Publications

fibrinogen nagoya, a replacement of glutamine-329 by arginine in the gamma-chain that impairs the polymerization of fibrin monomer.	structural studies on a hereditary abnormal fibrinogen, fibrinogen nagoya (takamatsu, j., ogata, k., kamiya, t., koie, k., takagi, t., & iwanaga, s. (1979) thromb. haemost. 42, 78), were performed to identify the abnormality responsible for the impaired polymerization of fibrin monomer. upon sodium dodecyl sulfate-polyacrylamide gel electrophoresis under reducing conditions, fibrinogen nagoya showed the presence of an extra protein band with an apparent molecular weight of 49,500 in addition to ...	2009	2738036
panic attack-associated placental abruption: a case report.	a case of placental abruption is described in a nonmedicated pregnant woman with panic disorder who experienced panic symptoms and resultant hypertension. the authors suggest that sympathetic arousal associated with panic symptoms may have an adverse effect on the fetoplacental unit. the potential impact of untreated anxiety symptoms on fetal well-being must be considered when deciding whether pharmacotherapeutic intervention is appropriate for certain patients with anxiety disorders.	2009	2738032
relationship between multiple drug-resistance & enterotoxin production by shigella species.	culture filtrates prepared with strains of shigella dysenteriae 1 and those of sh. flexneri and sh. sonnei, collected from different geographical locations in india caused accumulation of fluid in rabbit gut loops, indicating their capability to produce shiga and shiga-like toxins respectively. sh. boydii strains were noted for the first time to produce shiga-like toxins. the failure of production of fluid accumulation in rabbit gut by shigella strains that lacked the r-markers of the antibiotic ...	1989	2737704
[a three years follow-up study on the blood pressures of 6111 children in chengdu].	this paper reports the results of a follow-up study in blood pressures of 6111 children for 3 years in chengdu city and the villages around. it was showed that the blood pressure for both the city and village children were elevated in overall with age. among the city children, the rate of bp-rising varied in different periods of childhood and that of girls above 13 was not significant. among village children, the rate of bp-rising for both male and female comparison to that of urban ones were si ...	2009	2736619
late brain abscess years after severe cerebrocranial trauma with fronto-orbitobasal fracture.	an 8-year-old boy suffered severe craniocerebral trauma with left-sided fronto-orbitobasal fracture. the ct scan showed minor subdural air inclusions. the child recovered well and had no clinical signs of aftereffects. eight years after the accident, symptoms of intracranial pressure developed progressively with nuchal rigidity and elevated temperature. the ct showed an extensive left fronto-orbitobasal abscess. the intraoperative finding was a brain prolapse both into the frontal sinus and into ...	2008	2736550
late brain abscess years after severe cerebrocranial trauma with fronto-orbitobasal fracture.	an 8-year-old boy suffered severe craniocerebral trauma with left-sided fronto-orbitobasal fracture. the ct scan showed minor subdural air inclusions. the child recovered well and had no clinical signs of aftereffects. eight years after the accident, symptoms of intracranial pressure developed progressively with nuchal rigidity and elevated temperature. the ct showed an extensive left fronto-orbitobasal abscess. the intraoperative finding was a brain prolapse both into the frontal sinus and into ...	2008	2736550
[papillary cystadenocarcinoma of the kidney. apropos of a case and review of the literature].		2002	2732502
hemiplegia and amputation: rehabilitation in the dual disability.	about 10% of all elderly dysvascular amputees have had cerebrovascular accidents at some time. this is an often overlooked but important fact which significantly impacts the outcomes of their rehabilitation, especially where prosthetic ambulation is attempted. this study reviews the rehabilitation outcomes of 46 patients with the dual disability of hemiplegia and amputation. the mean age of the patients was 63 years (range 49 to 84). forty-one (89%) could participate in a trial of physical thera ...	2002	2730308
large phosphate shifts with treatment for hyperglycemia.	although hypophosphatemia is known to commonly accompany therapy for hyperglycemia, it is not generally appreciated that severe life-threatening depletion of phosphate may occur. i followed up two patients who had precipitous drops during intravenous insulin therapy for diabetic ketoacidosis and hyperosmolar nonketotic state. the patient with diabetic ketoacidosis had a phosphate level nadir that equaled the lowest recorded phosphate level in a living human (0.03 mmol/l). because (1) serum phosp ...	1989	2730261
in vitro and in vivo comparison of the abilities of purine and pyrimidine 2',3'-dideoxynucleosides to inhibit duck hepadnavirus.	four purine and two pyrimidine 2',3'-dideoxynucleosides were studied for their ability to inhibit duck hepadnavirus replication. the purine 2',3'-dideoxynucleosides were more potent antiviral agents than the pyrimidine 2',3'-dideoxynucleosides. the concentration for 50% inhibition of viral replication (ic50) was determined for each of the effective agents. two drugs with low ic50s, 2,6-diaminopurine 2',3'-dideoxyriboside and 2',3'-dideoxyadenosine, were chosen for in vivo studies. animals receiv ...	1989	2729928
determination of plasma homocysteine by high-performance liquid chromatography with fluorescence detection.	severe homocystinemia is frequently associated with vascular disease while the pathological consequences of moderate or slightly elevated plasma homocysteine are unknown. cobalamin and folate deficiencies may result in an elevation of plasma homocysteine. a sensitive and reproducible assay for total plasma homocysteine has been developed. the essential steps in the assay include (i) conversion of homocysteine disulfides to free homocysteine with borohydride reduction; (ii) conjugation of homocys ...	2009	2729575
analytical determination of methylated histidine in proteins: actin methylation.	the methylation of histidine in actin from various muscle and nonmuscle sources has been studied by formation of phenylthiocarbamyl derivatives and subsequent reverse-phase high-pressure liquid chromatographic separation and analysis of actin hydrolyzates. all the actin species examined were found to contain 3-methylhistidine. this method has also been used in assays for the enzyme(s) responsible for methylation of rabbit skeletal muscle actin and to investigate the formation of other methylated ...	1989	2729572
fast elisa for measuring serum antibody responses.	a method which speeds up the enzyme-linked immunosorbent assay (elisa) is described. the procedure uses a modified falcon fast assay screening system (becton dickinson labware, lincoln park, nj) and falcon round-bottom 96-well plates. antigen is adsorbed onto beads which extend from a lid and fit into 96-well plates. the beads are washed in a trough and reacted to antibody in the round-bottom plate. the labor required to wash the plates after coating with antigen, antibody or conjugate is thereb ...	1989	2723439
immunoblotting analysis of the reaction of wildebeest, sheep and cattle sera with the structural antigens of alcelaphine herpesvirus-1 (malignant catarrhal fever virus).	malignant catarrhal fever (mcf) is a disease of cattle and some other ruminants caused by alcelaphine herpesvirus-1 (ahv-1), a virus of wildebeest. the disease also occurs in the absence of wildebeest and is then thought to be caused by a viral agent harboured by the sheep. the structural proteins of ahv-1 have been used as antigens for the immunoblotting analysis of sera from wildebeest, sheep and cattle infected by either ahv-1 or the "sheep-associated" form of the disease. wildebeest sera sho ...	1989	2718352
pica: a clue to iron deficiency anemia.		2009	2716310
management of acute asthma.		2009	2713796
near-miss asphyxiation from a toy ball: a small parts failure.	the case report of a near-fatal asphyxiation of an 11-month-old child by a 26 mm (diameter) toy ball is presented. the lack of compliance with existing consumer product safety commission standards for small parts is discussed, and a recommendation is made regarding the coloring of ingestible objects.	2009	2710666
a case of acute psychosis in temporal association with theophylline toxicity.		2009	2708558
thromboxane synthase activity and platelet function after furegrelate administration in man.	furegrelate sodium (u-63,557a), a pyridine-derivative thromboxane synthase inhibitor, was administered orally in single doses of 200 to 1600 mg to normal male subjects. furegrelate produced a dose-related inhibition of thromboxane synthesis for 8-12 hours when measured either ex vivo from platelet-rich plasma (prp) or in vivo from urine. in general, the extent of thromboxane synthesis inhibition was greater in prp than in urine. furegrelate significantly inhibited platelet aggregation, but the e ...	1989	2708549
the effect of n-3 polyunsaturated fatty acids on lipids, haemostasis, neutrophil and monocyte chemotaxis in insulin-dependent diabetes mellitus.	insulin-dependent diabetes mellitus (iddm) is associated with an increased risk of coronary artery disease (cad). there is some evidence that polyunsaturated fatty acids of the marine n-3 type (n-3 pufa's) may offer protection against cad. we have studied the effect of short-term dietary supplementation with n-3 pufas on lipids, haemostasis, neutrophil and monocyte chemotaxis in 10 patients with iddm. the patients were given 4 g daily of n-3 pufas (fish oil) for 6 weeks and were investigated bef ...	2008	2706043
penetrating eye injuries.	a review of all penetrating eye injuries treated at the manchester royal eye hospital over four years (1 january 1982-31 december 1985) was undertaken. a total of 202 penetrating eye injuries were seen of which 68 (34%) were in children under the age of 15 years. airgun, dart, and knife injuries accounted for 28 (41%) of the injuries. thirty seven patients (54%) achieved a good visual result (6/12 or better) and eight (12%) had enucleations. the period of inpatient treatment ranged from two to 1 ...	2009	2705791
[dynamics of bile secretion under stressful conditions].		2009	2702266
surrogate dentist: domestic medical guides and oral health care in the nineteenth century.		2009	2700922
[development of antibiotic resistance of type 1 shigella dysenteriae strains (shiga bacillus) isolated in tananarive on the east coast of madagascar].	from november 1988 to march 1989, 804 malagasy children stools were studied and 37 shigella strains isolated. 5 shigella dysenteriae type 1 from malagasy east coast (mananjary), presented a multiply resistance to ampicillin, carbenicillin, streptomycin, chloramphenicol, tetracycline, sulphonamides and trimethoprim. this last resistance has recently appeared in this area.	1989	2699224
[the etiological structure of shigellosis in the ussr in recent years].	the characterization of etiological structure of shigella infection in the whole of the ussr, in individual union republics and at a number of other administrative territories of the ussr in recent years is presented. s. flexneri has been shown to prevail at the territories with unsatisfactory water supply of the population, and s. sonnei prevails at the territories with good water supply. at the former territories s. dysenteriae and s. boydii retain their etiological importance, while at the la ...	1989	2698030
[demands for quality and planning standards for model casting].		2009	2697127
characterization and autoprocessing of precursor and mature forms of human immunodeficiency virus type 1 (hiv 1) protease purified from escherichia coli.	a recombinant plasmid encompassing the human immunodeficiency virus type 1 (hiv 1) protease coding sequence and flanking regions (ala-13 to gly-185 of the pol open reading frame) has been expressed in two distinct strains of escherichia coli, ar58 and ar68. in the first strain, ar58, the primary translation product, a 25 kilodalton (kda) precursor protein, is short-lived and rapidly processes itself to the 11 kda mature protease in vivo. in the second strain, ar68, the 25 kda species is only par ...	1989	2695927
[drug resistance of the causative agent of grigo'rev-shiga dysentery (shigella dysenteriae 1)isolated in the ussr].	forty strains of s. dysenteriae 1 isolated in the ussr within 1986-1988 were tested for their resistance to 11 antibacterial drugs. it was shown that 92.5-97.5 per cent of the isolates were resistant to chloramphenicol (cm) and tetracycline (tc), 22.5 per cent to streptomycin (sm), 17.5 per cent to nalidixic acid (nal) and 10 per cent to ampicillin (ap) and polymyxin (pm). resistance to cm tc (51.4 per cent) and cm tc nal (13.5 per cent) represented the predominating phenotype. 35 per cent of th ...	1989	2694989
[shigellosis in the ussr: the etiological role of shigella dysenteriae].	the etiological role of s. dysenteriae in shigella infections at different territories of the ussr in 1983-1987 is analyzed. the study shows that s. dysenteriae pertain to territories with unfavorable water supply of the population. at some of these territories, in particular the uzbek ssr, grigor'ev-shiga dysentery seems to gain ground and the restoration of the area of its spread occurs. in recent years the penetration of grigor'ev-shiga dysentery from abroad became more frequent in the presen ...	1989	2694693
falciparum malaria--present day problems. an experience with 425 cases.	clinical details and present day problems encountered in 425 cases of falciparum malaria (pf) are reported. 10.11% had taken chloroquine prior to reporting to us. parasitic count done in 23.05% cases lacked correlation with severity of disease. pattern of fever varied markedly but 5.4% were afebrile throughout and presented only with bodyache and malaise. apyrexial spell was noted in 5.64%. 28.70% had typical facial looks of anaemia and sallow complexion. cerebral symptoms were noted in 3.05%. o ...	1989	2693436
production of vero cytotoxin by escherichia coli and shiga toxin by shigella dysenteriae 1 as related to the growth medium and availability of iron.	six strains of escherichia coli producing vero cytotoxin (vtec) and six strains of shigella dysenteriae 1 were examined for the production of extra- and intracellular vero cytotoxin (vt) and shiga toxin respectively, in relation to the growth medium and availability of iron. vtec secreted less extracellular vt1 or vt2 when grown in trypticase soy broth (tsb) containing the iron chelator desferal, as compared to bacteria cultured in iron replete tsb. growth in tsb containing desferal resulted in ...	1989	2692581
[cataract surgery 220 years ago].	the author reports on the first 14 cataract extractions performed by karl kaspar von siebold, a würzburg surgeon, in 1766/67. he used daviel's method. at that time there was no anesthesia, no sterility or even antisepsis, and no optical correction of aphakia for his patients. four eyes were lost due to infection and another four had much poorer vision after surgery due to irregular corneal scarring. in six cases both patient and physician were satisfied with the result. siebold's case reports ex ...	2009	2689768
nutritional anestrus in beef cows: concentrations of glucose and nonesterified fatty acids in plasma and insulin in serum.	twenty-two nonlactating hereford cows exhibiting normal estrous cycles were fed either maintenance (m) or restricted (r) diets until most of the r cows became anestrus; r cows then were fed 160% of the m diet until estrous cycles resumed. concentrations of progesterone, glucose, insulin and nonesterified fatty acids (nefa) were determined in weekly blood samples. blood also was collected frequently, before and after i.v. infusion of 300 ml of a 40% glucose solution, to evaluate responses in bloo ...	1989	2689418
purification of shiga toxin by alpha-d-galactose-(1----4)-beta-d-galactose-(1----4)-beta-d-glucose-(1- ---) receptor ligand-based chromatography.	a simple and rapid method for shiga toxin purification based on specific binding to the gal alpha 1----4gal beta 1----4glc globotrioside trisaccharide covalently linked to polyacryl/polyvinyl (fractogel) has been developed. a cell-free sonicate-filtrate of shigella dysenteriae type 1, strain 114sd was passed over the globotrioside-fractogel column, and bound toxin eluted with 6 m guanidine-hcl. a yield of 36 mg pure toxin/1 sonicate-filtrate was obtained, i.e. a one step 1224-fold purification. ...	1989	2689221
assay for sialidase using erythrocytes and peroxidase-labeled peanut lectin.	a rapid and sensitive sialidase assay method based on peroxidase-labeled peanut lectin (pna) binding to desialylated erythrocyte is described. formalinized sheep erythrocytes were used both as a stable substrate for sialidase and as a target for the lectin. in the case of sialidases from vibrio cholerae and arthrobacter ureafaciens, a linear relationship was observed between the amount of peroxidase-labeled pna bound to erythrocytes and the enzyme amount. binding of the lectin to sialidase-treat ...	1989	2688936
problems associated with the use of immediately dangerous to life and health (idlh) values for estimating the hazard of accidental chemical releases.	the possibility of accidental industrial chemical releases has generated considerable recent attention. one area requiring research for emergency planning is the development of safe exposure concentrations for the public in the event of an inadvertent release. the united states environmental protection agency (epa) has established a list of extremely hazardous substances and suggested that the toxicity ranking for 92 hazardous materials could be based on the "immediately dangerous to life or hea ...	2009	2688389
monoclonal antibodies against the surface antigens of shigella flexneri serotype 1b and shigella dysenteriae serotype 1.	monoclonal antibodies against the surface antigens of shigella flexneri 1b and s. dysenteriae 1 were prepared. the specificities of the antibodies were evaluated by enzyme-linked immunosorbent assay (elisa), and quantitative agglutination using microtiter plate. monoclonal antibodies against s. flexneri 1b, designated sf2b2 and sf2g4, belonged to igg2a and igg1 subclass, respectively. the former was specific for s. flexneri 1b, whereas the latter was reactive not only to s. flexneri 1b, but also ...	1989	2687648
recent advances in gastrointestinal malignancy.		2008	2686527
recent advances in gastrointestinal malignancy.		2008	2686527
[cellular lectin binding sites in the human retinal pigment epithelium and photoreceptors--method of lectin histochemistry and results with peroxidase marked lectins in paraffin sections].	lectins are sugar-binding proteins or glycoproteins which bind to specifically complementary sugar residues found in cell membranes and the cytoplasm. lectin-binding sites are determined by histochemical methods. cellular lectin-binding sites change with morphological and functional alterations of the cell, and the determination of lectin receptors can be used to identify specific cell types in histological sections. lectin-binding sites of the human retinal pigment epithelium (rpe) and photorec ...	1989	2684825
corticosteroids in homeostasis.		2008	2683585
corticosteroids in homeostasis.		2008	2683585
thymotaxin, a chemotactic protein, is identical to beta 2-microglobulin.	thymotaxin, an 11-kilodalton protein chemotactic for rat bone marrow hematopoietic precursors, was purified from media conditioned by a rat thymic epithelial cell line. the nh2-terminal sequence of thymotaxin was identical to that of rat beta 2-microglobulin (beta 2m). antibodies to beta 2m removed thymotaxin activity from the fraction containing the 11-kilodalton protein. chemotactic activity was observed with rat plasma beta 2m, human beta 2m, and mouse recombinant beta 2m, further supporting ...	1989	2683083
sonographic and pathological staging of patients with clinically localized prostate cancer.	we evaluated 64 patients with clinically localized prostate cancer (on the basis of rectal examination, serum acid phosphatase, bone scan and pelvic computerized tomography scan) by transrectal sonography before radical prostatectomy. of the 48 patients with histologically proved localized prostate cancer sonography overstaged the disease in 5 (10%) and correctly staged it in 43 (90%). all overstaged cancer patients were scanned after either prostatic biopsy (4) or transurethral prostatectomy (1 ...	2009	2681836
regulation of plasminogen activators and their inhibitors in rheumatic diseases: new understanding and the potential for new directions.	over the past several years there has been a rapid expansion in our understanding of the fibrinolytic system. this includes knowledge of the components, availability of recombinant reagents and a better understanding of the regulation of fibrinolysis in health and disease. disturbances in the regulation of the balance between fibrin deposition and removal have been implicated in a number of inflammatory diseases including certain rheumatic diseases. this overview summarizes our knowledge of the ...	2009	2681762
captopril--nifedipine interaction in hypertension.	nifedipine, a calcium channel blocker exerts significant peripheral vasodilatory activity in hypertensive patients. it has been postulated that the antihypertensive effect of peripherally acting vasodilators is masked, by counter regulatory mechanism e.g. activation of renin-angiotensin aldosterone (raa) axis. the present work was undertaken to study the effect of blockade of raa axis using captopril, an angiotensin converting enzyme inhibitor on the blood pressure lowering activity of nifedipin ...	2009	2681136
normal catch-up growth in rats severely food-restricted prior to lesions of the dorsomedial hypothalamic nucleus: the first 48 hours.	following a brief period of ad lib (al) feeding, 45-day-old male sprague-dawley rats were either fed al or food-restricted (rest) for 21 days to 50% of the intake of the al rats. at this time, some al and some rest rats received electrolytic lesions in the dorsomedial hypothalamic nuclei (dmnl), whereas other al and rest rats were sham-operated (con). following this, all rats were refed (ref) al and killed two days later. at this time, dmnl-rest + ref and dmnl-al weighed as much as con-rest + re ...	1989	2678164
isolation and characterization of functional shiga toxin subunits and renatured holotoxin.	shiga toxin is a protein toxin produced by shigella dysenteriae type i strains. in this report we present a procedure for the separation of functionally intact toxin a and b chains and for their reconstitution to form biologically active molecules. in agreement with the findings of others, the isolated a chain was shown to be a potent in vitro inhibitor of eukaryotic protein synthesis. the isolated b chain bound to hela cells and competitively inhibited the binding and cytotoxic activity of holo ...	1989	2677606
[clinico-pathogenetic correlations in acute infectious diarrhea].		2009	2675261
lymphocyte homing.	the phenomenon of "homing" is discussed with respect to patterns of lymphocyte circulation and the molecules on the surface of both endothelium and lymphocytes that mediate this process. in addition, the data are analysed in the context of a model for lymphocyte homing.	1989	2675225
clinical & bacteriological profiles of shigellosis in calcutta before & after an epidemic (1984-87).	patients below 5 yr of age, hospitalised for shigellosis over a period of four years (1984-87), were studied. during the epidemic of bacillary dysentery (1984) isolation of different shigella spp. as well as shigella dysenteriae type 1 was high. decreased isolation of sh. dysenteriae type 1 and increased isolation of sh. flexneri was observed during post-epidemic years (1985-87). isolation of different shigella spp. was always above 25 per cent from patients with dysentery and greater than 7 per ...	1989	2674001
mechanisms of tumor induction by human retroviruses.	oncogenesis can be induced by chronic and acute rna tumor viruses through a promoter/enhancer insertion mechanism and through a transforming protein coded by a viral oncogene (v-onc), respectively. a hypothetical trans-activating mechanism is invoked by retroviruses with trans-activating regulatory proteins. so far, in humans only htlv-i has been firmly linked to a malignancy. the same virus is also implicated in slowly progressing neurological disorders. except for transformation by viral oncog ...	1989	2673254
antibiotics in the management of shigellosis in children: what role for the quinolones?	in the last 20 years, epidemic bacillary dysentery due to shigella dysenteriae type 1 has become an important cause of serious morbidity and death in children less than 5 years of age in a number of developing countries; in many instances the infecting strains have been resistant to many or all of the usually recommended antibiotics. moreover, an increasing proportion of shigella strains of other serotypes isolated in all parts of the world are now resistant to the most commonly used antibiotics ...	1989	2672246
hodgkin's disease and non-hodgkin's lymphomas.		2009	2670408
diagnosis of pancreatic carcinoma by fine needle aspiration cytology and computerized cytomorphometry.	eighty-one fine needle aspirations (fnas) of pancreatic masses were performed between 1980 and 1988. histologic or clinical follow-up was available for correlation with 78 aspirates. the fna cytologic diagnosis of pancreatic carcinoma had a sensitivity of 79% and a specificity of 91%. fifteen of the fna specimens were examined with the zeiss ibas image analysis system to determine nuclear area, form (shape), diameter, density and integrated optical density (iod). nuclear area and iod correlated ...	2007	2669782
[bacillary dysentery--1987].		1989	2669032
hemolytic uremic syndrome and diarrhea in argentine children: the role of shiga-like toxins.	shiga-like toxin-producing escherichia coli have been associated with hemorrhagic colitis and the hemolytic uremic syndrome (hus). because argentina has the highest reported frequency of hus in the world, argentine children were prospectively studied during the hus seasons for evidence of shiga-like toxin-related diseases. on the basis of serology, fecal cytotoxin neutralization, stool cultures, and dna hybridization of colony lysates, most children with hus had evidence of infection with shiga- ...	1989	2668430
purification, crystallization, and preliminary x-ray diffraction studies of the flavoenzyme mercuric ion reductase from bacillus sp. strain rc607.	the flavoenzyme mercuric ion reductase from bacillus sp. strain rc607 was purified by dye-ligand affinity chromatography. the protein was crystallized from solutions of high ionic strength, and one of the two crystal forms obtained has proven suitable for x-ray diffraction studies. preliminary analysis showed that these crystals belong to the tetragonal space group 1422. the unit cell dimensions are a = b = 180.7 a; c = 127.9 a. the diffraction pattern extends to better than 3 a resolution. crys ...	1989	2668287
cryptococcus neoformans in the seminal fluid of an aids patient. a contribution to the clinical course of cryptococcosis.	in a 33-year-old hiv-positive homosexual male suffering from unexplained headache, cryptococcosis was diagnosed in a progressive secondary stage. after treatment with the standard combination therapy of amphotericin b + flucytosine for 34 d, the patient was clinically symptom-free and discharged, upon his own request, from the hospital. he remained under ambulatory mycological control. after an interval of 65 d during which the urine had been free from cryptococcus neoformans (cr.n.), the fungus ...	1989	2666852
use of monoclonal antibodies to type shigella flexneri in bangladesh.	a panel of 10 mouse and rat monoclonal antibodies specific for different type- and group-specific o-antigenic determinants of shigella flexneri lipopolysaccharide was used to serotype 240 isolates of s. flexneri from bangladesh. three immunoglobulin m antibodies were used in a direct slide agglutination test; seven immunoglobulin g antibodies were absorbed to staphylococcus aureus and used in a coagglutination assay. all but 13 of the isolates could be serotyped by using the monclonal antibodies ...	1989	2666435
rapid method to detect shiga toxin and shiga-like toxin i based on binding to globotriosyl ceramide (gb3), their natural receptor.	shiga toxin and the closely related shiga-like toxins produced by escherichia coli represent a group of very similar cytotoxins that may play an important role in diarrheal disease and hemolytic uremic syndrome. these toxins have the same biologic activities and according to recent studies also share the same binding receptor, globotriosyl ceramide (gb3). they are currently detected, on the basis of their ability to damage several cell lines, by using expensive and tedious assays that require fa ...	1989	2666433
griseofulvin and ketoconazole in the treatment of dermatophyte infections.		2009	2666321
species differences in the pharmacology of terminal 5-ht autoreceptors in mammalian brain.		2009	2665245
introduction to immunocytochemistry.	immunocytochemistry has opened a new era in research and diagnosis. the development of immunocytochemical methods has made it possible to identify in situ normal and pathological tissue constituents, which it has not been possible to detect using ordinary histological methods. however, immunocytochemical techniques involve several pitfalls, which without proper control protocols can easily lead to incorrect findings. when interpreting the results obtained, account must always be taken of the mor ...	2009	2664772
congo red-mediated regulation of levels of shigella flexneri 2a membrane proteins.	the ability of shigella spp. to bind congo red from agar medium is generally correlated with their virulence properties. we used a metabolically active culture of shigella flexneri 2a to determine the effect of congo red on its membrane protein profiles. virulent s. flexneri grown in the presence of congo red at 37 degrees c showed increased levels of three proteins with mrs of 43,000, 58,000, and 63,000 (43k, 58k, and 63k proteins) in the sarkosyl-soluble membrane fractions. the observed phenom ...	1989	2663721
quantitation of the rabbit intestinal glycolipid receptor for shiga toxin. further evidence for the developmental regulation of globotriaosylceramide in microvillus membranes.	shiga toxin, produced by shigella dysenteriae 1, causes enterotoxic, cytotoxic, and neurotoxic effects, which may be mediated by a glycolipid receptor, globotriaosylceramide, gb3. to study the relationship of this receptor and toxin effects, globotriaosylceramide was quantitated and further characterized in rabbit small intestinal microvillus membranes at various ages. glycolipids were extracted from rabbit microvillus membranes, purified on unisil columns, and quantitated by high-performance li ...	1989	2663611
epidemic shigellosis due to shigella dysenteriae type 1 in south asia.		1989	2661420
intraoperative staging in ovarian cancer.	in patients with early stage i or ii ovarian cancer a meticulous staging laparotomy is required; this should include omentectomy, pelvic and paraaortic lymphadenectomy, multiple peritoneal biopsies and diaphragmatic biopsies. adjunctive therapy is based on these surgical-pathological findings. in patients with advanced disease (stages iii and iv) it has been demonstrated that optimal tumour reduction enhances the length of survival. a complete resection of all gross disease in the abdominal cavi ...	2009	2661086
secretory immunoglobulin a response to shiga toxin in rabbits: kinetics of the initial mucosal immune response and inhibition of toxicity in vitro and in vivo.	although the role of shiga toxin in dysentery is unknown, the toxin is cytotoxic to hela cells, causes fluid secretion in rabbit intestine, and is lethal to rabbits and mice when injected parenterally. in the present study, rabbits received three weekly doses of shiga toxin directly into chronically isolated ileal loops. within a week, secretions from these loops contained immunoglobulin a (iga) anti-shiga toxin. the titer of iga anti-shiga toxin increased after weekly doses 2 and 3. little igg ...	1989	2659525
development of nephrology nursing care in europe: 1978-1988.	nephrology nursing care in europe has been accelerated by medical and technical advances. nurses are becoming more and more involved in decision-making processes as opposed to the traditional serving role. this article analyzes some aspects responsible for these changes in europe from 1978-1988 and how nephrology nurses adapted to these developments.	2007	2658872
ct of intra-abdominal fluid collections.	a wide variety of fluids including ascites, blood, pus, urine, bile, lymph, chyle, mucin, and cerebrospinal fluid can accumulate within the peritoneal and pelvic cavities. the location, appearance, and distribution of this fluid is governed by a number of anatomic and gravitational factors that when carefully analyzed, can help to reveal their source and etiology. computed tomography is ideally suited to document the presence of abdominal and pelvic fluid collections; display their location and ...	2008	2657846
[clinical features of overseas travellers' infectious enteritis admitted in the hospitals for infectious diseases].		1989	2657133
[survey on overseas traveller's diarrhea at narita airport quarantine station--the species of bacteria isolated and the suspected countries for infection].		1989	2657132
inoculum size in shigellosis and implications for expected mode of transmission.		1989	2656880
unusual nucleotide arrangement with repeated sequences in the escherichia coli k-12 chromosome.	between 59 and 60 min on the escherichia coli genetic map, there is a highly conserved sequence of 29 base pairs, containing an inverted repeat of seven base pairs that appears 14 times, 32 or 33 base pairs apart, downstream of the iap gene coding region. about 24 kilobase pairs downstream of the 14 repeats, a similar 29-base-pair sequence with a spacing of 32 base pairs appears seven times. nucleotide sequences hybridizing with the 29-base-pair fragment were also detected in shigella dysenteria ...	1989	2656660
malignant hyperpyrexia.		1989	2653537
interaction of shigella toxin with globotriaosyl ceramide receptor-containing membranes: a fluorescence study.	the interaction of the b-subunit of shigella toxin with a globotriaosyl ceramide receptor incorporated into phosphatidylcholine vesicles was studied by fluorescence spectroscopy. from the position of the maximum in the emission spectrum and the accessibility to acrylamide quenching, it is concluded that a single tryptophan of a free b-chain is located in a highly polar environment, most likely on the surface of the folded polypeptide chain. binding of b-subunits to the membrane-associated globot ...	1989	2653314
[anxiety and the presence of the father at childbirth].	the authors give a report of a follow-up the anxiety of 363 couples whereby the husband decided to be present at the childbirth and took part in the childbirth preparation courses. the anxiety state and anxiety trait in men was found to be significantly lower than in women. the data of women were compared to a matched control group consisting of 135 pregnant women. in cases where the husband was present at childbirth the anxiety state and anxiety trait of the women was considerably lower than in ...	2007	2652033
pathogenesis of shigella diarrhea. xiv. analysis of shiga toxin receptors on cloned hela cells.	binding kinetics of shiga toxin to hela ccl-2 cells and to cell lines cloned by limiting dilutions were determined. lines with a wide range of sensitivity to shiga toxin were obtained. binding data, analyzed by a computer-based scatchard model program, revealed two classes of binding sites, one of low affinity and high capacity and one of high affinity and low capacity. the number of high affinity, but not low affinity, sites present on the clones correlated with their sensitivity to toxin. tuni ...	1989	2651533
renin: endocrine, paracrine, or part-paracrine control of blood pressure?		1989	2650710
lead toxicity and iron deficiency in utah migrant children.	we determined the frequency of presumptive iron deficiency and lead toxicity in 198 utah migrant children, ages 9-72 months, during the summer of 1985. there were no confirmed cases of lead toxicity. thirteen per cent of those tested and 30 per cent of the children ages 9-23 months were iron deficient. hematocrit determinations accurately predicted iron deficiency in only 35 per cent of the children confirmed to have this disorder via erythrocyte protoporphyrin screening.	2009	2650572
lead toxicity and iron deficiency in utah migrant children.	we determined the frequency of presumptive iron deficiency and lead toxicity in 198 utah migrant children, ages 9-72 months, during the summer of 1985. there were no confirmed cases of lead toxicity. thirteen per cent of those tested and 30 per cent of the children ages 9-23 months were iron deficient. hematocrit determinations accurately predicted iron deficiency in only 35 per cent of the children confirmed to have this disorder via erythrocyte protoporphyrin screening.	2009	2650572
a sonographic and karyotypic study of second-trimester fetal choroid plexus cysts.	a prospective study was undertaken of 513 women between 15.6-24.1 weeks' gestation who had a level ii ultrasound examination followed immediately by a genetic amniocentesis. the presence or absence of fetal choroid plexus cysts was noted and the results correlated with the fetal karyotype. thirteen cases of choroid plexus cysts were observed sonographically, a prevalence of 2.5%. the size of the cysts ranged from 3-10 mm, with a median of 6 mm. there were no other sonographically detectable cong ...	2009	2649818
plasmid dna analysis by agarose gel electrophoresis on an epidemic-associated strain of trimethoprim resistant shiga's bacillus from gimira wereda (keffa administrative region, southwest ethiopia).	a combination of genetic mating experiments and plasmid dna analysis by gel electrophoresis was carried out on an epidemic-associated shiga's bacillus with resistance type acssuttp, isolated in 1983 from gimira wereda, keffa administrative region, south west ethiopia. the donor strain contained 9 plasmid species. their sizes in megadaltons (mdal) were: 120, 40, 35, 12.5, 6.0, 5.1, 4.3, 2.5 and 1.7. analysis of escherichia coli k12 transconjugants revealed that the 40, 35, and 4.3 mdal plasmids c ...	1989	2646117
introduction and spread of multi-resistant shigella dysenteriae i in thailand.	outbreaks of shigella dysenteriae i occurred in northeastern thailand in the fall of 1986 and again in the spring and fall of 1987 for the first time in over 20 years. the epidemic strain of s. dysenteriae i was resistant to tetracycline, streptomycin, chloramphenicol, and trimethoprim-sulfamethoxazole, but susceptible to ampicillin. trimethoprim resistance was chromosomally encoded by type i dihydrofolate reductase. in ubon province, where 10,000 cases of dysentery were reported, there were 3-5 ...	1989	2644859
detection of enterotoxigenic escherichia coli after polymerase chain reaction amplification with a thermostable dna polymerase.	the direct identification of enterotoxigenic escherichia coli from clinical specimens was examined by using the polymerase chain reaction (pcr) for amplifying the heat-labile toxin (lt) gene. two synthetic primers, each of which was 20 bases in length, were used with the thermostable dna polymerase from thermus aquaticus to amplify the lt gene. the amplified pcr products were detected by either gel electrophoresis or hybridization to a 24-base synthetic oligonucleotide probe conjugated to alkali ...	1989	2644292
bilateral torsion of the normal ovary and oviduct in a young girl.		2008	2643670
bilateral torsion of the normal ovary and oviduct in a young girl.		2008	2643670
[serological diagnosis of campylobacter jejuni infections].	antibody level to campylobacter in 28 sera of patients of whom campylobacter infection was confirmed by germ isolation from feces was tested. the investigation was performed using passive haemagglutination technique and as antigens heated and acid glycine extraction prepared from homologous and reference strains. for the method used the heated antigen proved to be superior. out of 28 tested patients of whom 92.8% were children, 8 sera were positive, 9 doubtful and 9, derived mainly from neonates ...	1989	2640683
[clinical-experimental examinations on phonetic function in edentulous patients and after insertion of total prostheses measured by the s-sound realization].	lose of teeth and therapy by prosthesis interfering with the oral sectors that are necessary for s-sound articulation have an important influence on s-sound realization. hitherto, the resulting s-sound changes used to be evaluated only from a subjective point of view. the application of a complex measuring technique for s-sound analysis permitted to determine the influence of the upper and lower jaw plates on s-sound formation by experiments. in another series of experiments, it was shown that e ...	2008	2640388
any more cordials to the drooping spirit? professional ethics, 1847-1989.		2009	2636862
[detection of streptococci from various serological groups in animals].	during the period from 1985 to 1988 we determined 228 strains of streptococci isolated from samples of various sorts of biomaterials, mainly animals. from this set of streptococci we classified 207 strains into serological groups according to the lancefield classification and about 30% strains into species by means of serological and biochemical methods. most of the strains were allocated to group c (37.28%) and group q (17.39%). 89 streptococci strains originated from pigs, 40 strains from hors ...	1989	2631378
isolation of inhibitors of adenylate cyclase from dan-shen, the root of salvia miltiorrhiza.	the effect of dan-shen extract, the root of salvia miltiorrhiza, on adenylate cyclase was investigated in both rat brain and rat erythrocytes. the etoac fraction of the meoh extract was proved to have significant inhibitory activity. potent inhibitory principles in the etoac fraction were isolated and identified as 4 polyphenolic acids, rosemarinic acid, lithospermic acid, and their methyl ester derivatives.	1989	2630095
[diagnostic value of cranial computerized tomography in pediatric practice].	a total of 100 clinical records have been studied to as certain the diagnostic use of brain ct. most frequent diagnoses are: hypoxic-ischemic encephalopaty, seizure disorders, psychomotor delay, head enlargement and trauma. the first years of life was the period with a higher frequency of applications and the greater percentage of pathologic results (75-80 por 100) was found among intracranial hypertension, fetal distress, macrocephaly or infections of central nervous system and their sequelae. ...	2008	2629553
[meta-analysis. a systematic approach to the synthesis of knowledge].		2008	2620806
[meta-analysis. a systematic approach to the synthesis of knowledge].		2008	2620806
indomethacin blocks the anorexic action of interleukin-1.	it has been reported recently that the central nervous system actions of interleukin-1 are mediated by the prostaglandin system in the brain. the present study was therefore performed in order to examine the hypothesis that indomethacin, an inhibitor of prostaglandin biosynthesis, might alleviate the interleukin-1-induced suppression of food intake in rats. the i.p. injection of interleukin-1 (2 micrograms/rat) resulted in a significant decrease in food intake. the pre-injection of indomethacin ...	1989	2620696
indomethacin blocks the anorexic action of interleukin-1.	it has been reported recently that the central nervous system actions of interleukin-1 are mediated by the prostaglandin system in the brain. the present study was therefore performed in order to examine the hypothesis that indomethacin, an inhibitor of prostaglandin biosynthesis, might alleviate the interleukin-1-induced suppression of food intake in rats. the i.p. injection of interleukin-1 (2 micrograms/rat) resulted in a significant decrease in food intake. the pre-injection of indomethacin ...	1989	2620696
[nursing career development program by private industry--from job management to career management].		2009	2615507
wisc-r stability and re-evaluation of learning-disabled students.	this study investigated the temporal stability of wisc-r iq scores for learning-disabled subjects (n = 113). all study subjects were administered the wisc-r for an initial evaluation (m age = 8 years, 3 months) and a follow-up re-evaluation (m age = 11 years, 7 months). pearson product-moment correlations yielded coefficients that were considerably lower than those previously reported: r = .55, p less than .001 for the verbal iqs; r = .63, p less than .001 for the performance iqs; and r = .58, p ...	2008	2613906