Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
|---|
| haematophagous bats in brazil, their role in rabies transmission, impact on public health, livestock industry and alternatives to an indiscriminate reduction of bat population. | haematophagous bats exist only in latin america, from méxico to the northern provinces of argentina. they are represented by three species, desmodus rotundus, diphylla ecaudata and diaemus youngii. while two species feed only on blood of wild birds, one species, d. rotundus, causes losses feeding on livestock and could be a vector for rabies virus. the cases in which humans were bitten by the bat have increased in brazil. bats became a target of control activities by farming communities and loca ... | 2003 | 14720182 |
| evaluation of a taqman pcr assay to detect rabies virus rna: influence of sequence variation and application to quantification of viral loads. | published assays that use taqman pcr are consistently sensitive, rapid, and readily transferable. here we describe a taqman pcr-based method for the detection of rabies virus (rv) rna in tissue samples. we show that the method has an acceptable linear range, is both sensitive and specific, and, importantly, correlates with the concentration of infectious virus. in addition, the levels of rv-specific amplification are adjustable according to the levels of an endogenous control (beta-actin mrna), ... | 2004 | 14715769 |
| [recombinant replication-defective adenovirus based rabies vaccine]. | to construct and characterize recombinant adenoviruses containing glycoprotein (gp) gene from rabies virus cvs-n2c strain. | 2003 | 14714304 |
| effect of age on immune parameters and the immune response of dogs to vaccines: a cross-sectional study. | the evaluation of anti-aging intervention strategies in dogs would benefit from reliable quantitative biomarkers of aging. in the present study, the expression of various immune parameters was measured in young and old dogs to identify potential biomarkers of aging. the second goal of the study was to determine the effect of age on the immune response to vaccines. the immune function, including the antibody response to vaccines, was determined in 32 young adult (3.15+/-0.8 years of age) and 33 o ... | 2004 | 14700539 |
| prevalence of rabies virus and hantaan virus infections in commensal rodents and shrews trapped in bangkok. | five hundred rodents and shrews (rattus norvegicus: 458, rattus rattus: 28, rattus exulans: 5, mus musculus: 4 and suncus murine: 5) trapped from the fresh food markets around bangkok area were investigated for rabies virus and hantaan virus infections. no rabies viral antigens in the animals' brains were detected by direct immunofluorescence. on the other hand, antibodies to hantaan virus were demonstrated in the sera of 7 (1.53%) r. norvegicus caught in various markets using a particle aggluti ... | 2003 | 14696782 |
| characterization of a slow-migrating component of the rabies virus matrix protein strongly associated with the viral glycoprotein. | we investigated multiple forms of rabies virus matrix (m) protein. under non-reducing electrophoretic conditions, we detected, in addition to major bands of monomer forms (23- and 24-kda) of m protein, an m antigen-positive slow-migrating minor band (about 54 kda) in both the virion and infected cells. relative contents of the 54-kda and monomer components in the virion were about 20-30% and 70-80% of the whole m protein, respectively, while the content of the 54-kda component was smaller (about ... | 2003 | 14695448 |
| in vitro inactivation of the rabies virus by ascorbic acid. | the current recommended inactivating agent for the rabies virus, beta propiolactone (bpl) is very expensive and potentially carcinogenic. there is a need to evaluate alternative chemicals, which will inactivate the virus without affecting its antigenicity. in this study the effect of ascorbic acid on the infectivity of the rabies virus has been investigated. | 2004 | 14690777 |
| rabies surveillance in the united states during 2002. | during 2002, 49 states and puerto rico reported 7,967 cases of rabies in nonhuman animals and 3 cases in human beings to the centers for disease control and prevention, an increase of 7.2% from the 7,436 cases in non-human animals and 1 case in a human being reported in 2001. more than 92% (7,375 cases) were in wild animals, whereas 7.4% (592) were in domestic species (compared with 93.3% in wild animals and 6.7% in domestic species in 2001). compared with cases reported in 2001, the numbers of ... | 2003 | 14690203 |
| unusual manifestation of hepatic encephalopathy in two irish wolfhound siblings. | in hepatic encephalopathy the brain lesions are usually characterised by polymicrocavitation, preferentially in the white matter, and the occurrence of alzheimer type ii cells. this paper describes an unusual manifestation of hepatic encephalopathy in two irish wolfhound siblings in which the white matter was not involved predominantly. both puppies had developed progressive neurological disturbances and signs of blindness. histologically, there were widespread spongiform changes in the neuropil ... | 2003 | 14682542 |
| macro-architecture of basal ganglia loops with the cerebral cortex: use of rabies virus to reveal multisynaptic circuits. | we have used retrograde transneuronal transport of rabies virus to examine basal ganglia connections with the cerebral cortex. we injected rabies into the primary motor cortex (m1) or into area 46 of cebus monkeys. a 4-day survival time was long enough to allow transport of rabies from the injection site to 'third-order' neurons in the basal ganglia. after either m1 or area 46 injections, third-order neurons were found in the external segment of the globus pallidus (gpe), striatum and subthalami ... | 2004 | 14653187 |
| combined use of radioimagers and radioactive 3'oh dna nick end labelling to quantify apoptosis in cell lines and tissue sections: applications to virus-induced apoptosis. | dna fragmentation is a key feature of the degradation phase of apoptosis. in this work we have developed an assay, based on radioimager (beta-imager and micro-imager) quantification of radioactive nick end labelling (ranel), which is quantitative, rapid and sensitive to study in vitro and in vivo induced apoptosis. to establish the technique, in vitro apoptosis of t cell lines was induced by stimulation of the fas receptor; cells were labelled using tdt-mediated [alpha-33p] dctp nick end labelli ... | 1999 | 14634279 |
| antibody response to purified chick embryo cell vaccine in equines for production of equine rabies immune globulin. | rabies is endemic in india. the post exposure treatment of class three bite cases, as recommended by the world health organization, must involve the use of rabies immunoglobulin as soon as possible and up to the seventh day of start of anti rabies vaccination. the annual requirement in india as projected by the ministry of health, government of india is about 1500 liters of purified anti rabies serum (erig). central research institute (cri), kasauli, being the sole producer of erig in india, an ... | 2003 | 14624792 |
| comparative evaluation of immunogenicity, reactogenecity and safety of purified chick embryo cell rabies vaccine and neural tissue rabies vaccine. | 1. to compare the protective antibody titres on day 14, 30 and 90 after giving intramuscular (im) injections of pcecv and subcutaneous injections of nervous tissue vaccine. 2. to compare the immunogenicity and safety of pcecv and ntv. | 2003 | 14621031 |
| efficacy of rabies immunoglobulins in an experimental post-exposure prophylaxis rodent model. | in a recently published syrian hamster animal challenge study [vaccine 19 (2001) 2273], a highly purified, heat-treated equine rabies immunoglobulin (perig ht, favirab) did not elicit satisfactory protection. the efficacies of this batch, a second stage perig ht batch and reference rig preparations (imorab, imogam rage pasteurised, berna antiserum) were compared in mice challenged with either ariana canine field strain or cvs strain. survival rates against ariana challenge with the second perig ... | 2003 | 14615152 |
| post-exposure therapy in mice against experimental rabies: a single injection of dna vaccine is as effective as five injections of cell culture-derived vaccine. | two rabies post-exposure therapies were comparatively evaluated: balb/c mice were challenged at day 0 with rabies virus and then received either a single dose of rabies dna vaccine administered at day 0, or five doses of cell culture-derived rabies vaccine administered at days 0, 3, 7, 15 and 28. both regimens, rapidly triggered protective levels of neutralizing antibodies against rabies virus in vaccinated mice. in addition, one injection of dna vaccine protected 53% of the challenged mice, com ... | 2003 | 14615144 |
| first human death associated with raccoon rabies--virginia, 2003. | rabies is an acute, progressive, incurable viral encephalitis, caused by the bite of an infected animal. in march 2003, a previously healthy man aged 25 years from northern virginia died from a diagnosed illness of meningoencephalitis of unknown etiology after a 3-week illness. histopathologic review of central nervous system tissues at cdc revealed viral inclusions suggestive of negri bodies, and subsequent tests confirmed a diagnosis of rabies. genetic sequencing identified a rabies virus vari ... | 2003 | 14614408 |
| covalently linked human immunodeficiency virus type 1 gp120/gp41 is stably anchored in rhabdovirus particles and exposes critical neutralizing epitopes. | rabies virus (rv) vaccine strain-based vectors show significant promise as potential live-attenuated vaccines against human immunodeficiency virus type 1 (hiv-1). here we describe a new rv construct that will also likely have applications as a live-attenuated or killed-particle immunogen. we have created a rv containing a chimeric hiv-1 env protein, which contains introduced cysteine residues that give rise to an intermolecular disulfide bridge between gp120 and the ectodomain of gp41. this cova ... | 2003 | 14610200 |
| chemokines and trance as genetic adjuvants for a dna vaccine to rabies virus. | an adaptive immune response is initiated by mature dendritic cells presenting processed antigen to nai;ve t cells. assuming that the magnitude of the immune response is influenced by the number and type of antigen-presenting dendritic cells and by the duration of antigen presentation, we tested if chemokines that bind to receptors expressed on immature dendritic cells or trance, a survival factor for mature dendritic cells, can serve as adjuvants. none of the immunomodulaters given as genetic ad ... | 2003 | 14609576 |
| further characterization of a cd99-related 21-kda transmembrane protein (vap21) expressed in syrian hamster cells and its possible involvement in vesicular stomatitis virus production. | the vap21, a cd99-related 21-kda transmembrane protein, was first detected in the enveloped virions that were grown in a syrian hamster-derived cell line, bhk-21 (sagara et al., 1997; yamamoto et al., 1999). we further tried to elucidate the nature and properties of vap21. the vap21 was detected in various organs of the syrian hamster as well as in the syrian hamster-derived cell lines (bhk-21 and hmlu-1). we could not detect the vap21 antigen in other cell lines derived from other animal specie ... | 2003 | 14605441 |
| characterization of rabies virus isolates in bolivia. | in latin america, rabies is still an important public health problem. canine rabies, and wild animal rabies, especially transmitted by hematofagous and insectivorous bats, has become an emerging problem in the countries of this region. we received 363 samples with a laboratory-confirmed rabies diagnosis from bolivia during l997-2001. from these, we could obtain 222 rabies virus isolates by intra-cerebral inoculation in mice. by antigenic characterization we could identify 147 isolates as variant ... | 2003 | 14602205 |
| isothermal amplification of rabies virus gene. | a sensitive and specific in situ amplification technique is needed to elucidate the dynamics of rabies virus in the body during the long incubation period after infection. to overcome the disadvantage of using the traditional reverse transcription (rt)-pcr in in situ studies, an isothermal nucleic acid sequence-based amplification (nasba) technique was developed for detection of the rabies virus gene. the nasba technique involves the use of 4 enzymatic activities to produce multiple rna copies o ... | 2003 | 14600342 |
| toxicity and antiviral activity of cinnabarin obtained from pycnoporus sanguineus (fr.) murr. | this work describes the cytopathic effect on cells, cytotoxic action on mice, and antiviral activity of cinnabarin. this substance had no effect on mouse neuroblastoma cells (na cell, atcc clone c-1300) at a concentration of 0.31 mg/ml, it was not able to cause toxic effects in mice at concentrations of 1000 mg/kg, and reduced by four times the titers of the rabies virus at concentrations of 0.31 mg/ml. | 2003 | 14595589 |
| apoptosis and rabies virus neuroinvasion. | rabies virus (rv) causes a non-lytic infection of neurons leading to a fatal myeloencephalitis in mammals including humans. by comparing the infection of the nervous system of mice by a highly pathogenic neuroinvasive strain of rv (cvs) and by a strain of attenuated pathogenicity (pv) with restricted brain invasion, we showed that rv neuroinvasiveness results of three factors: not only neurotropic rv avoids induced neuron cell death but also "protective" t cells that migrate into the infected ne ... | 2003 | 14585545 |
| another interpretation of ferret's reaction to vaccination. | 2003 | 14584736 | |
| genetic characterization of rabies field isolates from thailand. | we sequenced 512 nucleotides in two variable regions of the n gene of 23 rabies isolates from the northeastern part of thailand by direct sequencing of pcr-amplified products. the sequencing data revealed two new lineages in these rabies isolates. based on the results of this study together with the findings of our earlier study, the rabies isolates in thailand were divided into two genogroups, designated as t1 and t2, which were predominantly localized in the northern and northeastern areas, re ... | 2003 | 14584612 |
| monoclonal antibody #3-9-16 recognizes one of the two isoforms of rabies virus matrix protein that exposes its n-terminus on the virion surface. | we investigated behaviors of the rabies virus matrix (m) protein using a monoclonal antibody (mab), #3-9-16, that recognized a linear epitope located at the n-terminus of the protein. based on the reactivity with this mab, m proteins could be divided into at least two isoforms; an ordinary major form (malpha) whose 3-9-16 epitope is hidden, and an n-terminal-exposed epitope-positive form (mbeta). the mbeta protein accounted for about 25-30% of the total m proteins in the virion, while its conten ... | 2003 | 14584611 |
| does contact with urine and blood from a rabid dog represent a rabies risk? | 2003 | 14583881 | |
| safe and easy monitoring of anti-rabies antibody in dogs using his-tagged recombinant n-protein. | the virus neutralization (vn) test is a reliable indicator of adequate vaccination in animals. however, the vn test is tedious and complicated to perform. enzyme-linked immunosorbent assay (elisa), though rapid and simple compared to the vn test, is complicated and hazardous during preparation of the viral antigen. in an effort to overcome the disadvantage of elisa, the recombinant his-tagged nucleoprotein (his-rnp) expressed in escherichia coli was used as a safe antigen for elisa (i.e., live v ... | 2003 | 14583639 |
| dissociation of rabies virus matrix protein functions in regulation of viral rna synthesis and virus assembly. | recently, we have shown that the rabies virus (rv) matrix (m) protein regulates the balance of virus rna synthesis by shifting synthesis activity from transcription to replication (s. finke, r. mueller-waldeck, and k. k. conzelmann, j. gen. virol. 84:1613-1621, 2003). here we describe the identification of an m residue critical for regulation of rv rna synthesis. by analyzing the phenotype of heterotypic rv m proteins with respect to rna synthesis of rv sad l16, we identified the m proteins of t ... | 2003 | 14581544 |
| rabies dna vaccine in the horse: strategies to improve serological responses. | in order for dna vaccines to become a practical alternative to conventional vaccines their ability to induce antibody responses in large mammals needs to be improved. we used dna vaccination against rabies in the horse as a model to test the potential of two different strategies to enhance antibody responses in a large mammalian species. the administration of the dna vaccine in the presence of aluminum phosphate improved both the onset and the intensity of serological responses but was not poten ... | 2003 | 14575772 |
| recommendations of a national working group on prevention and control of rabies in the united states. article iii: rabies in wildlife. national working group on rabies prevention and control. | 1999 | 14575027 | |
| population monitoring in support of a rabies vaccination program for skunks in arizona. | three population monitoring methods were evaluated in support of a trap/vaccinate/release program for controlling a bat variant of rabies virus in skunks (mephitis mephitis) in flagstaff, arizona (usa). skunks were the primary species targeted for population monitoring during the program, but feral cats were also monitored as they represented an abundant secondary vector species capable of rabies transmission. skunks were vaccinated and released, except for a subset tested for rabies. all captur ... | 2003 | 14567243 |
| [human cases of hydrophobia in the russian federation]. | the analysis of 29 human cases of hydrophobia registered in the russian federation in 2000-2001 is presented. dogs appeared to be the main infection source (50% of cases). an increased proportion of cats (17.3%) in the spread of the disease was noted. among wild animals, the leading role of foxes in the spread of rabies virus was determined. a number of serious drawbacks in the organization of antirable service to the population, in particular, insufficient qualification of medical personnel, a ... | 2003 | 14565138 |
| nasal trigeminal inputs release the a5 inhibition received by the respiratory rhythm generator of the mouse neonate. | experiments were performed on neonatal mice to analyze why, in vitro, the respiratory rhythm generator (rrg) was silent and how it could be activated. we demonstrated that in vitro the rrg in intact brain stems is silenced by a powerful inhibition arising from the pontine a5 neurons through medullary alpha(2) adrenoceptors and that in vivo nasal trigeminal inputs facilitate the rrg as nasal continuous positive airway pressure increases the breathing frequency, whereas nasal occlusion and nasal a ... | 2004 | 14561692 |
| high level of bcl-2 counteracts apoptosis mediated by a live rabies virus vaccine strain and induces long-term infection. | we report here that rabies virus strains, currently used to immunize wildlife against rabies, induce not only caspase-dependent apoptosis in the human lymphoblastoid jurkat t cell line (jurkat-vect), but also a caspase-independent pathway involving the apoptosis-inducing factor (aif). in contrast, a strain of neurotropic rv that does not induce apoptosis did not activate caspases or induce aif translocation. bcl-2 overproduction in jurkat t cells (jurkat-bcl-2) abolished both pathways. era infec ... | 2003 | 14554083 |
| mucosally delivered e1-deleted adenoviral vaccine carriers induce transgene product-specific antibody responses in neonatal mice. | e1-deleted adenoviral vectors of the human serotype 5 (adhu5) and the chimpanzee serotype 68 (adc68) expressing the rabies virus glycoprotein (rab.gp) were tested for induction of transgene product-specific abs upon intranasal or oral immunization of newborn mice. both vectors induced abs to rabies virus that could be detected in serum and from mucosal secretions. serum rabies virus neutralizing ab titers sufficed to protect neonatally vaccinated mice against a subsequent challenge with rabies v ... | 2003 | 14530353 |
| a system of protein target sequences for anti-rna-viral chemotherapy by a vitamin b6-derived zinc-chelating trioxa-adamantane-triol. | the synthesis of the structurally unusual heterotricyclic compound 1-[3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinyl]-2,8,9-trioxaadamantane-3,5,7-triol (trivially named bananin, bn) from pyridoxylidenephloroglucinol and a theoretical prospect on possible biological activities of bn are presented in this report. pyridoxylidenephloroglucinol is synthesized by knoevenagel condensation of the vitamin b6 aldehyde pyridoxal with phloroglucinol. pyridoxylidenephloroglucinol rearranges to light-yello ... | 2003 | 14527557 |
| improved recovery of rabies virus from cloned cdna using a vaccinia virus-free reverse genetics system. | to improve efficiency of recovery of rabies virus from cloned cdna, we established a bhk cell clone that stably expresses t7 rna polymerase, which we named bhk/t7-9. we also constructed new helper plasmids for expression of nucleoprotein and rna polymerase of the rc-hl strain using the ptm1 plasmid vector, which makes the t7 rna polymerase-transcripts from the plasmid cap-independent for translation. after co-transfection of these helper plasmids and the previously constructed full-length genome ... | 2003 | 14524622 |
| skunk and raccoon rabies in the eastern united states: temporal and spatial analysis. | since 1981, an epizootic of raccoon rabies has spread throughout the eastern united states. a concomitant increase in reported rabies cases in skunks has raised concerns that an independent maintenance cycle of rabies virus in skunks could become established, affecting current strategies of wildlife rabies control programs. rabies surveillance data from 1981 through 2000 obtained from the health departments of 11 eastern states were used to analyze temporal and spatial characteristics of rabies ... | 2003 | 14519253 |
| cell-type-specific gene delivery into neuronal cells in vitro and in vivo. | the avian retroviruses reticuloendotheliosis virus strain a (rev-a) and spleen necrosis virus (snv) are not naturally infectious in human cells. however, rev-a-derived viral vectors efficiently infect human cells when they are pseudotyped with envelope proteins displaying targeting ligands specific for human cell-surface receptors. here we report that vectors containing the gag region of rev-a and pol of snv can be pseudotyped with the envelope protein of vesicular stomatitis virus (vsv) and the ... | 2003 | 14517061 |
| sequence analysis of rabies virus in humans exhibiting encephalitic or paralytic rabies. | two distinct clinical patterns, encephalitic (furious) and paralytic (dumb), have been recognized in human rabies. it has been postulated that different rabies virus variants associated with particular vectors may be responsible for these different clinical manifestations. analysis of the glycoprotein (g), nucleoprotein (n), and phosphoprotein (p) genes of rabies viruses from 2 human cases of encephalitic rabies and from 2 human cases of paralytic rabies demonstrated only minor nucleotide differ ... | 2003 | 14513414 |
| functional human immunodeficiency virus type 1 (hiv-1) gag-pol or hiv-1 gag-pol and env expressed from a single rhabdovirus-based vaccine vector genome. | recombinant rabies virus (rv) vaccine strain-based vectors have been successfully developed as vaccines against other viral diseases (j. p. mcgettigan et al., j. virol. 75:4430-4434, 2001; mcgettigan et al., j. virol. 75:8724-8732, 2001; c. a. siler et al., virology 292:24-34, 2002), and safety concerns have recently been addressed (mcgettigan et al., j. virol. 77:237-244, 2003). however, size limitations of the vectors may restrict their use for development of vaccine applications that require ... | 2003 | 14512539 |
| oral vaccination of mice with adenoviral vectors is not impaired by preexisting immunity to the vaccine carrier. | adenovirus vectors with e1 deleted of the human serotype 5 (adhu5) and the chimpanzee serotype 68 (adc68) expressing the glycoprotein of the evelyn rokiniki abelseth strain of rabies virus were tested upon oral application for induction of systemic and mucosal transgene product-specific antibody responses in mice. both vectors induced systemic and mucosal antibodies to rabies virus, including virus-neutralizing antibodies and protection against a severe intracerebral challenge with a mouse-adapt ... | 2003 | 14512528 |
| rabies in wildlife in latvia. | in the baltic states, lyssaviruses are often detected in wildlife and presumed to constitute an important public health hazard. in order to decrease rabies incidence and eradicate wildlife reservoirs, a national rabies eradication program has been in place. since 1970 a vaccination program in dogs and cats has been executed, and in 1991 oral vaccination of foxes was started. however, due to an insufficient budget, the latter was not done regularly and nationwide before 2000. now, the program in ... | 2003 | 14511581 |
| mccoy cell line as a possible model containing cd4+ receptors for the study of hiv-1 replication. | several studies have recently shown the use of recombinant rabies virus as potential vector-viral vaccine for hiv-1. the sequence homology between gp 120 and rabies virus glycoprotein has been reported. the mccoy cell line has therefore been used to show cd4+ or cd4+ like receptors. samples of hiv-1 were isolated, when plasma of hiv-1 positive patients was inoculated in the mccoy cell line. the virus infection was then studied during successive virus passages. the proteins released in the extra ... | 2003 | 14502348 |
| studies on the pathogenesis of rabies. | in experiments on the pathogenesis of rabies, mice were challenged intracerebrally and intramuscularly with rabies virus and groups of the animals were sacrificed immediately and at various intervals after challenge and the virus content of several organs estimated. the influence of the site of injection on the duration of incubation and the effect of antirabies serum on the virus in the brain and in the skeletal muscle were also investigated.the results of these experiments indicate that shortl ... | 1961 | 14498436 |
| electron microscopy of nerve cells infected with street rabies virus. | 1962 | 14471291 | |
| [presence of specific inclusions in hamster kidney cells in tissue culture infected by fixed rabies virus (louis pasteur strain). kinetic study of the virus]. | 1961 | 14470606 | |
| studies on the local treatment of wounds for the prevention of rabies. | this paper reports on laboratory studies made in guinea-pigs on puncture wounds infected with fixed rabies virus and treated one hour later with various substances, the purpose being to review the experience of previous workers and to explore new approaches to the problem of local treatment of wounds inflicted by rabid animals.among the measures affording greater or lesser protection were: nitric acid cauterization; direct application of benzalkonium chloride to the wound or its infiltration, as ... | 1962 | 14453773 |
| [note on the prolonged incubation or the latency of the rabies virus. study of the flury strain.--observation and discussion]. | 1959 | 14433379 | |
| [development of a method for the inactivation of anti-rabies vaccine with ultraviolet rays. i. effect of various conditions of action of ultraviolet rays on the infectious and immunogenic properties of fixed rabies virus]. | 1959 | 14433266 | |
| [behavior of the arrest phenomenon in animals infected with fixed rabies virus and subjected to fractionated controlled hypothermia]. | 1959 | 14420104 | |
| [the arrest phenomenon in the white rat infected with fixed rabies virus and subjected to controlled hypothermia 48 hours before the onset of paralysis]. | 1959 | 14420102 | |
| [histological featurs of rabies virus of bats in yugoslavia]. | 1959 | 14407028 | |
| attempts to immunize guinea pigs with flury vaccine and subsequent challenge with fixed rabies virus. | 1959 | 14405673 | |
| quantitative determination of the dissemination of flury rabies virus in the central nervous system of the guinea-pig after intramuscular inoculation in the hind leg. | 1959 | 14405670 | |
| an indicator plaque-forming system for demonstration of interference by non-cytocidal strains of rabies virus. | 1960 | 14404412 | |
| demonstration of rabies virus in tissue culture with fluorescent antibody technique. | 1960 | 14404411 | |
| human antirabies gamma globulin. | to obviate the foreign protein reactions experienced with the use of hyperimmune serum in rabies-exposed individuals, an attempt was made to produce a rabies antiserum of human origin.five doses of an inactivated rabies virus duck-egg vaccine were administered to 34 volunteers at 4-day intervals (i.e., on days 0, 4, 8, 12 and 16). an additional dose of chick-embryo attenuated virus vaccine-flury hep (high egg passage)-was given on the 46th day, followed by a final booster dose of duck-egg vaccin ... | 1959 | 14403320 |
| bentonite purification of certain viruses. | 1955 | 14388338 | |
| studies by electron microscopy of a fixed (pasteur) rabies virus, a street rabies virus and the egg adapted flury strain of rabies. | 1955 | 14386419 | |
| isolation of rabies virus from an insectivorous bat (tadarida mexicana) in california. | 1955 | 14384888 | |
| a report on research at mississippi state penitentiary. | 1955 | 14369963 | |
| early appearance of rabies virus in the blood of cave bats exposed by intraperitoneal injection. | 1955 | 14365174 | |
| [considerations on the mechanism of action of the pasteur rabies virus-vaccine and on the mechanism of rabies immunity]. | 1954 | 14358007 | |
| [stabilization of fixed rabies virus]. | 1954 | 14349265 | |
| [culture of rabies virus and its multiplication in bhk-21c-13 cells]. | 1965 | 14328265 | |
| laboratory investigation of arctic strains of rabies virus. | 1965 | 14324666 | |
| electrophoresis study of extracts of submaxillary salivary glands from naturally rabid dogs. | rabies virus in submaxillary salivary glands from naturally infected dogs was investigated by a paper electrophoresis technique, and the virus activity was quantitated by intracerebral titration in mice. extracts from these salivary glands were found to contain (a) 10(4) to 10(6) mouse icld (50) units of wild rabies seed and (b) a protein complex that migrated electrophoretically in the albumin band and more conspicuously in the beta and gamma bands of normal horse serum. the protein complex was ... | 1965 | 14318538 |
| excretion of street rabies virus in the saliva of dogs. | 1965 | 14313891 | |
| [fixed rabies virus and interferon]. | 1965 | 14305448 | |
| accumulation of specific antigen and distribution of nucleic acids in sheep embryo kidney cells infected with street rabies virus as revealed by fluorescence microscopy. | 1965 | 14303938 | |
| effects of cortisone on in vitro viral infection. i. inhibition of cytopathogenesis by polio, rabies and yellow fever viruses in human embryonic cells. | 1965 | 14297833 | |
| purification of fixed rabies virus. | 1965 | 14297214 | |
| simultaneous growth of rabies and canine distemper viruses in chick embryos. | rabies virus and canine distemper virus were grown simultaneously, and possibly symbiotically, in the same chick embryos. there seemed to be no adverse effect on either virus when cultured in such manner.bivalent vaccines for rabies and canine distemper were produced. the potencies and the virus titers of such vaccines were comparable to those of rabies vaccine and canine distemper vaccine produced separately. | 1965 | 14290942 |
| paper electrophoresis study of sera of dogs immune to wild rabies virus. | three hyperimmune dogs were injected intramuscularly with canine wild rabies virus. the dogs showed no clinical evidence of rabies. intramuscular injection of the wild rabies virus in susceptible puppies induced fulminating disease and mortality in 14 to 16 days. investigation of the serum proteins of the hyperimmune dogs by a paper electrophoresis technique revealed conspicuous changes in the beta and gamma protein bands. | 1965 | 14281077 |
| advances in rabies research. | 1964 | 14269511 | |
| tissue-culture rabies vaccine (flury lep) in dogs. | 1965 | 14266931 | |
| study of factors affecting the yield of rabies virus in tissue culture. | 1964 | 14247631 | |
| propagation of rabies fixed virus in tissue culture. | 1964 | 14247630 | |
| electron microscopic studies of mouse brain infected with street rabies virus. | 1964 | 14246008 | |
| endosymbiotic relationship between animal viruses and host cells. a study of rabies virus in tissue culture. | re cultures infected with a fixed rabies virus were studied. the virus can propagate itself in these cells for an indefinite period of time without interfering with cell growth. the present study characterizes this truly endosymbiotic relationship. virus-specific antigen was detected in the cytoplasm of each cell by fluorescein-labeled antirabies serum but only 4 to 5 per cent of the cells released infectious virus. all cells undergoing division showed viral antigen throughout the mitotic proces ... | 1964 | 14238928 |
| [multiplication of rabies virus (flury hep strain) on hog kidney cells in continuous culture (abstract)]. | 1964 | 14227593 | |
| [development and diffusion of the rabies virus (flury hep strain) in embryonated egg and its multiplication on trypsinized cells of infected chick embryo (abstract)]. | 1964 | 14227592 | |
| cultivation of rabies virus in human diploid cell strain wi-38. | 1964 | 14218592 | |
| [infection of dog sub-maxillary gland cells cultivated in vitro by a fixed rabies virus]. | 1964 | 14206890 | |
| the development of fixed rabies virus in mouse brain. | 1964 | 14202185 | |
| [on viruses isolated from patients with encephalomyelitis and multiple sclerosis. i. pathogenic and antigenic properties of the isolated viruses]. | 1964 | 14195994 | |
| cytochemistry of inclusion bodies in tissue culture cells infected with rabies virus. | 1964 | 14194600 | |
| studies with cultured brown adipose tissue. ii. influence of low temperature on rabies virus infection in bat brown fat. | 1964 | 14192767 | |
| studies with cultured brown adipose tissue. i. persistence of rabies virus in bat brown fat. | 1964 | 14192763 | |
| abortive rabies infection. i. experimental production in white mice and general discussion. | 1964 | 14183397 | |
| summary of rabies outbreak in maine. | 1964 | 14180684 | |
| [rabies]. | 1964 | 14175335 | |
| properties of the nucleic acids from some herpes group viruses. | 1964 | 14165337 | |
| [allergic encephalomyelitis and intermediate antigens of nerve tissues infected with viruses]. | 1964 | 14164801 | |
| antirabies antibody response in man to vaccine made from infected suckling-mouse brains. | antirabies vaccines produced from infected brains of adult mammals have always had the potentiality of causing post-vaccinal paralysis or allergic encephalitis in man. attempts in recent years either to remove the paralytic factor from brain-tissue vaccines or to use as the virus source infected tissue other than nervous tissue (e.g., chick embryos) have usually resulted in a substantial reduction of the specific antirabies potency.the authors' laboratory had previously developed a vaccine made ... | 1964 | 14163964 |
| ascites tumours from bhk.21 cells transformed in vitro by polyoma virus. | 1964 | 14161203 | |
| observations on erythrocytic inclusion bodies from mice infected with rabies virus. | 1964 | 14155799 | |
| a csee of rabies in england. | 1964 | 14150893 |