Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
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| the fielding h. garrison lecture: "break-bone" fever in philadelphia, 1780: reflections on the history of disease. | in the autumn of 1780 an epidemic hit the city of philadelphia. the symptoms of the disease resembled those of present day dengue fever, and subsequent observers argued that the disease was in fact dengue. but was it? the question forces us to confront the challenges of retrospective epidemiology and how we examine the history of a disease. this paper examines the 1780 epidemic from two perspectives. first, it looks at evidence that the disease was dengue and examines what this tells us about th ... | 0 | 27374846 |
| sarcoptes scabiei: genomics to proteomics to biology. | the common scabies mite, sarcoptes scabiei is a cosmopolitan parasite of humans and other mammals. an annotated genome of sarcoptes scabiei var. canis has been deposited in the national center for biotechnology information (ncbi) and vectorbase and a proteomic analysis of proteins in extracts of mite bodies and eggs from this strain has been reported. here we mined the data to identify predicted proteins that are known to be involved in specific biological processes in other animals. | 2016 | 27371026 |
| development of neutralization assay using an egfp chikungunya virus. | chikungunya virus (chikv), a member of the alphavirus genus, is an important human emerging/re-emerging pathogen. currently, there are no effective antiviral drugs or vaccines against chikv infection. herein, we construct an infectious clone of chikv and an egfp reporter chikv (egfp-chikv) with an isolated strain (assigned to asian lineage) from chikv-infected patients. the egfp-chikv reporter virus allows for direct visualization of viral replication through the levels of egfp expression. using ... | 2016 | 27367716 |
| structure and functional diversity of gcn5-related n-acetyltransferases (gnat). | general control non-repressible 5 (gcn5)-related n-acetyltransferases (gnat) catalyze the transfer of an acyl moiety from acyl coenzyme a (acyl-coa) to a diverse group of substrates and are widely distributed in all domains of life. this review of the currently available data acquired on gnat enzymes by a combination of structural, mutagenesis and kinetic methods summarizes the key similarities and differences between several distinctly different families within the gnat superfamily, with an emp ... | 2016 | 27367672 |
| toxicity of squamocin on aedes aegypti larvae, its predators and human cells. | the mosquito aedes aegypti transmits a virus that causes diverse human diseases, and control of the vector is an important strategy to avoid disease propagation. plants in the family annonaceae are recognised as sources of molecules with uses in the medical and agriculture fields. molecules of secondary metabolites of annonaceae plants exhibit insecticidal potential against insect pests and vectors, especially acetogenins, showing high toxicity at low doses, which has encouraged research into pr ... | 2017 | 27366879 |
| using phenomenological models to characterize transmissibility and forecast patterns and final burden of zika epidemics. | the world health organization declared the ongoing zika virus (zikv) epidemic in the americas a public health emergency of international concern on february 1, 2016. zikv disease in humans is characterized by a "dengue-like" syndrome including febrile illness and rash. however, zikv infection in early pregnancy has been associated with severe birth defects, including microcephaly and other developmental issues. mechanistic models of disease transmission can be used to forecast trajectories and l ... | 2016 | 27366586 |
| genetically modified (gm) mosquito use to reduce mosquito-transmitted disease in the us: a community opinion survey. | mosquito-borne infectious diseases such as dengue, chikungunya, and now zika, pose a public health threat to the us, particularly florida, the gulf coast states, and hawaii. recent autochthonous transmission of dengue and chikungunya in florida, the recent dengue outbreak in hawaii, and the potential for future local spread of zika in the us, has led to the consideration of novel approaches to mosquito management. one such novel approach, the release of sterile genetically modified mosquitoes, h ... | 2016 | 27366585 |
| first imported case of chikungunya virus infection in a travelling canadian returning from the caribbean. | this is the first canadian case of chikungunya virus (chikv) infection reported in a traveller returning from the caribbean. following multiple mosquito bites in martinique island in january 2014, the patient presented with high fever, headaches, arthralgia on both hands and feet, and a rash on the trunk upon his return to canada. initial serological testing for dengue virus infection was negative. support therapy with nonsteroidal anti-inflammatory drugs was administered. the symptoms gradually ... | 2016 | 27366163 |
| deadly intracranial bleed in patients with dengue fever: a series of nine patients and review of literature. | dengue fever is a global pandemic threat with increasing incidence. to date, there are no cures and the effectiveness of dengue vaccines is still uncertain. world heath organization introduced expanded dengue syndrome to include unusual presentations of dengue fever including severe neurologic complications. one of the deadly complications is intracranial hemorrhage (ich). | 0 | 27365962 |
| chikungunya fever among patients with acute febrile illness attending a tertiary care hospital in mumbai. | chikungunya fever (chik) is an arboviral disease. dengue fever (deng) and chik are indistinguishable clinically and need to be differentiated by laboratory investigations. | 0 | 27365916 |
| flightless aedes mosquitoes in dengue control. | 2011 | 27365801 | |
| the wmel strain of wolbachia reduces transmission of zika virus by aedes aegypti. | zika virus (zikv) is causing an explosive outbreak of febrile disease in the americas. there are no effective antiviral therapies or licensed vaccines for this virus, and mosquito control strategies have not been adequate to contain the virus. a promising candidate for arbovirus control and prevention relies on the introduction of the intracellular bacterium wolbachia into aedes aegypti mosquitoes. this primarily has been proposed as a tool to control dengue virus (denv) transmission; however, e ... | 2016 | 27364935 |
| infectivity of immature neurons to zika virus: a link to congenital zika syndrome. | epidemiological data strongly suggest that microcephaly cases in brazil are associated with the ongoing epidemic of zika virus (zikv). in order to further solidify the possible link, we investigated the infectivity of zikv using various neuroblastoma (nb) cell lines. | 2016 | 27364784 |
| gut bacteria differentially affect egg production in the anautogenous mosquito aedes aegypti and facultatively autogenous mosquito aedes atropalpus (diptera: culicidae). | aedes aegypti and a. atropalpus are related mosquitoes that differ reproductively. aedes aegypti must blood-feed to produce eggs (anautogenous) while a. atropalpus always produces a first clutch of eggs without blood-feeding (facultatively autogenous). we recently characterized the gut microbiota of a. aegypti and a. atropalpus that were reared identically in the laboratory. here, we assessed the effects of specific members of the gut microbiota in a. aegypti and a. atropalpus on female fitness ... | 2016 | 27363842 |
| studies on aedes aegypti resistance to some insecticides in the jazan district, saudi arabia. | the present study provided information on the susceptibility status of the adult and larvae of aedes aegypti mosquitoes in jazan region of saudi arabia. bioassay tests were performed on adults and larvae by using who recommended concentrations and test kits. adults of ae. aegypti mosquitoes were exposed to test papers impregnated with lambda-cyhalothrin (0.05%), cyfluthrin (0.15%), deltamethrin (0.05%), permethrin (0.75%), fenitrothion (1%), bendiocarb (0.1%) and ddt (4%) insecticides. ae. aegyp ... | 2016 | 27363057 |
| rapid and non-destructive detection and identification of two strains of wolbachia in aedes aegypti by near-infrared spectroscopy. | the release of wolbachia infected mosquitoes is likely to form a key component of disease control strategies in the near future. we investigated the potential of using near-infrared spectroscopy (nirs) to simultaneously detect and identify two strains of wolbachia pipientis (wmelpop and wmel) in male and female laboratory-reared aedes aegypti mosquitoes. our aim is to find faster, cheaper alternatives for monitoring those releases than the molecular diagnostic techniques that are currently in us ... | 2016 | 27362709 |
| pirna pathway is not required for antiviral defense in drosophila melanogaster. | since its discovery, rna interference has been identified as involved in many different cellular processes, and as a natural antiviral response in plants, nematodes, and insects. in insects, the small interfering rna (sirna) pathway is the major antiviral response. in recent years, the piwi-interacting rna (pirna) pathway also has been implicated in antiviral defense in mosquitoes infected with arboviruses. using drosophila melanogaster and an array of viruses that infect the fruit fly acutely o ... | 2016 | 27357659 |
| assessment of angelica sinensis (oliv.) diels as a repellent for personal protection against mosquitoes under laboratory and field conditions in northern thailand. | angelica sinensis (oliv.) hexane extract (ahe) has been reported as a proven and impressive repellent against laboratory-reared female aedes aegypti mosquitoes. with the aim of promoting products of plant origin as a viable alternative to conventional synthetic substances, this study was designed to transform ahe-based repellents for exploitable commercial production by enhancing their efficacy and assessing their physical and biological stability as well as repellency against mosquitoes under l ... | 2016 | 27357395 |
| vector competence of aedes aegypti in transmitting chikungunya virus: effects and implications of extrinsic incubation temperature on dissemination and infection rates. | aedes aegypti is a competent arthropod vector of chikungunya virus (chikv). the rate at which the virus disseminate in the vector is limited by temperature of their environment which can be an important determinant of geographical and seasonal limits to transmission by the arthropods in the tropics. this study investigated the vector competence of ae. aegypti for chikv at ambient temperature of 32 and 26 °c (coastal and western kenya respectively) reared at extrinsic incubation temperature (eit) ... | 2016 | 27357190 |
| identification and characterization of ige-binding tropomyosins in aedes aegypti. | the mosquito aedes aegypti is a potential source of important clinically relevant allergens. however, the allergenicity and cross-reactivity of most of these has not been fully described. | 2016 | 27355916 |
| emerging arboviruses and public health challenges in brazil. | environmental modification by anthropogenic actions, disordered urban growth, globalization of international exchange and climate change are some factors that help the emergence and dissemination of human infectious diseases transmitted by vectors. this review discusses the recent entry of three arboviruses in brazil: chikungunya, west nile, and zika virus, focusing on the challenges for the country's public health. the brazilian population is exposed to infections caused by these three arboviru ... | 0 | 27355468 |
| ethnopharmacological significance of eclipta alba (l.) hassk. (asteraceae). | eclipta alba can be found growing wild in fallow lands of bangladesh where it is considered as a weed by farmers. traditional medicinal systems of the indian subcontinent countries as well as tribal practitioners consider the plant to have diverse medicinal values and use it commonly for treatment of gastrointestinal disorders, respiratory tract disorders (including asthma), fever, hair loss and graying of hair, liver disorders (including jaundice), skin disorders, spleen enlargement, and cuts a ... | 2014 | 27355071 |
| endosymbiotic bacteria associated with the mealy bug, rhizoecus amorphophalli (hemiptera: pseudococcidae). | the mealy bug, rhizoecus amorphophalli, is a menace to the aroid farmers due to the intensive infestation on stored tubers. spraying of pesticides was able to control this pest but it always left a chance for fungal growth. bacterial endosymbionts associated with the insects provide several benefits to their host. since such endosymbionts play a vital role even in the physiology of their host, revealing the types of bacteria associated with mealy bug will give basic information, which may throw ... | 2014 | 27355014 |
| the eye of the tiger, the thrill of the fight: effective larval and adult control measures against the asian tiger mosquito, aedes albopictus (diptera: culicidae), in north america. | the asian tiger mosquito, aedes albopictus (skuse), is a highly invasive container-inhabiting species with a global distribution. this mosquito, similar to other stegomyia species such as aedes aegypti (l.), is highly adapted to urban and suburban areas, and commonly oviposits in artificial containers, which are ubiquitous in these peridomestic environments. the increase in speed and amount of international travel and commerce, coupled with global climate change, have aided in the resurgence and ... | 2016 | 27354440 |
| dengue virus genome uncoating requires ubiquitination. | the process of genome release or uncoating after viral entry is one of the least-studied steps in the flavivirus life cycle. flaviviruses are mainly arthropod-borne viruses, including emerging and reemerging pathogens such as dengue, zika, and west nile viruses. currently, dengue virus is one of the most significant human viral pathogens transmitted by mosquitoes and is responsible for about 390 million infections every year around the world. here, we examined for the first time molecular aspect ... | 2016 | 27353759 |
| molecular docking and simulation studies of gustatory receptor of aedes aegypti: a potent drug target to distract host-seeking behaviour in mosquitoes. | it is well reported that exhaled co 2 and skin odour from human being assist female mosquitoes to locate human host. basically, the receptors for this activity are expressed in cpa neurons. in both aedes aegypti and anopheles gambiae, this co 2-sensitive olfactory neuron detects myriad number of chemicals present in human skin. therefore, manipulation of gustatory receptors housing these neurons may serve as important targets for behavioural intervention. the study was aimed towards virtual scre ... | 2017 | 27353589 |
| molecular identification of aedes aegypti mosquitoes from pilani region of rajasthan, india. | aedes aegypti is the most important vector of dengue virus infection in humans worldwide. accurate identification and colonization are the essential requirements to understand vector biology as well as its diseases transmission potential. in this study, we have used molecular approaches for the identification of ae. aegypti mosquitoes that were collected from the pilani region of rajasthan, india methods: field collected mosquito larvae were colonized under laboratory conditions. conserved genet ... | 2017 | 27353585 |
| impact of container material on the development of aedes aegypti larvae at different temperatures. | aedes aegypti, the primary vector of dengue generally breeds in intradomestic and peridomestic containers made up of different materials, i.e. plastic, iron, rubber, earthen material etc. the material of container is likely to affect the temperature of water in container with variation in environmental temperature. the present study was aimed to determine the effect of different container materials on larval development of ae. aegypti at different temperatures. | 2017 | 27353584 |
| spatial distribution and insecticide susceptibility status of aedes aegypti and aedes albopictus in dengue affected urban areas of rawalpindi, pakistan. | dengue is one of the most common arthropod-borne viral diseases which is transmitted mainly by two vector species, aedes aegypti (linnaeus 1762) and ae. albopictus (skuse, 1894) worldwide. as there is no effective medicine and vaccine available, vector control remains the most effective measure to prevent its transmission and outbreak. the aim of the study was to confirm the co-occurrence of aedes aegypti and ae. albopictus populations in the different localities of rawalpindi, pakistan and exam ... | 2017 | 27353583 |
| spatial analysis of wing geometry in dengue vector mosquito, aedes aegypti (l.) (diptera: culicidae), populations in metropolitan manila, philippines. | aedes aegypti (l.) is an efficient vector for arboviral diseases such as dengue. the wings of ae. aegypti has been extensively studied in order to investigate population heterogeneity and structure by utilizing a landmark based geometric morphometrics (gms) approach. the aim of this study was to examine and assess the wing geometry of ae. aegypti in metropolitan manila. | 2017 | 27353582 |
| pseudomonas aeruginosa kun2, extracellular toxins-a potential source for the control of dengue vector. | dengue fever is one of the serious health disease transmitted by aedes spp mosquitoes. the incidence of dengue has increased dramatically around the world in recent decades. vector control is one of the important strategies practiced for the control of dengue fever. the emergence of resistance among vectors against the existing insecticides has raised new challenges. the aim of the present study was to identify the larvicidal activity of extracellular toxins from pseudomonas spp for the control ... | 2017 | 27353579 |
| the strica homolog aacasps16 is involved in apoptosis in the yellow fever vector, aedes albopictus. | caspases are a family of cysteine proteases playing essential roles during apoptosis. seven caspases identified in drosophila were dronc, dredd, strica, dcp-1, decay, drice and damm. among them, strica is an insect-specific caspase containing a long serine- and threonine- rich prodomain, of which function is not yet well studied. here we identified a homolog of strica from aedes albopictus, named as aacasps16. aacasps16 encoded a protein containing a putative serine- and threonine-rich prodomain ... | 2016 | 27351972 |
| analysis of the differentiation of kenyon cell subtypes using three mushroom body-preferential genes during metamorphosis in the honeybee (apis mellifera l.). | the adult honeybee (apis mellifera l.) mushroom bodies (mbs, a higher center in the insect brain) comprise four subtypes of intrinsic neurons: the class-i large-, middle-, and small-type kenyon cells (lkcs, mkcs, and skcs, respectively), and class-ii kcs. analysis of the differentiation of kc subtypes during metamorphosis is important for the better understanding of the roles of kc subtypes related to the honeybee behaviors. in the present study, aiming at identifying marker genes for kc subtype ... | 2016 | 27351839 |
| detection of dengue, west nile virus, rickettsiosis and leptospirosis by a new real-time pcr strategy. | dengue virus (denv) infection causes sudden fever along with several nonspecific signs and symptoms and in severe cases, death. denv is transmitted to people by aedes aegypti and ae. albopictus mosquitoes, whose populations increase during rainy season. west nile virus (wnv), rickettsia spp. and leptospira spp. are fever-causing pathogens that share many of the initial symptoms of denv infection and also thrive in the rainy season. outbreaks in some regions may be due to any of these pathogens t ... | 2016 | 27350908 |
| functional analysis of orco and odorant receptors in odor recognition in aedes albopictus. | aedes albopictus is a globally invasive mosquito and a major vector of arboviruses, including dengue, zika and chikungunya. olfactory-related behaviors, particularly host-seeking, offer opportunities to disrupt the disease-transmission process. a better understanding of odorant receptors (ors) may assist in explaining host selection and location, and contribute to novel strategy of vector control. | 2016 | 27350348 |
| alarm variables for dengue outbreaks: a multi-centre study in asia and latin america. | worldwide, dengue is an unrelenting economic and health burden. dengue outbreaks have become increasingly common, which place great strain on health infrastructure and services. early warning models could allow health systems and vector control programmes to respond more cost-effectively and efficiently. | 2016 | 27348752 |
| chikungunya virus in febrile humans and aedes aegypti mosquitoes, yucatan, mexico. | chikungunya virus (chikv) was isolated from 12 febrile humans in yucatan, mexico, in 2015. one patient was co-infected with dengue virus type 1. two additional chikv isolates were obtained from aedes aegypti mosquitoes collected in the homes of patients. phylogenetic analysis showed that the chikv isolates belong to the asian lineage. | 2016 | 27347760 |
| bioinformatic characterization of mosquito viromes within the eastern united states and puerto rico: discovery of novel viruses. | mosquitoes are efficient, militarily relevant vectors of infectious disease pathogens, including many rna viruses. the vast majority of all viruses are thought to be undiscovered. accordingly, recent studies have shown that viruses discovered in insects are very divergent from known pathogens and that many of them lack appropriate reference sequences in the public databases. given that the majority of viruses are likely still undiscovered, environ mental sampling stands to provide much needed re ... | 2016 | 27346944 |
| assessing seasonal risks for the introduction and mosquito-borne spread of zika virus in europe. | the explosive zika virus epidemic in the americas is amplifying spread of this emerging pathogen into previously unaffected regions of the world, including europe (gulland, 2016), where local populations are immunologically naïve. as summertime approaches in the northern hemisphere, aedes mosquitoes in europe may find suitable climatic conditions to acquire and subsequently transmit zika virus from viremic travellers to local populations. while aedes albopictus has proven to be a vector for the ... | 2016 | 27344225 |
| genome-wide survey of gut fungi (harpellales) reveals the first horizontally transferred ubiquitin gene from a mosquito host. | harpellales, an early-diverging fungal lineage, is associated with the digestive tracts of aquatic arthropod hosts. concurrent with the production and annotation of the first four harpellales genomes, we discovered that zancudomyces culisetae, one of the most widely distributed harpellales species, encodes an insect-like polyubiquitin chain. ubiquitin and ubiquitin-like proteins are universally involved in protein degradation and regulation of immune response in eukaryotic organisms. phylogeneti ... | 2016 | 27343289 |
| comparative proteome analysis reveals that blood and sugar meals induce differential protein expression in aedes aegypti female heads. | aedes aegypti females ingest sugar or blood to obtain the nutrients needed to maintain cellular homeostasis. during human blood ingestion, female mosquitoes may transmit different viruses such as dengue, yellow fever and, more recently, zika and chikungunya. here, we report changes in protein expression in the heads of adult female ae. aegypti mosquitoes in response to the ingestion of blood or sugar. proteins extracted from the heads of ae. aegypti fed exclusively on blood (bf) or sugar (sf) we ... | 2016 | 27343150 |
| redeployment of a conserved gene regulatory network during aedes aegypti development. | changes in gene regulatory networks (grns) underlie the evolution of morphological novelty and developmental system drift. the fruitfly drosophila melanogaster and the dengue and zika vector mosquito aedes aegypti have substantially similar nervous system morphology. nevertheless, they show significant divergence in a set of genes co-expressed in the midline of the drosophila central nervous system, including the master regulator single minded and downstream genes including short gastrulation, s ... | 2016 | 27341759 |
| isolation of infective zika virus from urine and saliva of patients in brazil. | zika virus (zikv) is an emergent threat provoking a worldwide explosive outbreak. since january 2015, 41 countries reported autochthonous cases. in brazil, an increase in guillain-barré syndrome and microcephaly cases was linked to zikv infections. a recent report describing low experimental transmission efficiency of its main putative vector, ae. aegypti, in conjunction with apparent sexual transmission notifications, prompted the investigation of other potential sources of viral dissemination. ... | 2016 | 27341420 |
| comparative mt genomics of the tipuloidea (diptera: nematocera: tipulomorpha) and its implications for the phylogeny of the tipulomorpha. | a traditionally controversial taxon, the tipulomorpha has been frequently discussed with respect to both its familial composition and relationships with other nematocera. the interpretation of internal relationships within the tipuloidea, which include the tipulidae sensu stricto, cylindrotomidae, pediciidae and limoniidae, is also problematic. we sequenced the first complete mitochondrial (mt) genome of symplecta hybrida (meigen, 1804), which belongs to the subfamily chioneinae of family limoni ... | 2016 | 27341029 |
| dengue virus sero-cross-reactivity drives antibody-dependent enhancement of infection with zika virus. | zika virus (zikv) was discovered in 1947 and was thought to lead to relatively mild disease. the recent explosive outbreak of zikv in south america has led to widespread concern, with reports of neurological sequelae ranging from guillain barré syndrome to microcephaly. zikv infection has occurred in areas previously exposed to dengue virus (denv), a flavivirus closely related to zikv. here we investigated the serological cross-reaction between the two viruses. plasma immune to denv showed subst ... | 2016 | 27339099 |
| screening of blood donations for zika virus infection - puerto rico, april 3-june 11, 2016. | transfusion-transmitted infections have been documented for several arboviruses, including west nile and dengue viruses (1). zika virus, a flavivirus transmitted primarily by aedes aegypti mosquitoes that has been identified as a cause of congenital microcephaly and other serious brain defects (2), became recognized as a potential threat to blood safety after reports from a 2013-2014 outbreak in french polynesia. blood safety concerns were based on very high infection incidence in the population ... | 2016 | 27337368 |
| the current status of zika virus in southeast asia. | zika virus currently poses a global threat and is a major public health issue throughout latin america and the caribbean. however, zika virus infections in humans have also been observed in other regions, including southeast asia, where arboviral diseases are very common. in this study, we summarize the current status of zika virus in southeast asia. this review aims to provide an overview of the current situation and also to suggest ways of adequately managing the emergence of zika virus in sou ... | 2016 | 27336445 |
| larvicidal efficacies of plants from midwestern brazil: melianodiol from guarea kunthiana as a potential biopesticide against aedes aegypti. | a total of 36 ethanol extracts from different anatomical parts of 27 plant species (18 families), native to the pantanal and cerrado biomes in midwest brazil, was assessed for their effect against aedes aegypti larvae, the vector of dengue, hemorrhagic dengue, zika and chikungunya fevers. only the extract obtained from seeds of guarea kunthiana (meliaceae) proved active (lc50 = 169.93 μg/ml). a bioassay-guided investigation of this extract led to the isolation and identification of melianodiol, ... | 0 | 27333366 |
| spatial and temporal hot spots of aedes albopictus abundance inside and outside a south european metropolitan area. | aedes albopictus is a tropical invasive species which in the last decades spread worldwide, also colonizing temperate regions of europe and us, where it has become a public health concern due to its ability to transmit exotic arboviruses, as well as severe nuisance problems due to its aggressive daytime outdoor biting behaviour. while several studies have been carried out in order to predict the potential limits of the species expansions based on eco-climatic parameters, few studies have so far ... | 2016 | 27333276 |
| the when and the where of zika epidemic potential in europe - an evidence base for public health preparedness. | 2016 | 27333025 | |
| host inflammatory response to mosquito bites enhances the severity of arbovirus infection. | aedes aegypti mosquitoes are responsible for transmitting many medically important viruses such as those that cause zika and dengue. the inoculation of viruses into mosquito bite sites is an important and common stage of all mosquito-borne virus infections. we show, using semliki forest virus and bunyamwera virus, that these viruses use this inflammatory niche to aid their replication and dissemination in vivo. mosquito bites were characterized by an edema that retained virus at the inoculation ... | 0 | 27332734 |
| deep sequencing-based transcriptome analysis reveals the regulatory mechanism of bemisia tabaci (hemiptera: aleyrodidae) nymph parasitized by encarsia sophia (hymenoptera: aphelinidae). | the whitefly bemisia tabaci is a genetically diverse complex with multiple cryptic species, and some are the most destructive invasive pests of many ornamentals and crops worldwide. encarsia sophia is an autoparasitoid wasp that demonstrated high efficiency as bio-control agent of whiteflies. however, the immune mechanism of b. tabaci parasitization by e. sophia is unknown. in order to investigate immune response of b. tabaci to e. sophia parasitization, the transcriptome of e. sophia parasitize ... | 2016 | 27332546 |
| epidemiology of chikungunya virus in bahia, brazil, 2014-2015. | chikungunya is an emerging arbovirus that is characterized into four lineages. one of these, the asian genotype, has spread rapidly in the americas after its introduction in the saint martin island in october 2013. unexpectedly, a new lineage, the east-central-south african genotype, was introduced from angola in the end of may 2014 in feira de santana (fsa), the second largest city in bahia state, brazil, where over 5,500 cases have now been reported. number weekly cases of clinically confirmed ... | 2016 | 27330849 |
| identify-isolate-inform: a tool for initial detection and management of zika virus patients in the emergency department. | first isolated in 1947 from a monkey in the zika forest in uganda, and from mosquitoes in the same forest the following year, zika virus has gained international attention due to concerns for infection in pregnant women potentially causing fetal microcephaly. more than one million people have been infected since the appearance of the virus in brazil in 2015. approximately 80% of infected patients are asymptomatic. an association with microcephaly and other birth defects as well as guillain-barre ... | 2016 | 27330653 |
| susceptibility to temephos and spinosad in aedes aegypti (diptera: culicidae) from puerto rico. | we examined the susceptibility to temephos and spinosad (natular ec) of eight aedes aegypti (l.) populations from puerto rico, following who method (who 2005). enzyme activity was measured for alpha- and beta-esterases, multiple function oxidases, glutathione-s-transferases, and insensitive acetylcholinesterase and was tested for correlation with the susceptibility level. the results showed that larval populations from puerto rico obtained during 2014 were found to be susceptible to both larvici ... | 2016 | 27330095 |
| has rift valley fever virus evolved with increasing severity in human populations in east africa? | rift valley fever (rvf) outbreaks have occurred across eastern africa from 1912 to 2010 approximately every 4-15 years, most of which have not been accompanied by significant epidemics in human populations. however, human epidemics during rvf outbreaks in eastern africa have involved 478 deaths in 1998, 1107 reported cases with 350 deaths from 2006 to 2007 and 1174 cases with 241 deaths in 2008. we review the history of rvf outbreaks in eastern africa to identify the epidemiological factors that ... | 2016 | 27329846 |
| structural characterization and evaluation of mosquito-larvicidal property of silver nanoparticles synthesized from the seaweed, turbinaria ornata (turner) j. agardh 1848. | the silver nanoparticles synthesized from turbinaria ornata (to-agnps) showed spherical with crystalline nature (20-32 nm) was evaluated against fourth instar larvae of three mosquitoes. the maximum activity of to-agnps was recorded on aedes aegypti followed by anopheles stephensi and culex quinquefasciatus with the following lethal concentration values (μg/ml): lc50 of 0.738, 1.134, and 1.494; and lc90 of 3.342, 17.982, and 22.475, respectively. the obtained respective values (μg/ml) vis-a-vis ... | 2016 | 27327539 |
| temporal frequency of knockdown resistance mutations, f1534c and v1016g, in aedes aegypti in chiang mai city, thailand and the impact of the mutations on the efficiency of thermal fogging spray with pyrethroids. | in thailand, control of dengue outbreaks is currently attained by the use of space sprays, particularly thermal fogging using pyrethroids, with the aim of killing infected aedes mosquito vectors in epidemic areas. however, the principal dengue vector, aedes aegypti, is resistant to pyrethroids conferred mainly by mutations in the voltage-gated sodium channel gene, f1534c and v1016g, termed knockdown resistance (kdr). the objectives of this study were to determine the temporal frequencies of f153 ... | 2016 | 27325294 |
| seroprevalence of anti-chikungunya virus antibodies in children and adults in managua, nicaragua, after the first chikungunya epidemic, 2014-2015. | chikungunya is a viral disease transmitted by aedes aegypti and ae. albopictus mosquitoes. in late 2013, chikungunya virus (chikv) was introduced into the caribbean island of st. martin. since then, approximately 2 million chikungunya cases have been reported by the pan american health organization, and most countries in the americas report autochthonous transmission of chikv. in nicaragua, the first imported case was described in july 2014 and the first autochthonous case in september 2014. her ... | 2016 | 27322692 |
| seasonal differences in density but similar competitive impact of aedes albopictus (skuse) on aedes aegypti (l.) in rio de janeiro, brazil. | previous studies have shown that the negative effects of density of ae. albopictus on ae. aegypti exceed those of ae. aegypti on ae. albopictus for population growth, adult size, survivorship, and developmental rate. this competitive superiority has been invoked to explain the displacement of ae. aegypti by ae. albopictus in the southeastern usa. in brazil, these species coexist in many vegetated suburban and rural areas. we investigated a related, but less-well-studied question: do effects of a ... | 2016 | 27322537 |
| climate change and aedes vectors: 21st century projections for dengue transmission in europe. | warming temperatures may increase the geographic spread of vector-borne diseases into temperate areas. although a tropical mosquito-borne viral disease, a dengue outbreak occurred in madeira, portugal, in 2012; the first in europe since 1920s. this outbreak emphasizes the potential for dengue re-emergence in europe given changing climates. we present estimates of dengue epidemic potential using vectorial capacity (vc) based on historic and projected temperature (1901-2099). vc indicates the vect ... | 2016 | 27322480 |
| epidemic resurgence of dengue fever in singapore in 2013-2014: a virological and entomological perspective. | dengue resurged in singapore during 2013-14, causing an outbreak with unprecedented number of cases in the country. in the present study, we summarise the epidemiological, virological and entomological findings gathered through the dengue surveillance programme and highlight the drivers of the epidemic. we also describe how the surveillance system facilitated the preparedness to moderate epidemic transmission of dengue in the country. | 2016 | 27316694 |
| the mouthparts enriched odorant binding protein 11 of the alfalfa plant bug adelphocoris lineolatus displays a preferential binding behavior to host plant secondary metabolites. | odorant binding proteins (obps) are proposed to be directly required for odorant discrimination and represent potential interesting targets for pest control. in the notoriously agricultural pest adelphocoris lineolatus, our previous functional investigation of highly expressed antennal obps clearly supported this viewpoint, whereas the findings of the current study by characterizing of alinobp11 rather indicated that obp in hemipterous plant bugs might fulfill a different and tantalizing physiol ... | 2016 | 27313540 |
| prevention and control of zika as a mosquito-borne and sexually transmitted disease: a mathematical modeling analysis. | the ongoing zika virus (zikv) epidemic in the americas poses a major global public health emergency. while zikv is transmitted from human to human by bites of aedes mosquitoes, recent evidence indicates that zikv can also be transmitted via sexual contact with cases of sexually transmitted zikv reported in argentina, canada, chile, france, italy, new zealand, peru, portugal, and the usa. yet, the role of sexual transmission on the spread and control of zikv infection is not well-understood. we i ... | 2016 | 27312324 |
| mating-induced increase in germline stem cells via the neuroendocrine system in female drosophila. | mating and gametogenesis are two essential components of animal reproduction. gametogenesis must be modulated by the need for gametes, yet little is known of how mating, a process that utilizes gametes, may modulate the process of gametogenesis. here, we report that mating stimulates female germline stem cell (gsc) proliferation in drosophila melanogaster. mating-induced increase in gsc number is not simply owing to the indirect effect of emission of stored eggs, but rather is stimulated by a ma ... | 2016 | 27310920 |
| mosquito saliva increases endothelial permeability in the skin, immune cell migration, and dengue pathogenesis during antibody-dependent enhancement. | dengue remains the most prevalent arthropod-borne viral disease in humans. while probing for blood vessels, aedes aegypti and ae. albopictus mosquitoes transmit the four serotypes of dengue virus (denv1-4) by injecting virus-containing saliva into the skin. even though arthropod saliva is known to facilitate transmission and modulate host responses to other pathogens, the full impact of mosquito saliva on dengue pathogenesis is still not well understood. inoculating mice lacking the interferon-α ... | 2016 | 27310141 |
| perceived risk of dengue in ones' living environment as a determinant of behavior change through social mobilization and communication: evidence from a high risk area in sri lanka. | the aim of this study was to assess community knowledge and behavioral impact of the social mobilization and communication strategy applied in a dengue high-risk area in sri lanka. | 2016 | 27308297 |
| behavioral response of aedes aegypti mosquito towards essential oils using olfactometer. | aedes aegypti mosquito is responsible for transmitting human diseases like dengue and chikungunya. personal or space protection with insect repellents is a practical approach to reducing human mosquito contact, thereby minimizing disease transmission. essential oils are natural volatile substances from plants used as protective measure against blood-sucking mosquitoes. | 2016 | 27308295 |
| screening of methanolic plant extracts against larvae of aedes aegypti and anopheles stephensi in mysore. | mosquitoes transmit serious human diseases, causing millions of death every year. vector control is facing a threat due to the emergence of resistance to synthetic insecticides. insecticides of botanical origin may serve as suitable alternative biocontrol techniques in the future. nine different locally available medicinally important plants suspected to posse larvicidal property were screened against fourth instar larvae of aedes aegypti and anopheles stephensi to a series of concentrations of ... | 2016 | 27308289 |
| odonate nymphs: generalist predators and their potential in the management of dengue mosquito, aedes aegypti (diptera: culicidae). | dengue is amongst the most serious mosquito-borne infectious disease with hot spots in tropical and subtropical parts of the world. unfortunately, no licensed vaccine for the disease is currently available in medicine markets. the only option available is the management of dengue vector mosquito, aedes aegypti (diptera: culicidae). | 2016 | 27308283 |
| genetic drift, purifying selection and vector genotype shape dengue virus intra-host genetic diversity in mosquitoes. | due to their error-prone replication, rna viruses typically exist as a diverse population of closely related genomes, which is considered critical for their fitness and adaptive potential. intra-host demographic fluctuations that stochastically reduce the effective size of viral populations are a challenge to maintaining genetic diversity during systemic host infection. arthropod-borne viruses (arboviruses) traverse several anatomical barriers during infection of their arthropod vectors that are ... | 2016 | 27304978 |
| discovery of point mutations in the voltage-gated sodium channel from african aedes aegypti populations: potential phylogenetic reasons for gene introgression. | yellow fever is endemic in some countries in africa, and aedes aegpyti is one of the most important vectors implicated in the outbreak. the mapping of the nation-wide distribution and the detection of insecticide resistance of vector mosquitoes will provide the beneficial information for forecasting of dengue and yellow fever outbreaks and effective control measures. | 2016 | 27304430 |
| potential risk of dengue and chikungunya outbreaks in northern italy based on a population model of aedes albopictus (diptera: culicidae). | the rapid invasion and spread of aedes albopictus (skuse, 1894) within new continents and climatic ranges has created favorable conditions for the emergence of tropical arboviral diseases in the invaded areas. we used mosquito abundance data from 2014 collected across ten sites in northern italy to calibrate a population model for aedes albopictus and estimate the potential of imported human cases of chikungunya or dengue to generate the condition for their autochthonous transmission in the abse ... | 2016 | 27304211 |
| zika is not a reason for missing the olympic games in rio de janeiro: response to the open letter of dr attaran and colleagues to dr margaret chan, director - general, who, on the zika threat to the olympic and paralympic games. | attaran and colleagues in an open letter to who expressed their concern about the upcoming olympic and paralympic games in rio de janeiro and the threat posed by the zika epidemic (attaran 2016). we agree that zika virus is of great public health concern and much remains to be known about this disease. care should be taken to reduce the risk of infection, especially to pregnant women. however, we argue that this is not sufficient reason for changing the original plans for the games, in particula ... | 0 | 27304097 |
| the threat of zika virus in sub-saharan africa - the need to remain vigilant. | 2016 | 27303663 | |
| [hemorrhagic form of dengue fever observed at the infectious diseases department chu yalgado ouédraogo, burkina faso]. | dengue is a re-emerging arboviral disease in tropical countries. haemorrhagic form may be associated with circulatory failure and produce hypovolemic shock, which is often fatal. we report a series of three cases of hemorrhagic dengue observed at the infectious diseases department chu yalgado ouédraogo, ouagadougou, in order to describe its epidemiological, clinical, and evolutive characteristics. our study included young females who had an onset age of between 35 years and 45 years, residing in ... | 2016 | 27303584 |
| a cd36 ectodomain mediates insect pheromone detection via a putative tunnelling mechanism. | cd36 transmembrane proteins have diverse roles in lipid uptake, cell adhesion and pathogen sensing. despite numerous in vitro studies, how they act in native cellular contexts is poorly understood. a drosophila cd36 homologue, sensory neuron membrane protein 1 (snmp1), was previously shown to facilitate detection of lipid-derived pheromones by their cognate receptors in olfactory cilia. here we investigate how snmp1 functions in vivo. structure-activity dissection demonstrates that snmp1's ectod ... | 2016 | 27302750 |
| virus-like particles derived from pichia pastoris-expressed dengue virus type 1 glycoprotein elicit homotypic virus-neutralizing envelope domain iii-directed antibodies. | four antigenically distinct serotypes (1-4) of dengue viruses (denvs) cause dengue disease. antibodies to any one denv serotype have the potential to predispose an individual to more severe disease upon infection with a different denv serotype. a dengue vaccine must elicit homotypic neutralizing antibodies to all four denv serotypes to avoid the risk of such antibody-dependent enhancement in the vaccine recipient. this is a formidable challenge as evident from the lack of protective efficacy aga ... | 2016 | 27301568 |
| prospects and challenges of crispr/cas genome editing for the study and control of neglected vector-borne nematode diseases. | neglected tropical diseases caused by parasitic nematodes inflict an immense health and socioeconomic burden throughout much of the developing world. current estimates indicate that more than two billion people are infected with nematodes, resulting in the loss of 14 million disability-adjusted life years per annum. although these parasites cause significant mortality, they primarily cause chronic morbidity through a wide range of severe clinical ailments. treatment options for nematode infectio ... | 2016 | 27300487 |
| [zika virus and zika viral disease]. | since zika virus (zikv) has firstly been isolated in 1947, uganda, outbreaks of zika fever have been reported in many areas such as in africa, southeast asia and america. imported cases in china also have been reported. zika virus belongs to the family flaviviridae, genus flavivirus, and include africa subtype and asia subtype. it is a mosquito-borne virus primarily transmitted by aedes aegypti mosquitoes. sexual transmission, blood transmission and mother-to-fetus transmission were also reporte ... | 2016 | 27295893 |
| alphavirus infection: host cell shut-off and inhibition of antiviral responses. | alphaviruses cause debilitating disease in humans and animals and are transmitted by blood-feeding arthropods, typically mosquitoes. with a traditional focus on two models, sindbis virus and semliki forest virus, alphavirus research has significantly intensified in the last decade partly due to the re-emergence and dramatic expansion of chikungunya virus in asia, europe, and the americas. as a consequence, alphavirus-host interactions are now understood in much more molecular detail, and importa ... | 2016 | 27294951 |
| antiviral hammerhead ribozymes are effective for developing transgenic suppression of chikungunya virus in aedes aegypti mosquitoes. | the chikungunya virus (chikv) is an emerging pathogen with widespread distribution in regions of africa, india, and asia that threatens to spread into temperate climates with the introduction of its major vector, aedes albopictus. chikv causes a disease frequently misdiagnosed as dengue fever, with potentially life-threatening symptoms that can result in a longer-term debilitating arthritis. the increasing risk of spread from endemic regions via human travel and commerce and the current absence ... | 2016 | 27294950 |
| toxicological assessment of spinosad: implications for integrated control of aedes aegypti using larvicides and larvivorous fish. | integration of larvivorous fish and biolarvicides at low concentrations to control of mosquito larvae in field situations may result in a safer and more effective tool. however, the usefulness of integrated approach depends upon survival and ecological fitness of fish employed. thus, the aim of this study was to examine the genotoxic effects of combining different sublethal concentrations of spinosad, a naturally occurring neurotoxic insecticide, with male adult poecilid larvivorous guppy (poeci ... | 2016 | 27294296 |
| antinociceptive effect of tephrosia sinapou extract in the acetic acid, phenyl-p-benzoquinone, formalin, and complete freund's adjuvant models of overt pain-like behavior in mice. | tephrosia toxicaria, which is currently known as tephrosia sinapou (buc'hoz) a. chev. (fabaceae), is a source of compounds such as flavonoids. t. sinapou has been used in amazonian countries traditional medicine to alleviate pain and inflammation. the purpose of this study was to evaluate the analgesic effects of t. sinapou ethyl acetate extract in overt pain-like behavior models in mice by using writhing response and flinching/licking tests. we demonstrated in this study that t. sinapou extract ... | 2016 | 27293981 |
| gene family evolution reflects adaptation to soil environmental stressors in the genome of the collembolan orchesella cincta. | collembola (springtails) are detritivorous hexapods that inhabit the soil and its litter layer. the ecology of the springtail orchesella cincta is extensively studied in the context of adaptation to anthropogenically disturbed areas. here, we present a draft genome of an o. cincta reference strain with an estimated size of 286.8 mbp, containing 20,249 genes. in total, 446 gene families are expanded and 1,169 gene families evolved specific to this lineage. besides these gene families involved in ... | 2016 | 27289101 |
| effects of preexposure to deet on the downstream blood-feeding behaviors of aedes aegypti (diptera: culicidae) mosquitoes. | mosquito behavior is heavily influenced by the chemical molecules in the environment. this knowledge can be used to modify insect behaviors; particularly to reduce vector-host contact as a powerful method for disease prevention. n,n-diethyl-meta-toluamide (deet) is the most widely used insect repellent in the market and an excellent example of a chemical that has been used to modify insect behavior for disease prevention. however, genetic insensitivity and habituation in aedes aegypti (l.) mosqu ... | 2016 | 27288690 |
| somatostatin signaling system as an ancestral mechanism: myoregulatory activity of an allatostatin-c peptide in hydra. | the coordination of physiological processes requires precise communication between cells. cellular interactions allow cells to be functionally related, facilitating the maintaining of homeostasis. neuropeptides functioning as intercellular signals are widely distributed in metazoa. it is assumed that neuropeptides were the first intercellular transmitters, appearing early during the evolution. in cnidarians, neuropeptides are mainly involved in neurotransmission, acting directly or indirectly on ... | 2016 | 27288244 |
| chemical composition and biological activity of essential oils from different species of piper from panama. | the chemical composition of leaf essential oils from 11 species of piper from panama was analyzed by a combination gc-fid and gc-ms procedures. six of them had sesquiterpene hydrocarbons as major constituents, three were characterized by monoterpene hydrocarbons, one by a diterpene, and one by a phenylpropanoid, dillapiole. the main components identified in each species were: cembratrienol (25.4 %) in piper augustum; β-pinene (26.6 %) in piper corrugatum; α-pinene (19.4 %) in piper curtispicum; ... | 2016 | 27286333 |
| zika: what we do and do not know based on the experiences of brazil. | zika virus, which was first discovered in 1947, has become a global threat to human health as it is rapidly spreading through latin america, the caribbean, the us and asia, after causing a large outbreak in the northeast region of brazil in 2015. there is ample evidence to support that zika virus is associated with neurological complications such as microcephaly. the review aims to provide an overview on the complex issues involved in the emergence of zika virus's neurological disorders and to d ... | 2016 | 27283140 |
| reported distribution of aedes (stegomyia) aegypti and aedes (stegomyia) albopictus in the united states, 1995-2016 (diptera: culicidae). | aedes (stegomyia) aegypti (l.) and aedes (stegomyia) albopictus (skuse) transmit arboviruses that are increasing threats to human health in the americas, particularly dengue, chikungunya, and zika viruses. epidemics of the associated arboviral diseases have been limited to south and central america, mexico, and the caribbean in the western hemisphere, with only minor localized outbreaks in the united states. nevertheless, accurate and up-to-date information for the geographical ranges of ae. aeg ... | 2016 | 27282817 |
| evidence for natural vertical transmission of chikungunya viruses in field populations of aedes aegypti in delhi and haryana states in india-a preliminary report. | aedes aegypti and aedes albopictus are principal vectors for the transmission of chikungunya virus (chikv). india is a hub for both dengue and chikungunya infections and there are several reports of co-infection of dengue and chikungunya virus in the clinical scenario. the present pilot entomological survey was conducted to evaluate vertical transmission of chikv in aedes field populations. aedes immature (larvae and pupae) collection was done in 2012, over a period of six months from selected s ... | 2016 | 27282096 |
| dengue vaccine: considerations before rollout in colombia. | 2016 | 27280803 | |
| semi-field evaluation of metofluthrin-impregnated nets on host-seeking aedes aegypti and anopheles dirus. | the efficacy of a metofluthrin-impregnated net (min) known as the "mushikonazu" on the house entry behavior of female aedes aegypti and anopheles dirus mosquitoes was evaluated using a semi-field 50-m tunnel setup. while the min is labeled for the control of chironomids and moth flies, this study determined the feasibility of using the device, given its current construction and metofluthrin formulation, as a spatial repellent against mosquitoes. sentinel and cone bioassays were used to determine ... | 2016 | 27280351 |
| new candidates for plant-based repellents against aedes aegypti. | based on an ethnobotanical study on use for plant species against mosquito bites in the kota tinggi district, johor state, malaysia, 3 plants selected for study, citrus aurantifolia (leaves), citrus grandis (fruit peel), and alpinia galanga (rhizome), were extracted using hydrodistillation to produce essential oils. these essential oils were then formulated as a lotion using a microencapsulation process and then tested for their repellent effect against aedes aegypti. n,n-diethyl-m-toluamide (de ... | 2016 | 27280349 |
| insights into sexual precocity of female oriental river prawn macrobrachium nipponense through transcriptome analysis. | the oriental river prawn (macrobrachium nipponense) is the most prevalent aquaculture species in china. the sexual precocity in this species has received considerable attention in recent years because more and more individuals matured at a small size, which devalues the commercial production. in this study, we developed deep-coverage transcriptomic sequencing data for the ovaries of sexually precocious and normal sexually mature m. nipponense using next-generation rna sequencing technology and a ... | 2016 | 27280288 |
| zika virus, elevation, and transmission risk. | zika virus has appeared in the americas in the form of a major outbreak, and is now known to cause birth defects when pregnant women are infected. as a result, the centers for disease control and prevention issued travel guidelines, in the form of an elevational risk definition: destinations below 2000m are considered as at-risk. | 2016 | 27280061 |
| toxicity of boswellia dalzielii (burseraceae) leaf fractions against immature stages of anopheles gambiae (giles) and culex quinquefasciatus (say) (diptera: culicidae). | mosquitoes are vectors of several human pathogens, and great attention has recently been placed on insecticides from plant-derived products, in search for mosquito control agents. this study, thus, investigated the potency of boswellia dalzielii methanol leaf extract and its four fractions as mosquito ovicide, larvicide, and pupicide against anopheles gambiae and culex quinquefasciatus. the plant products were tested at the following concentrations: 125, 250, 500, 1000, and 2000 ppm on eggs and ... | 2016 | 27279752 |
| mass spectrometry analysis and transcriptome sequencing reveal glowing squid crystal proteins are in the same superfamily as firefly luciferase. | the japanese firefly squid hotaru-ika (watasenia scintillans) produces intense blue light from photophores at the tips of two arms. these photophores are densely packed with protein microcrystals that catalyse the bioluminescent reaction using atp and the substrate coelenterazine disulfate. the squid is the only organism known to produce light using protein crystals. we extracted microcrystals from arm tip photophores and identified the constituent proteins using mass spectrometry and transcript ... | 2016 | 27279452 |
| the brazilian zika virus strain causes birth defects in experimental models. | zika virus (zikv) is an arbovirus belonging to the genus flavivirus (family flaviviridae) and was first described in 1947 in uganda following blood analyses of sentinel rhesus monkeys. until the twentieth century, the african and asian lineages of the virus did not cause meaningful infections in humans. however, in 2007, vectored by aedes aegypti mosquitoes, zikv caused the first noteworthy epidemic on the yap island in micronesia. patients experienced fever, skin rash, arthralgia and conjunctiv ... | 0 | 27279226 |
| nucleotide composition of the zika virus rna genome and its codon usage. | rna viruses have genomes with a distinct nucleotide composition and codon usage. we present the global characteristics of the rna genome of zika virus (zikv), an emerging pathogen within the flavivirus genus. zikv was first isolated in 1947 in uganda, caused a widespread epidemic in south and central america and the caribbean in 2015 and has recently been associated with microcephaly in newborns. | 2016 | 27278486 |