Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
|---|
| [enhancement of norovirus detection rates in oysters and other food samples by using bacterial treatment]. | factors such as low recovery rate and food contaminants may be responsible for the difficulty of detecting norovirus (nv) by pcr in foodborne outbreaks. to detect nv more efficiently, we introduced a bacterial treatment, in which concentrated samples were incubated overnight with klebsiella oxytoca at 35 degrees c before rna extraction using the standard protocol. recovery rates of nvs (g i/8 or g ii/13) added to food suspensions in the modified method were compared with those in the standard me ... | 2008 | 19155597 |
| characterization of blakpc-containing klebsiella pneumoniae isolates detected in different institutions in the eastern usa. | the emergence of bla(kpc)-containing klebsiella pneumoniae (kpc-kp) isolates is attracting significant attention. outbreaks in the eastern usa have created serious treatment and infection control problems. a comparative multi-institutional analysis of these strains has not yet been performed. | 2009 | 19155227 |
| microbial aetiology of acute clinical mastitis and agent-specific risk factors. | a nation wide study on the microbial aetiology of cases of acute clinical mastitis in swedish dairy cows was conducted with the aim to investigate changes in the microbial panorama compared to a previous study performed 1994-1995. another aim was to investigate some agent-specific environmental and individual risk factors. milk samples were collected from 987 udder quarter cases from 829 cows during six 2-month periods from may 2002 to april 2003, and data on risk factors and demography were col ... | 2009 | 19155148 |
| extended-spectrum beta-lactamase-producing pathogens in a children's hospital: a 5-year experience. | pediatric infection with bacteria producing extended-spectrum beta-lactamases (esbls) has not been well described. we sought to determine the proportion of isolates producing esbls and the incidence of infection or colonization with these organisms in our tertiary care pediatric facility over 5 years. in addition, we sought to evaluate the characteristics of children affected. | 2009 | 19155096 |
| a low-temperature thermoplastic anti-bacterial medical orthotic material made of shape memory polyurethane ionomer: influence of ionic group. | pcl-based shape memory polyurethane ionomers with quaternarized pyridine moieties incorporated through molecular extension were synthesized. these polyurethanes were specifically designed as low-temperature thermoplastic anti-bacterial orthotic materials. a commercialized orthotic material was employed for comparison. the influence of ionic groups on the properties of orthotic materials was studied. the anti-bacterial properties and cytotoxicity of the polyurethane ionomer were tested. it was fo ... | 2009 | 19154670 |
| klebsiella meningoencephalitis presenting like embolic ischemic stroke. | 2009 | 19153636 | |
| characterization of glycerol dehydratase expressed by fusing its alpha- and beta-subunits. | the gdh and gdhr genes, encoding b(12)-dependent glycerol dehydratase (gdh) and glycerol dehydratase reactivase (gdhr), respectively, in klebsiella pneumoniae, were cloned and expressed in e. coli. part of the beta-subunit was lost during gdh purification when co-expressing alpha, beta and gamma subunit. this was overcome by fusing the beta-subunit to alpha- or gamma-subunit with/without the insertion of a linker peptide between the fusion moieties. the kinetic properties of the fusion enzymes w ... | 2009 | 19152074 |
| population variability of the fimh type 1 fimbrial adhesin in klebsiella pneumoniae. | fimh is an adhesive subunit of type 1 fimbriae expressed by different enterobacterial species. the enteric bacterium klebsiella pneumoniae is an environmental organism that is also a frequent cause of sepsis, urinary tract infection (uti), and liver abscess. type 1 fimbriae have been shown to be critical for the ability of k. pneumoniae to cause uti in a murine model. we show here that the k. pneumoniae fimh gene is found in 90% of strains from various environmental and clinical sources. the fim ... | 2009 | 19151141 |
| antibacterial and antitumorigenic properties of microcin e492, a pore-forming bacteriocin. | microcins are a family of low-molecular weight bacteriocins produced and secreted by gram-negative bacteria. this review is focused on microcin e492, a pore-forming bacteriocin produced by klebsiella pneumoniae ryc492 that exerts its antibacterial action on related strains. the steps necessary for the production of active microcin e492 involve post-translational modification with a catechol-type siderophore at the c-terminal and proteolytic processing during export to the extracellular space. th ... | 2009 | 19149591 |
| [antibiotic resistance rates of extended spectrum beta-lactamase producing escherichia coli and klebsiella spp. strains isolated from urinary tract infections in a private hospital]. | the aim of this study was to detect the antibiotic resistance rates of extended spectrum beta-lactamase (esbl) producing escherichia coli and klebsiella spp. strains isolated from urinary tract infections (utis) in private acibadem hospital, istanbul, turkey. a total of 1100 e. coli and 356 klebsiella spp. strains isolated from 17.028 urine cultures which were processed between october 2006 and august 2007 in the clinical laboratory, were included to the study. identification of bacteria and ant ... | 2008 | 19149097 |
| [investigation of plasmid-mediated ampc beta-lactamase types in klebsiella spp. and escherichia coli isolates resistant or intermediate to cefoxitin]. | plasmid mediated ampc beta-lactamases are reported from enterobacteriaceae with increasing frequency. there have been reports of treatment failures in patients infected with these organisms and given broad-spectrum cephalosporins. the aim of this study was to investigate the presence of plasmid mediated ampc beta-lactamases in escherichia coli and klebsiella spp. a total of 41 strains of cefoxitin resistant or intermediate e. coli (n= 27) and klebsiella spp. (n= 14) were collected from january 2 ... | 2008 | 19149075 |
| [resistance to newer beta-lactams and related esbl types in gram-negative nosocomial isolates in turkish hospitals: results of the multicentre hitit study]. | increasing resistance due to extended-spectrum beta-lactamases (esbls) and multiple resistance mechanisms in gram-negative hospital isolates restrict the role of beta-lactam antibiotics in empirical treatment of serious infections. as the prevalence of esbl producing strains and resistance rates to antimicrobial agents can vary in each center, local surveillance studies are required to guide therapy. in this study, in vitro rates of resistance to ceftriaxone, ceftazidime, cefepime, imipenem, cef ... | 2008 | 19149074 |
| risk factors for colonisation of newborn infants during an outbreak of extended-spectrum beta-lactamase-producing klebsiella pneumoniae in an intermediate-risk neonatal unit. | we describe a cross-sectional survey to identify risk factors for colonisation of neonates by extended-spectrum beta-lactamase (esbl)-producing klebsiella pneumoniae. this occurred following exposure to a colonised healthcare worker during an outbreak in an intermediate-risk neonatal unit. in total, 120 neonates admitted consecutively during a three-month period were screened for esbl-producing k. pneumoniae by rectal swabbing and 27 were identified as colonised. multivariate analysis showed col ... | 2009 | 19147256 |
| rhinoscleroma of the sinuses. | rhinoscleroma is a rare chronic, granulomatous disease of the respiratory tract. | 2008 | 19146007 |
| antimicrobial activity of some water plants from the northeastern anatolian region of turkey. | the antimicrobial activity of methanol and acetone extracts of butomus umbellatus, polygonum amphibium, and two species of the genus sparganium (s. erectum and s. emersum)against three gram-positive, five gram-negative bacteria and one fungus was assessed by the disk diffusion method. the microorganisms used were staphylococcus aureusatcc-29740, escherichia coli atcc-25922, pseudomonas aeruginosa atcc-15442, salmonella typhi nctc-9394, klebsiella pneumoniae nctc-5046, proteus vulgaris atcc-7829, ... | 2009 | 19145212 |
| enteric fever-like syndrome caused by raoultella ornithinolytica (klebsiella ornithinolytica). | 2009 | 19144809 | |
| specificity of ertapenem susceptibility screening for detection of klebsiella pneumoniae carbapenemases. | detection of klebsiella pneumoniae carbapenemases (kpcs) can be nonspecific, especially when kpcs are uncommon. we determined the positive predictive value and specificity of ertapenem resistance for kpc detection in 2,696 enterobacteriaceae isolates. the positive predictive value and specificity of ertapenem resistance for kpc detection were 74% and 99.2%, respectively. | 2009 | 19144799 |
| antimicrobial property of a herbal preparation containing dalbergia sissoo and datura tramonium with cow urine against pathogenic bacteria. | in this study, a herbal preparation containing dalbergia sissoo and datura stramoium with cow urine (dsds), was evaluated for its antibacterial potential against pathogenic strains of gram-positive (staphylococcus aureus and streptococcus pneumoniae) and gram-negative (escherichia coli, pseudomonas aeruginosa and klebsiella pneumoniae) bacteria. antibacterial activity was compared to standard antibiotic drugs i.e. chloramphenicol (30 mcg), ampicillin (10 mcg), nalidixic acid (10 mcg) and rifampi ... | 2008 | 19144288 |
| strongyloides stercoralis: a cause of morbidity and mortality for indigenous people in central australia. | strongyloides stercoralis may cause a complicated infection in immunocompromised patients, which has a high case fatality rate. death generally results from sepsis with enteric pathogens. globally, infection with the human t-cell lymphotropic virus type 1 (htlv-1) is a major risk factor for this syndrome. both s. stercoralis and htlv-1 are endemic to central australia. | 2008 | 19143887 |
| [antimicrobial activity of soft and purified propolis extracts]. | to evaluate the antimicrobial activity of soft and purified propolis extracts. study object and methods: antimicrobial activity of soft and purified propolis extracts was determined with reference cultures of staphylococcus aureus atcc 25923, enterococcus faecalis atcc 29212, escherichia coli atcc 25922, klebsiella pneumoniae atcc 33499, pseudomonas aeruginosa atcc 27853, proteus mirabilis atcc 12459, bacillus subtilis atcc 6633, bacillus cereus atcc 8035, and fungus candida albicans atcc 60193. ... | 2008 | 19142056 |
| [antimicrobial spectrum of antibiotic batumin]. | antibacterial activity of antibiotic batumin, isolated from pseudomonas genus has been studied using clsi standard methods. batumin was highly active against all studied strains belonging to 10 species of staphylococcus genus (minimal inhibitory concentration (mic)--0.25-0.5 microg/ml); it has shown a moderate activity against enterobacteria of genera salmonella, bordetella, escherichia, klebsiella (mic 8-64 microg/ml) and practically did not inhibit strains ofmicrococci, streptococci, sporeform ... | 2008 | 19140420 |
| klebsiella pneumoniae deep neck infection with acute necrotizing esophagitis. | 2009 | 19139686 | |
| bacteremia coexisting with tophaceous gout of the spine mimicking spondylodiscitis: a case report. | a case report and review of the literature. | 2009 | 19139655 |
| gas-forming brain abscess caused by klebsiella pneumoniae. | gas forming brain abscess is a rare disease caused by klebsiella pneumoniae occurring in patients with impaired host defense mechanism such as diabetes mellitus or liver cirrhosis. a 59-year-old man with 2-year history of diabetes mellitus and 20-year history of liver cirrhosis presented to the hospital with headache. on the day after admission, severe headache was developed and he deteriorated rapidly. brain ct showed a non-enhanced mass including multiple air density as well as surrounding ede ... | 2008 | 19137083 |
| ampc beta-lactamases. | summary: ampc beta-lactamases are clinically important cephalosporinases encoded on the chromosomes of many of the enterobacteriaceae and a few other organisms, where they mediate resistance to cephalothin, cefazolin, cefoxitin, most penicillins, and beta-lactamase inhibitor-beta-lactam combinations. in many bacteria, ampc enzymes are inducible and can be expressed at high levels by mutation. overexpression confers resistance to broad-spectrum cephalosporins including cefotaxime, ceftazidime, an ... | 2009 | 19136439 |
| infection outcomes in splenectomized patients with hemoglobinopathies in australia. | to assess the infection risk of splenectomized persons with hemoglobinopathies in australia. | 2009 | 19136288 |
| invasive infection with hypermucoviscous klebsiella pneumoniae: multiple cases presenting to a single emergency department in the united states. | a distinctive form of community-acquired invasive klebsiella pneumoniae infection has been well described in southeast asia for more than 2 decades. the clinical syndrome includes liver abscess, bacteremia, and metastatic infection. it has recently been linked to a virulent hypermucoviscous k pneumoniae phenotype and to a specific genotype. as of 2008, there were only 2 published cases of invasive infection caused by this strain of k pneumoniae in the united states. we report 4 recent cases pres ... | 2009 | 19135282 |
| re-usable low density polyethylene arm glove for puerperal intrauterine exploration. | to design a long arm glove that can be used within a puerperal uterus to prevent the health-care worker contracting hiv from an infected patient. the designed long arm glove should be cheap (affordable) and readily available in low resource centres and must have proven sterility assurance and tensile strength to confer protection for the health worker. | 2008 | 19133425 |
| bacterial particle endocytosis by epithelial cells is selective and enhanced by tumor necrosis factor receptor ligands. | bacterial pathogens use virulence strategies to invade epithelial barriers, but active processes of epithelial cells may also contribute to the endocytosis of microbial particles. to focus on the latter, we studied the uptake of fixed and fluorescently labeled bacterial particles in intestinal and bronchoepithelial cell cultures and found it to be enhanced in caco-2bbe and nci-h292 cells after treatment with tumor necrosis factor alpha and an agonist antibody against the lymphotoxin beta recepto ... | 2009 | 19129472 |
| first report of ciprofloxacin resistance among klebsiella pneumoniae harbouring the qnra1 gene and producing shv-5 extended-spectrum beta-lactamase in scotland. | 2008 | 19129076 | |
| antimicrobial resistance among uropathogens responsible for community-acquired urinary tract infections in an italian community. | this study aimed to establish the pattern of the antimicrobial resistance among the leading uropathogens causing community-acquired utis in an area of the region of apulia, southern italy. twenty-one thousand and two hundred outpatients, 6,893 males and 14,307 females, were enrolled. urinary isolates were identified by conventional methods and the susceptibility to 18 antimicrobials determined. recognized uropathogens escherichia coli, klebsiella pneumoniae and proteus mirabilis were isolated fr ... | 2008 | 19129070 |
| klebsiella pneumoniae lo10 producing extended-spectrum beta-lactamase shv-12 in saudi arabia. | klebsiella pneumoniae lo10 was responsible for an outbreak that occurred in the neonatal unit at security forces hospital, kingdom of saudi arabia. over a period of eight months nine cases of bacteremia resulted in two deaths. resistance to third generation cephalosporins was transferred from strain lo10 to e. coli by both conjugation and transformation. sequence determination of the plasmid gene from two transconjugants and one transformant indicated that resistance was carried by a ca.100-kb p ... | 2008 | 19129068 |
| genetic diversity of genes encoding okp and len beta-lactamases produced by clinical klebsiella pneumoniae strains in portugal. | of the 308 clinical klebsiella pneumoniae strains collected in 21 portuguese health institutions, 11 encoded for len and 9 for okp enzymes; of these, 15 were new enzymes. ninety-one percent of len and all okp producer strains were resistant to amoxicillin. we demonstrate that these beta-lactamase were highly diverse. | 2009 | 19128913 |
| antifungal and antibacterial activities of mexican tarragon (tagetes lucida). | mexican tarragon (tagetes lucida cv. asteraceae: campanulatae) is an important, nutritious plant and an effective herbal medicine. seven coumarins, 7,8-dihydroxycoumarin (4), umbelliferone (7-hydroxycoumarin) (5), scoparone (6,7-dimethoxycoumarin) (7), esculetin (6,7-dihydroxycoumarin) (11), 6-hydroxy-7-methoxycoumarin (12), herniarin (7-methoxycoumarin) (13), and scopoletin (6-methoxy-7-hydroxycoumarin) (14), and three flavonoids, patuletin (18), quercetin (19), and quercetagetin (20), were iso ... | 2006 | 19127719 |
| occurrence and detection of ampc beta lactamases among clinical isolates of e. coli and k. pneumoniae causing uti. | presence of bush class c enzymes in uropathogenic strains of klebsiella pneumoniae & e. coli resistant to extended spectrum cephalosporins is an emerging threat to clinical therapeutics. these resistant strains result in considerable treatment failure and cannot be detected by routine antibiotic sensitivity screening methods. an effort was therefore made to study ampc beta lactamase production in e. coli and klebsiella pneumoniae strains causing uti. a total of 126 e. coli and 49 k. pneumnoniae ... | 2008 | 19127665 |
| interleukin-17 in host defence against bacterial, mycobacterial and fungal pathogens. | the mammalian immune system is intricately regulated, allowing for potent pathogen-specific immunity to be rapidly activated in response to infection with a broad and diverse array of potential pathogens. as a result of their ability to differentiate into distinct effector lineages, cd4 t cells significantly contribute to pathogen-specific adaptive immune responses. through the production of effector cytokines, cd4 t helper (th) cells orchestrate the precise mobilization of specific immune cells ... | 2009 | 19125888 |
| laboratory detection of extended-spectrum beta-lactamase by an automated system. | this study aims to evaluate the positive predictive value (ppv) and the negative predictive value (npv) of vitek2 in detecting extended-spectrum beta-lactamase (esbl) phenotypes when compared to a manual confirmatory test as gold standard. a sample of escherichia coli, klebsiella spp and proteus mirabilis isolates were collected by 5 laboratories in the emilia-romagna region (italy). vitek2 appears to be an accurate tool to detect esbl phenotypes of e. coli isolates; some concern remains about i ... | 2008 | 19123314 |
| orthokeratology associated microbial keratitis. | to report the clinical course, microbiologic findings, treatment, and outcomes of overnight orthokeratology associated microbial keratitis. | 2009 | 19123161 |
| microbial production of 2,3-butanediol from jerusalem artichoke tubers by klebsiella pneumoniae. | 2,3-butanediol is one of the promising bulk chemicals with wide applications. its fermentative production has attracted great interest due to the high end concentration. however, large-scale production of 2,3-butanediol requires low-cost substrate and efficient fermentation process. in the present study, 2,3-butanediol production by klebsiella pneumoniae from jerusalem artichoke tubers was successfully performed, and various technologies, including separate hydrolysis and fermentation (shf) and ... | 2009 | 19122999 |
| ctx-m type beta-lactamases among fecal escherichia coli and klebsiella pneumoniae isolates in non-hospitalized children and adults. | we investigated the occurrence and diversity of extended-spectrum beta-lactamase (esbl) enzymes among antibiotic-resistant escherichia coli and klebsiella pneumoniae isolates obtained from human feces. all esbl-positive isolates were characterized at the molecular level by polymerase chain reaction, sequencing and pulsed-field gel electrophoresis (pfge). eight of 46 antibiotic-resistant e. coli (6 from children and 2 from adults) and 4 of 8 k. pneumoniae (all from adults) isolates were found to ... | 2008 | 19122926 |
| topo-optical investigations on the surface of bacterial cells during the phagocytosis of klebsiella pneumoniae in mouse. | polarisation optical methods provide the means to perform sub-microscopic investigations on structures containing spatially highly ordered molecules, for example the cell envelope of prokaryotic cells. such structures can evoke birefringence, which can be enhanced or modified by different dyes or reagents, thus providing the possibility of a more specific investigation of the composition and structure of bacterial surface compounds. klebsiella pneumoniae synthesises sterically different carbohyd ... | 2009 | 19121536 |
| large scale multiplex pcr improves pathogen detection by dna microarrays. | medium density dna microchips that carry a collection of probes for a broad spectrum of pathogens, have the potential to be powerful tools for simultaneous species identification, detection of virulence factors and antimicrobial resistance determinants. however, their widespread use in microbiological diagnostics is limited by the problem of low pathogen numbers in clinical specimens revealing relatively low amounts of pathogen dna. | 2009 | 19121223 |
| antitumour and antimicrobial activities of endophytic streptomycetes from pharmaceutical plants in rainforest. | the aim of this study was to screen antitumour and antimicrobial activities of endophytic actinomycetes isolated from pharmaceutical plants in rainforest in yunnan province, china. | 2008 | 19120929 |
| subungueal pyogenic granuloma secondary to docetaxel therapy. | 2009 | 19120399 | |
| inhaled colistin as monotherapy for multidrug-resistant gram (-) nosocomial pneumonia: a case series. | reports of patients with polymyxin-only susceptible gram-negative nosocomial pneumonia treated with inhaled, but without concurrent intravenous, colistin are rare. | 2009 | 19118994 |
| protection of immuno-compromised mice from lethal infection of klebsiella pneumonia by raav2-bpi23-fcgamma1 gene transfer. | in previous research, chimerical bpi23-fcgamma1 gene which consisted of human bactericidal/permeability increasing protein (bpi) gene of encoding the functional n terminus (amino acid residues 1 to 199) of human bpi and fcgamma1 gene of encoding the fc segment of human immunoglobulin g1 was successfully reconstructed within a recombinant adeno-associated virus serotype 2 (raav2) vector as raav2-bpi23-fcgamma1. here, to evaluate the potentiality of applying gene therapy to gram negative bacterial ... | 2008 | 19118510 |
| intravenous colistimethate (colistin) use in critically ill children without cystic fibrosis. | the increasing frequency of infections caused by multidrug-resistant (mdr) gram-negative bacteria has led to the reappraisal of colistimethate use. | 2009 | 19116601 |
| xanthogranulomatous pyelonephritis successfully treated with antibiotics only. | a 73-year-old woman with leukemia presented with urinary tract infection, splenic abscess, and a renal mass. both urine culture and pus culture of the splenic abscess yielded klebsiella pneumoniae. percutaneous biopsy of the renal mass confirmed the diagnosis of xanthogranulomatous pyelonephritis. because of high risk for surgery, the patient received treatment with antibiotic therapy for 2 months. with antibiotic therapy, not only was the splenic abscess cured but follow-up ultrasonography also ... | 2008 | 19114330 |
| pyogenic liver abscess associated with septic pulmonary embolism. | 2008 | 19114323 | |
| biodegradation potential of pure and mixed bacterial cultures for removal of 4-nitroaniline from textile dye wastewater. | environmentally toxic aromatic amines including nitroanilines are commonly generated in dye contaminated wastewater in which azo dyes undergo degradation under anaerobic conditions. the aim of this study was to develop a process for biological treatment of 4-nitroaniline. three bacteria identified as acinetobacter sp., citrobacter freundii and klebsiella oxytoca were isolated from enrichment cultures of activated sludge on 4-nitroaniline, after which the isolates and the mixed culture were studi ... | 2009 | 19114284 |
| magnetic resonance imaging findings in a red kangaroo (macropus rufus) with otitis. | magnetic resonance imaging (mri) was performed on an adult, male red kangaroo (macropus rufus) with a history of nonspecific neurologic signs and acute discharge from the left ear. mri revealed findings consistent with otitis and possible osteomyelitis of the temporal and mastoid bones. to the authors' knowledge, this is the first report of otitis and mri findings in a kangaroo. | 2008 | 19110716 |
| a vim-1 metallo-beta-lactamase-producing klebsiella pneumoniae clinical isolate in an acute hospital in germany. | 2009 | 19108993 | |
| update on antimicrobial susceptibility rates among gram-negative and gram-positive organisms in the united states: results from the tigecycline evaluation and surveillance trial (test) 2005 to 2007. | the tigecycline evaluation and surveillance trial (ttest) is a global surveillance study initiated in 2004.its goal is to assess the in vitro activity of the glycylcycline, tigecycline, and comparator antimicrobials. objective: the aim of this study was to measure the in vitro activity of a panel of antimicrobial agents against gram-negative and gram-positive organisms collected in the united states in 2005, 2006, and 2007. | 2008 | 19108792 |
| use of the iso 9308-1 procedure for the detection of e. coil in water utilizing two incubation temperatures and two confirmation procedures and comparison with defined substrate technology. | disinfected and non-disinfected samples have been used to determine the accuracy of the iso procedure (iso 9308-1) for detection of e. coli in drinking water. samples were analysed using the iso procedure at both 36 and 44 degrees c and using the defined substrate technology method colilert-18/quanti-tray (colilert-18). utilizing the confirmation procedure described in iso 9308-1, large numbers of false positive e. coli results were obtained using the iso primary isolation procedure at 36 degree ... | 2008 | 19108560 |
| the action of barbitone on aerobacter aerogenes (klebsiella aerogenes). | 1967 | 19108244 | |
| microarray of dna-protein complexes on poly-3-hydroxybutyrate surface for pathogen detection. | a novel strategy was developed for the specific immobilization of dna probes on poly-3-hydroxybutyrate (phb) surface by using the substrate-binding domain (sbd) of phb depolymerase as an active binding motif. to demonstrate whether this method can be used for the detection of clinical pathogens, the pathogen-specific biotin-labeled dna probes were immobilized via core streptavidin (csa) fused to the sbd. the pathogen-specific 15-mer oligonucleotide probes were designed for four model pathogens, ... | 2009 | 19107467 |
| antimicrobial resistance among neonatal pathogens in developing countries. | knowledge of antimicrobial resistance and trends in resistance patterns among major pathogens causing infections in young infants (up to 90 days of life) is an important component of developing community-based management strategies. hospital-based data suggest alarming rates of resistance to ampicillin and gentamicin, the first-line antimicrobial agents recommended by who for treatment of serious infections in young infants. | 2009 | 19106758 |
| pathogens associated with sepsis in newborns and young infants in developing countries. | knowledge of pathogens causing infections in young infants (up to 90 days of life) is essential for devising community-based management strategies. most etiological data from developing countries are hospital-based and may have little relevance to communities in which most babies are born at home. | 2009 | 19106757 |
| cmy-31 and cmy-36 cephalosporinases encoded by cole1-like plasmids. | two cmy-2 derivatives, cmy-31 (gln(215)-->arg) from salmonella enterica serotype newport and cmy-36 (ala(77)-->cys and gln(193)-->glu) from klebsiella pneumoniae, were characterized. both cephalosporinases functionally resembled cmy-2. bla(cmy) alleles occurred as parts of a putative transposon comprising isecp1b and a citrobacter freundii-derived sequence carried by cole1-like plasmids similar to cmy-5-encoding ptkh11 from klebsiella oxytoca. | 2009 | 19104021 |
| klebsiella pneumoniae: caught on film. | 2009 | 19103780 | |
| massive necrotizing pneumonia with pulmonary gangrene. | pulmonary gangrene is an extremely rare and severe complication of pneumonia. it is very rarely seen in community-acquired pneumonia. a 49-year-old immunocompetent man was admitted with community-acquired pneumonia caused by klebsiella pneumonia. his condition rapidly deteriorated with ensuing pulmonary gangrene and septic shock. he was successfully managed by emergency pneumonectomy. | 2009 | 19101324 |
| introduction of an nadh regeneration system into klebsiella oxytoca leads to an enhanced oxidative and reductive metabolism of glycerol. | redox cofactors play crucial roles in the metabolic and regulatory network of living organisms. we reported here the effect of introducing a heterogeneous nadh regeneration system into klebsiella oxytoca on cell growth and glycerol metabolism. expression of fdh gene from candida boidinii in k. oxytoca resulted in higher intracellular concentrations of both nadh and nad(+) during the fermentation metaphase, with the ratio of nadh to nad(+) unaltered and cell growth unaffected, interestingly diffe ... | 2009 | 19100856 |
| klebsiella pneumoniae mrkd adhesin-mediated immunity to respiratory infection and mapping the antigenic epitope by phage display library. | in this study, the k. pneumoniae mrkd adhesin was identified an immunodominant antigen which correlated with protection against infection by k. pneumoniae. the mouse monoclonal antibodies (mabs) against mrkd adhesin were produced by the hybridoma technique using recombinant mrkd-gst as the immunogen and were immunoscreened against phage-displayed random dodecapeptide library (ph.d.-12). after three rounds of biopanning, 36 phage clones were randomly selected and their specificity to mab was veri ... | 2009 | 19100827 |
| [bacterial etiology of pneumonia in hospitalized children: combined detection with culture and polymerase chain reaction]. | bacterial cultures from respiratory aspirate or sputum have been the conventional diagnostic method for pneumonia, but the results of culture was often affected by early extensive use of antibiotics, sample collection and delivery. the objective of this study was to explore application of the combined detection of culture and polymerase chain reaction (pcr) assay in hospitalized children with pneumonia. | 2008 | 19099875 |
| [comparative analysis of the pathogens responsible for hospital acquired and community acquired late onset neonatal septicemia]. | late onset neonatal septicemia (systemic infection after 72 hours of life) remains a major cause of neonatal morbidity and mortality. early treatment with appropriate antibiotics is critical since infected infants can deteriorate rapidly. the aim of this study was to review the pathogens responsible for late onset neonatal septicemia (lons) and their antimicrobial susceptibilities in order to guide the initial selection of appropriate antibiotics for infants with suspected lons. | 2008 | 19099687 |
| extended-spectrum beta-lactamase-producing klebsiella pneumoniae in a neonatal intensive care unit in león, nicaragua. | 2009 | 19097869 | |
| predominance of ctx-m-15 extended spectrum beta-lactamases in diverse escherichia coli and klebsiella pneumoniae from hospital and community patients in kuwait. | 2009 | 19097760 | |
| ertapenem peritoneal fluid concentrations in adult surgical patients. | ertapenem, a novel carbapenem, is approved for the treatment of mild to severe intra-abdominal infections (iais), although its in vivo concentrations in peritoneal fluid are unknown. the purpose of this study was to determine the peritoneal fluid concentration of ertapenem after a single 1 g intravenous dose. after informed consent, 21 patients (9 females and 12 males; mean+/-standard deviation (s.d.) age 50.2+/-17.7 years) requiring intra-abdominal surgery were enrolled. plasma and peritoneal f ... | 2009 | 19097758 |
| metallo-beta-lactamases in gram-negative bacteria: introducing the era of pan-resistance? | metallo-beta-lactamases (mbls) are being reported with increasing frequency and from several countries worldwide and are becoming the prevalent and most clinically significant determinants of carbapenem resistance. furthermore, mbl-producing strains that exhibit a pan-resistant phenotype are increasingly detected. initially mbls were detected in pseudomonas aeruginosa, however nowadays they are frequently found in acinetobacter baumannii, klebsiella pneumoniae and other enterobacteriaceae. mbls ... | 2009 | 19095416 |
| a case of infliximab-induced psoriasis. | anti-tumor necrosis factor (anti-tnf-alpha) are a group of new drugs able to inhibit the action of this cytokine. although systemic side effects have been well described, cutaneous adverse reactions have not yet been clearly elucidated. the authors report a case of a 29-year-old man affected by crohn disease and ankylosing spondylitis who developed psoriatic lesions after iv infusion of infliximab 5 mg/kg. the patient underwent cyclosporine treatment after interruption of biological therapy, and ... | 2008 | 19094847 |
| systemic dexamethasone and its effect on normal aerobic bacterial flora of cow. | this study was carried out on 17 holestein, heifers, aged between 1 to 2 years for determining the normal aerobic bacterial flora and their changes after dexamethasone injection. swab samples were taken from eye, ear, pharynx and vagina before and 5 days after twice dexamethasone treatment. results indicated that bacillus cereus and corynebacterium pseudotuberculosis had higher frequency of isolations than the other bacterial flora in eye, ear and pharynx. actinomyces pyogenes was isolated with ... | 2007 | 19093453 |
| comparative pharmacodynamics for intravenous antibiotics against gram-negative bacteria in europe between 2002 and 2006: a report from the optama program. | the optimizing pharmacodynamic target attainment using the mystic antibiogram (optama) program has been used globally to estimate antimicrobial exposures for either targeted pathogens or disease states. herein, we utilised this methodology to determine antimicrobial exposures of cefepime, ceftazidime, ciprofloxacin, imipenem, meropenem and piperacillin/tazobactam against european-derived isolates of escherichia coli, klebsiella pneumoniae, acinetobacter baumannii and pseudomonas aeruginosa obtai ... | 2009 | 19091515 |
| [severe laryngotracheal involvement in a case of rhinoscleroma due to klebsiella pneumoniae subspecies ozaenae]. | 2008 | 19091241 | |
| dissemination of extended-spectrum beta-lactamase-producing klebsiella pneumoniae and escherichia coli in thai hospitals. | fifty clinical isolates of klebsiella pneumoniae and escherichia coli with reduced susceptibility to third-generation cephalosporins, collected from 11 hospitals in thailand, were studied. all isolates were found to produce extended-spectrum beta-lactamase (esbl), as judged by double-disk synergy and combination disk methods. most esbl-producing k. pneumoniae isolates were resistant to ceftazidime (94%) and aztreonam (90%). in contrast, most esbl-producing e. coli isolates were resistant to ceft ... | 2008 | 19089552 |
| liver abscess in neonates. | liver abscesses are rare in neonates with the majority resulting from an ascending infection via the umbilical and portal veins, haematogenous spread, or via the biliary tree, or via direct contiguous spread from neighbouring structures. they may present in unusual ways often presenting with ongoing sepsis and resulting in diagnostic difficulties. we present the clinical and radiological findings on six neonates with hepatic abscesses and underline the association with misplacement of umbilical ... | 2009 | 19089433 |
| epidemiology of bloodstream infection associated with parenteral nutrition. | epidemiology: catheter-related bloodstream infections (cr-bsis) occur in 1.3% to 26.2% of patients with central venous catheters used to administer parenteral nutrition (pn). because of their nutritional components, pn solutions can support microbial growth. contamination during preparation and handling is rare in hospitals and home-infusion pharmacies but may be difficult to control in a home setting. the risk of infection is increased in hospitalized patients because of malnutrition-associated ... | 2008 | 19084152 |
| [risk factors and prognosis in 31 patients with extended-spectrum beta-lactamase producing escherichia coli and klebsiella pneumoniae bloodstream infection]. | to investigate the risk factors, prognosis and resistance to antibiotics in patients with extended-spectrum b-lactamase (esbls)-producing escherichia coli and klebsiella pneumoniae bloodstream infection. | 2008 | 19080534 |
| [pathogens and drug resistance of pulmonary infection in aids patients]. | to study the pathogens and drug resistance profiles of pulmonary infection in patients with aids. | 2008 | 19080136 |
| a fatty acid messenger is responsible for inducing dispersion in microbial biofilms. | it is well established that in nature, bacteria are found primarily as residents of surface-associated communities called biofilms. these structures form in a sequential process initiated by attachment of cells to a surface, followed by the formation of matrix-enmeshed microcolonies, and culminating in dispersion of the bacteria from the mature biofilm. in the present study, we have demonstrated that, during growth, pseudomonas aeruginosa produces an organic compound we have identified as cis-2- ... | 2009 | 19074399 |
| evaluation of boronic acid disk tests for differentiating kpc-possessing klebsiella pneumoniae isolates in the clinical laboratory. | the worldwide increase in the occurrence and dissemination of kpc beta-lactamases among gram-negative pathogens makes critical the early detection of these enzymes. boronic acid disk tests using different antibiotic substrates were evaluated for detection of kpc-possessing klebsiella pneumoniae isolates. a total of 57 genotypically confirmed kpc-possessing k. pneumoniae isolates with varying carbapenem mics were examined. to measure the specificity of the tests, 106 non-kpc-possessing isolates ( ... | 2009 | 19073868 |
| microbiology of gallbladder bile in uncomplicated symptomatic cholelithiasis. | few studies have assessed microflora and their antibiotic sensitivity in normal bile and lithogenic bile with different types of gallstones. | 2008 | 19073410 |
| spread of ctx-m-type extended-spectrum beta-lactamases among bloodstream isolates of escherichia coli and klebsiella pneumoniae from a korean hospital. | this study was to determine the prevalence and characteristics of ctx-m-type extended-spectrum beta-lactamases (esbls) in nonduplicate escherichia coli (n=760) and klebsiella pneumoniae (n=379) bloodstream isolates collected during january 2005 to october 2007 at a university hospital (2000 beds) in seoul, korea. antimicrobial susceptibilities were determined by disk diffusion and agar dilution methods. the double-disk synergy test detected esbls in 8.7% (66/760) of e. coli and 11.3% (43/379) of ... | 2009 | 19073302 |
| prevalence of bacteria and intestinal parasites among food-handlers in gondar town, northwest ethiopia. | food-handlers with poor personal hygiene working in food-service establishments could be potential sources of infection due to pathogenic organisms. the study was undertaken to determine the prevalence of bacteria and intestinal parasites among 127 food-handlers working in the cafeterias of the university of gondar and the gondar teachers training college, gondar, ethiopia. fingernail contents of both the hands and stool specimens were collected from all the 127 food-handlers. the samples were e ... | 2008 | 19069624 |
| antimicrobial resistance of bacterial agents of the upper respiratory tract of school children in buea, cameroon. | the study was aimed at determining bacterial agents of the upper respiratory tract and the susceptibility patterns of isolates to antibiotics. in total, 200 throat swabs were obtained from students attending different boarding schools within the buea municipality and screened to obtain the prevalence of respiratory pathogens and to understand the antibiotic susceptibility patterns of isolates using standard microbiological procedure and the disc-diffusion test. of the 200 samples screened, 112 ( ... | 2008 | 19069618 |
| major enzymatic factors involved in bacterial penicillin resistance in burkina faso. | many clinical species of bacteria were isolated from biological samples such as urines, blood and wound in saint camille medical centre of ouagadougou. among the concerned species, the most important members were escherichia coli and klebsiella pneumoniae. these p-lactamases producing isolates were directly screened by pcr to identify the nature of the amplified genes responsible for penicillin destroying activity. therefore specific tem and shv primers were used. the pcr products were sequenced ... | 2007 | 19069526 |
| antibacterial activity of the broad bean extracts on resistant bacteria. | the antimicrobial activities of four different extracts (ethanol, methanol, distilled water and 2-methylbutan-1-01) obtained from different parts of broad bean (vicia faba l.) such as flowers, leaves, seeds and seed hulls and were tested against bacillus subtilis, serratia marcescens, staphylococcus aureus, escherichia coli, klebsiella peneumoniua, shigella sp. and micrococcus pyogenes. better antimicrobial activity was observed with the leaves of broad bean sterile distilled water extract with ... | 2007 | 19069508 |
| [detection of ampc beta-lactamases in gram-negative bacteria isolated from urine]. | ampc beta-lactamases, enzymes produced by a range of gram-negative bacteria and able to hydrolyse penicillins, monobactams, cephalosporins and cephamycins, are not inhibited by beta-lactamase inhibitors. they are spread via plasmids and pose a huge epidemiological and diagnostic problem. the production of ampc b-lactamases was tested in various gram-negative bacteria. of strains isolated from urine of patients diagnosed with urinary tract infection, we selected those that were resistant to third ... | 2008 | 19069027 |
| changing trend in antimicrobial resistance of pediatric uropathogens in taiwan. | there is growing concern regarding antimicrobial resistance worldwide, particularly of escherichia coli, and the first choice of an antimicrobial agent for empiric treatment of pediatric urinary tract infection (uti) is not well established. | 2008 | 19067894 |
| potent ligands for prokaryotic udp-galactopyranose mutase that exploit an enzyme subsite. | udp-galactopyranose mutase (ugm or glf), which catalyzes the interconversion of udp-galactopyranose and udp-galactofuranose, is implicated in the viability and virulence of multiple pathogenic microorganisms. here we report the synthesis of high-affinity ligands for ugm homologues from klebsiella pneumoniae and mycobacterium tuberculosis. the potency of these compounds stems from their ability to access both the substrate binding pocket and an adjacent site. | 2009 | 19067595 |
| postantibiotic effect of tigecycline against 14 gram-positive organisms. | the in vitro postantibiotic effects (paes), postantibiotic sub-mic effects (pa-smes), and sub-mic effects of tigecycline were determined for 14 gram-positive and gram-negative organisms. the pneumococcal, staphylococcal, and enterococcal paes were 1.9 to 5.1, 2.9 to 5.7, and 3.9 to 6.1 h, respectively, and those for haemophilus influenzae, escherichia coli, klebsiella pneumoniae, enterobacter cloacae, and acinetobacter baumannii were 1.1 to 5.0, 1.9 to 2.1, 1.7 to 1.8, 1.0 to 1.7, and 0.7 to 3 h ... | 2009 | 19064899 |
| prevalence of plasmid-mediated quinolone resistance determinants over a 9-year period. | recently, several plasmid-mediated quinolone resistance (pmqr) genes conferring low levels of quinolone resistance have been discovered. to evaluate the temporal change in the prevalence of pmqr genes over a decade in a tertiary hospital in the republic of korea, we selected every fifth isolate of escherichia coli and klebsiella pneumoniae and every third isolate of enterobacter cloacae between 1998 and 2001 and between 2005 and 2006 from a collection of blood isolates. six pmqr genes [qnra, qnr ... | 2009 | 19064896 |
| fullerene derivatized s-triazine analogues as antimicrobial agents. | a series of novel fullerene derivatives bearing s-triazine moiety have been synthesized by adopting 1,3 dipolar cycloaddition reaction of c(60) and azomethine ylides generated from the corresponding schiff bases of 2,4,6 trisubstituted s-triazine. all the compounds synthesized were characterized by elemental analysis, ft-ir, (1)h nmr, (13)c nmr and fab-ms. the compounds were then screened for their antibacterial activity against both gram-positive (staphylococcus aureus, bacillus subtilis, bacil ... | 2009 | 19062138 |
| study on the bacterial midgut microbiota associated to different brazilian populations of lutzomyia longipalpis (lutz & neiva) (diptera: psychodidae). | the bacterial community associated with the midgut of three brazilian lutzomyia longipalpis (lutz & neiva) populations, two from endemic areas for visceral leishmaniasis (jacobina, bahia state and são luís, maranhão state) and one from a non-endemic area (lapinha cave, minas gerais state), was identified. five groups, 35 females each, from each population were separated; a total of 175 females per collecting area were analyzed. the species identification was based on molecular and traditional ba ... | 2008 | 19061048 |
| are topical antimicrobials effective against bacteria that are highly resistant to systemic antibiotics? | an increasing number of bacteria are resistant to multiple systemic antibiotics. the purpose of this study was to determine if topical antimicrobials are still effective against multi-drug resistant organisms (mdros). mdros, including acinetobacter, pseudomonas, klebsiella, staphylococcus, and enterococcus, were collected from four burn hospitals. the sensitivity of 47 mdros to 11 commonly used topical agents (mafenide acetate, nystatin, mafenide + nystatin, silver nitrate, dakin's, polymyxin b, ... | 2009 | 19060725 |
| purine utilization by klebsiella oxytoca m5al: genes for ring-oxidizing and -opening enzymes. | the enterobacterium klebsiella oxytoca uses a variety of inorganic and organic nitrogen sources, including purines, nitrogen-rich compounds that are widespread in the biosphere. we have identified a 23-gene cluster that encodes the enzymes for utilizing purines as the sole nitrogen source. growth and complementation tests with insertion mutants, combined with sequence comparisons, reveal functions for the products of these genes. here, we report our characterization of 12 genes, one encoding gua ... | 2009 | 19060149 |
| hospital-acquired infection surveillance in a neonatal intensive care unit. | hospital-acquired infections (hais) represent an important cause of morbidity and mortality in neonatal intensive care units (nicus). | 2009 | 19059676 |
| etiology of neonatal blood stream infections in tbilisi, republic of georgia. | neonatal blood stream infections (bsi) are a major cause of morbidity and mortality in developing countries. it is crucial to continuously monitor the local epidemiology of neonatal bsi to detect any changes in patterns of infection and susceptibility to various antibiotics. | 2009 | 19058989 |
| antimicrobial susceptibility of udder pathogens from cases of acute clinical mastitis in dairy cows. | to investigate occurrence of acquired antimicrobial resistance in udder pathogens mics in staphylococcus aureus (n=211), coagulase-negative staphylococci (cns) (n=56), streptococcus uberis (n=113), streptococcus dysgalactiae (n=152), streptococcus agalactiae (n=6), escherichia coli (n=163), and klebsiella spp. (n=42) were determined using microdilution. isolates were from a nation wide survey employing strict inclusion criteria. presence of acquired resistance was evaluated by species-specific e ... | 2009 | 19058930 |
| antibiotic-resistant bacteria and infection in children with cerebral palsy requiring mechanical ventilation. | severe and chronic illness can alter the bacterial flora carried in the oropharynx and gut. there are little data on the bacterial flora of children with chronic neurologic impairment. | 2009 | 19057452 |
| first characterization and emergence of shv-60 in raw milk of a healthy cow in japan. | during monitoring of raw milk samples from healthy cows for the presence of antibiotic resistant bacteria, one isolate of klebsiella pneumoniae strain huf-100 was found to be resistant to oxyimino-cephalosporins and aztreonam. it was found to carry a chromosomally-encoded extended-spectrum beta-lactamase that has not been described previously, namely shv-60. thus, it must be expected that this strain will spread further among food-producing animals and thereby constitute a reservoir of this resi ... | 2008 | 19057150 |