Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
|---|
| transplacental transmission of human papillomavirus. | despite the increasing evidence of human papillomavirus (hpv) vertical transmission, this route is regarded as less clinically important because of the detections of transient hpv dna. however, recent studies have provided clear evidence of papillomavirus productive infection in lymphocytes, placenta, and bovine fetal tissue. furthermore, a model of papillomavirus latency has been recently proposed that could explain the failure or transience in hpv detection observed in some infected infants. t ... | 2015 | 28275411 |
| the deacetylase sirt1 regulates the replication properties of human papillomavirus 16 e1 and e2. | human papillomaviruses (hpv) replicate their genomes in differentiating epithelium using the viral proteins e1 and e2 in association with host proteins. while the roles of e1 and e2 in this process are understood, the host factors involved and how they interact with and regulate e1-e2 are not. our previous work identified the host replication and repair factor topbp1 as an e2 partner protein essential for optimal e1-e2 replication and for the viral life cycle. the role of topbp1 in host dna repl ... | 2017 | 28275188 |
| human papillomavirus (hpv) vaccine initiation in minority americans. | transmission of the human papillomavirus (hpv) is a significant public health concern. hpv is preventable through a series of vaccinations; however, knowledge gaps exist as to which groups are least likely to initiate vaccination. considering this gap, the aim of this study is to examine hpv vaccine initiation rates in racial minorities, comparing foreign-born individuals to their american-born peers. | 2017 | 28274389 |
| ano-genital warts and hiv status- a clinical study. | ano-genital warts (agw) like other sexually transmitted diseases (std) is associated with human immunodeficiency virus (hiv) infection. this study of agw was done in hiv positive and hiv negative patients. | 2017 | 28274028 |
| comparison of posttransplant dermatologic diseases by race. | the risk for skin cancer has been well characterized in white organ transplant recipients (otrs); however, most patients on the waiting list for organ transplant in the united states are nonwhite. little is known about cutaneous disease and skin cancer risk in this otr population. | 2017 | 28273280 |
| glycyrrhiza uralensis water extract enhances dendritic cell maturation and antitumor efficacy of hpv dendritic cell-based vaccine. | licorice has been used as herbal medicine and natural sweetener. here, we prepared glycyrrhiza uralensis water extract (guwe) and investigated the effect of guwe on the maturation and function of dendritic cells (dcs) and its adjuvant effect on dc-based vaccine. we observed that guwe dose-dependently promoted dc maturation and cytokine secretion through tlr4 signaling pathway. the capacity of dc to stimulate allogenic splenocyte proliferation was also enhanced by guwe treatment. compared with co ... | 2017 | 28272545 |
| colorimetric detection of 23 human papillomavirus genotypes by loop-mediated isothermal amplification. | human papillomavirus (hpv) infection is linked to cervical cancer. with the technological development of molecular biology and epidemiology, detection and treatment of hpv has become an important mean to prevent cervical cancer. | 2017 | 28271692 |
| human papillomavirus (hpv) e6/e7 mrna detection in cervical exfoliated cells: a potential triage for hpv-positive women. | cytology triage has been generally recommended for human papillomavirus (hpv)-positive women, but is highly dependent on well-trained cytologists. the present study was designed to explore whether hpv e6/e7 mrna detection in cervical exfoliated cells can be a potential triage for hpv-positive women from a clinic-based population. both the primary hpv testing and papanicolaou (pap) test were performed on all eligible hpv-positive women. hpv e6/e7 mrna was detected by quantivirus(®) hpv e6/e7 mrna ... | 2017 | 28271661 |
| prognostic value of human papillomavirus 16/18 genotyping in low-grade cervical lesions preceded by mildly abnormal cytology. | histological low-grade squamous intraepithelial lesion/cervical intraepithelial neoplasia grade 1 (lsil/cin1) preceded by normal or mildly abnormal cytology is recommended for conservative follow-up, with no separated management. in this study, we assessed the triage value of human papillomavirus (hpv) 16/18 genotyping in 273 patients with lsil/cin1. hpv16/18 genotyping was performed at baseline and follow-up was at 6-monthly intervals for up to 2 years. at each follow-up, women positive for cyt ... | 2017 | 28271660 |
| outcomes of hpv-related nasal squamous cell carcinoma. | human papilloma virus (hpv) infection has been shown to play an integral role in the development and prognosis of various head and neck cancers. generational changes in sexual behavior may have led to an increased incidence of positivity in recent years. hpv positivity in both benign and malignant lesions of the sinonasal cavities has been shown in previous studies (estimates range from 20%-30% for malignancy). we intend to investigate if hpv positivity affected survival outcomes in our patient ... | 2017 | 28271500 |
| confirmation of the eighth edition of the ajcc/uicc tnm staging system for hpv-mediated oropharyngeal cancer in japan. | several studies have demonstrated that the seventh edition of the american joint committee on cancer/american joint committee on cancer (ajcc/uicc) tnm staging system does not consistently distinguish between prognostic subgroups for human papillomavirus (hpv)-mediated oropharyngeal squamous cell carcinoma (opscc). the eighth edition of the ajcc/uicc tnm staging system came into effect for use with hpv-mediated opscc on or after 1 january 2017. this study confirms that the eighth edition of the ... | 2017 | 28271391 |
| solitary endobronchial papilloma with malignant transformation and concomitant tb infection: case report and literature review. | we are reporting a case of solitary endobronchial papilloma located in posterior segment of the left upper lobe of the lung with malignant transformation and negative human papilloma virus (hpv) strains in a 40-year-old saudi nonsmoker man. the patient had a concomitant tuberculosis (tb) infection. the patient received appropriate treatment in the form of anti-tb medication and surgical resection of the squamous cell carcinoma followed by chemotherapy. there was no evidence of tumor recurrence, ... | 2017 | 28270942 |
| options in human papillomavirus (hpv) detection for cervical cancer screening: comparison between full genotyping and a rapid qualitative hpv-dna assay in ghana. | modern cervical cancer screening increasingly relies on the use of molecular techniques detecting high-risk oncogenic human papillomavirus (hr-hpv). a major challenge for developing countries like ghana has been the unavailability and costs of hpv dna-based testing. this study compares the performance of carehpv, a semi-rapid and affordable qualitative detection assay for 14 hr-hpv genotypes, with hpv genotyping, for the detection of cytological cervical squamous intraepithelial lesions (sil). | 2017 | 28270915 |
| genetic variability in e6, e7 and l1 genes of human papillomavirus 62 and its prevalence in mexico. | human papillomavirus (hpv) is the main etiological agent of cervical cancer, the third most common cancer among women globally and the second most frequent in mexico. persistent infection with high-risk hpv genotypes is associated with premalignant lesions and cervical cancer development. hpvs considered as low risk or not yet classified, are often found in coinfection with different hpv genotypes. indeed, hpv62 is one of the most prevalent hpv detected in some countries, but there is limited in ... | 2017 | 28270859 |
| effects of a non-thermal plasma needle device on hpv-16 positive cervical cancer cell viability in vitro. | non-thermal atmospheric pressure plasma has been demonstrated to inactivate a wide range of surface-dwelling pathogenic microorganisms including airborne viral particles, vegetative bacteria and bacterial spores. this shows the promise of plasma-based decontamination procedures for broad-spectrum sterilization and disinfection and promotes the in-depth and systematic study of how plasma treatment conditions relate to pathogen inactivation efficiency. a wide knowledge gap nonetheless exists regar ... | 2016 | 28268388 |
| stop codon mutagenesis for homogenous expression of human papillomavirus l1 protein in escherichia coli. | human papillomavirus (hpv) is widely accepted to be the major causative pathogen of cervical cancer, warts, and other epithelial tumors. virus infection and subsequent disease development can be prevented by vaccination with hpv vaccines derived from eukaryotic expression systems. here, we report the soluble expression of the major capsid protein l1 of hpv31, a dominant carcinogenic hpv genotype, in escherichia coli. hpv31 l1 protein and its elongated form (l1+) were observed in sds-page and ce- ... | 2017 | 28267627 |
| a case of penile buschke-lowenstein tumor in a developing country. | buschke-löwenstein tumor is a rare manifestation of a sexually transmitted human papilloma virus infection that affects the anogenital area. wide local excision of the lesion is the mainstay of treatment. malignancy though must be excluded. | 2017 | 28265385 |
| high-risk and low-risk human papilloma virus in association to spontaneous preterm labor: a case-control study in a tertiary center, egypt. | this study aimed to detect the correlation between human papillomavirus (hpv) and spontaneous preterm labor in egyptian women and its association to the human papilloma viral load and mpp2 gene expression. | 2017 | 28264621 |
| human papillomavirus vaccine as an anticancer vaccine: collaborative efforts to promote human papillomavirus vaccine in the national comprehensive cancer control program. | widespread use of the human papillomavirus (hpv) vaccine has the potential to reduce incidence from hpv-associated cancers. however, vaccine uptake among adolescents remains well below the healthy people 2020 targets. the centers for disease control and prevention (cdc) national comprehensive cancer control program (ncccp) awardees are well positioned to work with immunization programs to increase vaccine uptake. the cdc chronic disease management information system was queried for objectives an ... | 2017 | 28263672 |
| ahns series: do you know your guidelines? management of head and neck cancer in the era of human papillomavirus: educating our patients on human papillomavirus. | human papillomavirus (hpv) has changed the face of head and neck cancer over the past 2 decades. no longer is this solely a disease of older patients with a history of heavy tobacco and alcohol use. patients with hpv-related head and neck cancers tend to be younger, healthier, and have an improved prognosis, compared with those with hpv-negative tumors. as more patients are diagnosed with hpv-related head and neck cancer, physicians have important topics to consider. these include prevalence, tr ... | 2017 | 28263449 |
| development of a replication-deficient adenoviral vector-based vaccine candidate for the interception of hpv16- and hpv18-induced infections and disease. | high-risk human papilloma virus (hpv) types are the causative agents of cervical cancer and several other anogenital malignancies. the viral proteins expressed in the (pre)malignant cells are considered ideal targets for immunological intervention. many approaches have been evaluated for this purpose, mostly aiming at the induction of hpv16 e7- and/or e6-specific cellular immunogenicity. as clinical success has so far been limited, novel approaches are required. we describe the development and p ... | 2017 | 28263390 |
| the presence of human papillomavirus in semen does not affect the integrity of sperm dna. | it remains unknown whether human papillomaviruses (hpvs) in semen affect sperm dna integrity. we investigated whether the presence of these viruses in semen was associated with an elevated sperm dna fragmentation index. semen samples of 22 normozoospermic patients undergoing infertility treatment, nine fertile donors and seven fertile men with a risk of hpv infection (genital warts or condylomas) were included in the study. the samples were examined by an inno-lipa test pcr-based reverse hybridi ... | 2017 | 28261849 |
| using twitter to understand public perceptions regarding the #hpv vaccine: opportunities for public health nurses to engage in social marketing. | given the degree of public mistrust and provider hesitation regarding the human papillomavirus (hpv) vaccine, it is important to explore how information regarding the vaccine is shared online via social media outlets. the purpose of this study was to evaluate the content of messaging regarding the hpv vaccine on the social media and microblogging site twitter, and describe the sentiment of those messages. | 2017 | 28261846 |
| establishment and characterization of a squamous cell carcinoma cell line, designated hzk-1, derived from a metastatic lymph node tumor of the tongue. | the hzk-1 cell line was successfully established from the metastatic foci of a lymph node of an 82-year-old japanese woman with squamous cell carcinoma of the tongue. the pathological diagnosis of the tumor was moderately to well-differentiated squamous cell carcinoma. the hzk-1 cells were angular in shape, and had neoplastic and pleomorphic features. adjacent hzk-1 cells were joined by desmosomes and well-developed microvilli, and many free ribosomes were observed in the cytoplasm. the doubling ... | 2017 | 28260147 |
| hpv16 oncogenes e6 or/and e7 may influence the methylation status of rassfia gene promoter region in cervical cancer cell line ht-3. | both human papillomavirus (hpv) infection and the aberrant ras associated domain family gene 1a (rassf1a) promoter methylation status participate in the pathogenesis of cervical cancer. some studies suggest that e6, and e7 are involved in the pathogenetic mechanisms of rassf1a. we mainly explored a possible involvement of hpv16 oncogenes e6 or/and e7 in rassf1a promoter methylation status and possible roles of rassf1a gene methylation in cervical cancer. bisulfite genomic sequencing (bgs) pcr co ... | 2017 | 28260046 |
| neuroimmune mechanisms of behavioral alterations in a syngeneic murine model of human papilloma virus-related head and neck cancer. | patients with cancer often experience a high symptom burden prior to the start of treatment. as disease- and treatment-related neurotoxicities appear to be additive, targeting disease-related symptoms may attenuate overall symptom burden for cancer patients and improve the tolerability of treatment. it has been hypothesized that disease-related symptoms are a consequence of tumor-induced inflammation. we tested this hypothesis using a syngeneic heterotopic murine model of human papilloma virus ( ... | 2017 | 28259044 |
| re-evaluation of ipsilateral radiation for t1-t2n0-n2b tonsil carcinoma at the princess margaret hospital in the human papillomavirus era, 25 years later. | to report the outcome of ipsilateral radiation therapy (rt) in human papillomavirus (hpv)-positive (hpv+) patients and hpv-negative (hpv-) patients with t1-t2n0-n2b tonsillar cancer treated 25 years after our initial historical cohort. | 2017 | 28258895 |
| exploring the impact of human papillomavirus status, comorbidity, polypharmacy, and treatment intensity on outcome of elderly oropharyngeal cancer patients treated with radiation therapy with or without chemotherapy. | to explore the impact of tumor human papillomavirus (hpv) status, comorbidity, polypharmacy, and treatment intensity on overall survival (os) of elderly oropharyngeal cancer (opc) patients. | 2016 | 28258893 |
| viruses in case series of tumors: consistent presence in different cancers in the same subject. | studies investigating presence of viruses in cancer often analyze case series of cancers, resulting in detection of many viruses that are not etiologically linked to the tumors where they are found. the incidence of virus-associated cancers is greatly increased in immunocompromised individuals. non-melanoma skin cancer (nmsc) is also greatly increased and a variety of viruses have been detected in nmsc. as immunosuppressed patients often develop multiple independent nmscs, we reasoned that virus ... | 2017 | 28257474 |
| determinants of geographic inequalities in hpv vaccination in the most populated region of france. | in france, there are recommendations and reimbursements for human papillomavirus (hpv) vaccination but no hpv vaccination programs. therefore, vaccination is largely determined by parents' initiative, which can lead to inequalities. the objective of this study was to determine the factors associated with poorer vaccination coverage rates in the most populated region of france. | 2017 | 28257434 |
| implementing a multipartner hpv vaccination assessment and feedback intervention in an integrated health system. | human papillomavirus (hpv) vaccine initiation rates are persistently lower than rates for other adolescent-recommended vaccines. assessment and feedback interventions are a recommended strategy for improving vaccination rates. | 2017 | 28257408 |
| human papillomavirus co-testing results effectively triage normal cervical cytology in hiv-positive women aged 30 years and older. | the aim of the study was to assess whether hiv-positive (hiv+) women aged 30 years and older with concurrent normal cervical cytology and undetectable cervical hpv have a low 3-year risk of developing cervical intraepithelial neoplasia grade 2 or higher (cin 2+) in a clinical setting. | 2017 | 28257290 |
| a pilot study into the association between oral health status and human papillomavirus-16 infection. | over the next 20 years, oropharyngeal cancers (opc) will represent the majority of head and neck cancers (hncs) in the united states. it is estimated that human papillomavirus (hpv) may account for as much as 70% to 80% of opcs in north america and in certain parts of europe. it is hence crucial to understand the disease risk factors and natural history of oral hpv infections. we hypothesized that poor oral health (by measures such as poor oral hygiene and periodontal disease) leads to a higher ... | 2017 | 28257064 |
| human papillomavirus vaccine uptake: increase for american indian adolescents, 2013-2015. | although indian health service, tribally-operated, and urban indian (i/t/u) healthcare facilities have higher human papillomavirus (hpv) vaccine series initiation and completion rates among adolescent patients aged 13-17 years than the general u.s. population, challenges remain. i/t/u facilities have lower coverage for hpv vaccine first dose compared with coverage for other adolescent vaccines, and hpv vaccine series completion rates are lower than initiation rates. researchers aimed to assist i ... | 2017 | 28256284 |
| gene promoter-associated cpg island hypermethylation in squamous cell carcinoma of the tongue. | the present study was undertaken to explore and validate novel hypermethylated dna regions in squamous cell carcinoma of the tongue (scct). genome-wide methylation changes were identified by differential methylation hybridization (dmh) microarray and validated by bisulfite genome sequencing (bgs). the results were compared against datasets from the cancer genome atlas head and neck squamous cell carcinoma (tcga-hnscc), gene expression omnibus (gse26549), and arrayexpress (e-mtab-1328). dmh ident ... | 2017 | 28255813 |
| anal intraepithelial neoplasia: a review of diagnosis and management. | anal intraepithelial neoplasia (ain) is a premalignant lesion of the anal mucosa that is a precursor to anal cancer. although anal cancer is relatively uncommon, rates of this malignancy are steadily rising in the united states, and among certain high risk populations the incidence of anal cancer may exceed that of colon cancer. risk factors for ain and anal cancer consist of clinical factors and behaviors that are associated with the acquisition and persistence of human papilloma virus (hpv) in ... | 2017 | 28255426 |
| human papillomavirus infection and cervical lesions in hiv infected women on antiretroviral treatment in thailand. | to estimate the prevalence and factors associated with human papillomavirus (hpv) infection, hpv genotypes and cytological/histological high-grade (hsil+/cin2+) lesions. | 2017 | 28254419 |
| hiv-associated anal dysplasia and anal carcinoma. | anal carcinoma shows an increasing incidence in people living with human immunodeficiency virus (hiv) and acquired immune deficiency syndrome (aids) in whom it is also much more common compared to the hiv-negative population. human papillomavirus infection is the etiological basis of malignant development in the anal epithelium. therefore, adequate diagnosis and treatment of the precursor lesions (anal intraepithelial neoplasia) is of clinical importance. in cases with preserved immune function, ... | 2017 | 28253522 |
| autophagy regulates ubc9 levels during viral-mediated tumorigenesis. | ubc9, the sole e2-conjugating enzyme required for sumoylation, is a key regulator of essential cellular functions and, as such, is frequently altered in cancers. along these lines, we recently reported that its expression gradually increases during early stages of human papillomavirus (hpv)-mediated cervical lesions transformation. however, a better understanding of how ubc9 is exploited by transforming viral oncoproteins is still needed. in the present study, we show that in human samples hpv d ... | 2017 | 28253371 |
| beta human papillomavirus infection is prevalent in elephantiasis and exhibits a productive phenotype: a case-control study. | elephantiasis is considered a cutaneous region of immune deficiency with cobblestone-like surface caused by a wart-like eruption. verrucosis is a diffuse human papillomavirus (hpv) infection linked to immunodeficiency disorders. the objective of this study was to examine the prevalence of hpv infection in lymphedema and its pathogenic role in elephantiasis. a retrospective case-control study was performed examining lymphedematous skin and controls of peritumoral normal skin. hpv infection was ev ... | 2017 | 28253203 |
| eyelid verrucous carcinoma. | to report a case of verrucous carcinoma (vc) that presented as an eyelid mass on the right eye. | 2017 | 28252698 |
| [the analysis of the effectiveness of the combined treatment of the patients presenting with laryngeal papillomatosis]. | the objective of the present work was to evaluate the effectiveness of the application of the inducer of endogenous interferon synthesis in the course of the combined treatment of the adult patients presenting with laryngeal papillomatosis. a total of 50 patients with this pathology were admitted and examined at the ent clinics of i.m. sechenov first moscow state medical university and m.f. vladimirsky moscow regional research clinical institute during 24 months. the patients comprising group 1 ... | 2017 | 28252590 |
| risk factors of high-grade anal intraepithelial neoplasia recurrence in hiv-infected men who have sex with men. | to assess risk factors of high-grade anal intraepithelial neoplasia (hgain) recurrence in a cohort of hiv-infected men who have sex with men (msm). | 2017 | 28252530 |
| the prevalence of viral agents in esophageal adenocarcinoma and barrett's esophagus: a systematic review. | human papilloma virus (hpv), which may reach the esophagus through orogenital transmission, has been postulated to be associated with esophageal adenocarcinoma (eac). a systematic review of the literature investigating the prevalence of infectious agents in eac and barrett's esophagus (be) was carried out. | 2017 | 28252462 |
| the role of transoral robotic surgery in the management of oropharyngeal cancer. | the rising incidence of oropharyngeal squamous cell carcinoma (opscc), in large part as a result of the human papillomavirus (hpv), has driven a movement for the change in the management strategies. renewed interest in minimally invasive approaches of endoscopic head and neck surgery led to introduction of transoral surgery, including transoral robotic surgery (tors). | 2017 | 28252460 |
| ipa analysis of cervicovaginal fluid from precancerous women points to the presence of biomarkers for the precancerous state of cervical carcinoma. | despite large gaps in our knowledge on the intracellular mechanism leading to cervical cancer, the pathways induced by oncogenic high-risk human papilloma virus (hpv) and those finally causing cervical cancer are increasingly being unraveled. assuming that precancerous tissue is recognized and lysed by the immune system-which is in many cases incomplete because of the counteraction by the hpv virus-we hypothesize that several intracellular factors, involved in induction and development of precan ... | 2014 | 28250389 |
| comparison of ffpe histological versus lbp cytological samples for hpv detection and typing in cervical cancer. | human papillomavirus (hpv) infection is closely associated with cervical cancer. this study analyzed hpv genotype prevalence in 75 cases of formalin-fixed paraffin embedded (ffpe) tissue samples from patients diagnosed with cervical cancer. genotype prevalence was assessed using reverse blot assay (reba) and quantitative polymerase chain reaction (qpcr), which target the hpv l1 and hpv e6/e7 genes, respectively. hpv dna chip tests were also performed using liquid based preparation (lbp) cytologi ... | 2017 | 28249711 |
| transoral robotic surgery for management of cervical unknown primary squamous cell carcinoma: updates on efficacy, surgical technique and margin status. | management of cervical unknown primary squamous cell carcinoma (cup) has evolved with the introduction of transoral robotic surgery (tors). | 2017 | 28249654 |
| validation of the icon-s staging for hpv-associated oropharyngeal carcinoma using a pre-defined treatment policy. | to determine whether the international collaboration on oropharyngeal cancer network for staging (icon-s) for hpv associated oropharyngeal carcinoma (hpv+opc) is a better discriminator of overall survival (os), compared with the 7th edition (7th ed) ajcc/uicc tnm staging following curative radiotherapy (rt). | 2017 | 28249652 |
| prevalence of human papillomavirus in tonsil brushings and gargles in cancer-free patients: the split study. | to evaluate human papillomavirus (hpv) prevalence in the tonsil using extensive ex vivo brushing and gargling in a large age-stratified sample of cancer-free patients. | 2017 | 28249648 |
| women's health care: the experiences and behaviors of rural and urban lesbians in the usa. | previous research has consistently demonstrated that, in comparison to their cisgender heterosexual counterparts, lesbians face a multitude of women's healthcare-related disparities. however, very little research has been conducted that takes an intersectionality approach to examining the potential influences of rural-urban location on the health-related needs and experiences of lesbians. the purpose of this study was to quantitatively compare rural and urban lesbians' access to women's health c ... | 2017 | 28248528 |
| [interferon in combined therapy of human papillomavirus infections associated with sexually transmitted infections. linical observation]. | to investigate the effectiveness of ingaron (interferon-) in the treatment of hpv infection associated with sexually transmitted infections, the authors analyzed the scientific literature on the association of human papillomavirus infection with other viral and microbial pathogens. a clinical case of the association of human papillomavirus infection, urogenital infections (urogenital chlamydia and genital herpes) and localized scleroderma penis is described. the results of integrated therapy of ... | 2016 | 28248030 |
| [anogenital warts: a new way of solving the common problem of urology (results of long-term follow-up)]. | to evaluate the effectiveness of combined use of the imiquimod 5% cream and vaccination against human papillomavirus (hpv) using a quadrivalent recombinant vaccine to achieve long-term clinical remission of chronic hpv infection manifested by anogenital warts. | 2016 | 28248020 |
| [combined treatment of genital human papillomavirus infection in men]. | this study aimed to assess the efficacy of treatment of genital human papillomavirus infection in 107 men. patients in group 1 (n=51) underwent laser ablation of genital warts, patients in group 2 (n=56) were treated with laser ablation in conjunction with the administration of an immune system medication izoprinozin. during the first 9 months post-treatment, human papillomavirus infection relapse rate in group 1 was 23,5% and in group 2 - 5,4%. it was likewise observed that the combined treatme ... | 2015 | 28247678 |
| [the role of viruses in the etiology of bladder cancer]. | currently, debate continues about the etiological role of pathogens, in particular viruses, in the development of bladder tumors, their impact on the rate of recurrence and invasive and metastatic forms. the etiological role of high-risk human papillomavirus (hpv) in squamous carcinoma of the cervix and upper respiratory tract is considered proven. however, some published studies show the role of oncogenic hpv in causing bladder cancer, its invasiveness and metastasizing. the review is dedicated ... | 2016 | 28247638 |
| introduction of liquid-based cytology and human papillomavirus testing in cervical cancer screening in luxembourg. | in 2014, liquid-based cytology with hpv triage replaced conventional cytology. the aim of our study was to compare conventional and liquid-based cytology (lbc), estimate the prevalence of abnormal cervical cytology and high risk hpv (hrhpv) infection and their correlation, among screened women in luxembourg. | 2017 | 28247516 |
| update from the 4th edition of the world health organization classification of head and neck tumours: tumors of the nasal cavity, paranasal sinuses and skull base. | the sinonasal tract remains an epicenter of a diverse array of neoplasia. this paper discusses changes to the who classification system of tumors involving this area. in particular, seromucinous hamartoma, nut carcinoma, biphenotypic sinonasal sarcoma, hpv-related carcinoma with adenoid cystic features, smarcb1-deficient carcinoma, and renal cell-like adenocarcinoma are discussed. | 2017 | 28247233 |
| update from the 4th edition of the world health organization classification of head and neck tumours: what is new in the 2017 who blue book for tumours of the hypopharynx, larynx, trachea and parapharyngeal space. | chapter 3 "tumours of the hypopharynx, larynx, trachea, and parapharyngeal space" of the world health organization (who) blue book 2017 "classification of head and neck tumours" shows a shortened list of entities, especially due to reducing the number of benign and malignant soft tissue tumours, malignant melanoma and some others, which are transferred to more frequently affected regions of the head and neck. the basic concept of the new edition is to assimilate all advances concerning the discu ... | 2017 | 28247231 |
| update from the 4th edition of the world health organization classification of head and neck tumours: oropharynx. | the changes for oropharyngeal lesions in the 2017 edition of the who/iarc classification of head and neck tumours reference book are dramatic and significant, largely due to the growing impact of high risk human papillomavirus (hpv). the upcoming edition divides tumours of the oral cavity and oropharynx into separate chapters, classifies squamous cell carcinomas (scc) of the oropharynx on the basis of hpv status, abandons the practice of histologic grading for oropharyngeal sccs that are hpv pos ... | 2017 | 28247229 |
| update from the 4th edition of the world health organization classification of head and neck tumours: what is new in the 2017 who blue book for tumors and tumor-like lesions of the neck and lymph nodes. | the world health organization (who) 2017 classification of head and neck tumors ("blue book") will now include a new chapter on tumors and tumor-like lesions of the neck and lymph nodes, which was not included in the previous edition. tumors and tumor-like lesions, including a variety of cysts and metastases, can arise in any component in the neck, including soft tissue, lymph nodes, and developmental remnants. the pathology and clinical features of metastatic carcinoma of unknown primary in the ... | 2017 | 28247228 |
| the authors respond to "supporting the call for a gender-neutral human papillomavirus vaccination in canada". | 2017 | 28246157 | |
| supporting the call for a gender-neutral human papillomavirus vaccination in canada. | 2017 | 28246156 | |
| parents' views of including young boys in the swedish national school-based hpv vaccination programme: a qualitative study. | to explore parents' views of extending the human papillomavirus (hpv) vaccination programme to also include boys. | 2017 | 28246143 |
| no increased risk of guillain-barré syndrome after human papilloma virus vaccine: a self-controlled case-series study in england. | to investigate the risk of guillain-barré syndrome (gbs) after human papilloma virus (hpv) vaccine given to 12-18year old girls in england. | 2017 | 28245941 |
| the regulations of deubiquitinase usp15 and its pathophysiological mechanisms in diseases. | deubiquitinases (dubs) play a critical role in ubiquitin-directed signaling by catalytically removing the ubiquitin from substrate proteins. ubiquitin-specific protease 15 (usp15), a member of the largest subfamily of cysteine protease dubs, contains two conservative cysteine (cys) and histidine (his) boxes. usp15 harbors two zinc-binding motifs that are essential for recognition of poly-ubiquitin chains. usp15 is grouped into the same category with usp4 and usp11 due to high degree of homology ... | 2017 | 28245560 |
| radiologic differences between human papillomavirus-related and human papillomavirus-unrelated oropharyngeal carcinoma on diffusion-weighted imaging. | human papilloma virus-related oropharyngeal carcinoma (hpv+ opc) is a unique entity compared to hpv-unrelated (hpv-) opc. previous studies were inconclusive regarding the differences between hpv+ and hpv- opcs on diffusion-weighted imaging (dwi). this study sought to determine if there is an association between hpv status and apparent diffusion coefficient (adc) values as an imaging biomarker in opcs. | 2017 | 28245461 |
| human papillomavirus and the development of different cancers. | human papillomaviruses (hpv) are responsible for the development of almost all cervical cancers. hpv is also found in 85% of anal cancer and in 50% of penile, vulvar, and vaginal cancers, and they are increasingly found in a subset of head and neck cancers, i.e., oropharyngeal squamous cell carcinomas (opscc). the model for how hpv causes cancer is derived from several decades of study on cervical cancer, and it is just presumed that this model is not only completely valid for cervical cancer bu ... | 2016 | 28245440 |
| study of association and molecular analysis of human papillomavirus in breast cancer of indian patients: clinical and prognostic implication. | human papillomavirus (hpv) causes tumors primarily cervical cancer. recently, inconsistent reports came up in breast cancer (bc) too. in india, despite treatment 70,218 bc patients die each year. so, we explored the association of hpv, if any, with bc prognosis in indian pre-therapeutic (pt) and neo-adjuvant chemotherapy (nact) patients with subsequent analysis of hpv profile. | 2017 | 28245287 |
| hpv vaccine knowledge and acceptability among peruvian men who have sex with men and transgender women: a pilot, qualitative study. | human papillomavirus (hpv) is the most common sexually transmitted infection globally and is responsible for a variety of cancers in men and women. an effective hpv vaccine licensed for use in girls and boys has been indicated for-but is not widely implemented in-men who have sex with men (msm). limited data are available for transgender women (tw). we explored the social and behavioral aspects related to hpv vaccine uptake and participation in hpv vaccine studies among peruvian msm and tw. | 2017 | 28245234 |
| human papillomavirus/p16 positive head and neck cancer in india: prevalence, clinical impact, and influence of tobacco use. | limited data are available on the prevalence and prognostic significance of human papillomavirus (hpv) in squamous cell carcinoma of head and neck (scchn) in the indian population. | 2017 | 28244466 |
| increased serum antibody titer against hpv-16 antigen in patients with behçet's disease. | quadrivalent human papillomavirus (hpv) vaccine has been reported to be significantly associated with behçet's disease (bd). however, no reports have described hpv infection as a possible cause for the development of bd. the objective of this study was to evaluate whether anti-hpv immunoglobulin g (igg) antibody titer is increased in bd. serum samples from 93 korean bd patients, who fulfilled the diagnostic criteria of the international study group for bd, were used in an enzyme-linked immunosor ... | 2017 | 28244285 |
| e7 protein of cutaneous human papillomavirus attenuates viperin expression in human keratinocytes. | 2017 | 28242342 | |
| dysphagia-optimised intensity-modulated radiotherapy techniques in pharyngeal cancers: is anyone going to swallow it? | dysphagia after primary chemoradiotherapy or radiation alone in pharyngeal cancers can have a devastating impact on a patient's physical, social and emotional state. establishing and validating efficient dysphagia-optimised radiotherapy techniques is, therefore, of paramount importance in an era where health-related quality of life measures are increasingly influential determinants of curative management strategies, particularly as the incidence of good prognosis, human papillomavirus-driven pha ... | 2017 | 28242166 |
| the prognostic role of sex, race, and human papillomavirus in oropharyngeal and nonoropharyngeal head and neck squamous cell cancer. | human papillomavirus (hpv) is a well-established prognostic marker for oropharyngeal squamous cell cancer (opscc). because of the limited numbers of women and nonwhites in studies to date, sex and racial/ethnic differences in prognosis have not been well explored. in this study, survival differences were explored by the tumor hpv status among 1) patients with opsccs by sex and race and 2) patients with nonoropharyngeal (non-op) head and neck squamous cell cancers (hnsccs). | 2017 | 28241096 |
| the complex relation between race, sex, and human papillomavirus status in head and neck cancer. | 2017 | 28241091 | |
| use of a 2-dose schedule for human papillomavirus vaccination-updated recommendations of the advisory committee on immunization practices. | 2017 | 28240827 | |
| association of high risk human papillomavirus and breast cancer: a uk based study. | infection by human papillomaviruses (hpvs) has been implicated in the aetiology of a variety of cancers. studies evaluating the presence of hpvs in breast cancer (bc) have generated considerable controversy. to date, most studies have focused on the presence of viral dna in bc; however there are important gaps in evidencing the role of hpv persistence in the invasiveness of bc. while these studies have been conducted in several countries, none, on the presence and biological activity of high ris ... | 2017 | 28240743 |
| human papillomavirus genotypes and methylation of cadm1, pax1, mal and adcyap1 genes in epithelial ovarian cancer patients | background: high-risk types of human papillomavirus (hr-hpv) may play a role in the development of epithelial ovarian cancer (eoc). the aim of this study was to determine any hpv genotypes and correlations to cadm1, pax1, mal and adcyap1 gene methylation in egyptian eoc patients. materials and methods: the prevalence of hr-hpv in 100 formalin fixed paraffin embedded eoc tissues was determined using nested polymerase chain reaction (pcr) with my09/my11 and gp5+/gp6 + primers to amplify a broad sp ... | 2017 | 28240513 |
| community-based prevalence of genital human papilloma virus (hpv) infection: a systematic review and meta-analysis | introduction: cervical cancer probably represents the best-studied human cancer caused by a viral infection and the causal association of this preventable cancer with human papilloma virus (hpv) is well established. worldwide there is a scarcity of data regarding hpv prevalence with vast differences existing among populations. objective: the aim of this meta-analysis was to determine the community-based hpv prevalence estimates among asymptomatic women from urban and rural set ups and in partici ... | 2017 | 28240509 |
| hpv16 e6 seropositivity among cancer-free men with oral, anal or genital hpv16 infection. | antibodies against the human papillomavirus 16 (hpv16) e6 oncoprotein appear years prior to clinical diagnosis of anal and oropharyngeal cancer, but whether they develop around the time of hpv infection is unclear. serum samples from 173 cancer-free men from the human papillomavirus infection in men (him) study were tested for hpv antibodies and dna. hpv16 e6 seropositivity was low among men with oral hpv16-infection (1/28; 3.6%, 95%ci=0.0%-18.4%), anal hpv16-infection (1/61; 1.6%, 95%ci=0.0%-8. ... | 2016 | 28239675 |
| four-year persistence of type-specific immunity after quadrivalent human papillomavirus vaccination in hiv-infected children: effect of a fourth dose of vaccine. | although hiv-infected children are recommended to receive quadrivalent human papillomavirus vaccine (qhpv) there is limited information on their response to qhpv. this study in hiv-infected children, evaluated the magnitude and duration of immune responses to qhpv. this report describes type-specific serum antibody responses over a 4-to-5year period after either 3 or 4 doses of qhpv. | 2017 | 28238631 |
| socioeconomic inequalities to accessing vaccination against human papillomavirus in france: results of the health, health care and insurance survey, 2012. | in france, human papillomavirus (hpv) vaccination coverage among adolescents and young women is low and decreasing. we analysed data from the 2012 health, health care and insurance survey with the aim of identifying factors associated with this vaccination. we also compared the socioeconomic profile of unvaccinated young women to that of women who do not undergo cervical cancer screening (ccs). | 2017 | 28238476 |
| human papilloma virus dermatosis in human immunodeficiency virus-positive patients: a 14-year retrospective study in 965 patients. | the incidence of the human papilloma virus (hpv) has not dropped in hiv-positive patients despite the discovery of antiretroviral therapy (art). our goal is to assess the prevalence of hpv in hiv patients and its relationship with the epidemiological and virological characteristics of hiv patients. | 2017 | 28238336 |
| expression and clinical significance of high risk human papillomavirus and invasive gene in cervical carcinoma. | to study the expression of e6 and e7 mrna in high-risk human papillomavirus (hpv) hpv-18 and the relationship between the expression of invasive gene and cervical carcinoma. | 2017 | 28237489 |
| treatment of athlete's plantar warts using a botanical blend: a case report. | context • viral plantar warts, or verruca plantaris, are a benign epithelial tumor caused by various strains of the human papilloma virus (hpv). current treatments have had mixed degrees of success, are moderately invasive, and are often incompatible with participation in sports. objective • the study intended to examine the benefits of treating plantar warts with a topical, botanical blend that has had clinical success treating herpes simplex virus cold sores. methods • a synergistic botanical ... | 2017 | 28236614 |
| integration of high-risk human papillomavirus into cellular cancer-related genes in head and neck cancer cell lines. | human papillomavirus (hpv)-positive oropharyngeal cancer is generally associated with excellent response to therapy, but some hpv-positive tumors progress despite aggressive therapy. the purpose of this study was to evaluate viral oncogene expression and viral integration sites in hpv16- and hpv18-positive squamous cell carcinoma lines. | 2017 | 28236344 |
| role of ethnicity in human papillomavirus vaccination uptake: a cross-sectional study of girls from ethnic minority groups attending london schools. | research suggests that girls from ethnic minority groups are less likely to receive the human papillomavirus (hpv) vaccination than white british girls; however, the specific ethnic minority groups that have lower uptake have not been identified. this study aimed to examine the relationship between school-level uptake and ethnicity as well as uptake and other ethnicity-related factors, to understand which specific groups are less likely to receive the vaccination. | 2017 | 28235971 |
| preventing human papillomavirus-related cancers: we are all in this together. | human papillomavirus-related cancers, which include cervical, vulvovaginal, anal, and oropharyngeal cancers, are on the rise in the united states. although the human papillomavirus vaccine has been on the market for 10 years, human papillomavirus vaccination rates are well below national goals. research identified many barriers and facilitators to human papillomavirus vaccination, and provider recommendation remains the most important factor in parental and patient decisions to vaccinate. while ... | 2017 | 28235464 |
| development and characterization of an hpv type-16 specific modified dna aptamer for the improvement of potency assays. | measuring vaccine potency is critical for vaccine release and is often accomplished using antibody-based elisas. antibodies can be associated with significant drawbacks that are often overlooked including lot-to-lot variability, problems with cell-line maintenance, limited stability, high cost, and long discovery lead times. here, we address many of these issues through the development of an aptamer, known as a slow off-rate modified dna aptamer (somamer), which targets a vaccine antigen in the ... | 2017 | 28233502 |
| knowledge and attitudes of women regarding gynaecological cancer prevention in an urban area of greece in financial crisis. | preventive gynaecological examinations (pges) are the main means of monitoring gynaecological cancers across the developed world. the purpose of this study was to investigate the perceptions and attitudes of women of a regional municipality of greece, regarding preventive gynaecological examinations amid economic crisis. | 2017 | 28233331 |
| relationship between human papilloma virus and subungual keratoacanthoma: two case reports and the outcomes of surgical treatment. | subungual keratoacanthoma (suka) is a rare form of keratoacanthoma, with the majority of the lesions appearing as rapidly growing, painful hyperkeratotic masses located under the distal nail plate of the thumb. in some cases, suka causes damage to the underlying bone. the first case presented here was treated by surgical excision alone, and human papilloma virus (hpv) type 6 was detected in the tissue samples. the second case was treated by surgical excision plus curettage; however, hpv was not ... | 2017 | 28232913 |
| response evaluation in head and neck oncology: definition and prediction. | curative treatment of head and neck squamous cell carcinoma includes surgery and/or (chemo)radiation, whereas in the palliative setting, chemotherapy and/or immunotherapy represent(s) the standard approach. with regard to quality control, methods for determining treatment response are sorely needed. for surgical therapy, histopathology is the standard quality control. established criteria for high-risk patients include resection margins of the primary tumor and extracapsular extension of lymph n ... | 2017 | 28231577 |
| corrigendum to "prevalence of human papillomavirus genotypes, and mucosal iga anti-viral responses in women with cervical ectopy" [j. clin. virol. 47 (2010) 43-48]. | 2017 | 28231562 | |
| exploring human papillomavirus vaccination refusal among ethnic minorities in england: a comparative qualitative study. | in england, uptake of human papillomavirus (hpv) vaccination to prevent hpv-related cancer is lower among girls from ethnic minority backgrounds. we aimed to explore the factors that prevented ethnic minority parents from vaccinating, compared to white british nonvaccinating parents and vaccinating ethnic minority parents. | 2017 | 28231418 |
| prevalence of hpv 16 and 18 and attitudes toward hpv vaccination trials in patients with cervical cancer in mali. | cervical cancer is one of the most common and lethal cancers in west africa. even though vaccines that protect against the most common human papillomavirus (hpv) strains, 16 and 18, are currently in use in developed countries, the implementation of these vaccines in developing countries has been painfully slow, considering the pre-eminence of hpv-associated cervical cancer among women in those countries. | 2017 | 28231334 |
| investigation of p16 status, chemotherapy regimen, and other nutrition markers for predicting gastrostomy in patients with head and neck cancer. | the purpose of this study was to determine if p16 status, chemotherapy regimen, or other nutrition markers could improve protocol accuracy in predicting proactive gastrostomy in patients with head and neck cancer. | 2017 | 28230929 |
| preliminary results of a screening program for anal cancer and its precursors for hiv-infected men who have sex with men in vigo-spain. | men who have sex with men (msm) infected with human immunodeficiency virus (hiv) have the highest risk of developing anal cancer (ac). the objective of this study was to describe our screening implementation program in this population, and report the prevalence of human papillomavirus (hpv) anal infection, and cytological and histological findings in a spanish medium-size community (vigo, spain). | 2017 | 28229612 |
| betel nut chewing, oral premalignant lesions, and the oral microbiome. | oral cancers are attributed to a number of causal agents including tobacco, alcohol, human papillomavirus (hpv), and areca (betel) nut. although betel nut chewing has been established as an independent cause of oral cancer, the mechanisms of carcinogenesis are poorly understood. an investigation was undertaken to evaluate the influence of betel nut chewing on the oral microbiome and oral premalignant lesions. study participants were recruited from a dental clinic in guam. structured interviews a ... | 2017 | 28225785 |
| immunostaining for high-risk human papillomavirus in condyloma lesions in immunocompromised patients. | human papillomavirus (hpv) is the underlying infectious cause of condyloma acuminata (ca) and high-risk types of hpv can cause cancer. condyloma may undergo malignant degeneration, particularly in immunosuppressed patients. the presence of high-risk hpv in ca is a risk factor for developing malignancy; however, determining which patients with condyloma are clinically at risk can be difficult. high-risk hpv can now be localized within ca using routine immunohistochemical stains. | 2017 | 28224503 |
| performance and diagnostic accuracy of a urine-based human papillomavirus assay in a referral population. | background hpv testing from clinician-collected cervical and self-collected cervico-vaginal samples is more sensitive for detecting cin2+/cin3+ than cytology-based screening, stimulating interest in hpv testing from urine. the objective was to determine the performance of the trovagene hpv test for the detection of cin2+ from urine and preservcyt cervical samples. methods women referred for colposcopy at st mary's hospital london, following abnormal cytology, were recruited to this diagnostic ac ... | 2017 | 28223432 |