Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
|---|
| isolation of a cured strain from corynebacterium diphtheriae pw8. | a nonlysogenic, non-toxinogenic strain was isolated from the pw8 strain of c. diphtheriae by two-step ultraviolet induction. this strain was lysed by phages derived from the pw8 strain but not by beta phages from the c7(beta) strain. when this cured strain was lysogenized with phages from the pw8 strain, toxin production by the resulting lysogens was about a half or a quarter of that of the parent strain pw8. | 1979 | 115787 |
| activity of penicillin, erythromycin, and cephalosporins against isolates of corynebacterium diphtheriae from cutaneous lesions. | 1979 | 114513 | |
| [appearance in domestic animals of corynebacterium diphtheriae and other corynebacterium strains pathogenic for man]. | 1979 | 113847 | |
| [interrelationship of toxin formation with proteolytic enzyme synthesis in the process of cultivating diptheria microorganisms]. | for the first time the synthesis of proteolytic enzymes by corynebacterium diphtheriae has been shown to precede the process of toxin formation. the process of controlling the proteolytic activity of enzymes seems to be a suitable basis for the evaluation of toxin formation in mathematically planned experiments with strictly controlled tasks. | 1979 | 112807 |
| [a tropical ulcus cruris caused by corynebacterium diphtheriae?]. | 1979 | 112483 | |
| occurrence of 3-oxo-acyl groups in the 6,6'-diesters of alpha-d-trehalose. new glycolipids related to cord factor from corynebacterium diphtheriae. | 1979 | 111936 | |
| [heteromorphism of the corynebacteria. iii. d- (dark) and c- (clear) cell types and multiseptate specimens]. | a population of corynebacterium diphtheriae may consist of cells with accented (osmiophilic) cytoplasm (cells of the "dark" type, or d type) and cells with cytoplasm having no pronounced osmiophilic properties (cells of the "clear" type, or c type). the divergence of the population into cells of the d and c types occurs at the stage of cell division, the original mother cell being able to divide into 2 or more individual cells belonging to different types (elongated multiseptate cells). at the s ... | 1979 | 111440 |
| [antibacterial immunity in diphtheria. experimental research]. | a number of 700 guinea pigs were immunized by parenteral route with non-toxigenic corynebacterium diphtheriae strains, then inoculated with various doses of homologous and heterologous toxigenic c. diphitheriae strains. the results showed that non-toxigenic c. diphtheriae strains confer a certain degree of protection when the challenge is done with homologous toxigenous strains, especially when not more than 500 million germs/ml are used for the challenge dose. this suggests that the carriage of ... | 1979 | 111333 |
| epidemiologic studies among amerindian populations of amazônia. i. pyoderma: prevalence and associated pathogens. | pyoderma was studied among a representative sample of the residents of four remote amerindian villages, amazonas state, brazil, during july-august 1976. the overall prevalence among the 775 inhabitants examined was 11%, with little intervillage variation. when the attack rates for the entire sample population were calculated by 5-year age intervals, the 0- to 4-year-olds had the highest rate, 31%. the highest prevalence, 38%, was found among 3-year-olds. attack rates were not apparently related ... | 1979 | 110164 |
| a modified gel-diffusion technique for testing toxigenicity of corynebacterium diphtheriae. | 1978 | 108219 | |
| bactericidal effects of anesthetics. | 1979 | 107831 | |
| ige synthesis in man. ii. comparison of tetanus and diphtheria ige antibody in allergic and nonallergic children. | 1979 | 107210 | |
| structural determination of 'cord factor' from a corynebacterium diphtheriae strain by a combination of mass spectral ionization methods: field desorption cesium cationization and electron impact mass spectrometry studies. | the composition and structure of a preparation of 'cord factor' (di-beta-hydroxy acyl trehaloses) from corynebacterium diphtheriae have been determined by a combination mass spectral ionization methods. the methods were tested by means of synthetic 6,6'-dicorynomycolate of alpha-d-trehalose prior to their use on natural products. the determination of the molecular weight of the components and the estimation of their relative abundance in the natural mixture were made by field desorption mass spe ... | 1978 | 106902 |
| [heteromorphism of corynebacteria. i. macrocells]. | a possibility of formation of macrocells (mac) of diphtheria bacilli was expressed to a different degree; the extreme expression are giant and supergiant forms. giant forms with section dimension of 3--5micron retained their capacity to disorderly septation with the resultant formation of microcells (mic). apparently some of the septa were not realized. supergiant forms were revealed as a layer and its transverse section. the length of the latter reached 30micron with the transverse section of 2 ... | 1978 | 106605 |
| [testing of a system of unidirectional serologic reactions for detection of diphtheria antigens and antibodies]. | 1979 | 106599 | |
| three variants of corynebacterium diphtheriae subsp. mitis (belfanti) isolated from a throat specimen. | three variants of a corynebacterium diphtheriae subsp. mitis strain belfanti, two toxigenic (phage types 7 and 11) and one nontoxigenic (phage type 7), were simultaneously isolated from the throat of an adult. | 1978 | 106070 |
| [use of microbial cells of corynebacterium diphtheriae for preparing a nutrient medium]. | nutrient media prepared on the basis of microbial cells (corynebacteria diphtheriae) proved to be no less nutrient in comparison with conventional media prepared on the full-value food products. use of diphtheria bacilli (by-products of diphtheria toxoid production) as the basis for nutrient media permitted to use up to 30% less food products for this purpose. | 1979 | 105520 |
| [a leg ulcer from the tropics caused by corynebacterium diphtheriae?]. | 1979 | 104183 | |
| [participation of bacterial neuraminidases in the development of disease]. | 1978 | 103344 | |
| quantitative studies on competitive activities of skin bacteria growing on solid media. | earlier quantitative investigations of antagonism between skin bacteria were based on the use of liquid cultures, but a more realistic model has now been devised, based on the use of the surfaces of solid media. pure or mixed inocula were spread evenly over suitable agar media in petri dishes marked out with a standard grid. growth curves were constructed from viable counts of the surface bacteria after they had been removed from excised squares of the agar media and dispersed. the method was hi ... | 1978 | 102799 |
| isolation, structural studies and chemical synthesis of a 'palmitone lipid' from corynebacterium diphtheriae. | the isolation of a 'palmitone lipid' from corynebacterium diphtheriae is described. the use of a temporary hydrophobic protecting group allows the obtaining of the lipid in free and pure form. structural studies by chemical degradation and mass spectrometry allow one to propose structure ic for this compound, namely 6-(2-tetradecyl 3-keto octadecanoyl)-alpha-d-trehalose. this structure was confirmed by chemical synthesis. | 1978 | 102431 |
| [comparative study of the bactericidal action of the body of ornithodoros papillipes ticks]. | experiments in vivo have shown that the ticks of ornithodoros papillipes inhibit both gram-positive and gram-negative bacteria. on gram-positive microorganisms most sensitive to bactericidal effect of ticks have turned to be micrococci, staphylococci, streptococci and bacteria of diphtheria, of gram-negative ones--bacillus coli. of gram-positive microorganisms less sensitive were listeria, of gram-negative ones--salmonellae, agents of tularemia and pseudotuberculosis. at the infection with bacte ... | 1978 | 100756 |
| control of corynebacteriophage reproduction by heteroimmune repression. | corynebacteriophages beta and gamma are closely related but heteroimmune; hence, gamma reproduces in c7(beta). a series of gamma mutants, designated gamma-bin (beta-inhibited), has been isolated. they reproduce in only 2 to 14% of infected c7(beta) cells, and, as a result, plaque with an efficiency of 10(-4) to 10(-5) on this strain. the proportion of c7(beta) cells in which gamma-bin phage can replicate is increased to 30 to 80% when immunity is lifted by uv induction of c7(beta) or by heat ind ... | 1978 | 100610 |
| [epiedmiologic significance of the distribution of corynephages in different collectives]. | corynephage distribution was studied in the nasopharyngeal washings of 252 persons infected with c. diphtheriae of gravis type, toxigenic (21 patients and 147 carriers) and non-toxigenic ones (84 carriers), and in 468 uninfected persons in collective bodies under different epidemic conditions. corynephages were isolated from the nasopharyngeal washings only in persons infected with toxigenic c. diphtheriae--in 4 (of 21) patients, and in 21% (of 147) carriers. phages tox+ (4--6.2%) were revealed ... | 1978 | 99930 |
| [serologic relationship between toxigenic and nontoxigenic c. diphtheriae with reference to the cultural variant gravis]. | 1978 | 99927 | |
| vaccination and hodgkin's disease. | 1978 | 99187 | |
| evidence that the regulation of diphtheria toxin production is directed at the level of transcription. | it has been known for several decades that iron inhibits the production of diphtheria toxin by corynebacterium diphtheriae by preventing expression at maximal levels. we examined the inhibition kinetics of toxin production after the addition of either iron or rifampin to iron-limited cultures of c7 (betatox+). iron-mediated inhibition of toxin production was found to be linear within the range of 16 nm to 16 micron. the inhibition kinetics following the addition of iron or rifampin was almost id ... | 1978 | 98519 |
| [prospects for the use of blood substitutes made in the ussr with the expired date of validity]. | as revealed, blood substitutes--aminopeptide, caseine hydrolysate, and hydrolysine with the expired date of validity could be used as the basis of nutrient media for the cultivation of bacteria. bacterial growth proved to be the optimum in addition to the blood substitutes of a 0.25--0.5% of yeast extract. | 1978 | 97885 |
| role of exotoxins in bacterial pathogenicity. | 1978 | 97256 | |
| isolation of the l-phase variant from toxigenic corynebacterium diphtheriae c7(beta). | the l-phase variant was isolated from lysogenic strain c7(beta) of corynebacterium diphtheriae by the penicillin disk tecnnique on an agar medium containing 3.7% brain heart infusion, 3% nacl, 1.25% grycine, 1% noble agar, and 10% horse serum. the l-phase formed a "fried egg" colony; it was resistant to antibiotics that inhibit biosynthesis of bacterial cell walls but was susceptible to antibiotics that act on the protein-synthesizing system. after several transfers of the l-phase initially isol ... | 1978 | 97222 |
| rapid determination of corynebacterium diphtheriae toxigenicity by counterimmunoelectrophoresis. | a method for detecting toxin production in corynebacterium diphtheriae cultures by counterimmunoelectrophoresis is described. precipitin lines were observed in toxigenic strains in 30 min. | 1978 | 96129 |
| value of acid metabolic products in identification of certain corynebacteria. | acid metabolic products of 23 strains of human and animal pathogenic corynebacteria, representing eight different species, were determined by gas chromatography. the results showed that the species examined were metabolically heterogeneous and could be presumptively identified based on the acid products produced. corynebacterium equi did not produce any acids; c. renale produced lactate; and c. pyogenes produced major amounts of lactate, variable amounts of acetate, and minor amounts of succinat ... | 1978 | 96126 |
| polypeptide antibiotic 26a from bacillus subtilis. iv. evaluation of biological in vivo activity. | the studies performed with the antibiotic 26a, which has a close resemblance to bacitracin family polypeptide antibiotics, revealed a prominent therapeutic and protective actions. the antibiotic is characterized by a moderately low toxicity, lack of cytotoxic and cytostatic effects on several tissue cultures, and therapeutic effectiveness in lethal streptococcal infections in mice, and corynebacterial infections in guinea pigs. | 1978 | 86285 |
| [bacteriocinogenic activity of corynebacterium diphtheriae]. | 1978 | 81920 | |
| an unusual case of cutaneous diphtheria. | 1978 | 79663 | |
| [adsorption of the antigen-reactive cells on the membrane reinforced immunosorbent]. | 1977 | 72857 | |
| response of cultured mammalian cells to the exotoxins of pseudomonas aeruginosa and corynebacterium diphtheriae: differential cytotoxicity. | the sensitivities of 21 mammalian cell lines to the exotoxins of pseudomonas aeruginosa and corynebacterium diphtheriae were measured. each line exhibited 1-4 log differences in sensitivities to the two toxins. no species-specific sensitivities were noted for pseudomonas exotoxin while diphtheria exotoxin was most potent in cells of monkey origin, followed by human and hamster cells. rat- and mouse-derived cell lines were very insensitive to diphtheria exotoxin. the rates of cellular intoxicatio ... | 1977 | 65205 |
| [minor diphtheria epidemic in a cologne children's home (author's transl)]. | between may and july 1972, 12 children aged from 7 to 14 were admitted to the cologne university children's hospital suspected of having diphtheria. in 10 cases the tonsils or pharyngeal cavity were affected. one case of wound diphtheria and one of nasal diphtheria were observed. the clinical suspicion was confirmed in 8 of 12 cases by detection of the pathogen coryne-bacterium diphtheroides mitis. 11 patients were discharged from the hospital after being treated for between 2 to 6 weeks, but 5 ... | 1976 | 64924 |
| [use of fermented and purified diphtheria antitoxin for determination of pathogenicity of corynebacterium diphtheriae]. | 1976 | 61328 | |
| quantitative assay of diphtherial toxin and of immunologically cross-reacting proteins by reversed passive hemagglutination. | a reversed passive hemagglutination (rpha) assay for diptherial toxin has been developed. antitoxic antibodies were isolated from commercially available equine diptherial antitoxin by immunoabsorption using highly purified diphtherial toxin covalently linked to sepharose 4b. formalinized, tanned sheep erythrocytes sensitized with the purified antitoxic antibodies are specifically agglutinated by diphtherial toxin but are not agglutinated by extracellular antigens of corynebacterium diptheriae th ... | 1975 | 54339 |
| [bacteriological studies of butirosin sulfate, a new aminoglycoside antibiotic (author's transl)]. | 1975 | 51941 | |
| letter: recognition of diphtheria. | 1975 | 48850 | |
| non-toxigenic corynebacterium diphtheriae in a boarding school. | a non-toxigenic strain of corynebacterium diphtheriae var. gravis was isolated from 31 boys during an outbreak of sore throats at a boarding school of 15 staff and 134 pupils. despite the non-toxigenicity of the strain involved, conventional isolation procedures were observed and all boys at the school were treated with antibiotics. restrictions on the school were only relaxed when no further carriers were detected. the rationale of such management of an episode involving a non-toxigenic strain ... | 1975 | 48687 |
| letter: recognition of diphtheria. | 1975 | 47573 | |
| letter: avirulent corynebacteria. | 1975 | 47127 | |
| letter: recognition of diphtheria. | 1975 | 46974 | |
| diphtheria toxin. | 1977 | 20040 | |
| the detection of toxin production by corynebacterium diphtheriae in diagnostic laboratories. | in vitro tests for assessing the toxigenicity of strains of c. diphtheriae using the original agar plate precipitin method of elek are unreliable. at high concentrations of antitoxin (500-1000 u/ml) multiple non-specific precipitin lines occur making interpretation difficult. increased specificity was obtained by diluting the antitoxin but this in turn caused a delay in the appearance of toxin-antitoxin lines. also, the failure of lines to appear on media enriched with unsuitable serum may lead ... | 1976 | 9614 |
| significance of microorganisms found in throat swabs (author's transl). | 1976 | 3776 |