Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
|---|
| analysis of a 43-kda glycoprotein from the intracellular parasitic nematode trichinella spiralis. | the l1 larvae of the parasitic nematode trichinella spiralis invade skeletal muscle and initiate a process that has been interpreted to represent skeletal muscle dedifferentiation. in this process, the infected region of the muscle cell is converted into a unique structure, called the nurse cell. the nematode t. spiralis can survive for tens of years within the cytoplasm of the nurse cell and secretes proteins into the cytoplasm that are believed to play a role in mediating the nurse cell format ... | 1992 | 1382055 |
| increased levels of substance p in the myenteric plexus of trichinella-infected rats. | changes in immunoreactive substance p concentrations were investigated in longitudinal muscle-myenteric plexus preparations from the inflamed jejunum of trichinella spiralis-infected rats. the substance p concentration increased within 2 days of infection and increased fivefold by day 6; in contrast, there was no significant increase in substance p in the noninflamed ileum. in vitro exposure of preparations from infected rats to scorpion venom reduced substance p levels by 88%. in addition, no i ... | 1992 | 1375178 |
| specificity of affinity-purified trichinella spiralis antigens. | an affinity-purified fraction (apf) was obtained by passing crude somatic antigens of trichinella spiralis muscle larvae through an affi-gel 10 column coupled with anti-trichuris suis igg. the fraction contained seven antigens with molecular weights ranging from 28 to 55 kda. when tested with antiserum against other common nematodes of pigs from china, the apf was found to be markedly more specific than s3 antigens (prepared by a combination of cell fractionation and differential centrifugation ... | 1992 | 1373256 |
| [soluble metabolic antigens of trichinella spiralis: their isolation and characteristics]. | cultivation of trichinella muscular larvae, purified by centrifugation in 20 ... 50% saccharose density gradient, in protein--free nutrient media at a dosage of 3.5-.10(3) lar./ml in the presence of insulin has made it possible to obtain a soluble antigen of trichinella. it has been shown by means of electrophoresis in polyacrylamide gel that the soluble (secretory-excretory) antigen has three protein fractions while the somatic trichinella antigen has 18 fractions. it has been shown that the so ... | 1992 | 1364527 |
| characterization of cholinesterases from the parasitic nematode trichinella spiralis. | 1. trichinella cholinesterases occur in multiple molecular forms which differ in size, kinetics, activity with butyrylthiocholine, and effects of inhibitors. 2. the 5.3 and 13s forms identified in trichinella extracts are also found in c. elegans and other nematodes but the 7s form which occurs in other nematodes was absent from trichinella detergent extracts. differences in kinetic and inhibition properties among nematode species were also evident. 3. the level of cholinesterases in excretory/s ... | 1992 | 1360365 |
| influence of resistant and susceptible genotype, il-1, and lymphoid organ on trichinella spiralis-induced cytokine secretion. | the relative importance of cell-mediated inflammatory responses and antibody-mediated responses in controlling parasitic helminth infection is debated. to study the relationship between these responses and resistance or susceptibility to primary trichinella spiralis infection, we infected resistant akr mice and susceptible b10.br mice and analyzed the lymphokines il-2, ifn-gamma, and il-5 produced by their t cells as a function of time and lymphoid organ. il-2-secretors occurred maximally betwee ... | 1992 | 1353100 |
| recognition of trichinella spiralis muscle larvae antigens by sera from human infected with this parasite and its potential use in diagnosis. | human antibody response to total soluble extract of trichinella spiralis muscle larvae (tse) was analyzed by western blot. the most frequently recognized antigens had molecular weights of 96, 67, 63, 60, 55 and 47 kda. an antigenic fraction containing two peptides with m.w. of 43, 47 kda from the parasite (p43, 47 ts l1) was isolated by elution from polyacrylamide gel slabs. it was used as antigen in an elisa test and compared to that of tse. serum samples from 51 symptomatic trichinellosis pati ... | 1992 | 1345318 |
| [susceptibility and the immune response to trichinella spiralis infection]. | the aim of this study was to assess a possible association between parameters of immune response and susceptibility/resistance to t. spiralis infection. the immune response to t. spiralis was monitored in two inbred strains of mice (balb/c and c57bl/6), as well as in the most important natural host--swine, by analysing the changes in main lymphocyte populations, the appearance of specific antibodies and worm burden recovery. in the murine model, the lower level of muscle larvae worm burden recov ... | 1992 | 1340488 |
| the significance of the "lung phase" in host-helminth relations. | many helminth infections have a "lung phase" whose significance considering the host-parasite relations has not yet been clarified. in some nematode infections larvae must pass through the lungs, in others adult worms live in the respiratory tract, and some others cause tropical pulmonary eosinophilia. some examples of these infections (nippostrongylus brasiliensis, schistosoma mansoni, trichinella spiralis and toxocara canis) are considered to clarify whether this phase of infection is a "pro-h ... | 1992 | 1339975 |
| impaired acetylcholine release in the inflamed rat intestine is t cell independent. | we investigated mechanisms underlying the suppression of [3h]acetylcholine ([3h]ach) release from myenteric plexus-longitudinal muscle preparations of rats infected 6 days previously with trichinella spiralis. there was a 73% suppression of kcl-evoked release of [3h]ach in the jejunum, and a 76% suppression was observed in the worm-free ileum, indicating that the local presence of the parasite in the lumen is not prerequisite for the suppression of ach release from the myenteric plexus. treatmen ... | 1992 | 1325127 |
| [current prevalence of trichinosis in santiago, chile (1992). a study on 500 corpses]. | in august-december 1992, 500 diaphragm muscle samples taken at random from people who were autopsied at the santiago medico-legal service, were submitted to phototrichinoscopy to search for encysted larvae of trichinella spiralis. for each sample seven small pieces were examined. three hundred and eighty nine (77.8%) cadavers corresponded to males and one hundred and eleven (22.2%) to females. ages ranged from 1 to 90 years. ten (2.0%) of the individuals examined resulted positive, the higher fr ... | 1992 | 1307006 |
| [the role of the nucleus in the mechanism of transformation of muscle after infection by trichinella spiralis larvae. iii. morphometric analysis of the functional transformation of the muscle cell nucleus after infection]. | morphometric investigations (using the convergence analysis method) of geometric parameters of nuclei and nucleoli of transformed muscle cells were carried in mice 15 days, 30 days and 6 month after infection with t. spiralis larvae. the analysis showed the largest increase of investigated the parameters of 15th day after the infection. the results of morphometric analysis are in agreement with the morphologic, ultrastructural and histochemical observations (published in i and ii part) as for as ... | 1992 | 1299069 |
| trichinellosis in the ussr (1983-1987), tendency to spreading. | 1992 | 1299061 | |
| efficacy of albendazole against trichinella pseudospiralis and trichinella spiralis in mice. | albendazole (smith kline, beecham) in a dose of 20 mg/kg/day was given to b6c3f1 mice exposed to 300 larvae of t. pseudospiralis or t. spiralis. the drug was introduced on days 2, 3 and 4; or 4, 5 and 6; or 18, 19 and 20 after infection. it limited the intensity of intestinal and muscle phases of trichinellosis. given at the stage of maturation of adult forms and production of new-born larvae, the drug caused almost total elimination of both species from the intestines of mice and a decrease in ... | 1992 | 1299060 |
| [influence of nalcrom (sodium cromoglycate) on the course of the intestinal phase of trichinellosis in mice]. | the influence of nalcrom (sodium cromoglycate) on the course of the intestinal phase of trichinellosis in mice was investigated. the animals infected with 200 trichinella spiralis larvae were treated with nalcrom between 7-20 or 3-20 days after infection (d.a.i.). the drug was administered in two doses: 0.6 or 1.7 mg/mouse/day. in the all groups of animals received nalcrom higher number of mast cells and eosinophils than in the control groups was observed. these results are the opposite of those ... | 1992 | 1299059 |
| activity of specific igg, igm and ige antibodies in human trichinellosis. | the activity of igg, igm and ige antibodies to somatic antigen of trichinella spiralis in the sera of patients with trichinellosis at various intervals after infection was examined by means of elisa. mathematical analysis of the dose-response curves was used. elevated level of igg and igm antibodies of relatively high avidity and of rather low ige avidity was documented. amount or avidity of igg antibodies was found to be most useful for the diagnosis of trichinellosis (85% positive results in p ... | 1992 | 1299058 |
| activity of natural killer (nk) cells in the course of experimental trichinellosis in mice. | b6c3f1 mice were infected with 200 or 500 larvae of trichinella spiralis per mouse and pulmonary nk cell-mediated clearance of semisyngeneic tumour cells was determined in vivo on days 10, 20, 30, and 60 after the infection. cytotoxic activity of nk cells in the lungs was substantially elevated on days 20 and 30 after challenge with both "doses" of the parasite. at the same time large granular lymphocytes (lgls) as well as cells expressing surface asialo-gm1 molecules were isolated in elevated n ... | 1992 | 1299057 |
| [influence of cadmium on the course of intestinal and muscular phases in mice infected with trichinella spiralis]. | at the first experiment 20 swiss male mice were infected with 100 larvae and 20 mice with 500 larvae t. spiralis per mouse. two days after infection (d.a.i.) mice orally received 1.5 mg cd (water solution cdcl2) each. 40 mice were infected only t. spiralis as control. at the second experiment muscle larvae used were isolated from mice (from the first experiment) which received cd. 20 mice were infected with 100 larvae and 20-with 500 larvae per mouse. two d.a.i. mice received 1.5 mg cd. mice fro ... | 1992 | 1299056 |
| [a method for acquiring newborn larvae of trichinella spiralis in vitro]. | this paper reports a simple method for acquiring numerous newborn larvae of trichinella spiralis in vitro. adults of t. spiralis, collected from small intestine on rats which were infected with infective larvae separated from mice infected experimentally, were put into tissue culture bottle containing m199. then the bottles were incubated in co2 incubator (37 degrees c, 5% co2) for 15-20h. the newborn larvae were collected by passing through filtration, centrifugation and repeated wash. the resu ... | 1992 | 1298727 |
| [establishment and preliminary application of competitive elisa using monoclonal antibody against trichinella spiralis]. | monoclonal antibody competitive elisa was devised with a highly specific mcab (2g8) against t. spiralis. among 20 rabbits infected with t. spiralis experimentally. 35% (7/20) were positive on the 17th day post infection (pi); 100% positive on the 31st day pi. no cross reaction was found with 29 sera of rabbits infected with other kinds of helminth. the dynamic antibody titer of five infected rabbits sera were studied with this method. the change may be helpful to judge the state of infection. in ... | 1992 | 1298715 |
| [trichinellosis focus resulting from consumption of wild boar meat]. | the focus of trichinellosis was presented comprising 28 patients and resulting from consumption of the wild boar meat. early confirmation of trichinellosis diagnosis in the first case (index case) and an accurate epidemiological analysis established that the patients became infected with trichinella spiralis strain originating from natural environment. a severe clinical course was disclosed in the index case, moderate course of trichinellosis in 11 patients, a mild course in 15 cases and an abor ... | 1992 | 1296244 |
| immunodiagnosis of human trichinellosis using excretory-secretory (es) antigen. | infective first stage larvae of trichinella spiralis were recovered from muscles of laboratory infected mice by digesting the muscles with 1% hc1-1% pepsin and collecting the larvae by modified baerman's method. the larvae were cultivated in a serum-free medium for 18 h. the es antigen obtained from the culture medium was used in an enzyme-linked immunosorbent assay (elisa) for detecting igg antibodies to t. spiralis in serum samples collected from three groups of individuals. the individuals of ... | 1992 | 1293197 |
| an outbreak of trichinosis in lebanon. | in 1982 an outbreak of trichinosis occurred in an area of south lebanon consisting of 4 villages, including 6440 persons. in 267 households, involving 2456 persons, typical clinical signs of trichinella spiralis infection could be recognized among household members. twenty-one of these households, including 193 persons, were randomly chosen for further studies. nearly half of the household members (46%) had clinical symptoms consistent with acute trichinosis. 12 of 16 tested persons had high ant ... | 1992 | 1287937 |
| trichinella spiralis: specificity of es antigens from pre-encysted larvae. | excretory/secretory (es) antigens were obtained by culturing pre-encysted trichinella spiralis larvae which were recovered from muscles of experimentally infected mice 14-15 days postinfection. analyses of these antigens (pel es) with immunoblotting, sds-page and triple antibody elisa showed that they yielded a low sensitivity and specificity when tested with antisera against the common nematodes of chinese pigs. as compared to es antigens from encysted larvae, pel es also contained more low mol ... | 1992 | 1281854 |
| synthesis and characterization of rat interleukin-10 (il-10) cdna clones from the rna of cultured ox8- ox22- thoracic duct t cells. | a cdna of the complete coding region of rat il-10 was cloned and sequenced using rna isolated from a cultured population of thoracic duct t-lymphocytes obtained from trichinella spiralis infected animals. the ox8- ox22-t-helper cells were stimulated in vitro with concanavalin a for 24 hours prior to harvest. reverse transcription of cellular rna was primed with oligo-dt followed by amplification of il-10 specific cdna by polymerase chain reaction with synthetic oligo nucleotide primers chosen fr ... | 1992 | 1280414 |
| an evaluation of the role of carbohydrate epitopes in immunity to trichinella spiralis. | a study is described in which the role of carbohydrate epitopes in the generation of protective immunity to trichinella spiralis was investigated. antigen preparations were treated with increasing molar concentrations of sodium periodate, which is known to degrade carbohydrate moieties by cleaving one side of the hexose ring, and a suitable protocol was established for the selective degradation of carbohydrates with the retention of protein integrity. using excretory/secretory (es) proteins, bot ... | 1992 | 1279505 |
| immunity to primary and challenge infections of trichinella spiralis in mice: a re-examination of conventional parameters. | in young (6- to 8-week-old) nih strain inbred mice expulsion of a primary infection of trichinella spiralis began on day 8 and was virtually complete by day 11-5. in older mice expulsion occurred 1 or 2 days earlier. experience of a primary infection elicited strong immunity to challenge, whether the challenge was given immediately after worm expulsion (day 14) or delayed (day 42). challenge infections were expelled rapidly the majority of worms being lost during the first day. immunity to chall ... | 1976 | 1264489 |
| reliability of elisa (enzyme-linked immunosorbent assay) as control method for the detection of trichinella spiralis infections in naturally infected slaughter pigs. | 1976 | 1263051 | |
| prevalence of trichinella spiralis in the mongoose, human, and swine populations of the virgin islands. | 1976 | 1263030 | |
| [mineral contents of the blood and chemical composition of the muscles of trichinella-infected piglets (author's transl)]. | three piglets of 22 kg were infected each with 10 larvae of trichinella spiralis per g body weight. in the blood plasma the contents of several electrolytes were measured twice per week to day 45 post infection (p.i.). these electrolytes, water, dry matter, lipids, nitrogen and ash contents were assayed on samples of muscles of each animal after they were sacrificed on day 61 p.i. three noninfected piglets served as controls. in blood plasma the contents of na, mg, ca, cu, zn and chloride decrea ... | 1976 | 1258143 |
| immunogenicity of the parenteral stages of trichinella spiralis. | 1976 | 1255373 | |
| reliability of the enzyme-linked immunosorbent assay (elisa) for the serodiagnosis of trichinella spiralis infections in conventionally raised pigs. | an enzyme immunoassay with horse radish peroxidase as marker enzyme for detection of antibodies to trichinella spiralis in pigs is described. in the enzyme-linked immunosorbent assay (elisa) quantitation of specific antibodies is obtained by means of peroxidase labeled anti-species-immunoglobulin in antigen-coated tubes. the enzyme remaining in the tube after washing provides a measure of the amount of specific antibodies in the serum. a crude saline extract of t. spiralis muscle larvae served a ... | 1976 | 1254975 |
| trichinella spiralis: anaphylactic antibody formation and susceptibility in strains of inbred mice. | 1976 | 1253885 | |
| finding of trichinella spiralis in a walrus (odobenus rosmarus l.) in the thule district, northwest greenland. | 1976 | 1250688 | |
| the immune mechanism which expels the intestinal stage of trichinella spiralis from rats. | the immunological response of rats to the intestinal phase of trichinella spiralis was assessed using criteria derived from pervious studies with the nematode nippostrongylus brasiliensis in rats and mice. in adult rats, the duration of infection with either parasite is similar and both infections are prolonged in young and lactating rats. as previously shown with n. brasiliensis, immunity to t. spiralis was transferred to recipients with antiserum or mesenteric lymph node cells from immune dono ... | 1976 | 1248863 |
| trichinosis (trichinella spiralis infestations) in wild animals of the kruger national park. | in africa trichinosis is essentially a disease of wild carnivores. once established in a suilline cycle it becomes a more important threat to man. the results of tests on 8,000 specimens of 20 wildlife species in the kruger national park are discussed and the epizootiology of trichinosis in south africa is briefly reviewed. the first case of trichinosis in an african civet, viverra civetta schreber, 1776, is reported. the confirmed absence of trichinosis in true herbivores is of practical signif ... | 1975 | 1240968 |
| [ultrastructural changes in muscle cells infected with trichinella spiralis]. | 1975 | 1221627 | |
| [interrelations of experimental trichinella spiralis and erysipelothrix insidiosa infection in rats]. | 1975 | 1217543 | |
| [the effect of trichinella spiralis on the susceptibility and antibody production to vaccinia virus]. | trichinella spiralis exerts an immunodepressive effect on production of antihemagglutinins to vaccinia virus in mice, increases the susceptibility to the virus in mice and rabbits. deaths of mice inoculated with vaccine virus and generalization of the vaccination process in rabbits were observed at 33 days of invasion. | 1975 | 1216835 |
| detecting the presence of trichinella spiralis (owen) larvae in animal muscle by automatic data-processing using a digital image transmutator for feeding the data into the computer. | 1975 | 1212544 | |
| failure to confirm reported lethal effect of cytotoxic drugs on encapsulated trichinella spiralis larvae in mice. | 1975 | 1195075 | |
| laboratory study of the fate of trichinella spiralis larvae (owen, 1935) in the body of insects species dermestes lardarius l. | 1975 | 1189449 | |
| elisa (enzyme-linked immunosorbent assay) as preventive and repressive control method for the detection of trichinella spiralis infections in slaughter pigs. | 1975 | 1189447 | |
| the association in mice of intestinal inflammation, elevated levels of phospholipase b, and expulsion of trichinella spiralis. | 1975 | 1189440 | |
| biochemistry of trichinella spiralis. | 1975 | 1189439 | |
| immunobiology of trichinella spiralis. | 1975 | 1189433 | |
| [clinical, epidemiological and parasitological characteristics of human trichinosis caused by synanthropic and wild animals strains of trichinella spiralis]. | 1975 | 1189432 | |
| trichinella spiralis studies in the netherlands. | 1975 | 1189427 | |
| quantitative study of the effect of previous trichinella spiralis infection on sarcoma 180 ascitic tumor formation in mice. | tumor development in ham/icr mice inoculated intraperitoneally with sarcoma 180 (s-180) can be easily quantitated by linear regression analysis of non-destructive measurement of total body mass. this procedure readily separated the postinoculation period into incubation and clinical phases. the former was dependent on s-180 dose, while the latter was not. trichinella spiralis infection 28 days prior to s-180 challenge produced small but statistically significant increases in the length of both t ... | 1975 | 1189027 |
| immunity to trichinella spiralis vi. the specificity of the immune response stimulated by the intestinal stage. | mice were immunized to the intestinal stage of t. spiralis by using infections terminated with methyridine before production of newborn larvae had commenced. the muscle larvae which encysted following a normal complete challenge infection were reduced by 87 and 95% in immunized mice. no statistically significant reduction in a challenge infection of intravenously injected parenteral larvae was produced (8% and 15% actual reduction). previous work has shown that adult worms in a challenge infecti ... | 1975 | 1168664 |
| [effect of trichinella spiralis infection on the development of rauscher leukemia]. | the influence of trichinella spiralis on the course of rausher leukemia in mice was studied. inoculation of mice with trichinella spiralis larvae 15, 16 and 30 days before infection with rausher leukemia virus was shown to stimulate splenomegaly, whereas preinoculation of rausher leukemia virus at 6, 12 and 18 days before infection with trichinella spiralis resulted in inhibition of splenomegaly. under the experimental conditions used, no effect of t. spiralis on reproduction of rausher leukemia ... | 1975 | 1162955 |
| the development of alkaline phosphatase in trichinous muscle. | the development of alkaline phosphatase during invasion and encystment of trichinella spiralis in rat skeletal muscle fibres was studied at the ultrastructural level. on day 14 after infection, the enzymatic activity is found in proliferating parts of the t-tubular system and in parts of the plasmalemma. in cells, in which a strong hyperplasia of this system is noted. alpase is present in the abundant network of stratified and concentric membranes from which a large number of pinocytic vesicles ... | 1975 | 1150485 |
| the participation of c'3 and mg++ in the mediation of cell adherence reactions (car) to trichinella spiralis in normal non-immune sera. | 1975 | 1139357 | |
| trichinella spiralis: morphological characteristics of male and female intestine-infecting larvae. | 1975 | 1126422 | |
| selective immunodepression in mice by trichinella spiralis extracts and infections. | 1975 | 1125990 | |
| trichinella spiralis: phospholipase in sensitized mice after challenge. | 1975 | 1123017 | |
| adaptive changes in muscle fibers infected with trichinella spiralis. | ultrastructural changes which occurred in infected skeletal muscle fibers after infection with larvae of trichinella spiralis were followed on a daily basis utilizing synchronous infections. no changes were observed in muscle fiber architecture during the first 2 days of intracellular infection. however, on day 3, a space containing various sarcoplasmic elements developed between the plasma membrane and myofilaments. widening near the regions of triads was also observed at this time. on day 4 th ... | 1975 | 1119537 |
| trichinella spiralis: growth of the intracellular (muscle) larva. | 1975 | 1116513 | |
| [rapid detection of trichinella spiralis infection in its focus]. | 1975 | 1111237 | |
| application of immunofluorescence and immunoenzyme methods in the serodiagnosis of trichinella spiralis infection. | to detect antibodies to t. spiralis in sera, the if methods with the cuticle of t. spiralis larvae (the tube test) was compared to the cryostat method. in the latter method, cryostat sections were prepared from isolated t. spiralis larvae or from tongue or diaphragm musculature in which encysted t. spiralis larvae were present. in this case, both cuticle and internal structures were employed as antigenic sites. the cryostat method proved to be more sensitive than the tube test. with the cryostat ... | 1975 | 1101773 |
| [immunofluorescence technique in diagnosis of trichinellosis in swine. ii. comparative investigations with the tube test and the cryostate method (author's transl)]. | a series of comparative if tests have been made on serum samples from 9 spf pigs experimentally infected with trichinella spiralis (50-500 larvae per animal). the techniques applied included a tube test (antigen: whole trichinella larvae), and a cryostat test (antigen: sections of trichinella larvae). with the cryostat test a positive reaction was recorded in 2 animals already on the 6th day and in 5 animals on the 13th day p.i., while with the tube test such reaction was not demonstrated until ... | 1975 | 1096076 |
| [immunofluorescence technique in diagnosis of trichinellosis in swine. i. investigations with the tube test (author's transl)]. | experiments have been made with serological demonstration of trichinella spiralis infections in swine. the technique applied was the indirect immunofluorescence tube test with whole larvae of t. spiralis as antigen. the blood samples tested were taken from groups of spf swine inoculated with, respectively, 50, 150, 500 and 1500 trichinella larvae. in animals inoculated with at least 150 larvae, antibodies could be demonstrated 3-5 weeks p.i. until the investigation was finished 6-7 months later. ... | 1975 | 1096075 |
| evaluation of soluble-antigen fluorescent antibody test for antibodies to trichinella spiralis in experimentallly infected swine. | the soluble-antigen fluorescent antibody (safa) test was evaluated at intervals from 7 days to 1 year in 42 swine infected with 25, 100, 500, 2,500, 12,000, or 250,000 trichinella spiralis larvae. serums were test positive as early as 14 days after exposure in swine fed 25 larvae and as early as 7 days in swine fed 100 or 500 larvae. serums of all swine fed larger numbers of larvae were test positive by day 17 and remained test positive for the duration of the experiment. fluorescence obtained i ... | 1975 | 1094864 |
| leucoagglutination and cytotoxicity of the serum of infected mice and of extracts of trichinella spiralis larvae and the capacity of infected mouse sera to prolong skin allografts. | the sera of mice infected with the nematode trichinella spiralis agglutinate and kill homologous lymphoid cells in vitro. the agglutinating activity is present in the sera of infected animals on the 7th day following inoculation with the parasite, rises to a maximum on the 30th day of the infection and then decreases. the leucoagglutinating titre of these sera is related neither to the level of the inoculating dose of parasites nor to the intensity of muscle infection. the agglutinating and leuc ... | 1975 | 1093968 |
| antigenicity of the newborn larvae of trichinella spiralis. | 1975 | 1092832 | |
| absence of intestinal mast cell response in congenitally athymic mice during trichinella spiralis infection. | 1976 | 1087373 | |
| t-dependent suppression of the primary antibody response to sheep erythrocytes in mice infected with trichinella spiralis. | 1976 | 1086721 | |
| cellular immunity in peyer's patches of rats infected with trichinella spiralis. | a rat model of trichinella spiralis gut infection was used to observe the sequence of developing cellular immunity in peyer's patches and other lymphoid tissues. whereas cellular reactivity (lymphocyte blastogenesis) for worm antigens was evident in mesenteric lymph nodes draining the gastrointestinal tract within 3 days after infection, peyer's patch lymphocytes developed maximal reactivity 2 to 3 weeks later at the same time as the spleen and other lymphoid tissues. furthermore, the immune rea ... | 1976 | 1082443 |
| transfer of delayed-type hypersensitivity by cells (spleen, mesenteric lymph node) in trichinella spiralis infection in mice. | 1975 | 1081309 | |
| immune response to trichinella spiralis in the rat. i. development of cellular and humoral responses during chronic infection. | the immune response of rats to infection with trichinella spiralis was studied serially for more than 1 year. initial antigen-specific cellular reactivity, assessed by the lymphocyte transformation response, developed in the draining mesenteric nodes 3 days after infection. after 1 week reactive lymphocytes were detectable in the spleen and circulating blood, but the more 'remote' peripheral nodes did not harbor antigen-reactive cells until late in the second week. thereafter, the patterns of an ... | 1975 | 1080134 |
| a sausage-associated outbreak of trichinosis in illinois. | twenty-three of 50 members of an extended dutch-german family and their close friends who ate raw homemade summer sausage became ill with trichinosis; 12 patients were hospitalized for an average of 10 days each. the sausage had been made in three different batches according to an old family recipe. one of the batches made from usda-inspected pork was found to contain trichinella spiralis larvae by two illinois state laboratories. the other two batches were negative. seventeen of the 23 patients ... | 1976 | 1034441 |
| [biochemical changes in the white rat with trichinella spiralis parasitosis. experimental study]. | 1976 | 1027085 | |
| [feeding behavior of trichinella as a leading factor of adaptation to the body of the mammals]. | studies were carried out of the permeability of the cuticle of trichinella spiralis (owen, 1835) for fluorochromes and histidine, the filling of the mid-gut and the amino-acids contents in it. the quantity of glicogene in different organs was estimated. a conclusion has been grown that a larva consumes food through the integuments of its body; intestinal trichinella use within the first 20 hours of their development the reserves of glicogene and later consume food monomeres and oxygen from the h ... | 1976 | 1023143 |
| suppression of giardiasis during the intestinal phase of trichinosis in the mouse. | the interaction of the intestinal phases of giardia muris and trichinella spiralis was investigated in swiss albino mice. intraoesophageal inoculation of g. muris cysts seven days before, or seven days after, similar inoculation of t. spiralis larvae resulted in significant reduction in the numbers of giardia trophozoites in small bowel and giardia cysts in stools. this effect was not observed when g. muris cysts were administered after resolution of the intestinal phase of trichinosis. giardias ... | 1976 | 1017715 |
| effect of trichinella spiralis (oven, 1835) infection on ultrastructure of epithelium of small intestines in germfree or conventional mice. | 1976 | 1016899 | |
| serum and antral gastrin levels in rats infected with intestinal parasites. | serum and antral gastrin were measured in rats infected with either trichinella spiralis or hymenolepis diminuta as a step in testing the hypothesis that parasites change certain aspects of host physiology by altering gastrointestinal (gi) hormone levels or responses to gi hormones. parasitism with t. spiralis was associated with inflammatory changes in the small bowel mucosa and with a significant increase in serum gastrin. neither changes in hormone level nor inflammation were induced in tapew ... | 1976 | 1008130 |
| [immune elimination of trichinella spiralis in rats. 2. transfer of sensitized cells]. | 1976 | 1007703 | |
| the effects of mebendazole and fenbendazole on trichinella spiralis in mice. | oral administration of either mebendazole or fenbendazole at 50 mg/kg body weight was effective in killing a 7-hr trichinella spiralis infection in mice. adult worms, 72 hr postingection, were unaffected by the same dose of fenbendazole, while mebendazole showed partial activity. both mebendazole and fenbendazole were active against developing muscle larvae. mebendazole was effective against encysted muscle larvae while 50 mg of fenbendazole per kg per day for 7 days from 28 days postinfection f ... | 1976 | 1003277 |
| response of ovine prolactin-treated mice to initial infection with trichinella spiralis. | the effects of ovine prolactin on the expulsion of adult trichinella spiralis were studied in adult virgin female mice. the results showed that ovine prolactin-treated mice had an altered pattern of worm expulsion; i.e., more adult worms were recovered from prolactin-treated mice than from normal control mice, 18 days after infection. | 1976 | 1003276 |
| habitat and reproductive behavior of trichinella spiralis. | the normal niche of trichinella spiralis adults was found to be in the epithelial layer of the mucosa of the small intestine of its host. most worms were found in the epithelium at the base of the villi and in the glandular crypts. copulation and insemination occurred between 30 and 32 hr postinfection, all although these acts were never observed, it was concluded that copulation and insemination took place in the epithelial layer of the mucosa. a majority of the adults were found to be complete ... | 1976 | 1003275 |
| effects on murine trichinosis of niridazole, a suppressant of cellular but not humoral immunological responses. | two groups of mice infected with trichinella spiralis were treated with niridazole (100 mg/kg), one on alternate days, the other daily. both regimens failed to influence the numbers of adult worms in the intestines or larvae in the muscles compared with untreated control mice. mice treated with niridazole daily, but not those treated on alternate days, showed a significant reduction in the inflammatory reaction to larvae in the muscles. immediate footpad swelling in response to injection of solu ... | 1976 | 999358 |
| [the immune elimination of trichinella spiralis in rats. 1. characterization of the elimination of worms]. | 1976 | 998060 | |
| the hematopoietic microenvironment of the bone marrow: an ultrastructural study of the stroma in rats. | the bone marrow contains branching vascular sinuses lying in a fibroblastic stroma which supports hematopoiesis. this paper describes the stroma and vascular sinuses by scanning and transmission electron microscopy and in freeze-fracture etch replicas in normal fat femoral marrow and in rats made eosinophilic by larvae of trichinella spiralis. the stroma consists primarily of reticular cells which ensheath sinuses as adventitial cells and branch into the surrounding hematopoietic space. they for ... | 1976 | 984472 |
| the stichosome and its secretion granules in the mature muscle larva of trichinella spiralis. | the stichosome of the mature muscle larva of trichinella spiralis consists of a single row of 45 to 55 stichocytes. each stichocyte is about 25 mum in diameter and possesses a single nucleus. a duct leads from each stichocyte to the lumen of the esophagus. the stichocyte cytoplasm contains mitochondria, structures resembling golgi-complexes, rough endoplasmic reticulum, and usually 1 of 2 types of secretory granules. the alpha-granule measures about 800 mn in diameter, contains a prominent inclu ... | 1976 | 978367 |
| accelerated expulsion of adult trichinella spiralis in mice given lymphoid cells and serum from infected donors. | immunity to the adult stage of trichinella spiralis, assessed by an acceleration of worm expulsion, was transferred to recipient mice with mesenteric lymph node cells (mlnc) or serum taken from infected donors. immunity was transferred most effectively by mlnc taken from donors infected for 8 days, i.e. donors actively responding to infection. transfer of both mlnc and serum brought about a marked acceleration of worm expulsion in all cases, even where mlnc or serum given separately failed to tr ... | 1976 | 967521 |
| altered small bowel propulsion associated with parasitism. | experiments were designed to test the hypothesis that alterations of intestinal motility accompany enteric helminth infections. motility was measured in rats during the intestinal phase of infection with the nematode trichinella spiralis by following the transit of radioactive chromium through the gut. intraduodenal catheters were surgically implanted in rats. one week after the operation one group of animals was infected with 8 x 10(3) t. spiralis larvae and a second group was infected with 16 ... | 1976 | 955350 |
| effect of lactation on cell-mediated immunity of swiss mice to trichinella spiralis. | 1976 | 949745 | |
| production of different classes of immunoglobulins in rats infested with trichinella spiralis. | 1976 | 939584 | |
| a re-evaluation of the slide flocculation test for the diagnosis of schistosomiasis with adult worms as antigen. | the present study was conducted to determine whether extracts from adult schistosoma mansoni could be coated onto cholesterol-lecithin crystals. of particular interest was the use of stunted schistosomes (ss) recovered from rabbits. the reactions obtained with this antigen in this slide flocculation (sf) test were compared with those employing antigens from cercariae and mature adult worms. the stunted schistosome sf test (sfss) showed a high sensitivity and specificity while cercarial antigen s ... | 1976 | 937633 |
| the prevalence of trichinella spiralis in foxes (vulpes vulpes) and other game species in denmark. | a survey of the rate of infection with trichinella spiralis among game animals in denmark is given with special regard to foxes. a total of 5084 foxes and 293 mustelidae were examined, most of them by a combined digestion and baermann technique. deep-frozen samples were examined by a method including digestion, filtration, and sedimentation. four foxes were found infected (cf. fig. 1). three of them were shot inside or just outside a fenced area within which wild boars had previously been found ... | 1976 | 934811 |
| an investigation of north atlantic whales for trichinosis. | in 1971, 81 finback (balaenoptera physalus), 119 sei (b. borealis), two piked (b. acutorostrata), 15 humpback (megaptera novaeangliae) and one sperm whale (physeter catodon) taken in the north atlantic off the newfoundland and nova scotia coasts were examined for the presence of trichinella spiralis. all 218 whales were negative for trichinosis. | 1976 | 933319 |
| increased resistance in the rat to strongyloides ratti following immunization against trichinella spiralis. | 1976 | 932925 | |
| trichinella spiralis infection in congenitally athymic (nude) mice. parasitological, serological and haematological studies with observations on intestinal pathology. | in six experiments the course of a trichinella spiralis infection in congenitally athymic (nu/nu) mice and their heterozygous thymus-bearing littermates (+/nu) was followed. in the +/nu mice worms were expelled at day 10 post infection. in nu/nu mice worms remained in the intestine until the end of the observation period (83 days post infection). in testing the yield of muscle larvae in +/nu and nu/nu mice 4--5 times more muscle larvae were isolated from nu/nu mice than from infected +/nu mice. ... | 1977 | 924522 |
| kinetics of immunological responses, resistance to reinfection, and pathological reactions to infection with trichinella spiralis. | changes in immune responses, resistance to reinfection, and pathological reactions were studied serially in mice that had been infected for four to 40 weeks with 150 larvae of trichinella spiralis. immediate footpad hypersensitivity reactions to antigens of trichinella were present throughout the period of observation. delayed hypersensitivity reactions 48 hr after injection of antigen were first seen in mice infected for 14 weeks and gradually increased in size thereafter. intestinal adult worm ... | 1977 | 908853 |
| reactivity and specificity of trichinella spiralis fractions in cutaneous and serological tests. | six diethylaminoethyl-cellulose fractions of a larval trichinella spiralis extract, an ascaris suum extract, and a nonrelated protein were used for cutaneous tests in guinea pigs with 8-, 14-, and 73-day-old t. spiralis infections, in guinea pigs with 13-day-old a. suum infections, and in normal guinea pigs. a selected t. spiralis fraction was used in hemagglutination (ha) tests with sera of 8 t. spiralis-infected rabbits, 41 sera of trichinellosis patients positive by bentonite agglutination te ... | 1977 | 908745 |
| immunity to trichinella spiralis. vii. resistance stimulated by the parenteral stages of the infection. | in three experiments mice were given three intravenous injections of trichinella spiralis newborn larvae produced in vitro. following a challenge infection of newborn larvae the mice were shown to be on the average 85% resistant i.e., only 15% of the challenge larvae developed to encysted muscle stage larvae in these mice; when the challenge consisted of normal muscle larvae administered per os, the mice were 51% resistant. neither the number nor longevity of adult worms in the intestines was af ... | 1977 | 886409 |
| trichinella spiralis: taxes of first-stage migratory larvae. | 1977 | 885215 | |
| dynamics of circulating antibodies against trichinella spiralis after application of anthelmintics. | formation and dynamics of circulating antibodies were studied in mice experimentally inefected with t. spiralis and treated with mebendazole. latex-fixation tube was used in the experiment. in the control group of untreated mice the antibodies were detected on the 21st day after infection. the antibody level reached the maximum on day 76 and low titres were found still on day 207 after infection. in mice treated with mebendazole in the intestinal phase of trichinellosis, the antibodies were dete ... | 1977 | 881141 |
| evidence for the involvement of a bone marrow-derived cell population in the immune expulsion of trichinella spiralis. | when mice were irradiated immediately before infection with trichinella spiralis there was a profound and long-lasting interference with their ability to expel adult worms from the intestine. irradiation given after the fifth day of infection was progressively less effective in this respect. the ability to expel worms was not restored when mesenteric lymph node cells (mlnc) were transferred (a) on the day of infection in mice irradiated one day previously, or (b) on day 7 of an infection in mice ... | 1977 | 876679 |
| transfer of immunity to trichinella spiralis in the mouse with mesenteric lymph node cells: time of appearance of effective cells in donors and expression of immunity in recipients. | cells capable of transferring immunity to trichinella spiralis, i.e. of accelerating adult worm expulsion, were present in the mesenteric lymph nodes of mice infected for 4, 6 or 8 days, but not in mice infected for only 2 days. the time-course of worm expulsion in mice infected on the day of transfer was similar in recipients of day 4 or day 8 cells, expulsion becoming marked only when the recipients had been infected for at least 6 days. transfer of cells 4 or 6 days after infection did not re ... | 1977 | 876678 |