Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
|---|
| in vivo bubble nucleation probability in sheep brain tissue. | gas nuclei exist naturally in living bodies. their activation initiates cavitation activity, and is possible using short ultrasonic excitations of high amplitude. however, little is known about the nuclei population in vivo, and therefore about the rarefaction pressure required to form bubbles in tissue. a novel method dedicated to in vivo investigations was used here that combines passive and active cavitation detection with a multi-element linear ultrasound probe (4-7 mhz). experiments were pe ... | 2011 | 22015981 |
| The effect of maternal linseed supplementation and/or lamb linseed supplementation on muscle and subcutaneous adipose tissue fatty acid composition of indoor lambs. | Eighty eight lambs were used in a 2×2 factorial arrangement 1) to investigate the effect of maternal dietary linseed supplementation and/or lamb linseed supplemented concentrate on growth performance, carcass fat quality and fatty acid (FA) composition of muscle and dorsal adipose tissue of indoor lambs 2) to study the relationships between subcutaneous fat quality and FA composition. Feeding linseed to ewes increased C18:3 n-3 (ALA) proportion in milk and therefore the ALA supply to suckling la ... | 2012 | 22014835 |
| group decision-making in chacma baboons: leadership, order and communication during movement. | group coordination is one of the greatest challenges facing animals living in groups. obligatory trade-offs faced by group members can potentially lead to phenomena at the group level such as the emergence of a leader, consistent structure in the organization of individuals when moving, and the use of visual or acoustic communication. this paper describes the study of collective decision-making at the time of departure (i.e. initiation) for movements of two groups of wild chacma baboons (papio u ... | 2011 | 22014356 |
| α-tocopherol succinate protects mice against radiation-induced gastrointestinal injury. | the purpose of this study was to elucidate the role of α-tocopherol succinate (α-ts) in protecting mice from gastrointestinal syndrome induced by total-body irradiation. cd2f1 mice were injected subcutaneously with 400 mg/kg of α-ts and exposed to different doses of (60)co γ radiation, and 30-day survival was monitored. jejunum sections were analyzed for crypts and villi, puma (p53 upregulated modulator of apoptosis), and apoptosis (terminal deoxynucleotidyl transferase dutp nick end labeling - ... | 2011 | 22013885 |
| Antibody repertoire development in fetal and neonatal piglets. XX. B cell lymphogenesis is absent in the ileal Peyer's patches, their repertoire development is antigen dependent, and they are not required for B cell maintenance. | The continuous ileal Peyer's patches (IPP) of sheep are regarded as a type of mammalian bursal equivalent where B cells diversify their repertoire in an Ag-independent fashion. Anatomically and developmentally similar IPP occur in swine. Resection of ~90% of the IPP in piglets at birth did not alter Ig levels in serum and secretions or retard diversification of the Ab repertoire when animals were maintained in isolators and colonized with a defined gut flora. Resection or sham surgery elevated I ... | 2011 | 22013126 |
| ileal peyer's patches are not necessary for systemic b cell development and maintenance and do not contribute significantly to the overall b cell pool in swine. | based on studies of sheep, ileal peyer's patches (ipp) have been regarded as a type of primary lymphoid tissue similar to the bursa of fabricius in chicken. because bursectomy results in b cell deficiency, we wondered whether resection of the ipp of piglets would have a similar effect. comparison of ipp-resected, surgical shams and untreated germ-free piglets, all of which were later colonized with a defined commensal flora, demonstrated that resection of the ipp did not alter the level and phen ... | 2011 | 22013120 |
| the oral secretion of infectious scrapie prions occurs in preclinical sheep with a range of prnp genotypes. | preclinical sheep with the highly scrapie-susceptible vrq/vrq prnp genotype secrete prions from the oral cavity. in order to further understand the significance of orally available prions, buccal swabs were taken from sheep with a range of prnp genotypes and analyzed by serial protein misfolding cyclic amplification (spmca). prions were detected in buccal swabs from scrapie-exposed sheep of genotypes linked to high (vrq/vrq and arq/vrq) and low (arr/vrq and ahq/vrq) lymphoreticular system involv ... | 2012 | 22013047 |
| combining us and brazilian microsatellite data for a meta-analysis of sheep (ovis aries) breed diversity: facilitating the fao global plan of action for conserving animal genetic resources. | microsatellites are commonly used to understand genetic diversity among livestock populations. nevertheless, most studies have involved the processing of samples in one laboratory or with common standards across laboratories. our objective was to identify an approach to facilitate the merger of microsatellite data for cross-country comparison of genetic resources when samples were not evaluated in a single laboratory. eleven microsatellites were included in the analysis of 13 us and 9 brazilian ... | 2011 | 22013019 |
| transvaginal notes-assisted laparoscopic nephrectomy: a survival study in a sheep model. | background: this study aims to evaluate the feasibility and usefulness of an ovine model in order to perform natural orifice translumenal endoscopic surgery (notes) approach and laparoscopic nephrectomy for research and training purposes. methods: ten healthy female sheep were used to perform transvaginal notes-assisted right laparoscopic nephrectomy using a flexible 12-mm gastroscope through a vaginal access and ... | 2011 | 22011949 |
| long-term increase in uterine blood flow is achieved by local overexpression of vegf-a(165) in the uterine arteries of pregnant sheep. | increasing uterine artery blood flow (uabf) may benefit fetal growth restriction where impaired uteroplacental perfusion prevails. based on previous short-term results, we examined the long-term effects of adenovirus vector-mediated overexpression of vascular endothelial growth factor-a(165) (vegf-a(165)) in the uterine artery (uta). transit-time flow probes were implanted around both utas of mid-gestation pregnant sheep (n=11) to measure uabf. a carotid artery catheter was inserted to measure m ... | 2011 | 22011641 |
| When balanced for precursor fatty acid supply echium oil is not superior to linseed oil in enriching lamb tissues with long-chain n-3 PUFA. | Vegetable oils containing stearidonic acid (SDA, 18 : 4n-3) are considered better precursors of long-chain n-3 PUFA (LC n-3 PUFA) than those with only a-linolenic acid (ALA, 18 : 3n-3). The present study re-examined this premise using treatments where added ALA from linseed oil was matched with ALA plus SDA from echium oil. Lambs (n 6) were abomasally infused with saline (control (C), 25 ml), echium oil low (EL, 25 ml), echium oil high (EH, 50 ml), linseed oil low (LL, 25 ml) or linseed oil high ... | 2011 | 22011528 |
| A novel method for quantifying in-vivo regional left ventricular myocardial contractility in the border zone of a myocardial infarction. | Homogeneous contractility is usually assigned to the remote region, border zone (BZ), and the infarct in existing infarcted left ventricle (LV) mathematical models. Within the LV, the contractile function is therefore discontinuous. Here, we hypothesize that the BZ may in fact define a smooth linear transition in contractility between the remote region and the infarct. To test this hypothesis, we developed a mathematical model of a sheep LV having an anteroapical infarct with linearly-varying BZ ... | 2011 | 22010752 |
| [osseointegration of ceramic cement-free acetabular cups.] | introduction: a stable osseointegration of an alumina-matrix-composite-ceramic (amc) could facilitate the use of a thin-walled monoblock acetabular cup for hip arthroplasty with large ball-heads providing advantages like reduced risk of dislocation. the aim of the pilot study was to examine the osseointegration of porous-coated alumina-matrix-composite-ceramic-monoblock cups after implantation in a sheep model. material and methods: the porous coated amc-ceramic cups were taken out after a heal ... | 2011 | 22009586 |
| Antigenic mimicry-mediated anti-prion effects induced by bacterial enzyme succinylarginine dihydrolase in mice. | Prions, the causative agents of prion diseases, are immunologically tolerated because their major component, prion protein (PrP), is a host-encoded molecule. Therefore, no effective prion vaccines have been developed. We previously showed that heterologous bovine and sheep PrP immunizations of mice overcame tolerance by an antigenic mimicry mechanism to efficiently induce anti-PrP auto-antibodies (Abs), significantly prolonging incubation times in mice subsequently infected with the mouse-adapte ... | 2011 | 22008817 |
| isolation and culture of preantral follicles for retrieving oocytes for the embryo production: present status in domestic animals. | the development of efficient ovarian preantral follicle (pf) isolation and culture systems provide a large number of oocytes for the manipulation and embryo production. it also helps for understanding the mechanisms of follicle and oocyte development. isolation and culture protocols for pfs were developed for many domestic species like cattle, buffalo, sheep, goat, pig, horse, camel, dog and cats; however, embryo production from oocytes derived from in vitro grown pfs was reported only in pigs, ... | 2011 | 22008238 |
| Review of neurological diseases of ruminant livestock in Australia. VI: postnatal bovine, and ovine and caprine, neurogenetic disorders. | This paper, the last in a series of reviews of neurological diseases of ruminants in Australia, discusses a range of neurogenetic disorders of cattle, sheep and goats, including necrotising encephalomyelopathy, glycogen storage disorders, cerebellar abiotrophy and ß-mannosidosis. They are categorised by the species and breeds in which they occur. | 2011 | 22008121 |
| research using unregistered analgesics in sheep. | 2011 | 22008118 | |
| prion protein polymerisation triggered by manganese-generated prion protein seeds. | prion diseases are neurodegenerative diseases that can be transmitted between individuals. the exact cause of these diseases remains unknown. however, one of the key events associates with the disease is the aggregation of a cellular protein, the prion protein. the mechanism of this is still unclear. however, it is likely that the aggregation is trigged by a seeding mechanism in which an oligomer of the prion protein is able to catalyse polymerisation of further prion protein into larger aggrega ... | 2012 | 22007749 |
| improved transnasal transport and brain uptake of tizanidine hcl-loaded thiolated chitosan nanoparticles for alleviation of pain. | the aim of this study was to prepare and characterize thiolated chitosan (tc) nanoparticles (nps) of tizanidine hcl (tz) and to evaluate its transport across monolayer of rpmi 2650 cells (human nasal septum carcinoma cell line) followed by assessment of their pharmacokinetic and pharmacodynamic attributes, after intranasal (i.n.) administration. chitosan was thiolated by carbodiimide method and thiolation was confirmed qualitatively and quantitatively. nps were prepared using ionotropic gelation ... | 2011 | 22006260 |
| a swine model of neonatal asphyxia. | annually more than 1 million neonates die worldwide as related to asphyxia. asphyxiated neonates commonly have multi-organ failure including hypotension, perfusion deficit, hypoxic-ischemic encephalopathy, pulmonary hypertension, vasculopathic enterocolitis, renal failure and thrombo-embolic complications. animal models are developed to help us understand the patho-physiology and pharmacology of neonatal asphyxia. in comparison to rodents and newborn lambs, the newborn piglet has been proven to ... | 2011 | 22006174 |
| propagating and detecting an infectious molecular clone of maedi-visna virus that expresses green fluorescent protein. | maedi-visna virus (mvv) is a lentivirus of sheep, causing slowly progressive interstitial pneumonia and encephalitis. the primary target cells of mvv in vivo are considered to be of the monocyte lineage. certain strains of mvv can replicate in other cell types, however. the green fluorescent protein is a commonly used marker for studying lentiviruses in living cells. we have nserted the egfp gene into the gene for dutpase of mvv. the dutpase gene is well conserved in most lentivirus strains of s ... | 2011 | 22005550 |
| co-circulation of bluetongue and epizootic haemorrhagic disease viruses in cattle in reunion island. | bluetongue virus (btv) and epizootic haemorrhagic disease virus (ehdv) in deer have already been isolated in reunion island and have caused more or less severe clinical signs in cattle (ehdv) or in sheep (btv), as observed in 2003. in january 2009, cattle in reunion island showed clinical signs suggesting infection by one or the other of these arboviral diseases. a study was set up to determine the etiology of the disease. analysis by reverse transcriptase-polymerase chain reaction (rt-pcr) perf ... | 2011 | 22005178 |
| effect of young maternal age and skeletal growth on placental growth and development. | teenagers are susceptible to delivering small-for-gestational-age infants. previous studies implicate continued skeletal growth as a contributory factor, and impaired placental development was the primary cause of fetal growth restriction in growing adolescent sheep. the aims of this study were to examine the impact of young maternal age and growth on placental development. | 2011 | 22005108 |
| unstable pyrethroid resistance in sheep body lice bovicola ovis (schrank), (phthiraptera: trichodectidae) and its implications for lice control on sheep. | a retrospective study in which the 18years treatment history of a mob of sheep hosting a pyrethroid resistant strain of sheep body lice was compared with the coincidental changes in that strain's response to cypermethrin, provided a unique opportunity to investigate the stability of pyrethroid resistance in this species. resistance levels remained very high (resistance factors (rf)=75-145) for at least five years following the cessation of pyrethroid treatments but within ten years had dropped t ... | 2011 | 22004914 |
| influence of feeding mediterranean food industry by-products and forages to awassi sheep on physicochemical properties of milk, yoghurt and cheese. | feeding agro-industrial by-products and unconventional forages, rich in potentially anti-nutritional factors, may influence the quality of the raw milk and the dairy products prepared therefrom. the aim of the present study was to determine side-effects on physicochemical properties of milk, yoghurt and cheese of feeding diets where one third were feeds either rich in lipids (tomato pomace and olive cake) or phenols (olive leaves and lentil straw) or electrolytes (atriplex leaves). the diets, in ... | 2011 | 22004605 |
| Automated planning of computer assisted mosaic arthroplasty. | We describe and evaluate a computer algorithm that automatically develops a surgical plan for computer assisted mosaic arthroplasty, a technically demanding procedure in which a set of osteochondral plugs are transplanted from a non-load-bearing area of the joint to the site of a cartilage defect. We found that the algorithm produced plans that were at least as good as a human expert, had less variability, and took less time. | 2011 | 22003626 |
| distribution of lesions in fetal brains following experimental infection of pregnant sheep with toxoplasma gondii. | six ovine fetal brains were harvested 33 to 35 days postchallenge from 5 ewes, each of which was given 3000 toxoplasma gondii oocysts on day 90 of pregnancy. histopathologic examination of transverse sections taken at 13 levels in the fetal brains revealed the presence of toxoplasmosis-related lesions in all 6 brains. however, lesions were not randomly distributed (p = .007); they were most numerous at the level of the optic tract, the rostral margin of the pons, and 4 mm caudal to the ansate su ... | 2011 | 22002976 |
| age estimation of museum wool textiles from ovis aries using deamidation rates utilizing matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. | cultural heritage contains a large number of precious proteinaceous specimens, such as wool and silk textiles, leather objects, paper, paint, coatings, binders (and associated adhesives), etc. to minimize the degradation of and to preserve these artifacts, it is desirable to understand the fundamental factors that cause their degradation, to identify the deterioration markers that determine their degradation stage and their age, and to use technologies that can provide this information rapidly w ... | 2011 | 22002692 |
| supplementing endophyte-infected tall fescue or reed canarygrass with alfalfa or birdsfoot trefoil increases forage intake and digestibility by sheep. | background: we hypothesized that alfalfa (alf) or birdsfoot trefoil (bft) eaten prior to a meal of endophyte-infected tall fescue (tf) or reed canarygrass (rcg) would provide benefits not possible when tf or rcg are eaten alone. in trial 1, four groups of five lambs were first offered alf for 30 min followed by either tf or rcg for 3.5 h in a 2 × 2 factorial arrangement of a completely randomized design that included grass (tf or rcg) with or without alf. trial 2 was similar to trial 1 except we ... | 2011 | 22002685 |
| Delayed cortical impairment following lipopolysaccharide exposure in preterm fetal sheep. | Preterm infants exhibit chronic deficits in white matter (WM) and cortical maturation. Although fetal infection/inflammation may contribute to WM pathology, the factors contributing to cortical changes are largely unknown. We examined the effect of fetal lipopolysaccharide (LPS) exposure on WM and cortical development as assessed by magnetic resonance imaging (MRI), electroencephalography (EEG), and histopathology in fetal sheep at preterm human equivalent age. | 2011 | 22002627 |
| importation of johne's disease vaccine. | 2011 | 22001812 | |
| translocators yopb and yopd from yersinia enterocolitica form a multimeric integral membrane complex in eukaryotic cell membranes. | the type iii secretion systems are contact-activated secretion systems that allow bacteria to inject effector proteins across eukaryotic cell membranes. the secretion apparatus, called injectisome or needle complex, includes a needle that terminates with a tip structure. the injectisome exports its own distal components, like the needle subunit and the needle tip. upon contact, it exports two hydrophobic proteins called translocators (yopb and yopd in yersinia enterocolitica) and the effectors. ... | 2011 | 22001511 |
| inherited junctional epidermolysis bullosa (herlitz type) in german black-headed mutton sheep. | this report describes the microscopical, immunohistochemical and ultrastructural findings in the first ovine cases of the herlitz type of inherited junctional epidermolysis bullosa. sixteen german black-headed mutton lambs and one crossbred lamb had blisters and ulceration of the skin and mucous membranes in addition to alterations of the horn of the hooves. microscopically, there was separation of the dermoepidermal junction, which was confirmed to be located in the lamina lucida of the basemen ... | 2011 | 22000950 |
| [In vivo imaging of ram spermatozoa in the ewe genital tract using fibered confocal microscopy]. | Sperm transit in the female tract is one of the key factors in the success of fertilization after artificial insemination in sheep species. However, its study is limited by the absence of in vivo imaging methods. The imaging of ram sperm in the female genital tract was made possible using the confocal fibered microscopy and fluorescent stains adapted to spermatozoa. Our results show the active role of the uterotubal junction in the selection of sperm during their transit. | 2011 | 22000831 |
| Increased Immunohistochemical Labelling for Prion Protein Occurs in Diverse Neurological Disorders of Sheep: Relevance for Normal Cellular PrP Function. | The classical prion diseases (e.g. scrapie of sheep and goats and bovine spongiform encephalopathy of cattle) are characterized by the accumulation of abnormal forms of the prion protein (PrP), usually recognized by their relative resistance to proteolysis compared with the physiological cellular forms of PrP. However, novel prion diseases have been detected in sheep, cattle and man, in which the abnormal PrP has less resistance to proteolysis than identified previously. These more subtle differ ... | 2011 | 22000036 |
| immunophenotype of cells within cervine rectoanal mucosa-associated lymphoid tissue and mesenteric lymph nodes. | rectoanal mucosa-associated lymphoid tissue (ramalt) is a part of the lymphoid system that can be sampled easily in live animals, especially ruminants. ramalt biopsy is useful for the diagnosis of transmissible spongiform encephalopathies, including scrapie in sheep and goats and chronic wasting disease (cwd) in cervids. diagnosis is reliant on detection of abnormal prion protein (prp(d)), which is associated with lymphoid follicles. for enzyme linked immunosorbent assays (elisas) detecting prp( ... | 2011 | 22000034 |
| ammonia emissions during vermicomposting of sheep manure. | the effect of c:n ratio, temperature and water content on ammonia volatilization during two-phase composting of sheep manure was evaluated. the aerobic phase was conducted under field conditions. this was followed by phase ii, vermicomposting, conducted in the laboratory under controlled conditions of water content (70% and 80%) and temperature (15 and 22 °c). the addition of extra straw lead to a 10% reduction in nh3 volatilization compared to sheep manure composted without extra straw. tempera ... | 2011 | 21996478 |
| Morphological characteristics of Echinococcus granulosus derived from buffalo in Iran. | SUMMARYCystic echinococcosis is a significant parasitic disease in Iran, where a variety of animals act as intermediate hosts. In this study, 25 isolates of Echinococcus granulosus obtained from water buffalo from various parts of Iran were characterized on the basis of the morphology of the metacestode and the adult worm. The characteristics of protoscoleces from the different studied areas were nearly similar. They showed 2 rows of alternating large and small hooks and their shapes were smooth ... | 2011 | 21996421 |
| Identification of meat species by PCR-RFLP of the mitochondrial COI gene. | Meat authenticity verification is pertinent for economical, religious or public health concerns. The present study investigates the use of PCR-RFLP of a part of the mitochondrial cytochrome c oxidase subunit 1 (COI) gene for identification of species origin of raw meat samples of cow, chicken, turkey, sheep, pig, buffalo, camel and donkey. PCR yielded a 710-bp fragment in all species. The amplicons were digested with seven restriction endonucleases (Hind II, Ava II, Rsa I, Taq I, Hpa II, Tru 1I ... | 2012 | 21996288 |
| chaperonin tric assists the refolding of sperm-specific glyceraldehyde-3-phosphate dehydrogenase. | the cytosolic chaperonin tric was isolated from ovine testes using ultracentrifugation and heparin-sepharose chromatography. the molecular mass of the obtained preparation was shown to exceed 900 kda (by blue native page). sds-page yielded a set of bands in the range of 50-60 kda. electron microscopy examination revealed ring-shaped complexes with the outer diameter of 15 nm and the inner diameter of approximately 6 nm. the results suggest that the purified chaperonin is an oligomeric complex co ... | 2011 | 21995946 |
| involvement of neuronal nitric oxide synthase (nnos) in the regulation of migrating motor complex (mmc) in sheep. | the objectives of this study were to evaluate the role of nitric oxide (no) synthase isoforms (nnos, enos, and inos) in the regulation of the migrating motor complex (mmc) in sheep using electromyography and their expression in the gastrointestinal (gi) tract by western blot (wb) and immunohistochemistry. intravenous administration of l-name or the nnos inhibitor 7-nitroindazole (7-ni) decreased the mmc interval. myoelectric activity of intestinal phase ii was increased, whereas antral activity ... | 2011 | 21995890 |
| jaagsiekte sheep retrovirus biology and oncogenesis. | jaagsiekte sheep retrovirus (jsrv) is the causative agent of a lung cancer in sheep known as ovine pulmonary adenocarcinoma (opa). the disease has been identified around the world in several breeds of sheep and goats, and jsrv infection typically has a serious impact on affected flocks. in addition, studies on opa are an excellent model for human lung carcinogenesis. a unique feature of jsrv is that its envelope (env) protein functions as an oncogene. the jsrv env-induced transformation or oncog ... | 2010 | 21994634 |
| effect of prp genotype and route of inoculation on the ability of discriminatory western blot to distinguish scrapie from sheep bovine spongiform encephalopathy. | procedures for discriminating scrapie from bovine spongiform encephalopathy (bse) in sheep are relevant to ascertain whether bse has entered the sheep population. this study was aimed at investigating whether the suitability of an official eu discriminative method is affected by the sheep prp genotype and route of infection. | 2011 | 21994325 |
| Lousicidal activity of synthesized silver nanoparticles using Lawsonia inermis leaf aqueous extract against Pediculus humanus capitis and Bovicola ovis. | In the present work, we describe inexpensive, nontoxic, unreported and simple procedure for synthesis of silver nanoparticles (Ag NPs) using leaf aqueous extract of Lawsonia inermis as eco-friendly reducing and capping agent. The aim of the present study was to assess the lousicidal activity of synthesized Ag NPs against human head louse, Pediculus humanus capitis De Geer (Phthiraptera: Pediculidae), and sheep body louse, Bovicola ovis Schrank (Phthiraptera: Trichodectidae). Direct contact metho ... | 2011 | 21993881 |
| enhanced central and conduit pulmonary arterial reservoir function offsets reduced ductal systolic outflow during constriction of the fetal ductus arteriosus. | constriction of the fetal ductus arteriosus (da) has disparate effects on mean and phasic hemodynamics, as mean da blood flow is preserved until constriction is severe, but da systolic and diastolic blood velocities change with only mild constriction. to determine the basis of this disparity and its physiological significance, seven anesthetized late-gestation fetal sheep were instrumented with pulmonary trunk (pt), da, and left pulmonary artery (pa) micromanometer catheters and transit-time flo ... | 2012 | 21993527 |
| comparative efficacy of live replicating sheeppox vaccine strains in ovines. | in the present study, two sheeppox vaccines made from strains [sheeppox virus-srinagar (sppv-srin) and ranipet (sppv-r)] indigenous to india and adapted to vero cells were compared in terms of their safety, potency, efficacy and antigenic value with the commercial in-use roumanian fanar (sppv-rf) vaccine, a foreign strain adapted in primary lamb testes cells. the safety test indicated that the sppv (sri and rf) vaccines were safe while sppv-r was not completely attenuated and caused excessive ad ... | 2011 | 21993305 |
| seroprevalence and risk factors associated with visna/maedi virus in semi-intensive lamb-producing flocks in northwestern spain. | a cross-sectional study was carried out to determine visna/maedi virus (vmv) seroprevalence and risk factors in semi-intensive lamb-producing flocks as a prelude to establishing a monitoring program in northwestern (nw) spain. a total of 15,155 serum samples were taken from 78 commercial flocks and were submitted to an indirect vmv elisa. association between potential risk factors and seroprevalence at the flock level was assessed using a multivariable logistic regression model. a generalized es ... | 2012 | 21993274 |
| The genome diversity and karyotype evolution of mammals. | ABSTRACT: The past decade has witnessed an explosion of genome sequencing and mapping in evolutionary diverse species. While full genome sequencing of mammals is rapidly progressing, the ability to assemble and align orthologous whole chromosome regions from more than a few species is still not possible. The intense focus on building of comparative maps for companion (dog and cat), laboratory (mice and rat) and agricultural (cattle, pig, and horse) animals has traditionally been used as a means ... | 2011 | 21992653 |
| in vivo study of flow-rate accuracy of the medstream programmable infusion system. | flow-rate accuracy and precision are important parameters to optimizing the efficacy of programmable intrathecal (it) infusion pump delivery systems. current programmable it pumps are accurate within ±14.5% of their programmed infusion rate when assessed under ideal environmental conditions and specific flow-rate settings in vitro. we assessed the flow-rate accuracy of a novel programmable pump system across its entire flow-rate range under typical conditions in sheep (in vivo) and nominal condi ... | 2011 | 21992246 |
| influence of high-altitude grazing on bone metabolism of growing sheep. | the objective of this study was to identify the effect of high alpine grazing, associated with varying pasture grass qualities and more pronounced exercise on typically steep slopes, on bone metabolism by improving bone density and enhancing bone turnover in growing sheep. twenty-four 5-month-old sheep were randomly assigned to two groups. one group was kept at high altitude (ha; 2000-2200 m a.s.l.) for 3 months, and the other group (c; control) remained in the lowlands (400 m a.s.l.). both grou ... | 2011 | 21992062 |
| Novel intracranial brain cooling catheter to mitigate brain injuries. | Background The neuroprotective effects of cooling the spinal cord in a sheep model by a self-contained intrathecal catheter was reported recently by the authors. The present study was designed to determine if cooling catheters in the lateral ventricles of the brain can effectively cool the CSF and thereby reduce brain temperature while maintaining systemic normothermia. Methods The cooling catheter is a self-contained system that circulates a cold fluid and cools the CSF that circulates in the ... | 2011 | 21990455 |
| comparison of lidocaine, lidocaine/epinephrine or bupivacaine for thoracolumbar paravertebral anaesthesia in fat-tailed sheep. | to evaluate the speed of onset and duration of loss of sensation in the flank following paravertebral administration of lidocaine (with or without epinephrine) or bupivacaine. | 2011 | 21988816 |
| White-tailed deer are susceptible to the agent of sheep scrapie by intracerebral inoculation. | ABSTRACT: Interspecies transmission studies afford the opportunity to better understand the potential host range and origins of prion diseases. The purpose of this experiment was to determine susceptibility of white-tailed deer to the agent of scrapie after intracerebral inoculation and to compare clinical signs and lesions to those reported for chronic wasting disease (CWD). Deer (n = 5) were inoculated with 1 mL of a 10% (wt/vol) brain homogenate derived from a sheep clinically affected with s ... | 2011 | 21988781 |
| Requirement for complement in antibody responses is not explained by the classic pathway activator IgM. | Animals lacking complement factors C1q, C2, C3, or C4 have severely impaired Ab responses, suggesting a major role for the classic pathway. The classic pathway is primarily initiated by antigen-Ab complexes. Therefore, its role for primary Ab responses seems paradoxical because only low amounts of specific Abs are present in naive animals. A possible explanation could be that the classic pathway is initiated by IgM from naive mice, binding with sufficient avidity to the antigen. To test this hyp ... | 2011 | 21987785 |
| Nitric oxide and angiotensin II regulate cardiovascular homeostasis and the arterial baroreflex control of heart rate in conscious lambs. | To investigate the potential role of angiotensin II (Ang II) type 1 receptors (AT(1)Rs) as well as endogenously produced nitric oxide (NO) in regulating cardiovascular homeostasis during ontogeny, experiments were carried out in conscious lambs aged approximately 1 week (N = 9) and 6 weeks (N = 11). The arterial baroreflex control of heart rate (HR) was assessed before and after intravenous (IV) infusion of the selective AT(1)R antagonist, ZD 7155, before and after IV administration of the L-arg ... | 2011 | 21987534 |
| evaluation of catharanthus roseus leaf extract-mediated biosynthesis of titanium dioxide nanoparticles against hippobosca maculata and bovicola ovis. | the purpose of the present study was based on assessments of the antiparasitic activities of synthesized titanium dioxide nanoparticles (tio(2) nps) utilizing leaf aqueous extract of catharanthus roseus against the adults of hematophagous fly, hippobosca maculata leach (diptera: hippoboscidae), and sheep-biting louse, bovicola ovis schrank (phthiraptera: trichodectidae). the synthesized tio(2) nps were analyzed by x-ray diffraction (xrd), fourier transform infrared spectroscopy (ftir), scanning ... | 2011 | 21987105 |
| differentiating ovine bse from ch1641 scrapie by serial protein misfolding cyclic amplification. | whilst ovine bse displays distinct pathological characteristics to ovine ch1641-like scrapie upon passage in rodents, they have very similar molecular phenotypes. as such, the in vitro differentiation of these strains in routine surveillance programmes presents a significant diagnostic challenge. in this study, using serial protein-misfolding cyclic amplification (spmca), ovine bse was readily amplified in vitro in brain substrates from sheep with v(136)r(154)q(171)/v(136)r(154)q(171) or ahq/ahq ... | 2011 | 21987099 |
| Using laser-induced breakdown spectroscopy to assess preservation quality of archaeological bones by measurement of calcium-to-fluorine ratios. | We determined calcium-to-fluorine (Ca/F) signal ratios at the surface and in the depth dimension in approximately 6000-year-old sheep and cattle bones using Ca I 671.8 and F I 685.6 emission lines. Because the bones had been previously analyzed for collagen preservation quality by measurement of C/N ratios at the Oxford Radiocarbon Accelerator Unit, we were able to examine the correlation between our ratios and quality of preservation. In the bones analyzed in this experiment, the Ca I 671.8/F I ... | 2011 | 21986080 |
| the importance of chill rate when characterising colour change of lamb meat during retail display. | an experiment was conducted to compare the effect of two chilling rates (con and fast) on colour change of lamb meat during simulated retail display. measurements were made on 3 muscles; ld (m. longisimuss dorsi), sm (m semimembranosus) and st (m. semitendinous). meat samples from 32 merino crossbred lambs were vacuum packed and stored for 5 days at 2 °c, then cut and overwrapped in polyvinyl chloride film on black polystyrene trays, stored in a display cabinet at 4 °c with lights on and measure ... | 2012 | 21985893 |
| purification of carbonic anhydrase-ii from sheep liver and inhibitory effects of some heavy metals on enzyme activity. | in this study; sheep carbonic anhydrase-ii (sca-ii) (e.c: 4.2.1.1) was purified from sheep liver and in vitro effects of heavy metals on the enzyme was examined. sca-ii isozyme was purified with about 203 purification fold, a specific activity of 2320 eu/mg-protein and a yield of 72 by using sepharose-4b-l tyrosine-sulfanilamide affinity gel chromatography. purity of the sca-ii enzyme was verified by sds-page technique and subunit molecular mass of the enzyme was found as 29 kda. in addition to ... | 2011 | 21985503 |
| medicinal animals used in ethnoveterinary practices of the 'cariri paraibano', ne brazil. | zootherapy is important in various socio-cultural environments, and innumerous examples of the use of animal derived remedies can currently be found in many urban, semi-urban and more remote localities in all parts of the world, particularly in developing countries. however, although a number of ethnobiological inventories concerning the use of medicinal animals in human health care have been compiled in brazil in recent years, zootherapeutic practices in ethnoveterinary medicine (evm) are poorl ... | 2011 | 21985401 |
| signal transducer and activation of transcription 6 (stat6) regulates t helper type 1 (th1) and th17 nephritogenic immunity in experimental crescentic glomerulonephritis. | experimental crescentic glomerulonephritis is driven by systemic cellular immune responses. a pathogenic role for t helper type 1 (th1) and th17 cells is well established. t-bet, a key transcription factor required for th1 lineage commitment, and retinoic acid-related orphan receptor-γt (rorγt), a key th17 transcription factor, are required for full expression of disease. similarly, several th1- and th17-associated cytokines have been implicated in disease augmentation. the role of th2 cells in ... | 2011 | 21985369 |
| interactions between mild nutrient imbalance and taste preferences in young ruminants. | thirty-two crossbred lambs (bw = 31.2 ± 4.7 kg; 16 females, 16 males) housed in individual pens were used to investigate the relationship between nutrient supply and taste preferences in ruminants. experiment 1, determined whether an imbalanced cp supply would alter preferences for feeds containing flavors designed to elicit either umami (u) or a mixture (⅓:⅓:⅓) of umami, sweet, and bitter (m) tastes. lambs were randomly allocated to either a low (lp; 10.9% cp) or a high (hp ... | 2011 | 21984714 |
| Congenital reflex myoclonus in two Merino cross lambs in South Africa. | 2011 | 21984564 | |
| Mastitis therapy and antimicrobial susceptibility: a multispecies review with a focus on antibiotic treatment of mastitis in dairy cattle. | Mastitis occurs in numerous species. Antimicrobial agents are used for treatment of infectious mastitis in dairy cattle, other livestock, companion animals, and humans. Mastitis is an economically important disease of dairy cattle and most mastitis research has focused on epidemiology and control of bovine mastitis. Antibiotic treatment of clinical and subclinical mastitis in dairy cattle is an established component of mastitis control programs. Research on the treatment of clinical and subclini ... | 2011 | 21984469 |
| In vivo response of bone defects filled with PMMA in an ovine model. | The use of PMMA cement is common in arthroplasty for cemented fixation and defect filling. Concerns remain regarding effects of cement curing temperature on the viability of cancellous bone. In this study we filled surgically-created defects (mean volume 0.585±0.251 mL) in the cancellous bone of the distal femur and proximal tibia of 6 sheep with PMMA and measured temperature changes in surrounding bone whilst the cement cured, using 3 thermocouples per defect. Animals were euthanised at 3 (n=3) ... | 2011 | 21983791 |
| The volatile compounds in lamb fat are affected by the time of grazing. | This study was designed to assess whether different grazing managements affect the appearance of organic volatile compounds (VOC) in lamb fat. Forty-two lambs were divided into four groups: 9 lambs were restricted in stall and fed concentrate (S group); 12 lambs grazed from 9 am to 5 pm (8h group); 10 lambs grazed from 9 am to 1 pm (4 hAM group) and 11 lambs grazed from 1 pm to 5 pm (4 hPM group). After 72 days on feed the animals were slaughtered and the perirenal fat subjected to SPME-GC/MS an ... | 2012 | 21983426 |
| Influence of alfalfa grazing-based feeding systems on carcass fat colour and meat quality of light lambs. | One hundred and twenty-seven lambs were fed as follows: lambs and dams grazing alfalfa (Gr); the same as Gr but lambs had access to concentrate (Gr + S); ewes grazed and lambs received milk and concentrate until weaning and thereafter concentrate and straw (Rat-Gr); ewes and lambs were stall-fed (Ind). Lambs were slaughtered at 22-24 kg live weight and fat and M. rectus abdominis colour was measured instrumentally and subjectively. The evolution of the instrumental colour and texture of M. longi ... | 2012 | 21983425 |
| variation in chst8 gene expression level affects prpc to prpsc conversion efficiency in prion-infected mov cells. | the conversion of the endogenous cellular prion protein to an abnormally folded isoform is a hallmark of transmissible spongiform encephalopathies. it occurs when a misfolded prion protein contacts the cellular prp. among the molecular partners suggested to be involved in the misfolding process, the glycosaminoglycans seem to be good candidates. the present study was aimed to examine a possible link between prp conversion efficiency and transcript level of chst8 gene that encodes the carbohydrat ... | 2011 | 21982770 |
| zoonotic dicrocoeliasis dendriticum in a farmer's family at giza governorate, egypt. | dicrocoeliasis (lancet liver fluke disease) is caused by dicrocoelium dendriticum, a trematode living in bile ducts of sheep, cattle and other mammals including man. human infection is asymptomatic or mild to moderately severe, but being sporadic or rarely reported. this paper reported zoonotic dicrocoeliasis dendriticum among a farmer's family and his domestic animals. the father and mother were successfully treated with triclabendazole and the children and animals were successfully treated wit ... | 2011 | 21980771 |
| discovery and genomic characterization of a novel ovine partetravirus and a new genotype of bovine partetravirus. | partetravirus is a recently described group of animal parvoviruses which include the human partetravirus, bovine partetravirus and porcine partetravirus (previously known as human parvovirus 4, bovine hokovirus and porcine hokovirus respectively). in this report, we describe the discovery and genomic characterization of partetraviruses in bovine and ovine samples from china. these partetraviruses were detected by pcr in 1.8% of bovine liver samples, 66.7% of ovine liver samples and 71.4% of ovin ... | 2011 | 21980506 |
| detectability counts when assessing populations for biodiversity targets. | efficient, practical and accurate estimates of population parameters are a necessary basis for effective conservation action to meet biodiversity targets. the brown hare is representative of many european farmland species: historically widespread and abundant but having undergone rapid declines as a result of agricultural intensification. as a priority species in the uk biodiversity action plan, it has national targets for population increase that are part of wider national environmental indicat ... | 2011 | 21980343 |
| Gastrointestinal nematode infections in German sheep. | The objective of the present study was to determine the prevalence and variation of natural gastrointestinal nematode (GIN) infections in lambs according to birth type, gender and breed based on individual faecal egg counts (FEC) from various regions in Germany. A total of 3,924 lambs (3 to 15 months old) with different genetic backgrounds (Merinoland, German Blackhead Mutton, Rhoen, Texel and Merino long-wool) were individually sampled during the grazing period between 2006 and 2008. Furthermor ... | 2011 | 21979784 |
| Efficacy of long-acting moxidectin against sarcoptic mange in naturally infested sheep. | 2011 | 21979442 | |
| Molecular characterization of peste des petits ruminants virus from the Karamoja region of Uganda (2007-2008). | Antibodies against peste des petits ruminants virus (PPRV) were first detected in goats in East Africa in 1995 without any clinical disease. It was not until during the years 2006 and 2007 that the disease outbreaks were first reported in Kenya and Uganda, respectively. This study was carried out to detect and characterize PPRV from a suspected outbreak in sheep and goats in the Karamoja region in 2007-2008. Oculo-nasal and blood samples were tested using F-gene-based primers, and their genetic ... | 2011 | 21979248 |
| Detection of polymorphism in AgB1 gene from sheep, cattle and human isolates of echinococcus granulosus by SSCP. | Antigen B (AgB) is a major protein produced by the metacestode cyst of Echinococcus granulosus, the causative agent of cystic hydatid disease. E. granulosus AgB is a gene family of at least five gene loci (B1-B5), each one consisting of several minor variants. We used PCR-SSCP followed by DNA sequencing to evaluate sequence variation and polymorphism of AgB1 in 99 isolates which the 43 were from cattle, 25 of sheep and 31 of human. All samples were analyzed with 12S rRNA-PCR for the strain detec ... | 2011 | 21978743 |
| Effect of production system on carcass measurements and meat quality of Kivircik lambs. | Effect of production system on carcass and meat quality was investigated in four groups of lambs: i. W-C lambs were weaned between 45 and 60 days of age and then were fattened with concentrate feed until slaughter; ii. W-G-S lambs were weaned and then taken to pasture and wheat stubble; iii. UW-C lambs were fattened with concentrate feed and they suckled their dams until slaughter; iv. UW-G lambs were kept with their dams and were taken to pasture in the day-time. Hot carcass weight was 13.62, 1 ... | 2012 | 21978412 |
| rift valley fever virus vaccine lacking the nss and nsm genes is safe, nonteratogenic, and confers protection from viremia, pyrexia, and abortion following challenge in adult and pregnant sheep. | rift valley fever virus (rvfv) is a mosquito-borne human and veterinary pathogen causing large outbreaks of severe disease throughout africa and the arabian peninsula. safe and effective vaccines are critically needed, especially those that can be used in a targeted one-health approach to prevent both livestock and human disease. we report here on the safety, immunogenicity, and efficacy of the δnss-δnsm recombinant rvfv (rrvfv) vaccine (which lacks the nss and nsm virulence factors) in a total ... | 2011 | 21976656 |
| x-linked inhibitor of apoptosis protein and active caspase-3 expression patterns in antral follicles in the sheep ovary. | x-linked inhibitor of apoptosis protein (xiap) interacts with caspases to inhibit their activity, thereby providing a potential mechanism for regulation of granulosa cell apoptosis occurring during follicular atresia. the aim of this study was to determine the presence and localization of xiap mrna and protein content in the sheep ovary and compare these expression patterns with active caspase-3 protein in the same antral follicles. romney ewe estrous cycles (n=25) were synchronized with 2-3 est ... | 2011 | 21976617 |
| Babesia ovis as the main causative agent of sheep babesiosis in Iran. | Babesiosis is a haemoparasitic disease with high economical losses in livestock industry worldwide. The early diagnosis and successful therapy of babesiosis belong to the key steps of control and health management of livestock. Ethanol-fixed blood samples of 400 sheep were analyzed for Babesia infection. Reverse line blot (RLB) was established specifically for Theileria lestoquardi, Theileria (China 1), Theileria (China 2), Theileria ovis, Theileria separata, Babesia ovis, Babesia motasi, Babesi ... | 2011 | 21975684 |
| geographical distribution of salmonella infected pig, cattle and sheep herds in sweden 1993-2010. | the swedish salmonella control programme covers the entire production chain, from feed to food. all salmonella serotypes are notifiable. on average, less than 20 cases of salmonella in food-producing animals are reported every year. in some situations, the cases would be expected to cluster geographically. the aim of this study was to illustrate the geographic distribution of the salmonella cases detected in pigs, cattle and sheep. | 2011 | 21975258 |
| Thyroid hormone drives fetal cardiomyocyte maturation. | Tri-iodo-l-thyronine (T(3)) suppresses the proliferation of near-term serum-stimulated fetal ovine cardiomyocytes in vitro. Thus, we hypothesized that T(3) is a major stimulant of cardiomyocyte maturation in vivo. We studied 3 groups of sheep fetuses on gestational days 125-130 (term ~145 d): a T(3)-infusion group, to mimic fetal term levels (plasma T(3) levels increased from ~0.1 to ~1.0 ng/ml; t(1/2)~24 h); a thyroidectomized group, to produce low thyroid hormone levels; and a vehicle-infusion ... | 2011 | 21974928 |
| Expression of keratin 19, Na-K-Cl cotransporter and estrogen receptor alpha in developing mammary glands of ewes. | Mammary gland remodelling is strictly related to intracellular signals and stem cell biology. Among the best candidates to identify the nature and development of mammary cells are cytokeratin 19 (CK19), the Na-K-Cl cotransporter (NKCC1) and receptor of estrogen alpha (ERa). In this study, we analyzed the expression of these genes in ewe mammary glands from prepubertal stage to involution. Using Real time PCR we showed that NKCC1 transcription was significantly down regulated during lactation and ... | 2011 | 21972095 |
| Three-year results from a preclinical implantation study of a long-term resorbable surgical mesh with time-dependent mechanical characteristics. | PURPOSE: The purpose of this study was to evaluate the biocompatibility, local tissue effects and performance of a synthetic long-term resorbable test mesh (TIGR(®) Matrix Surgical Mesh) compared to a non-resorbable polypropylene control mesh following implantation in a sheep model. METHODS: Full-thickness abdominal wall defects were created in 14 sheep and subsequently repaired using test or control meshes. Sacr ... | 2011 | 21972049 |
| Anti-inflammatory action of the Ovis aries lipidic fraction associated to therapeutic ultrasound in an experimental model of tendinitis in rats (Rattus norvegicus). | Studies have demonstrated the beneficial effects of topical application of fatty acids as healing agents. The lipid fraction of Ovis aries have an anti-inflammatory action that accelerates the healing process. Ultrasound increases blood flow and the extensibility of collagen structures and tendons. | 2011 | 21971725 |
| Role of tachykinin and neurokinin receptors in the regulation of ovine omasal contractions. | The present study investigated a role of tachykinins (TK) and neurokinin (NK) receptors (NK-R) in the non-cholinergic regulation of omasal contractions in sheep. Semiquantitative reverse transcription (RT)-PCR revealed that both preprotachykinin (PPT)-A and PPT-B mRNA were distributed in the omasal muscle layers and that NK-R type-1 (NK-1R) and type-2 (NK-2R) mRNA were largely expressed in the same tissues. Cumulative application of substance P (SP), neurokinin A (NKA), and neurokinin B (NKB) at ... | 2012 | 21971117 |
| the ratio of growth differentiation factor 9: bone morphogenetic protein 15 mrna expression is tightly co-regulated and differs between species over a wide range of ovulation rates. | recent evidence suggests that the species-specific ovulation-rate phenotypes may be influenced by differences in the expression levels of bone morphogenetic protein 15 (bmp15) and growth differentiation factor 9 (gdf9) mrna and protein. the aim of this study was to compare gdf9 and bmp15 mrna levels in individual denuded oocytes (do) from a range of single (i.e. cow, red deer), single-to-triple (i.e. sheep) and high (i.e. pig, mouse, rat) ovulation-rate species. compared to all other species stu ... | 2012 | 21970812 |
| influence of high-frequency cyclical stimulation on the bone fracture-healing process: mathematical and experimental models. | mechanical stimulation affects the evolution of healthy and fractured bone. however, the effect of applying cyclical mechanical stimuli on bone healing has not yet been fully clarified. the aim of the present study was to determine the influence of a high-frequency and low-magnitude cyclical displacement of the fractured fragments on the bone-healing process. this subject is studied experimentally and computationally for a sheep long bone. on the one hand, the mathematical computational study in ... | 2011 | 21969676 |
| functional adaptations of the transcriptome to mastitis-causing pathogens: the mammary gland and beyond. | application of microarrays to the study of intramammary infections in recent years has provided a wealth of fundamental information on the transcriptomics adaptation of tissue/cells to the disease. due to its heavy toll on productivity and health of the animal, in vivo and in vitro transcriptomics works involving different mastitis-causing pathogens have been conducted on the mammary gland, primarily on livestock species such as cow and sheep, with few studies in non-ruminants. however, the resp ... | 2011 | 21968536 |
| Genomic Diversity in Pig (Sus scrofa) and its Comparison with Human and other Livestock. | We have reviewed the current pig (Sus scrofa) genomic diversity within and between sites and compared them with human and other livestock. The current Porcine 60K single nucleotide polymorphism (SNP) panel has an average SNP distance in a range of 30 - 40 kb. Most of genetic variation was distributed within populations, and only a small proportion of them existed between populations. The average heterozygosity was lower in pig than in human and other livestock. Genetic inbreeding coefficient (F( ... | 2011 | 21966252 |
| Organic and inorganic selenium: I. Oral bioavailability in ewes. | Although the essentiality of dietary selenium (Se) for sheep has been known for decades, the chemical source and Se dosage for optimal health remain unclear. In the United States, the FDA regulates Se supplementation, regardless of the source of Se, at 0.3 mg Se/kg diet (as fed), which is equivalent to 0.7 mg Se/d or 4.9 mg Se/wk per sheep. The objectives of this study were to evaluate the effects of Se source (inorganic versus organic) and supplementation rate (FDA vs supranutritional rates of ... | 2011 | 21965451 |
| Organic and inorganic selenium: II. Transfer efficiency from ewes to lambs. | Adequate selenium (Se) transfer from ewes to lambs is important to prevent Se-deficiency diseases. To evaluate how different chemical forms of Se administered at comparative dosages to mature ewes affect Se status of their lambs, 240 ewes were divided into 8 treatment groups (n = 30 each) and drenched weekly (at an amount equal to their summed daily intake) with no Se (controls); at recommended levels (4.9 mg Se/wk) with inorganic Na-selenite, inorganic Na-selenate, or organic Se-yeast; or at su ... | 2011 | 21965446 |
| subtilase cytotoxin-coding genes in verotoxin-producing escherichia coli strains from sheep and goats differ from those from cattle. | subtilase cytotoxin (subab) from verotoxin (vt)-producing escherichia coli (vtec) strains was first described in the 98nk2 strain and has been associated with human disease. however, subab has recently been found in two vt-negative e. coli strains (ed 591 and ed 32). subab is encoded by two closely linked, cotranscribed genes (suba and subb). in this study, we investigated the presence of subab genes in 52 vtec strains isolated from cattle and 209 strains from small ruminants, using pcr. most (9 ... | 2011 | 21965402 |
| BSE: where are we now? | 2011 | 21965237 | |
| Losartan exerts no protective effects against acute pulmonary embolism-induced hemodynamic changes. | The acute obstruction of pulmonary vessels by venous thrombi is a critical condition named acute pulmonary embolism (APE). During massive APE, severe pulmonary hypertension may lead to death secondary to right heart failure and circulatory shock. APE-induced pulmonary hypertension is aggravated by active pulmonary vasoconstriction. While blocking the effects of some vasoconstrictors exerts beneficial effects, no previous study has examined whether angiotensin II receptor blockers protect against ... | 2011 | 21964667 |
| improved endothelialization and reduced thrombosis by coating a synthetic vascular graft with fibronectin and stem cell homing factor sdf-1α | failure of synthetic small-diameter vascular grafts is determined mainly by the lack of endothelial cells, as these cells inhibit thrombosis and intimal hyperplasia. coating of graft material with homing factors for circulating stem cells has the potential to improve endogenous endothelialization of these grafts and to reduce graft failure. synthetic knitted polyester grafts (6mm diameter) were coated with fn and sdf-1α before surgical interposition in the carotid artery of sheep. similar uncoat ... | 2011 | 21964214 |
| radio telemetry devices to monitor breathing in non-sedated animals. | radio telemetry equipment has significantly improved over the last 10-15 years and is increasingly being used in research for monitoring a variety of physiological parameters in non-sedated animals. the aim of this review is to provide an update on the current state of development of radio telemetry for recording respiration. our literature review found only rare reports of respiratory studies via radio telemetry. much of this article will hence report our experience with our custom-built radio ... | 2011 | 21964163 |
| development of a serodiagnostic test for sheep scab using recombinant protein pso o 2. | early stages of sheep scab, the disease caused by the non-burrowing mite psoroptes ovis, are often sub-clinical, or can be mis-diagnosed. a diagnostic test capable of detecting early disease and latent infestations is therefore highly desirable in disease control. this paper describes the design and validation of an elisa, which incorporates a recombinant p. ovis antigen (pso o 2), for the early detection of anti-p. ovis serum antibodies in sheep. this elisa was evaluated using sera from sheep i ... | 2011 | 21963943 |
| pyrosequencing analysis of the beta-tubulin gene in spanish teladorsagia circumcincta field isolates. | benzimidazole (bz) resistance in gastrointestinal nematodes has been associated with single nucleotide polymorphisms (snps) at codons 200, 167 and 198 in the beta-tubulin isotype 1 gene and, recently, these snps have also been found in macrocyclic lactone (ml) resistant strains of haemonchus contortus. on this basis, we have studied the same putative snps in spanish teladorsagia circumcincta field isolates by pyrosequencing. single l3 (infective 3rd stage larvae) from five sheep flocks were test ... | 2011 | 21962969 |
| use of mixed cultures of biocontrol agents to control sheep nematodes. | biological control is a promising non-chemical approach for the control of gastrointestinal nematodes of sheep. use of combinations of biocontrol agents have been reported to be an effective method to increase the efficacy of biological control effects. in this study, combinations of either two bacillus thuringiensis (bt) or clonostachys rosea (c. rosea) isolates and bt+c. rosea isolates were evaluated in vitro in microtitre plates for their biocontrol activity on sheep nematodes. the baermann t ... | 2011 | 21962967 |