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immunology and the anaesthetist. 20103768621
genetic variations in blood proteins within and between spanish dairy sheep breeds.eleven flocks of three spanish sheep breeds have been studied: four churra, four lacha and three manchega. genetic variations between flocks of the same and different breeds have been analysed, using eight genetic blood systems and a wide range of statistical methods. the results show that the churra, lacha and manchega breeds present significant differences between each other. significant intraracial variations have been observed in churras and lachas, although they were almost non-existent in ...19863767081
hypomyelination neuropathy in a female newborn presenting as arthrogryposis multiplex congenita.a female newborn delivered at 32 weeks of gestation presented with multiple joint contractures consistent with arthrogryposis multiplex congenita (amc). the girl died after a four days course of severe respiratory distress. autopsy revealed slightly hypoplastic and immature lungs with acute necrotizing bronchopneumonia, and marked consecutive hypoxic brain lesions with severe periventricular haemorrhages. the peripheral nerves including the cranial and spinal nerve roots showed a hypomyelination ...20133762869
psychoanalysis and time.psychoanalysis is fundamentally related to time because it is an effort to understand how disturbances in the present are determined by events in the past. technically, we know that the patient who is reporting immediate perceptions is not aware of the passage of time, but he becomes self-conscious as undesirable elements threaten to appear in his associations. time is not sensed by direct awareness, nor is it an agent of action or events. various functions of the ego influence how time is exper ...19863760442
prevalence of toxoplasma antibodies in southern louisiana swine.sera from 1,219 pigs slaughtered in acadian louisiana in 1980 and 1981 were tested using the indirect hemagglutination test and microtiter system for toxoplasma antibodies and 19.2% had titers of 1:64 or higher. pigs slaughtered in the colder months, november to march, had significantly higher seroprevalences than pigs slaughtered in the warmer months. 24.6% of 236 farm bled sows and gilts had similarly high titers.19863759353
[a ten year survey of diagnosis, treatment and follow-up of cancer of the colon in a regional hospital]. 20133758859
effect of shigella toxin on preimplantation mouse embryos in vitro.preimplantation mouse embryos at the 4-cell to 8-cell stage were exposed to shigella dysenteriae toxin at concentrations of 0.001-100 pg/ml in vitro. the effect of the toxin was studied by morphological observation of the embryos to the blastocyst stage, by assessing protein synthesis with 14c-leucine incorporation, and by measuring embryonic adenosine triphosphate (atp) content. preimplantation mouse embryos were highly sensitive to the toxin. all variables investigated were adversely influence ...19863755556
[computer-assisted preliminary determination of the refraction of intraocular lenses].seventy-seven cases with posterior chamber lenses were examined after suture removal. the residual astigmatism measured 1.27 d. the remaining refraction (spheric equivalent) was 1.6 d. the relation in size of the two corresponding retina images (isoiconia) was taken into consideration by prior determination of lens power based on computerized measurement. the computer program was developed by lepper (bonn). the method of lens power calculation is described.20083755189
[program for computing cardiac hemodynamics on the elektronika bz-21 program-controlled computer]. 20133754673
current management of the totally disabled ear. 20133754300
1,25-dihydroxyvitamin d3 treatment results in increased choline acetyltransferase activity in specific brain nuclei.to better understand the role of 1,25-dihydroxyvitamin d3 [1,25-(oh)2d3] in brain function, the level of calcium-binding protein (cabp) and the activities of choline acetyltransferase (cat) and monoamine oxidase were measured in discrete brain nuclei of vitamin d-deficient and -replete male rats. the nuclei sampled were those in which receptors for 1,25-(oh)2d3 and/or vitamin d-dependent cabp have been localized. significant elevations in cat activity were found in the arcuatemedian eminence and ...19863753932
[educational development of so-called problem children]. 20133751740
pulmonary aspergillosis in immunosuppressed patients with haematological malignancies.invasive pulmonary aspergillosis as a cause of mortality and morbidity in patients with haematological malignancies is becoming more common. predisposing factors are powerful immunosuppressive chemotherapy, neutropenia and synergistic combinations of antibiotics of great potency and wide spectrum of activity. clinical and radiological signs are heterogeneous, sometimes misleading and often absent. treatment is often empirical on suspicion alone. amphotericin b is the only effective drug but it h ...20093749452
[systemic mechanisms of development and compensation of acute hypoxemia in experimental methemoglobinemia in dogs]. 19863748626
[radiation biology risk of imaging procedures].the environmental radiation burden of man in germany is about 1 mgy (milligray) per year. this is, of course, also valid for children. due to diagnostical procedures this burden is increased to about 1.3 mgy. the question arises wether this can be neglected, or important consequences have to be drawn. to give a clear answer, the action of ionizing radiation in living cells and in organisms is explained in detail. many of the radiation actions at the dna can soon be repaired by the cell, if the r ...19863748028
synaptic and golgi membrane recycling in cochlear hair cells.membrane recycling in the mechanoreceptive sensory cells of the mammalian cochlea was studied by observing membrane-bound horseradish peroxidase (hrp) reaction product following brief in vivo exposure to the enzyme. in the inner hair cell (ihc), peroxidase was taken up into coated vesicles and became incorporated into synaptic vesicles surrounding presynaptic bodies, but much hrp was also transported to the apical zone where reaction product appeared in all components of the golgi complex. neith ...19863746347
5 alpha reductase deficiency causing male pseudohermaphroditism. 20133744510
his needs place tough demands on dp directors. 20133744360
fibromuscular dysplasia of the internal carotid artery.an observation on symptomatic fibromuscular dysplasia of the internal carotid artery, surgically treated by graduated internal dilatation is presented. fibromuscular dysplasia is a segmental, nonatheromatous disease of small to medium-sized arteries, affecting mainly renal arteries. involvement of the internal carotid artery is often an incidental angiographic finding in asymptomatic patients, but can be associated with specific neurologic symptoms requiring surgical treatment. the histopatholog ...20133739510
[mechanism of hyperdynamic systemic circulation in cirrhotic patients]. 20133735731
structure and x-ray amino acid sequence of a bacteriochlorophyll a protein from prosthecochloris aestuarii refined at 1.9 a resolution.the structure of the water-soluble bacteriochlorophyll a protein (bchl protein) from the green photosynthetic bacterium prosthecochloris aestuarii has been refined at 1.9 a resolution to a crystallographic residual of 18.9%. the refinement was carried out without knowledge of the amino acid sequence and has led to an "x-ray sequence". the structure consists of seven bchl molecules enclosed within a protein "bag" and the refinement supports the general conformation of the molecule described previ ...19863735428
postgraduate general practice training in the united kingdom. 20133734723
[esophageal scintigraphy and ph measurement in asthmatic adults suspected of having gastroesophageal reflux].fifty-five adults with asthma were explored by gastroesophageal scintigraphy (ges) and ph monitoring (3 postprandial hours, 12 nocturnal hours). for their asthma, all patients received theophylline twice a day. associated digestive symptomatology led to investigations for gastroesophageal reflux (ger). twelve hours ph monitoring, the reference method, was validated in 13 normal volunteers. during 12 hr ph monitoring, 4 criteria were studied: number of ger, percentage of time at ph 4, number of g ...20123732745
cosinor demonstration of circatrigintan (circavigintan) biorhythm in cell component volume of female urethral ejaculate.in urethral expulsions of a multipara, aged 37 years, induced by digital stimulation over a time span of almost one and a half 26-day menstrual cycle, the volume of desquamated cellular component changed, according to two nearly identical versions of cosinor, with the period of 22-27 days, with the acrophase between 17th and 23rd day of menstrual cycle and with the amplitude between 0.5 and 1.2 ml/day. the issue testifies to periodic quantitative changes in squamous cells of vaginal type in fema ...20123731948
[prevention of ischemic and re-oxygenation arrhythmias and heart fibrillation using the antioxidant ionol].the effect of a synthetic antioxidant, ionol (2,4-ditrebutyl-4-methylphenol) on cardiac arrhythmias induced by 10-minute occlusion of the left coronary artery followed by 5 minutes of reperfusion (rp) was investigated. the study was performed on male wistar rats, 250-300 g body weight. the animals were ventilated with room air under urethan anesthesia. rp induced more severe ventricular arrhythmias than ischemia (is). during rp ventricular fibrillation developed in 12 and during is in 2 out of 2 ...19863730544
[prevention of ischemic and re-oxygenation arrhythmias and heart fibrillation using the antioxidant ionol].the effect of a synthetic antioxidant, ionol (2,4-ditrebutyl-4-methylphenol) on cardiac arrhythmias induced by 10-minute occlusion of the left coronary artery followed by 5 minutes of reperfusion (rp) was investigated. the study was performed on male wistar rats, 250-300 g body weight. the animals were ventilated with room air under urethan anesthesia. rp induced more severe ventricular arrhythmias than ischemia (is). during rp ventricular fibrillation developed in 12 and during is in 2 out of 2 ...19863730544
covert splenic abscess: a continuing challenge.although splenic abscess is a rare cause of intra-abdominal sepsis, the mortality rate remains high especially in patients with silent or covert lesions. the clinical presentation and course of five patients with overt splenic abscess and seven patients with covert splenic abscess seen during a thirty year period were analyzed. average age of patients with overt lesions was 44.5 years. direct extension from a contiguous source, hematogenous spread from a distant site (metastatic) and trauma comp ...20133729173
multimodal evoked responses and cerebrospinal fluid oligoclonal immunoglobulins in patients with multiple sclerosis.one hundred patients with possible, probable and definite multiple sclerosis (ms) were examined with somatosensory (ser), visual (ver) and brain stem auditory (baer) evoked responses. paired samples of cerebrospinal fluid (csf) and serum were examined with agarose gel electrophoresis to detect intrathecally synthesized oligoclonal immunoglobin bands. comparison of the number of abnormal csf and evoked response tests showed that the csf examination was slightly more sensitive in all diagnostic gr ...20133727924
another dimension for informed consent. 20133725943
bacterial infections of the orbital and periorbital soft-tissues in children.periorbital soft-tissue bacterial infections are relatively common during childhood and with appropriate antimicrobial therapy usually resolve quickly. orbital soft-tissue infections, in contrast, are rare and frequently cause serious morbidity. two hundred forty-one children with periorbital or orbital soft-tissue infections have been hospitalized since 1962 and constitute the data base for this study. two hundred twenty-six children, half under 1 year of age, had periorbital soft-tissue infect ...20123724328
morphogenesis of sclerotome and neural crest in avian embryos. in vivo and in vitro studies on the role of notochordal extracellular material.the distribution of sclerotome and neural crest cells of avian embryos was studied by light and electron microscopy. sclerotome cells radiated from the somites towards the notochord, to occupy the perichordal space. neural crest cells, at least initially, also entered cell-free spaces. at the cranial somitic levels they moved chiefly dorsal to the somites, favouring the rostral part of each somite. these cells did not approach the perichordal space. more caudally (i.e. trunk levels), neural cres ...19863719666
[granulocyte alloimmunization during hemotherapy]. 20133719627
initial management of cutaneous malignant melanoma.appropriate initial surgical management of primary cutaneous malignant melanoma is important since no effective treatment exists once the tumour metastasizes. the author reviews methods of initial treatment, excisional biopsy with adequate margins being the most common. he also reports results from a questionnaire survey on the type of microstaging used at hospitals across canada. two thirds of the pathologists who responded to the questionnaire preferred to use both clark's and breslow's method ...20133719498
offspring-parent genotypic regression: how linear is it?linearity of offspring-parent regression is investigated for quantitative characters with dominance. this is done by fitting a second-order regression equation in orthogonal bivariate polynomials to the offspring's genotypic value and evaluating the significance of nonlinear terms in the equation. three genetic models are considered.20133719063
letters concerning hr 1309, "the high risk occupational disease notification and prevention act of 1985". 20133717004
triethyltin-induced neuronal damage in neonatally exposed rats.neuropathological and biochemical effects of neonatal exposure to the alkyl metal triethyltin were examined in juvenile male long evans rats. rats were injected intraperitoneally on postnatal day 5 with 6 mg/kg of triethyltin bromide and sampled on day 20. the brains of tin-treated animals weighed significantly less than either saline or starved controls and exhibited a marked caviation of the ventrolateral surfaces. histologically, neuronal necrosis was noted in the entorhinal and transitional ...19863714127
[evaluation of cerebral ischemia during carotid thromboendarterectomy operations]. 20123714067
[risk factors in selective proximal vagotomy]. 20133713051
[pathology of shock accompanying endoscopic embolization of esophageal varices using thrombin]. 20133712779
smoking behavior and participation in organized exercise. 20133708500
increased collateralization of the cerebellothalamic pathway following neonatal hemicerebellectomy.the postlesional reorganization of the cerebellothalamic cells was here studied using a multiple retrograde tracing technique. to this purpose, the cerebellothalamic cell population was investigated in 3 groups of adult rats: (a) cases hemicerebellectomized at birth; (b) cases hemicerebellectomized in adulthood; and (c) control unlesioned ones. in all of the groups the fluorescent tracers diamidino yellow and fast blue were injected bilaterally in the thalamus and the retrograde labeling obtaine ...19863708349
somatotopic organization of motoneurons innervating the pronators, carpal and digital flexors and forepaw muscles in the dog: a retrograde horseradish peroxidase study.central distribution of motor neurons innervating the individual forearm and forepaw muscle through the median and ulnar nerves was studied in the dog using the retrograde horseradish peroxidase (hrp) method. all hrp-labeled cells were seen ipsilaterally in restricted parts within the dorsolateral (dl) and retrodorsolateral nucleus (rdl) of the ventral horn at levels from the cranial tip of c7 to the cranial third of t2. the results showed that motoneurons situated more cranially supply the more ...19863708348
[value of computerized axial tomography in the diagnosis of idiopathic retroperitoneal fibrosis. apropos of 2 new cases]. 20133707209
[cytogenetic activity of metabolites of pesticides representing different classes of chemical compounds].the cytogenetic activity of some substances formed in agricultural plants during metabolism of pesticides of four classes of chemical compounds was studied in the culture of human peripheric blood lymphocytes. metabolites were shown either to have mutagenic properties similar to those of the initial compounds (ziramtetramethylthiourea, both being mutagens; captan-phthalimide, both possessing no cytogenetic activity) or to be considerably transformed in comparison with them as a result of deactiv ...19863705167
[the empty delta sign. a useful or misleading sign in cerebral x-ray computed tomography?].one case of bifidity of the superior sagittal sinus, resulting in a false "empty delta sign", is presented. the authors emphasize the importance of the indirect signs of sinovenous thrombosis, i.e. cerebral edema and multiple or bilateral hemorrhagic infarcts, in the diagnosis of true empty delta sign.20133701671
steroid receptors in uterine cervical cancers.in cervical cancers, the estrogen receptor (er) and progestin receptor (pr) were characterized in the cytosol protein. receptor levels were determined in cytosol, nuclear kcl extract, and nuclear kcl unextractable fraction in various cervical cancer tissues. the androgen receptor (ar) was also similarly characterized. in the cytosol, the estrogen (e2)-er complex and the promegesterone (r5020)-pr complex were sedimented at approximately the 5s and 8s or the 4s and 8s regions, respectively, by 5-2 ...20133701146
copper treatment of the digestive gland of the slug arion ater l. 2. morphometrics and histophysiology. 20133697536
starch granuloma: the problems caused by surgical glove powder. 20133696223
monitoring intervals between rare events: a cumulative score procedure compared with rina chen's sets technique. 20133695978
laryngeal trauma vs length of intubation.the frequency histograms of six patients' laryngographs were studied pre- and post-endotracheal intubation. the changes were correlated with the length of intubation. the post-operative hoarse voice was seen as an increase in the spread of the lower frequencies, and an increase in the fundamental frequency. the latter change was thought to be a subconscious compensation for the hoarseness. the increased lower frequency spread as measured by standard deviation was directly proportional to the len ...20133694032
[change in tissue glycogen reserves in tumor bearers as a reflection of a hypoglycemic stress syndrome].glycogen content in the brain, liver and skeletal muscles of rats bearing ascite zajdela hepatoma (azh) and solid 27 hepatoma (27-h) has been studied. serum glucose levels directly correlated with liver glycogen reserves. in the terminal stage of tumor growth depletion of liver glycogen was observed, while the stores of muscle glycogen did not diminish. within 1-4 days (azh) and 15-30 days (27-h) after implantation the stores even exceeded those of control healthy rats. in the terminal stage, in ...19873689968
decisions relating to alcohol-impaired driving: an exploratory analysis.this paper focuses on an individual's decision to drive or not to drive after drinking. to evaluate this decision, a utility maximizing probabilistic choice model is specified and estimated using a sample of college students. the estimation results provide interesting insights relating to the potential effectiveness of drinking-driving countermeasures, and suggest that the most effective methods of reducing the probability of driving after drinking are those advertising and awareness campaigns t ...20133689555
ultrasonically induced gas bubble production in agar based gels: part i. experimental investigation.macroscopically visible gas bubbles can be produced in an agar based gel by irradiation with either continuous or pulsed ultrasound at frequencies from 0.75 to 3.0 mhz. the variation in the number of bubbles formed with frequency, acoustic pressure, pulse length, duty cycle, and temperature closely resembles that seen in vivo. furthermore, the acoustic pressure required to initiate bubble formation is also close to that required in vivo. it has been observed that alterations in the concentration ...20133686733
[the veins of the heart. ii. functional anatomy of the coronary sinus and its implications in pathology]. 20133685706
[proceedings. the international congress of the italian section of the international college of surgeons and the 4th national seminar on technics in surgery. cortina d'ampezzo, 30 january-1 february 1986]. 20133683901
intra-right-atrial balloon pumping (irabp) during a fontan procedure. 19873676005
efficacy of propranolol therapy after acute myocardial infarction related to coronary arterial anatomy and left ventricular function.the effect of the beta-adrenergic blocking agent propranolol on morbidity and mortality risk after acute myocardial infarction was studied relative to coronary anatomy and left ventricular (lv) ejection fraction in a subset of 406 patients participating in a randomized study of 3,837 patients in the beta blocker heart attack trial (bhat). median follow-up for this subset of patients was 28 months. the mortality rate was 2% (2 of 100) in patients with 2- and 3-vessel coronary artery disease takin ...20133673915
surgical management of patients with hyperhidrosis.eighteen patients with hyperhidrosis affecting different anatomical areas were treated with a variety of surgical methods. bilateral axillary gland excision is an appropriate and cosmetically acceptable method of treating axillary hyperhidrosis (11 patients). bilateral supraclavicular cervical sympathectomy was performed for excessive sweating of the hands (7 patients). bilateral lumbar sympathectomy was necessary in only 3 patients with excessive sweating of the feet. when perineal hyperhidrosi ...20133672271
leukemoid reaction in shigella dysenteriae type 1 infection. 19873666850
the mode of action of shiga toxin on peptide elongation of eukaryotic protein synthesis.the effect of shiga toxin, from shigella dysenteriae 1, on the component reactions of peptide elongation were investigated. enzymic binding of [3h]phenylalanine-trna to reticulocyte ribosomes was inhibited by 50% at 7 nm toxin. elongation factor 1 (eef-1)-dependent gtpase activity was also inhibited. both reactions were not restored by addition of excess eef-1 protein. in contrast, toxin concentrations of 200 nm were required to inhibit by 50% the elongation factor 2 (eef-2)-dependent translocat ...19873663122
modulation of melanoma-associated antigens by monoclonal antibodies as visualized by radioimmunoelectron microscopy and radioantibody binding assay.there is a wealth of information about monoclonal antibody (mab) specificity and function on fixed tissues, yet little is known about formation and release of antigen-antibody complexes and their functional behavior in vivo. we analyzed the pathway of radiolabeled mabs directed against melanoma-associated antigens by radioimmunoelectron microscopy (riem) on metabolically active cells of the melanoma cell lines sk-mel-28, mewo and colo 38 at different time intervals. in parallel, binding and rele ...20133662602
effect of different fractions of dialyzable leukocyte extract--transfer factor--on the chemiluminescence of human phagocytes.the chemiluminescence (cl) inducing effect of the fractions of dialyzable leukocyte extract (dle)--transfer factor--from tonsil leukocytes was tested on the phagocytes of human whole blood. the fractionation of dle by sephadex g-25 results in three main fractions: i, ii, iii. we found only fraction ii having a direct cl inducing effect on the non-stimulated cells. fraction ii increased further the cl of phagocytes which were stimulated by zymosan (mannozym). fractions i and iii were ineffective. ...19873661353
hla-a,b,c and dr antigens in a sample of the tunisian population.the hla-a, b and dr phenotypes of 109 unrelated tunisian individuals have been determined. the hla-a and b antigen frequencies were compared with data reported for european caucasoids and various arab populations. most similarities in antigen frequencies were seen between tunisians and kabyles from north africa. a high frequency of hla-a23 and hla-bw50 was observed in tunisians and all arab populations. a very close similarity in hla-dr antigen frequencies exists between tunisians and european c ...20133660397
[reconstructive plastic surgery of the humeral condyles following removal of endoprostheses of the elbow versus arthrodesis].the condyles of the elbow are of utmost importance for the stability of this joint. this is particularly evident in cases where elbow prostheses had to be removed because of loosening or infection and where the condyles had been deliberately resected at the primary operation. in order to obtain a functional elbow with sufficient stability and mobility after removal of the prostheses, we can reconstruct the condyles by means of a large autologous bone graft, which we take from the midpart of the ...20133658417
immunoglobulin-gene rearrangement in benign lymphoepithelial lesions. 20133657883
the ec-ic bypass study. 20133657863
[status of muscle blood flow in the lower extremities in arteriosclerosis obliterans in middle-aged and elderly patients]. 20133656950
photoperiodic modification of negative and positive feedback effects of oestradiol on lh secretion in ovariectomized goats.ovariectomized shiba goats carrying an oestradiol implant (4-10 pg/ml) were kept under a short-day light regimen (10l:14d; group 1, n = 4) or a long-day regimen (16l:8d; group 2, n = 4). plasma lh concentrations were lower (p less than 0.05) in group 2 than in group 1 between days 40 and 200, suggesting an enhanced negative feedback effect of oestradiol on lh secretion under a long-day regimen. on days 30, 60, 100, 149 and 279, an lh surge was induced by i.v. infusion of oestradiol for 48 h; the ...19873656284
isoperiodic bursting by magnocellular neuroendocrine cells in the rat hypothalamic slice.1. recruitment of magnocellular neuroendocrine cells (m.n.c.s) to a repetitive burst pattern (phasic firing) is associated with increased vasopressin secretion from neurohypophysial terminals in the intact animal. based on invertebrate studies, bursts of action potentials can arise in two distinct ways: as an intrinsic property of the recorded cell or as an emergent property of synaptic interactions. 2. the majority of phasic m.n.c.s in the hypothalamic slice preparation display an endogenous pa ...19873656153
[alternative treatment. anthroposophical medicine would create "balance"]. 20103645889
organizational positions on titling and entry into practice: a chronology. 20133642445
the cocaine epidemic: proof of the poison. 20133641046
[care of the elderly in new york city]. 20133639224
[practice of oriental medicine. 8. etiology and internal and external symptoms]. 20133639179
[norwegian nurses' association's need for adjustment negotiations--full support in counter-legal procedures against government]. 20133635987
review's report is 'a charter for nursing'. 20133634923
a fair deal for ens. 20013633116
altered shape and size of red blood cells in obese hyperglycaemic mice.red blood cells (rbcs) from hyperglycaemic ob/ob-mice, normoglycaemic controls, and a healthy man were sucked into a narrow capillary, photographed and measured. mouse rbcs had a smaller diameter than human ones. although of normal diameter, the ob/ob-mouse rbcs exhibited increased area and volume, and more frequently than control rbcs had a minimum cylindrical diameter greater that 3 micron. cross-sectional profiles with minimum bending resistance were computed for rbcs of mean area and volume. ...19873630732
ball thrombi in carotid artery plaque. 20123629659
mental health care. 20133622347
delayed sternal closure after cardiac surgery.fifty-seven patients undergoing various cardiac operations were managed with delayed sternal closure because of ongoing mediastinal hemorrhage or extreme cardiac dilatation. this strategy facilitated rapid access to the mediastinum for evacuation of clot when the risk of tamponade from hemorrhage was deemed great. when sternal closure over a dilated and edematous heart caused hemodynamically significant cardiac compression, wound closure without sternal reapproximation facilitated hemodynamic st ...20133619540
studies of populations at high risk for the future development of alcoholism.this paper has reviewed information on possible markers of a biological vulnerability towards alcoholism. most of the work is based on the premise that alcoholism is a genetically influenced disorder. the final development of alcoholism probably depends upon the interaction between biological and environmental influences. the emphasis placed on biology in this paper reflects both the discipline of the author and the probability that biological factors are easier to measure and, thus, more likely ...20133615529
myocardial dysfunction in sepsis.a synthesis of the postulated sequence of events for development of the inappropriate response of the myocardium to a demand for increased cardiac index is schematically represented in fig. 10. in sepsis, bacteremia and/or the release of endotoxin activate the macrophages which release a spectrum of mediators. some of these mediators (and possibly also endotoxin itself) have a negative influence on myocardial contractile function either directly and/or through altering cellular calcium flux. thi ...19873615452
myocardial dysfunction in sepsis.a synthesis of the postulated sequence of events for development of the inappropriate response of the myocardium to a demand for increased cardiac index is schematically represented in fig. 10. in sepsis, bacteremia and/or the release of endotoxin activate the macrophages which release a spectrum of mediators. some of these mediators (and possibly also endotoxin itself) have a negative influence on myocardial contractile function either directly and/or through altering cellular calcium flux. thi ...19873615452
[diagnosis of celiac disease]. 20083614409
thermally induced disulfide bond exchanges in human ige.the thermally induced changes in human ige was investigated using sodium dodecyl sulfate-polyacrylamide gel electrophoresis. when the ige (1 mg/ml) was heated at 56 degrees c for several hours in the absence of sodium dodecyl sulfate, it gave aggregated forms that could be reduced completely to heavy and light chains with dithiothreitol. on the other hand, in the presence of sodium dodecyl sulfate (0.1%), the ige was changed by heating to five components with small mol. wts dependent on temperat ...19873614214
pentapeptide nuclear localization signal in adenovirus e1a.the adenovirus e1a gene products are nuclear proteins important in transcriptional control of viral functions during infection. by producing normal e1a proteins and derivatives of e1a in bacteria and microinjecting these proteins into cultured cells, we were able to examine their ability to localize to the nucleus. we showed that a short peptide sequence at the carboxyl terminus of e1a is necessary for the rapid (30-min) nuclear localization of that protein. additionally, we showed that just the ...19873614197
[combined effects of fentanyl and diazepam on hemodynamics and myocardial blood flow in dogs with normal and ischemic heart]. 19873613053
a 15-year follow-up study of 512 consecutive charnley-muller total hip replacements.this article presents a prospective study of 512 consecutive total hip replacements done with the charnley-muller prosthesis. the operations were performed between 1967 and 1972. the follow-up period ranges from 13 1/2 to 18 years (average, 15 years). from the initial 512 replaced hips, only 148 were available for study at the end of 1985. the failure rate due to loosening of the prosthetic components, after a mean follow-up period of 15 years, was approximately 40%. the rate of loosening of the ...20133612141
results of fractional lengthening of the finger flexors in adults with upper extremity spasticity.flexor spasticity is common in the upper extremity after insult to the central nervous system. this leads to decreased function and hygiene problems as a result of the inability to extend the fingers. the results of fractional lengthening of the finger flexors of 27 patients with upper extremity flexor spasticity of the finger flexors were examined. patients were divided preoperatively into those with potentially functional hands and those who were nonfunctional based on the presence of motor co ...20123611656
accommodative hysteresis: influence on closed loop measures of far point and near point.the study examined accommodative hysteresis under closed loop viewing conditions. after sustained focus for 8 min at either the far-point (fp) or near-point (np) of accommodation, subjects exhibited hysteresis-like shifts in tonic accommodation, ie, dark focus (df), in the direction of the fixation target. measurement of np and fp before and after the focusing period showed that only the position of the np was significantly influenced, in a direction matching that of the df. the np shifted outwa ...20083610542
the changing demographic determinants of the growth of the extreme aged. 20133609794
[acoustic indicator of membrane potential levels]. 20133609385
[effect of anaprilin on the humoral and cellular immune response].the immunosuppressive effect of anaprilin on humoral and cellular responses was established during experiments on mice. the influence of the drug on the phenomenon of hypersensitivity of delayed type begins to be revealed at the lower dose of the drug (0.5 mg/kg) as compared with the inhibitory action of the beta-adrenoblocker on antibody formation (1 mg/kg).20123609279
[clinical competence and medical responsibility in rare cases]. 20123599673
tubal microsurgery. ii. experimental use.tubal microsurgery is a valuable tool to study tubal reproductive physiology and various infertility problems. microsurgical tubal resection reanastomoses of the rabbit fallopian tube and their impact on fertility are reviewed. data obtained from experimental work on the function of cilia and muscle activity in tubal transport are discussed.19873596349
reproductive mortality in the united states: recent trends and methodologic considerations.between 1975 and 1982, the annual number of deaths attributable to pregnancy and childbirth, induced abortion, and contraception in the united states declined from 1,083 to 751. the mortality rates for each of these components decreased by 35,89, and 35 per cent, respectively, and the overall reproductive mortality rate dropped by 35 per cent. the death rate due to pregnancy and childbirth is 25 times greater than that due to induced abortion and eight times more than that to contraceptive-assoc ...20133592037
cardiac-specific troponin-i radioimmunoassay in the diagnosis of acute myocardial infarction.the cardiac isotype of the myofibrillar contractile protein, troponin-i, is located specifically in the mammalian heart. a sensitive radioimmunoassay has been developed to detect human and nonhuman primate cardiac troponin-i in serum down to 10 ng/ml. immunochemical cross reactivity with skeletal troponin-i was only 2% and was species nonspecific. normal patient levels of cardiac troponin-i are about 10 ng/ml. in patients with acute myocardial infarction (n = 32), serum cardiac troponin-i was el ...19873591601
abdominosacral coloanostomy made by invagination.an abdominosacral 'closed' rectum resection is reported which, at the same time, enables the preparation of a provisional anal stoma for protection of the orifice.20123591175
abdominosacral coloanostomy made by invagination.an abdominosacral 'closed' rectum resection is reported which, at the same time, enables the preparation of a provisional anal stoma for protection of the orifice.20123591175
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