Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
|---|
| [investigation of microbial colonization of computer keyboards used inside and outside hospital environments]. | computers have been commonly used in daily life and at hospitals by medical staff. this study was carried out to search the microbial colonization of computer keyboards and mice used inside and outside hospital environments. keyboards and mice samples from a total of 398 computers were included to the study, in which 38 were used by doctors and nurses in the hospital clinics (group 1); 32 by the medical faculty students (group 2), and 328 by university students (group 3) in the computer laborato ... | 2008 | 18697431 |
| [evaluation of the epidemiological, clinical and laboratory findings in continuous ambulatory peritoneal dialysis related peritonitis attacks]. | the aims of this study were to assess epidemiological features, clinical outcomes, laboratory findings, causative organisms and treatment approach for continuous ambulatory peritoneal dialysis (capd) -related peritonitis cases. a total of 50 patients (35 male, 15 female; age range: 18-83 years, mean age: 49 +/-17 years) with capd related peritonitis treated in infectious diseases and clinical microbiology department of ankara training and research hospital between february-july 2006 were enrolle ... | 2008 | 18697423 |
| [etiologic agents and risk factors in nosocomial urinary tract infections]. | nosocomial urinary tract infection (nusi) is one of the most common hospital acquired infections. in this study, we aimed to determine the risk factors, frequency and the bacterial etiology of nusi in hospitalized patients at trace university hospital, turkey. between september 1st 2004 to march 1st 2005, 104 nusi episodes from 91 adult patients (mean age; 60.8 +/- 16.1 years; 46 were female) were determined among 8704 patients admitted to the hospital. during the study period, cumulative incide ... | 2008 | 18697422 |
| [in vitro activity of tigecycline against multiple resistant acinetobacter baumannii and carbapenem resistant klebsiella pneumoniae isolates]. | in order to detect the in vitro activity of tigecycline against multiple resistant gram-negative bacilli isolated in our hospital, tigecycline susceptibilities of clinical isolates of multiple and/or panresistant 100 acinetobacter baumannii isolates, and 38 carbapenem resistant klebsiella pneumoniae (17 of which were panresistant), obtained between january 2005 and august 2007, were evaluated by using e-test (ab biodisc, sweden). carbapenem resistance rate was found to be 59% for a.baumannii, us ... | 2008 | 18697418 |
| extended spectrum beta lactamase (esbl) producing escherichia coli and klebsiella pneumoniae in diabetic foot infection. | 2008 | 18695337 | |
| a maldi tof ms-based minisequencing method for rapid detection of tem-type extended-spectrum beta-lactamases in clinical strains of enterobacteriaceae. | a minisequencing method based on matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (maldi tof ms) was developed for rapid identification of single nucleotide polymorphisms at bla(tem) gene codons 104, 164 and 238 associated with extended-spectrum activity on tem-type beta-lactamases. the method was validated by testing the escherichia coli and klebsiella pneumoniae strains possessing the known bla(tem) gene sequences. | 2008 | 18694787 |
| extended spectrum beta-lactamases in enteric gram-negative bacilli: related to age and gender. | extended spectrum beta-lactamases (esbls)-producing strains of enterobacteriaceae have emerged as a major problem in hospitalized as well as community based patients. infections due to esbls-producers range from uncomplicated urinary tract infection to life threatening sepsis. the objective of this study was to find out the prevalence of esbls-producing gram- negative bacilli among clinical isolates. | 2007 | 18693612 |
| detection and reporting beta-lactam resistance phenotypes in escherichia coli and klebsiella pneumoniae: a multicenter proficiency study in spain. | the ability of 57 spanish microbiology laboratories in detecting and reporting beta-lactam resistance phenotypes in escherichia coli and klebsiella pneumoniae was evaluated. laboratories received 6 well-characterized isolates expressing the most widespread extended-spectrum beta-lactamases (esbls) in spain (4 ctx-m type, 1 tem type, and 1 shv type), 3 isolates producing ampc-type enzymes (2 plasmid mediated and 1 e. coli hyperproducing its chromosomal ampc), and 3 quality control strains. ninety ... | 2008 | 18692340 |
| investigations of the mceij-catalyzed posttranslational modification of the microcin e492 c-terminus: linkage of ribosomal and nonribosomal peptides to form "trojan horse" antibiotics. | mceij is a two protein complex responsible for attachment of a c-glycosylated and linearized derivative of enterobactin, an iron scavenger (siderophore) and product of nonribosomal peptide synthetase machinery, to the c-terminal serine residue of microcin e492 (mcce492), an 84 aa ribosomal antibiotic peptide produced by klebsiella pneumoniae ryc492. the mceij-catalyzed formation of the glycosyl ester linkage between mcce492 and the siderophore requires atp and mg(ii) as cofactors. this work addr ... | 2008 | 18690711 |
| comparison of four methods of hand washing in situations of inadequate water supply. | hand washing is the single most important means of preventing hospital acquired infections, but requires for effectiveness, a constant supply of running water and proper facilities. most developing countries do not have constant running water facilities, so alternate methods have been developed and used in clinics and hospitals. | 2008 | 18689299 |
| [antibiotic-associated diarrhea]. | most of the cases of antibiotic-associated diarrhea are benign, self-limited and presumably related to functional consequences of the alteration of gut microflora. in few cases, changes in the gut flora ecosystem allow pathogens to proliferate. clostridium difficile is responsible for approximately 10% of the cases of antibiotic-associated diarrhea in the community, most of the cases of antibiotic-associated colitis, and almost all the cases of pseudomembranous colitis. according to anatomoclini ... | 2008 | 18689117 |
| [current issues related to nosocomial infections in general surgery]. | the authors analyze the prevalence of nosocomial infections in their facility between 1999 and 2006. the annual rates ranged from 1.92 % to 4.24 %, with an average prevalence of 3.12 %. the most frequent were wound infections, febrile conditions associated with positive blood culture and urinary tract infections. in nosocomial infections, the average length of hospitalization increased by a factor of 3.5 and treatment costs rose. sporadically, multiresistant strains were detected, such as mrsa, ... | 2008 | 18688770 |
| the pathological newborn in small animals: the neonate is not a small adult. | the rate of perinatal death is variable but highest during parturition, immediately after birth and in the first days of life. infectious diseases, above all bacterial, are the second most important cause of mortality after losses during parturition. a lot of factors are involved predisposing puppies and kittens to bacterial infections: respiratory distress, hypothermia, hypoglycaemia, dehydration, congenital abnormalities. e. coli, streptococci and staphylococci, klebsiella sp., pseudomonas sp. ... | 2008 | 18688749 |
| endogenous endophthalmitis caused by hypermucoviscous klebsiella pneumoniae: an emerging disease in southeast asia and beyond. | 2008 | 18687194 | |
| in vivo and in vitro antibacterial efficacy of pds plus (polidioxanone with triclosan) suture. | this study evaluated the efficacy of polydioxanone suture with and without triclosan against gram-positive and gram-negative bacteria in vitro and in vivo. | 2008 | 18687027 |
| effectiveness and kinetics of ferrate as a disinfectant for ballast water. | this study examined whether ferrate could meet the international standards for successful ballast water treatment, including final concentrations of less than 1 cfu/ml of enterococci, less than 2.5 cfu/ml of escherichia coli, and less than 1 cfu/100 ml of vibrio cholerae. pure cultures of e. coli, klebsiella pneumoniae, and v. cholerae, and a mixed culture of enterococcus faecium and e. faecilis were grown in saline solution to simulate ballast water and were treated with dosages of ferrate rang ... | 2008 | 18686931 |
| 3-hydroxypropionaldehyde guided glycerol feeding strategy in aerobic 1,3-propanediol production by klebsiella pneumoniae. | 3-hydroxypropionaldehyde (3-hpa) is a toxic intermediary metabolite in the biological route of 1,3-propanediol biosynthesis from glycerol. 3-hpa accumulated in culture medium would arouse an irreversible cessation of the fermentation process. the role of substrate (glycerol) on 3-hpa accumulation in aerobic fermentation was investigated in this paper. 1,3-propanediol oxidoreductase and glycerol dehydratase, two key enzyme catalyzing reactions of 3-hpa formation and consumption, were sensitive to ... | 2008 | 18685876 |
| nosocomial infections in a medical-surgical intensive care unit. | we aimed to describe the pattern of nosocomial infections in an adult medical-surgical intensive care unit (icu). | 2008 | 18685276 |
| fatal infection in human flora-associated piglets caused by the opportunistic pathogen klebsiella pneumoniae from an apparently healthy human donor. | seventeen out of 24 human flora-associated (hfa) piglets died after oral administration of whole fecal flora from an apparently healthy human donor. the bacteria isolated from the organs of the infected piglets were identified as klebsiella pneumoniae by bacteriological and biochemical tests and 16s rrna gene sequence analysis. the identical k. pneumoniae strain was also isolated from the donor's fecal flora. all three neonatal piglets inoculated with k. pneumoniae from the donor's fecal flora d ... | 2008 | 18685245 |
| a phase 3, open-label, non-comparative study of tigecycline in the treatment of patients with selected serious infections due to resistant gram-negative organisms including enterobacter species, acinetobacter baumannii and klebsiella pneumoniae. | to evaluate the efficacy and safety of tigecycline in patients with selected serious infections caused by resistant gram-negative bacteria, or failures who had received prior antimicrobial therapy or were unable to tolerate other appropriate antimicrobials. secondary objectives included an evaluation of the microbiological efficacy of tigecycline and in vitro activity of tigecycline for resistant gram-negative bacteria. | 2008 | 18684704 |
| [intestinal enterobacteria of the hibernating apis mellifera mellifera l. bees]. | dynamics of enterobacteria of normal intestinal microflora was studied in apis mellifera mellifera l. bees hibernating under snow in the western urals. the cell numbers (n) of the predominant species klebsiella oxytoca increased from 10-10(6) cfu/bee in november 2004 to 10(4)-10(7) cfu/bee in march 2005; its frequency of occurrence (p) increased from 92 to 100%. increase of providencia rettgeri (11.2004: n up to 10(6), p 25%; 03.2005: n 10(2)-10(6), p 80%) was accompanied by the substitution of ... | 2008 | 18683661 |
| effects of over-expression of glycerol dehydrogenase and 1,3-propanediol oxidoreductase on bioconversion of glycerol into 1,3-propandediol by klebsiella pneumoniae under micro-aerobic conditions. | glycerol dehydrogenase (gdh) and 1,3-propanediol (1,3-pd) oxidoreductase had been proved two key enzymes for 1,3-pd production by klebsiella pneumoniae. fed-batch fermentations of the recombinant k. pneumoniae strains, over-expressing the two enzymes individually, were carried out under micro-aerobic conditions, and the behaviors of the recombinants were investigated. results showed that over-expression of 1,3-pd oxidoreductase did not affect the concentration of 1,3-pd. however, it enhanced the ... | 2009 | 18682988 |
| novel methylotrophic bacteria isolated from the river thames (london, uk). | enrichment and elective culture for methylotrophs from sediment of the river thames in central london yielded a diversity of pure cultures representing several genera of gram-negative and gram-positive bacteria, which were mainly of organisms not generally regarded as typically methylotrophic. substrates leading to successful isolations included methanol, monomethylamine, dimethylamine, trimethylamine, methanesulfonate and dimethylsulfone. several isolates were studied in detail and shown by the ... | 2008 | 18681896 |
| antibacterial activity of synthesized 2,4,5-trisubstituted imidazole derivatives. | some novel chemically synthesized 2,4,5-trisubstituted imidazoles from aryl aldehydes and 1,2-diketones or alpha-hydroxyketone were screened against eight different human pathogenic bacteria and fungi. seven compounds were found to be active against different bacteria. these compounds showed variation in activity and were found to be active against gram-positive as well as gram-negative bacteria. compound 4-(4,5-diphenyl-1h-imidazol-2-yl)-phenol, 3d was the only compound which showed activity ag ... | 2008 | 18680533 |
| spontaneous air-contrasted renography in abdominal plain film. | 2008 | 18680395 | |
| gene cloning, expression, and characterization of a novel phytase from dickeya paradisiaca. | a novel phytase gene, appa, was isolated by degenerate polymerase chain reaction (pcr) and thermal asymmetric interlaced pcr from dickeya paradisiaca. the full-length appa comprises 1278 bp and encodes 425 amino acid residues, including a 23-residue putative n-terminal signal peptide. the deduced amino acid sequence of appa reveals the conserved motifs rhgxrxp and hd, which are typical of histidine acid phosphatases; significantly, appa shows maximum identity (49%) to a phytase from klebsiella p ... | 2009 | 18679591 |
| effects of a low concentration hypochlorous acid nasal irrigation solution on bacteria, fungi, and virus. | saline irrigation would be more effective for chronic sinusitis patients if it had bactericidal effects. low concentrations of hypochlorous acid may be used as a nasal irrigation solution. first, we developed a 0.85% nacl solution by adding nacl to tap water (ph 7.0 and 8.4) and measuring the concentration of free chlorine and hypochlorous acid after giving the solution a short electrical impulse of 20 seconds. then we investigated whether the derived hypochlorous acid had a toxic effect on huma ... | 2008 | 18677274 |
| in vivo pharmacodynamics of ceftobiprole against multiple bacterial pathogens in murine thigh and lung infection models. | ceftobiprole medocaril is the parenteral prodrug of ceftobiprole, a novel pyrrolidinone broad-spectrum cephalosporin with in vitro and in vivo bactericidal activities against methicillin-resistant staphylococcus aureus (mrsa) and penicillin-resistant streptococcus pneumoniae (prsp). we have used murine thigh and lung infection models in neutropenic and normal mice to characterize the in vivo pharmacokinetic (pk)-pharmacodynamic (pd) activities of ceftobiprole against multiple strains of s. aureu ... | 2008 | 18676887 |
| tigecycline for the treatment of multidrug-resistant enterobacteriaceae: a systematic review of the evidence from microbiological and clinical studies. | antimicrobial drug resistance is spreading among enterobacteriaceae, limiting the utility of traditionally used agents. we sought to systematically review the microbiological activity and clinical effectiveness of tigecycline for multidrug-resistant (mdr) enterobacteriaceae, including those resistant to broad-spectrum beta-lactams due to the expression of extended-spectrum beta-lactamases (esbls), ampc enzymes and carbapenemases (including metallo-beta-lactamases). | 2008 | 18676620 |
| the technical aspects and clinical significance of detecting extended-spectrum beta-lactamase-producing enterobacteriaceae at a tertiary-care hospital in kuwait. | extended-spectrum beta-lactamase (esbl) production by enterobacteriaceae is an emerging problem. this 3-year prospective study was undertaken to determine the prevalence of such enzymes among the clinically significant isolates of the enterobacteriaceae family gathered from patients, and to evaluate the different techniques for their detection as well as their clinical significance. members of the enterobacteriaceae family isolated from blood, inhibited by the third-generation cephalosporins wit ... | 2008 | 18676224 |
| klebsiella oxytoca as a cause of equine abortion--short communication. | klebsiella (k.) oxytoca infection induced the abortion of a female equine fetus in the 10th month of pregnancy. bacteria were cultured from the liver, lung and stomach content. they were labelled with an anti-mycobacterium bovis antibody in the thymus, liver and lungs and were stained with giemsa and brown-brenn staining in the thymus and lung. the diffusely consolidated lungs contained numerous grey-whitish foci 2-4 mm in diameter, which corresponded to severe pyogranulomatous pneumonia charact ... | 2008 | 18669249 |
| antimicrobial activity of essential oil and major constituents of salvia chloroleuca. | the aerial parts of salvia chloroleuca were collected at full flowering stage at shahrestanak (tehran province of iran). the essential oil was isolated by hydrodistillation and analyzed by combination of capillary gc and gc-ms. thirty-four components were identified, representing 98.5% of the total oil. beta-pinene (10.6%), alpha-pinene (9.0%), beta-caryophyllene (9.0%), 1,8-cineole (9.0%) and carvacrol (7.9%) were the main components. the in vitro antimicrobial activity of the essential oil of ... | 2008 | 18669017 |
| infections in gastroschisis: organisms and factors. | this study aimed to define the incidence, causative organisms and predisposing factors leading to infection related morbidity in newborns with gastroschisis. all gastroschisis patients admitted over the 5-year period (1999-2004) were retrospectively reviewed. surveillance samples, wound, blood, urine and fecal cultures were analyzed. duration of total parenteral nutrition, antibiotic therapy, feeding regimes and demographic data were also analyzed. multiple logistic regression was employed using ... | 2008 | 18668249 |
| expansion and countrywide dissemination of st11, st15 and st147 ciprofloxacin-resistant ctx-m-15-type beta-lactamase-producing klebsiella pneumoniae epidemic clones in hungary in 2005--the new 'mrsas'? | to investigate the molecular epidemiology of ciprofloxacin-resistant ctx-m-15-producing klebsiella pneumoniae epidemic clones (ecs) isolated from six nosocomial outbreaks and sporadic cases during 2005 in hungary. | 2008 | 18667450 |
| chemical composition and antimicrobial activities of the essential oil from the seeds of enterolobium contortisiliquum (leguminosae). | seeds of enterolobium contortisiliquum were subjected to steam distillation to obtain a light yellow essential oil in a yield of 3 ml/kg of seeds. the major components of the oil were identified using gas chromatography/mass spectrometry (gc-ms) and were furfural, limonene, linalool, estragole, carvone, and apiole with carvone representing more than 50% of the total composition. antimicrobial activities of the essential oil were determined against four species of gram positive bacteria (bacillus ... | 2008 | 18665989 |
| a comparison of computed tomography, magnetic resonance imaging, and digital subtraction angiography findings in the diagnosis of infected aortic aneurysm. | to characterize imaging findings from computed tomography, magnetic resonance imaging, and angiogram in patients with infected aortic aneurysm. | 2008 | 18664851 |
| risk factor analysis of invasive liver abscess caused by the k1 serotype klebsiella pneumoniae. | the increasing prevalence of klebsiella pneumoniae liver abscess in asian countries is attributable to virulent strains of the k1 serotype. we investigated the risk factors for the k1 serotype k. pneumoniae liver abscess. a case-control study was performed using the database of a nationwide study of liver abscess in korea. multivariate logistic regression analysis was performed for 78 cases of the k1 serotype k. pneumoniae liver abscess and 81 controls with non-klebsiella. diabetes mellitus was ... | 2009 | 18663497 |
| surveillance of community-based reservoirs reveals the presence of ctx-m, imported ampc, and oxa-30 beta-lactamases in urine isolates of klebsiella pneumoniae and escherichia coli in a u.s. community. | beta-lactamases produced by urine isolates from patients in long-term care facilities (ltcfs), outpatient, clinics, and one hospital in a u.s. community were characterized. a total of 1.3% of all escherichia coli and klebsiella pneumoniae isolates collected from patients in 30 ltcfs and various outpatient clinics produced extended-spectrum beta-lactamases (esbls) and/or imported ampc beta-lactamases. | 2008 | 18663030 |
| molecular and biochemical characterization of shv-56, a novel inhibitor-resistant beta-lactamase from klebsiella pneumoniae. | a clinical strain of klebsiella pneumoniae was found to possess the chromosomal gene bla(shv-56), encoding a new inhibitor-resistant beta-lactamase with a pi of 7.6. shv-56 is derived from shv-11 by the single substitution k234r. this mutation therefore evidences a new critical site for inhibitor resistance among shv enzymes. | 2008 | 18663019 |
| anti-inflammatory effect of thalidomide alone or in combination with augmentin in klebsiella pneumoniae b5055 induced acute lung infection in balb/c mice. | thalidomide (alpha-naphtylimidoglutarimide), a psychoactive drug that readily crosses blood-brain barrier, has been shown to exhibit anti-inflammatory, anti-angiogenic, immunomodulatory properties through a mechanism that is not fully established. keeping these properties in mind, we tried to find out the anti-inflammatory properties of thalidomide in mouse model of acute inflammation by introducing k. pneumoniae b5055 in balb/c mice via intranasal route. the intranasal instillation of bacteria ... | 2008 | 18662682 |
| bacteremia in children at the university hospital in riyadh, saudi arabia. | bacteremia is a major pediatric health care problem despite the availability of new modalities in the management of this disease. the aim of the present study was to determine the incidence and pattern of bacteremia in pediatric group at a tertiary hospital in riyadh, saudiarabia. | 2008 | 18661767 |
| comment on: control of extended-spectrum beta-lactamase-producing klebsiella pneumoniae using a computer-assisted management program to restrict third-generation cephalosporin use. | 2008 | 18658195 | |
| bronchoperitoneal fistula from a lung abscess. | fistula formation between the bronchi and peritoneal cavity is extremely rare. in previous reports, fistulas have occurred secondary to thoraco-abdominal trauma, subphrenic abscess, suppurative biliary tract obstruction, malignancy and iatrogenically through procedures such as biliary surgery or percutaneous biliary drainage. the direction of fistula formation has always been thought to be from the peritoneal cavity to the bronchi: there are no reports of a fistula with a bronchial origin. this ... | 2008 | 18657063 |
| bioactive brominated metabolites from the red sea sponge suberea mollis. | reinvestigation of the red sea sponge suberea mollis afforded two new bromotyrosine-derived alkaloids, subereamollines a (1) and b (2), two new brominated phenolic compounds, subereaphenols b (7) and c (9), and the known compounds aerothionin (3), homoaerothionin (4), 11,19-dideoxyfistularin-3 (5), aeroplysinin-1 (6), and aeroplysinin-2 (8). the structure determination of the isolated compounds was assigned using one- and two-dimensional nmr spectra and hrfabms data. the antimicrobial and antiox ... | 2008 | 18656986 |
| antibiotics in the intensive care unit: focus on agents for resistant pathogens. | antibiotic resistance is increasing faster than the drug industry can develop and market new antibiotics. medical personnel commonly must deal with the resistant gram-positive pathogens including mrsa and vre, in addition to the problem gram-negative bacteria, pseudomonas, acinetobacter, and esbl producing strains of klebsiella and e. coli. clinicians should be familiar with treatment strategies for these resistant pathogens. because of the lack of novel agents to treat resistant infections, cli ... | 2008 | 18655946 |
| complete genome sequence of the n2-fixing broad host range endophyte klebsiella pneumoniae 342 and virulence predictions verified in mice. | we report here the sequencing and analysis of the genome of the nitrogen-fixing endophyte, klebsiella pneumoniae 342. although k. pneumoniae 342 is a member of the enteric bacteria, it serves as a model for studies of endophytic, plant-bacterial associations due to its efficient colonization of plant tissues (including maize and wheat, two of the most important crops in the world), while maintaining a mutualistic relationship that encompasses supplying organic nitrogen to the host plant. genomic ... | 2008 | 18654632 |
| necrotizing fasciitis in patients with liver cirrhosis: predominance of monomicrobial gram-negative bacillary infections. | necrotizing fasciitis (nf), a rare but severe infection, usually occurs in individuals with underlying chronic illness, but its clinical presentation among cirrhotic patients is infrequently discussed. forty-two cirrhotic patients with 47 episodes of nf between 1995 and 2006 were analyzed. their mean age was 55.6 years, with male preponderance (34 patients, 81%). lower extremities were mainly involved (70%). of 42 episodes with identified pathogens, 41 (97%) were monomicrobial infections and wer ... | 2008 | 18653302 |
| identification of enterobacteriaceae on vacuum loaders in shell egg processing. | cleaning and sanitation are paramount in food processing. gaining an understanding of the microbial populations present in a processing facility can help in the development of effective and efficient cleaning. the current study was undertaken to gain a better understanding of the enterobacteriaceae present on vacuum loader cups used in shell egg processing to transfer nest run eggs to the processing line. twenty cups were rinsed on each of 3 visits to both an off-line operation and a mixed opera ... | 2008 | 18648066 |
| cefuroxime non-susceptibility in multidrug-resistant klebsiella pneumoniae overexpressing rama and acra and expressing ompk35 at reduced levels. | the aims were to study if efflux and down-regulation of porins contribute to cefuroxime resistance in klebsiella pneumoniae and to co-resistance to unrelated antibiotics. | 2008 | 18647746 |
| plasma-enhanced synthesis of bactericidal quaternary ammonium thin layers on stainless steel and cellulose surfaces. | we have investigated bottom-up chemical synthesis of quaternary ammonium (qa) groups exhibiting antibacterial properties on stainless steel (ss) and filter paper surfaces via nonequilibrium, low-pressure plasma-enhanced functionalization. ethylenediamine (ed) plasma under suitable conditions generated films rich in secondary and tertiary amines. these functional structures were covalently attached to the ss surface by treating ss with o 2 and hexamethyldisiloxane plasma prior to ed plasma treatm ... | 2008 | 18646726 |
| bacterial flora of captive houbara (chlamydotis undulata), kori (ardeotis kori) and rufous-crested (eupodotis ruficrista) bustards. | a survey was carried out to investigate the aerobic bacterial flora of captive houbara (chlamydotis undulata), kori (ardeotis kori) and rufous-crested (eupodotis ruficrista) bustards maintained at the national avian research center, abu dhabi, united arab emirates. none of the houbara or rufous-crested bustards sampled were bred in captivity by the center but four of the kori bustards sampled were captive-bred. faecal, cloacal, oropharyngeal and skin samples (from under the wing) from clinically ... | 1996 | 18645872 |
| plasmid-encoded carbapenem-hydrolyzing beta-lactamase oxa-48 in an imipenem-susceptible klebsiella pneumoniae strain from belgium. | 2008 | 18644970 | |
| streptozocin-induced diabetic mouse model of urinary tract infection. | diabetics have a higher incidence of urinary tract infection (uti), are infected with a broader range of uropathogens, and more commonly develop serious uti sequelae than nondiabetics. to better study uti in the diabetic host, we created and characterized a murine model of diabetic uti using the pancreatic islet beta-cell toxin streptozocin in c3h/hen, c3h/hej, and c57bl/6 mouse backgrounds. intraperitoneal injections of streptozocin were used to initiate diabetes in healthy mouse backgrounds, a ... | 2008 | 18644886 |
| a tripartite efflux pump involved in gastrointestinal colonization by klebsiella pneumoniae confers a tolerance response to inorganic acid. | the colonization of the gastrointestinal tract of patients by the opportunistic gram-negative bacillus klebsiella pneumoniae generally occurs prior to the development of nosocomial infections. mutant strain c-81 was isolated owing to its reduced capacity to colonize the digestive tract in a murine model following transposon mutagenesis (n. maroncle, d. balestrino, c. rich, and c. forestier, infect. immun. 70:4729-4734, 2002). nucleotide sequence analysis showed that the transposon had inserted i ... | 2008 | 18644883 |
| mitracarpus frigidus aerial parts exhibited potent antimicrobial, antileishmanial, and antioxidant effects. | the crude extract and the hexane, ch(2)cl(2), etoac, n-buoh, and hydromethanolic fractions of the aerial parts of mitracarpus frigidus were evaluated against promastigote forms of two species of leishmania (l. chagasi and l. amazonensis), 11 strains of bacteria (staphylococcus aureus, pseudomonas aeruginosa, salmonella enterica sorovar tythimurium, shigella sonnei, klebsiella pneumoniae, escherichia coli, micrococcus luteus, enterococcus faecalis, enterobacter cloacae, streptococcus pyogenes and ... | 2009 | 18644325 |
| anti-biofilm properties of chitosan-coated surfaces. | surfaces coated with the naturally-occurring polysaccharide chitosan (partially deacetylated poly n-acetyl glucosamine) resisted biofilm formation by bacteria and yeast. reductions in biofilm viable cell numbers ranging from 95% to 99.9997% were demonstrated for staphylococcus epidermidis, staphylococcus aureus, klebsiella pneumoniae, pseudomonas aeruginosa and candida albicans on chitosan-coated surfaces over a 54-h experiment in comparison to controls. for instance, chitosan-coated surfaces re ... | 2008 | 18644229 |
| predictors of septic metastatic infection and mortality among patients with klebsiella pneumoniae liver abscess. | primary liver abscess caused by klebsiella pneumoniae is an infection that is emerging worldwide and that is associated with severe morbidity and considerable mortality. | 2008 | 18643760 |
| community-acquired klebsiella pneumoniae complicated skin and soft-tissue infections of extremities: emphasis on cirrhotic patients and gas formation. | klebsiella pneumoniae was rarely reported to cause complicated skin and soft tissue infections (csstis). our study was to delineate clinical characteristics and outcome of csstis involving extremities caused by k. pneumoniae. | 2008 | 18642112 |
| antimicrobial activity of south african podocarpus species. | several species of podocarpus (podocarpaceae) are utilized in treating ailments across the world. in africa, four species are used traditionally in both animal and human health. | 2008 | 18639622 |
| proanthocyanidins: target compounds as antibacterial agents. | grape seeds accumulate in huge quantities as byproduct during wine production and are therefore a cheap source for pharmacologically active agents. however, studies prove poor antibacterial activity, and results of analyses are sometimes contradictory. the aim of this study was, thus, to determine the antibacterial activity of grape seed extracts with special focus on the chromatographic characterization of active fractions. in the course of these investigations, extraction protocols were optimi ... | 2008 | 18636738 |
| production of recombinant bacterial endoglucanase as a co-product with ethanol during fermentation using derivatives of escherichia coli ko11. | this study demonstrates a new approach to reduce the amount of fungal cellulase required for the conversion of cellulose into ethanol. escherichia coli ko11, a biocatalyst developed for the fermentation of hemicellulose syrups, was used to produce recombinant endoglucanase as a co-product with ethanol. seven different bacterial genes were expressed from plasmids in ko11. all produced cell-associated endoglucanase activity. ko11(ploi1620) containing erwinia chrysanthemi celz (egz) produced the hi ... | 1997 | 18636522 |
| kinetic resolution of alpha-methylbenzylamine with omicron-transaminase screened from soil microorganisms: application of a biphasic system to overcome product inhibition. | two microorganisms showing high omicron-transaminase activity (klebsiella pneumoniae js2f and bacillus thuringiensis js64) were screened by the enrichment method using (s)-alpha-methylbenzylamine (alpha-mba) as a sole nitrogen source. optimal carbon and nitrogen sources for enzyme induction and the properties of omicron-transaminases were investigated. omicron-transaminase from b. thuringiensis js64 was highly enantioselective (e = 75.3) for (s)-enantiomer of alpha-mba and showed remarkable stab ... | 1997 | 18636493 |
| clinical impact and risk factors for percutaneous gastrostomy wound infections due to resistant organisms. | 2008 | 18635384 | |
| [hydrophobic and hemagglutinating properties of klebsiella pneumoniae and klebsiella oxytoca]. | the aim of this study was to estimated hydrophobic and hemnagglutinating properties of klebsiella pneumoniae and klebsiella oxytoca rods. the hydrophobcity was evaluated according to the method of rosenberg et al. the hemagglutinating properties were estimated by method of blanco et al. forty seven hydrophobic klebsiella strains (30 k. pneumoniae strains and 17 k. oxytoca strains) were detected. hemagglutinating properties were observed in 65 klebsiella strains (45 k. pneumoniae strains and 20 k ... | 2008 | 18634343 |
| [esbl-positive and esbl-negative klebsiella pneumoniae and klebsiella oxytoca strains--occurrence in clinical specimens and susceptibility to selected antibiotics]. | the aim of this study was to evaluated susceptibility to selected antibiotics and occurrence in clinical materials esbl-positive and esbl-negative k. pneumoniae and k. oxytoca strains. the susceptibility to selected antibiotics were tested by disk-diffusion method. none of the analysed strains was resistant to imipenem. among non beta-lactam antibiotics thwe most strains were susceptible to fluoroquinolones. the most frequently k. pneumoniae strains were isolated from urine, k. oxytoca trains we ... | 2008 | 18634342 |
| reagent switchable stereoselective beta(1,2) mannoside mannosylation: oh-2 of mannose is a privileged acceptor. | the discovery of novel conditions for highly beta-stereoselective (>9 : 1) mannosylation of oh-2 of mannosides using a straightforward perbenzylthioglycoside donor has allowed ready assembly of beta-mannosyl oligosaccharides including the repeating trisaccharide motif of the o5 antigen of pathogen klebsiella pneumoniae. | 2008 | 18633526 |
| evaluation of chromagar kpc for rapid detection of carbapenem-resistant enterobacteriaceae. | a new chromagar kpc medium was compared to macconkey agar with carbapenem discs and pcr for the bla(kpc) gene for rapid detection of carbapenem-resistant klebsiella pneumoniae. the sensitivity and specificity relative to pcr were 100% and 98.4%, respectively, for chromagar kpc and 92.7% and 95.9%, respectively, for macconkey agar. | 2008 | 18632915 |
| trends in bacterial pathogens of lower respiratory tract infections. | this study was conducted to determine the bacterial aetiology of lower respiratory tract infections in this environment as well as update the clinicians in the various antimicrobial alternatives available in the treatment. | 2008 | 18630792 |
| kinetic, dynamic, and pathway studies of glycerol metabolism by klebsiella pneumoniae in anaerobic continuous culture: ii. analysis of metabolic rates and pathways under oscillation and steady-state conditions. | the oscillation phenomena reported in the preceding article for the anaerobic continuous fermentation of glycerol by klebsiella pneumoniae are analyzed in terms of metabolic fluxes (metabolic rates and yields) and stoichiometry of pathways. significant oscillations in the fluxes of co(2), h(2), formic acid, ethanol, and reducing equivalents are observed which show obvious relationships to each other. changes in the consumption or production rates of glycerol, acetic acid, 1,3-propanediol, and at ... | 1996 | 18629929 |
| kinetic, dynamic, and pathway studies of glycerol metabolism by klebsiella pneumoniae in anaerobic continuous culture: i. the phenomena and characterization of oscillation and hysteresis. | oscillation and hysteresis phenomena are observed in the anaerobic continuous fermentation of glycerol by klebsiella pneumoniae in long-term cultivations under a variety of conditions. in this work, the conditions for the occurrence of these phenomena are reported and the patterns of cell growth and metabolism under oscillation are characterized. during an oscillation period, the formation rates of co(2), h(2), and formate and the consumption rate of alkali periodically pass values of maxima and ... | 1996 | 18629928 |
| need for more environmental control of klebsiella and other gram negative infections. | 2008 | 18626550 | |
| real-time pcr and statistical analyses of acrab and rama expression in clinical isolates of klebsiella pneumoniae. | clinical isolates of klebsiella pneumoniae were tested for a correlation between tigecycline mic and expression of rama by using real-time pcr. at mics of 4 and 8 microg/ml, the expression of rama was statistically significantly different from mics of 2 microg/ml or less, supporting the tigecycline susceptibility breakpoint of <or=2 microg/ml for k. pneumoniae. | 2008 | 18625776 |
| klebsiella oxytoca: opportunistic infections in laboratory rodents. | opportunistic pathogens have become increasingly relevant as the causative agents of clinical disease and pathological lesions in laboratory animals. this study was conducted to evaluate the role of klebsiella oxytoca as an opportunistic pathogen in laboratory rodents. therefore, k. oxytoca-induced lesions were studied from 2004 to early 2006 in naturally infected rodent colonies maintained at the jackson laboratory (tjl), bar harbor, usa, the animal research centre (tierforschungszentrum, tfz) ... | 2008 | 18625592 |
| predictors of mortality from community-onset bloodstream infections due to extended-spectrum beta-lactamase-producing escherichia coli and klebsiella pneumoniae. | in a cohort study of 36 patients with community-onset extended-spectrum beta-lactamase (esbl)-producing escherichia coli or klebsiella pneumoniae bloodstream infections, we found that predictors of mortality were community-onset infection with esbl-producing k. pneumoniae pathogens (p = .02) and failure to receive an initial empirical regimen that included either beta-lactam and beta-lactamase-inhibitors or a carbapenem (p = .04). | 2008 | 18624669 |
| differential correlation between rates of antimicrobial drug consumption and prevalence of antimicrobial resistance in a tertiary care hospital in greece. | to investigate whether there is a correlation between the rates of antimicrobial drug consumption in hospital departments and the prevalence of antimicrobial resistance among clinically important bacteria recovered in the hospital. | 2008 | 18624668 |
| biofilm parameters influencing biocide efficacy. | the influence of biofilm areal cell density, species composition, and the presence of abiotic particles on the disinfection and removal of bacterial biofilms by monochloramine was investigated. mono- and binary population biofilms of pseudomonas aeruginosa and klebsiella pneumoniae were grown on stainless-steel slides in a continuous flow annular reactor. biofilms were treated in the reactor with a pulse/step dose of 4 mg/l monochloramine for 2 h. biofilm samples were disaggregated and assayed f ... | 1995 | 18623350 |
| quantitative analysis of biofilm thickness variability. | the thickness variability of biofilms of pseudomonas aeruginosa, klebsiella pneumoniae, and the binary population combination of these two species was quantified. the experimental method involved cryoembedding biofilms with a commercial tissue embedding agent, sectioning, and applying image analysis to construct thickness profiles along linear transects (up to 1 cm in length) across the substratum. biofilms embedded and sectioned by this method were locally as thin as a single cell attached to t ... | 1995 | 18623250 |
| microbial production of (+)-trans-isochorismic acid. | two methods are described for the preparation of enantiomerically pure (+)-trans-isochorismic acid, an important metabolite of the postchorismate pathway. both methods can be employed to prepare isotopically labeled isochorismic acid. one of the two methods is suitable to prepare bulk quantities of isochorismic acid using a recombinant strain of klebsiella pneumoniae 62-1. (c) 1995 john wiley & sons, inc. | 1995 | 18623181 |
| infections following damage control laparotomy with abdominal packing. | our objective was to describe postoperative infections for patients undergoing damage control laparotomy (dcl) with abdominal packing. we retrospectively reviewed data on packing patients in jinling hospital (china) during a 5-y period. of 26 patients, 15 (57.7%) had postoperative infections. pneumonia/lower respiratory tract infection (57.7%), bacteraemia (50%), and urinary tract infection (15.4%) were the 3 prominent types of infections. the most frequently isolated bacteria were pseudomonas a ... | 2008 | 18622805 |
| penetration into and exposure of cefozopran in pelvic retroperitoneal space exudate. | this study aimed to examine the penetration into and exposure of cefozopran in the pelvic retroperitoneal space exudate of patients undergoing radical hysterectomy and pelvic lymphadenectomy. cefozopran (1 g) was administered by 1-h infusion after the end of surgery, and venous blood and exudate samples were obtained 0.5, 1, 1.5, 2, 3, 4, 5, 6, and 8 h thereafter. drug concentrations in serum and the exudate were determined by a bioassay, analyzed pharmacokinetically, and used for a monte carlo ... | 2008 | 18622684 |
| pharmacokinetic-pharmacodynamic target attainment analysis of cefozopran in japanese adult patients. | this study aimed to perform a pharmacokinetic-pharmacodynamic (pk-pd) target attainment analysis to create a dosing strategy for cefozopran in japanese adult patients. a total of 145 plasma concentration samples from 32 adult patients were used for a population pharmacokinetic modeling and monte carlo simulation to assess the probability of attaining the pk-pd target (70% of the time above the minimum inhibitory concentration for the bacterium). the final population pharmacokinetic model was bas ... | 2008 | 18622676 |
| peritoneal pharmacokinetics of cefepime in laparotomy patients with inflammatory bowel disease, and dosage considerations for surgical intra-abdominal infections based on pharmacodynamic assessment. | this study aimed to examine the peritoneal pharmacokinetics of cefepime and to assess its pharmacodynamic exposure in peritoneal fluid (pf). cefepime (1 g) was administered to eight patients with inflammatory bowel disease before abdominal surgery. venous blood and pf samples were obtained at the end of the 0.5-h infusion and at 1, 2, 3, 4, 5, and 6 h thereafter. drug concentrations in plasma and pf were determined, analyzed pharmacokinetically, and used for a monte carlo simulation with minimum ... | 2008 | 18622673 |
| genetic characterisation of ctx-m-15-producing klebsiella pneumoniae and escherichia coli strains isolated from stem cell transplant patients in tunisia. | characterisation of extended-spectrum beta-lactamase (esbl) genes and their genetic environments as well as the presence of integrons were analysed in nine klebsiella pneumoniae and two escherichia coli esbl-positive isolates recovered in the centre of bone marrow transplantation of tunisia. all strains harboured the bla(ctx-m-15) gene and presented minimum inhibitory concentrations for cefotaxime and ceftazidime of 256-1024 mg l(-1) and 16-512 mg l(-1), respectively, and eight of them showed di ... | 2008 | 18620848 |
| survey of childhood empyema in asia: implications for detecting the unmeasured burden of culture-negative bacterial disease. | parapneumonic empyema continues to be a disease of significant morbidity and mortality among children despite recent advances in medical management. to date, only a limited number of studies have assessed the burden of empyema in asia. | 2008 | 18620553 |
| multiple product inhibition and growth modeling of clostridium butyricum and klebsiella pneumoniae in glycerol fermentation. | the inhibition potentials of products and substrate on the growth ofclostridium butyricum and klebsiella pneumoniae in the glycerol fermentation are examined from experimental data and with a mathematicalmodel. whereas the inhibition potential of externally added and self-produced 1,3-propanediol is essentially the same, butyric acid produced by the culture is more toxic than that externally added. the same seems to apply for acetic acid. the inhibitory effect of butyric acid is due tothe total ... | 1994 | 18618908 |
| saccharification and fermentation of sugar cane bagasse by klebsiella oxytoca p2 containing chromosomally integrated genes encoding the zymomonas mobilis ethanol pathway. | pretreatment of sugar cane bagasse is essential for a simultaneous saccharification and fermentation (ssf) process which uses recombinant klebsiella oxytoca strain p2 and genencor spezyme ce. strain p2 has been genetically engineered to express zymomonas mobilis genes encoding the ethanol pathway and retains the native ability to transport and metabolize cellobiose (minimizing the need for extracellular cellobiase). in ssf studies with this organism, both the rate of ethanol production and ethan ... | 1994 | 18618690 |
| synthesis and in-vitro antibacterial activity of 5-substituted 1-methyl-4-nitro-1h-imidazoles. | a series of 5-substituted 1-methyl-4-nitro-1h-imidazole derivatives were synthesized and evaluated for in-vitro antibacterial activity against a panel of microorganisms including staphylococcus aureus, staphylococcus epidermidis, bacillus subtilis, escherichia coli, klebsiella pneumonia, enterobacter aerogenes, and helicobacter pylori using conventional agar dilution method. among the test compounds, 1-methyl-4-nitro-5-(phenylsulfonyl)-1h-imidazole was the most potent against gram-positive bacte ... | 2008 | 18618489 |
| design, synthesis and antibacterial activity of novel actinonin derivatives containing benzimidazole heterocycles. | a series of novel actinonin derivatives containing a benzimidazole heterocycle linked as amide isostere have been designed and synthesized. the structures of all the synthesized compounds were confirmed by analytical and spectroscopic methods. all the compounds were evaluated in vitro against staphylococcus aureus, klebsiella pneumoniae, and sarcina lutea. among them, compound 1a with unsubstituted benzimidazole ring exhibited potent antibacterial activities. | 2009 | 18617291 |
| in vitro multimerization and membrane insertion of bacterial outer membrane secretin puld. | synthesis of the klebsiella oxytoca outer membrane secretin puld, or its membrane-associated core domain, in a liposome-supplemented escherichia coli in vitro transcription-translation system resulted in the formation of multimers that appeared as typical dodecameric secretin rings when examined by negative-stain electron microscopy. cryo-electron microscopy of unstained liposomes and differential extraction by urea indicated that the secretin particles were inserted into the liposome membranes. ... | 2008 | 18616949 |
| rapid detection of blakpc carbapenemase genes by real-time pcr. | carbapenem resistance among enterobacteriaceae is an emerging problem worldwide. klebsiella pneumoniae carbapenemase (bla(kpc)) enzymes are among the most common beta-lactamases described. in this study, we report the development and validation of a real-time pcr (q-pcr) assay for the detection of bla(kpc) genes using taqman chemistry. the q-pcr amplification of bla(kpc) dna was linear over 7 log dilutions (r(2) = 0.999; slope, 3.54), and the amplification efficiency was 91.6%. the q-pcr detecti ... | 2008 | 18614657 |
| proteolytic activity in stored aerobic granular sludge and structural integrity. | aerobic granules lose stability during storage. the goal of this work was to highlight the main cause of stability loss for stored granules as intracellular protein hydrolysis. the quantity of extracellular proteins was noted to be significantly lower during granule storage, and protease enzyme activities were correspondingly higher in the cores of stored granules. the proteolytic bacteria, which secrete highly active protease enzymes, were for the first time isolated and characterized by analyz ... | 2009 | 18614356 |
| [tracheopathia osteoplastica]. | report a case of tracheopathia osteoplastica and describe from a literature analysis the main clinical, radiological, and therapeutic features of this rare disease based on literature review. | 2008 | 18614154 |
| an energetic model for oxygen-limited metabolism. | microbial production of 2,3-butanediol by klebsiella oxytoca occurs under conditions of an oxygen limitation. the extent to which substrate is oxidized to 2,3-butanediol and its coproducts, (acetic acid, acetoin, and ethanol) and the relative flow rates of substrate to energetic and biosynthetic pathways are controlled by the degree of oxygen limitation. two energetic relationships which describe the response to an oxygen limitation have been derived. the first relationship describes the couplin ... | 1993 | 18612954 |
| optimization of 2,3-butanediol production by klebsiella oxytoca through oxygen transfer rate control. | production of 2,3-butanediol by klebsiella oxytoca is influenced by the degree of oxygen limitation. during batch culture studies, two phases of growth are observed: energy-coupled growth, during which cell growth and oxygen supply are coupled; and, energy-uncoupled growth, which arises when the degree of oxygen limitation reaches a critical value. optimal 2,3-butanediol productivity occurs during the energy-coupled growth phase. in this article, a control system which maintains the batch cultur ... | 1993 | 18612953 |
| antimicrobial activity and durability of a novel antimicrobial-impregnated bladder catheter. | the main objective of this study was to examine the antimicrobial activity and durability of a novel indwelling bladder catheter impregnated with minocycline and rifampin. thirty antimicrobial-impregnated bladder catheters were inserted transurethrally in spinal cord-injured patients and removed, in six groups of five catheters each, at 3, 7, 10, 14, 17 or 21 days. removed catheters had detectable zones of inhibition against two different clinical isolates of each of the 10 tested uropathogens ( ... | 1997 | 18611809 |
| observations on oral sultamicillin/unasyn cp-45 899 therapy of neonatal infections. | the use of an effective antimicrobial remains a problem in the neonate, thereby necessitating empiric combinations of parenteral agents. we therefore studied oral sultamicillin's (unasyn cp-45 899) efficacy and tolerability (dose = 50 mg/kg per day) in the treatment of serious infections in 27 neonates over an 18 month period. the study cohort comprised newborns with suspected or confirmed infections in the special care baby unit of a referral hospital. the infants with overwhelming/severe infec ... | 1997 | 18611789 |
| klebsiella and extended spectrum beta-lactamases. | during the past 14 years a rapid, world-wide increase in prevalence of klebsiella pneumoniae resistant to late generation cephalosporins has occurred. a growing number of newly identified plasmid encoded beta-lactam hydrolyzing enzymes has broadened the spectrum of primitive beta-lactamases allowing inactivation of a wide variety of beta-lactam agents. the extrachromosomal genes which code for these enzymes often exist with genes expressing resistance to several other classes of antibacterial ag ... | 1997 | 18611783 |
| susceptibility of pseudomonas aeruginosa to a photodynamic effect of the arginine hematoporphyrin derivative. | the photodynamic effect of the arginine hematoporphyrin derivative (hpd-arg(2)) on the growth of selected pseudomonas aeruginosa clinical isolates is described as compared to the effect of hematoporphyrin derivative (hpd). growth inhibition of hpd-arg(2) of three gram-positive strains (staphylococcus aureus, bacillus subtilis and micrococcus luteus) and five laboratory strains of gram-negative bacteria (escherichia coli, proteus vulgaris, p. aeruginosa, klebsiella pneumoniae and enterobacter clo ... | 1997 | 18611781 |
| comparative in vitro studies on the beta-lactamase-inhibiting effect of clavulanic acid and sulbactam on ampicillin-resistant enterobacteriaceae. | clavulanic acid and sulbactam alone are ineffective against pseudomonas and enterococci. staphylococci and enterobacteriaceae are inhibited by high concentrations not attainable under clinical conditions. strains of acinetobacter, especially a. lwoffii are susceptible to clavulanic acid and highly susceptible to sulbactam. the ampicillin/sulbactam combination is superior to ampicillin/clavulanic acid against citrobacter freundii, enterobacter spp. and morganella morganii. the latter combination ... | 1996 | 18611726 |
| comparison of sulbactam/ampicillin and cefuroxime in infections of the lower respiratory tract: results of a prospective, randomized and comparative study. | in a randomized, prospective study, ampicillin (amp) in combination with the beta-lactamase-inhibitor sulbactam (sbt) was compared with cefuroxime (cxm) in 73 hospitalized patients with lower respiratory tract infections. of these patients 36 received sbt/amp 1 g/2 g tid and 37 received cxm 1.5 g tid - both in the form of intravenous infusion. the duration of treatment ranged from 5 to 12 days, with a median of 8 days in each group. in the sbt/amp group, 23 patients (64%) had pneumonia, while 13 ... | 1996 | 18611723 |