Publications

fatal capnocytophaga canimorsus (df-2) septicaemia. a case report.	a 45-year-old man died 2 months after being bitten on the hand by a dog. he developed the rare but characteristic clinical picture of fulminant septicaemia and peripheral gangrene caused by a gram-negative bacillus, capnocytophaga canimorsus, previously known as dysgonic fermenter type 2 (df-2), which is an occasional commensal in the oral flora of dogs and cats. this disease must be anticipated and dog bites appropriately managed to avoid the mortality associated with infection by this micro-or ...	1994	7570239
dog, cat, and human bites: a review.	it is estimated that half of all americans will be bitten by an animal or another human being during their lifetimes. the vast majority of the estimated 2 million annual mammalian bite wounds are minor, and the victims never seek medical attention. nonetheless, bite wounds account for approximately 1% of all emergency department visits and more than $30 million in annual health care costs. infection is the most common bite-associated complication; the relative risk is determined by the species o ...	1995	7490347
rapid identification of capnocytophaga isolated from septicemic patients.	four capnocytophaga strains from blood cultures of immunocompromised patients with malignant disease and the type strains of three capnocytophaga species were examined and compared to strains representing five other genera that are hard to differentiate from capnocytophaga. with three rapid identification methods, negative catalase and oxidase reactions and positive onpg assay, capnocytophaga was easily separated from eikenella corrodens, actinobacillus actinomycetemcomitans, cardiobacterium hom ...	1984	6468367
infection with cdc group df-2 gram-negative rod: report of two cases.	two patients had bacteremia with center for disease control group df-2 gram-negative rods. previously described patients infected with this organism had clinical syndromes including cellulitis, meningitis, and endocarditis, and generally were severely ill. one of our patients had acute oligoarticular arthritis. the other had fever, headache, malaise, and a generalized rash. in neither case was bacterial infection considered likely at onset, and neither patient received antibiotic therapy. both p ...	1980	6249227
genomic relationships and species differentiation in the genus capnocytophaga.	ten epidemiologically independent capnocytophaga strains from clinical materials constituted three distinct dna homology groups corresponding to the established species, capnocytophaga ochracea, sputigena, and gingivalis. the three groups exhibited only low, or even insignificant degrees of genomic relatedness mutually, and to a reference culture of cdc group df-2. all of five capnocytophaga ochracea strains considered were involved in topic infections whereas four strains, isolated from blood b ...	1987	3439382
capnocytophaga canimorsus sp. nov. (formerly cdc group df-2), a cause of septicemia following dog bite, and c. cynodegmi sp. nov., a cause of localized wound infection following dog bite.	cdc group df-2 is the vernacular name given to a slow-growing gram-negative bacterium that causes septicemia and meningitis in humans. infections frequently (one-third of cases) occur following dog bites or close contact with dogs or occasionally with cats. splenectomy and alcoholism appear to be strong predisposing factors for df-2 infection. in addition to 150 df-2 strains received for identification, we received 9 df-2-like strains; 6 were isolated from wound or eye infections, 3 of which wer ...	1989	2915017
susceptibility testing of danish isolates of capnocytophaga and cdc group df-2 bacteria.	twelve capnocytophaga and seven df-2 strains were tested for their susceptibility to 14 antimicrobial agents using an agar dilution and an agar diffusion method. twenty-three other antibiotics were evaluated using the diffusion test only. all strains were fully susceptible to penicillin, ampicillin, cefuroxime, cefotaxime, erythromycin, clindamycin, chloramphenicol, doxycycline, rifamycin and ofloxacin using both methods. clindamycin, rifamycin and cefotaxime were most active. using agar dilutio ...	1989	2914105
precipitous hypotension in the emergency department caused by capnocytophaga canimorsus sp nov sepsis.	a 20-year-old man presented to the emergency department (ed) with an injured right hand, fever, and a history of dog exposure. this splenectomized individual developed hypotension less than 90 minutes after arriving in the ed with normal vital signs. he later developed overwhelming sepsis, gangrene, disseminated intravascular coagulation (dic), respiratory insufficiency, retroperitoneal hematoma, and renal insufficiency. blood cultures grew capnocytophaga canimorsus sp nov (formerly dysgonic fer ...	1990	2363753
capnocytophaga canimorsus as the cause of a chronic corneal infection.		1990	2301546
capnocytophaga canimorsus (formerly df-2) infections: review of the literature.		1990	2203978
[pasteurella multocida infections: bites by dogs or cats?].	annually 50,000 to 100,000 animal bites are seen by physicians in the netherlands. infections of these bite wounds frequently occur. pasteurella multocida is one of the main causes of these infections and many serious complications may occur. we present 3 patients with disturbances in wound healing after animal bites or scratches due to infection with p. multocida. in view of the high infection ratio after cat bites we advise giving amoxicillin/clavulanic acid (augmentin) for 5 days as prophylax ...	1991	2002857
a syndrome resembling thrombotic thrombocytopenic purpura associated with capnocytophaga canimorsus septicemia.		1991	1986580
fatal capnocytophaga canimorsus septicemia in a previously healthy woman.	a previously healthy 47-year-old woman presented to the emergency department with septic shock five days after a small dog bite on the dorsum of her hand. capnocytophaga canimorsus was isolated from blood cultures. despite intensive therapy, multiple organ failure developed, and the patient died 27 days after admission. characteristics of capnocytophaga (formerly cdc group dysgonic fermenter-2) infection are briefly discussed. this unusual outcome in a previously healthy patient and the need for ...	1991	1984739
infections resulting from animal bites.	animal bites are a major public health problem. this article reviews the epidemiology and treatment of animal bites. the epidemiology, clinical presentation, and treatment of infections caused by pasteurella multocida and capnocytophaga canimorsus (df-2) are reviewed in detail.	1991	1955705
purpura fulminans and symmetrical peripheral gangrene caused by capnocytophaga canimorsus (formerly df-2) septicemia--a complication of dog bite.	we review the syndrome of capnocytophaga canimorsus (df-2) septicemia after exposure to dogs or cats. we describe a previously healthy patient who developed diffuse intravascular coagulation and symmetrical peripheral gangrene as a result of c. canimorsus septicemia after a dog bite. to our knowledge, this patient was the first to receive combined plasmapheresis and leukapheresis for c. canimorsus septicemia. symmetrical peripheral gangrene is frequently associated with c. canimorsus septicemia ...	1991	1921703
secretory diarrhea following a dog bite.	overwhelming sepsis is rarely complicated by secretory diarrhea. we present a case of fulminant sepsis associated with dermatologic manifestations, disseminated intravascular coagulation (dic), and a severe secretory diarrhea that has not previously been described. this followed a dog bite, and the patient was otherwise healthy. the combination of septic shock, skin lesions, and dic occurring after a dog bite has been attributed to dysgonic fermentor 2 organisms, now called capnocytophaga canimo ...	1991	1864208
capnocytophaga canimorsus septicemia caused by a dog bite in a hairy cell leukemia patient.	fatal septicemia developed in a splenectomized patient with hairy cell leukemia following a dog bite. capnocytophaga canimorsus, a slowly growing gram-negative bacillus, was isolated from the patient's blood. although a rare complication of dog bites in the normal population, this bacterium should be suspected and promptly treated in immunologically compromised dog bite victims. furthermore, immunocompromised patients should be made aware of the dangers of dog ownership.	1992	1734053
isolation and identification of capnocytophaga canimorsus (df-2) from blood culture.		1991	1677720
capnocytophaga canimorsus infection after dog-bite.		1991	1672932
fulminant capnocytophaga canimorsus (df-2) septicaemia.		1991	1671152
fatal septicemia with capnocytophaga canimorsus in a compromised host. a case report with review of the literature.	capnocytophaga canimorsus (df-2) is a newly described gram-negative bacterium that can produce serious infections following dog bites in the immunocompromised host. we are reporting a case of c. canimorsus infection in an elderly patient with a history of chronic respiratory disease and alcohol abuse. we also give a review of the clinical spectrum of the infection, discuss the difficulty in establishing the diagnosis and the preferential treatment.	1991	1665939
dog-bite induced capnocytophaga canimorsus septicaemia.		1992	1580872
capnocytophaga canimorsus endocarditis.	we report a case of aortic valve endocarditis, caused by capnocytophaga canimorsus (previously known as cdc group df-2) secondary to a dog bite. vegetations were documented by cross-sectional echocardiography and bacteraemia by positive haemocultures for this unusual gram-negative bacillus.	1992	1577022
bite wounds and infection.	one of every two americans will be bitten by an animal or by another person at some point. bites account for approximately 1% of all visits to emergency rooms; injuries inflicted by dogs are most common. the bacteria involved in infection of bite wounds include pasteurella multocida, staphylococcus aureus, staphylococcus intermedius, alpha-hemolytic streptococci, capnocytophaga canimorsus, and other members of the oral flora. anaerobic bacteria are present in approximately one-third of bite woun ...	1992	1562653
capnocytophaga canimorus infection and acute renal failure.		1992	1522317
pleural infection caused by capnocytophaga canimorsus, formerly cdc group df-2.	an 80-year-old man with waldenström's macroglobulinemia developed pneumonia and empyema due to capnocytophaga canimorsus (formerly cdc group df-2). no growth was detected in blood cultures, but the organism was identified from cultures of pleural fluid. the infection responded well to antibiotics and drainage via a chest tube. to our knowledge, this is the first report of a clinical isolate of c. canimorsus from a pulmonary source. the absence of concurrent bacteremia raises the possibility that ...	1992	1520767
infective endocarditis with involvement of the tricuspid valve due to capnocytophaga canimorsus.	a case of endocarditis with vegetations on the tricuspid valve caused by capnocytophaga canimorsus is described. extensive diagnostic investigations preceded the diagnosis, including blood cultures, 34 of which were sterile. a possible role of the pulmonary circulation in the negative blood cultures is discussed.	1992	1468422
capnocytophaga canimorsus septicemia associated with cat scratch.	a case is reported of capnocytophaga canimorsus (formerly cdc group df-2) septicemia following cat scratch in a patient with congenital asplenia. the case is of interest in that (1) the clinical presentation provided no indication as to the cause of the patient's illness. (2) c. canimorsus infection following cat bite or scratch has been reported far less frequently than following dog bite. (3) the clinical course of the illness may have been modified by previous and concurrent warfarin therapy.	1992	1437293
opportunistic capnocytophaga canimorsus infection.		1992	1346312