Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
|---|
| acceptability of a/h1n1 vaccination during pandemic phase of influenza a/h1n1 in hong kong: population based cross sectional survey. | objective: to investigate the intention of the hong kong general population to take up vaccination against influenza a/h1n1. setting cross sectional population based anonymous survey. participants random sample of 301 adults interviewed by telephone (response rate 80%). main outcome measure: intention to take up vaccination against influenza a/h1n1 under five hypothetical scenarios: vaccination is free; vaccination per dosage costs less than $hk100 ( pound8; euro9; $13), $hk101-200, or more than ... | 2009 | 19861377 |
| influenza-related hospitalisations in children. | to describe the disease burden, clinical pattern and outcome of influenza-related hospitalisations in children. | 2009 | 19845841 |
| pressure ulcer development in older residents in nursing homes: influencing factors. | this paper is a report of a study assessing pressure ulcer incidence and factors affecting pressure ulcer development among older nursing home residents. | 2009 | 19824910 |
| summaries for patients. the effects of hand washing and facemasks on prevention of influenza infection. | 2009 | 19805764 | |
| structures of receptor complexes formed by hemagglutinins from the asian influenza pandemic of 1957. | the viruses that caused the three influenza pandemics of the twentieth century in 1918, 1957, and 1968 had distinct hemagglutinin receptor binding glycoproteins that had evolved the capacity to recognize human cell receptors. we have determined the structure of the h2 hemagglutinin from the second pandemic, the "asian influenza" of 1957. we compare it with the 1918 "spanish influenza" hemagglutinin, h1, and the 1968 "hong kong influenza" hemagglutinin, h3, and show that despite its close overall ... | 2009 | 19805083 |
| the first novel influenza a (h1n1) fatality despite antiviral treatment and extracorporeal membrane oxygenation in hong kong. | we report the first fatality caused by novel influenza a (h1n1) infection despite having the diagnosis confirmed and being given antiviral treatment after hospitalisation. this patient was also the first with influenza a (h1n1) to be supported with extracorporeal membrane oxygenation in hong kong. although extracorporeal membrane oxygenation is an effective means of supporting patients with refractory hypoxaemia on high mechanical ventilatory support, it is labour-intensive and technically deman ... | 2009 | 19801697 |
| epidemiology and clinical presentations of human coronavirus nl63 infections in hong kong children. | human coronavirus nl63 (hcov-nl63) has been found in children presenting with respiratory tract infections (rtis). however, the epidemiology and clinical course of this newly identified virus have not been fully elucidated. this study investigated the epidemiology, seasonality, and clinical features of hcov-nl63 in hong kong children. this study consisted of two cohorts of children hospitalized in a university-affiliated teaching hospital. in the 12-month retrospective part of the study, reverse ... | 2009 | 19759228 |
| multiplex molecular detection of respiratory pathogens in children with asthma exacerbation. | up to 80% of asthma exacerbations in white children are associated with viral upper respiratory infections. the relative importance of different respiratory pathogens and relevant microbiological data in asian children are unclear. this study elucidated the epidemiology of respiratory infections in hong kong children with asthma exacerbation. | 2010 | 19749009 |
| the emergence of the novel h1n1 virus: implications for global mental health. | 2009 | 19747424 | |
| detection of an oseltamivir-resistant pandemic influenza a/h1n1 virus in hong kong. | 2009 | 19736041 | |
| associations of polymorphisms in the apolipoprotein a1/c3/a4/a5 gene cluster with familial combined hyperlipidaemia in hong kong chinese. | familial combined hyperlipidaemia (fch) is the most common genetic dyslipidaemia associated with coronary artery disease. single nucleotide polymorphisms (snps) and haplotypes in the apoa1/c3/a4/a5 gene cluster are associated with fch in caucasians and with elevated triglycerides (tg) in various ethnic groups. we examined these associations with fch in hong kong chinese. | 2010 | 19732897 |
| the burden of influenza in children: time for prevention. | 2009 | 19722913 | |
| virologically confirmed population-based burden of hospitalization caused by influenza a and b among children in hong kong. | we sought to determine the virologically confirmed hospitalization rates associated with influenza virus infection among hong kong children. | 2009 | 19722912 |
| clinical and molecular epidemiology of human rhinovirus c in children and adults in hong kong reveals a possible distinct human rhinovirus c subgroup. | a novel human rhinovirus (hrv) species, hrv-c, was recently discovered, but its clinical features and epidemiology, compared with hrv-a and hrv-b, remains poorly understood, especially in adults. | 2009 | 19708791 |
| willingness of hong kong healthcare workers to accept pre-pandemic influenza vaccination at different who alert levels: two questionnaire surveys. | to assess the acceptability of pre-pandemic influenza vaccination among healthcare workers in public hospitals in hong kong and the effect of escalation in the world health organization's alert level for an influenza pandemic. | 2009 | 19706937 |
| seasonal effects of influenza on mortality in a subtropical city. | influenza has been associated with a heavy burden of mortality. in tropical or subtropical regions where influenza viruses circulate in the community most of the year, it is possible that there are seasonal variations in the effects of influenza on mortality, because of periodic changes in environment and host factors as well as the frequent emergence of new antigenically drifted virus strains. in this paper we explored this seasonal effect of influenza. | 2009 | 19698116 |
| seasonal influenza activity in hong kong and its association with meteorological variations. | influenza seasons appear consistently in the temperate regions, but are more variable in tropical/subtropical regions. the determinant for such variation remains poorly understood. this study documented the activity of influenza over a 10-year period in hong kong; examining its association with changes in temperature and relative humidity. the two types of influenza exhibited different correlations with meteorological variations. influenza a showed two seasonal peaks occurring respectively in wi ... | 2009 | 19697414 |
| factors affecting quickvue influenza a + b rapid test performance in the community setting. | rapid diagnosis of influenza can facilitate timely clinical management. we evaluated the performance of the quickvue influenza a + b test (quidel, san diego, ca) in a community setting and investigated the factors affecting test sensitivity. we recruited 1008 subjects from 30 outpatient clinics in hong kong between february and september 2007. each subject provided 2 pooled pairs of nose and throat swabs; 1 pair was tested by the quickvue rapid test on site, and the other pair was sent to a labo ... | 2009 | 19679233 |
| contributors to surgical in-patient satisfaction--development and reliability of a targeted instrument. | patient satisfaction is an important indicator of healthcare system performance. high patient satisfaction is associated with greater trust in caregivers, improved compliance with treatment recommendations and a better quality of life (qol). there are few validated instruments to measure surgical patients satisfaction. the aim of this study was to develop a culturally-specific patient satisfaction instrument, for use as an outcome measure in evaluating surgical services. | 2009 | 19656753 |
| facemasks and hand hygiene to prevent influenza transmission in households: a cluster randomized trial. | few data are available about the effectiveness of nonpharmaceutical interventions for preventing influenza virus transmission. | 2009 | 19652172 |
| cultural shift towards sustainability in the construction industry of hong kong. | sustainable development is forward-looking; it is a continuous mission for future developments of human society. a genuinely sustainable society is one that initiates developments in sustainable ways. the development of a genuinely sustainable society is supported by its citizens who think and act according to a recognized code of conduct - the sustainable culture. similar to other forms of culture, sustainable culture of a society is not static, but changes over time. the changes found in a sus ... | 2009 | 19643527 |
| incidence of common respiratory viral infections related to climate factors in hospitalized children in hong kong. | hong kong has a subtropical climate and an influenza seasonality lying approximately mid-way (march-june) between those of the northern (november-march) and southern (june-september) hemispheres. respiratory syncytial virus (rsv) shares a similar seasonality to that of influenza in hong kong and is another important respiratory infection of childhood. daily virus incidence data from public hospitals in hong kong's new territory east cluster, together with hong kong climate data were obtained for ... | 2010 | 19631018 |
| epidemiologic risk profile of infection with different groups of human papillomaviruses. | this study identified the age-specific prevalence and epidemiologic risk profile for infection with different groups and species of human papillomaviruses (hpv). structured interview and hpv testing were conducted for 2,604 chinese women self-referred for cervical screening. independent risk factors for infection were identified by multiple logistic regressions. overall, a major peak of hpv infection was observed at women aged 26-30 years, and a minor peak at 46-55 years. this pattern was observ ... | 2009 | 19623668 |
| cost-effectiveness analysis of influenza and pneumococcal vaccination for hong kong elderly in long-term care facilities. | to compare cost and quality-adjusted life-years (qalys) gained by influenza vaccination with or without pneumococcal vaccination in the elderly living in long-term care facilities (ltcfs). | 2009 | 19608558 |
| widespread public misconception in the early phase of the h1n1 influenza epidemic. | to investigate the community responses and preparedness for a possible epidemic of h1n1 influenza in hong kong shortly after an imported case was confirmed. | 2009 | 19592114 |
| polymorphisms of the estrogen receptor alpha (esr1) gene and the risk of alzheimer's disease in a southern chinese community. | alzheimer's disease (ad) is a neurodegenerative disease with a higher prevalence in women. expression of estrogen receptor 1 (esr1) gene has been identified throughout the brain. owing to the putative neuroprotective effects of estrogen, estrogen receptor gene is a potential candidate modulating the development of ad. preliminary associations between two polymorphisms of esr1 (pvuii and xbai) gene and ad have been reported. | 2009 | 19586561 |
| jak2 v617f mutation in myeloid neoplasms with 3q21 and 3q26 abnormalities in chinese patients. | 2009 | 19562620 | |
| jak2 v617f mutation is associated with 5q- syndrome in chinese. | jak2 v617f mutation is mostly seen in bcr-abli negative myeloproliferative neoplasms. among other myeloid neoplasms, it occurs with remarkably high frequency in refractory anemia with ring sideroblasts associated with marked thrombocytosis, a group of myeloid neoplasms with both dysplastic and proliferative features. it has also been reported in occasional cases of myelodysplastic syndrome with isolated del(5q), often with a diagnosis of refractory cytopenia with multilineage dysplasia. we perfo ... | 2009 | 19562618 |
| risk assessment of pcdd/fs levels in human tissues related to major food items based on chemical analyses and micro-erod assay. | nine groups of food items (freshwater fish, marine fish, pork, chicken, chicken eggs, leafy, non-leafy vegetables, rice and flour) and three types of human samples (human milk, maternal serum and cord serum) were collected for the analysis of pcdd/fs. results of chemical analysis revealed pcdd/fs concentrations (pg g(-1) fat) in the following ascending order: pork (0.289 pg g(-1) fat), grass carp (ctenopharyngodon idellus) (freshwater fish) (0.407), golden thread (nemipterus virgatus) (marine fi ... | 2009 | 19535140 |
| oseltamivir- and amantadine-resistant influenza viruses a (h1n1). | surveillance of amantadine and oseltamivir resistance among influenza viruses was begun in hong kong in 2006. in 2008, while both a/brisbane/59/2007-like and a/hong kong/2652/2006-like viruses (h1n1) were cocirculating, we detected amantadine and oseltamivir resistance among a/hong kong/2652/2006-like viruses (h1n1), caused by genetic reassortment or spontaneous mutation. | 2009 | 19523305 |
| hong kong enrolled nurses' perceptions of spirituality and spiritual care. | to explore hong kong nurses' perceptions of spirituality and spiritual care, and to investigate the relationship between their perceptions and their demographic characteristics. | 2008 | 19522951 |
| occult respiratory viral infections in coronial autopsies: a pilot project. | 2009 | 19509431 | |
| distribution of human papillomavirus types in cervical cancers in hong kong: current situation and changes over the last decades. | human papillomavirus (hpv) type distribution among cervical cancers and its possible changes over time are key issues that determine the cost-effectiveness of hpv vaccines. cervical cancers diagnosed during 3 periods (1997-2007, n = 280; 1984-1986, n = 74; 1972-1973, n = 81) in hong kong were examined for hpv type distribution using sensitive broad-catching methods. the results showed a variation in hpv distribution between histological groups. among cervical squamous cell carcinoma (scc) cases ... | 2009 | 19507252 |
| implantation of a breathing pacemaker in a tetraplegic patient in hong kong. | a 38-year-old man had been tetraplegic and ventilator-dependent after sustaining a traumatic cervical spine fracture at the c1/c2 level in 1991, at the age of 22 years. he had been bedbound and mechanically ventilated since then. a multidisciplinary management team approached him in 2003 and helped him to become ambulatory and independent in his daily activities of living. we successfully implanted the diaphragm pacing stimulation system in this patient in 2004. diaphragm pacing by phrenic nerve ... | 2009 | 19494383 |
| confirmation of the first hong kong case of human infection by novel swine origin influenza a (h1n1) virus diagnosed using ultrarapid, real-time reverse transcriptase pcr. | 2009 | 19474268 | |
| a review on human influenza a h5n1 infections in hong kong. | avian influenza a h5n1 remains the most threatening virus that may cause another devastating pandemic in the foreseeable future. in 1997, hong kong was the first place to detect human infections due to this virus originated from birds. the experience and lessons learnt provide important information for controlling further outbreaks caused by avian influenza viruses. | 2009 | 19471863 |
| multidrug-resistant genotype (abcb1) and seizure recurrence in newly treated epilepsy: data from international pharmacogenetic cohorts. | the association between a specific polymorphism (3435c>t) in the abcb1 gene, coding for the membrane drug transporter p-glycoprotein (pgp), and pharmacoresistance to seizure control is controversial. studies have been limited by multiple drug use, chronic cohorts with varying definitions, and retrospective clinical data. herein we examine the relationship of this polymorphism with seizure recurrence in three independent international cohorts of patients newly treated for epilepsy. | 2009 | 19453704 |
| a study of the health and economic effects of influenza-like illness on the working population under different working environments of a large corporation in hong kong. | the incidence, health and economic impacts of influenza-like illness (ili) among the working population in hong kong had never been studied. due to the nature of the disease, ilis can have a significant impact on the operation of a corporation in terms of loss of productivity and reduced work performance. the present study was undertaken to determine the health and economic impacts of ilis under different environmental conditions on the working population of a large corporation. | 2008 | 19450073 |
| media reporting of the emergence of the 1968 influenza pandemic in hong kong: implications for modern-day situational awareness. | we investigated local media reporting during the emergence of influenza a/hong kong/68 in hong kong to understand how indolent social awareness contributed to delays in warning of the pandemic. | 2009 | 19440155 |
| multilevel analysis of hiv related risk behaviors among heroin users in a low prevalence community. | injecting drug users (idu) are at increased risk of human immunodeficiency virus (hiv) infection. their hiv prevalence however varies from place to place and may not be directly linked with the level of individual risk. this study explores the relative importance of individual and community level characteristics in the practice of hiv-related risk behaviors in idu in hong kong where the hiv prevalence has remained low at below 1%. | 2009 | 19435512 |
| the use of muscle burden in rabbitfish siganus oramin for monitoring polycyclic aromatic hydrocarbons and polychlorinated biphenyls in victoria harbour, hong kong and potential human health risk. | muscle concentrations of polycyclic aromatic hydrocarbons (pahs) and polychlorinated biphenyls (pcbs) were determined in rabbitfish siganus oramin collected from victoria harbour and its vicinity, hong kong from 2004 to 2007. spatially, relatively higher levels of [summation operator]pah (1.05-4.26 microg g(-1)) and [summation operator]pcb (45.1-76.9 ng g(-1)) were determined in the central and western sites inside the harbour. temporally, upward trend of [summation operator]pah, accompanied wit ... | 2009 | 19406454 |
| genotype distribution and sequence variation of hepatitis e virus, hong kong. | most acute cases of infection with hepatitis e virus (hev) in hong kong were autochthonous, sporadic, and occurred in older adults. all except 1 isolate belonged to genotype 4; most were phylogenetically related to swine isolates. the epidemiology is similar to that in industrialized countries, where zoonosis is the major source of hev infection in humans. | 2009 | 19402972 |
| molecular epidemiology of hepatitis e virus in hong kong. | hepatitis e virus (hev) is one of the major causes of acute and self-limiting hepatitis in human. in hong kong, the number of notifications increased from 26 to 62 from year 2001 to 2007. this study describes the molecular epidemiology of hev in hong kong in order to determine the movement and distribution of hev. hev in 171 serum samples from hev igm positive cases from year 2001 to 2007 were amplified using rt-pcr and subjected to nucleotide sequencing. phylogenetic analysis showed 162 of 171 ... | 2009 | 19382265 |
| spatial working memory maintenance: does attention play a role? a visual search study. | recent studies have proposed that a common mechanism may underlie spatial attention and spatial working memory. one proposal is that spatial working memory is maintained by attention-based rehearsal [awh, e., jonides, j., & reuter-lorenz, p. a. (1998). rehearsal in spatial working memory. journal of experimental psychology: human perception and performance, 24(3), 780-790], and so a spatial attention shift during the retention interval of a spatial location should impair its memory performance. ... | 2009 | 19362280 |
| association of bank1 and tnfsf4 with systemic lupus erythematosus in hong kong chinese. | systemic lupus erythematosus (sle) is a prototypic autoimmune disease with complex genetic inheritance. recently, single nucleotide polymorphisms (snps) in bank1 and tnfsf4 have been shown to be associated with sle in caucasian populations, but it is not known whether they are also involved in the disease in other ethnic groups. recent data from our genome-wide association study (gwas) for 314 sle cases and 920 controls collected in hong kong identified snps in and around bank1 and tnfsf4 to be ... | 2009 | 19357697 |
| examination of seroprevalence of coronavirus hku1 infection with s protein-based elisa and neutralization assay against viral spike pseudotyped virus. | human coronavirus hku1 (hcov-hku1) is a recently identified coronavirus with a global distribution and known to cause mainly respiratory infections. | 2009 | 19342289 |
| medians and correction factors for biochemical and ultrasound markers in chinese women undergoing first-trimester screening for trisomy 21. | to establish normative values and distribution parameters of first-trimester maternal serum free beta-human chorionic gonadotropin (beta-hcg), pregnancy-associated plasma protein-a (papp-a) and fetal nuchal translucency (nt) thickness in chinese women and to examine the effects of covariates on their levels. | 2009 | 19306471 |
| attitudes of chinese couples in hong kong regarding using preimplantation genetic diagnosis (pgd) and human leukocyte antigens (hla) typing to conceive a 'saviour child'. | to investigate hong kong couples' attitudes and concerns about using preimplantation genetic diagnosis (pgd) and human leukocyte antigens (hla) typing to conceive a disease-free and tissue-compatible 'saviour child (sc)' to save an afflicted sibling. | 2009 | 19294755 |
| itgam is associated with disease susceptibility and renal nephritis of systemic lupus erythematosus in hong kong chinese and thai. | itgam was recently found to be associated with systemic lupus erythematosus (sle) in populations of not only european ancestry, but also in hispanic- and african-americans, mexicans and colombians. the risk alleles in the gene, however, were found to be monomorphic in two asian populations examined: japanese and korean. in this study, using a collection of 910 sle patients and 2360 controls from chinese living in hong kong, analyzed by both genome-wide association and direct sequencing, we confi ... | 2009 | 19286673 |
| estimation of the serial interval of influenza. | : estimates of the clinical-onset serial interval of human influenza infection (time between onset of symptoms in an index case and a secondary case) are used to inform public health policy and to construct mathematical models of influenza transmission. we estimate the serial interval of laboratory-confirmed influenza transmission in households. | 2009 | 19279492 |
| antiviral constituents against respiratory viruses from mikania micrantha. | phytochemical investigation of the dried aerial parts of mikania micrantha led to the isolation of a new sesquiterpene, 3beta-acetoxy-1,10-epoxy-4-germacrene-12,8;15,6-diolide (1), along with six known constituents: 1,10-epoxy-4-germacrene-12,8;15,6-diolide (2), dihydromikanolide (3), potassium mikanin 3-sulfate (4), mikanin (5), alpinetin (6), and ergosta-7,22-dien-3beta-ol (7). their structures were elucidated by spectroscopic methods, and the molecular structures and stereochemistry of sesqui ... | 2009 | 19267453 |
| duty to care. | the potential threat of a pandemic influenza outbreak has placed emergency preparedness in the health care spotlight. hospitals are increasingly gearing up readiness plans in preparation. most of these plans are related to the implementation of protocols and stockpiling of supplies, medications, and equipment. these plans are dependent on staff for implementation, but will nurses' duty to care for patients outweigh their competing obligations to their families and the risk of their own exposure? | 2009 | 19263924 |
| clinical and molecular epidemiology of human parainfluenza virus 4 infections in hong kong: subtype 4b as common as subtype 4a. | in this 1-year study, 35 (1.2%) of 2,912 nasopharyngeal aspirates were positive for human parainfluenza virus 4 (hpiv4) by reverse transcription-pcr. patients with hpiv4 infection were mainly young children and immunocompromised adults. in contrast to the reported predominance of hpiv4a infection, molecular subtyping revealed that 15 (44%) cases were caused by hpiv4b. | 2009 | 19261793 |
| environmental surveillance for laribacter hongkongensis, a diarrhoeal pathogen discovered in hong kong. | 1. laribacter hongkongensis was isolated from the midguts and hindguts of 86 (24%) of 360 freshwater fish from retail markets, including grass carp (60%), bighead carp (53%), mud carp (25%), and large-mouth bass (5%). 2. this study is the first to demonstrate the presence of l hongkongensis in natural water environments, with the bacterium being isolated from the waters of six reservoirs, with higher recovery rates in summer and during days of higher water and ambient temperatures. 3. molecular ... | 2009 | 19258631 |
| acceptability of human papillomavirus vaccination among chinese women: concerns and implications. | to explore chinese women's perceptions of human papillomavirus (hpv) vaccination and their intention to be vaccinated. | 2009 | 19250361 |
| prenatal influenza exposure and delivery complications: implications for the development of schizophrenia. | this study assessed prenatal influenza exposure in relation to pregnancy complications and delivery complications. participants of this study consisted of a community sample of all mothers of 1,795 children who were a birth cohort recruited at age 3 in a prospective longitudinal project in mauritius. the onset of the 1968-1972 a2/hong kong influenza epidemic in january 1970 was established from officially published death rates and newspaper records. data on pregnancy and delivery complications w ... | 2007 | 19241651 |
| a comparison of aluminum levels in tea products from hong kong markets and in varieties of tea plants from hong kong and india. | this study project aimed to investigate the concentrations of aluminum (al) in tea products available in hong kong markets. tea samples consisting of 47 different tea bags and 28 samples of tea leaves were analysed for concentrations of al. all tea samples released al (0.70-5.93 mg l(-1)) during a standard infusion period. in comparison to the joint fao/who provisional tolerable weekly intake guideline of 7 mg al kg(-1) body weight, it was concluded that tea made with these tea leaves will not i ... | 2009 | 19230955 |
| population differences in sle susceptibility genes: stat4 and blk, but not pxk, are associated with systemic lupus erythematosus in hong kong chinese. | in this study, we compared the association of several newly discovered susceptibility genes for systemic lupus erythematosus (sle) between populations of european origin and two asian populations. using 910 sle patients and 1440 healthy controls from chinese living in hong kong, and 278 sle patients and 383 controls in thailand, we studied association of stat4, blk and pxk with the disease. our data confirmed association of stat4 (rs7574865, odds ratio (or) =1.71, p=3.55 x 10(-23)) and blk (rs13 ... | 2009 | 19225526 |
| chromosomal anomalies and y-microdeletions among chinese subfertile men in hong kong. | to report the type and frequency of chromosomal anomalies and y-microdeletions among hong kong chinese subfertile men with sperm concentrations lower than 5 million/ml. design. retrospective study. | 2009 | 19197094 |
| preventing healthcare workers from acquiring influenza. | our survey of 133 on-duty medical ward nurses showed that, during peak influenza season, 30 (23%) developed an influenza-like illness, despite wearing a mask at work. suboptimal adherence to standard precautions, such as the use of a face shield (odds ratio, 3.56) during high-risk procedures, and failure to receive influenza vaccination (odds ratio, 4.82) were independent risk factors, adjusted for household contacts. | 2009 | 19193127 |
| sources of information and health beliefs related to sars and avian influenza among chinese communities in the united kingdom and the netherlands, compared to the general population in these countries. | ethnic minorities in europe such as the chinese may need a special strategy with regard to risk communication about emerging infectious diseases. to engage them in precautionary actions, it is important to know their information sources, knowledge, and health beliefs. | 2009 | 19184453 |
| a qualitative study of patients' views on quality of primary care consultations in hong kong and comparison with the uk care measure. | patients' priorities and views on quality care are well-documented in western countries but there is a dearth of research in this area in the east. the aim of the present study was to explore chinese patients' views on quality of primary care consultations in hong kong and to compare these with the items in the care measure (a process measure of consultation quality widely used in the uk) in order to assess the potential utility of the care measure in a chinese population. | 2009 | 19173724 |
| concentrations of polycyclic aromatic hydrocarbons and polychlorinated biphenyls in green-lipped mussel perna viridis from victoria harbour, hong kong and possible human health risk. | 2009 | 19155024 | |
| effects of magnification methods and magnifier shapes on visual inspection. | this study investigated the effectiveness of the novel differential linear and differential nonlinear magnification methods, and the effects of magnifier shape and magnification power on visual search performance. with the differential magnification, objects that were more peripheral were scaled at a level higher than those in the vicinity of fixation. it was hypothesized that 1) owing to the ineffectiveness of scaling stimulus in the vicinity of fixation, the differential magnification methods ... | 2009 | 19121515 |
| an experience on wheelchair bank management. | in this article, we described the wheelchair bank program at a local hospital and our experiences in managing the service over the past 10 years from 1996 to 2005. this article also reported statistical information related to the acquisitions of wheelchairs and adaptive components, including body support and pressure relief systems. the cost benefit of recycling seating and mobility equipments for use by children with neuromuscular diseases was revealed. with the reference of the reported data, ... | 2008 | 19117190 |
| evaluation of loxl1 polymorphisms in primary open-angle glaucoma in southern and northern chinese. | the lysyl oxidase-like protein 1 (loxl1) gene is strongly associated with exfoliation glaucoma, which is very rare in the chinese population. the implicated loxl1 polymorphisms have not been associated with primary open-angle glaucoma (poag). in this study, we investigated three of the loxl1 polymorphisms in poag in a southern chinese population of hong kong and northern chinese from beijing. | 2008 | 19098994 |
| methicillin-resistant commensal staphylococci in healthy dogs as a potential zoonotic reservoir for community-acquired antibiotic resistance. | beta-lactam-resistant staphylococci evolved due to widespread nosocomial antibiotic use during the twentieth century, but the last decade has seen the emergence of genotypically distinct resistant bacteria outside hospitals, such as community-acquired methicillin-resistant staphylococcus aureus (ca-mrsa). this changing epidemiology suggests that mechanisms other than direct antibiotic selection could be involved in the spread of bacterial resistance. here we report a 17% prevalence of methicilli ... | 2009 | 19073283 |
| antiviral activities of extracts from hong kong seaweeds. | we extracted six hong kong brown seaweed species with hot water for their antiviral properties. the cytotoxicity and antiviral activity of these extracts were tested by mtt [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenlytetrezolium bromide] method, cytopathic effect reduction assay, and plaque reduction assay. the antiviral effect was further determined by flow cytometric analysis. the results showed that most of these extracts inhibited the propagation of herpes simplex virus types 1 and 2 (hsv-1 an ... | 2008 | 19067465 |
| melamine-tainted milk product (mtmp) renal stone outbreak in humans. | 2008 | 19060339 | |
| identification of viral and atypical bacterial pathogens in children hospitalized with acute respiratory infections in hong kong by multiplex pcr assays. | acute respiratory tract infection is a leading cause of hospital admission of children. this study used a broad capture, rapid and sensitive method (multiplex pcr assay) to detect 20 different respiratory pathogens including influenza a subtypes h1, h3, and h5; influenza b; parainfluenza types 1, 2, 3, and 4; respiratory syncytial virus (rsv) groups a and b; adenoviruses; human rhinoviruses; enteroviruses; human metapneumoviruses; human coronaviruses oc43, 229e, and sars-cov; chlamydophila pneum ... | 2009 | 19031443 |
| epidemiology of human papillomavirus infection and cervical cancer and future perspectives in hong kong, singapore and taiwan. | hong kong, singapore and taiwan are three island states that are newly emerged affluent economic areas in asia. the majority of the populations are ethnically chinese with a total population of 6.98, 4.5 and 23 million, respectively. cervical cancer has been declining over the last thirty years in all three states and is largely attributable to widespread opportunistic cervical cancer screening. the age-standardized incidence rates of cervical cancer are 9.6 per 100,000 women in hong kong in 200 ... | 2008 | 18945415 |
| chinese widowers' self-perception of growth: an exploratory study. | presence of growth after traumatic events was introduced to the academic community about a decade ago (tedeschi & calhoun, 1995). from the conventionally neglected perspective of chinese widowers, this paper reports seventeen chinese widowers' views on growth after conjugal loss. findings seem to suggest that chinese widowers would define growth as human learning, a definition probably influenced by confucian teachings. furthermore, contrary to claims made by tedeschi and calhoun (2004), it was ... | 2007 | 18928081 |
| the genetic variability of mdr1 c3435t polymorphisms in four southern chinese populations. | to investigate the genetic variability of multiple drug resistant 1 (mdr1) gene c3435t polymorphism in four southern chinese populations. | 2009 | 18926661 |
| chinese older people in hong kong: health beliefs about influenza vaccination. | a health belief survey of 70 community-dwelling chinese older people was carried out in five general outpatient clinics in the kowloon east hospital cluster of hong kong. subjects were asked about their susceptibility to influenza, their perceptions of its severity, and benefits of and barriers to vaccination. beliefs in their own good health, the effectiveness of cultural measures adopted to prevent influenza and its curability may be among the reasons why those who decline the vaccination thou ... | 2008 | 18853548 |
| clinical and economic impact of an antibiotics stewardship programme in a regional hospital in hong kong. | inappropriate use of antibiotics is one of the important factors attributing to emergence of drug-resistant pathogens. infection with multidrug-resistant pathogens adversely affects quality of medical care. | 2008 | 18842981 |
| the first nocturnal home haemodialysis patient in hong kong. | we report our experience of the first use of nocturnal home haemodialysis in hong kong. the patient, a 40-year-old man with end-stage renal failure, was recruited into the nocturnal home haemodialysis programme at princess margaret hospital in 2006. he received haemodialysis at home on alternate nights (3.5 sessions per week) for 5.5 to 6 hours per session. after 1 year of nocturnal home haemodialysis, his recombinant human erythropoietin requirement had been reduced by more than 50%. his serum ... | 2008 | 18840912 |
| [study on characterization of the hemagglutinin gene of avian influenza virus h5n1 subtype originated from the pan pacific regions]. | to understand the gene characterization of hamagglutinin (ha) of aiv h5n1 subtype originated from the pan pacific regions in order to find out its mutation possibility. | 2008 | 18839532 |
| effects of school closures, 2008 winter influenza season, hong kong. | in winter 2008, kindergartens and primary schools in hong kong were closed for 2 weeks after media coverage indicated that 3 children had died, apparently from influenza. we examined prospective influenza surveillance data before, during, and after the closure. we did not find a substantial effect on community transmission. | 2008 | 18826841 |
| identification of an invasion and tumor-suppressing gene, endoglin (eng), silenced by both epigenetic inactivation and allelic loss in esophageal squamous cell carcinoma. | endoglin (eng) has been identified as a candidate tumor-suppressor gene in esophageal squamous cell carcinoma (escc). earlier microcell-mediated chromosome transfer (mmct) studies of chromosome 9 in escc narrowed down a tumor-suppressive critical region to 9q33-34. eng maps to 9q34-qter and encodes a transformation growth factor beta (tgfbeta) superfamily auxiliary receptor. this study aims to identify the potential role for eng in escc development. significant downregulation of eng was detected ... | 2008 | 18798555 |
| perceptions related to bird-to-human avian influenza, influenza vaccination, and use of face mask. | h5n1 avian influenza may become pandemic in humans in the near future. according to the severe acute respiratory syndrome (sars) experience, anticipation of the pandemic may have impact on behaviors related to influenza vaccination (iv) and relevant public health behaviors such as wearing a face mask when having influenza-like-illnesses (ili), which would play an important role in the control of human avian influenza outbreaks. this paper investigated the prevalence and factors related to iv upt ... | 2008 | 18795229 |
| a case series of accidental ingestion of hand warmer. | the use of hand warmers in hong kong during cold weather has become increasingly popular. iron powder is one of the ingredients. we report the first cases of ingestion of hand warmer contents. care reports: four elderly patients ingested the contents of hand warmers. all had no or mild symptoms, one had radiopaque particles in the stomach, two showed transiently increased serum iron concentrations (within the reference range), and all recovered with only supportive care. | 2008 | 18787994 |
| functional polymorphisms in the brca1 promoter influence transcription and are associated with decreased risk for breast cancer in chinese women. | the brca1 gene is an important breast-cancer susceptibility gene. promoter polymorphisms can alter the binding affinity of transcription factors, changing transcriptional activity and may affect susceptibility to disease. | 2009 | 18782836 |
| familial nasopharyngeal carcinoma in hong kong: epidemiology and implication in screening. | the pathogenetic mechanism of nasopharyngeal carcinoma (npc) is still unclear. its familial aggregation, on the other hand, has been well documented by many epidemiological studies. the objective of this study was to evaluate the clinical characteristics of familial npc in an endemic region. between march 1994 and november 2005, 1,202 consecutive patients were treated at our institution. patients were divided into 2 groups according to their family history: group 1 had at least one first-degree ... | 2009 | 18726711 |
| twenty-seven students ill in suspected flu outbreaks in hong kong. | 2008 | 18701043 | |
| risk factors associated with human immunodeficiency virus (hiv) infection among attendees of public sexually transmitted infection clinics in hong kong: implications for hiv prevention. | to examine the risk factors for human immunodeficiency virus (hiv) transmission among attendees of public sexually transmitted infection clinics in hong kong. | 2008 | 18685157 |
| avian influenza a/h5n1 virus: management in human and bird. | 2008 | 18685155 | |
| [asia: avian influenza h5n1]. | the emergence of the first human cases of avian influenza in hong kong in 1997 has raised fears of a new pandemic originating from the asian continent. despite unprecedented international mobilization, first to stop then to limit its diffusion, the highly pathogenic avian virus a/h5n1 has successfully spread in asia, europe and africa by successive epizootic outbreaks affecting migratory birds and poultry, transmission from animals to humans is uncommon but severe with a fatality rate exceeding ... | 2008 | 18681218 |
| quinolone resistance and correlation to other antimicrobial resistances in faecal isolates of escherichia coli in hong kong. | in an attempt to assess the level of quinolone resistance and its association with other antimicrobial resistance in faecal escherichia coli isolated from routine outpatient specimens in hong kong, ciprofloxacin-supplemented macconkey agar was used to screen for resistant isolates. antimicrobial susceptibility testing of the isolates was done by vitek 2 and previous amplification-based methods were employed to characterize the genetic determinants behind some of the resistance phenotypes. one hu ... | 2008 | 18667817 |
| seasonality of influenza a(h3n2) virus: a hong kong perspective (1997-2006). | the underlying basis for the seasonality of influenza a viruses is still uncertain. phylogenetic studies investigated this phenomenon but have lacked sequences from more subtropical and tropical regions, particularly from southeast asia. | 2008 | 18648550 |
| ddt levels in human milk in hong kong, 2001-02. | high levels of p,p'-ddt were detected in hong kong breast milk sampled in 1976 and 1985. monitoring ddt levels in human breast milk in this region is important to identify trends in exposure. as part of the 2002-03 who/euro coordinated exposure study, the concentrations of ddt and its metabolites were determined in 10 pooled milk samples classified by geographic origin and dietary history, comprising milk samples from 238 primiparous mothers giving birth in hong kong. analysis was performed by g ... | 2008 | 18640700 |
| identification of novel porcine and bovine parvoviruses closely related to human parvovirus 4. | human parvovirus 4 (parv4), a recently discovered parvovirus found exclusively in human plasma and liver tissue, was considered phylogenetically distinct from other parvoviruses. here, we report the discovery of two novel parvoviruses closely related to parv4, porcine hokovirus (phov) and bovine hokovirus (bhov), from porcine and bovine samples in hong kong. their nearly full-length sequences were also analysed. parv4-like viruses were detected by pcr among 44.4 % (148/333) of porcine samples (i ... | 2008 | 18632954 |
| avian influenza and pandemic influenza preparedness in hong kong. | avian influenza a h5n1 continues to be a major threat to global public health as it is a likely candidate for the next influenza pandemic. to protect public health and avert potential disruption to the economy, the hong kong special administrative region government has committed substantial effort in preparedness for avian and pandemic influenza. public health infrastructures for emerging infectious diseases have been developed to enhance command, control and coordination of emergency response. ... | 2008 | 18618061 |
| optimizing use of multistream influenza sentinel surveillance data. | we applied time-series methods to multivariate sentinel surveillance data recorded in hong kong during 1998-2007. our study demonstrates that simultaneous monitoring of multiple streams of influenza surveillance data can improve the accuracy and timeliness of alerts compared with monitoring of aggregate data or of any single stream alone. | 2008 | 18598647 |
| molecular epidemiology demonstrated three emerging clusters of human immunodeficiency virus type 1 subtype b infection in hong kong. | we conducted a molecular epidemiological study on newly diagnosed human immunodeficiency virus type 1 (hiv-1)-infected patients in hong kong to identify the epidemiological linkage of hiv-1 infection in the locality. reverse transcription polymerase chain reaction (rt-pcr) for hiv-1 was performed on newly diagnosed hiv-1-positive sera collected from january 2002 to december 2006. pcr products correspond to the env c2v3v4 region and gag p17/p24 junction of the hiv-1 genome were nucleotide sequenc ... | 2008 | 18593342 |
| emotional reactions of anger and shame to the norm violation characterizing episodes of interpersonal harm. | norms are the socially shared restraints by which human behaviour is regulated. when applied to events involving interpersonal harm, the perceived level of norm violation by a perpetrator will lead to a target's emotional reactions of both anger and shame, with such processes mediated by the target's judgments of his or her loss of face arising from the episode, the perpetrator's intent to harm, and the blame ascribed to the perpetrator. structural equation modelling (sem) confirmed this set of ... | 2009 | 18573225 |
| extended parallel process model and h5n1 influenza virus. | this study integrated the extended parallel process model and forewarning cues to assess the promotion of preventive measures against the h5n1 influenza virus, a significant health threat that affects asia, europe, and the usa. there are two types of forewarning, (1) telling the audience that they will hear messages intended to persuade them and (2) telling the audience the topic and stance of the impending persuasive message. analysis of ratings by 265 undergraduates indicated that forewarnings ... | 2008 | 18567223 |
| novel astroviruses in insectivorous bats. | bats are increasingly recognized to harbor a wide range of viruses, and in most instances these viruses appear to establish long-term persistence in these animals. they are the reservoir of a number of human zoonotic diseases including nipah, ebola, and severe acute respiratory syndrome. we report the identification of novel groups of astroviruses in apparently healthy insectivorous bats found in hong kong, in particular, bats belonging to the genera miniopterus and myotis. astroviruses are impo ... | 2008 | 18550669 |
| evaluating narrative pedagogy in nursing education in hong kong. | this column provides a report of the effectiveness of a nursing program in hong kong that used narrative pedagogy. the comments of 12 recent graduates from a postgraduate baccalaureate nursing degree program who were willing to participate in a series of focus group meetings were included. the findings show that nursing education based on a human science paradigm helped form the professional nursing identity of the graduates, as they continued retelling, reliving, and reflecting on their caring ... | 2008 | 18544790 |
| warming earth could face new flu, disease threats. | 2008 | 18541678 | |
| lrrk2 gly2385arg mutation and clinical features in a chinese population with early-onset parkinson's disease compared to late-onset patients. | the frequency of lrrk2 gly2385arg mutation in hong kong chinese with early-onset (age < or =45 years) parkinson's disease was identified and compared with late-onset patients (age >50 years) and controls. the mutation prevalence were 8.8, 8.3, and 0% for early-onset, late-onset, and controls, respectively. the mean age of onset among lrrk2 g2385r carriers was 42.7 years old for early-onset compared to 74.3 for late-onset patients. lrrk2 g2385r mutation appears to be as prevalent among early-onse ... | 2008 | 18523722 |