Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
|---|
| [research on antibodies against bhv-1, bhv-2, bhv-4, bvd-md virus, bovine adenovirus a and b, rotavirus and coronavirus in cattle in western zaire: complementary results]. | two-hundred bovine sera from western zaire were screened for antibodies to 8 viruses: bhv-1, bhv-2, bhv-4, bvd-md virus, bovine adenovirus a and b, bovine rotavirus and bovine coronavirus. positive sera were found to all these viruses. for animals whose origin was undoubted, the main features were the high prevalence of infections by rotavirus and bhv-4 and the low prevalence of infections by coronavirus and bvd-md virus. | 1989 | 2560579 |
| prevalence of bovid herpesvirus-4 and its antibody in cattle in minnesota. | serologic analyses and virus isolation studies were carried out to determine the role of bovid herpesvirus-4 (bhv-4) in infections in cattle, principally those of the reproductive tract. serologic analyses were performed, using an indirect fluorescent antibody test on thoracic fluid specimens from aborted fetuses and on sera from 3 sources of adult cattle. virus isolation was attempted from field cases of abortion, early embryo death, and postpartum vulvovaginitis/metritis, using uterine dischar ... | 1989 | 2559632 |
| experimental infection of bulls with a genital isolate of bovine herpesvirus-4 and reactivation of latent virus with dexamethasone. | five 13- to 18-month old belgian blue bulls were used in this experiment. four bulls (nos. 2, 3, 4 and 5) were inoculated intratesticularly with 10(5) plaque-forming units of bovine herpesvirus-4 (bhv-4) in each testicle (day 0). the challenge bhv-4 strain was previously isolated from testicle cells of a bull exhibiting orchitis and azoospermia. the fifth bull (no. 1) was used as a control and received the same volume of uninfected cell culture supernatant. for 5 days, beginning on day 51 post-i ... | 1989 | 2558442 |
| bovine encephalitis herpesvirus. | 1989 | 2557703 | |
| a bovine herpesvirus (bhv-4) as passenger virus in ethmoidal tumours in indian cattle. | a herpesvirus was isolated from tumours of the ethmoidal mucosa in two of three head of cattle in the state of kerala, india. the virus designated m40 was cytopathic for a variety of cultured bovine and porcine cells and it did not kill suckling mice or chicken embryos. sera from tumour-bearing cattle and goats reacted with the m40 virus. immunofluorescence tests with fitc-conjugated igg from a bovine monospecific antiserum to bovine herpesvirus 4 (bhv-4) stained the m40 virus specific antigen i ... | 1989 | 2554622 |
| [serologic and virologic studies of selected cattle with antibodies to bovine herpesviruses]. | in order to investigate the specificity of low titer antibodies to bhv 1, twelve cattle were subjected to stress and dexamethasone treatment. they were monitored virologically by inoculating cell cultures with naso-pharyngeal-, ocular- and vaginal- or preputial swabs and serologically by assessing the prevalence and incidence of antibodies to bovine, caprine-, porcine-, and equine herpesviruses and to bovine leukemia virus. antibodies were classified as specific for bhv 1 if the animals excreted ... | 1989 | 2544992 |
| clinicopathologic and pathologic findings of herpesvirus-induced urinary tract infection in conventionally reared cats. | clinicopathologic manifestations of induced infection of the feline lower urinary tract with bovid herpesvirus-4 (bhv-4, strain fcahv) were characterized in 6 conventionally reared adult cats (2 sexually intact males, 2 castrated males, and 2 females). two additional control cats were exposed with noninfected cell culture control inoculum. clinical and radiographic signs of lower urinary tract disease were not observed in exposed or control cats. microscopic hematuria was detected in urine sampl ... | 1990 | 2173448 |
| a serological comparison of some animal herpesviruses. | bovine herpesvirus 1 (bhv-1) isolates (cooper-type strain 4975 and oxford) were compared in neutralization tests with the bovine herpesvirus 4 (bhv-4) isolate (85/16 tv) and the herpesviruses of red deer (d2839/1) and goats (e/ch). hyperimmune antiserum was prepared in rabbits against the plaque-selected viruses and endpoint and kinetic neutralization test were made. bhv-4 was clearly different from the other four viruses. the closely-related bhv-1 strains were also related in these tests to the ... | 1990 | 2170074 |
| comparative genome mapping of bovine encephalitis herpesvirus, bovine herpesvirus 1, and buffalo herpesvirus. | a clone library of 11 of 15 bamhi fragments representing 81% of the 140 kilobase dna genome of the prototype bovine encephalitis herpesvirus strain n569 (behv.n569) was constructed. the clones were used to verify the bamhi, bsteii, ecori, and hindiii genomic maps for behv.n569 published by engels et al. [virus res 6: 57-73 (1986)] for the same virus although some amendments/variations to the bamhi map were found in that 3 previously unidentified restriction sites were identified. restriction sit ... | 1990 | 2167057 |
| clinicopathologic analysis of herpesvirus-induced urinary tract infection in specific-pathogen-free cats given methylprednisolone. | the clinicopathologic manifestations of bovid herpesvirus-4 (bhv-4; fcahv strain)-induced infection of the lower portion of the urinary tract were characterized in 12 adult neutered male and 6 female specific-pathogen-free cats, and were compared with those in 12 neutered male control cats. six neutered male and 6 female cats were given immunosuppressive doses of methylprednisolone acetate prior to inoculation of their urinary bladders with bhv-4. six neutered male control cats were given immuno ... | 1990 | 2164332 |
| evaluation of pregnant rabbits as a laboratory model for bovid herpesvirus-4 infection. | a field strain (87-8363) of bovid herpesvirus-4 (bhv-4) isolated from an aborted bovine fetus was used to inoculate pregnant rabbits. eleven rabbits in midgestation were alloted to 4 groups consisting of 3 infected groups and 1 control group. rabbits were inoculated with bhv-4 or mock-infected cell culture preparations via iv, intravaginal, and intrauterine routes. mild vulvovaginitis and endometritis were observed after intravaginal and iv inoculation of bhv-4, whereas intrauterine inoculation ... | 1990 | 2158255 |
| the biology of bovine herpesvirus-4 infection of cattle. | the biology of bovine herpesvirus-4 (bhv-4) infection of cattle is reviewed. the infection is distributed worldwide. most of isolated viruses are non-pathogenic in cattle; some of them are able to produce a genital disease. twenty-nine structural polypeptides were described; ten of them are glycosylated. two major glycoproteins were characterized by monoclonal antibodies. restriction maps of bhv-4 dna are available for the enzymes ecori, bamhi and hindiii. the strain variations studied by restri ... | 1990 | 2155770 |
| serological evidence of herpesvirus infection in captive asian elephants (elephas maximus). | in mid 1988 a 3-yr-old asian elephant (elephas maximus) from a circus in switzerland died following generalized manifestation of a herpesvirus infection. in an effort to determine prevalence of infection with the herpesvirus, and due to lack of a corresponding virus isolate, it was decided to evaluate contact animals and elephants from a second herd for antibody to bovine herpesvirus 1 (bhv1) and bovine herpesvirus 2 (bhv2). of 15 sera tested four displayed low neutralizing antibody titers to bh ... | 1990 | 2154628 |
| bovine encephalitis herpesvirus. | 1990 | 2154072 | |
| [the etiology of "malignant catarrhal fever" originating in sheep: serological findings in cattle and sheep with ruminant gamma herpesviruses]. | in the case of the wildebeest-derived form of malignant catarrhal fever (wd-mcf) alcelaphine herpesvirus 1 (alchv1) is well established as the cause. however, the etiology of the form of the disease circumstantially associated with sheep (sa-mcf) remains equivocal. a serological relationship has been proposed to exist between the unidentified sheep-associated agent causing sa-mcf and alchv1 causing wd-mcf. we attempted to confirm this hypothesis. using an indirect elisa we found 94 of 100 cattle ... | 1991 | 2068708 |
| the isolation of lumpy skin disease virus and bovine herpesvirus-4 from cattle in egypt. | lumpy skin disease (lsd) virus (lsdv) was isolated for the first time from cattle in egypt in 2 disease outbreaks. bovine herpesvirus-4 (bhv-4) and lsdv were detected in a pooled sample from the first outbreak (suez). only lsdv was isolated from the second outbreak (ismalia). the capripoxviruses were identified as lsdv by neutralization with specific antiserum and by their ability to produce generalized lsd in experimentally inoculated cattle. | 1990 | 1965577 |
| a dot immunobinding assay on nitrocellulose for the detection of bovid herpesvirus-4 antibodies. | a dot immunobinding assay (dia) was developed for the detection of antibody against bovid herpesvirus-4 (bhv-4) in bovine sera. a semipurified virus preparation was used as the antigen and an antispecies horseradish peroxidase-labeled igg and diaminobenzidine were employed as the detection system. the sensitivity and specificity of the dia were similar to those of indirect fluorescent antibody test, indicating the suitability of dia as a rapid field test for the detection of anti-bhv-4 antibodie ... | 1990 | 1965576 |
| molecular diagnosis of alcelaphine herpesvirus (malignant catarrhal fever) infections by nested amplification of viral dna in bovine blood buffy coat specimens. | a fragment of alcelaphine herpesvirus-1 (ahv-1; malignant catarrhal fever) dna was subcloned into puc 18 and sequenced. the subclone hybridized strongly to ahv-1 dna, weakly to alcelaphine herpesvirus-2 (ahv-2) dna, and not at all to dna from bovine herpesvirus-1 (bhv-1; infectious bovine rhinotracheitis [ibr] virus), bovine herpesvirus-2 (bhv-2; bovine herpes mamillitis [bhm] virus), and bovine herpesvirus-4 (bhv-4; isolate dn599). a 2-stage (nested) polymerase chain reaction (pcr) diagnostic t ... | 1991 | 1911989 |
| characterization of the bovine herpesvirus 4 major immediate-early transcript. | the major immediate-early (ie) rna of bovine herpesvirus 4 (bhv-4) has been identified and characterized by analyzing cytoplasmic polyadenylated rna isolated from madin-darby bovine kidney cells infected with bhv-4(dn-599) in the presence of cycloheximide. hybridization of cdna to southern blots of viral dna, northern (rna) blot analysis, and s1 nuclease analyses showed that the major bhv-4 ie rna is a spliced, 1.7-kb rna, which is transcribed from right to left on the restriction map of the bhv ... | 1991 | 1716688 |
| antigenic and genomic identity between simian herpesvirus aotus type 2 and bovine herpesvirus type 4. | herpesvirus aotus type 2 (hva-2) was isolated from a culture of kidney cells from a healthy owl monkey (aotus trivirgatus). bovine herpesvirus type 4 (bhv-4) is frequently isolated from diseased and even healthy cattle and occasionally from sheep, wild ruminants and cats. the two viruses are related antigenically, as was revealed by an indirect fluorescent antibody test using polyclonal antisera from experimentally infected rabbits or monoclonal antibodies raised against six bhv-4 proteins, thre ... | 1991 | 1706410 |
| nucleotide and amino acid sequence analysis of the thymidine kinase gene of a bovine encephalitis herpesvirus. | the nucleotide and predicted amino acid sequence of the thymidine kinase (tk) gene of n 569, a bovine encephalitis herpesvirus (behv), has been determined and compared with those of avian, bovine and other mammalian herpesvirus tk genes. striking differences were observed between the nucleotide sequence of this behv tk gene and those reported for bovine herpesvirus 1 (bhv-1). a total of 118 base changes, 39 base deletions and 14 base insertions were identified relative to the tk sequence of a bh ... | 1991 | 1678935 |
| a study of some biologic properties of bovid herpesvirus-4. | this article summarizes the results of a study on several strains of bovid herpesvirus-4 (bhv-4), isolated from cattle. the study had several objectives, namely, to verify (a) the disease-causing potential of the virus, (b) the possibility by bhv-4 to induce a latent infection in the natural host and (c) the entity of the relationships among strains of the virus isolated from different disease syndromes. the following data were obtained: (1) all strains tested were able to replicate in experimen ... | 1991 | 1657513 |
| biological and molecular aspects of bovine herpesvirus 4 (bhv-4). | this review summarizes most recent information on the bovine cytomegalovirus bhv-4. the virus is not associated with clearly defined clinical entities in cattle. it can easily be isolated in tissue culture and has a broad host range. bhv-4 strains are rather similar in restriction enzyme analysis of their dnas, the size of the pr dnas, however, differs. the genome represents a gamma-herpesvirus. because of its uniqueness bhv-4 is discussed as an appropriate vector. | 1991 | 1657512 |
| clinical evaluation of cats with lower urinary tract disease. | in a prospective study, 141 cats with hematuria, dysuria, urethral obstruction, or combinations of these signs were evaluated by contemporary diagnostic methods and compared with 26 clinically normal cats (controls). specific diagnosis was established in 45% (64/141) of cats affected with lower urinary tract disease (lutd). crystalline matrix plug-induced urethral obstruction was diagnosed in 21% (30/141) of affected cats, uroliths were identified in 21% (30/141) of affected cats, uroliths with ... | 1991 | 1653776 |
| tissue distribution of bovid herpesvirus-4 in inoculated rabbits and its detection by dna hybridization and polymerase chain reaction. | a dna hybridization technique, using the polyrepetitive ecori l-fragment of bovid herpesvirus (bhv-4) as a probe, was developed to determine virus distribution in the tissues of bhv-4-infected pregnant rabbits. the cloned fragment did not react with the dna of rabbits or of other herpesviruses, e.g., infectious bovine rhinotracheitis, bovine herpes virus mammillitis, and pseudorabies viruses. the detection limit was 10(-13) g of dna or approximately 600 genome equivalents of viral dna, which ind ... | 1991 | 1652236 |
| [significance of bovine herpesvirus 4 and its detection]. | in the last years different strains of the bovine cytomegalo-virus have been isolated. they have been grouped as bovine herpes virus 4 (bhv 4) and separated from other bovine herpes viruses. their clinical importance remains uncertain. different tests to detect infection have been developed. | 1991 | 1648799 |
| variation in the pathogenic potential and molecular characteristics of bovid herpesvirus-4 isolates. | seven bovid herpesvirus-4 (bhv-4) isolates recovered from various clinical conditions of cattle were studied for their pathogenic potential in pregnant rabbits. these viruses were originally recovered from respiratory and reproductive tract infections of cattle. a virus dose of 4 x 10(6.8)tcid50 per fetus was inoculated via the intrauterine route in 10- and 17-day pregnant rabbits. clinical, virologic, and pathologic data were collected to compare the effect of each isolate on does and fetuses/k ... | 1991 | 1646514 |
| molecular biology of bovine herpesvirus type 4. | bovine herpesvirus type 4 (bhv-4) is a ubiquitous virus of cattle. its genome is a 144 +/- 6 kb double-stranded dna consisting of a unique central part (l-dna) flanked at both ends by tandem repeats called polyrepetitive dna (prdna or h-dna). the overall arrangement of genes has been obtained by the analysis of homologies between short bhv-4 dna sequences and corresponding genes of epstein-barr virus (ebv) and herpesvirus saimiri (hvs). the gene expression is temporally regulated. glycoprotein p ... | 1992 | 1336253 |
| effects in calves of mixed infections with bovine viral diarrhea virus and several other bovine viruses. | the objective of this study was to verify whether a mixed infection in calves with bovine viral diarrhea virus (bvdv) and other bovine viruses, such as bovid herpesvirus-4 (bhv-4), parainfluenza-3 (pi-3) and infectious bovine rhinotracheitis (ibr) virus, would influence the pathogenesis of the bvdv infection sufficiently to result in the typical form of mucosal disease being produced. accordingly, two experiments were undertaken. in one experiment calves were first infected with bvdv and subsequ ... | 1992 | 1330424 |
| genetic relationships between bovine herpesvirus 4 and the gammaherpesviruses epstein-barr virus and herpesvirus saimiri. | the overall arrangement of genes in the unique central part of the bovine herpesvirus type 4 (bhv-4) genome has been deduced by analysis of short dna sequences. twenty-three genes conserved in at least one of the completely sequenced herpesviruses have been identified and localized. all of these genes encoded amino acid sequences with higher similarity to proteins of the gammaherpesviruses epstein-barr virus (ebv) and herpesvirus saimiri (hvs) than to the homologous products of the alphaherpesvi ... | 1992 | 1325698 |