Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
|---|
| prediction of hydration free energies for aliphatic and aromatic chloro derivatives using molecular dynamics simulations with the opls-aa force field. | all-atom molecular dynamics computer simulations were used to blindly predict the hydration free energies of a range of chloro-organic compounds as part of the sampl3 challenge. all compounds were parameterized within the framework of the opls-aa force field, using an established protocol to compute the absolute hydration free energy via a windowed free energy perturbation approach and thermodynamic integration. three different approaches to deriving partial charge parameters were pursued: (1) u ... | 2012 | 22187140 |
| effect of cationic polymers on foam rheological properties. | we study the effect of two cationic polymers, with trade names jaguar c13s and merquat 100, on the rheological properties of foams stabilized with a mixture of anionic and zwitterionic surfactants (sodium lauryloxyethylene sulfate and cocoamidopropyl betaine). a series of five cosurfactants are used to compare the effect of these polymers on foaming systems with high and low surface dilatational moduli. the experiments revealed that the addition of jaguar to the foaming solutions leads to (1) a ... | 2012 | 22168570 |
| mitogenomic analysis of the genus panthera. | the complete sequences of the mitochondrial dna genomes of panthera tigris, panthera pardus, and panthera uncia were determined using the polymerase chain reaction method. the lengths of the complete mitochondrial dna sequences of the three species were 16990, 16964, and 16773 bp, respectively. each of the three mitochondrial dna genomes included 13 protein-coding genes, 22 trna, two rrna, one o(l)r, and one control region. the structures of the genomes were highly similar to those of felis catu ... | 2011 | 22038004 |
| noninvasive monitoring of adrenocortical function in captive jaguars (panthera onca). | jaguars are threatened with extinction throughout their range. a sustainable captive population can serve as a hedge against extinction, but only if they are healthy and reproduce. understanding how jaguars respond to stressors may help improve the captive environment and enhance their wellbeing. thus, our objectives were to: (1) conduct an adrenocorticotrophic hormone (acth) challenge to validate a cortisol radioimmunoassay (ria) for noninvasive monitoring of adrenocortical function in jaguars; ... | 2012 | 21953790 |
| forensic scatology: preliminary experimental study of the preparation and potential for identification of captive carnivore scat. | carnivore scats recovered from animal attack and/or scavenging contexts frequently contain forensic evidence such as human bone fragments. forensic cases with carnivore involvement are increasingly prevalent, necessitating a methodology for the recovery and analysis of scat evidence. this study proposes a method for the safe preparation of carnivore scat, recovery of bone inclusions, and quantification and comparison of scat variables. fourteen scats (lion, jaguar, lynx, wolf, and coyote) were p ... | 2011 | 21923796 |
| standard gibbs free energies of reactions of ozone with free radicals in aqueous solution: quantum-chemical calculations. | free radicals are common intermediates in the chemistry of ozone in aqueous solution. their reactions with ozone have been probed by calculating the standard gibbs free energies of such reactions using density functional theory (jaguar 7.6 program). o(2) reacts fast and irreversibly only with simple carbon-centered radicals. in contrast, ozone also reacts irreversibly with conjugated carbon-centered radicals such as bisallylic (hydroxycylohexadienyl) radicals, with conjugated carbon/oxygen-cente ... | 2011 | 21910507 |
| tungiasis in a free-ranging jaguar (panthera onca) population in brazil. | tungiasis is an ectoparasitic disease caused by fleas of the genus tunga. the disease is reported to occur mostly in human populations. in wildlife, however, the occurrence and impact of this disease remains uncertain. we captured and examined 12 free-ranging jaguars for the presence of tunga penetrans in the pantanal region of mato grosso do sul state, brazil. tungiasis prevalence was 100% in the population; lesions were confined to the jaguar's paws. t. penetrans was identified based on the ch ... | 2011 | 21863398 |
| myosin vi contributes to synaptic transmission and development at the drosophila neuromuscular junction. | myosin vi, encoded by jaguar (jar) in drosophila melanogaster, is a unique member of the myosin superfamily of actin-based motor proteins. myosin vi is the only myosin known to move towards the minus or pointed ends of actin filaments. although myosin vi has been implicated in numerous cellular processes as both an anchor and a transporter, little is known about the role of myosin vi in the nervous system. we previously recovered jar in a screen for genes that modify neuromuscular junction (nmj) ... | 2011 | 21745401 |
| successful carnivore identification with faecal dna across a fragmented amazonian landscape. | the use of scat surveys to obtain dna has been well documented in temperate areas, where dna preservation may be more effective than in tropical forests. samples obtained in the tropics are often exposed to high humidity, warm temperatures, frequent rain and intense sunlight, all of which can rapidly degrade dna. despite these potential problems, we demonstrate successful mtdna amplification and sequencing for faeces of carnivores collected in tropical conditions and quantify how sample conditio ... | 2011 | 21676206 |
| tick-borne bacteria in free-living jaguars (panthera onca) in pantanal, brazil. | abstract tick-borne bacteria were investigated in 10 free-living jaguars and their ticks in the pantanal biome, brazil. jaguar sera were tested by indirect fluorescent antibody assays using rickettsia rickettsii, rickettsia parkeri, rickettsia amblyommii, rickettsia rhipicephali, rickettsia felis, rickettsia bellii, ehrlichia canis, and coxiella burnetii as crude antigens. all 10 jaguar sera reacted (titer ≥64) to at least one rickettsia species; 4 and 3 sera reacted with e. canis and c. burneti ... | 2011 | 21612532 |
| big cat phylogenies, consensus trees, and computational thinking. | abstract phylogenetics seeks to deduce the pattern of relatedness between organisms by using a phylogeny or evolutionary tree. for a given set of organisms or taxa, there may be many evolutionary trees depicting how these organisms evolved from a common ancestor. as a result, consensus trees are a popular approach for summarizing the shared evolutionary relationships in a group of trees. we examine these consensus techniques by studying how the pantherine lineage of cats (clouded leopard, jaguar ... | 2011 | 21563975 |
| serological detection of viral infections in captive wild cats from costa rica. | serum samples from a total of 44 wildcats, 28 margays (leopardus wiedii), 10 ocelots (leopardus pardalis), four jaguaroundis (herpailurus yaguaroundi), one oncilla (leopardus tigrina), and one jaguar (panthera onca) were obtained between january 2001 and august 2002 from the profelis centre for rehabilitation of wild felids, located in the northwestern region of costa rica. forty three samples were tested for antibodies against feline immunodeficiency virus (fiv) and p27 antigen of feline leukem ... | 2011 | 21547230 |
| genotyping of potentially zoonotic giardia duodenalis from exotic and wild animals kept in captivity in brazil. | we have studied the variability of glutamate dehydrogenase (gdh) and small subunit ribosomal (ssu) rrna coding genes of giardia species in fecal samples isolated from wild and exotic animals in brazil, and compared with homologous sequences of isolates from human and domestic animals characterized in previous studies. cysts of giardia duodenalis were obtained from feces of naturally infected monkeys (alouatta fusca) (n=20), chinchillas (chinchilla lanigera) (n=3), ostriches (struthio camelus) (n ... | 2011 | 21530084 |
| identification of neotropical felid faeces using rcp-pcr. | faeces similarity among sympatric felid species has generally hampered their use in distributional, demographic and dietary studies. here, we present a new and simple approach based on a set of species-specific primers, for the unambiguous identification of faeces from sympatric neotropical felids (i.e. puma, jaguar, jaguarundi and ocelot/ margay). this method, referred to as rapid classificatory protocol-pcr (rcp-pcr), consists of a single-tube multiplex pcr yielding species-specific banding pa ... | 2011 | 21429118 |
| attacks by jaguars (panthera onca) on humans in central brazil: report of three cases, with observation of a death. | conflicts between humans and big cats have been known for centuries throughout the world, but have intensified in recent decades. recently, attacks by panthera onca on humans in brazil have been brought to the forefront through exposure in the press and because of the severity of the attacks. we report 3 cases of patients attacked by jaguars in provoked and predatory situations. two patients survived the attacks and one died. attack mechanisms and lesions in victims are discussed. the attacks de ... | 2011 | 21396857 |
| dna extraction from hair shafts of wild brazilian felids and canids. | wild felids and canids are usually the main predators in the food chains where they dwell and are almost invisible to behavior and ecology researchers. due to their grooming behavior, they tend to swallow shed hair, which shows up in the feces. dna found in hair shafts can be used in molecular studies that can unravel, for instance, genetic variability, reproductive mode and family structure, and in some species, it is even possible to estimate migration and dispersion rates in given populations ... | 2010 | 21174262 |
| the effect of habitat fragmentation on the genetic structure of a top predator: loss of diversity and high differentiation among remnant populations of atlantic forest jaguars (panthera onca). | habitat fragmentation may disrupt original patterns of gene flow and lead to drift-induced differentiation among local population units. top predators such as the jaguar may be particularly susceptible to this effect, given their low population densities, leading to small effective sizes in local fragments. on the other hand, the jaguar's high dispersal capabilities and relatively long generation time might counteract this process, slowing the effect of drift on local populations over the time f ... | 2010 | 21040050 |
| effectiveness of scat-detection dogs in determining species presence in a tropical savanna landscape. | most protected areas are too small to sustain populations of wide-ranging mammals; thus, identification and conservation of high-quality habitat for those animals outside parks is often a high priority, particularly for regions where extensive land conversion is occurring. this is the case in the vicinity of emas national park, a small protected area in the brazilian cerrado. over the last 40 years the native vegetation surrounding the park has been converted to agriculture, but the region still ... | 2010 | 21029162 |
| renal lesions of nondomestic felids. | to comprehensively evaluate the occurrence of renal lesions in a variety of nondomestic felids, necropsy cases from 1978 to 2008 were reviewed from a municipal zoo and a large cat sanctuary for those in which the kidneys were examined histologically. seventy exotic felids were identified (25 tigers, 18 lions, 6 cougars, 5 leopards, 3 snow leopards, 3 clouded leopards, 3 canadian lynx, 2 ocelots, 2 bobcats, 2 cheetahs, 1 jaguar), and their histologic renal lesions were evaluated and compared. the ... | 2010 | 20876911 |
| the drosophila gipc homologue can modulate myosin based processes and planar cell polarity but is not essential for development. | epithelia often show, in addition to the ubiquitous apico-basal (a/b) axis, a polarization within the plane of the epithelium, perpendicular to the a/b axis. such planar cell polarity (pcp) is for example evident in the regular arrangement of the stereocilia in the cochlea of the mammalian inner ear or in (almost) all drosophila adult external structures. gipcs (gaip interacting protein, c terminus) were first identified in mammals and bind to the galphai gtpase activating protein rgs-gaip. they ... | 2010 | 20574526 |
| stochastic simulation of uranium migration at the hanford 300 area. | this work focuses on the quantification of groundwater flow and subsequent u(vi) transport uncertainty due to heterogeneity in the sediment permeability at the hanford 300 area. u(vi) migration at the site is simulated with multiple realizations of stochastically-generated high resolution permeability fields and comparisons are made of cumulative water and u(vi) flux to the columbia river. the massively parallel reactive flow and transport code pflotran is employed utilizing 40,960 processor cor ... | 2011 | 20510479 |
| supermatrix and species tree methods resolve phylogenetic relationships within the big cats, panthera (carnivora: felidae). | the pantherine lineage of cats diverged from the remainder of modern felidae less than 11 million years ago and consists of the five big cats of the genus panthera, the lion, tiger, jaguar, leopard, and snow leopard, as well as the closely related clouded leopard. a significant problem exists with respect to the precise phylogeny of these highly threatened great cats. despite multiple publications on the subject, no two molecular studies have reconstructed panthera with the same topology. these ... | 2010 | 20138224 |
| the role of landowners in jaguar conservation in sonora, mexico. | the northernmost known breeding population of jaguars occurs in the municipality of nácori chico, sonora, mexico about 270 km from the united states-mexico border and may be the source from which jaguars sighted in the united states dispersed. since 1999 at least 11 jaguars (panthera onca) had been illegally killed in the area due to predator control programs. we initiated a jaguar landowner-based conservation plan in 2004. the eight participating landowners agreed to suspend predator control pr ... | 2010 | 20136872 |
| comparison of nine programs predicting pk(a) values of pharmaceutical substances. | knowledge of the possible ionization states of a pharmaceutical substance, embodied in the pk(a) values (logarithm of the acid dissociation constant), is vital for understanding many properties essential to drug development. we compare nine commercially available or free programs for predicting ionization constants. eight of these programs are based on empirical methods: acd/pk(a) db 12.0, adme boxes 4.9, admet predictor 3.0, epik 1.6, marvin 5.1.4, pallas pkalc net 2.0, pipeline pilot 5.0, and ... | 2009 | 19961204 |
| detection of bartonella spp. in neotropical felids and evaluation of risk factors and hematological abnormalities associated with infection. | although antibodies to bartonella henselae have been described in all neotropical felid species, dna has been detected in only one species, leopardus wiedii. the aim of this study was to determine whether dna of bartonella spp. could be detected in blood of other captive neotropical felids and evaluate risk factors and hematological findings associated with infection. blood samples were collected from 57 small felids, including 1 leopardus geoffroyi, 17 l. wiedii, 22 leopardus tigrinus, 14 leopa ... | 2010 | 19913372 |
| evaluation of nutrient digestibility and fecal characteristics of exotic felids fed horse- or beef-based diets: use of the domestic cat as a model for exotic felids. | the objective of this study was to determine the effects of feeding commercially available beef- and horse-based diets on nutrient digestibility and fecal characteristics of large captive exotic felids and domestic cats. four species of large exotic felids including cheetahs, malayan tigers, jaguars, and amur tigers, and domestic cats were utilized in a crossover design. raw meat diets included a beef-based diet (57% protein; 28% fat) and a horse-based diet (51% protein; 30% fat). all cats were ... | 2010 | 19830746 |
| echinococcus oligarthrus cystic hydatidosis in brazilian agouti (dasyprocta leporina). | echinococcus oligarthrus hydatid cyst disease was diagnosed in two imported wild-caught brazilian agouti (dasyprocta leporina). the cysts were found incidentally during routine examinations and never appeared to cause any apparent clinical signs. identification of the cysts was confirmed via histopathology. over a period of 2 yr, the cysts calcified but did not reabsorb. treatment with praziquantal and albendazole did not appear to affect the cysts. agoutis are intermediate hosts of e. oligarthr ... | 2009 | 19746872 |
| ozonolysis of lignin models in aqueous solution: anisole, 1,2-dimethoxybenzene, 1,4-dimethoxybenzene, and 1,3,5-trimethoxybenzene. | the lignin models anisole, 1,2-dimethoxybenzene, 1,4-dimethoxybenzene, and 1,3,5-trimethoxybenzene were reacted with ozone in aqueous solution, and major products were identified and quantified with respect to ozone consumption when reference material was available. hydroxylation products in yields equivalent to those of singlet oxygen and muconic products (in analogy to the criegee mechanism) dominate. the formation of quinones points to the release of methanol. hydroxyl radicals (*oh, quantifi ... | 2009 | 19746725 |
| leishmania(leishmania) chagasi in captive wild felids in brazil. | this study used a pcr-rflp test to determine the presence of leishmania (leishmania) chagasi in 16 captive wild felids [seven puma concolor (linnaeus, 1771); five panthera onca (linnaeus, 1758) and four leopardus pardalis (linnaeus, 1758)] at the zoological park of the federal university of mato grosso, brazil. amplification of leishmania spp. dna was seen in samples from five pumas and one jaguar, and the species was characterized as l. chagasi using restriction enzymes. it is already known tha ... | 2010 | 19740501 |
| variance in the chemical composition of dry beans determined from uv spectral fingerprints. | nine varieties of dry beans representing five market classes were grown in three locations (maryland, michigan, and nebraska), and subsamples were collected for each variety (row composites from each plot). aqueous methanol extracts of ground beans were analyzed in triplicate by uv spectrophotometry. analysis of variance-principal component analysis was used to quantify the relative variance arising from location, variety, between rows of plants, and analytical uncertainty and to test the signif ... | 2009 | 19731933 |
| cell population indexes of spermatogenic yield and testicular sperm reserves in adult jaguars (panthera onca). | the intrinsic yield of spermatogenesis and supporting capacity of sertoli cells are the desirable indicators of sperm production in a species. the objective of the present study was to quantify intrinsic yield and the sertoli cell index in the spermatogenic process and estimate testicular sperm reserves by histological assessment of fragments obtained by testicular biopsy of five adult jaguars in captivity. the testicular fragments were fixed in 4% glutaric aldehyde, dehydrated at increasing alc ... | 2010 | 19564086 |
| [identification of individual jaguars (panthera onca) and pumas (puma concolor) based on footprint morphometry (carnivora: felidae)]. | estimating feline abundance becomes particularly difficult, sometimes impossible, due to their elusive behavior and extensive space requirements. available techniques are expensive and/or poorly efficient, therefore alternative methods are needed. the objective of this study was to assess the possibility of identifying individual jaguars and pumas based on morphometric analyses of their tracks. the footprints of five jaguars and four pumas were drawn and the foot (hind or fore foot, left or righ ... | 2008 | 19419090 |
| nutrient digestibility and fecal characteristics are different among captive exotic felids fed a beef-based raw diet. | nutrient digestibility has not been well characterized in exotic felids. the objective of this experiment was to evaluate differences in nutrient digestibility and fecal characteristics in five large exotic captive felid species, including bobcats, jaguars, cheetahs, indochinese tigers, and siberian tigers. all animals were individually housed and adapted to a beef-based raw diet (nebraska brand((r)) special beef feline, north platte, ne) for 16 d. total fecal collections were conducted from day ... | 2008 | 19360610 |
| comparison of several types of enrichment for captive felids. | enrichment can increase the complexity of the captive environment and possibly enhance captive animals' well-being by stimulating active behaviors and reducing stereotypical behaviors commonly seen in zoo felids. in this study, three different enrichment items were added to outdoor enclosures of felids at the montgomery zoo to test their effects on activity levels and stereotypic pacing. bones, frozen fish, and spices (cinnamon, chili powder, and cumin) were presented over a 3-month period to si ... | 2007 | 19360587 |
| first evidence of canine distemper in brazilian free-ranging felids. | serum samples from 19 jaguars (panthera onca), nine pumas (puma concolor), and two ocelots (leopardus pardalis) were collected between january 1999 and march of 2005 and tested for presence of canine distemper virus (cdv). all cats were free-ranging animals living in two protected areas in the brazilian atlantic forest. in addition, 111 domestic dogs from nearby areas were sampled for cdv. our results show the first evidence of cdv exposure in brazilian free-ranging felids. from the 30 samples a ... | 2009 | 19259737 |
| [felines: an alternative in genetic toxicology studies?]. | the micronuclei (mn) test carry out in peripheral blood is fast, simple, economic and it is used to detect genotoxic environmental agents. mn are fragments of chromosomes or complete chromosomes remaining in the cytoplasm after cell division, which increase when organisms are exposed to genotoxic agents. therefore, species with the highest values of spontaneous micronucleated erythrocytes (mne) are the most suitable to be potentials biomonitor of micronucleogenic agents, using a drop of blood. n ... | 2008 | 19256458 |
| molecular detection of cytauxzoon spp. in asymptomatic brazilian wild captive felids. | cytauxzoon spp. dna was detected for the first time in blood samples from asymptomatic brazilian wild captive felids. in 2006, 72 edta blood samples from seven wild felids species: puma concolor (puma), leopardus pardalis (ocelot), puma yagouaroundi (jaguarundi), leopardus wiedii (margay), leopardus tigrinus (little spotted cat), oncifelis colocolo (pampas cat) and panthera onca (jaguar) were analyzed using polymerase chain reaction to amplify the 18s rrna gene segment in order to verify the pre ... | 2009 | 19204356 |
| biodiversity of the pantanal: response to seasonal flooding regime and to environmental degradation. | seasonal flooding is the most important ecological phenomenon in the pantanal. every year many parts of the biome change from terrestrial into aquatic habitats and vice-versa. the degree of inundation creates a range of major habitats. flooding occupies about 80% of the whole pantanal. in contrast, during the dry season, most of the flooded areas stay dry, when the water returns to the river beds or evaporates. the pantanal is a large continental savanna wetland (147,574 km(2) in brazil), touchi ... | 2008 | 19197468 |
| development and testing of an optimized method for dna-based identification of jaguar (panthera onca) and puma (puma concolor) faecal samples for use in ecological and genetic studies. | the elusive nature and endangered status of most carnivore species imply that efficient approaches for their non-invasive sampling are required to allow for genetic and ecological studies. faecal samples are a major potential source of information, and reliable approaches are needed to foster their application in this field, particularly in areas where few studies have been conducted. a major obstacle to the reliable use of faecal samples is their uncertain species-level identification in the fi ... | 2009 | 19137401 |
| neoplasia in felids at the knoxville zoological gardens, 1979-2003. | a review of medical records and necropsy reports from 1979-2003 found 40 neoplasms in 26 zoo felids, including five lions (panthera leo, two males and three females), three leopards (panthera pardus, two males and one female), one jaguar (panthera onca, female), 11 tigers (panthera tigris, three males and eight females), two snow leopards (panthera uncia, one male and one female), two cougars (felis concolor, one male and one female), one bobcat (felis rufus, male), and one cheetah (acinonyx jub ... | 2008 | 19110704 |
| duration of spermatogenesis and daily sperm production in the jaguar (panthera onca). | the jaguar, like most wild felids, is an endangered species. since there are few data regarding reproductive biology for this species, our main goal was to investigate basic aspects of the testis and spermatogenesis. four adult male jaguars were utilized; to determine the duration of spermatogenesis, two animals received an intratesticular injection of h(3)-thymidine. mean (+/-sem) testis weight and the gonadosomatic index were 17.7+/-2.2g and 0.05+/-0.01%, respectively, whereas the seminiferous ... | 2008 | 18672284 |
| "may the force be with you": 14th samuel haughton lecture. | this paper presents the 14th samuel haughton lecture delivered on the 26th of january 2008. the lecture began by describing haughton's research on animal mechanics. haughton opposed charles darwin's theory of natural selection using the argument that the skeleton obeys the 'principle of least action' and therefore must have been designed with that principle in mind. in the course of his research he dissected many animals, including albatrosses, cassowaries, llamas, tigers, jackals and jaguars. h ... | 2008 | 18641919 |
| seroepidemiology of toxoplasma gondii in zoo animals in selected zoos in the midwestern united states. | toxoplasma gondii infections in zoo animals are of interest because many captive animals die of clinical toxoplasmosis and because of the potential risk of exposure of children and elderly to t. gondii oocysts excreted by cats in the zoos. seroprevalence of t. gondii antibodies in wild zoo felids, highly susceptible zoo species, and feral cats from 8 zoos of the midwestern united states was determined by using the modified agglutination test (mat). a titer of 1:25 was considered indicative of t. ... | 2008 | 18605803 |
| organization and quantification of the elements in the intertubular space in the adult jaguar testis (panthera onca, linnaeus, 1758). | the endocrine portion of mammal testicle is represented by leydig cells which, together with connective cells, leukocytes, blood and lymphatic vessels, form the intertubular space. the arrangement and proportion of these components vary in the different species of mammals and form mechanisms that keep the testosterone level--the main product of the leydig cell--two to three times higher in the interstitial fluid than in the testicular blood vessels and 40-250 times higher in these than in the pe ... | 2008 | 18602267 |
| captive-born cotton-top tamarins (saguinus oedipus) respond similarly to vocalizations of predators and sympatric nonpredators. | what types of cues do callitrichid primates use to detect and respond to predators? do they respond to predator-specific cues or to more general cues? the evidence for these questions remains conflicting. we presented captive-born and reared cotton-top tamarins with no previous exposure to predators (or predator cues) with vocalizations from three potential predators of cotton-top tamarin in the wild (white hawk, jaguar, and tayra) and with vocalizations from sympatric nonpredators (black-faced ... | 2008 | 18473378 |
| [citogenetic characterization of the tropical freshwater fish parachromis managuensis (pisces: cichlidae)]. | to describe the cytogenetics of the jaguar cichlid fish parachromis managuensis, we collected eight males and 13 females in villahermosa, tabasco, méxico. the specimens were processed with standard cytogenetic techniques (slightly modified), and high quality fields of chromosomes in mitosis and meiosis were obtained; 14 of these fields were analyzed by meristics and statistics methods. the specimens presented a diploid modal number of 2n = 48 chromosomes, which is similar to the number reported ... | 2006 | 18457172 |
| atypical toxoplasma gondii strain from a free-living jaguar (panthera onca) in french guiana. | like domestic cats, wild felids are involved in the complete infective cycle of toxoplasma gondii because they can host in their gastrointestinal tract sexually mature parasites and shed infective oocysts in their feces. we report, to our knowledge, the first isolation and molecular characterization of a t. gondii strain from the heart tissue of a free-living jaguar (panthera onca) in french guiana. sequencing at six polymorphic markers indicated that the jaguar isolate had an atypical genotype, ... | 2008 | 18256411 |
| we recently received a 27-year-old female zoo worker who was attacked by a jaguar (panthera onca) while cleaning its cage.. | 2007 | 18073627 | |
| comparative pathology of mammary gland cancers in domestic and wild animals. | mammary cancer occurs among all taxonomic groups, and comparing the disease in animals with breast cancer in women could greatly improve our understanding of the relevant risk factors and genetic profiles for this disease. differences in cancer prevalence between carnivores and herbivores and between captive and wild carnivores are striking and support the hypotheses that diet and reproductive history are major risk factors. domestic dogs and cats have a high prevalence of mammary tumors, and th ... | 2007 | 18057539 |
| improved interpretation of genotypic changes in the hiv-1 reverse transcriptase coding region that determine the virological response to didanosine. | consensus on the interpretation of mutations in the human immunodeficiency virus (hiv)-1 reverse transcriptase (rt) gene that predict the response to didanosine treatment is needed. | 2007 | 18008248 |
| cell adhesion molecule echinoid associates with unconventional myosin vi/jaguar motor to regulate cell morphology during dorsal closure in drosophila. | echinoid (ed) is a homophilic immunoglobulin domain-containing cell adhesion molecule (cam) that localizes to adherens junctions (ajs) and cooperates with drosophila melanogaster epithelial (de)-cadherin to mediate cell adhesion. here we show that ed takes part in many processes of dorsal closure, a morphogenetic movement driven by coordinated cell shape changes and migration of epidermal cells to cover the underlying amnioserosa. ed is differentially expressed, appearing in epidermis but not in ... | 2007 | 17936269 |
| characterization of cauxin in the urine of domestic and big cats. | cauxin is an abundant protein in feline urine. we have used proteomics strategies to characterize cauxin from the urine of domestic cats and a number of big cat species. proteins were resolved by gel-based electrophoretic purification and subjected to in-gel digestion with trypsin. the resultant tryptic peptides were mass-measured by matrix-assisted laser desorption ionization time of flight mass spectrometry. peptides were also resolved by liquid chromatography and analyzed by electrospray ioni ... | 2007 | 17924168 |
| jaguar medicine. | 2010 | 17900037 | |
| paleotemperatures and chronology at archeological cave site revealed by thermoluminescence. | contrasting values of remnant thermoluminescence of limestone samples from jaguar cave, eastcentral idaho, reveal temperature differences attributable to position within the cave microenvironment. absence of recorded temperature change during cave-filling by rock and human debris indicates brevity of human occupation, which was near the end of wisconsin (pine-dale) time. | 1965 | 17842752 |
| new high-charge density hydrophobically modified cationic hec polymers for improved co-deposition of benefit agents and serious conditioning for problem hair. | a series of new high charge density polyquaternium-67(1) (pq-67) polymers have been prepared and evaluated in shampoo formulations. these new compositions represent an addition to the family of high-viscosity quaternized hydroxyethylcellulose (hec) polymers with cationic substitution of trimethyl ammonium and dimethyldodecyl ammonium(2) (figure 1a) described in (1) and (2). the evaluation protocol included objective lab methods and subjective panel studies on different hair types. commercial con ... | 2010 | 17728943 |
| functional diversification of kir7.1 in cichlids accelerated by gene duplication. | mutation in the inward rectifier potassium channel gene, kir7.1, was previously identified as being responsible for the broader stripe zebrafish skin pattern mutant, jaguar/obelix. an amino acid substitution in this channel causes a broader stripe pattern than that of wild type zebrafish. in this study we analyzed cichlid homologs of the zebrafish kir7.1 gene. we identified two kinds of homologous genes in cichlids and named them cikir7.1 and cikir7.2. southern hybridization using cichlid genome ... | 2007 | 17553638 |
| measurement of thyroid hormones (thyroxine, t4; triiodothyronine, t3) in captive nondomestic felids. | the aim of this research was to obtain basic values for the evaluation of thyroid function in nondomestic felids. serum thyroid hormone concentrations (thyroxine, t4; triiodothyronine, t3) were measured by radioimmunoassay in 145 cats, representing nine species of captive nondomestic felids: jaguar (panthera onca), n = 49; puma (puma concolor), n = 10; ocelot (leopardus pardalis), n = 22; oncilla (leopardus tigrinus), n = 12; geoffroy (oncifelis geoffroyi), n = 4; jaguarundi (herpailurus yaguaro ... | 2007 | 17469287 |
| predation of wild spider monkeys at la macarena, colombia. | the killing of an adult male spider monkey (ateles belzebuth ) by a jaguar (panthera onca) and a predation attempt by a puma (felis concolor) on an adult female spider monkey have been observed at the ciem (centro de investigaciones ecológicas la macarena), la macarena, colombia. these incidents occurred directly in front of an observer, even though it is said that predation under direct observation on any type of primate rarely occurs. on the basis of a review of the literature, and the observa ... | 2008 | 17342352 |
| disseminated coccidioidomycosis in a captive indochinese tiger (panthera tigris corbetti) with chronic renal disease. | a 19-yr-old, 78.2-kg captive female indochinese tiger (panthera tigris corbetti) from the el paso zoo (el paso, texas, usa) with chronic renal disease was euthanized after a 10-day course of anorexia, depression, progressive rear limb weakness, muscle fasciculations, and head tremors. postmortem findings included pericardial effusion, generalized lymphadenopathy, glomerulosclerosis, glomerular atrophy with membranous glomerulonephropathy, and pancreatic adenocarcinoma. pyogranulomatous pneumonia ... | 2006 | 17315442 |
| neutralizing antibodies against feline herpesvirus type 1 in captive wild felids of brazil. | feline herpesvirus type 1 infection affects domestic cats, causing mainly upper respiratory tract diseases. although this infection has been described in captive and free-ranging wild felids from europe, asia, north america, and africa, no information is available on its occurrence among wild felids of brazil. in this study, 250 serum samples of six species of brazilian captive wild felids (leopardus tigrinus, leopardus wiedii, herpailurus yaguarondi, puma concolor, leopardus pardalis, and panth ... | 2005 | 17312763 |
| impact of hiv-1 reverse transcriptase polymorphism at codons 211 and 228 on virological response to didanosine. | to determine the potential impact of reverse transcriptase (rt) mutations, other than those currently known to confer nucleoside reverse transcriptase inhibitors (nrtis) resistance, on the virological response to didanosine (ddl). | 2006 | 17310813 |
| phenotypic susceptibility to didanosine is associated with antiviral activity in treatment-experienced patients with hiv-1 infection. | we investigated the relationship between human immunodeficiency virus (hiv) phenotypic susceptibility to didanosine and the antiviral activity of didanosine (ddi) in the jaguar study. | 2007 | 17205478 |
| [toxoplasmosis in french guiana. atypical (neo-)tropical features of a cosmopolitan parasitosis]. | toxoplasmosis, a typical cosmopolitan parasitosis, is a major health problem in french guiana. three factors account for this situation, i.e., (1) severity of toxoplasmosis in patients with hiv infection that is particularly prevalent in the area, (2) high risk of congenital transmission as shown by the steadily increasing prevalence of seropositivity in function of age in most of the guianese population and (3) recent identification of severe primary toxoplasmosis infection in immunocompetent p ... | 2006 | 17201300 |
| the expression pattern and cellular localisation of myosin vi during the drosophila melanogaster life cycle. | myosin vi is a motor protein which is necessary for the morphogenesis of epithelial tissues during drosophila development. the spatial and temporal expression of myosin vi was examined by expressing a gfp (green fluorescent protein) tagged myosin vi molecule (pgm), under the control of a myosin vi-gal4 line. pgm was present in tissues that were shown previously to express myosin vi, such as the ovarian follicle epithelium, and the individualization complex; and in other tissues, including the tr ... | 2007 | 17185045 |
| the re-emergence of felid camouflage with the decay of predator recognition in deer under relaxed selection. | when a previously common predator disappears owing to local extinction, the strong source of natural selection on prey to visually recognize that predator becomes relaxed. at present, we do not know the extent to which recognition of a specific predator is generalized to similar looking predators or how a specific predator-recognition cue, such as coat pattern, degrades under prolonged relaxed selection. using predator models, we show that deer exhibit a more rapid and stronger antipredator resp ... | 2007 | 17148247 |
| molecular evidence for species-level distinctions in clouded leopards. | among the 37 living species of felidae, the clouded leopard (neofelis nebulosa) is generally classified as a monotypic genus basal to the panthera lineage of great cats. this secretive, mid-sized (16-23 kg) carnivore, now severely endangered, is traditionally subdivided into four southeast asian subspecies (figure 1a). we used molecular genetic methods to re-evaluate subspecies partitions and to quantify patterns of population genetic variation among 109 clouded leopards of known geographic orig ... | 2006 | 17141620 |
| risk factors associated with sero-positivity to toxoplasma gondii in captive neotropical felids from brazil. | from september 1995 to february 2001, blood samples were collected from 865 neotropical felids belonging to 8 different species. these animals were housed in 86 institutions located in 78 cities of 20 brazilian states. our goal was to identify the risk factors associated with sero-positivity to toxoplasma gondii in captive neotropical felids from brazil. all serum samples were tested by the modified agglutination test (mat), using formalin-fixed whole tachyzoites and mercaptoethanol. for each an ... | 2007 | 17140683 |
| pigment pattern in jaguar/obelix zebrafish is caused by a kir7.1 mutation: implications for the regulation of melanosome movement. | many animals have a variety of pigment patterns, even within a species, and these patterns may be one of the driving forces of speciation. recent molecular genetic studies on zebrafish have revealed that interaction among pigment cells plays a key role in pattern formation, but the mechanism of pattern formation is unclear. the zebrafish jaguar/obelix mutant has broader stripes than wild-type fish. in this mutant, the development of pigment cells is normal but their distribution is altered, maki ... | 2006 | 17121467 |
| fmla-serious health condition. perry v. jaguar of troy. | 2006 | 17039822 | |
| two-stage turing model for generating pigment patterns on the leopard and the jaguar. | based on the results of phylogenetic analysis, which showed that flecks are the primitive pattern of the felid family and all other patterns including rosettes and blotches develop from it, we construct a turing reaction-diffusion model which generates spot patterns initially. starting from this spotted pattern, we successfully generate patterns of adult leopards and jaguars by tuning parameters of the model in the subsequent phase of patterning. | 2006 | 16907134 |
| a theoretical proposal for the synthesis of carbapenems from 4-(2-propynyl)azetidinones promoted by [w(co)5] as an alternative to the ag+-assisted process. | the synthesis of carbapenems from 4-(2-propynyl)azetidinones assisted by both ag+ and [w(co)5] was theoretically investigated by using the b3lyp/6-31+g(d)-lanl2dz level, taking into account the effect of solvent by the pb-scrf model implemented in jaguar. according to our results, the silver-assisted cyclization is a concerted process for which the low yield experimentally observed could mainly stem from the alkaline hydrolysis of the beta-lactam ring. this process is very efficiently catalyzed ... | 2006 | 16871499 |
| isolation of malassezia spp. from cerumen of wild felids. | the objective of this study was to determine the presence of different species of the genus malassezia in the healthy external auditory canal of wild felids maintained in captivity. one hundred and thirty-two adult animals (264 samples of cerumen), 77 males (58.3%) and 55 females (41.7%), were studied: large felids (55 animals) - 26 lions (panthera leo), 13 tigers (panthera tigris), 6 leopards (panthera pardus), 6 jaguars (panthera onca), 2 cheetahs (acinonyx jubatus), 2 pumas (puma concolor); s ... | 2006 | 16772235 |
| dna microsatellite characterization of the jaguar (panthera onca) in colombia. | the colombian jaguar population is thought to contain two different subspecies, panthera onca centralis and panthera onca onca. the genetic structure of this population was evaluated using 12 microsatellite loci (n = 62 samples). in addition, 22 jaguar dna samples from guatemala, paraguay, perú, bolivia, venezuela and brazil were analyzed for these microsatellite loci (n = 84 samples). the results of this study indicate six primary themes. first, the levels of gene diversity were very high. seco ... | 2006 | 16755135 |
| antibodies to west nile virus in asymptomatic mammals, birds, and reptiles in the yucatan peninsula of mexico. | surveillance for evidence of west nile virus (wnv) infection in taxonomically diverse vertebrates was conducted in the yucatan peninsula of mexico in 2003 and 2004. sera from 144 horses on cozumel island, quintana roo state, 415 vertebrates (257 birds, 52 mammals, and 106 reptiles) belonging to 61 species from the merida zoo, yucatan state, and 7 farmed crocodiles in ciudad del carmen, campeche state were assayed for antibodies to flaviviruses. ninety (62%) horses on cozumel island had epitope-b ... | 2006 | 16687701 |
| ectoparasites of free-ranging pumas and jaguars in the paraguayan chaco. | ectoparasites were collected from seven puma (puma concolor) and seven jaguar (panthera onca) live-captures (each representing six different animals) in the paraguayan chaco from 2002 to 2004. the same five species of ectoparasites were recovered from both host species: the flea, pulex simulans (total on both hosts combined=30 male, 49 female), and the ticks, amblyomma cajennense (1 male, 4 female, 46 nymphs, 241 larvae), amblyomma parvum (42 male, 25 female), amblyomma tigrinum (1 male, 7 femal ... | 2006 | 16464533 |
| the effects of visitor density and intensity on the behavior of two captive jaguars (panthera onca). | several researchers have reported significant effects of visitor density and intensity on captive animal behavior. this study determined whether this was the case for 2 captive jaguars housed at the woodland park zoo, seattle, wa. subjects were monitored for changes in behavior as a function of visitor density and intensity. the jaguars were observed for 8 hr per week for 29 weeks--march 31 until october 11, 1998--for a total of 230 hr. continuous frequency sampling was used, and visitor density ... | 2005 | 16436028 |
| robust segmentation and analysis of dna microarray spots using an adaptative split and merge algorithm. | microarray images push to their limits classical analysis methods, since gene spots are often poorly contrasted, ill defined and of irregular shapes. these characteristics hinder a robust quantification of corresponding values for red and green intensities as well as their r/g ratio. new approaches are thus needed to ensure accurate data extraction from these images. herein we present an automatic non-supervised algorithm for a fast and accurate spot data extraction from dna microarrays. the met ... | 2006 | 16423425 |
| evolutionary analysis of a large mtdna translocation (numt) into the nuclear genome of the panthera genus species. | translocation of cymtdna into the nuclear genome, also referred to as numt, has been reported in many species, including several closely related to the domestic cat (felis catus). we describe the recent transposition of 12,536 bp of the 17 kb mitochondrial genome into the nucleus of the common ancestor of the five panthera genus species: tiger, p. tigris; snow leopard, p. uncia; jaguar, p. onca; leopard, p. pardus; and lion, p. leo. this nuclear integration, representing 74% of the mitochondrial ... | 2006 | 16380222 |
| body size of smilodon (mammalia: felidae). | the body masses of the three large saber-toothed machairodontines, smilodon gracilis, s. fatalis, and s. populator, were estimated on the basis of 36 osteological variables from the appendicular skeleton of extant felids. a new model is introduced that takes the reliability of the predictor equations into account, since mass estimates are more reliable when computed from multiple variables per bone. at a body mass range of 55-100 kg, s. gracilis was comparable in size to extant jaguars, and s. f ... | 2005 | 16235255 |
| structure and patterns of sequence variation in the mitochondrial dna control region of the great cats. | mitochondrial dna control region structure and variation were determined in the five species of the genus panthera. comparative analyses revealed two hypervariable segments, a central conserved region, and the occurrence of size and sequence heteroplasmy. as observed in the domestic cat, but not commonly seen in other animals, two repetitive sequence arrays (rs-2 with an 80-bp motif and rs-3 with a 6-10-bp motif) were identified. the 3' ends of rs-2 and rs-3 were highly conserved among species, ... | 2001 | 16120284 |
| ticks (acari: ixodida) on wild carnivores in brazil. | the present study reports field data of ticks infesting wild carnivores captured from july 1998 to september 2004 in brazil. additional data were obtained from one tick collection and from previous published data of ticks on carnivores in brazil. during field work, a total of 3437 ticks were collected from 89 cerdocyon thous (crab-eating fox), 58 chrysocyon brachyurus (maned wolf), 30 puma concolor (puma), 26 panthera onca (jaguar), 12 procyon cancrivorus (crab-eating raccoon), 4 speothos venati ... | 2005 | 16082932 |
| comparison of tests and procedures to build clinically relevant genotypic scores: application to the jaguar study. | to compare non-parametric tests and procedures of selection in building clinically validated genotypic scores. | 2005 | 16038473 |
| seroprevalence and genomic divergence of circulating strains of feline immunodeficiency virus among felidae and hyaenidae species. | feline immunodeficiency virus (fiv) infects numerous wild and domestic feline species and is closely related to human immunodeficiency virus (hiv) and simian immunodeficiency virus (siv). species-specific strains of fiv have been described for domestic cat (felis catus), puma (puma concolor), lion (panthera leo), leopard (panthera pardus), and pallas' cat (otocolobus manul). here, we employ a three-antigen western blot screening (domestic cat, puma, and lion fiv antigens) and pcr analysis to sur ... | 2005 | 15956574 |
| evaluation of computational chemistry methods: crystallographic and cheminformatics analysis of aminothiazole methoximes. | cheminformatics is used to validate the capabilities of widely used quantum chemistry and molecular mechanics methods. among the quantum methods examined are the semiempirical mndo, am1, and pm3 methods, hartree-fock (ab initio) at a range of basis set levels, density functional theory (dft) at a range of basis sets, and a post-hartree-fock method, local moller-plesset second-order perturbation theory (lmp2). among the force fields compared are amber, mmff94, mmff94s, opls/a, opls-aa, sybyl, and ... | 2005 | 15921449 |
| clinically relevant genotype interpretation of resistance to didanosine. | we analyzed the didanosine (ddi) arm of the randomized, placebo-controlled jaguar trial in order to define a genotypic score for ddi associated with virologic response. in this arm, 111 patients experiencing virologic failure received ddi in addition to their current combination therapy for 4 weeks. the impact of mutations in the reverse transcriptase gene on the virologic response to ddi was studied in univariate analysis. genotypic score was constructed using step-by-step analyses first includ ... | 2005 | 15855490 |
| effects of low-level hydrophobic substitution on conditioning properties of cationic cellulosic polymers in shampoo systems. | a new class of cationic conditioning polymers (polymer sl) has been prepared and evaluated in shampoo formulations. polymer sl is a family of high viscosity quaternized hydroxyethyl cellulose (hec) polymers with cationic substitution of trimethyl ammonium and dimethyldodecyl ammonium (figure 1). sl compositions benefit from hydrophobic character to deliver superior conditioning performance in hair care applications. at the same time, low levels of hydrophobes have been chosen to assure good comp ... | 2004 | 15645097 |
| granulomatous pneumonia caused by pythium insidiosum in a central american jaguar, panthera onca. | a 7-month-old, male jaguar presented with dyspnea and leukocytosis unresponsive to antibiotic therapy. radiographs revealed unilateral pulmonary consolidation. an exploratory thoracotomy was performed, and the left lung, which contained a large multilobular mass with extensive fibrosis and numerous caseonecrotic foci, was removed. microscopically, eosinophilic granulomatous inflammation surrounded broad (4.4-8.3 microm) rarely septate hyphae. a diagnosis of pythium insidiosum infection was confi ... | 2004 | 15586573 |
| electrospray ionization ion-trap multistage mass spectrometric study of sodium cationized aldobiuronic and pseudoaldobiuronic acid derivatives. | fragmentation mechanisms of electrospray ionization (esi) mass spectrometry of aldobiuronic and pseudoaldobiuronic acid derivatives were elucidated by multistage mass spectrometric (ms(n), n = 2-5) measurements of selected ions. characteristic under the conditions of esi-ms analysis is the production of alkali metal (na and k) cationized adducts. the probability the of locations of na cations in per-o-methylated compounds was proved by quantum chemical calculations, using the jaguar program. the ... | 2004 | 15578757 |
| changes in the fecal concentrations of cortisol and androgen metabolites in captive male jaguars (panthera onca) in response to stress. | in the present study we determined the efficacy of the measurement of fecal cortisol and androgen metabolite concentrations to monitor adrenal and testicular activity in the jaguar (panthera onca). three captive male jaguars were chemically restrained and electroejaculated once or twice within a period of two months. fecal samples were collected daily for 5 days before and 5 days after the procedure and stored at -20 degrees c until extraction. variations in the concentrations of cortisol and an ... | 2004 | 15558198 |
| grafting raises the salt tolerance of tomato through limiting the transport of sodium and chloride to the shoot. | with the aim of determining whether grafting could improve salinity tolerance of tomato (lycopersicon esculentum mill.), and what characteristics of the rootstock were required to increase the salt tolerance of the shoot, a commercial tomato hybrid (cv. jaguar) was grafted onto the roots of several tomato genotypes with different potentials to exclude saline ions. the rootstock effect was assessed by growing plants at different nacl concentrations (0, 25, 50, and 75 mm nacl) under greenhouse con ... | 2005 | 15557292 |
| effects of porcine zona pellucida immunocontraceptives in zoo felids. | methods of contraception are necessary for management of zoo felids; however, the most commonly used contraceptive (melengestrol acetate implant) is associated with serious adverse reactions with long-term use. porcine zona pellucida (pzp) vaccines are promising as contraceptives, but their safety in zoo felids has not been tested. pzp vaccine was administered to 27 female felids representing 10 species, including african lion (panthera leo), asian leopard (p. pardus), jaguar (p. onca), tiger (p ... | 2004 | 15526881 |
| international training programs in reproductive sciences for conservation of latin american felids. | survival of the ten non-domestic felid species endemic to latin america is imperiled by habitat loss, poaching and poor captive management. over the past 10 years, conservation of these felids has been the primary focus of a reproductive research and training program conducted in brazil, mexico, and the usa. the objectives of this program were to: (1) provide intensive training in reproductive sciences to latin american scientists, (2) conduct collaborative studies investigating basic and applie ... | 2004 | 15271441 |
| seasonal variation in the endocrine-testicular function of captive jaguars (panthera onca). | captive adult male jaguars (panthera onca) from two locations in southeast brazil were studied to evaluate the effects of season on endocrine and testicular function. for assessment of testicular steroidogenic activity, androgen metabolite concentrations were measured in fecal samples collected one to three times per week over 14 ( n=14 ), 9 ( n=1 ) or 7 months ( n=1 ). to assess seasonality, data were grouped by season (summer: december-february; autumn: march-may; winter: june-august; spring: ... | 2004 | 15036961 |
| anagram: protein function assignment. | anagram is a web service for protein function assignment based on identity detection of small significant fragments (protomotifs) that can act as modular pieces in peptide construction. the system is able to assign function by finding correlations between protomotifs and functional annotations contained in swiss-prot and medline databases. in addition, function ontologies are used for hierarchical organization of the predicted functions. extensive tests have been carried out to evaluate the accu ... | 2004 | 14734328 |
| flocculation in mixtures of cationic polyelectrolytes and anionic surfactants. | the phase behavior of mixtures of a cationic polyelectrolyte ('jaguar') and an anionic surfactant (either sodium dodecyl sulfate or sodium lauryl ether sulfate) has been studied. for a given polyelectrolyte (and added nacl) concentration, with increasing surfactant concentration, three phase regions were identified. the first region is a single homogeneous phase. within this region, at some surfactant concentration, above the critical aggregation concentration, stable open-network 'particles' fo ... | 2003 | 14672840 |
| columbus dentist crowns jaguar. | 1965 | 14283458 | |
| identification of haemobartonella felis (mycoplasma haemofelis) in captive nondomestic cats. | this study was undertaken to determine whether haemobartonella felis (mycoplasma haemofelis), the causative bacterial agent of feline infectious anemia, infects nondomestic cats. routine complete blood count and polymerase chain reaction (pcr) were performed to detect the gene for 16s ribosomal rna for the organism. sixty-four blood samples were collected from 54 nondomestic cats, including tigers (panthera tigris), cheetahs (acinonyx jubatus), lions (p. leo), mountain lions (felis concolor), sn ... | 2003 | 12885130 |
| visceral mast cell tumor in a captive black jaguar (panthera onca). | little is known about neoplasia in the jaguar (panthera onca), the largest american feline. a captive black jaguar was diagnosed at necropsy with a mastocytic form of visceral mast cell tumor similar to that which occurs in domestic cats. this animal had no previous clinical disease and died during anesthesia for a routine dental treatment. | 2003 | 12723809 |
| asymmetric cell division: miranda chauffeured by jaguar? | drosophila neuroblasts divide to produce daughters of distinct fate by asymmetrically localizing cell fate determinants and segregating them preferentially to one daughter. an intact f-actin cytoskeleton was known to be required, and now a myosin vi (jaguar) has been shown to be necessary for basal targeting of cell fate determinants in neuroblasts. | 2003 | 12620217 |
| molecular genetics and evolution of melanism in the cat family. | melanistic coat coloration occurs as a common polymorphism in 11 of 37 felid species and reaches high population frequency in some cases but never achieves complete fixation. to investigate the genetic basis, adaptive significance, and evolutionary history of melanistic variants in the felidae, we mapped, cloned, and sequenced the cat homologs of two putative candidate genes for melanism (asip [agouti] and mc1r) and identified three independent deletions associated with dark coloration in three ... | 2003 | 12620197 |