Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
|---|
| therapeutic effect of the antiviral agent ribavirin in junín virus infection of primates. | in order to assess the effect of the antiviral ribavirin on the course of junín virus infection in callithrix jacchus, seven inoculated monkeys were treated with 15 mg of the drug, twice a day, starting 6 days after infection when all animals were viremic. the three untreated controls showed typical signs of junín virus infection at 14 days pi and their mean time of death was 18 days. in contrast, no signs of illness were detected in ribavirin-treated animals until 24 days pi, when marmosets sho ... | 1986 | 3023541 |
| herpesvirus saimiri strain 11 immortalizes a restricted marmoset t8 lymphocyte subpopulation in vitro. | herpesvirus saimiri induces a fatal lymphoproliferative syndrome in a variety of new world primate species. we now show that cell lines derived from pbl of the common marmoset by in vitro-immortalization with h. saimiri strain 11 represent a remarkably restricted lymphocyte population. these cell lines have nk cell function, phenotypically express both suppressor/cytotoxic (t8) and nk cell (nkh1)-associated antigens, and express a t cell receptor. this subpopulation of lymphocytes is a very mino ... | 1986 | 3018122 |
| the common marmoset as an animal model for vitamin d-dependent rickets, type ii. | 1986 | 3012983 | |
| establishment and characterization of a chronic infectious mononucleosislike syndrome in common marmosets. | epstein-barr virus (ebv) was inoculated into two species of marmosets. successful infection was established in the majority of the animals of one species, callithrix jacchus, as evidenced by the development of high, persistent levels of antibody against virus-specific capsid and early nonstructural proteins. antibodies also were produced against the major membrane antigen and, in some animals, against ebv nuclear antigen (ebna) 2 but not against ebna 1. this is the antibody profile normally note ... | 1986 | 3011982 |
| rapid diagnosis and management of parainfluenza i virus infection in common marmosets (callithrix jacchus). | during 1983 a severe episode of respiratory infection occurred in a marmoset colony at these laboratories. of 91 marmosets, 69 showed clinical signs of disease, one died and nine were so ill that euthanasia was necessary. eight were examined post mortem and all showed consolidation of the lungs. laboratory studies were carried out in an attempt to establish the cause of the outbreak and an interstitial pneumonia was found in seven animals which were examined histologically. direct electron micro ... | 1986 | 3009965 |
| ectrodactyly and syndactyly in a common marmoset (callithrix jacchus). | this paper describes previously unreported malformations of both fore and hind feet in a liveborn common marmoset. ectrodactyly of both fore feet and left hind foot and syndactyly of the right hind foot were observed. | 2010 | 3005763 |
| oral infection of a common marmoset with human t-cell leukemia virus type-i (htlv-i) by inoculating fresh human milk of htlv-i carrier mothers. | to obtain definitive evidence that milk-borne infection plays a critical role in the endemy or mother-to-child transmission of human t-cell leukemia virus type-i (htlv-i), we inoculated concentrated fresh human milk cells obtained from htlv-i carrier mothers into the oral cavity of a common marmoset (callithrix jacchus). twenty-eight milk samples were collected (5-10 ml each) from 17 carrier mothers in the first week after delivery. cells in the milk were centrifuged down and resuspended in 1/10 ... | 1985 | 3005206 |
| nononcogenic deletion mutants of herpesvirus saimiri are defective for in vitro immortalization. | herpesvirus saimiri l-dna sequences between 0.0 and 4.0 map units (4.5 kilobase pairs) are required for oncogenicity; these sequences are not required for replication of the virus. to investigate the basis for the lack of oncogenicity of mutants with deletions in this region and to study the function of this region, we developed a reliable system for in vitro immortalization by herpesvirus saimiri. in contrast to peripheral blood lymphocytes from cotton-top tamarins (saguinus oedipus) and owl mo ... | 1986 | 3003401 |
| palatability and digestibility of soya- and milk proteins in callithricidae. | 4 protein sources were tested for palatability, digestibility, influence on bodyweight and consistency of faeces in callithrix jacchus and saguinus fuscicollis. the protein sources were incorporated at crude protein levels of 12, 17 and 22% in a pelleted diet. a banana supplement was also fed which reduced the total protein content to 10.7, 14.7 and 18.3%. the test diets, fed for 3 weeks, were well accepted with the milk proteins being slightly preferred. consumption of the 12% protein pellets w ... | 1985 | 2993740 |
| oral transmission of human t-cell leukemia virus type-i into a common marmoset (callithrix jacchus) as an experimental model for milk-borne transmission. | to obtain experimental support for possible milk-borne infection of human t-cell leukemia virus type-i (htlv-i), short-term-cultured viral antigen-positive lymphocytes obtained from peripheral blood of adult t-cell leukemia lymphoma complex (atll) patients were inoculated into the oral cavity of two adult common marmosets (callithrix jacchus) in amounts comparable to those of htlv-i-carrying cells fed to a baby in the milk of seropositive mothers. one of the animals seroconverted 2.5 months afte ... | 1985 | 2991061 |
| the mechanism of end-organ resistance to 1 alpha,25-dihydroxycholecalciferol in the common marmoset. | the common marmoset, a new world monkey, requires a large amount of cholecalciferol (110 i.u./day per 100g body wt.) to maintain its normal growth. in a previous report, we demonstrated that the circulating levels of 1 alpha, 25-dihydroxycholecalciferol [1 alpha,25(oh)2d3] in the marmosets are much higher than those in rhesus monkeys and humans, but the marmosets are not hypercalcaemic [shinki, shiina, takahashi, tanioka, koizumi & suda (1983) biochem. biophys. res. commun. 14, 452-457]. to comp ... | 1985 | 2988503 |
| attenuated junin virus infection in callithrix jacchus. | twenty marmosets, male callithrix jacchus, were used during this study. fifteen of the marmosets were inoculated with 5,000 tcid50 of the attenuated xjc13 strain of junin virus by intramuscular route and five were left as uninoculated controls. animals were observed for a 420-day period. in order to carry out virologic, hematologic, serologic, and histologic studies the animals were bled and/or killed at different days post infection(pi). results obtained showed that the attenuated strain produc ... | 1985 | 2981980 |
| the d-1 dopamine receptor partial agonist, cy 208-243, exhibits antiparkinsonian activity in the mptp-treated marmoset. | administration of l-dopa plus carbidopa, or the d-2 agonist (+)-phno, to mptp-treated common marmosets caused motor hyperactivity and a reversal of the parkinsonian syndrome. in contrast, administration of the putative d-1 agonist skf 38393 was without effect on movement or motor disability. the subsequent administration of another putative selective d-1 partial agonist cy 208-243 produced a dose-related improvement in motor activity and reversal of parkinsonian motor deficits in mptp-treated an ... | 1988 | 2977118 |
| histochemical localization of 3 beta-hydroxysteroid dehydrogenase in marmoset ovaries during pro- and diestrus, with special reference to substrate specificity. | we applied qualitative cytochemical procedures to investigate and compare the distribution of 3 beta-hydroxysteroid dehydrogenases (hsdh) in pro- and diestrus ovaries of sexually mature marmosets (callithrix jacchus) using dehydroepiandrosterone or etiocholane-3 beta-ol-17-one as the substrate. during proestrus dehydroepiandrosterone dehydrogenase (3 beta-5 alpha-hsdh) activity was found in the theca of tertiary follicles and in atretic granulosa cells. in granulosa cells at advanced stages of d ... | 1987 | 2956223 |
| lymphocyte subsets in the young and aging marmoset (callithrix jacchus). | t lymphocytes were studied in healthy young and old marmosets (callithrix jacchus). data indicate that monoclonal antisera to human t lymphocyte antigens can be used to identify these cells in marmosets. total t and suppressor t cells were lower in the older group; there were no differences in helper t or in b cells. helper/suppressor ratios (t4/t8) were increased in the older group. thus, immune system alternations with aging and/or immune deficiency syndromes may be studied in this animal mode ... | 1986 | 2948018 |
| purification and properties of cytochrome p-450 from liver microsomes of phenobarbital-treated marmoset monkeys (callithrix jacchus). | one form of cytochrome p-450 from phenobarbital-induced marmoset liver was purified to apparent electrophoretic homogeneity and compared with the major inducible form isolated from rat liver. whereas spectral properties and molecular weights, as well as catalytic activities towards aminopyrine and ethylmorphine n-demethylation are quite similar, rates of o-dealkylation with enzymes from the two species are considerably different. while ethoxycoumarin deethylation for the marmoset cytochrome is a ... | 1989 | 2919406 |
| the d1 agonist skf 38393 inhibits the antiparkinsonian activity of the d2 agonist ly 171555 in the mptp-treated marmoset. | administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp) to common marmosets induced persistent motor deficits. administration of the d1 agonist skf 38393 (2.5-20 mg/kg, i.p.) caused a dose-dependent increase of this akinesia. administration of the d2 agonist ly 171555 (0.3 mg/kg, i.p.) reversed the motor deficits induced by mptp treatment. pretreatment of animals with skf 38393 (2.5-20 mg/kg, i.p.) caused dose-dependent inhibition of the anti-parkinsonian action of ly 171555 (0.3 m ... | 1988 | 2907373 |
| tissue activities of enzymes of diagnostic interest in the marmoset and rat. | the activities of enzymes of diagnostic interest were investigated in the liver, heart, kidney and muscle of the marmoset (callithrix jacchus) and the rat. methods of tissue extraction which gave maximal enzyme activity were used and comparison between the species showed some major differences. ast, ldh and gdh showed a similar distribution in both species but icdh activity was much higher in the rat heart than in any other rat or marmoset organ. alp, lap and ggt were present in much higher acti ... | 1988 | 2905366 |
| antiparkinsonian activity of (+)-phno in the mptp-treated common marmoset. | administration of mptp (1-4 mg/kg ip daily for 5-7 days) to common marmosets induced persistent parkinsonian motor deficits. the subcutaneous administration of (+)-phno [(+)-4-propyl-9-hydroxynaphthoxazine; 1-4 micrograms/kg] caused a dose-dependent reversal of the akinesia and incoordination of movement. similarly, oral administration of (+)-phno (5-20 micrograms/kg) caused an equivalent reversal of the motor abnormalities. no dyskinetic phenomena were induced by (+)-phno on oral or subcutaneou ... | 1987 | 2904119 |
| an immunohistochemical study of the acute and long-term effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in the marmoset. | administration of the drug 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine induces a parkinsonian syndrome in primates. intraperitoneal injections of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in the common marmoset (callithrix jacchus) produced symptoms of rigidity, akinesia and tremor which persisted for at least one month. however, after this time, considerable behavioural recovery occurred, although animals were still severely bradykinetic compared with controls. marmosets were allowed to sur ... | 1987 | 2893993 |
| behavioural consequences of the infusion of dopamine into the nucleus accumbens of the common marmoset (callithrix jacchus). | marmosets, shown to have comparable levels of spontaneous locomotor activity, assessed in cages equipped with infra-red photocell units, could be separated into "high", "moderate" and "low activity" responders on the basis of their locomotor hyperactivity response to peripherally administered (-)n-n-propylnorapomorphine [(-)npa]. animals selected as "low" and "high activity" responders to (-)npa were subjected to chronic infusion of dopamine, or its solvent, bilaterally into the nucleus accumben ... | 1987 | 2890118 |
| mptp-induced parkinsonism in the common marmoset: behavioral and biochemical effects. | 1987 | 2881443 | |
| thermogenic capacity and brown adipose tissue activity in the common marmoset. | resting oxygen consumption was measured in anaesthetized male and female common marmosets (callithrix jacchus) at 29 degrees c. injection of noradrenaline caused a marked increase in oxygen consumption (63%), but this response was lower in males. large deposits (750 mg) of brown adipose tissue (bat) were dissected from the cervical, subscapular, axillary and perirenal areas. high levels of guanosine diphosphate binding to isolated brown fat mitochondria were observed, indicating that the thermog ... | 1985 | 2863059 |
| [cytochemical studies of hydrolases in the genitalia of female marmosets (callithrix jacchus) and rats]. | 1985 | 2862661 | |
| glomerulonephritis in common marmosets infected with plasmodium brasilianum and epstein-barr virus. | plasmodium brasilianum causes chronic quartan malaria in the common marmoset callithrix jacchus, whereas epstein-barr virus (ebv) infection is followed by an infectious mononucleosis-like syndrome that resolves. we infected weanling marmosets with one or both of these pathogens. timing of the infections influenced outcome. six animals were simultaneously infected with both agents; four became seriously ill (with accompanying proteinuria and edema) and either died or were killed. histopathology i ... | 1988 | 2844917 |
| expression of c-type viral particles at implantation in the marmoset monkey. | type c rna retroviral particles have been observed budding from the plasma membrane of syncytiotrophoblast during a study of embryo implantation in the common marmoset (callithrix jacchus). these viral particles appear in profusion at the interface of syncytiotrophoblast with cytotrophoblast. they appear to be a non-infective, endogenous viral component of the host genome, although the precise role of the c-type virus in this context is unclear at present. such viral particles have been reported ... | 1988 | 2836475 |
| long-term protection against argentine hemorrhagic fever in tacaribe virus infected marmosets: virologic and histopathologic findings. | tacaribe virus may represent a better alternative than attenuated strains of junin virus (jv) for immunization against argentine hemorrhagic fever (ahf) because of possible risk of persistent infection of disease associated with live, attenuated strains. callithrix jacchus marmosets, which suffer 100% mortality if inoculated with the pathogenic xj strain of jv, were used to evaluate possible tacaribe virus persistence, subclinical, or long-term disease and the duration of protection against chal ... | 1988 | 2832541 |
| herpesvirus ateles immortalizes in vitro a cd3+cd4+cd8+ marmoset lymphocyte with nk function. | herpesvirus ateles, nonpathogenic in its natural host, the spider monkey, induces a fatal lymphoproliferative syndrome in a variety of new world primate species. whereas the closely related new world primate virus herpesvirus saimiri immortalizes in vitro common marmoset lymphocytes that express a tcr and phenotypically are cd4-cd8+nkh1+, we now show that h. ateles-immortalized marmoset lymphocytes are cd3+ and cd4+. furthermore, these cd4+ lymphocytes coexpress cd8 and nkh1. the nk function of ... | 1988 | 2828471 |
| in vitro immortalization of marmoset cells with three subgroups of herpesvirus saimiri. | sequences within the rightmost 7 kilobases of the unique l dna of herpesvirus saimiri are required for oncogenicity of the virus. the same dna region has been found to be highly variable among different strains of herpesvirus saimiri. on the basis of this variability, herpesvirus saimiri strains were classified into groups a, b, and non-a, non-b. herpesvirus saimiri strains representing the three groups were used successfully for in vitro immortalization of phytohemagglutinin-activated, interleu ... | 1987 | 2822956 |
| naloxone reversal of stress-induced suppression of lh release in the common marmoset. | there is considerable evidence suggesting that endogenous opioid peptides (eop) might play a role in the defensive response to stressful stimuli. the stress associated with receipt of aggression from a female conspecific and physical restraint for collection of serial blood samples (at 10-min intervals) resulted in a significant (p less than 0.05) suppression of lh secretion in the oestradiol primed ovariectomized marmoset. administration of the opioid receptor antagonist, naloxone (1 mg/kg) imm ... | 1989 | 2780870 |
| immunohistochemical distribution and colocalization of regulatory peptides in the carotid body. | current investigations on the immunohistochemical occurrence and co-occurrence of biogenic polypeptides in the mammalian carotid body were reviewed and extended by our own recent findings. the family of chromogranins and related peptides in glomus cells appears to have a widespread interspecies distribution, whereas other peptides investigated occur in a species-specific pattern. immunoreactivity to antisera against opioids, which derive from the proenkephalin sequence, appears to be present in ... | 1989 | 2671303 |
| in vivo formation of metabolites of prostaglandins i2 and i3 in the marmoset monkey (callithrix jacchus) following dietary supplementation with tuna fish oil. | recent studies have shown that ingestion of eicosapentaenoic acid (epa) in man results in the formation of 'trienoic' prostanoids which amy partly explain the potent antithrombotic/antiatherogenic properties of long-chain polyunsaturated n-3 fatty acids (pufas). however, endogenous formation of cyclooxygenase metabolites of epa has not been demonstrated in an animal model, and in vitro studies indicate a clear species difference in the conversion of epa to pgi3. thus, in the present study, the i ... | 1989 | 2659082 |
| transient depletion of nucleus accumbens dopamine content may contribute to initial akinesia induced by mptp in common marmosets. | acute treatment of common marmosets with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp) caused an initial profound akinesia and other motor deficits. however, over the following months akinesia gradually disappeared although the animals remained clumsy and poorly coordinated. at 10 days following mptp treatment there was a profound decrease in the dopamine, hva and dopac content of the caudate nucleus, putamen and nucleus accumbens. by 3-4 months following mptp treatment the animals had lar ... | 1989 | 2597167 |
| desenkephalin-gamma-endorphin is an antagonist of the hyperactivity response induced by infusion of dopamine into the nucleus accumbens of rat and ventral striatum of marmoset. | the ability of desenkephalin-gamma-endorphin (de gamma e; org5878) to antagonise a raised limbic dopamine function was investigated in the rat and common marmoset. dopamine was infused for 13 days directly into the nucleus accumbens of the rat and ventral striatum of the marmoset and increased locomotor activity. such increases in both the rat and marmoset were antagonised by the subcutaneous injection of de gamma e, administered in a range 10-500 micrograms/kg (t.i.d.), during the 13 day period ... | 1989 | 2574424 |
| stereoselective reversal of mptp-induced parkinsonism in the marmoset after dermal application of n-0437. | the selective dopamine d-2 receptor agonist n-0437 produced a rapid and dose-dependent reversal of motor deficits lasting 90-120 min following i.p. or oral administration of the racemate to mptp-treated common marmosets. in contrast, topical application of (+/-)-, (+)- or (-)-n-0437 to the skin of mptp-treated animals did not alter locomotor activity in the initial 4 h although other motor disabilities were reduced. however, 24 h following application of the racemate or the (-) enantiomer both l ... | 1989 | 2572426 |
| the histochemical location of three diagnostic enzymes in the marmoset liver. | the histochemical locations of alkaline phosphate (alp), leucine aminopeptidase (lap) and gamma glutamyltransferase (ggt) were demonstrated in the liver of the marmoset (callithrix jacchus). although all three enzymes were located in cell membranes, the location of lap was demonstrated by a chromogenic substrate, in the canalicular membrane. ggt was seen in a vascular network, provisionally identified as the peribiliary arterial plexus. possible diagnostic applications in toxicology are discusse ... | 2008 | 2565922 |
| tissue specific differences in the fatty acid composition of the marmoset monkey (callithrix jacchus). | 1. the possible relationship between the fatty acid composition of the adipose tissue of the marmoset monkey (callithrix jacchus) and its dietary lipid intake was examined after a long-term feeding trial. 2. only the proportions of stearic and linoleic acid in the adipose tissue were similar to those in the diet. the proportions of all other saturated and unsaturated fatty acid components were significantly different thus greatly reducing the potential value of this relationship in the marmoset. ... | 1989 | 2565781 |
| the callimico goeldii (primates, platyrrhini) genome: karyology and middle repetitive (line-1) dna sequences. | callimico goeldii (goeldi's marmoset) is a neotropical primate with 2n = 47,x1x2y in the male, and 2n = 48,x1x1x2x2 in the female, due to a y-autosome translocation. karyological comparisons of callimico, callithrix jacchus and cebus apella suggest that callimico is a member of the callitrichidae. isozyme data and restriction mapping of line-1 repetitive elements in these species and in a variety of other neotropical primates confirm these findings and supply strong evidence for including callim ... | 1989 | 2560695 |
| changing responsiveness of luteal cells of the marmoset monkey (callithrix jacchus) to luteotrophic and luteolytic agents during normal and conception cycles. | dispersed marmoset luteal cells were incubated for 2 h and progesterone production measured after exposure to hcg, cloprostenol, dibutyryl camp, pgf-2 alpha, pgf-2, adrenaline or melatonin. the cells were studied on days 6, 14 and 20 after ovulation in conception and non-conception cycles. luteal cells from day 14 non-pregnant marmosets were compared with human luteal cells taken in the mid-luteal phase. all the treatments stimulated progesterone production including cloprostenol, which is luteo ... | 1989 | 2560061 |
| blockade of the oestrogen-induced lh surge in the ovariectomized common marmoset (callithrix jacchus) by an lhrh antagonist. | six long-term ovariectomized adult marmoset monkeys were treated at 0 h with 35 micrograms oestradiol benzoate s.c. to induce an lh surge. they were also treated with detirelix (an lhrh antagonist) at 0 h, 12 h and 24 h (exp. 1), or at 0 h and 24 h (exp. 2) at a dose of 300 micrograms/kg s.c., or received the detirelix vehicle alone at 0 h, 12 h and 24 h (exp. 3). all animals received the three treatments, with at least 4 weeks between experiments. blood samples were collected at 0 h and at 6-12 ... | 1989 | 2539474 |
| milk-borne transmission of htlv-i as a major route in the endemic cycle. | mother-to-child transmission of htlv-i as a major route in the endemic cycle of htlv-i was established by epidemiologic evidence that (1) 22% (17/78) of children of htlv-i carrier mothers were themselves carriers, in contrast to approximately 1% of the young age population of the same area, (2) more than 95% (23/24) of mothers of carrier children were themselves carriers, and (3) the product of the prevalence of carrier mothers and the incidence of carriers in children born to them corresponded ... | 1989 | 2514566 |
| splitting of the circadian activity rhythm in common marmosets (callithrix j. jacchus; primates). | long-term recordings of the free-running circadian activity rhythm in common marmosets, callithrix j. jacchus, living under constant environmental conditions (ll 200-470 lx) provided evidence of rhythm splitting in nonhuman primates. in two out of ten test animals two different types of splitting occurred; spontaneous persistent splitting and temporary splitting. neither a reduction of the illumination intensity nor the application of dark pulses had any effect on the two activity components of ... | 1989 | 2513221 |
| treatment with a selective mao b inhibitor prevents loss of dopamine in the nucleus accumbens of mptp-treated common marmosets. | administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp) to common marmosets induced motor deficits, associated with a marked decrease in the uptake of [3h]dopamine into synaptosomes in the putamen and a reduction in the content of dopamine in both caudate nucleus and nucleus accumbens. histological analysis showed a marked loss of dopamine-containing cells in the zona compacta of the substantia nigra and less loss in the ventral tegmental area. treatment of animals with the selecti ... | 1989 | 2512516 |
| [mother to child transmission of human t cell leukemia virus type-1]. | infection of htlv-1 during childhood may be the most probable cause of leukemogenesis of atl. the possibility of mother to child transmission of htlv-1 was studied. our epidemiological investigation disclosed that almost all mothers of htlv-1 carrier children were positive for anti-htlv-1 antibody and children born from carrier mothers showed statistically higher positive rate for anti-htlv-1 antibody than control groups. a large number of htlv-1 positive lymphocytes were detected in the milk fr ... | 1989 | 2512396 |
| learning about rules but not about reward is impaired following lesions of the cholinergic projection to the hippocampus. | common marmosets with bilateral ibotenic acid-induced destruction of the neurones of the vertical limb of the diagonal band of broca, which provide the major cholinergic input to the hippocampal formation, were impaired on the acquisition but not on the retention of a repeated-trial visuospatial discrimination learning task. they were also impaired on serial spatial reversal learning (but not on serial object reversal learning), on acquisition of a trial-independent successive concurrent discrim ... | 1989 | 2510907 |
| further treatment with mptp does not produce parkinsonism in marmosets showing behavioural recovery from motor deficits induced by an earlier exposure to the toxin. | 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp), or 0.9% saline, was administered to a group of common marmosets initially treated with the toxin 12-18 months previously. initial treatment had consisted of a cumulative dose of 6-22 mg/kg (i.p.) which caused marked parkinsonism. subsequently, the animals gradually recovered normal motor function. further treatment consisted of a cumulative dose of mptp of 78-83 mg/kg (i.p.) but this produced only modest akinesia. at 12-18 months after the ini ... | 1989 | 2510050 |
| systems for collection of urine in the captive common marmoset, callithrix jacchus. | two systems are described for the collection of 24 h urine samples from the common marmoset (callithrix jacchus). using 84 adult animals, 1210 24-h samples were collected. mean urinary excretion was 14.4 +/- 7.5 ml/24 h (n = 1210, mean +/- sd). no differences were observed between sexes (for 52 females, 24 h volume = 15.1 +/- 8.0 ml; for 32 males, 24 h volume = 12.5 +/- 6.0 ml). no significant differences were observed between pregnant and non-pregnant females with respect to 24 h urine volume, ... | 1989 | 2509801 |
| control of inhibin production by primate granulosa cells. | in-vitro data from experiments on rats implicate granulosa cells as primary sites of hormone-dependent ovarian inhibin biosynthesis, but no equivalent data exist for primates. we have used the common marmoset (callithrix jacchus) to investigate inhibin biosynthesis in primate granulosa cells in vitro and to determine its relationship to preovulatory follicular development. to relate the production of immunoactive inhibin to follicular maturity, we studied primary granulosa cell cultures from fol ... | 1989 | 2509620 |
| a new transmissible viral hepatitis of marmosets and tamarins. | callitrichid hepatitis (ch) is a newly recognized, acute, fatal, epizootic disease of new world primates in the family callitrichidae. since 1980, 12 outbreaks of ch have occurred in us zoos, involving several callitrichid species including the endangered golden lion tamarin (leontopithecus rosalia). ch was experimentally transmitted to common marmosets via a bacteria-free filtrate of liver from a naturally infected tamarin. all three inoculated marmosets developed an acute fatal disease with th ... | 1989 | 2509570 |
| fall in coronary heart disease mortality in u.s.a. and australia due to sudden death: evidence for the role of polyunsaturated fat. | epidemiological studies have been reviewed which provide suggestive evidence of an association between the fall in coronary heart disease mortality in the u.s.a and australia since 1967, characterized by a fall in sudden deaths, to the increase in polyunsaturate fat consumption that has occurred in both countries since 1960. this association led directly in the same institution to carefully designed experimental studies undertaken in the rat, and a non-human primate, the marmoset (callithrix jac ... | 1989 | 2506314 |
| shortening of luteal phase in common marmosets by sheep ovarian follicular fluid peptide. | a low molecular weight peptide has been partially purified from sheep follicular fluid. it inhibited fsh binding to granulosa cells from ovarian follicles of common marmosets (callithrix jacchus). when injected into cycling marmosets during the follicular phase, it reduced the area under the curve (auc) of circulating progesterone. the peptide also shortened the luteal phase in all marmosets during the treatment cycle compared to the pretreatment control cycle. these results indicate that the ov ... | 1989 | 2505972 |
| luteal deficiency caused by human ovarian follicular fluid peptide in post-partum marmosets, callithrix jacchus. | a peptide purified from human ovarian follicular fluid (hoffp) was administered during the follicular phase of post-partum marmosets. four of the five animals treated with hoffp, ovulated as evidenced by the presence of ovarian stigmata at the time of laparotomy. however, only 2 of these animals became pregnant, one had a normal delivery while the other aborted. a shortening of the luteal phase was observed in the other three animals and all animals conceived in subsequent cycles. the results in ... | 1989 | 2505968 |
| [ultrastructure of the gastrointestinal epithelium in the marmoset (callithrix jacchus)]. | the epithelium of the stomach and intestine of one and three days old as well as adult marmosets was investigated using transmission electron microscopy and was compared with already existing data of man and the laboratory rodents, rat, mouse and guinea-pig. on postnatal day (pd) 1, the enterocytes possessed an inframicrovillous membrane system and giant lysosomes which were absent in adult marmosets whereas the surface and glandular epithelial cells of the stomach showed all structures which we ... | 1989 | 2505460 |
| increased caudate dopamine turnover may contribute to the recovery of motor function in marmosets treated with the dopaminergic neurotoxin mptp. | administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp) to common marmosets initially impaired motor function, but a partial recovery occurred over the following weeks. at both 10 days and 4-6 weeks following mptp treatment, [3h]dopamine ([3h]da) uptake into synaptosomal preparations of putamen was markedly decreased. at 10 days and 4-6 weeks following mptp treatment da, homovanillic acid (hva) and 3,4-dihydroxyphenylacetic acid (dopac) levels in the caudate nucleus and nucleus acc ... | 1989 | 2505199 |
| the protein requirement of adult marmosets: nitrogen balances and net protein utilization of milk proteins, soy protein, and amino acid mixtures. | nitrogen balance studies were conducted in adult male marmosets (callithrix jacchus) using purified and semipurified diets with protein levels between 0% and 7%. daily nitrogen loss in a state of prolonged protein free nutrition was 131 +/- 16 mg/kg body weight0.75. zero nitrogen balance resulted from mean daily intake of 261 mg nitrogen/kg0.75 when high quality protein sources were used. very low protein intake or the lack of arginine and histidine in an amino acid mixture induced coprophagy. i ... | 1989 | 2503946 |
| a re-investigation of the behavioural effects of intracerebral injection in marmosets of cytopathic cerebrospinal fluid from patients with schizophrenia or neurological disease. | in experiments designed to investigate transmission, cerebrospinal fluid (csf) from patients with schizophrenia or neurological disease (huntington's disease) which had been found to induce a cytopathic effect (cpe) in human embryonic fibroblast cell culture was injected intracerebrally into common marmosets. behavioural observations were made on the animals during a period of 2 1/2 years prior to injection and for 2 1/2 years after injection. in an earlier study (baker et al. 1983 b) we found t ... | 1989 | 2503849 |
| inoculation of new world primates with the human immunodeficiency virus. | the susceptibility of common marmosets and cotton-top tamarins to infection by hiv-2 in vivo was tested. one year and 19 months, respectively, post-inoculation, sera taken from three of four animals from each species are reactive for hiv-2 antibodies and hiv-specific nucleotide sequences were demonstrated in short-term cultures of pbl from two cotton-top tamarins. the animals remain in good health. | 1989 | 2503618 |
| termination of pregnancy in common marmosets (callithrix jacchus) following administration of antiserum to chicken riboflavin carrier protein. | the presence of protein(s) which is immunologically and functionally similar to the well characterised avian riboflavin carrier protein has been demonstrated in female common marmosets during pregnancy. the protein(s) that interacts with [14c]riboflavin has an immunological homology to chicken riboflavin carrier protein. the termination of pregnancy in four out of six marmosets following administration of antiserum to chicken riboflavin carrier protein supports the hypothesis that vitamin carrie ... | 1989 | 2503615 |
| distribution of phenolsulphotransferase and monoamine oxidase in the common marmoset. | 1989 | 2502120 | |
| progesterone antagonist lilopristone: a potent abortifacient in the common marmoset. | the effects of a progesterone antagonist zk 98.734 (lilopristone) on implantation, early pregnancy, and midpregnancy were studied in the common marmoset, callithrix jacchus jacchus. treatment (5 mg/da intramuscularly for 3 consecutive days) on day (n = 8) after the midcycle peak in estradiol levels in mated animals induced a premature drop in plasma progesterone levels and shortened the ovarian cycle length. treatment on day 20 (n = 5) or day 40 (n = 5) induced a drop in progesterone levels and ... | 1989 | 2502015 |
| description of eight phases of spermiogenesis in the marmoset testis. | the differentiation of spermatids in the marmoset (callithrix jacchus, n = 9) testis is described here at the light-microscopic level employing serial semithin sections. the definition of 8 different phases of spermiogenesis, i.e. the formation of spermatids, is based upon the changes in the development of nucleus, acrosome and flagellum. | 1989 | 2501964 |
| effects of male partners upon proceptivity in ovariectomized estradiol-treated marmosets (callithrix jacchus). | effects of male partners upon the expression of female proceptivity were examined in two experiments using 16 ovariectomized marmosets. experiment 1 showed that the female's proceptive tongue-flicking display (ptf) is triggered specifically by eye contact with the male. stimulation of ptf by administration of estradiol-17 beta (e2) to ovariectomized females depends in part upon the male's responsiveness to female displays, such as "staring" and "freezing," which may serve to attract his attentio ... | 1989 | 2501211 |
| experimental brugia pahangi and b. malayi infections of callitrichid primates. | the callitrichid primates, callithrix jacchus jacchus (the marmoset) and saguinus labiatus (the tamarin) were inoculated with infective larvae of brugia malayi and b. pahangi. microfilaraemia at low levels developed in 3 out of 4 c.j. jacchus infected with b. malayi and living or dead adult worms found in all 4. only one of 4 c.j. jacchus became microfilaraemic (mf + ve) when given b. pahangi and adults were found in two. of 4 s. labiatus given b. pahangi one became very lightly mf + ve and adul ... | 1989 | 2500478 |
| comparative studies on nafenopin-induced hepatic peroxisome proliferation in the rat, syrian hamster, guinea pig, and marmoset. | nafenopin was administered orally for 21 days to male sprague-dawley rats (0.5-50 mg/kg/day), syrian hamsters (5-250 mg/kg/day), dunkin-hartley guinea pigs (50 and 250 mg/kg/day), and marmosets (callithrix jacchus, 50 and 250 mg/kg/day). with the rat, and to a lesser extent in the hamster, nafenopin treatment produced dose-related increases in liver size and induction of peroxisomal (palmitoyl-coa oxidation) and microsomal (lauric acid 12-hydroxylase) fatty acid oxidizing enzyme activities. in c ... | 1989 | 2499080 |
| heinz bodies do not modify the membrane characteristics of common marmoset (callithrix jacchus) erythrocytes. | the possibility was examined that the membrane function of erythrocytes obtained from healthy common marmosets (callithrix jacchus) was modified by the presence in the cells of heinz bodies. no significant differences were found in erythrocyte endogenous free malonyl dialdehyde (mda) or reduced glutathione (gsh) between normal human erythrocytes and marmoset erythrocytes containing heinz bodies. membrane fluorescent chromolipids, surface charge and thiol levels were similar in both species but a ... | 1989 | 2498578 |
| ascorbic acid in a new world monkey family: species difference and influence of stressors on ascorbic acid metabolism. | like other simian primates, the new world monkey callithrix jacchus, marmoset, and saguinus fuscicollis, tamarin, require ascorbic acid as an essential nutrient. for adult marmosets, a daily intake of 15 mg/kg metabolic body weight was found to be necessary to obtain a serum level above the kidney threshold. a survey of the serum ascorbic acid level of marmosets and tamarins in a breeding colony resulted in a vast divergence between the two species, indicating a higher ascorbic acid requirement ... | 1989 | 2497592 |
| the distribution of glial fibrillary acidic protein and vimentin in postnatal marmoset (callithrix jacchus) brain. | antisera to glial fibrillary acidic protein (gfap) and vimentin were used to elucidate the distribution of these intermediate filament proteins in postnatal marmoset brains of various ages. the ependyma of the lateral ventricles was unique in being equally immunoreactive for both gfap and vimentin at all ages. vimentin alone was consistently demonstrated in endothelial and leptomeningeal cells at all ages. in neonates, vimentin immunoreactivity greatly exceeded that of gfap and was located prima ... | 2008 | 2496940 |
| the evolution and distribution of morphological changes in the nervous system of the common marmoset following the acute administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. | six young adult marmosets received 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in multiple doses (total 8-16 mg/kg over 2-13 days) sufficient to produce a parkinsonian syndrome and were killed up to 3.5 months later. cellular changes were found in the substantia nigra, ventral tegmental area, and hypothalamus. the earliest histological abnormalities were axonal swellings in proximal parts of nigrostriatal axons. subsequent changes in the substantia nigra were reduced nissl staining, reduced cel ... | 1989 | 2494438 |
| the diagnostic usefulness of isocitrate dehydrogenase (icdh) in the marmoset (callithrix jacchus). | marmosets were given either a hepatotoxin, carbon tetrachloride, orally or an i.m. injection of a mytoxin, chlorpromazine. although muscle damage alone caused small increases in the plasma levels of lactate dehydrogenase, alanine aminotransferase, aspartate aminotransferase and isocitrate dehydrogenase (icdh), only the isoenzyme analysis of icdh can differentiate definitely between liver and muscle damage. only very severe muscle damage can increase the plasma concentration of this enzyme but, i ... | 1989 | 2494250 |
| developmental changes in luteinizing hormone/human chorionic gonadotropin steroidogenic responsiveness in marmoset granulosa cells: effects of follicle-stimulating hormone and androgens. | factors regulating lh/hcg responsiveness in primate granulosa cells were examined in the marmoset monkey (callithrix jacchus). granulosa cells were isolated and pooled from small antral (0.5-1.0 mm) and large preovulatory (greater than or equal to 2 mm) follicles from mid- to late follicular phase ovaries of cyclic marmosets. the cells from small and large follicles were cultured in serum-free medium for 48 h in the absence or presence of increasing concentrations of hcg (0.1-100 ng/ml) with or ... | 1989 | 2494036 |
| comparison of the metabolism and disposition of [3-14c]coumarin in the rat and marmoset (callithrix jacchus). | male sprague-dawley rats and marmosets were given a single oral 25 mg/kg dose of [3-14c]coumarin and the excretion of radioactivity in the expired air, urine and faeces monitored up to 96 h. excretion profiles were similar in both species with the bulk of the dose being excreted in the urine and faeces within 24 h. chromatographic analysis of 0-48 h urine samples revealed similar metabolic profiles with only small amounts of unchanged coumarin and very little 7-hydroxycoumarin. coumarin 7-hydrox ... | 1989 | 2493171 |
| connective tissue of the livers of newborn and adult marmosets (callithrix jacchus). | immunofluorescence microscopic and electron microscopic investigations revealed components of the matrix and of the basal lamina (collagen type i, iii, iv and v, bl-heparan sulfate and fibronectin) in the sinus wall (disse's space) of the livers of newborn and adult marmosets (callithrix jacchus). collagen type i was missing in both the two age groups. small amounts of laminin were present in the livers of newborn and absent in those of adult animals, whereas collagen type iii occurred in the fo ... | 1989 | 2485198 |
| differences in transneuronal transport of horseradish peroxidase conjugated wheat germ agglutinin in the visual system: marmoset monkey and guinea pig compared. | conjugates of the lectin wheat germ agglutinin with horseradish peroxidase have been described as effective transneuronal tracers in different neuronal systems of various mammalian species. here, the failure is described to detect any sign of transneuronal transport of the tracer in the visual system of adult marmoset monkeys (callithrix jacchus), in spite of heavy anterograde labeling in the primary visual centers after intravitreous injections. in contrast, in the brains of guinea pigs process ... | 1989 | 2473107 |
| loss of ocular dominance columns with maturity in the monkey, callithrix jacchus. | previous studies have shown that adult marmosets lack ocular dominance columns (odc) in area 17, but that odcs can be demonstrated upon visual deprivation. the present results, obtained by transneuronal transport of wga-hrp, indicate that odcs normally develop in juvenile marmosets but disappear before the animal reaches maturity. the findings suggest that formation of odcs during ontogenesis, and their persistence through adulthood, are different developmental processes depending on different m ... | 1989 | 2472851 |
| levels of met-enkephalin, leu-enkephalin, substance p and cholecystokinin in the brain of the common marmoset following long term 1-methyl-4-phenyl-1,2,3,6,-tetrahydropyridine treatment. | common marmosets were treated daily with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp, 7-9 mg/kg i.p.) for 25 days, and then kept out of drug for three months before biochemical measurements in various brain areas. this treatment induced a dramatic fall (-80%) in dopamine, homovanillic acid and dihydroxyphenylacetic acid levels in the putamen and caudate nucleus, and a significant but less pronounced reduction (less than or equal to 50%) in the levels of these compounds in the nucleus accu ... | 1988 | 2468106 |
| persistence of the pars externa system of the anterior olfactory nucleus in a microsmatic primate, callithrix jacchus. | the pars externa (pe) system of the anterior olfactory nucleus (aon) in a primate, callithrix jacchus, was defined by its architecture and by its connection patterns with the main olfactory bulb (mob) as revealed by tracing techniques. focal, unilateral injections of wheat germ agglutinin-conjugated horseradish peroxidase into the mob yielded ipsilaterally labelled afferent neurons in all subdivisions of the aon, with the exception of a clearly circumscribed area in the ventrolateral retrobulbar ... | 1988 | 2458800 |
| distribution and some projections of cholinergic neurons in the brain of the common marmoset, callithrix jacchus. | the distribution of choline acetyltransferase-immunoreactive (chat-ir) neurons was studied in the brain of the common marmoset by using immunohistochemistry. chat-ir neurons were found in the medial septal nucleus, vertical and horizontal limb nuclei of the diagonal band, the nucleus basalis of meynert, pedunculopontine nucleus and laterodorsal tegmental nucleus, and also in the striatum, habenula, and brainstem cranial nerve motor nuclei. the organization of chat-ir neurons in the basal forebra ... | 1988 | 2454972 |
| dietary lipid modulation of myocardial beta-adrenergic mechanisms, ca2+-dependent automaticity, and arrhythmogenesis in the marmoset. | dietary lipid supplements high in either saturated fatty acids derived from sheep perirenal fat or polyunsaturated fatty acids (65% linoleic acid) derived from sunflower seed oil were fed to marmoset monkeys (callithrix jacchus) for 20 months. the effect of these long-term dietary lipid supplements on myocardial contractile function and their influence on responses to isoprenaline and external calcium concentration were examined using isolated papillary muscles and atria. isoprenaline potency wa ... | 1987 | 2444777 |
| lack of change in basal ganglia neuropeptide content following subacute 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine treatment of the common marmoset. | treatment of common marmosets with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp; 1-4 mg/kg for up to 4 days) caused a profound parkinsonian state. ten days from the start of mptp treatment, all animals showed marked motor impairment, consisting of bradykinesia and akinesia, limb rigidity, postural abnormalities, loss of vocalisation and blink reflex, and, on occasions, postural tremor. measurement of caudate-putamen monoamine content at this time showed a profound loss in 3,4-dihydroxyphen ... | 1986 | 2428937 |
| polyhalogenated dibenzo-p-dioxins and dibenzofurans and the immune system. 1. effects on peripheral lymphocyte subpopulations of a non-human primate (callithrix jacchus) after treatment with 2,3,7,8-tetrachlorodibenzo-p-dioxin (tcdd). | monoclonal antibodies were used to analyse the effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (tcdd) on peripheral lymphocytes from marmosets (callithrix jacchus) following injections of single low doses of tcdd. a reduction of the percentage and the total number of lymphocytes among the white blood cells was seen 3 weeks after a single administration of 300 ng tcdd/kg body wt, but not following 167 ng tcdd/kg or less. after treatment of marmosets with the single subcutaneous dose of 10 ng tcdd/ ... | 1990 | 2403285 |
| the topology of the thalamo-cortical projections in the marmoset monkey (callithrix jacchus). | this paper addresses the question of a general topological principle of thalamo-cortical projections. in the lissencephalic primate brain of the common marmoset (callithrix jacchus), large injections of horseradish peroxidase were made in various parts of the neocortex. these injections were placed in different animals and hemispheres along various caudo-rostral and medio-lateral gradients. labelled cells in the thalamus were plotted and the labelling-zones resulting from several injections alon ... | 1990 | 2394218 |
| a lobster claw abnormality in the common marmoset (callithrix jacchus). | a congenital abnormality of the digits, similar to the 'lobster claw' deformity of humans, was observed in 8 common marmosets. the condition varied in severity and in effect on the animals; it appeared to be due to a single autosomal recessive trait. | 1990 | 2366513 |
| an ultrastructural study of early chorionic villus formation in the marmoset monkey (callithrix jacchus). | the ultrastructural morphology of developing chorionic villi in the marmoset monkey (callithrix jacchus) placenta was studied in pregnant monkeys at known time intervals after ovulation. in samples obtained at 45 days after ovulation the mesoderm, which consists of primitive foetal blood vessels, is seen to extend down into cytotrophoblast columns. syncytiotrophoblast completely surrounds maternal blood vessels and both basal laminae and endothelial cells of maternal origin show signs of disorga ... | 1990 | 2305971 |
| morphology of neuropeptide y-immunoreactive neurons in the cat olfactory bulb and olfactory peduncle: postnatal development and species comparison. | the distribution and morphology of neuropeptide y-immunoreactive (npy-ir) neurons in the olfactory bulb and the olfactory peduncle was studied in the adult cat and rat, and the common marmoset callithrix jacchus. significant species differences were not observed. in all three species, the population of npy-ir neurons is localized in the white matter extending from the main olfactory bulb to the border of the striatum. the neurons are characterized by a conspicuously looping axonal ramification p ... | 1990 | 2298945 |
| chromosomal evolution in callithrix emiliae. | we studied the karyotype of specimens of callithrix emiliae (callithricidae, primates) from rondonia, brazil. comparison with the karyotype of callithrix jacchus showed that, even though these two species show many karyotypic similarities, they differ by a robertsonian translocation, a paracentric inversion and large-scale addition of heterochromatin. the c. emiliae species appears to be in an active phase of chromosome evolution by the addition of constitutive heterochromatin. | 1992 | 2272240 |
| transmammary transmission of mesocercariae of alaria marcianae (trematoda) in experimentally infected primates. | a lactating primate, callithrix jacchus, was infected experimentally with 600 mesocercariae of alaria marcianae 10 days after parturition to determine if she would transmit the mesocercariae to her offspring. her twin infants were examined 4 wk postinoculation and 16 mesocercariae were found in their tissues. the female was mated again and gave birth to a litter of triplets. she was not given additional mesocercariae. one infant died within hours of birth without suckling and was found negative ... | 1990 | 2254822 |
| [radiotelemetric studies of the body temperature of white-tufted monkeys (callithrix jacchus)]. | a newly developed telemetry system was used to study deep body temperature (bt) of two adult male common marmosets (callithrix jacchus). the bt-curves of both monkeys showed a similar clear circadian rhythm with a range up to 3.5 degrees c. at environmental temperature of 28 degrees c (et) the bt of the monkeys varied in the daytime dependent on their spontaneous activity, with little individual differences between 37.5 degrees c and 39.3 degrees c; at night the bt of the remarkably deeply-sleep ... | 1990 | 2251862 |
| studies on the ascorbic acid metabolism of callitrichid monkeys by 14c isotope excretion technique. | recently it has been found that the two monkey species callithrix jacchus and saguinus fuscicollis, both belonging to the same new world monkey family callitrichidae and held in the same colony under identical conditions, had extremely different serum ascorbate levels. to examine the ascorbic acid metabolism the 14c-excretion of orally given 1-14c-ascorbic acid was studied under conditions of marginal and abundant vitamin c supply and under intentional stress. there were large differences in the ... | 1990 | 2251861 |
| extension of reproductive suppression by pheromonal cues in subordinate female marmoset monkeys, callithrix jacchus. | pheromonal signals from the dominant female marmoset monkey were implicated in maintaining the suppression of lh secretion and ovulation in socially subordinate females. when subordinate, and reproductively suppressed, female marmoset monkeys were removed from their group without scent contact with their dominant females, subordinate females in control group 1 (n = 8) and control group 2 (n = 5), ovulated 10.8 +/- 1.4 days and 10.4 +/- 0.8 days respectively (mean +/- s.e.m.) after separation. su ... | 1990 | 2250240 |
| [the distribution of different collagen types and laminin in the gingiva of the common marmoset (callithrix jacchus)]. | the distribution of the collagen types i, iii, iv, v, vi and of the glycoprotein laminin have been examined in the healthy gingiva of the marmoset with the indirect immunofluorescence method. it has been shown that collagen type i formed thick fibrils in a wave-like pattern, while collagen type iii formed thinner fibrils, especially under the epithelial basal membrane. collagen type iv and laminin showed a strong fluorescence in the basal membrane (epithelium, vessels, nerves). collagen type v h ... | 1990 | 2237364 |
| the facial artery of the common marmoset (callithrix jacchus). | the facial artery and its ramifications in 7 adult common marmosets (callithrix jacchus) were studied by the plastic injection method. the findings obtained are discussed in comparison with those for other primates. in the submandibular region, the facial artery arose from the external carotid artery at the height of the atlas via the linguofacial trunk on 10 of the total of 14 sides examined and independently on the other 4 sides. this common trunk always gave rise to the superior thyroid arter ... | 1990 | 2216318 |
| screening procedure for assessment of ototoxicity in the common marmoset. | detection of drug-induced ototoxicity in safety evaluation studies of novel chemical entities is rarely attempted. where such examinations are included, they usually rely on reflex testing. the brainstem auditory evoked response can be measured with the use of externally positioned electrodes, and it monitors electrophysiologic responses to sound from the cochlear nerve and associated structures of the 8th cranial nerve. these responses have been reproducibly measured in sedated marmosets and th ... | 1990 | 2214803 |
| inhibin secretion during the ovulatory cycle and pregnancy in the common marmoset monkey. | changes in plasma concentrations of immunoreactive inhibin in the reproductively cyclic, pregnant and ovariectomized female marmoset monkey (callithrix jacchus) were measured with a heterologous radioimmunoassay. the pattern of inhibin secretion in five marmosets studied individually during four consecutive cycles was shown to resemble that of progesterone. in these animals, data were pooled according to stage of cycle on the basis of plasma progesterone concentrations. mean values for inhibin w ... | 1990 | 2212937 |
| adenocarcinoma of the small intestine in a common marmoset (callithrix jacchus). | 1990 | 2157108 | |
| monoclonal antibodies from epstein-barr virus-transformed lymphocytes of common marmosets (callithrix jacchus) immune to malaria. | the b lymphocytes of the common marmoset callithrix jacchus can be immortalized by infection with epstein-barr virus (ebv) in vitro (desgranges et al., 1976). c. jacchus is susceptible to infection with the blood stages of several species of malaria parasite including the line designated mvf1 (mitchell et al., 1988) from which it recovers and shows immunity to reinfection. by exploiting these two phenomena, ebv-transformed, marmoset lymphoblastoid cell lines secreting antibodies to malaria paras ... | 1990 | 2155967 |
| transfer of various polychlorinated dibenzo-p-dioxins and dibenzofurans (pcdds and pcdfs) via placenta and through milk in a marmoset monkey. | a defined mixture of polychlorinated dibenzo-p-dioxins and dibenzofurans (pcdds and pcdfs) was subcutaneously administered to a pregnant marmoset monkey (callithrix jacchus) 11 weeks prior to delivery. transfer of pcdds and pcdfs via placenta and mother's milk was investigated by measurement of concentrations in a newborn 1 day after birth and in an infant of the same litter after a lactation period of 33 days. furthermore, comparative measurements were performed in different tissues of the moth ... | 1990 | 2128593 |
| persistence of various polychlorinated dibenzo-p-dioxins and dibenzofurans (pcdds and pcdfs) in hepatic and adipose tissue of marmoset monkeys. | a defined mixture of polychlorinated dibenzo-p-dioxins and dibenzofurans (pcdds and pcdfs) was subcutaneously administered to marmoset monkeys (callithrix jacchus). tissue concentrations in hepatic and adipose tissue were measured at different times after treatment (1-28 weeks). one week after application high concentrations could be detected for the 2,3,7,8-substituted congeners only. the percent of the administered dose in whole liver differed for the various 2,3,7,8-substituted congeners, ran ... | 1990 | 2125825 |
| n-3 and n-6 phosphoglyceride fatty acids in relation to in vitro erythrocyte haemolysis induced by hydrogen peroxide in captive common marmosets (callithrix jacchus). | 1. hydrogen peroxide-induced haemolysis (hpih) was studied in the red blood cells of the common marmoset monkey (callithrix jacchus) in relation to the composition of the membrane fatty acids. hpih (%) was surprisingly high (mean 41% +/- 34; median 33.4%) and significantly different (p less than 0.001) from the corresponding value in healthy human subjects (mean 0.98% +/- 0.6; median 1.3%). 2. it was negatively correlated with 18:2n-6 (r = -0.76, p less than 0.001), 18:2n-6/20:4n-6 (r = -0.70, p ... | 1990 | 2123763 |
| immunofluorescence-microscopic localization of collagen type iv and vi, laminin and nidogen in the livers of callithrix jacchus during pre- and postnatal development. | the distribution of collagen type iv and vi, laminin and nidogen was investigated by immunofluorescence microscopy in the livers of marmosets (callithrix jacchus) at various stages of development, i.e. on days 93, 111, 116 and 134 of gestation, 1 day postpartum and at the mature stage. large amounts of collagen type iv could in all cases be demonstrated in the sinus wall and in all basal laminae outside the lobule. after the application of antibodies against collagen type vi the sinus wall showe ... | 1990 | 2117839 |
| 1-methyl-4-(2'-methylphenyl)-1,2,3,6-tetrahydropyridine (2'-methyl-mptp) is less neurotoxic than mptp in the common marmoset. | four adult marmosets were treated with increasing doses of 1-methyl-4-(2'-methylphenyl)-1,2,3,6-tetrahydropyridine (2'-methyl-mptp) in the range 0.23-4.3 mg/kg i.p. to give a cumulative dose of 11.0-11.6 mg/kg over a 6-10 day period. after 4 days of treatment, and as the dosage was gradually increased, the animals exhibited mild motor deficits. these abnormalities slowly declined over the following 1-6 week period. in contrast, similar treatment of common marmosets with 1-methyl-4-phenyl-1,2,3,6 ... | 1990 | 2117541 |