Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
|---|
| prevalence and intensity of non-strongyle intestinal parasites of horses in northern queensland. | a quantitative post-mortem study of 57 horses from northern queensland was done to determine the prevalence and intensity of non-strongyle intestinal parasites. the following species (% prevalence) were found: draschia megastoma (39%); habronema muscae (43%); gasterophilus intestinalis (34%), g. nasalis (30%); parascaris equorum (15%); strongyloides westeri (6%); probstmayria vivipara (2%); oxyuris equi (26%); anoplocephala magna (2%); a. perfoliata (32%). mean parasite numbers of individual spe ... | 1989 | 2930389 |
| efficacy of ivermectin in oral drench and paste formulation against migrating larvae of experimentally inoculated parascaris equorum. | twenty-one mixed-breed pony foals, reared and maintained under parasite-free conditions, were used to test the efficacy of ivermectin in oral drench and paste formulations (200 micrograms/kg) against 11-day-old migrating larvae of parascaris equorum. three replicates of 4 foals and 3 replicates of 3 foals were formed on the basis of age. foals in replicates of 4 were randomly allocated to be indicators, or to receive vehicle (control) or ivermectin paste or ivermectin liquid. foals in replicates ... | 1989 | 2774327 |
| unusual kinetochores and chromatin diminution in parascaris. | the first description of the cytogenetics of the horse parasitic nematode ascaris megalocephala (parascaris equorum) represented an important step in the history of genetics. the chromosomes of this organism possess a particular centromeric organization and undergo a process known as chromatin diminution in all presomatic cells during early development. both these unusual features make parascaris a good model to study general aspects of chromosome biology. | 1989 | 2686123 |
| controlled test and clinical evaluation of dienbendazole against naturally acquired gastrointestinal parasites in ponies. | a controlled test was performed to titrate the anthelmintic dosage of dienbendazole in 24 mixed-breed ponies naturally infected with strongylus vulgaris, s edentatus, and small strongyle species, as determined by parasitic egg and larval counts in feces. comparison of results of treatment was made among 3 dienbendazole dosages--2.5, 5, and 10 mg/kg of body weight--and a gum (excipient) mixture given by nasogastric intubation. all ponies were euthanatized and necropsied at 7 or 8 days after treat ... | 1989 | 2619127 |
| efficacy of ivermectin in the treatment of induced parascaris equorum infection in pony foals. | eighteen pony foals inoculated with 1,500 +/- 109 infective parascaris equorum eggs were given 0.02 ml of ivermectin vehicle (liquid)/kg of body weight, po, (control); 0.2 mg of ivermectin paste/kg, po; or 0.2 mg ivermectin liquid/kg, po, on postinoculation day (pid) 28. foals were euthanatized on pid 42, and the small intestinal contents were examined for p equorum larvae. the mean number of fourth-stage p equorum larvae in foals treated with ivermectin paste and liquid were 3.5 and 6, respecti ... | 1989 | 2599956 |
| critical and controlled tests of activity of a macrocyclic lactone (compound f28249-alpha) against natural infections in internal parasites of equids. | thirteen critical tests (n = 11 horses and 2 ponies) and 4 controlled tests (n = 4 donkeys and 6 horses) were performed to evaluate the activity of the experimental macrocyclic lactone compound f28249-alpha against internal parasites of equids. in the critical tests, activity was determined mainly against the large parasites, but 1 critical test also included benzimidazole-resistant small strongyles. in the controlled tests, evaluation of drug activity included large parasites and stomach worms ... | 1989 | 2527481 |
| characterisation of surface antigens of strongylus vulgaris of potential immunodiagnostic importance. | when antigens prepared by detergent washes of strongylus vulgaris and parascaris equorum were probed in an enzyme-linked immunosorbent assay test with horse sera from single species infections of s. vulgaris and p. equorum, a high degree of cross-reaction between the species was demonstrated. western blot analysis of four common horse nematode species showed a large number of common antigens when probed with horse infection sera. antisera raised in rabbits against the four species, including s. ... | 1987 | 2444881 |
| two highly reiterated nucleotide sequences in the low c-value genome of panagrellus redivivus. | two families of highly reiterated satellite nucleotide (nt) sequences have been found in the genome of the sexually separated nematode panagrellus redivivus. the repeats are arranged in tandem arrays but the different satellites are not intermingled. monomeric lengths are of 155 bp for one kind and 167 bp for the other; they were named e155 and e167. the a + t content is elevated in both families (i.e., 59.5%, and 65.3%, respectively). no similarity was found between the two satellites nor to ot ... | 1990 | 2227434 |
| evidence for the release of 20-hydroxyecdysone 25-glucoside by adult female parascaris equorum (nematoda) in vitro. | 1991 | 2047376 | |
| eliminated chromatin of ascaris contains a gene that encodes a putative ribosomal protein. | chromatin diminution in the nematodes parascaris equorum and ascaris lumbricoides leads to the formation of somatic cells that contain less dna than the germ-line cells. we present molecular evidence for the coding potential of germ-line-specific dna. we report on a cdna clone that codes for a putative ribosomal protein (alep-1, for a. lumbricoides eliminated protein 1). that the corresponding gene is located in the eliminated portion of the genome indicates a difference in germ-line and somatic ... | 1991 | 2000367 |
| metabolism and fate of ecdysteroids in the nematodes ascaris suum and parascaris equorum. | when injected with [3h]ecdysone and maintained in vitro, the parasitic nematodes, ascaris suum and parascaris equorum each produced a series of polar and relatively apolar metabolites. a. suum metabolised the compound into ecdysonoic acid ([3h]eoic), ecdysone 25-glucoside ([3h]e25gluc), putative ecdysone 22-phosphate ([3h]e22p) and a series of at least six relatively apolar metabolites. all of these, except ecdysonoic acid, were hydrolysed by a crude enzyme preparation from helix pomatia, releas ... | 1991 | 1944416 |
| comparison of the efficacy of ivermectin, oxibendazole, and pyrantel pamoate against 28-day parascaris equorum larvae in the intestine of pony foals. | sixteen helminth-free pony foals were inoculated with a mean (+/- sd) 2,000 (+/- 545.5) infective parascaris equorum eggs (day 0). foals were allocated to replicates of 4, and treatments within each replicate were assigned at random. treatment administered on postinoculation day (pid) 28 included no treatment (control), 0.2 mg of ivermectin/kg of body weight, 10 mg of oxibendazole/kg, or 6.6 mg of pyrantel base (pamoate)/kg. paste formulations of the anthelmintics were administered orally. the f ... | 1991 | 1874672 |
| helminth eggs in the sludge from three sewage treatment plants in czechoslovakia. | developmental stages of 8 species of parasitic helminths were found during examination of sludge from 3 sewage treatment plants in central bohemia, czechoslovakia. the eggs were comprised from ascaris sp., toxocara sp., toxascaris leonina, parascaris equorum, enterobius vermicularis, trichuris sp., capillaria sp. and hymenolepis spp. the quantity of these organisms in 100 g of dried sludge ranged between 24-105 eggs of ascaris sp., 12-47 eggs of toxocara sp., 0-8 eggs of toxascaris leonina, 0-1 ... | 1992 | 1644362 |
| phylogeny of some ascaridoid nematodes, inferred from comparison of 18s and 28s rrna sequences. | reverse transcription of cellular rna was used to obtain sequences from regions of 18s and 26/28s ribosomal rna for eight species of ascaridoid nematodes. phylogenetic relationships among these species were inferred from the aligned sequences by maximum-parsimony and maximum-likelihood methods. seventy-nine of the 168 sites that varied were phylogenetically informative in parsimony analysis. phylogenetic inference based on maximum-likelihood analysis of all sequence sites yielded a tree of topol ... | 1992 | 1528113 |
| critical and controlled tests of activity of moxidectin (cl 301,423) against natural infections of internal parasites of equids. | the activity of moxidectin was evaluated in 1988 and 1989 against natural infections of internal parasites in 20 critical tests (n = 20 equids) and three controlled tests (n = 20 equids). two formulations, injectable administered intramuscularly (i.m.) or intraorally (i.o.) and gel i.o., were given at dose rates of 0.2, 0.3 or 0.4 mg kg-1 body weight. for the critical tests (all three dose rates evaluated), removals of second instar gasterophilus intestinalis were 93-100%, except (89%) for the i ... | 1992 | 1502789 |
| [parasitic helminths of the cecum and colon of equidae in italy]. | intestinal helminths from coecum and colon were studied in 93 equidae including 40 horses, 36 donkeys and 17 mules. a total of 38 species, 36 nematodes and 2 cestodes, were identified as follows: 1) triodontophorus serratus, 2) triodontophorus brevicauda, 3) strongylus equinus, 4) strongylus edentatus, 5) strongylus vulgaris, 6) cyathostomum tetracanthum, 7) cyathostomum coronatum, 8) cyathostomum labiatum, 9) cyathostomum labratum, 10) cyathostomum alveatum, 11) cyathostomum pateratum, 12) cyat ... | 1992 | 1339978 |
| critical tests with oxibendazole against gastrointestinal parasites of ponies. | twenty ponies were allotted to 4 groups of 5 ponies each, and oxibendazole was orally administered at dose levels of 5, 10, 15, and 20 mg/kg. in the 3 groups of ponies given the largest doses, efficacy against 3 species of strongylus was between 92 and 100% and that against small strongylids of the genera cyathostomum, cylicocyclus, cylicodontophorus, and cylicostephanus was more than 99%. all adults and 95 to 100% of larvae of the pinworm oxyuris equi were removed. in the group of ponies given ... | 1976 | 1267243 |
| critical tests and safety studies on trichlorfon as an antiparasitic agent in the horse. | three series of critical tests were completed on a combined total of 46 horses to determine the efficacy of single doses of trichlorfon against bots, ascarids, pinworms, and large strongyles. different formulations of trichlorfon were administered by tubing intragastrically, mixing with the daily grain ration, injecting intramuscularly, or pouring on the back at dose rates between 20 and 100 mg/kg. administration by feeding tended to be more efficacious for removal of bots and less toxic to the ... | 1976 | 1259212 |
| efficacy studies with three formulations of cambendazole in horses. | treatment with 3 formulations of cambendazole (paste, pellets, and suspension) was compared with thiabendazole treatment in 181 quarter horses (females and intact and altered males) of different ages in 2 experiments. the mean output of strongyle eggs, as measured by eggs per gram of feces (epg), was reduced by at least 95% by the 3 formulations of cambendazole compared with pretreatment epg and epg in simultaneously nonmedicated horses. eggs of parascaris equorum were seen in 19 of the younger ... | 1975 | 1190601 |
| studies on the development and chemotherapy of larvae of parascaris equorum (nematoda: ascaridoidea) in experimentally and naturally infected foals. | experimentally induced infections of parascaris equorum in worm-free pony foals required 14 to 17 days for migration of the larvae through the liver and lungs, and 79 to 110 days to become gametogenically functional. treatment of experimentally infected or naturally exposed foals during the parenteral phase of development, using levamisole at 8 mg/kg, a mixture of levamisole at 8 mg/kg plus piperazine at 88 mg base equivalent/kg, or dl-tetramisole at 10 mg/kg, was quite efficacious in (1) reduci ... | 1976 | 945338 |
| critical tests of anthelmintic activity of a paste formulation of thiabendazole in horses. | critical tests of the activity on large strongyles, ascarids, mature pinworms, and bots were carried out in 11 horses intraorally treated with a paste formulation of thiabendazole. the dose level of 44 mg/kg was administered to 3 horses, and the dose level of 88 mg/kg to 8 horses. removals of strongylus vulgaris and mature oxyuris equi were 100% at the 2 dose levels, and efficacy against strongylus edentatus varied from 95 to 99% and 89 to 100% for the 44- and the 88-mg/kg dose levels, respectiv ... | 1976 | 937790 |
| experimental parascaris equorum infection of foals. | six worm-free pony foals, two to four months old, were infected with parascaris equorum eggs using three different dosage regimes and killed at either 40 or 95-100 days after infection. coughing and a circulating eosinophilia were features of large infections from which only a small number of worms developed to maturity. in small infections a high percentage of the parasites matured in the small intestine and this was associated with unthriftiness. pre-patent periods of 80 and 83 days were recor ... | 1977 | 905641 |
| critical anthelmintic trials in ponies with four benzimidazoles: mebendazole, cambendazole, fenbendazole, and albendazole. | the comparative efficacy of four benzimidazoles against gastrointestinal parasites of ponies was evaluated by the critical test method. mebendazole (8.8 mg/kg), cambendazole (20 mg/kg), fenbendazole (5 mg/kg), and albendazole (2.5 and 5 mg/kg) given in single oral doses were highly effective against adult large strongylids (strongylus vulgaris, s. endentatus, s. equinus) and adult small strongylids (genera identified in order of frequency: cylicostephanus, cylicocyclus, cyathostomum, triodontoph ... | 1977 | 886410 |
| critical tests of the antiparasitic activity of thiabendazole and trichlorfon sequentially administered to horses via stomach tube. | thirteen critical tests were conducted in horses naturally infected with helminths and bots. single doses of thiabendazole (44 mg/kg of body weight) and trichlorfon (40 mg/kg of body weight) powder formulations were administered as suspensions sequentially given via stomach tube to evaluate the efficacy of the combination against the large parasites of horses. parasite removal efficacies were 100% against 2nd instar gasterophilus intestinalis and 2nd and 3rd instar gasterophilus nasalis and 82 t ... | 1977 | 879569 |
| an evaluation of ethyl-6-ethoxybenzothiazole-2-carbamate (sch 18099) for anthelmintic activity in domestic animals. | ethyl-6-ethoxybenzothiazole-2-carbamate (sch 18099) was evaluated for efficacy against natural helminth infections in ponies, pigs, lambs and chickens. sixteen critical trials were conducted in ponies at dosages of 15 to 150 mg/kg. at 15 mg/kg, efficacy against adult and larval oxyuris equi was 100% and 91% and against small strongyles it was 98%. efficacy levels were 95% against strongylus vulgaris and s. edentatus at the 20 mg/kg dosage. in two trials at 100 mg/kg efficacy against parascaris e ... | 1977 | 864223 |
| [control of the equine ascarid, parascaris equorum (goeze, 1782), with panacur]. | 1977 | 843335 | |
| the distribution of concanavalin a binding sites on the intestinal epithelium of the nematodes ascaris suum and parascaris equorum. | receptors for concanavalin a (con a), were localized on the intestinal epithelium of the nematodes ascaris suum and parascaris equorum. fixed tissue incubated in 3h-con a showed labeling of the microvilli surface and basal membrane. using con a coupled with peroxidase, the tips of the microvilli of ascaris suum and the tips and lateral surfaces of parascaris equorum were stained. the basal membrane of both species was also labeld. no labeling was observed on control tissue incubated without con ... | 1976 | 791496 |
| critical tests of the anthelmintic febantel in the horse: activity of a paste formulation alone or with a trichlorfon paste. | critical tests were carried out in 10 horses to evaluate the antiparasitic activity of febantel given alone or with trichlorfon. paste formulations were administered intraorally at dose levels of 6 mg of febantel (active ingredient)/kg and 35 mg of trichlorfon (active ingredient)/kg. in 5 tests with febantel alone, removal of 100% was recorded for mature or immature parascaris equorum from 2 infected horses. strongylus vulgaris from 4 infected horses, s edentatus from 5 infected horses, and matu ... | 1978 | 697152 |
| pathologic changes and pathogenesis of parascaris equorum infection in parasite-free pony foals. | parasite-free pony foals (n = 10) were infected orally with 1000,000 parascaris equorum embryonated eggs. one pony foal each was euthanatized on days 1, 3, 5, 7, 11, 16, 23, 27, 42, or 80 after infection. foals infected for more than 7 days showed signs of coughing, anorexia, rough coat, and weight loss. cellular changes in the blood were mild anemia, marked eosinophilia, and leukopenia. gross postmortem lesions included hemorrhage, edema, and white-to-yellow necrotic foci (0.5 to 1.00 mm) in lu ... | 1978 | 677534 |
| a pathological study of the lungs of foals infected experimentally with parascaris equorum. | 1978 | 659680 | |
| homocytotropic response to guinea-pigs to antigen extracts from formalized and unformalized parascaris equorum. | a homocytotropic anaphylactic response is described in guinea-pigs sensitized with antigen from parascaris equorum. this antigen was not sensitive to prolonged storage in formalin. some adult ascarid extracts prepared from worms that had been stored for 14 days in 10 per cent formalin before use, retained their ability to produce an allergenic response. the antisera withstood heat inactivation at 56 degrees for up to 7 h or treatment with 2-mercaptoethanol and were still capable of eliciting a s ... | 1978 | 631874 |
| the development of immunity to parascaris equorum infection in the foal. | following infection with 8000 parascaris equorum eggs in two- to four-week-old foals reared under worm-free conditions a high percentage of the infective dose completed its tissue migration and returned to the small intestine. patent infections were establisehd between 81 and 104 days after infection and high faecal egg counts were recorded. a group of six- to 12-month-old foals, which had been either reared under worm-free conditions or exposed to natural ascarid and strongyle infections on pas ... | 1979 | 574660 |
| hepatic pathology of experimental parascaris equorum infection in worm-free foals. | 1979 | 570571 | |
| [studying the faeces for the presence of parasites in horses and ponies (author's transl)]. | in 3,791 horses and ponies submitted to the department of internal disease of farm animals of the faculty of veterinary medicine, utrecht, the faeces were studied for the presence of parasites. the results were classified by age groups and months of arrival. eggs of the strongylus type were found to be present in 57.3 per cent of the faecal samples, eggs of parascaris equorum were present in 6.1 per cent, eggs of oxyuris equi in 1.2 per cent, eggs or larvae of dictyocaulus arnfieldi in 0.2 per c ... | 1978 | 567859 |
| homocytotropic response of guinea-pigs to antigen extracts from formalized and unformalized parascaris equorum. | a homocytotropic anaphylactic response is described in guinea-pigs sensitized with antigen from parascaris equorum. this antigen was not sensitive to prolonged storage in formalin. some adult ascarid extracts prepared from worms that had been stored for 14 years in 10 per cent formalin before use, retained their ability to produce an allergenic response. the antisera withstood heat inactivation at 56 degrees for up to 7 h or treatment with 2-mercaptoethanol and were still capable of eliciting a ... | 1977 | 564869 |
| anthelmintic efficiency of fenbendazole in equines. | a single oral dose of fenbendazole (fbz) at 10 mg/kg body mass was given to 5 donkeys. a further 5 donkeys were dosed with a medicated lick (1 mg fbz/g lick) until the oral consumption was 10 mg/kg body mass. in both trials fbz was highly effective against adults of the following genera: cyathostomum, cylicocyclus, cylicostephanus, cylicodontophorus, poteriostomum, cabellonema, craterostomum and triodontophorus; similarly high efficiency was obtained against the following species: habronema maju ... | 1979 | 553963 |
| satellite dna properties of the germ line limited dna and the organization of the somatic genomes in the nematodes ascaris suum and parascaris equorum. | during the early cleavage divisions in some ascarids, parts of the chromosomes are eliminated from the somatic blastomeres ("chromatin diminution", boveri, 1887) while the chromosomes in the germ line cells maintain their integrity. to characterize the germ line and soma genome, dna was isolated from gametes and embryonic somatic cells of two ascarid species, parascaris equorum var. univalens and ascaris suum. it was shown that the germ line limited dnas of these species have the same density an ... | 1979 | 510087 |
| the migration and development of parascaris equorum in the horse. | 1979 | 489235 | |
| critical tests and clinical trials on oxibendazole in horses with special reference to removal of parascaris equorum. | the efficacy of oxibendazole given at dose level of 10 mg/kg of body weight was determined by 10 critical tests in foals and by 2 clinical trials in 20 foals (16 treated, 4 nontreated), with special interest in the drug activity against parascaris equorum. the drug was uniformly efficacious (100%) against p equorum in the 10 critical-test foals, each having between 22 and 236 ascarids. posttreatment reductions of ascarid egg counts in fecal samples were also 100% in suckling foals treated with o ... | 1979 | 475125 |
| critical test evaluation of butamisole against gastrointestinal parasites of horses and ponies. | a critical test was performed to evaluate the anthelmintic properties of an injectable butamisole formulation and to compare the efficiency with that of a commercially available piperazine-thiabendazole anthelmintic. the test was done in 10 horses and 15 ponies with naturally acquired parasitic infections. butamisole was administered at the dose level of 2.5 or 3.75 mg/kg of body weight by either subcutaneous or deep intramuscular injection. given at the dose level of 2.5 mg/kg, butamisole was h ... | 1979 | 453676 |
| [autoradiographic localization of rna synthesis in vitro during oogenesis in parascaris equorum]. | technical elaboration of in vitro incubation of parascaris equorum gonads with 3h-uridine has permitted, for the first time, the study of rna synthesis during oogenesis along the whole gonadic tube. in germ cells, oocytes in diakinesis (oviduct) and in division of maturation (uterus) show no label. on the contrary oogonia and growing oocytes in ovary are labelled. rna synthesis is always detected in all parietal cells but is more active in oviduct and uterus where the gonadic wall is particularl ... | 1977 | 405148 |
| an evaluation of the efficacy of oxfendazole against the common nematode parasites of the horse. | in a controlled trial in naturally-infected young ponies, oxfendazole administered orally at dose-rates of 10 mg per kg and 50 mg per kg resulted in complete elimination of trichostrongylus axei, parascaris equorum, oxyuris equi and adult strongylus vulgaris. also, all migrating strongylus edentatus larvae recovered from the subperitoneal tissues of the flank were found to be dead. minimum efficiencies of 99.8 per cent and 99.1 per cent were obtained against adult small strongyles (trichonema sp ... | 1978 | 364817 |
| toxocara infection in pigs. the use of indirect fluorescent antibody tests and an in vitro larval precipitate test for detecting specific antibodies. | an in vitro larval precipitate test using second-stage toxocara canis larvae and an indirect fluorescent antibody (ifa) test employing cuticles of t. canis larvae as antigen were evaluated using antisera produced in pigs experimentally infected with t. canis, t. cati, ascaris suum, toxascaris leonina and parascaris equorum. the former test was both specific and sensitive and is suggested as a reliable and simple method of detecting toxocara antibodies in pigs. the latter test was considered unsu ... | 1977 | 328560 |
| critical tests of suspension, paste, and pellet formulations of cambendazole in the horse. | three formulations of cambendazole were evaluated for anthelmintic activity by critical testing method in 21 horses. cambendazole suspension was administered via stomach tube at the dose rate of 10 mg/kg to 3 horses and at the dose rate of 20 mg/kg to 3 horses. cambendazole paste was given intraorally to 8 horses, and the pellet formulation was fed to 7 horses at the dose rate of 20 mg/kg. anthelmintic activity of cambendazole was similar for all dose rates and formulations. gasterophilus intest ... | 1975 | 123710 |