Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
|---|
| induction of apoptosis in hl-60 cells treated with medicinal herbs. | in order to develop a new apoptosis inducer, we screened 22 crude drugs for their apoptosis-inducing activity. it was found that glycyrrhiza uralensis, cynomorium songaricum, eucommia ulmoides, phellodendron amurense, cinnamomum cassia and paeonia lactiflora induced the death of hl-60 cells. to investigate the mechanism of apoptosis induced by these six crude drugs, the mitochondrial transmembrane potential and the activity of caspase-3 were measured. reduced mitochondrial transmembrane potentia ... | 2003 | 14587878 |
| tochu (eucommia ulmoides) leaf extract prevents ammonia and vitamin c deficiency induced gastric mucosal injury. | the ingestion of dietary antioxidants, including vitamin c (vc), is suggested to play an important role in the prevention of gastric cancer associated with helicobacter pylori (hp) infection. recently, water extracts of tochu (du-zhong, eucommia ulmoidea oliver) leaves (wetl) have been reported to have potent antioxidant and antimutagenic effects. the present study investigated the effect(s) of vc and wetl on gastric mucosal injury induced by ammonia and a vc deficient diet. guinea pigs fed the ... | 2003 | 14561529 |
| study on the inhibitory effects of korean medicinal plants and their main compounds on the 1,1-diphenyl-2-picrylhydrazyl radical. | a 1,1-diphenyl-2-picrylhydrazyl (dpph) radical-generating system was used to evaluate the antioxidant properties of korean medicinal plants that have been used widely as folk medicines for several disorders, as well as compounds isolated from them. among the rosaceae, rosa rugosa and rosa davurica showed strong dpph radical-scavenging activity. the most effective medicinal plant from families other than rosaceae was cedrela sinensis, followed in order by nelumbo nucifera, eucommia ulmoides, zant ... | 2003 | 13678241 |
| pharmacological action of eucommia ulmoides, oliv. | 1957 | 13480752 | |
| [guttapercha content of the leaves of eucommia ulmoides oliv]. | 2006 | 13305607 | |
| [advances in the study of chemical constituents and pharmacology of eucommia ulmoides oliver]. | 2003 | 12964557 | |
| [effects of growth regulator, full exposure and mist spray on the cutting of eucommia ulmoides]. | to study the effects of growth regulator on the cutting method of eucommia ulmoides seedlings. | 2001 | 12901096 |
| relationship between endogenous indole-3-acetic acid and abscisic acid changes and bark recovery in eucommia ulmoides oliv. after girdling. | eucommia ulmoides (eucommiaceae), a traditional chinese medicinal plant, is often subjected to severe manual peeling of its bark. if the girdled trunk is well protected from desiccation, new bark forms within 1 month. it has been proposed that phytohormones play a key role in this process. research has been conducted to determine the distribution of endogenous indole-3-acetic acid (iaa) and abscisic acid (aba) during the bark recovery, using high-performance liquid-chromatography (hplc) and fluo ... | 2003 | 12869522 |
| [studies on the phenylpropanoids from eucommia ulmoides]. | to study the chemical constituents from the leaves of eucommia ulmoides. | 2002 | 12774353 |
| biotransformation of pinoresinol diglucoside to mammalian lignans by human intestinal microflora, and isolation of enterococcus faecalis strain pdg-1 responsible for the transformation of (+)-pinoresinol to (+)-lariciresinol. | by anaerobic incubation of pinoresinol diglucoside (1) from the bark of eucommia ulmoides with a fecal suspension of humans, eleven metabolites were formed, and their structures were identified as (+)-pinoresinol (2), (+)-lariciresinol (3), 3'-demethyl-(+)-lariciresinol (4), (-)-secoisolariciresinol (5), (-)-3-(3", 4"-dihydroxybenzyl)-2-(4'-hydroxy-3'-methoxybenzyl)butane-1, 4-diol (6), 2-(3', 4'-dihydroxybenzyl)-3-(3", 4"-dihydroxybenzyl)butane-1, 4-diol (7), 3-(3"-hydroxybenzyl)-2-(4'-hydroxy- ... | 2003 | 12736449 |
| primary structural determination of n-terminally blocked peptides from the bark of eucommia ulmoides oliv by mass spectrometric analysis. | sequencing of n-terminally blocked proteins/peptides is a challenge since these molecules inhibit processing by edman degradation. by using high accuracy fourier transform ion cyclotron resonance (fticr) tandem mass spectrometry and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (maldi-tofms), the primary structures of two novel n-terminally blocked antifungal peptides (eafp1 and eafp2), purified from the bark of eucommia ulmoides oliv, have been determined. the res ... | 2003 | 12717762 |
| rapid and simultaneous analysis of some bioactive components in eucommia ulmoides by capillary electrophoresis. | a micellar electrokinetic chromatography method was established for the qualitative and quantitative determination of three groups of bioactive components, iridoids, flavonoids and phenolic compounds, in eucommia ulmoides. of the eleven bioactive components being studied, ten were successfully separated in 50 mm boric acid buffer at ph 9.5, with 50 mm sodium dodecylsulfate and 4% 1-butanol, at a voltage of 20 kv, temperature of 20 degrees c and injection under high pressure at 138 kpa for 5 s in ... | 2003 | 12650263 |
| inhibitory effect of eucommia ulmoides oliv. on oxidative dna damage in lymphocytes induced by h2o2. | this study used the alkaline single cell gel electrophoresis assay (comet assay) to investigate the effect of water extracts of roasted cortex and leaves from du-zhong on dna damage in lymphocytes induced by h(2)o(2). the results showed that the dna damage in human lymphocytes increased with an increase in the concentration of h(2)o(2) (0-200 micro;m), but that the water extracts from du-zhong (0-2 g l(-1)) only slightly affected dna damage. the inhibitory effect of leaf extract on dna damage in ... | 2003 | 12616594 |
| time-course of programmed cell death during leaf senescence in eucommia ulmoides. | leaves of eucommia ulmoidesoliv. harvested between april to november were examined for programmed cell death (pcd) during growth and senescence. leaves developed in april, becoming fully expanded in late may, remaining unchanged until november when they started to dehisce. falling leaves retained a green color. our results showed that (1) mesophyll cells gradually reduced their nuclei from september to november, (2) positive tunel signals appeared on the nuclei from august, (3) ladder-like dna f ... | 2003 | 12605294 |
| [studies on flavonoids from leave of eucommia ulmoides oliv]. | to separate the constituents from eucommia ulmoides. | 2000 | 12512449 |
| in-situ chemical analyses of trans-polyisoprene by histochemical staining and fourier transform infrared microspectroscopy in a rubber-producing plant, eucommia ulmoides oliver. | the localization of polyisoprene in young stem tissues of eucommia ulmoides oliver was investigated by histochemical staining and fourier transform infrared (ft-ir) microspectroscopy. the fibrous structures were stained with oil red o. ft-ir microspectroscopic analysis proved that the fibrous structures were trans-polyisoprene. granular structures stained with the dye, and characteristic absorptions at 2,960 cm(-1) and 1,430 cm(-1) in ft-ir suggested that trans-polyisoprene accumulated in the vi ... | 2002 | 12355153 |
| crystallization and preliminary crystallographic studies of a novel antifungal protein with five disulfide bridges from eucommia ulmoides oliver. | two antifungal proteins, named eucommia antifungal peptides 1 and 2 (eafp1 and eafp2), have been purified from the bark of the tree e. ulmoides oliver and show a relatively broad spectrum of antifungal activity against several agriculturally important plant pathogens. one of these small proteins (eafp2) has been crystallized. the crystal belongs to space group p2(1), with unit-cell parameters a = 19.01, b = 23.16, c = 30.69 a, beta = 98.54 degrees. 1.0 a resolution data were collected from an ea ... | 2002 | 12351831 |
| [sequence analysis of 25s rdna from chinese medicinal plant duzhong eucommia ulmoides oliv]. | to provide new molecular data for the identification of the chinese medicinal plant duzhong (eucommia ulmoides). | 1998 | 12242816 |
| a new monoterpene from the bark of eucommia ulmoides. | a new monoterpene, eucommidiol (1), was isolated from the bark of eucommia ulmoides oliv. (eucommiaceae), together with a known compound 1,4a,5,7a-tetrahydro-7-hydroxymethyl-cyclopenta[c]pyran-4-carboxylic methyl ester. the structure of 1 was characterized as 6,6a-di(hydroxymethyl)-3,3a,4,6a-tetrahydro-2h-cyclopenta[b]furan-2-one on the basis of chemical and spectral evidence including 2dnmr studies. | 2002 | 12118509 |
| two novel antifungal peptides distinct with a five-disulfide motif from the bark of eucommia ulmoides oliv. | two antifungal peptides, named eafp1 and eafp2, have been purified from the bark of eucommia ulmoides oliv. each of the sequences consists of 41 residues with a n-terminal blockage by pyroglutamic acid determined by automated edman degradation in combination with the tandem mass spectroscopy and the c-terminal ladder sequencing analysis. the primary structurs all contain 10 cysteines, which are cross-linked to form five disulfide bridges with a pairing pattern (c1-c5, c2-c9, c3-c6, c4-c7, c8-c10 ... | 2002 | 12067732 |
| constituents and pharmacological effects of eucommia and siberian ginseng. | the bark and leaves of eucommia ulmoides oliv (eucommiaceae) and "siberian ginseng" (ezoukogi in japanese) prepared from the root bark or stem bark of eleutherococcus senticosus maxim (acanthopanax senticosus harms) have been used as tonic and anti-stress drug. the extracts of eucommia showed anti-hypertensive, anti-complementary, anti-oxidative, and anti-gastric ulcer effects, and promoting collagen synthesis, accelating granuloma formation, and other pharmacological effects. the siberian ginse ... | 2001 | 11749801 |
| the occurrence of geometric polyprenol isomers in the rubber-producing plant, eucommia ulmoides oliver. | the chain length and geometric isomerism of polyprenols from eucommia ulmoides oliver were analyzed using supercritical fluid chromatography. after intensive effort to establish separation conditions for geometric isomers, a phenyl-bonded silica gel-packed column was found that cleanly separated poly-trans and -cis prenols. the presence of long-chain poly-trans prenols (>9 mers) was confirmed for the first time in plants. trans isomers were found in the leaf, seed coat, and root, but not in the ... | 2001 | 11521971 |
| [a reversed-phase high performance liquid chromatographic method for the determination of pinoresinol diglucopyranoside in eucommia ulmoides oliv]. | a reversed-phase high performance liquid chromatographic method for the determination of (+)-pinoresinol-di-o-beta-d-glucopyranoside in the bark of eucommia ulmoides was established. the air-dried bark of e. ulmoides was ground into powder and extracted continuously with methanol. the extract was evaporated under reduced pressure, then suspended in water. this suspension being subjected to column chromatography was eluted successively with water, 30%, 50% and 90% aqueous solution of ethanol. the ... | 1998 | 11326985 |
| antioxidant actions of du-zhong (eucommia ulmoides oliv.) toward oxidative damage in biomolecules. | this study aimed to investigate the antioxidant effect of water extracts of du-zhong (wedz) on oxidative damage in biomolecules such as deoxyribose, dna, and 2'-deoxyguanosine (2'-dg) as induced by fenton reaction. the wedz used included leaves, raw cortex, and roasted cortex. all of the wedz inhibited the oxidation of deoxyribose induced by fe(3+)-edta/h2o2/ascorbic acid in a concentration dependent manner. at a concentration of 1.14 mg/ml, the inhibitory effect of the extracts of leaves, roast ... | 2000 | 11210714 |
| reactive oxygen species scavenging activity of du-zhong (eucommia ulmoides oliv.) and its active compounds. | the biologically active compounds and free radical-/ or reactive oxygen species (ros)-/ scavenging effect of water extract from du-zhong (wedz) were investigated. the wedz used included leaves, raw cortex, and roasted cortex. the hot water extract of du-zhong leaves showed marked activity as a ros scavenger, and the scavenging effect was concentration dependent. the extract of roasted cortex exhibited a modest scavenging effect on ros, while the extract of raw cortex had the weakest scavenging e ... | 2000 | 10956129 |
| granuloma maturation in the rat is advanced by the oral administration of eucommia ulmoides oliver leaf. | we have reported that collagen metabolism was improved by the administration of eucommia ulmoides oliver leaf. in this paper, we examine the granuloma maturation and deposition of collagen in the granuloma of rats due to the oral administration of this leaf. after 3 weeks of the oral administration, granuloma formation was induced by the formalin soaked filter paper-pellet method. a week later, the developing granuloma was dissected. granuloma formation was significantly increased due to ingesti ... | 2000 | 10706412 |
| the promoting effect of eucommiol from eucommiae cortex on collagen synthesis. | the effect of a methanol extract of eucommiae cortex on collagen synthesis was investigated in false aged model rats. granuloma formation and collagen synthesis were significantly increased by the administration of the methanol extract of eucommiae cortex. the effective component of eucommiae cortex was then discussed by fractionating the methanol extract of eucommiae cortex. eucommiol, a main component in the water fraction of the methanol extract, was found to be an effective compound. in our ... | 2000 | 10706411 |
| changes in lactate dehydrogenase and 3-hydroxyacetyl-coa dehydrogenase activities in rat skeletal muscle by the administration of eucommia ulmoides oliver leaf with spontaneous running-training. | we examined the effect of eucommia ulmoides oliver leaf on rat skeletal muscles together with spontaneous running-training in terms of the isozyme profile and specific activity of lactate dehydrogenase (ldh; ec 1.1.1.27) and 3-hydroxyacetyl-coa dehydrogenase (had; ec 1.1.1.35). on the twenty-ninth day of the experimental period, a mandatory endurance running exercise (treadmill, 7 degrees grade) was conducted. twenty-four hours later, the rats were sacrificed and the skeletal muscles and other o ... | 1999 | 10513617 |
| improvement in the turnover rate of the stratum corneum in false aged model rats by the administration of geniposidic acid in eucommia ulmoides oliver leaf. | we earlier reported that collagen synthesis in false aged model rats was stimulated by the administration of a methanol extract from the leaves of eucommia ulmoides oliver. when the methanol extract was fractionated to n-hexane, ethyl acetate, acetone and methanol fractions by silica gel chromatography, we discovered that geniposidic acid and aucubin, contained in the acetone fraction, were the active ingredients. in the current study, we set out to examine if active compounds found in the eucom ... | 1999 | 10408230 |
| the promoting effects of geniposidic acid and aucubin in eucommia ulmoides oliver leaves on collagen synthesis. | we have reported that collagen synthesis was stimulated by the administration of a hot water extract from the leaves of eucommia ulmoides oliver, eucommiaceae (du-zhong leaves) in false aged model rats. in this paper, we set out to examine the compounds in du-zhong leaves that stimulated collagen synthesis in false aged model rats. in experiment 1, a methanol extract of du-zhong leaves also stimulated collagen synthesis in aged model rats. an acetone fraction was derived from the methanol extrac ... | 1998 | 9881644 |
| anti-human immunodeficiency virus activity of oligosaccharides from rooibos tea (aspalathus linearis) extracts in vitro. | the active substances, acid polysaccharides, were extracted with 1% sodium hydroxide from the leaves of rooibos tea (aspalathus linearis), du zhong cha (eucommia ulmoides oliv.) and japanese tea leaves (camellia sinensis var. sinensis). the alkaline extracts of rooibos tea and du-zhong tea leaves, but not japanese tea leaves suppressed the hiv-induced cytopathicity using hiv (htlv-iii) infected mt-4 cells, having extremely low cytotoxicity: its 50% effective concentration (ec50) was 12-67 microg ... | 1997 | 9209319 |
| the preventive effect of ginseng with du-zhong leaf on protein metabolism in aging. | stimulation of collagen synthesis prevents the aging process. we found such a synergistic effect by using the leaves of eucommia ulmoides oliver, eucomiaceae (du-zhong leaf) and the roots of panax ginseng c. a. meyer (ginseng). the formula consists of amounts which exert no effect when used individually. we tested several formula ratios of ginseng and du-zhong leaf, 1:1, 1:2, 1:3 and 1:4, and concluded that the last two formulas were effective. however, we did not observe a significant differenc ... | 1997 | 9084879 |
| isolation and identification of alpha-glucosidase inhibitors from tochu-cha (eucommia ulmoides). | alpha-glucosidase inhibitory activity was found in aqueous methanol extracts of tochu-cha, dried leaves of eucommia ulmoides (eucommiaceae). five active principles against yeast enzyme were isolated and characterized. among them, quercetin (1, ki: 8.5 x 10(-6) m) was considered to contribute mostly to the activity of the tochu leaves. in regard to an animal alpha-glucosidase, rat intestinal sucrase activity was also inhibited by 1. | 1997 | 9028049 |
| antimutagenicity of tochu tea (an aqueous extract of eucommia ulmoides leaves): 1. the clastogen-suppressing effects of tochu tea in cho cells and mice. | the suppressing effect of crude extracts of tochu tea, an aqueous extract of eucommia ulmoides leaves and a popular beverage in japan, on the induction of chromosome aberrations in cho cells and mice was studied. when cho cells were treated with tochu tea crude extract after mmc treatment, the frequency of chromosome aberrations was reduced. out of 17 tochu tea components, 5 irridoids (geniposidic acid, geniposide, asperulosidic acid, deacetyl asperulosidic acid, and asperuloside) and 3 phenols ... | 1997 | 9025787 |
| antimutagenicity of tochu tea (an aqueous extract of eucommia ulmoides leaves): 2. suppressing effect of tochu tea on the urine mutagenicity after ingestion of raw fish and cooked beef. | the effect of tochu tea, which is an aqueous extract of eucommia ulmoides leaves and a popular-beverage in japan, on the urine mutagenicity before and after ingestion of raw fish and cooked beef was studied using salmonella typhimurium yg1024. urines were collected from seven healthy, non-smoking japanese women before and after ingestion of raw fish and cooked beef. in experiment 1,3 were in a control group and 4 were in a tochu tea-drinking group (2000 ml per day). the mutagenicity of urine fro ... | 1996 | 9008721 |
| research note: effect of tu-chung leaf (eucommia ulmoides) on egg production performance, egg quality, and fat metabolism in laying hens at a late production stage. | the effects of tu-chung leaf (eucommia ulmoides) supplementation on egg production performance, egg quality, and fat metabolism were investigated in laying hens at a late production stage. white leghorn laying hens at 20 mo of age were provided ad libitum access to a practical diet with or without tu-chung leaf supplement for 3 mo. during the experimental period, egg production rate, egg weight, and feed intake were recorded every day. egg samples from the last 3 days were collected to measure h ... | 1993 | 8265504 |
| [treatment of patients with hypertension with an extract of the leaves of eucommia ulmoides]. | 1983 | 6868493 | |
| regeneration of re-covered bark in eucommia ulmoides. | the girdled trunk of eucommia ulmoides, sometimes could not regenerate a new bark due to ringed surface necrosis. but, if an extension of 10cm of the bark on each end of the necrotic part was removed in time and re-covered with new bark taken from another tree, the re-covered bark and the newly girdled part could heal together one week after. opposite to the necrotic surface the loose part of the re-covered bark regenerated callus from the phloem ray cells. if the re-covered part was very close ... | 1983 | 6867680 |
| anticomplementary activity of the constituents of eucommia ulmoides bark. | a study was made on the anticomplementary activity of the lignoid and iridoid derivatives isolated from the bark of eucommia ulmoides as well as the enzymatic hydrolysis products of the isolated iridoid glucosides. | 2014 | 3193787 |
| [chemical analysis of duzhong (eucommia ulmoides) bark and leaves]. | 1986 | 2948723 | |
| [a study of commonly used substitutes for chinese drug cortex eucommiae(duzhong)]. | we have found that 48 species belonging to 10 families and 17 genera are being used as ethnic substitutes for cortex eucommiae (duzhong). a key to all the species has been made to identify them and to distinguish them from eucommia ulmoides. | 1989 | 2635596 |
| [experimental studies on the significance of processing eucommia ulmoides oliv]. | the inhibitory action on isolated uterus of middle-pregnancy mice have been compared in eucommia ulmoides and its salt water processed product. it has been found that after processing the inhibitory action on the automatic contraction of isolated uterus, the antagonism on spasmodis contraction caused by acetylcholine are increased, but the antagonism on spasmodis contraction caused by pituitarium posterius and the pb content are decreased. | 1989 | 2619889 |
| [measurement of mefv in 66 cases of asthma in the convalescent stage and after treatment with chinese herbs]. | this paper reported the measurement of maximal expiratory flow-volume curve (mefv) for 66 cases of asthmatics in the convalescent stage. among which the data of fev, pef, v75, v50, v25 in 35 cases (53.03% of the total) gave different abnormal as compared with healthy persons. it showed that in the convalescent stage, most of the asthmatics still possessed obstruction of airways and chiefly of small airways. 35 cases of asthmatics in the convalescent stage was given the chinese herbal decoction o ... | 1989 | 2611953 |
| [comparison of some trace element contents of eucommia ulmoides oliv. and its processed products]. | a comparison of the contents of 7 trace elements (zn, mn, cu, fe, ca, p, pb) in eucommia ulmoides and its processed products has been made, and the significance of processing eucommia ulmoides is discussed in light of the experimental results. | 1989 | 2597322 |
| a study on the mutagenicity of 102 raw pharmaceuticals used in chinese traditional medicine. | the mutagenic potential of traditional chinese drugs was studied. after extraction with boiling water and frozen vacuum drying, preparations from 102 raw drugs were tested with the ames test, and the micronucleus and chromosomal aberration assays in mice in vivo. astragalus mongholicus bunge (+s9), sophora japonica l. (+/- s9) and eucommia ulmoides oliv. (+/- s9) were found to significantly induce his+ revertants in salmonella typhimurium ta98 and/or ta100. besides these 3, 10 other extracts wer ... | 1991 | 2027343 |
| [identification of morphology and inorganic elements of eucommia ulmoides oliv. produced in sichuan by applying scanning electron microscope with energy dispersive x-ray analysis]. | a research on the identification of morphology and inorganic elements of eucommia ulmoides produced in sichuan has been made by applying scanning electron microscope; energy dispersive x-ray analysis. qualitative and semi-quantitative analyses of the inorganic elements in the observed areas have been obtained. | 1992 | 1418547 |
| letter: isolation and synthesis of pinoresinol diglucoside, a major antihypertensive principle of tu-chung(eucommia ulmoides, oliver). | 1976 | 956566 | |
| a contribution to our knowledge of tu-chung--eucommia ulmoides. | 1979 | 420159 |