Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
|---|
| a conveyor belt task for assessing visuo-motor coordination in the marmoset (callithrix jacchus): effects of diazepam, chlorpromazine, pentobarbital and d-amphetamine. | a conveyor belt task for assessing visuo-motor coordination in the marmoset is described. animals are motivated by apple, a preferred food, under a state of minimal food deprivation. the apparatus used was designed to test animals within their home cages and not restrained in any way, thus avoiding possible confounding factors associated with restraint stress. stable baseline levels of performance were reached by all animals in a median of 24 sessions. performance was shown to be differentially ... | 1985 | 3927349 |
| plasmodium brasilianum in the common marmoset callithrix jacchus. | chronic quartan malarial infection has been established in the common marmoset (callithrix jacchus). plasmodium brasilianum from a douroucouli monkey (aotus trivirgatus) was used to infect splenectomized twin animals, passed to an intact animal, and then to 4 other intact adults, 2 pairs of twins. in 2 of the 4 latter animals there was continuing patency with parasitaemias of less than or equal to 0.5% parasitized erythrocytes for 30 weeks. the other 2 had lower initial levels of parasitaemia; i ... | 1985 | 3925423 |
| congenital malformations in a common marmoset (callithrix jacchus) similar to human 13-trisomy syndrome. | this paper describes the finding of a number of malformations in a live-born common marmoset. the malformations included microphthalmia, ocular hypertelorism, cleft lip and palate and polydactyly. the findings are consistent with and strongly suggest chromosome trisomy similar to that which has been seen in man. | 1985 | 3923264 |
| changes in fatty acid composition of the cardiac phospholipids of the cotton-eared marmoset (callithrix jacchus) after feeding different lipid supplements. | after feeding marmosets different lipid supplements for 6 months, the distribution of phospholipid classes and the fatty acid composition of phosphatidylcholine (pc), phosphatidylethanolamine (pe) and diphosphatidylglycerol (dpg) were determined in their cardiac membranes. supplementing the diet with linoleic-acid-rich sunflower seed oil raised the level of 18:2,n-6 in both pc and pe, but did not change the level significantly in dpg. when 18:2,n-6 was increased, the level of arachidonic acid (2 ... | 1985 | 3922279 |
| early implantation stages in the marmoset monkey (callithrix jacchus). | the morphology of the initial stages of implantation in the marmoset monkey (callithrix jacchus) was studied by obtaining embryos and associated endometrium at timed intervals after ovulation. estrus cycles were detected by measuring daily levels of plasma progesterone. following a short follicular phase, circulating levels of progesterone above 20 ng/ml were taken as representing day 1 after ovulation. on this basis, single, twin, and triplet embryos were recovered from six perfused-fixed femal ... | 1985 | 3922211 |
| uterine rupture during labour in a common marmoset (callithrix jacchus). | 1985 | 3922101 | |
| spontaneous nasopharyngeal malignancies in the common marmoset. | 1985 | 3919492 | |
| haematological characteristics of the common marmoset (callithrix jacchus jacchus). | blood cell indices and parameters of haemostasis were studied in the common marmoset. the majority of the results were similar to those found in man. differences from man were that the prothrombin time was shorter in the marmoset, higher concentrations of aggregating stimuli were required to cause platelet aggregation, and marmoset platelets did not aggregate under the influence of adrenalin. there was sexual dimorphism evident in the data for fibrinogen concentration and for platelet count, bot ... | 1985 | 3919433 |
| plasma aminotransferase measurements in the marmoset (callithrix jacchus). | plasma aminotransferase values were measured in a large number of samples from male and female marmosets. there were no differences due to age or sex for either ast or alt. haemolysis affected values for both enzymes, though the effect on alt was greater. | 2013 | 3919214 |
| distribution of parasympathetic motoneurones in the oculomotor complex innervating the ciliary ganglion in the marmoset (callithrix jacchus). | parasympathetic motoneurones in the oculomotor complex which innervate the ciliary ganglion were identified using the horseradish peroxidase (hrp) retrograde axonal tracer technique. the ciliary ganglion was located behind the eye by a lateral orbital approach and injected with hrp pellets mounted on the tips of microelectrodes. most of the labelled cells were distributed throughout the whole edinger-westphal nucleus (ew). outside the ew, only a small number of labelled cells were found, and mos ... | 1985 | 3918402 |
| colonic mucin composition in primates. selective alterations associated with spontaneous colitis in the cotton-top tamarin. | heterogeneity of colonic mucin glycoprotein was examined in rectal mucosal biopsy specimens from a variety of primate species (saguinus oedipus, n = 18; macaca mulatta, n = 2; macaca fascicularis, n = 2; aotus trivirgatus, n = 2; saimiri sciureus, n = 2; and callithrix jacchus, n = 2). after initial separation of radiolabeled mucin and nonmucin glycoproteins solubilized from mucosal biopsy specimens, at least five labeled mucin components were found in monkey rectal mucosa in contrast to the six ... | 1985 | 3917260 |
| oculomotor areas involved in the parasympathetic control of accommodation and pupil size in the marmoset (callithrix jacchus). | the motoneurons of the oculomotor complex responsible for controlling accommodation and pupil size of the marmoset were identified by injecting horseradish peroxidase (hrp) into the ciliary ganglion. the anatomical organization of accommodation and pupil constrictor motoneurons was determined using electrical stimulation techniques. hrp-labelled cells were found through the whole length of the edinger-westphal nucleus (ew) and also just ventral to this nucleus in caudal sections. a projection fr ... | 1985 | 3835987 |
| the effects of cryopreservation and transfer on embryonic development in the common marmoset monkey, callithrix jacchus. | embryos were collected at the 4-10-cell stage from the oviducts (day 4; day 1 = ovulation) or as morulae (day 7) from the uterus of marmosets and frozen in 1.5 m-dmso (days 4 and 7) or 1.0 m-glycerol (day 4 only), using a slow freezing and thawing technique. of 22 day-4 embryos frozen in dmso, 18 were recovered and 16 of these were transferred to 10 synchronized recipients; 7 recipients became pregnant compared with all 7 control recipients receiving 10 unfrozen embryos. fifteen frozen-thawed mo ... | 1987 | 3820175 |
| frequency representation in auditory cortex of the common marmoset (callithrix jacchus jacchus). | the location and characteristics of the primary auditory cortex of the common marmoset, callithrix jacchus jacchus, were determined in five anesthetized male adult animals by mapping the responses of cortical units and unit clusters to pure tone stimuli presented to the contralateral ear. the primary auditory cortex lies largely ventral to the lateral sulcus, the only major fissure on the lateral cortex of this smooth-brained primate, but in some animals it may extend significantly down the vent ... | 1986 | 3782506 |
| postnatal development of quantitative morphological parameters in the lateral geniculate nucleus of the marmoset monkey. | quantitative morphological parameters were studied in the lateral geniculate nucleus (lgn) of the marmoset monkey (callithrix jacchus) during development, using a series of 14 animals, at ages from birth to adulthood. they include the volume of the lgn and of its layers and interlaminar zones, their neuronal content expressed as numerical density and total number, and the density and number of glial cells in the nucleus as a whole. the volume of the lgn increases rapidly after birth, reaches a m ... | 1986 | 3779436 |
| effects on the behavior of infant common marmosets (callithrix jacchus) of separation from caregivers and of drug-induced reduction in caregiver responsiveness. | the effects of separating 4-week-old twin marmosets for 8 days from their families are compared with the effects of leaving 4-week-old infants with their families, but reducing the responsiveness of their caregivers for 8 days by administration of the tranquilizer fluphenazine decanoate. both treatments reduce infant mobility, abolish play, and increase the time that infants spend with each other. during the period after the termination of the treatment, both treatment groups continue to play an ... | 1986 | 3758486 |
| mercapturic acid formation in the marmoset (callithrix jacchus). | benzylmercapturic acid is a major metabolite of [methylene-14c]benzyl chloride in the marmoset, as in the rat. the excretion of the minor metabolites benzylmercapturic acid sulphoxide and benzylcysteine accounted for a greater proportion of the dose than in the rat. excretion of hippuric acid as a metabolite of benzyl chloride was variable in the marmoset. acetylation of s-benzyl- and s-pentyl-l-cysteine to the corresponding mercapturic acids was extensive in the marmoset. trace amounts of the s ... | 1986 | 3751115 |
| genital sensory feedback and sexual behaviour in male and female marmosets (callithrix jacchus). | local anaesthesia (using lidocaine) of the penis, or of the vagina and cervix caused marked changes in the sexual behaviour of marmosets. penile desensitization did not affect sexual arousal or erectile capacity. however, intromission latencies increased and 7 out of 10 males failed to intromit during some post-lidocaine tests. females failed to show several behavioural patterns which normally occur during intromission (shrugging body movements, head turning and opening the mouth) or exhibited t ... | 1986 | 3749303 |
| anteromedial hypothalamic lesions block proceptivity but not receptivity in the female common marmoset (callithrix jacchus). | the sexual behavior of 8, estradiol-treated, ovariectomized common marmosets was recorded prior to and after bilateral radiofrequency lesions of the hypothalamus. lesions of the anterior hypothalamus, which extended to varying degrees into the medial hypothalamus, virtually abolished proceptive tongue-flicking and staring displays. tongue-flicking during copulation also decreased, but the females did not show any significant increase in the number of mounts which they refused or terminated with ... | 2012 | 3730822 |
| proceptive displays of the female common marmoset (callithrix jacchus): effects of ovariectomy and oestradiol 17 beta. | proceptivity in the common marmoset consisted of brief periods when females remained with body and limbs immobile (im) or crouched, and then stared, lipsmacked and tongue-flicked at males. treatment of ovariectomized females with oestradiol activated all these proceptive displays but did not influence the combinations in which they occurred during im periods. | 2013 | 3714875 |
| animal models of mycoplasma genitalium urogenital infection. | male and female animals were inoculated urogenitally with mycoplasma genitalium, recovered originally from men with nongonococcal urethritis. mice, hamsters and male rhesus monkeys (macaca mulatta) were resistant. male cynomolgus monkeys (macaca fascicularis) were not as sensitive as male chimpanzees (pan troglodytes): 9 of 11 developed an obvious genital tract infection, some shedding organisms for more than 18 weeks. m. genitalium was recovered from the blood of two of them when large numbers ... | 1987 | 3667225 |
| continuous light environment has no effect on the circadian testosterone rhythm, spermatogenesis or fertility of the marmoset (callithrix jacchus). | maintenance of adult male marmosets in continuous light for 60 days had no effect on the circadian rhythmicity of plasma testosterone levels, spermatogenesis or fertility. the results indicate that photoperiodicity is not the environmental determinant that regulates reproduction in male marmosets. | 1987 | 3654016 |
| radionuclide angiographic study of the influence of dietary lipid supplements on cardiac function in the marmoset (callithrix jacchus). | radionuclide angiography was used to examine the influence of dietary fat on cardiac function in the common marmoset monkey (callithrix jacchus jacchus) under barbiturate anaesthesia. animals were fed for 6-8 months with a low fat (4.5%) reference diet or the same diet supplemented (12%) with sunflower seed oil or sheep fat. although there was a tendency towards increased heart rate, left ventricular ejection fraction, peak ejection rate, and peak filling rate in both fat supplemented groups, si ... | 1987 | 3652103 |
| fetal brain development in response to iodine deficiency in a primate model (callithrix jacchus jacchus). | the common cotton-eared marmoset (callithrix jacchus jacchus) has been used for the first time as a primate model to study the effects of dietary iodine deficiency on fetal brain development. paired male and female marmosets were fed a low-iodine diet of maize, peas, meat meal, torula yeast, maize oil and added vitamins, minerals and amino acids for 6 months before mating. offspring from first and second pregnancies were compared with offspring from control marmosets fed the same diet but supple ... | 1987 | 3612176 |
| failure of the prostaglandin f2 alpha analogue, cloprostenol, to induce functional luteolysis in the olive baboon (papio cynocephalus anubis). | the prostaglandin f2 alpha analogue, cloprostenol, which is an effective luteolytic agent in the common marmoset, was administered intramuscularly to olive baboons to determine if it possessed luteolytic properties in this species. the results showed that functional luteolysis was not induced when cloprostenol was administered during the mid- to late luteal phase or during early pregnancy. | 1987 | 3585971 |
| elevated urinary excretion of beta-aminoisobutyric acid and exposure to inorganic lead. | beta-aminoisobutyric acid (beta-aib), a normal degradation product of thymine, a constituent of dna and, to a lesser extent, of transfer rna, is excreted in low levels in human urine. we found that a group of iron workers occupationally exposed to inorganic lead excreted high levels of urinary beta-aib. elevated urinary excretion of beta-aib was also observed in marmosets, callithrix jacchus, that received lead acetate in drinking water. our results suggest that increased urinary excretion of be ... | 1987 | 3579372 |
| effects of adrenalectomy upon proceptivity, receptivity and sexual attractiveness in ovariectomized marmosets (callithrix jacchus). | the sexual behaviour of seven pairs of marmosets was observed during blocks of 30 minute tests before and after the ovariectomized partners were bilaterally adrenalectomized. adrenalectomized females were maintained by intramuscular injections of deoxycorticosterone pivalate (dc) and hydrocortisone hemisuccinate (hc). twice daily injections of hc were required to maintain the high levels of plasma cortisol typical of marmosets and some other new world primates. adrenalectomy had no significant e ... | 1987 | 3575496 |
| the dopamine neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp) produces histological lesions in the hypothalamus of the common marmoset. | the administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp) to marmosets resulted in parkinsonism and degeneration of the substantia nigra pars compacta. examination of the hypothalamus showed neuronophagic-like rosettes of glial cells and diffuse increase in glial numbers in areas of the dopaminergic a11-a14 groups. these findings suggest that mptp may be toxic to dopamine neurons of the hypothalamus as well as to the substantia nigra. | 2012 | 3486388 |
| controlled ovulation in the marmoset monkey (callithrix jacchus) with human chorionic gonadotropin following prostaglandin-induced luteal regression. | controlled induction of ovulation in the marmoset monkey was attempted with a single injection of human chorionic gonadotropin (hcg; 50 iu) given on day 7 after prostaglandin-induced luteal regression. animals given hcg (n = 12) ovulated within a 2-day period (days 9 and 10 after prostaglandin) compared with a 4-day period (days 9 to 12) in the control group (n = 12). the mean interval to ovulation was similar in both groups. there was no difference in the timing of the preovulatory estradiol (e ... | 1987 | 3475217 |
| the influence of linoleate and vitamin e from sunflower seed oil on platelet function and prostaglandin production in the common marmoset monkey. | vitamin e and linoleate, both of which are found in high concentrations in sunflower seed oil, were examined independently for their influence on general and blood-vascular parameters in vitamin e-deficient common marmosets. a vitamin e-deficient diet (-e, 4 micrograms/g) was supplemented with either 40 micrograms/g vitamin e (+e), vitamin e stripped sunflower oil (+10% sso-e), or sso (+10% sso w/w) in a 2 x 2 factorial designed experiment, and the diets fed for 9 months to 4 even groups of comm ... | 1987 | 3437342 |
| embryotoxic effects of thalidomide derivatives in the non-human primate callithrix jacchus. ii. elucidation of the susceptible period and of the variability of embryonic stages. | data are presented on the normal intra- and inter-litter variability of the embryonic stages in the common marmoset (callithrix jacchus) on day 56 of pregnancy. the embryology of the marmoset is described with respect to the susceptible period for the teratogenic action of thalidomide. | 1988 | 3355363 |
| embryotoxic effects of thalidomide-derivatives in the non-human primate callithrix jacchus. i. effects of 3-(1,3-dihydro-1-oxo-2h-isoindol-2-yl)-2,6-dioxopiperidine (em12) on skeletal development. | the response of pregnant marmosets (callithrix jacchus) to the thalidomide derivative em 12 was evaluated. em 12 was selected for these studies because it is more active than thalidomide and is much more stable for hydrolysis. skeletal gross structural abnormalities were observed when em 12 was given to marmosets for 3-7 days during the period between days 49 and 60 post ovulation. using the treatment schedule finally adapted in our laboratory, i.e. treatment during days 51-57 post ovulation, do ... | 1988 | 3355362 |
| effect of iodine deficiency on craniofacial growth in young common marmosets (callithrix jacchus). | the effects of iodine deficiency on general and craniofacial growth were determined in young common marmosets. examinations, including direct measurement, cephalometric radiology, and dental examination, were performed at three-month intervals from birth to 1 year on a cross-sectional sample of three groups of marmosets. the groups were those on a normal diet, n = 50; an iodine-deficient diet during gestation and for 1 year postnatally, n = 26; and an iodine-deficient diet only during gestation ... | 1988 | 3209685 |
| embryotoxic effects of thalidomide derivatives on the non-human primate callithrix jacchus; 3. teratogenic potency of the em 12 enantiomers. | the teratogenic potencies of the enantiomers of 2-(2,6-dioxopiperidine-3-yl)-phthalimidine ( = em 12), a teratogenic thalidomide analogue, were investigated in callithrix jacchus, a primate very sensitive to the teratogenic action of this thalidomide analogue. the results indicate that the s-(-)-form of em 12 is clearly more teratogenic than the r-(+)-form. the interpretation of the studies designed to evaluate stereo-selective differences in the teratogenicity of the enantiomers becomes difficu ... | 1988 | 3196154 |
| the dopamine d2 agonist ly 141865, but not the d1 agonist skf 38393, reverses parkinsonism induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp) in the common marmoset. | marmosets treated with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp) (1-4 mg/kg i.p. daily for up to 8 days) develop profound parkinsonian akinesia. administration of the d1 agonist skf 38393 (1-20 mg/kg i.p.) 4-6 weeks later had no effect on the motor activity of animals pretreated with mptp. in contrast, the administration of the d2 agonist ly 141865 (0.1 or 0.5 mg/kg i.p.) caused a marked increase in motor activity lasting for up to 2 h. we conclude that stimulation of d2 dopamine recep ... | 1985 | 3162113 |
| evaluation of seven test kits for the detection of pregnancies in the common marmoset, callithrix jacchus. | 1988 | 3151193 | |
| dna 'fingerprinting' of captive family groups of common marmosets (callithrix jacchus). | 1988 | 3150839 | |
| the parasite trichospirura leptostoma associated with wasting disease in a colony of common marmosets, callithrix jacchus. | 1988 | 3150838 | |
| coprophagy in marmosets due to insufficient protein (amino acid) intake. | in the course of experiments to study the minimal protein requirement of common marmosets by nitrogen balance methods, coprophagy was observed. it occurred in most animals fed diets either with a protein content below 6% or lacking histidine/arginine. the protein level of 6% had previously been evaluated as being the minimal protein requirement for maintenance of marmosets. | 1988 | 3148060 |
| kin preference in marmosets and tamarins: saguinus oedipus and callithrix jacchus (callitrichidae, primates). | field studies on callitrichid primates have suggested that some species may exhibit a communal breeding system in which two or more males mate with a single female and cooperatively participate in infant rearing. however, high levels of aggression have been observed between males under both laboratory and field conditions. in avian models for communal breeding, cooperating males are often closely related. in a laboratory test of a hypothesis of the amelioration of aggression based on kinship, fo ... | 2011 | 3147598 |
| effects of dorsal penile nerve transection upon the sexual behaviour of the male marmoset (callithrix jacchus). | the sexual behaviour of 7 adult male marmosets and their ovariectomized partners was observed during pair-tests before and after bilateral dorsal penile nerve transection (n = 4) or a sham operation (n = 3). after transection of the dorsal penile nerves, males mounted more frequently and the initial mount of each test was more prolonged. males continued to orientate correctly during mounts and to make rapid pelvic thrusts, with the erect penis close to the vaginal orifice. however, the deep pelv ... | 1988 | 3145513 |
| comparative chromosome morphology in three callitrichid genera: cebuella, callithrix, and leontopithecus. | a g-band karyotypic analysis was carried out in individual species groups of three callitrichid primate genera: cebuella, callithrix, and leontopithecus. within callithrix, the karyotypes of the morphologically distinct and geographically isolated morphotypes c. jacchus jacchus and c. jacchus penicillata were identical. within the lion tamarin genus, leontopithecus, the karyotypes of the three morphotypes (l. rosalia rosalia, l. rosalia chrysomelas and l. rosalia chrysopygus) were also indisting ... | 2010 | 3145301 |
| effects of hypothalamic lesions upon the sexual and social behaviour of the male common marmoset (callithrix jacchus). | the sexual and associated behaviour of 10 adult male marmosets was recorded during pair tests with ovariectomized females, before and after bilateral thermal lesions of the hypothalamus. four sham-lesioned males served as controls. lesions varied in volume from 1.49 to 3.28 mm3 and extended from the ventromedial hypothalamus to the diagonal band of broca. precopulatory behaviours (anticipatory erections, tongue flicking and anogenital investigations of the female) as well as frequencies of mount ... | 1988 | 3143470 |
| the enantiomers of the teratogenic thalidomide analogue em 12: 1. chiral inversion and plasma pharmacokinetics in the marmoset monkey. | the plasma pharmacokinetics of the enantiomers of 2-(2,6-dioxopiperidine-3-yl)-phthalimidine (em 12) and the racemic mixture of this substance were investigated in callithrix jacchus, a thalidomide-sensitive primate. single doses of 5 mg/kg body wt were administered orally or intraperitoneally. maximum plasma concentrations were reached 1 h after administration of the enantiomers, and 3 h after application of the racemate. the mean plasma elimination half-life was in the range of 5 h for the ena ... | 1988 | 3143339 |
| polymorphism of visual pigments in a callitrichid monkey. | microspectrophotometric measurements of visual pigments have been obtained for a large sample of new world monkeys of the species callithrix jacchus jacchus. these animals exhibit a polymorphism of visual pigments. the rods (lmax 499 nm) and the short-wave receptors (lmax 423 nm) appear to be common to all animals but individuals differ in the number and spectral position of pigments in the green-yellow spectral region. the latter pigments cluster near 545, 559 and 567 nm. male monkeys draw one ... | 1988 | 3143179 |
| administration of mptp to the common marmoset does not alter cortical cholinergic function. | the administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp) to common marmosets induced persistent motor deficits and decreased concentrations of dopamine, homovanillic acid, and 3,4-dihydroxy-phenylacetic acid (dopac) and [3h]dopamine uptake in the caudate-putamen. there was an 80% reduction in tyrosine hydroxylase immunoreactive cells in substantia nigra. at 10 days following the start of mptp administration, the activity of choline acetyltransferase in the thalamus and frontal c ... | 1986 | 3143064 |
| embryonic signals during the peri-implantation period in primates. | during the peri-implantation period of pregnancy in primates, chorionic gonadotrophin (cg) is the first clear signal of the embryo's presence and viability. in the marmoset (callithrix jacchus) implantation begins on day 11-12 after ovulation and cg is secreted by the embryo from this time. the inner cell mass is necessary for the normal secretion of cg by the trophoblast. implantation can be disrupted both in vivo and in vitro by antisera to the hcg-beta subunit. the secretion of a platelet act ... | 1988 | 3142993 |
| distribution of motoneurones innervating extraocular muscles in the brain of the marmoset (callithrix jacchus). | extraocular muscle motoneurones were localised in the oculomotor nucleus (on), trochlear nucleus (tn) and abducens nucleus (an) in the marmoset brain using the horseradish peroxidase (hrp) retrograde labelling technique. hrp pellets injected into individual extraocular muscles revealed one or more groups of labelled neurones occupying discrete loci within these nuclei. relatively little overlap of motoneurone pools was observed, except in the case of the inferior oblique and superior rectus musc ... | 1987 | 3142199 |
| effects of acute stress on the patterns of lh secretion in the common marmoset (callithrix jacchus). | stressful stimuli associated with aggressive encounters and low social rank may affect female fertility in a variety of mammalian species. in these experiments we examined the effects of aggressive encounters and physical restraint in a primate chair on the patterns of lh secretion in ovariectomized, oestrogen-primed female marmosets. receipt of aggression from a female conspecific, followed by physical restraint for collection of blood samples (at 10-min intervals for 4 h), resulted in marked d ... | 1988 | 3139816 |
| births following the transfer of cultured embryos obtained by in vitro and in vivo fertilization in the marmoset monkey (callithrix jacchus). | the aim of this study was to determine whether marmoset monkeys are a suitable primate model for in vitro fertilization (ivf), embryo culture, and transplantation studies. a prostaglandin analogue given in early pregnancy and human chorionic gonadotropin given near the end of the ensuing follicular phase were used for controlling the reproductive cycle, timing oocyte collection, and synchronizing the cycles of oocyte donors and embryo recipients. five embryos obtained by ivf were transferred at ... | 1988 | 3137105 |
| a restraint system for the common marmoset (callithrix jacchus). | a method for restraining the marmoset in a primate chair is described. the device is inexpensive to construct, is reliable, and the majority of animals can be habituated to its use. the chair has been used in neurobiological studies employing electrophysiological recordings, with or without concurrent collection of serial blood samples. | 1988 | 3134573 |
| social status controls lh secretion and ovulation in female marmoset monkeys (callithrix jacchus). | the suppression of ovulation in subordinate female marmosets was associated with suppressed pituitary lh secretion and reduced pituitary lh response to gonadotrophin-releasing hormone (gnrh). in subordinate females, basal plasma lh concentrations were commonly below 2 iu/l (n = 5) (maximum 10.7 iu/l). plasma oestrogen concentrations were similarly low (maximum 0.62 nmol/l) and plasma progesterone concentrations of below 30 nmol/l confirmed the anovulatory condition. this infertility condition wa ... | 1988 | 3134506 |
| cellular aspects of pre-ovulatory folliculogenesis in primate ovaries. | according to current concepts of pre-ovulatory folliculogenesis in primate ovaries, each growing follicle has a 'threshold' requirement for stimulation by fsh which must be met if it is to enter the oestrogen-secretory phase of pre-ovulatory development. until recently, our understanding of the intra-follicular mechanisms underlying fsh action on granulosa cells was based largely on information from non-primate laboratory animals, mainly polyovulators such as rats. the present paper describes st ... | 1988 | 3134394 |
| effect of various biological factors on spontaneous marmoset and tamarin colitis. a retrospective histopathologic study. | histological sections of colons from 69 tamarins (46 saguinus oedipus and 23 saguinus fuscicollis illigeri) and 27 marmosets (callithrix jacchus) that died between 1979 and 1984 were examined for colitis. evaluated biological factors were species, age at death, source of animals, manner of death, presence of colon cancer, and time after importation. most normal colons were found in young animals (dead at less than 1 years of age). nearly all (approximately 96%) animals had colitis; 70-80% of mos ... | 1988 | 3134175 |
| characterization of colonic cellular glycoconjugates in colitis and cancer-prone tamarins versus colitis and cancer-resistant primates. | differences in colonic secretory glycoconjugates (ie, mucin) between normal and ulcerative colitis-prone patients have been noted. similar differences may occur in a corresponding primate model, the cotton-top tamarin (ctt), saguinus oedipus, a new world monkey which suffers from spontaneous chronic colitis and colon cancer. lectin reagents were used to characterize and compare colonic cell surface, cytoplasmic, and secretory glycoconjugates of 9 clinically healthy cotton-top tamarins, 7 colitis ... | 1988 | 3132857 |
| effect of antiprogestin zk 98.734 on the ovarian cycle, early pregnancy, and on its binding to progesterone receptors in the myometrium of marmoset callithrix jacchus. | the antiprogestin zk 98.734 (11 beta-(4-dimethylaminophenyl-17 beta-hydroxy-17 alpha-(3-hydroxy-prop-1(z)-enyl-4,9(10)-estradien-3-one) was administered i.m. (5 mg/day) for three consecutive days to two groups of common marmosets. in one group (nonpregnant, n = 6), it was injected during the luteal phase, and to the second group (pregnant, n = 7), it was injected during early pregnancy, on days 24-26 of the mid-cycle estradiol peak. administration of zk 98.734 during the luteal phase caused a sh ... | 1988 | 3132210 |
| plasmodium vivax malaria in the common marmoset, callithrix jacchus: adaptation and host response to infection. | infection with plasmodium vivax was established in splenectomized callithrix jacchus marmosets by inoculation of parasitized blood from aotus trivirgatus carrying the vietnam palo-alto line of p. vivax. subsequent blood passage through intact marmosets resulted in higher peak parasitaemias (about 1% of red cells infected) and the loss of stainable schüffner's dots in infected cells. primary infections with the adapted line were patent for 74 days or more, and induced both a substantial antibody ... | 1988 | 3131721 |
| endogenous n-excretion and minimal protein requirement for maintenance of the common marmoset (callithrix jacchus). | the protein requirement for maintenance of the marmoset callithrix jacchus was investigated by factorial calculation via the n balance technique. six adult male marmosets were fed a protein-free pelleted diet for 22 days. when a low protein diet (6%) was fed in the preperiod, only 7 days were necessary and when fed a higher protein diet (18%) 10 days were necessary to reach a minimum of n excretion during protein depletion. body weight losses averaged 11% and food intake was 21% lower in the pro ... | 1988 | 3131585 |
| factors influencing follicle-stimulating hormone-responsive steroidogenesis in marmoset granulosa cells: effects of androgens and the stage of follicular maturity. | preovulatory changes in the steroidogenic function of primate granulosa cells were studied using the cyclic marmoset (callithrix jacchus) as a model. antral follicles (greater than or equal to 0.5 mm diameter) were dissected from mid-late follicular phase ovaries (7 days after prostaglandin-induced luteolysis) and classified by diameter as small (0.5-1.0 mm), medium (1.1-1.9 mm) or large (greater than or equal to 2.0 mm). granulosa cells from follicles in each size category were isolated and poo ... | 1988 | 3131124 |
| identification of the main gestagen metabolite in marmoset (callithrix jacchus) urine by nmr and ms spectroscopy. | hydroxypregnanolone is the most abundant progesterone metabolite in the urine of marmoset monkeys (callithrix jacchus). the substance is excreted as conjugate. the concentration of this steroid may be monitored by high performance, thin layer chromatography and postchromatographic derivatization. hydroxypregnanolone was purified and subsequently identified by nmr spectroscopy and gas chromatography/mass spectroscopy. the exact chemical structure is 5 alpha-pregnane-3 alpha, 7 alpha-diol-20-one. | 1988 | 3130485 |
| induction of luteal regression in the marmoset monkey (callithrix jacchus) by a gonadotrophin-releasing hormone antagonist and the effects on subsequent follicular development. | doses of 100 or 200 micrograms of a novel gnrh antagonist ([n-acetyl-d beta na11-d-pcl-phe2-d-phe3-d-arg6-phe7-arg8-d-ala10]nh2 gnrh) (4 animals/dose) were administered on days 10/11 of the luteal phase and induced a marked suppression of circulating bioactive lh and progesterone concentrations within 1 day of treatment (p less than 0.01). thereafter, progesterone concentrations remained low or undetectable until after the next ovulation. similar results were obtained when 200 micrograms antagon ... | 1988 | 3129559 |
| postnatal development of dendrites of relay neurons in the lateral geniculate nucleus of the marmoset (callithrix jacchus): a quantitative golgi study. | dendrites of multipolar relay neurons in the lateral geniculate nucleus of the marmoset (callithrix jacchus), at various ages from birth to adulthood, were studied in rapid golgi preparations. the dendrites were analyzed by means of three-dimensional computer reconstructions and decomposed into intermediate and terminal segments, both of which were further classified according to their centrifugal order. measurements were made of the number of segments per dendrite, the total length of dendrites ... | 1988 | 3129457 |
| connections of the primary auditory cortex in the common marmoset, callithrix jacchus jacchus. | the afferent and efferent connections of the primary auditory cortex (ai) of common marmosets were traced following small injections of wheat germ agglutinin conjugated with horseradish peroxidase (wga-hrp) made at best frequency (bf)-defined sites in the ai. after the injections the animals remained anesthetized for 15-23 hours; they were then perfused transcardially with fixative and the brains were processed for wga-hrp reaction product. examination of the disposition of labelled material rev ... | 1988 | 3128585 |
| post-partum changes in hormones and sexual behaviour in captive groups of marmosets (callithrix jacchus). | video-tape recordings were made of behavioural interactions in eight family groups of marmosets for 24-30 days after parturition. blood samples were collected from females for measurement of plasma luteinizing hormone (lh) and progesterone. a pre-ovulatory lh surge occurred in six females between days 10-18 (mean +/- sem, 13.8 +/- 1.3 days). in these groups, sexual interactions increased in frequency during the post-partum period and males began to initiate mounts on days 1, 2, 2, 6, 8 and 10 re ... | 1987 | 3126512 |
| chronic toxicity of 3,4,3',4'-tetrachlorobiphenyl in the marmoset monkey (callithrix jacchus). | cotton top marmoset monkeys (callithrix jacchus) were orally dosed with 3, 1, 0.1 or 0 mg 3,4,3',4'-tetrachlorobiphenyl (tcb)/kg body weight twice per week for 18-23 weeks. severe toxicity occurred in the highest dose group. clinical signs of toxicity were a rapid decrease in body weight, alopecia, abnormal nail growth, nodular enlargement of the nipple area and scaly skin. haematological analysis of peripheral blood revealed mild leukocytosis and anemia. biochemical alterations observed were el ... | 1988 | 3124295 |
| chronic colitis in common marmosets (callithrix jacchus) and cotton-top tamarins (saquinus oedipus). | 2011 | 3122405 | |
| characteristics of trophoblastic tissue derived from in vitro culture of preimplantation embryos of the common marmoset monkey. | the features of trophoblastic tissue derived from the in vitro culture of marmoset monkey embryos have been described. long-term trophoblast cultures (in excess of three years in one case) were established from the primary trophoblast monolayer of four of 38 embryos; division of one of these embryos produced two long-term cultures. the trophoblast cells retained their ability to synthesize and secrete chorionic gonadotrophin (cg) during maintenance in vitro and were capable of prolonging the lut ... | 1987 | 3120174 |
| difference in serum ascorbate in two species of callithricidae. | in one species each of the subfamilies marmosets and tamarins of the new world monkey family callithricidae, serum levels of ascorbic acid were compared. although the feeding regimen had been the same for both species for several years, the average concentration of serum ascorbate in the tamarins saguinus fuscicollis (n = 21; 0.54 +/- 0.29 mg/100 ml) was only one-fifth that of the marmosets callithrix jacchus (n = 19; 2.56 +/- 1.07 mg). | 1987 | 3119508 |
| partial purification and characterization of chorionic gonadotrophin in plasma and in culture medium of trophoblast cells from the marmoset monkey (callithrix jacchus). | a biologically active gonadotrophin has been purified from the media of long-term cultures of trophoblast cells of the common marmoset monkey by a combination of precipitation and chromatography. marmoset chorionic gonadotrophin (cg) is a glycoprotein which binds concanavalin a and wheat germ agglutinin. the protein purified from culture media exists as several isoelectric species with pi in the range ph 3.5-4.5. on gel filtration it eluted with an apparent molecular weight of 68-72,000 but on p ... | 1987 | 3116232 |
| the measurement of ethylenethiourea and ethyleneurea in the rat and common marmoset callithrix jacchus after zineb (zinc ethylenebisdithiocarbamate) dosing. | the metabolism of the fungicide zineb, (zinc ethylenebisdithiocarbamate), has been studied in the rat and the marmoset. 2. it was found in both species that a relatively large proportion (21-22%) of the original zineb administered was detectable in the excreta as ethylenethiourea (etu) a known mutagen, teratogen and carcinogen. 3. a further proportion (2-5%) was determined to be ethyleneurea which is a metabolite of etu. 4. results of comparative experiments in marmosets revealed that etu was ph ... | 1987 | 3114968 |
| rats and marmosets respond differently to serotonin agonists and antagonists. | the actions of the serotonin precursor 5-hydroxytryptophan (5-htp), the agonist 5-methoxy-n,n-dimetyltryptamine (meodmt) and quipazine (qpz) and the antagonists cyproheptadine, methysergide and metergoline, were studied in the rat and in the common marmoset (callithrix jacchus). the precursor and agonists elicited head shakes, forepaw padding, splayed hindlimbs, tremor and straub tail in the rat. however, head shakes were not observed after meodmt and straub tail was not observed after qpz. carb ... | 1987 | 3114802 |
| long-term data on the reproduction and maintenance of a colony of common marmosets (callithrix jacchus jacchus) 1972-1983. | we have used our laboratory records to compare data on the reproduction and maintenance of common marmosets in different colonies and to provide additional information on the species in captivity. data are presented for a period of 12 years. this was long enough to allow information on longevity, mortality, aggression and incest. in addition 543 infants were born from a total of 202 births. no seasonality was found and the highest proportion of births overall was that of triplets. a significantl ... | 1987 | 3114559 |
| ascorbic acid requirement and assessment of ascorbate status in the common marmoset (callithrix jacchus). | marmosets can tolerate an ascorbic acid (aa) deficiency for several weeks without clinical symptoms. after being fed an aa-free diet for 3 months, nonspecific deficiency symptoms became obvious. different dietary levels of aa resulted in corresponding serum ascorbate levels. the kidney threshold of aa in marmosets is comparable to that in humans. when the minimal aa requirement is defined as the amount that is necessary to maintain a serum aa level above the kidney threshold, then about 20 mg aa ... | 1987 | 3113325 |
| [spontaneous activity and eating behavior of the white-tufted marmoset (callithrix jacchus)]. | 1987 | 3113089 | |
| determination of ovulation and pregnancy in the marmoset (callithrix jacchus) by monitoring of urinary hydroxypregnanolone excretion. | in callithrix jacchus the urinary excretion of hydroxypregnanolone (5 alpha-pregnane-3 alpha, 7 alpha-diol-20-one) shows a luteal rise during the ovulatory cycle. this progesterone metabolite can therefore be used as an indication of ovulation, implantation, and subsequently for the persistence of the pregnancy. the excretion can be monitored by high performance thin-layer chromatography (hptlc) and postchromatographic derivatization after enzymatic hydrolysis of the conjugate. profiles of urina ... | 1987 | 3112406 |
| plasma testosterone concentrations during postnatal development in the male common marmoset. | repeated measurements of plasma testosterone (t) were made in 56 male marmosets from the day of birth until 300 days of age and in 44 adults (greater than 3 years). the resulting profile of plasma t during postnatal development shows higher levels during infancy (1-90 days) followed by a nadir between 100 and 170 days and then a progressive rise in t during puberty. although t levels of up to 21 ng/ml were measured in infant males, mean levels (+/- sem) were 5.4 +/- 0.6 ng/ml (days 1-10), declin ... | 1986 | 3111958 |
| the basement membrane of the persisting maternal blood vessels in the placenta of callithrix jacchus. | formation and morphology of the thickened basement membrane-like layer around the persisting maternal vessels of the callithrix jacchus placenta were investigated from day 45 until term (day 142) using light, electron and immunofluorescence microscopy. thickening occurs with the establishment of contacts between the vessels and the syncytiotrophoblast (day 48). final thickness is reached at about day 100. the course of the vessels shows wide gaps where the maternal blood flows freely into the in ... | 1987 | 3111301 |
| suboccipital puncture for cerebrospinal fluid in the common marmoset (callithrix jacchus). | cerebrospinal fluid (csf) can be obtained routinely from the common marmoset (callithrix jacchus) by suboccipital puncture. one field of research in which this method is applied is the detection of changes in the biogenic amine metabolism in csf. the puncture technique is simple and rapid and does not injure the experimental animal. | 1987 | 3110501 |
| effects of arecoline and pilocarpine on learning ability in marmosets pretreated with hemicholinium-3. | common marmosets (callithrix jacchus) were trained to perform serial reversal position discrimination tasks in a wisconsin general test apparatus. intraventricular injection of hemicholinium-3 4 h before testing resulted in a profound impairment of position discrimination learning which could be overcome by the intramuscular administration of low doses of the muscarinic agonists, arecoline or pilocarpine. | 1987 | 3108931 |
| active immunization against renin in normotensive marmoset. | primate renins (human and monkey) are very similar. we used pure human renin to immunize marmosets (callithrix jacchus) and thereby produce a chronic blockade of the renin-angiotensinogen reaction. after a control period of 2 months, five male marmosets, on their usual sodium-poor diet, were immunized against pure human renin by three subcutaneous injections of 30 micrograms each, with complete and then incomplete freund's adjuvant. three marmosets were injected with adjuvant only and served as ... | 1987 | 3108891 |
| influence of dietary fats on blood coagulation and prostaglandin production in the common marmoset. | common marmosets were fed a standard marmoset diet (ref) or diets supplemented with 12% (wt/wt) sunflower seed oil (sso) or sheep fat (sf) for a period of 90 weeks. the values for coagulation indices, clotting time, and russel viper venom time were consistent with decreased thrombotic tendency of platelets from animals on the sso diet relative to the low fat, ref diet animals, while an increased tendency to thrombosis was observed with sf-fed marmosets. the sso- and sf-supplemented marmosets sho ... | 1987 | 3107535 |
| 4-phenylpyridine and three other analogues of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine lack dopaminergic nigrostriatal neurotoxicity in mice and marmosets. | c57 black mice were injected repeatedly with maximal tolerated doses of 2 chemical analogues of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp); 4-phenylpyridine and 4-phenyl-1,2,3,6-tetrahydropyridine. although both compounds were clearly acutely toxic to mice, neither caused any reduction in striatal dopamine content after chronic exposure. two mptp analogues which may be formed endogenously during the metabolism of brain monoamines, 2-methyl-1,2,3,4-tetrahydroisoquinoline and 2-methyl-1,2 ... | 1987 | 3106859 |
| a new heterotopic callosal projection of primary visual cortex in the monkey, callithrix jacchus. | a callosal projection of area 17 upon the dorsomedial visual area in the marmoset monkey was demonstrated by means of retrograde transport of neuronal tracers. the projection was restricted to those regions representing the vertical meridian in the two areas. this finding, and the data of other authors, indicate that the monkey area 17 projects transcallosally onto homotopic and several heterotopic targets. | 1987 | 3103864 |
| the ultrastructure of early implantation in the marmoset monkey (callithrix jacchus). | the ultrastructural morphology of the initial stages of implantation in the marmoset monkey (callithrix jacchus) was studied in pregnant monkeys at known time intervals after ovulation. the earliest samples, obtained 13 days after ovulation, displayed both cytotrophoblast and syncytiotrophoblast. the cytotrophoblast was restricted to the blastocoel, whilst syncytiotrophoblast intruded to the endometrial basal lamina. at later stages, days 16 and 19 after ovulation, both cytotrophoblast and syncy ... | 1987 | 3103485 |
| effects of variable linoleate intake on aortic pgi2-like activity and fatty acid composition: difference between rat and marmoset (callithrix jacchus). | two animal species, the laboratory rat and a non-human primate (the common marmoset) were compared with respect to the influence of dietary lipid supplementation on both fatty acid composition and prostanoid synthetic capacity of aorta. standard chow (ref. diet) was supplemented (12% w/w) with either sheep fat (sf) or sunflower seed oil (sso). differences were apparent in the aortic phospholipid fatty acids from both animal models, as a result of the diet, although the type and the extent of cha ... | 1986 | 3103139 |
| short-term toxicity study of 4-dimethylaminoazobenzene in marmosets. | the marmoset, a small non-human primate, has rarely been used in toxicological studies. a short-term toxicity study was performed on common marmosets (bw = 330 +/- 32 g). fifteen male marmosets received oral administration of dab at a dose level of 56 mg/kg/day and 4 control animals received corn oil alone for a period of 15 days. hematological, biochemical, histopathological and bone marrow examinations were carried out on the 5th, 10th and 15th day of treatment. body weight decreased continuou ... | 1986 | 3102751 |
| [comparative scanning and transmission electron microscopy studies of the ependyma of the central canal in the spinal cord of primates. i. electron optical image of the ependyma in the central canal of the spinal cord of the callithrix monkey (callithrix jacchus, linné 1758)]. | the ependyma lining the central canal of the spinal cord of adult males and females monkey, callithrix jacchus, was examined by scanning and transmission electron microscopy. the cross section of the lumen of the central canal are round, oval, or triangular. light and dark ependymal cells, depending on the density of the cytoplasm, were found. the light ependymal cells are fewer than the dark cells. the ependyma cytoplasm contained numerous mitochondria, filamentous structures, one or more well- ... | 1986 | 3098621 |
| a backpack system for long-term osmotic minipump infusions into unrestrained marmoset monkeys. | a backpack system is described whereby osmotic minipumps are used to infuse gonadotrophin-releasing hormone (gnrh) subcutaneously in a pulsatile manner into infertile socially subordinate female marmoset monkeys (callithrix jacchus jacchus). this procedure enables long-term infusion of gnrh without the necessity of repeated subcutaneous implantation of pumps and gnrh reservoirs. the backpack and cannulae system is inexpensive and can be constructed from commonly available materials. the gnrh tre ... | 1986 | 3095582 |
| quantitative changes in morphological parameters in the developing visual cortex of the marmoset monkey. | several quantitative morphological parameters were measured during postnatal development in area 17 of the marmoset monkey (callithrix jacchus). in a series of 14 animals, at ages from birth to adulthood, we studied changes in the thickness, surface area and volume of area 17, as well as the neuronal and glial numerical densities, and total numbers. we found evidence for a rapid increase in thickness, area and volume, culminating between 6 weeks and 6 months postnatally, and then decreasing. the ... | 1986 | 3094833 |
| afferent connections of the substantia innominata/basal nucleus of meynert in carnivores and primates. | afferent connections to the substantia innominata/nucleus basalis complex of monkeys and cats were traced by using the method of retrograde transport of horseradish peroxidase (hrp). altogether ten injections of hrp were performed in four monkeys (saimiri sciureus, callithrix jacchus, galago senegalensis) and in four cats, with either vertical or oblique needle approaches. the entire brains excluding the olfactory bulbs and the cerebellum were then screened for labeled neurons. in both monkey an ... | 1986 | 3093564 |
| sulphoxidation of s-carboxymethyl-l-cysteine in the rhesus monkey (macaca mulatta), cynomologus monkey (macaca fascicularis), african green monkey (cercopithecus aethiops) and the marmoset (callithrix jacchus). | the metabolic pathways giving rise to the urinary metabolites of s-carboxymethyl-l-cysteine have been identified for the rhesus, cynomologus, african green and marmoset species of monkey. the formation of a sulphoxide metabolite from the sulphide precursor is a reaction important in these species. the metabolic profile displayed by the marmoset was distinct from the three old world species, with the rhesus and cynomologus being similar to man. | 1986 | 3089678 |
| bone in the marmoset: a resemblance to vitamin d-dependent rickets, type ii. | the common marmoset, a new world monkey, requires a large amount of vitamin d3 to maintain its normal growth. this monkey is reported to have an end-organ resistance to 1 alpha,25-dihydroxyvitamin d3 (1 alpha,25(oh)2d3). in this study, the bone morphology of marmosets fed a high vitamin d3 diet (intake of vitamin d3, 110 iu/day/100 g of body weight) was compared by x-ray and histological examinations with that of rhesus monkeys (old world monkey) fed a normal diet (intake of vitamin d3, 5 iu/day ... | 1986 | 3089562 |
| serum protein electrophoretic patterns of the marmoset, callithrix jacchus. | three electrophoretic procedures were used to separate protein fractions of marmoset serum. the albumin of marmoset serum migrated further than that of human serum with all three procedures and the number and size of the globulin fractions differed with species and with procedure. | 1986 | 3088068 |
| platelet measurements in the common marmoset, callithrix jacchus. | platelet counts and mean platelet volumes were determined for 39 male and 32 female adult marmoset whole blood samples and these results are compared with previously published data. there is no evidence of a difference between sexes but there is some evidence of a relationship between platelet count and mean platelet volume in the callithrix jacchus population studied. | 1986 | 3088067 |
| learning impairment following lesion of the basal nucleus of meynert in the marmoset: modification by cholinergic drugs. | five common marmosets (callithrix jacchus) received unilateral ibotenic acid lesions of the basal nucleus of meynert (nbm). seven days later, choline acetyltransferase activity was significantly reduced by 50% in the frontal and temporal neocortex, 40% in the amygdala, and approximately 30% in the motor, parietal and occipital cortex in the ipsilateral hemisphere. four marmosets receiving equivalent bilateral ibotenic acid lesions were severely impaired on new visual object discrimination learni ... | 1986 | 3087582 |
| gelatin as a vehicle for food and vitamin administration to marmosets. | for a period of three years, gelatin was used as a vehicle for administration of food, vitamin complex and drugs to laboratory maintained callithrix penicillata and callithrix jacchus marmosets and a breeding colony of c. penicillata. in both circumstances, results were satisfactory. the animals survived for long periods of time, with adult, young and juvenile primates in the breeding colony showing good physical condition. | 1986 | 3084867 |
| fate of recombinant human renin administered exogenously to anesthetized monkeys. | highly purified recombinant human renin (rh-renin), synthesized by chinese hamster ovary cells, was labeled with iodine-125 and was given intravenously to pentobarbital-anesthetized common marmosets (callithrix jacchus) to study the fate of the circulating renin. specific anti-rh-renin antiserum was used to identify the 125i-rh-renin. plasma disappearance of the exogenously administered 125i-rh-renin in marmosets (n = 6) showed two exponential components, with a half-life of 12.1 +/- 1.9 minutes ... | 1988 | 3049339 |
| successful infection of the common marmoset (callithrix jacchus) with human varicella-zoster virus. | the common marmoset, callithrix jacchus, can be infected with human varicella-zoster virus (vzv), both wild-type strain kmcc and attenuated vaccine strain oka/merck. infection was accomplished with either whole-cell-associated or cell extract vzv by combined oral-nasal-conjunctival application and was characterized by substantial and persistent anti-vzv antibody responses. the infectivity of vzv for marmosets was destroyed by treatment of inocula with heat or uv light. diluted inocula with as fe ... | 1987 | 3041014 |
| localization of neurotensin receptors in the forebrain of the common marmoset and the effects of treatment with the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. | the distribution of neurotensin binding sites was mapped in the brain of the common marmoset using [3h]neurotensin as the ligand. autoradiographic techniques show that the density of receptors is particularly high in the substantia nigra, ventral tegmental area, olfactory tubercle and cerebral cortex and that the distribution of neurotensin receptors in the cerebral cortex and striatum is heterogenous. in the cerebral cortex neurotensin receptors are concentrated in layers i, ii, iii and v, whil ... | 1987 | 3038264 |
| protection of junín virus-infected marmosets by passive administration of immune serum: association with late neurologic signs. | argentine hemorrhagic fever (junín virus) is a human viral disease for which immune therapy proves effective, though a late neurologic syndrome is occasionally associated with the treatment. we attempted to determine in the infected marmoset callithrix jacchus whether immune therapy leads to protection and/or cns damage. fifteen c jacchus were inoculated with 10(3) tissue culture infectious dose 50% (tcid50) of the xj strain of junín virus. on day 6 post infection (pi), 12 primates were treated ... | 1987 | 3025358 |