar overlay method, were used. of special concern were tests of pseudomonas aeruginosa with moderate susceptibility to carbenicillin; gentamicin, tobramycin, polymyxin b, and colistin were also tested with p. aeruginosa as well as with klebsiella pneumoniae, escherichia coli, and proteus species ...	1976	185302
chirality of the hydrogen transfer to the coenzyme catalyzed by ribitol dehydrogenase from klebsiella pneumoniae and d-mannitol 1-phosphate dehydrogenase from escherichia coli.	the stereochemistry of the hydrogen transfer to nad catalyzed by ribitol dehydrogenase (ribitol:nad 2-oxidoreductase, ec 1.1.1.56) from klebsiella pneumoniae and d-mannitol-1-phosphate dehydrogenase (d-mannitol-1-phosphate:nad 2-oxidoreductase, ec 1.1.1.17) from escherichia coli was investigated. [4-3h]nad was enzymatically reduced with nonlabelled ribitol in the presence of ribitol dehydrogenase and with nonlabelled d-mannitol 1-phosphate and d-mannitol 1-phosphate dehydrogenase, respectively. ...	1976	185137
the secretion of lysosomal enzymes.	the studies reviewed in this chapter provide further evidence that the secretion of lysosomal enzymes and other hydrolases is a constitutive function of certain cells whereas in other cells is an inducible process probably contributing to the pathology of a variety of diseases. little is known of the mechanisms mediating the secretion of lysosomal enzymes. we have summarized evidence suggesting a role of microfilaments and microtubules in controlling enzyme release, but further studies of the bi ...	1976	185100
naltrexone-induced hypothermia in the rat.	naltrexone, in relatively high doses, has been reported to cause a fall in body temperature in human ex-heroin addicts who had been abstinent for at least 6 weeks. the underlying mechanism of this hypothermic effect has been investigated in rats. the first consideration was that the temperature change was a reflection of delayed withdrawal but rats implanted with a morphine pellet 45 days earlier showed no significant change in temperature after a dose of naltrexone that caused marked withdrawal ...	1976	185061
a comparison of cytochrome c from macrobrachium malcomsonii with other invertebrate cytochromes c.		1983	185001
biokinetics of galactose in the homozygotes and heterozygotes of both forms of galactosemia.	41 heterozygoes and 4 homozygotes with a deficiency of galactose 1-phosphate uridyl transferase and also 3 heterozygotes and 1 homozygous patient with galactokinase deficiency were subjected to intravenous galactose loading tests with a dose of 350 mg/kg body weight in order to answer the question whether it is possible to detect the heterozygotes of both types of galactosemia by this method. for comparison, 38 healthy children and adolescents, 24 children with epidemic hepatitis and 4 children ...	1983	184990
electron spin resonance study of the synaptosome opiate receptor: kinetics of stereospecific binding of spin labeled morphine.	morphine, spin labeled on the 3- or 6-position has been used as the opiate ligand in a study of the time course of stereospecific opiate binding to intact synaptosomes isolated from non-cerebellar rat brain. the broadening of electron spin resonance lines induced by immobilization of the ligand on binding has been used to determine the concentration of bound opiate. the stereospecificity of the reaction was measured by comparing ligand binding in the presence of thousand-fold molar excesses of d ...	1976	184858
the induction of tumour cell adhesiveness and intercellular junctions by a glycoprotein of rat ascites hepatoma cell surface.	rat ascites hepatoma ah109a cells (present as a free form in vivo) can aggregate and then develop well-defined tripartite junctional complexes, including intermediate junctions, desmosomes and focal tight junctions, on incubation with a glycoprotein separated from rat ascites hepatoma ah136b cells (forming cell islnds in vivo). the development of binding structures was strongly inhibited by actinomycin d. ah109a cells or rat ascites hepatoma ys cells (present as a free form in vivo) previously t ...	1976	184812
substrate cycles in metabolic regulation and in heat generation.	1. the presence of substrate cycles in tissues has been demonstrated by direct isotope methods in recent years. this demonstration has provided the impetus for a reappraisal of the roles of substrate cycling in metabolic regulation and in heat production. these aspects of substrate cycling are discussed in this paper. the relationship between near-equilibrium reactions and substrate cycles is emphasized, since this provides a basis for the derivation of a function describing in precise quantitat ...	1976	184791
differential responding to the beta movement after waking from rem and nonrem sleep.	ten young adults were wakened from rem sleep and from nonrem sleep on two nonconsecutive nights and were tested to determine their upper and lower beta-movement thresholds. the ranges of the illusion were found to be significantly wider after waking from rem sleep than after waking from nonrem sleep or before sleep. the differential responding to the beta movement supports the experimental hypothesis that apparent motion may provide sensitive detectors of the operation during wakefulness of the ...	1983	184716
aspects of the influence of parasympathetic stimulation on aqueous humour dynamics in the rabbit [proceedings].		1975	184666
an electronic device for pupillary measurement [proceedings].		1983	184650
[relation between the biochemical effects of alcohol and the development of alcoholic liver disease].		1990	184562
[allergic manifestations in acute respiratory viral infections in children].		1990	184417
persistence of antibody to feline panleucopaenia induced by a modified live virus vaccine.		1976	184348
reduction in acetylcholine sensitivity of axotomized ciliary ganglion cells.	1. isolated cell clusters from ciliary ganglia of 3- to 4-day-old chickens were used to examine the electrical characteristics and sensitivity to iontophoretically applied acetylcholine (ach) of normal cells and cells that had been axotomized on the day of hatching. 2. resting potentials, input resistances and capacitances were the same in axotomized cells as in normal cells. these averaged about 70 mv, 165 momega and 35 pf respectively. 3. sensitivity to iontophoretically applied ach was lower ...	1976	184272
susceptibility of "enterobacteria" to aminoglycoside antibiotics: comparisons with tetracyclines, polymyxins, chloramphenicol, and spectinomycin.	strains of enterobacteria, including common, aerobic, pathogenic gram-negative bacilli, and enterococci were tested for susceptibility to 11 aminoglycoside antibiotics by a twofold agar-dilution method with an inocula replicator. for comparison, similar tests were done with seven tetracycline analogues, two polymyxins, chloramphenicol, and spectinomycin. tobramycin compared favorably with the more active aminoglycosides, with some exceptions related to individual strains of species. the tetracyc ...	1976	184213
the histopathology of trophoblastic tumours.		1989	184114
protection by propylthiouracil against carbon tetrachloride-induced liver damage.	rats given a single intragastric dose of carbon tetrachloride (ccl4), 0.25, 0.50, or 1.0 ml per kg) showed a dose-dependent increase in sgot, serum ornithine carbamyltransferase, and liver necrosis (graded histologically as 0 to 4+) 24 hr after the treatment. daily intubation with propylthiouracil (ptu) for 10 days in doses of 5 to 50 mg per kg significantly reduced the elevation of sgot activity, completely suppressed the serum ornithine carbamyltransferase changes, and reduced the degree of ne ...	1976	184009
comparative studies on mitochondrial coupling factor b and fb.		1976	183765
significance of specific transplantation antigen expression at the surface of papovavirus sv40-infected permissive cells.		1982	183734
pancreatic islet cell tumors: a brief review.		1991	183636
actions and interactions of theophylline and imidazole on cardiac contractility, phosphorylase activation and cyclic amp.	injection of 1.0 mg theophylline and 1.6 mg imidazole into guinea-pig hearts perfused by the langendorff technique increased cardiac contractile force by 20.0 +/- 1.0% and 23.3 +/- 1.2% over control and activated phosphorylase without producing significant changes in cyclic amp levels. when guinea-pig hearts were perfused with theophylline (10(-3) m) or imidazole (20 mm), injection of either imidazole or theophylline did not further increase cardiac contractility or phosphorylase a levels. in al ...	1976	183614
persistence of virus-specific igm and clinical recovery after japanese encephalitis.	we have searched for evidence of a chronic japanese encephalitis virus (jev) infection in six thai patients convalescing from acute japanese encephalitis (je) in whom jev-specific igm antibody was last detected 116 to 350 days after their acute illness. these six patients were compared with 94 other je patients matched for age, sex and serological response and in whom jev-specific igm was either short-lived (less than 90 days) or not tested. all patients were evaluated for the presence or absenc ...	1976	183556
polynucleotide sequences common to the genomes of simian virus 40 and the human papovaviruses jc and bk.		1976	183358
letter: isolation and characterisation of equine herpes virus type 1.		1976	183339
positive differential heterophile antibody test. persistence in a symptomatic patient.	a patient who had documented mononucleosis in june 1971 has been persistently symptomatic since that time, with easy fatigability and weight loss. he has also had a positive differential heterophile antibody test for mononucleosis for 14 months. although no evidence for active estein-barr virus (ebv) infection was discovered, the possibility of a chronic ebv infection is discussed.	1976	183027
the biochemistry of sugars.	in animal cells the utilization of sugars involves one or more of the three major pathways known to occur in these cells. the glycolytic (embden-meyerhof) pathway is quantitatively the most important, and this pathway, coupled to the citric acid cycle, serves as a major source of energy. glycolysis and the citric acid cycle also provide most of the precursors for the synthesis of proteins, nucleic acids and lipids. the pentose phosphate, or hexose monophosphate oxidation, pathway is a major sour ...	2003	182650
[melanotic progonoma. report of two cases (author's transl)].		2003	182628
in vitro trophic action of acth and insulin upon adrenocortical enzymes of the squaliform elasmobranch ginglymostoma cirratum (bonnaterre).		2003	182612
the stimulatory effect of hypothalamic and mesencephalic tissue on the interrenal of tadpoles of xenopus laevis daudin.		1976	182611
individual consistency in behavioral states in neonates.	in this study we identified consistent characteristics of the sleep-wake state of newborn infants. forty-one normal, full-term infants were observed in a warmer-skin temperature maintained at 36.1 degree c--located in a sound-attenuated room for 1 hr during 2 successive mid-feeding periods. the infant's state was recorded on a check-list every 10 sec using the following categories for sleep and wakefulness: quiet sleep a, quiet sleep b, active sleep without rem, active sleep with rem, active sle ...	2003	182605
preliminary results with an oral application of killed purtussis bacteria in newborn infants.	newborn babies have been vaccinated orally on five consecutive days, with 5 droplets of a vaccine containing 10(11) killed bordetella pertussis. eight out of twelve subjects showed antibody titres varying between 1:20 and 1:80.	1976	182603
effectiveness of orally administered bordetella pertussis vaccine in mice.	oral administration of killed bordetella pertussis organisms to mice results in increased resistance to an intracerebral infection with virulent b. pertussis cells. the rate of survival is dependent on the dose of antigen. but besides specific systemic immunity, which is persistent over a long period, also transient non-specific resistance is increased. these effects are evidently induced without penetration of bacterial substances into the circulation.	1976	182602
properties and partial purification of an oestrogen receptor from neonatal rat brain.		1976	182324
[adsorption of enteroviruses on nitrate cellulose membranes: influence of mineral salts, detergents and calf serum (author's transl)].	the filtration through cellulose nitrate membranes of a poliovirus type ii suspension in distilled water alone or with added mineral salts (nacl, mgcl2, alcl3) results in adsorption of the virus. the maximal adsorption is obtained with nacl. a detergent in the virus suspension or a pretreatment of the membranes with calf serum prevents this adsorption. elution of the adsorbed enteroviruses is achieved with alcaline and proteinaceous buffer.	1976	182051
enzootic with ectromelia symptomatology in sprague-dowley rats.		1976	181904
[application of scanning electron microscopy in the evaluation of iron content of human synovial membrane].		1976	181851
a protein-binding assay for direct determination of adenosine 3',5'-monophosphate in amniotic fluid, cerebrospinal fluid, plasma, and urine.	an adenosine 3',5'-monophosphate (cyclic amp)-binding protein was isolated from bovine skeletal muscle. this preparation showed maximum binding capacity for cyclic amp at the physiological ph of amniotic fluid, cerebrospinal fluid, and plasma and had a high association constant of 1.4x10(9) 1/mol. this preparation of binding protein, together with albumin and edta in the assay buffer, gave a sensitive and specific competitive protein-binding assay that permitted direct determination of cyclic am ...	1976	181838
an unusual upper abdominal gas pattern.	the case history of one patient is discussed to illustrate radiographic features, etiology and prognosis of gas bubbles in the gastric wall.	1981	181780
fetal lung maturation iv: the release of phosphatidic acid phosphohydrolase and phospholipids into the human amniotic fluid.	the relationship between surface active material and phosphatidic acid phosphohydrolase (papase) activity was examined in human amniotic fluid after centrifugation at 105,000 x g for one hour. the distribution of papase activity between the pellet and supernatant fractions was similar to that of phospholipids in the amniotic fluid. the majority of the papase activity was found to be associated with the pellet fraction. similarly, 82% of the phospholipid was also present in this fraction. of the ...	1976	181724
[radioimmunological determination of plasma acth and beta-msh in congenital adrenal gland hyperplasia].		1981	181667
delayed clearance of chylomicron remnants following vitamin-a-containing oral fat loads in broad-beta disease (type iii hyperlipoproteinemia).	chylomicron "remnants" are formed by the selective removal of triglyceride catalyzed by lipoprotein lipase. to investigate a possible defect in the clearance of these remnants in the pathophysiology of broad-beta disease (type iii hyperlipoproteinemia), subjects with this disorder and comparison subjects with endogenous hypertriglyceridemia (and type iv lipoprotein patterns) ingested an oral fat load (corn oil: cocoa butter, 1:1, 50 g/sq m) containing retinyl ester, 100 mg, with or without 15 mu ...	1981	181657
neoplasia at the site of ureterosigmoidostomy.	an increased incidence of neoplasia at the site of ureterosigmoidostomy must be considered in patients being evaluated for or who have undergone this procedure. a case of mucinous adenocarcinoma 24 years following bilateral ureterosigmoidostomy is reported. this patient had bilateral hydroureteronephrosis, which led to left nephroureterectomy and right cutaneous ureterostomy. mucinous adenocarcinoma was diagnosed only after the edematous, protruding and inflamed cutaneous ureterostomy stoma was ...	1981	181600
dysmyelination in the sciatic nerves of dystrophic mice.	ultrastructural alterations were observed in the sciatic nerve of dystrophic mice. myelin sheaths were abnormal in shape, abruptly ceased beyond a node of ranvier, leaving the axon naked. these changes were seen in both afferent and efferent nerve fibres. apparent embryonal schwann cells and schwann cells which were associated with increased lysosomes in the cytoplasm were observed in the proximal portion. there is a relative decrease in schwann cells in the cross-section of the radicular parts, ...	1981	181540
toluene diisocyanate (tdi) pulmonary disease: immunologic and inhalation challenge studies.	clinical and serologic effects of tdi exposure were studied in 112 occupationally exposed plant workers. sera were obtained before and after commencement of tdi production. all subjects were skin-tested with common inhalant allergens and a tdi-hsa conjugate. total eosinophil counts, immunoglobulin quantitations, and specific antibody assays by pca, p-k, and radioimmunoassay were performed. clinically "sensitive" individuals were tested by provocative inhalation challenge with from 0.005 ppm to t ...	1981	181412
in vivo activation by polymyxin b of phospholipase from pseudomonas aeruginosa and escherichia coli.		1976	181357
fine structural analysis of rabbit synovial cells. ii. fine structure and rosette-forming cells of explant and monolayer cultures.	the fine structure and plasma membrane receptors of explant and monolayer cells of normal rabbit synovium were studied. in explants about 10% of the cells were round and formed rosettes with igc and c3 markers, whereas the remaining cells were stellate, resembled young fibroblasts, and had no receptors for igg and complement. monolayer cells looked like fibroblasts, produced fine extracellular fibrils and hyaluronate, and formed no rosettes. thus early cultures contain both macrophages and fibro ...	1976	181009
stimulation of glycogenolysis and gluconeogenesis by epinephrine independent of its beta-adrenergic function in perfused rat liver.		1976	181007
isolation of pseudomonas aeruginosa and other bacterial species from ornamental aquarium plants.	ornamental aquarium plants were demonstrated to carry as many as 10(8) viable mesophilic bacteria per g. gram-negative organisms predominated among the 19 genera of bacteria identified. pseudomonas aeruginosa was readily isolated from 53% of the samples tested.	1976	180888
inorganic medicinal chemistry.		1986	180633
changing patterns of surgery of the gallbladder, bile ducts, and liver.		1986	180618
[epidemiological aspects of cytomegalovirus infections].		1975	180573
[i. evaluation of the hypothalamo-hypophyseal-adrenal function. effects of the administration of acth, dexamethasone, metopirone and l-dopa on the steroids of urine in normal patients].		1986	180569
ammonium sulfate activation of phosphodiesterase in homogenates of larvae of the european corn borer.	european corn borer phosphodiesterase is highly activated by (nh4)2so4 and moderately activated by nh4c1 (ph 7.6, 33 degrees). vertebrate and crayfish diesterases, on the other hand, are inhibited by (nh4)2so4. it is likely that (nh4)2so4 causes some configurational change in the european corn borer phosphodiesterase molecule which results in the exposure of more active sites and hence greater enzyme activity. in in vitro tests caffeine (0.008 m) and theophylline (0.008 m) inhibit phosphodiester ...	1976	180541
experimental alterations in cyclic adenosine monophosphate concentrations in the cat basilar artery.	levels of cyclic adenosine monophosphate (amp) in the basilar artery and in circulating blood of cats were determined after the production of spasm by topical application of blood to the vessel and following treatment with agents known to alter cyclic amp. isoproterenol, known to stimulate adenyl cyclase, and aminophylline, a phosphodiesterase inhibitor, were studied alone and in combination. cyclic amp of the basilar artery fell from a mean control value of 43 to 26 pmoles per milligram of prot ...	1976	180456
initiation sites of rous sarcoma virus rna-directed dna synthesis in vitro.	rous sarcoma virus dna synthesis in disrupted virions is initiated mainly at a site about 200 nucleotides or less from the 5' terminus, but other initiation sites throughtout the rna seem to be used as well. no aug triplet occurs within a 5' terminal segment of about 25 nucleotides.	1976	180433
[polyphosphate biosynthesis in rhodospirillum rubrum chromatophores].	the chromatophores of rhodospirillum rubrum were found to synthesize in the light not only atp and pyrophosphate but also high molecular weight polyphosphates. biosynthesis of all studied compounds was inhibited by antimycin a, an inhibitor of the electron-transport photosynthetic chain. synthesis of high molecular weight polyphosphates is stimulated, while that of pyrophosphate is inhibited, in the conditions providing intensive synthesis of atp (in the presence of adp and in the absence of oli ...	1976	180387
uptake of circulating iron by the duodenum of normal mice and mice with altered iron stores, including sex-linked anemia: high resolution radioautographic study.	using electron microscopy radioautography, the deposition of intravenously administered iron in the duodenal epithelium was studied in normal mice, iron-overloaded and iron-deficient mice, and in mice with x-linked anemia (gene symbol sla) 4 and 24 hours after injection of 59fe. the resolution of radioautography with 59fe was determined with a line source and the distance from the hot line within which half of the grains fell (hd value) was 1650 a. in normal, iron-overloaded, and sla mice, radio ...	1985	180329
[surgery of cerebellar glioma].		1985	180308
the cleavage of polyoma virus dna by restriction enzymes kpni and psti.	the action of two restriction endonucleases on polyoma virus dna has been examined and the sites at which they cleave the dna located. one of the enzymes, kpni from klebsiella pneumoniae ok8, cleaves polyoma dna twice at about 11-6 and 59-2% from the ecori site. the other enzyme, psti from providencia stuartii 164, cleaves polyoma dna five times at about 14-8, 16-5, 32-6, 50-3 and 80-0% from the ecori site. some of the cleavages produced by these enzymes alone, or in conjunction with other endon ...	1976	180247
benign mixed tumour of heterotopic salivary gland tissue in upper neck. report of a case with a review of the literature on heterotopic salivary gland tissue.	a case of benign mixed tumour arising in ectopic salivary gland tissue of the mucous type is described. the tumour was located at the angle of the right mandible, in the upper middle third of the neck, along the anterior border of the sternomastoid muscle. this observation is substantiated by a pathomorphological study. a comprehensive review of the world literature on heteroptic salivary gland tissue has also been carried out, together with a search of the possible pathogenesis which seems to b ...	1985	180218
experimental encephalitis caused by herpes simplex virus: comparison of treatment with tilorone hydrochloride and phosphonoacetic acid.	a mouse model of encephalitis caused by herpes simplex virus was used to compare the antiviral activity of tilorone hydrochloride with that of phosphonoacetic acid. these compounds were also administered simultaneously to determine whether the combination had a synergistic effect. rates of survival and concentrations of virus in brain were used as criteria for judging the effectiveness of treatment. the fatal course of encephalitis was not altered by any treatment protocols in which tilorone hyd ...	1976	180204
study of title 19 (medicaid) coverage of sterilization.		1985	180077
stimulation of ornithine decarboxylase synthesis and its control by polyamines in regenerating rat liver and cultured rat hepatoma cells.	ornithine decarboxylase has been induced in log phase hepatoma cells grown in suspension culture. induction with n6, o2'-dibutyryl cyclic adenosine 3':5'-monophosphate produced a 4-fold increase in enzyme activity by 3 hours which was followed by a return to base levels by 6 hours. induction with dexamethasone, a potent synthetic glucocorticoid, exhibited a slow steady rate of increase in enzyme activity, reaching a plateau level of approximately 5- to 6-fold stimulation by about 12 hours. indu ...	1976	180026
nad+-malic enzyme. regulatory properties of the enzyme from ascaris suum.	the regulatory properties of the nad-dependent malic enzyme from the mitochondria of ascaris suum have been studied. the malate saturation curve exhibits sigmoidicity and the degree of this sigmoidicity increases as the ph is increased. fumarate was the only compound tested that stimulated the enzyme activity, whereas oxalacetate was the most powerful inhibitor. activation by low levels of fumarate was found to be competitive with malate. it is proposed that this stimulation has physiological si ...	1976	180002
the link between charge separation, proton movement and atpase reactions.		2003	179861
[changes in the functional state and structure of the adrenals in cc14 poisoning].	introduction of cci4 in doses of 0.1 and 0.2 ml/100 g to albino rats reduced the steroid production generated by adrenal sections. in 24 and 48 hours after poisoning with a small dose of cci4 (0.1 ml/100 g) there could be seen an increased concentration of 11-oxycorticosteroids in the plasma. morphological signs of a damage suffered by the gland were observed only in poisoning with a large dose of cci4 (0.2 ml/100 g).	1975	179852
plastocyanin: possible significance of quaternary structure.	some properties of the blue copper protein plastocyanin from the green alga scenedesmus have been investigated and compared with that from spinach, including amino acid composition, isoelectric point and copper content. the protein from scenedesmus contains two, that from spinach four copper atoms per molecular weight of 40000. a combination of sodium dodecylsulfate/polyacrylamide gel electrophoresis and quantification of sulfhydryl groups indicates a strong preference for a species composed of ...	2003	179807
steroid production by quartered and capsular rat adrenal gland in response to haemorrhage.	60 min after rapid bleeding (1.5--2.0 per cent of b. w.) both aldosterone and corticosterone production rate by quartered rat adrenals were found to be elevated. however, no difference was observed in the rate of aldosterone and corticosterone production by capsular adrenals of sham operated and hypovolaemic rats. corticosterone production rate by decapsulated adrenals was much more higher after haemorrhage than in the control group. the same alterations could be observed incubating adrenal tiss ...	1975	179800
daily variation in concentration of plasma corticosteroid in hypophysectomized rats.	a daily variation in the concentration of plasma corticosteroid hormone is present in hypophysectomized rats implanted with pellets of adrenocorticotropic hormone (acth) and thyroxine. although acth is necessary to maintain a functional adrenal, and thyroxine is required to permit the expression of the plasma corticosteroid rhythm, a normal daily variation in plasma corticosteroid concentration does not appear to depend on the periodic release of pituitary hormones.	1976	179796
properties of the low-temperature photosystem i primary reaction in the p-700-chlorophyll alpha-protein.	the photosystem i primary reaction, as measured by electron paramagnetic resonance changes of p-700 and a bound iron-sulfur center, has been studied at 15 degrees k in p-700-chlorophyll alpha-protein complexes isolated from a blue-green alga. one complex, prepared with sodium dodecyl sulfate shows p-700 photooxidation only at 300 degrees k, whereas a second complex, prepared with triton x-100, is photochemically active at 15 degrees k as well as at 300 degrees k. analysis of these two preparatio ...	1976	179589
detection of type-specific antibody to herpes simplex virus type 1 and 2 in human sera by complement-fixation tests.	type-specific antigens for herpes simplex virus type 1 and 2 were prepared by rigorous absorption of cell extracts with heterotypic immune sera. type-specificity was demonstrated by immunodiffusion and complement-fixation tests against immune sera prepared in rabbits. specific type 1 complement-fixing reactivity was detected in eleven of fifteen sera from roman catholic nuns and in two convalescent sera from patients with recurrent herpes labialis; these sera had been previously shown to contain ...	1976	179502
optic nerve manifestations of human congenital cytomegalovirus infection.	a latin american male and a white female infant who had a cytomegalovirus infection on the first day of life had unilateral optic nerve hypoplasia. a white male infant who had cytomegalovirus isolated at 5 weeks of age had a unilateral partial coloboma of the optic nerve. a 4-month-old black infant with cytomegalovirus infection diagnosed at 2 days of age had a unilateral complete coloboma of the optic nerve associated with microphthalmia. optic nerve involvement was an important manifestation o ...	1976	179325
the influence of some dietary factors and/or treadmill exercise on rat and chicken tissue lipids and serum lipoproteins.	four different experiments, one with cockerels and three with rats, are described which relate to the effect of dietary factors and/or exercise on serum and liver lipids as well as on serum lipoproteins. several classes of lipoproteins were isolated by preparative ultracentrifugation, and their purity assessed by gel electrophoresis. the lipid composition and protein content of serum lipoproteins and tissue were also determined. dietary cholesterol produced an enormous increase (200 fold) in ser ...	1976	179301
[bilateral tumors of the parotid glands. (author's transl)].	bilateral parotid tumors occur very rarely; they account for 0.5% of 544 cases of parotid tumors recorded at the national cancer institute of milan from 1945 to 1974. three cases of bilateral tumors are described; two tumors were synchronous and one metachronous. the patients were women of 51, 46 and 52 years. the histologic type was the same on both sides in all cases, namely adenolymphoma, mucoepidermoid carcinoma and mixed tumor respectively. surgical exicston was the treatment of choice; acc ...	1997	179172
lipids of klebsiella pneumoniae: the presence of phosphatidyl choline in succinate-grown cells.	the carbon and energy source for aerobically grown cultures of klebsiella pneumoniae profoundly influenced the total lipid content and phosphatide composition. glucose-grown cells contained 13% lipid, 56% of which was phospholipids. succinate-grown cells contained 8% lipid, 66% of which was phospholipids. the predominant phosphatides of glucose-grown cells were phosphatidyl ethanolamine, 82%; phosphatidyl glycerol, 4.5%; phosphatidic acid, 5%; cardiolipin, 6.5%; phosphatidyl serine; and trace am ...	1976	178973
mental health consultation with public health nurses, using transactional analysis as a tool.		1997	178858