Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
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| zika virus challenges for neuropsychiatry. | before 2007, zika virus (zikv) was generally considered as an arbovirus of low clinical relevance, causing a mild self-limiting febrile illness in tropical africa and southeast asia. currently, a large, ongoing outbreak of zikv that started in brazil in 2015 is spreading across the americas. virus infection during pregnancy has been potentially linked to congenital malformations, including microcephaly. in addition to congenital malformations, a temporal association between zikv infection and an ... | 2016 | 27478378 |
| easy and inexpensive molecular detection of dengue, chikungunya and zika viruses in febrile patients. | dengue (denv), chikungunya (chikv) and zika (zikv) are arthropod-borne viruses (arboviruses) sharing a common vector, the mosquito aedes aegypti. at initial stages, patients infected with these viruses have similar clinical manifestations, however, the outcomes and clinical management of these diseases are different, for this reason early and accurate identification of the causative virus is necessary. this paper reports the development of a rapid and specific nested-pcr for detection of denv, c ... | 2016 | 27477452 |
| dengue in a changing climate. | dengue is the world's most important arboviral disease in terms of number of people affected. over the past 50 years, incidence increased 30-fold: there were approximately 390 million infections in 2010. globalization, trade, travel, demographic trends, and warming temperatures are associated with the recent spread of the primary vectors aedes aegypti and aedes albopictus and of dengue. overall, models project that new geographic areas along the fringe of current geographic ranges for aedes will ... | 2016 | 27475051 |
| one-pot fabrication of silver nanocrystals using nicandra physalodes: a novel route for mosquito vector control with moderate toxicity on non-target water bugs. | mosquitoes (diptera: culicidae) as vectors for important diseases and parasites causing millions of deaths every year. the use of synthetic pesticides against culicidae leads to resistance and environmental concerns. therefore, eco-friendly control tools are a priority. in this research, nicandra physalodes-mediated synthesis of silver nanoparticles (ag nps) was conducted, in order to control larval populations of three important mosquito vectors, anopheles stephensi, aedes aegypti and culex qui ... | 2016 | 27473981 |
| chikugunya and zika virus dissemination in the americas: different arboviruses reflecting the same spreading routes and poor vector-control policies. | this review gathers the most recent investigations about chikungunya and zika viruses in america and would help in creating new research approaches. | 2016 | 27472289 |
| advances and perspectives in the application of crispr/cas9 in insects. | insects compose more than half of all living organisms on earth, playing essential roles in global ecosystems and forming complex relationships with humans. insect research has significant biological and practical importance. however, the application of genetic manipulation technology has long been restricted to several model insects only, such as gene knockout in drosophila, which has severely restrained the development of insect biology research. recently, with the increase in the release of i ... | 0 | 27469253 |
| zika virus: a new arboviral public health problem. | zika virus (zikv) is a single-stranded rna virus in the flaviviridae family and transmitted to human through infected mosquitos (aedes aegypti and aedes albopictus). virus is closely related with other flaviviruses; dengue virus, yellow fever virus, west nile virus, and japanese encephalitis virus phylogenetically. due to the possible relationship between virus and clinical features including microcephaly, ventricule, and eye deformities, guillain-barre syndrome increases the interest on this vi ... | 2016 | 27469112 |
| preventing zika virus infection during pregnancy using a seasonal window of opportunity for conception. | it has come to light that zika virus (zikv) infection during pregnancy can result in trans-placental transmission to the fetus along with fetal death, congenital microcephaly, and/or central nervous system (cns) malformations. there are projected to be >9,200,000 births annually in countries with ongoing zikv transmission. in response to the zikv threat, the world health organization (who) is strategically targeting prevention of infection in pregnant women and funding contraception in epidemic ... | 2016 | 27467271 |
| storm drains as larval development and adult resting sites for aedes aegypti and aedes albopictus in salvador, brazil. | dengue (denv), chikungunya (chikv), zika (zikv), as well as yellow fever (yfv) viruses are transmitted to humans by aedes spp. females. in salvador, the largest urban center in north-eastern brazil, the four denv types have been circulating, and more recently, chikv and zikv have also become common. we studied the role of storm drains as aedes larval development and adult resting sites in four neighbourhoods of salvador, representing different socioeconomic, infrastructure and topographic condit ... | 2016 | 27464886 |
| zika. an emerging teratogenic virus. | [no abstract available]. | 0 | 27464857 |
| comparative performance of transcriptome assembly methods for non-model organisms. | the technological revolution in next-generation sequencing has brought unprecedented opportunities to study any organism of interest at the genomic or transcriptomic level. transcriptome assembly is a crucial first step for studying the molecular basis of phenotypes of interest using rna-sequencing (rna-seq). however, the optimal strategy for assembling vast amounts of short rna-seq reads remains unresolved, especially for organisms without a sequenced genome. this study compared four transcript ... | 2016 | 27464550 |
| bioethical considerations at times of zika virus. | 0 | 27462882 | |
| dengue deaths: associated factors and length of hospital stay. | background. dengue continues to pose a public health problem globally. objective. to review factors associated with patients who died from dengue in trinidad. methods. a retrospective case note review of hospitalized patients who died during 2001 to 2010. results. a total of 23 cases were identified: 13 males, 10 females-12 east indians, 9 africans, and 2 unknown. more than half (n = 17) were over 40 years of age with 10 being over 60 years of age; three were children. a falling platelet count w ... | 2016 | 27462472 |
| dynamic spatiotemporal trends of imported dengue fever in australia. | dengue fever (df) epidemics in australia are caused by infected international travellers and confined to northern queensland where competent vectors exist. recent analyses suggest that global trade and climate change could lead to the re-establishment of ae. aegypti across the country and promote the spread of dengue nationally. this study aimed to describe the dynamic spatiotemporal trends of imported df cases and their origins, identify the current and potential future high-risk regions and lo ... | 2016 | 27460696 |
| additive effect of knockdown resistance mutations, s989p, v1016g and f1534c, in a heterozygous genotype conferring pyrethroid resistance in aedes aegypti in thailand. | mutation in the voltage-gated sodium channel gene that results in knockdown resistance (kdr), is a major mechanism of pyrethroid resistance in several mosquito species. in aedes aegypti, v1016g (occurring with and without s989p) and f1534c mutations are common and widely distributed throughout asia. the g1016 allele is known to be associated with resistance to type i and ii pyrethroids. the c1534 allele is primarily associated with resistance to type i pyrethroids and is known to be a recessive ... | 2016 | 27460671 |
| heat sensitivity of wmel wolbachia during aedes aegypti development. | the wmel strain of wolbachia bacteria is known to prevent dengue and zika virus transmission in the mosquito vector aedes aegypti. accordingly, the release of wmel-infected a. aegypti in endemic regions has been recommended by the world health organization as a potential strategy for controlling dengue and zika outbreaks. however, the utility of this approach could be limited if high temperatures in the aquatic habitats where a. aegypti develop are detrimental to wolbachia. we exposed wmel-infec ... | 2016 | 27459519 |
| a sequence of flushing and drying of breeding habitats of aedes aegypti (l.) prior to the low dengue season in singapore. | in dengue-endemic areas, transmission shows both a seasonal and interannual variability. to investigate how rainfall impacts dengue seasonality in singapore, we carried out a longitudinal survey in the geylang neighborhood from august 2014 to august 2015. the survey comprised of twice-weekly random inspections to outdoor breeding habitats and continuous monitoring for positive ones. in addition, observations of rainstorms were collected. out of 6824 inspected habitats, 67 contained aedes aegypti ... | 2016 | 27459322 |
| ecotoxicological assessment of pyriproxyfen under environmentally realistic exposure conditions of integrated vector management for aedes aegypti control in brazil. | there is increasing concern to control aedes aegypti mosquito exposure in developing countries such as brazil. thus, integrated approaches using a combination of chemical, pyriproxyfen larvicide, and biological, xiphophorus maculatus, larvivorous fish species approaches are necessary and important to initiate more effective control against mosquito borne diseases. this study describes the toxicological effects of pyriproxyfen larvicide on the fish xiphophorus maculatus, the larvivorous fish spec ... | 2016 | 27458879 |
| opposing roles for dna replication initiator proteins orc1 and cdc6 in control of cyclin e gene transcription. | newly born cells either continue to proliferate or exit the cell division cycle. this decision involves delaying expression of cyclin e that promotes dna replication. orc1, the origin recognition complex (orc) large subunit, is inherited into newly born cells after it binds to condensing chromosomes during the preceding mitosis. we demonstrate that orc1 represses cyclin e gene (ccne1) transcription, an e2f1 activated gene that is also repressed by the retinoblastoma (rb) protein. orc1 binds to r ... | 2016 | 27458800 |
| characterization of a midgut mucin-like glycoconjugate of lutzomyia longipalpis with a potential role in leishmania attachment. | leishmania parasites are transmitted by phlebotomine sand flies and a crucial step in their life-cycle is the binding to the sand fly midgut. laboratory studies on sand fly competence to leishmania parasites suggest that the sand flies fall into two groups: several species are termed "specific/restricted" vectors that support the development of one leishmania species only, while the others belong to so-called "permissive" vectors susceptible to a wide range of leishmania species. in a previous s ... | 2016 | 27457627 |
| the insect-specific palm creek virus modulates west nile virus infection in and transmission by australian mosquitoes. | insect-specific viruses do not replicate in vertebrate cells, but persist in mosquito populations and are highly prevalent in nature. these viruses may naturally regulate the transmission of pathogenic vertebrate-infecting arboviruses in co-infected mosquitoes. following the isolation of the first australian insect-specific flavivirus (isf), palm creek virus (pcv), we investigated routes of infection and transmission of this virus in key australian arbovirus vectors and its impact on replication ... | 2016 | 27457250 |
| the interplay of vaccination and vector control on small dengue networks. | dengue fever is a major public health issue affecting billions of people in over 100 countries across the globe. this challenge is growing as the invasive mosquito vectors, aedes aegypti and aedes albopictus, expand their distributions and increase their population sizes. hence there is an increasing need to devise effective control methods that can contain dengue outbreaks. here we construct an epidemiological model for virus transmission between vectors and hosts on a network of host populatio ... | 2016 | 27457093 |
| purification and characterization of a novel kazal-type trypsin inhibitor from the leech of hirudinaria manillensis. | kazal-type serine proteinase inhibitors are found in a large number of living organisms and play crucial roles in various biological and physiological processes. although some kazal-type serine protease inhibitors have been identified in leeches, none has been reported from hirudinaria manillensis, which is a medically important leech. in this study, a novel kazal-type trypsin inhibitor was isolated from leech h. manillensis, purified and named as bdellin-hm based on the sequence similarity with ... | 2016 | 27455325 |
| viral rna silencing suppression: the enigma of bunyavirus nss proteins. | the bunyaviridae is a family of arboviruses including both plant- and vertebrate-infecting representatives. the tospovirus genus accommodates plant-infecting bunyaviruses, which not only replicate in their plant host, but also in their insect thrips vector during persistent propagative transmission. for this reason, they are generally assumed to encounter antiviral rna silencing in plants and insects. here we present an overview on how tospovirus nonstructural nss protein counteracts antiviral r ... | 2016 | 27455310 |
| infection rates by dengue virus in mosquitoes and the influence of temperature may be related to different endemicity patterns in three colombian cities. | colombia is an endemic country for dengue fever where the four serotypes of virus dengue (denv1-4) circulate simultaneously, and all types are responsible for dengue cases in the country. the control strategies are guided by entomological surveillance. however, heterogeneity in aedic indices is not well correlated with the incidence of the disease in cities such as riohacha, bello and villavicencio. as an alternative, molecular detection of dengue virus in mosquitoes has been proposed as a usefu ... | 2016 | 27455289 |
| de novo assembly and characterization of the transcriptome of grasshopper shirakiacris shirakii. | the grasshopper shirakiacris shirakii is an important agricultural pest and feeds mainly on gramineous plants, thereby causing economic damage to a wide range of crops. however, genomic information on this species is extremely limited thus far, and transcriptome data relevant to insecticide resistance and pest control are also not available. | 2016 | 27455245 |
| selective factors associated with the evolution of codon usage in natural populations of arboviruses. | arboviruses (arthropod borne viruses) have life cycles that include both vertebrate and invertebrate hosts with substantial differences in vector and host specificity between different viruses. most arboviruses utilize rna for their genetic material and are completely dependent on host trnas for their translation, suggesting that virus codon usage could be a target for selection. in the current study we analyzed the relative synonymous codon usage (rscu) patterns of 26 arboviruses together with ... | 2016 | 27455096 |
| correlation study between platelet count, leukocyte count, nonhemorrhagic complications, and duration of hospital stay in dengue fever with thrombocytopenia. | dengue is one of the common diseases presenting as fever with thrombocytopenia, also causing significant morbidity and complications. | 0 | 27453855 |
| determination and characterization of destruxin production in metarhizium anisopliae tk6 and formulations for aedes aegypti mosquitoes control at the field level. | destruxins, cyclic hexadepsipeptide toxins, secreted by the entomopathogenic fungus, metarhizium anisopliae through extracellular synthesis. the present study reports a new approach for the analysis of dtxs produced by the fungal strain metarhizium anisoliae tk6, using frir-hplc-lc-ms and h(1) nmr. the results also showed that production of the major dtxs a, b, c, and e have to be determined in czapek dextrose (cd) liquid culture filtrate from 9 to 12 days post-inoculation. purified dtx were fur ... | 2016 | 27452930 |
| the epidemiology and transmissibility of zika virus in girardot and san andres island, colombia, september 2015 to january 2016. | transmission of zika virus (zikv) was first detected in colombia in september 2015. as of april 2016, colombia had reported over 65,000 cases of zika virus disease (zvd). we analysed daily surveillance data of zvd cases reported to the health authorities of san andres and girardot, colombia, between september 2015 and january 2016. zvd was laboratory-confirmed by reverse transcription-polymerase chain reaction (rt-pcr) in the serum of acute cases within five days of symptom onset. we use daily i ... | 0 | 27452806 |
| synthesis and biological evaluation of 3,5-dimethoxystilbene analogs. | in our continuing effort to discover natural product-based pest management agents, derivatives of 3,5-dimethoxystilbene were synthesized yielding 27 new and six known compounds. compounds 11 and 12 showed strong aedes aegypti larvicidal activity (lc50 45.31 and 49.93 μm, respectively). furthermore, 11 and 12 exhibited high effectiveness against larvae of pesticide-susceptible and pyrethroid-resistant strains of ae. aegypti; activity against the adult mosquitoes was low. compounds 6f, 6g, and 6i ... | 2016 | 27450661 |
| a detailed comparative analysis of codon usage bias in zika virus. | zika virus (zikv) is a member of the family flaviviridae and its genome consists of a single-stranded positive sense rna molecule with 10,794 nucleotides. clinical manifestations of disease caused by zikv infection range from asymptomatic cases to an influenza-like syndrome. there is an increasing concern about the possible relation among microcephaly and zikv infection. to get insight into the relation of codon usage among viruses and their hosts is extremely important to understand virus survi ... | 2016 | 27449601 |
| synthesis and insecticidal activity of novel pyrimidine derivatives containing urea pharmacophore against aedes aegypti. | aedes aegypti is a major mosquito vector for the transmission of serious diseases, especially dengue and yellow fever. more than 1 billion people in developing countries are at risk. the widespread and continual use of pesticides can lead to resistant mosquitoes. in order to maintain mosquito control gains, it is critical to develop and evaluate novel bioactive molecules that differ in mode of action from currently used products. | 2017 | 27448764 |
| limited specificity in the injury and infection priming against bacteria in aedes aegypti mosquitoes. | injury and infection priming has been observed in several insect groups, reported as host immune protection against contact with a pathogen caused by a previous infection with the same. however, the specific response against a pathogen has not been demonstrated in all insect species. investigating the specific priming response in insects is important because their immune strategies probably reflect particular selective pressures exerted by different pathogens. here, we determined whether previou ... | 2016 | 27446016 |
| neuroethology of olfactory-guided behavior and its potential application in the control of harmful insects. | harmful insects include pests of crops and storage goods, and vectors of human and animal diseases. throughout their history, humans have been fighting them using diverse methods. the fairly recent development of synthetic chemical insecticides promised efficient crop and health protection at a relatively low cost. however, the negative effects of those insecticides on human health and the environment, as well as the development of insect resistance, have been fueling the search for alternative ... | 2016 | 27445858 |
| lmcyp4g102: an oenocyte-specific cytochrome p450 gene required for cuticular waterproofing in the migratory locust, locusta migratoria. | cytochrome p450 superfamily proteins play important roles in detoxification of xenobiotics and during physiological and developmental processes. to contribute to our understanding of this large gene family in insects, we have investigated the function of the cytochrome p450 gene lmcyp4g102 in the migratory locust locusta migratoria. suppression of lmcyp4g102 expression by rna interference (rnai) does not interfere with moulting but causes rapid loss of body weight - probably due to massive loss ... | 2016 | 27444410 |
| physical influence on larvicidal and pupicidal activity of the silicone-based monomolecular film. | although silicone-based monomolecular film (mmf) has been accepted as larvicide in several countries, its mosquito control potential has never been investigated in thailand. laboratory assessment in this study was conducted to determine the mmf efficacy against aedes aegypti. at the recommended dosage (1ml/m(2) of water surface), mortality of pupae (99.17±0.83%) was significantly greater than mortality of old and young larvae (73.33±9.13, 11.67±3.47%; respectively). pupicidal activity was rapidl ... | 2016 | 27443608 |
| anti-dengue efficacy of bioactive andrographolide from andrographis paniculata (lamiales: acanthaceae) against the primary dengue vector aedes aegypti (diptera: culicidae). | the current study investigated the toxic effect of the leaf extract compound andrographolide from andrographis paniculata (burm.f) against the dengue vector ae. aegypti. gc-ms analysis revealed that andrographolide was recognized as the major chemical constituent with the prominent peak area compared with other compounds. all isolated toxic compounds were purified and confirmed through rp-hplc against chemical standards. the larvicidal assays established at 25ppm of bioactive compound against th ... | 2016 | 27443607 |
| gene expression analysis of overwintering mountain pine beetle larvae suggests multiple systems involved in overwintering stress, cold hardiness, and preparation for spring development. | cold-induced mortality has historically been a key aspect of mountain pine beetle, dendroctonus ponderosae hopkins (coleoptera: curculionidae), population control, but little is known about the molecular basis for cold tolerance in this insect. we used rna-seq analysis to monitor gene expression patterns of mountain pine beetle larvae at four time points during their overwintering period-early-autumn, late-autumn, early-spring, and late-spring. changing transcript profiles over the winter indica ... | 2016 | 27441109 |
| identification of a diazinon-metabolizing glutathione s-transferase in the silkworm, bombyx mori. | the glutathione s-transferase superfamily play key roles in the metabolism of numerous xenobiotics. we report herein the identification and characterization of a novel glutathione s-transferase in the silkworm, bombyx mori. the enzyme (bmgstu2) conjugates glutathione to 1-chloro-2,4-dinitrobenzene, as well as metabolizing diazinon, one of the organophosphate insecticides. quantitative reverse transcription-polymerase chain reaction analysis of transcripts demonstrated that bmgstu2 expression was ... | 2016 | 27440377 |
| expression patterns, mutation detection and rna interference of rhopalosiphum padi voltage-gated sodium channel genes. | the voltage-gated sodium channel (vgsc) is the target of sodium-channel-blocking insecticides. traditionally, animals were thought to have only one vgsc gene comprising a α-subunit with four homologous domains (di-div). the present study showed that rhopalosiphum padi, an economically important crop pest, owned a unique heterodimeric vgsc (h1 and h2 subunits) encoded by two genes (rpvgsc1 and rpvgsc2), which is unusual in insects and other animals. the open reading frame (orf) of rpvgsc1 consist ... | 2016 | 27439594 |
| historical environmental change in africa drives divergence and admixture of aedes aegypti mosquitoes: a precursor to successful worldwide colonization? | increasing globalization has promoted the spread of exotic species, including disease vectors. understanding the evolutionary processes involved in such colonizations is both of intrinsic biological interest and important to predict and mitigate future disease risks. the aedes aegypti mosquito is a major vector of dengue, chikungunya and zika, the worldwide spread of which has been facilitated by ae. aegypti's adaption to human-modified environments. understanding the evolutionary processes invo ... | 2016 | 27439067 |
| leukemoid reaction in chikungunya fever. | chikungunya is a viral illness caused by an arbovirus which is transmitted by aedes mosquito. fever and polyarthralgia are hallmark of this viral illness. viral infections are generally associated with leucopenia and bacterial infections with leukocytosis. leukemoid reaction (lr) is defined by reactive increase in leukocyte count of more than 50,000/cu mm with increase in mature leukocytes on peripheral blood. leukocytosis is common in chikungunya but leukemoid reaction has not been reported in ... | 2016 | 27437276 |
| seasonal and geographical variation of dengue vectors in narathiwat, south thailand. | using gis-based land use map for the urban-rural division (the relative ratio of population density adjusted to relatively aedes-infested land area), we demonstrated significant independent observations of seasonal and geographical variation of aedes aegypti and aedes albopictus vectors between muang narathiwat district (urban setting) and neighbor districts (rural setting) of narathiwat, southern thailand, based on binomial distribution of aedes vectors in water-holding containers (water storag ... | 2016 | 27437001 |
| outbreak of zika virus infection, chiapas state, mexico, 2015, and first confirmed transmission by aedes aegypti mosquitoes in the americas. | after decades of obscurity, zika virus (zikv) has spread through the americas since 2015 accompanied by congenital microcephaly and guillain-barré syndrome. although these epidemics presumably involve transmission by aedes aegypti, no direct evidence of vector involvement has been reported, prompting speculation that other mosquitoes such as culex quinquefasciatus could be involved. | 2016 | 27436433 |
| vaccines and immunization strategies for dengue prevention. | dengue is currently the most significant arboviral disease afflicting tropical and sub-tropical countries worldwide. dengue vaccines, such as the multivalent attenuated, chimeric, dna and inactivated vaccines, have been developed to prevent dengue infection in humans, and they function predominantly by stimulating immune responses against the dengue virus (denv) envelope (e) and nonstructural-1 proteins (ns1). of these vaccines, a live attenuated chimeric tetravalent denv vaccine developed by sa ... | 2016 | 27436365 |
| culex pipiens and aedes triseriatus mosquito susceptibility to zika virus. | 2016 | 27434194 | |
| application of copper-based ovitraps in local houses in west sumatra, indonesia: a field test of a simple and affordable larvicide for mosquito control. | the application of oviposition traps (ovitraps) is one of the currently available rational methods used in mosquito control campaigns because it eliminates the larval stage. however, the use of current larvicides is hampered by their cost and applicability. therefore, a more economical and practical alternative is urgently needed. we previously reported that copper in liquid form is a promising candidate due to its potent larvicide properties in a laboratory setting, affordability, and availabil ... | 2016 | 27433130 |
| thymosin from bombyx mori is down-regulated in expression by bmnpv exhibiting antiviral activity. | thymosins have been highly conserved during evolution. these hormones exist in many animal species and play an essential role in many biological events. however, little is known regarding the physiological function of silkworm bombyx mori thymosin (bmthy). in this study, we investigated the expression pattern of bmthy in a bombyx mori larval ovarian cell line (bmn) challenged with bombyx mori nuclear polyhydrosis virus (bmnpv) and the antiviral effect of recombinant bmthy (rbmthy) for bombyx mor ... | 2016 | 27432352 |
| rna encapsidation and packaging in the phleboviruses. | the bunyaviridae represents the largest family of segmented rna viruses, which infect a staggering diversity of plants, animals, and insects. within the family bunyaviridae, the phlebovirus genus includes several important human and animal pathogens, including rift valley fever virus (rvfv), severe fever with thrombocytopenia syndrome virus (sftsv), uukuniemi virus (uukv), and the sandfly fever viruses. the phleboviruses have small tripartite rna genomes that encode a repertoire of 5-7 proteins. ... | 2016 | 27428993 |
| who is vulnerable to dengue fever? a community survey of the 2014 outbreak in guangzhou, china. | unprecedented dengue fever (df) outbreaks impel china to develop useful disease control strategies. integrated vector management (ivm) focuses on identifying vulnerable populations and interrupting human-vector contact; however, vulnerable populations have not been clearly identified in china. we conducted a case-control study during the initial stage of the 2014 df outbreak in guangzhou, china to assess risk factors for df infection. cases were randomly sampled from the national notifiable infe ... | 2016 | 27428986 |
| effect of spatial repellent exposure on dengue vector attraction to oviposition sites. | aedes aegypti is a primary vector of dengue virus (denv), the causative agent of dengue fever, an arthropod-borne disease of global importance. although a vaccine has been recommended for prevention, current dengue prevention strategies rely on vector control. recently, volatile pyrethroids-spatial repellents-have received interest as a novel delivery system for adult ae. aegypti control. understanding the full range of behavioral effects spatial repellents elicit in mosquito species will be cri ... | 2016 | 27428011 |
| a transgenic approach for controlling lygus in cotton. | lygus species of plant-feeding insects have emerged as economically important pests of cotton in the united states. these species are not controlled by commercial bacillus thuringiensis (bt) cotton varieties resulting in economic losses and increased application of insecticide. previously, a bt crystal protein (cry51aa2) was reported with insecticidal activity against lygus spp. however, transgenic cotton plants expressing this protein did not exhibit effective protection from lygus feeding dama ... | 2016 | 27426014 |
| two novel epistatic mutations (e1:k211e and e2:v264a) in structural proteins of chikungunya virus enhance fitness in aedes aegypti. | expansion of chikv outbreaks with appearance of novel mutations are reported from many parts of the world. two novel mutations viz. e1:k211e and e2:v264a in background of e1:226a are recently identified from aedes aegypti dominated areas of india. in this study, the role of these mutations in modulation of infectivity, dissemination and transmission by two different aedes species was studied. mutations were sequentially constructed in chikv genome and female ae. aegypti and aedes albopictus mosq ... | 2016 | 27423270 |
| experiences with insecticide-treated curtains: a qualitative study in iquitos, peru. | dengue is an arthropod-borne viral disease responsible for approximately 400 million infections annually; the only available method of prevention is vector control. it has been previously demonstrated that insecticide treated curtains (itcs) can lower dengue vector infestations in and around houses. as part of a larger trial examining whether itcs could reduce dengue transmission in iquitos, peru, the objective of this study was to characterize the participants' experience with the itcs using qu ... | 2016 | 27422403 |
| time to empower release of insects carrying a dominant lethal and wolbachia against zika. | ridl (release of insects with dominant lethality) and wolbachia are 2 potentially powerful tools in the fight against zika, but their technological advancement is being hampered by policy barriers. in this study, we discuss what could be done to overcome these regulatory deadlocks. | 2016 | 27419175 |
| resistance status to the insecticides temephos, deltamethrin, and diflubenzuron in brazilian aedes aegypti populations. | insecticides are still largely applied in public health to control disease vectors. in brazil, organophosphates (op) and pyrethroids (py) are used against aedes aegypti for years. since 2009 insect growth regulators (igr) are also employed in the control of larvae. we quantified resistance to temephos (op), deltamethrin (py), and diflubenzuron (igr) of a. aegypti samples from 12 municipalities distributed throughout the country, collected between 2010 and 2012. high levels of resistance to neuro ... | 2016 | 27419140 |
| the effects of interspecific courtship on the mating success of aedes aegypti and aedes albopictus (diptera: culicidae) males. | satyrization, a form of asymmetric reproductive interference, has recently been shown to play a role in competitive displacements of aedes aegypti (l.) by aedes albopictus (skuse). furthermore, female ae. aegypti from populations in sympatry with ae. albopictus have evolved reproductive character displacement and changes in mating behavior to reduce interspecific mating. in this article, we examine evolutionary responses of males to interspecific mating and show that satyrization has also evoked ... | 2015 | 27418696 |
| apoptosis-related genes control autophagy and influence denv-2 infection in the mosquito vector, aedes aegypti. | the mosquito aedes aegypti is the primary urban vector for dengue virus (denv) worldwide. insight into interactions occurring between host and pathogen is important in understanding what factors contribute to vector competence. however, many of the molecular mechanisms for vector competence remain unknown. our previous global transcriptional analysis suggested that differential expression of apoptotic proteins is involved in determining refractoriness vs susceptibility to denv-2 infection in ae. ... | 2016 | 27418459 |
| assessment of the ability of aedes species mosquitoes to transmit feline mycoplasma haemofelis and 'candidatus mycoplasma haemominutum'. | the objective of this study was to evaluate wild-caught mosquitoes for evidence of hemotropic mycoplasma species dna and to determine whether the feline hemoplasmas, mycoplasma haemofelis (mhf) and 'candidatus mycoplasma haemominutum' (mhm), can be transmitted by aedes aegypti mosquitoes in a laboratory setting. | 2016 | 27418288 |
| receptors are affected by selection with each bacillus thuringiensis israelensis cry toxin but not with the full bti mixture in aedes aegypti. | bacillus thuringiensis israelensis (bti) toxins are increasingly used for mosquito control, but little is known about the precise mode of action of each of these toxins, and how they interact to kill mosquito larvae. by using rna sequencing, we investigated change in gene transcription level and polymorphism variations associated with resistance to each bti cry toxin and to the full bti toxin mixture in the dengue vector aedes aegypti. the up-regulation of genes related to chitin metabolism in a ... | 2016 | 27418233 |
| tyrosine hydroxylase is crucial for maintaining pupal tanning and immunity in anopheles sinensis. | tyrosine hydroxylase (th), the initial enzyme in the melanin pathway, catalyzes tyrosine conversion into dopa. although expression and regulation of th have been shown to affect cuticle pigmentation in insects, no direct functional studies to date have focused on the specific physiological processes involving the enzyme during mosquito development. in the current study, silencing of asth during the time period of continuous high expression in anopheles sinensis pupae led to significant impairmen ... | 2016 | 27416870 |
| larval application of sodium channel homologous dsrna restores pyrethroid insecticide susceptibility in a resistant adult mosquito population. | mosquitoes host and pass on to humans a variety of disease-causing pathogens such as infectious viruses and other parasitic microorganisms. the emergence and spread of insecticide resistance is threatening the effectiveness of current control measures for common mosquito vector borne diseases, such as malaria, dengue and zika. therefore, the emerging resistance to the widely used pyrethroid insecticides is an alarming problem for public health. herein we demonstrated the use of rna interference ... | 2016 | 27416771 |
| applications of a rapid and sensitive dengue duo rapid immunochromatographic test kit as a diagnostic strategy during a dengue type 2 epidemic in an urban city. | dengue infection is a major health problem in tropical and subtropical countries. a prospective observational study in a university-affiliated hospital was conducted between august 2015 and september 2015. patients who visited the emergency department (ed) with a presentation of any symptoms of dengue were eligible for the dengue non-structural protein 1 (ns1), igm/igg rapid immunochromatographic tests and real-time polymerase chain reaction (rt-pcr) to evaluate the performance of the rapid test ... | 2016 | 27415767 |
| inhibitor designing, virtual screening, and docking studies for methyltransferase: a potential target against dengue virus. | aim of this work was to design and identify some s-adenosyl-l-homocysteine (sah) analogs as inhibitors of s-adenosyl-l-methionine-dependent methyltransferase (mtase) protein using computational approaches. | 0 | 27413346 |
| larval food quantity affects the capacity of adult mosquitoes to transmit human malaria. | adult traits of holometabolous insects are shaped by conditions experienced during larval development, which might impact interactions between adult insect hosts and parasites. however, the ecology of larval insects that vector disease remains poorly understood. here, we used anopheles stephensi mosquitoes and the human malaria parasite plasmodium falciparum, to investigate whether larval conditions affect the capacity of adult mosquitoes to transmit malaria. we reared larvae in two groups; one ... | 0 | 27412284 |
| molecular diversity between salivary proteins from new world and old world sand flies with emphasis on bichromomyia olmeca, the sand fly vector of leishmania mexicana in mesoamerica. | sand fly saliva has been shown to have proteins with potent biological activities, salivary proteins that can be used as biomarkers of vector exposure, and salivary proteins that are candidate vaccines against different forms of leishmaniasis. sand fly salivary gland transcriptomic approach has contributed significantly to the identification and characterization of many of these salivary proteins from important leishmania vectors; however, sand fly vectors in some regions of the world are still ... | 2016 | 27409591 |
| proceedings of the 3rd ipleiria's international health congress : leiria, portugal. 6-7 may 2016. | 2016 | 27409075 | |
| vector databank in the indian armed forces. | medical intelligence of disease vectors deals with understanding vector distribution and control. | 2011 | 27408077 |
| a laboratory investigation into oviposition responses of aedes aegypti to some common household substances and water from conspecific larvae. | the surveillance of dengue vector - aedes aegypti, is routinely done by using ovitraps (a dark container filled with water and a wooden paddle/towel cloth provided as a oviposition substrate), which indicates the extent of aedes activity in an area. | 2011 | 27407765 |
| transfer of dna from bacteria to eukaryotes. | historically, the members of the agrobacterium genus have been considered the only bacterial species naturally able to transfer and integrate dna into the genomes of their eukaryotic hosts. yet, increasing evidence suggests that this ability to genetically transform eukaryotic host cells might be more widespread in the bacterial world. indeed, analyses of accumulating genomic data reveal cases of horizontal gene transfer from bacteria to eukaryotes and suggest that it represents a significant fo ... | 2016 | 27406565 |
| efficacy of thai neem oil against aedes aegypti (l.) larvae. | trees with larvicidal activity may be found in thailand. we conducted this study to evaluate the efficacy and length of efficacy of thai neem (azadirachta siamensis) oil emulsion and an alginate bead of thai neem oil formulation against early fourth stage aedes aegypti larvae using a dipping test. the thai neem oil emulsion had significantly greater larvicidal activity than the alginate bead formulation at 12 to 60 hours post-exposure (p < 0.01). the thai neem oil formulation resulted in 100% mo ... | 2016 | 27405123 |
| pathogenesis of zika virus-associated embryopathy. | a strong causal association has become evident between zika virus (zikv) infection during pregnancy and the occurrence of fetal growth restriction, microcephaly and eye defects. circumstantial evidence is presented in this paper in support of the hypothesis that these effects, as well as the guillain-barré syndrome, are due to an endogenous form of hypervitaminosis a resulting from zikv infection-induced damage to the liver and the spillage of stored vitamin a compounds ("retinoids") into the ma ... | 2016 | 27403405 |
| composition and genetic diversity of mosquitoes (diptera: culicidae) on islands and mainland shores of kenya's lakes victoria and baringo. | the lake baringo and lake victoria regions of kenya are associated with high seroprevalence of mosquito-transmitted arboviruses. however, molecular identification of potential mosquito vector species, including morphologically identified ones, remains scarce. to estimate the diversity, abundance, and distribution of mosquito vectors on the mainland shores and adjacent inhabited islands in these regions, we collected and morphologically identified adult and immature mosquitoes and obtained the co ... | 2016 | 27402888 |
| egg and fourth instar larvae gut of aedes aegypti as a source of stem cells. | according to the world health organization, 2015 registered more than 1.206.172 cases of dengue in the americas. recently, the aedes aegypti has been not only related to dengue, but also with cases of zika virus and chikungunya. due to its epidemiological importance, this study characterized the morphology of the embryonated eggs of a. aegypti and provided a protocol to culture stem cells from eggs and digestive tract of fourth instar larvae in order to examine cell biology and expression of mar ... | 2016 | 27401144 |
| yellow fever remains a potential threat to public health. | yellow fever (yf) remains a serious public health threat in endemic countries. the recent re-emergence in africa, initiating in angola and spreading to democratic republic of congo and uganda, with imported cases in china and kenya is of concern. there is such a shortage of yf vaccine in the world that the world health organization has proposed the use of reduced doses (1/5) during emergencies. in this short communication, we discuss these and other problems including the risk of spread of yf to ... | 2016 | 27400066 |
| expression and characterization of yeast derived chikungunya virus like particles (chik-vlps) and its evaluation as a potential vaccine candidate. | chikungunya virus (chikv) has emerged as a global health concern due to its recent spread in both old and new world. so far, no chikv specific drug or vaccine is licensed for human use. in this study, we report production of chikungunya virus like particles (chik-vlps) using novel yeast expression system (pichia pastoris) and its evaluation as vaccine candidate. the gene encoding structural polyprotein of chikv from a recent epidemic strain was cloned into yeast expression system. the multicopy ... | 2016 | 27399001 |
| human antibody response to dengue virus: implications for dengue vaccine design. | dengue, a global health threat, is a leading cause of morbidity and mortality in most tropical and subtropical countries. dengue can range from asymptomatic, relatively mild dengue fever to severe and life-threatening dengue hemorrhagic fever. disease severity and outcome is largely associated with the host immune response. several candidate vaccines in clinical trials appear promising as effective measures for dengue disease control. vaccine development has been hampered by safety and efficacy ... | 2016 | 27398060 |
| zika virus infections: an overview of current scenario. | zika virus (zikv) was discovered more than half a century ago, recently it has gained unprecedented attention by the global health community. until 2007, only 14 cases of human zikv infections were reported around the globe, while during the current outbreak, estimated cases mounted to approximately 1.5 million in brazil alone, the virus was disseminated to wider south-american territories and travel-associated zikv infections were reported in usa, europe and recently in china. zikv infections r ... | 2016 | 27393087 |
| serotype influences on dengue severity: a cross-sectional study on 485 confirmed dengue cases in vitória, brazil. | dengue is caused by a rna virus of the family flaviviridae, which presents four serotypes (denv-1 to denv-4) capable of inducing hemorrhage. the purpose of this study was to evaluate the influence of serotype on the outcome of dengue. | 2016 | 27393011 |
| using stable isotopes of carbon and nitrogen to mark wild populations of anopheles and aedes mosquitoes in south-eastern tanzania. | marking wild mosquitoes is important for understanding their ecology, behaviours and role in disease transmission. traditional insect marking techniques include using fluorescent dyes, protein labels, radioactive labels and tags, but such techniques have various limitations; notably low marker retention and inability to mark wild mosquitoes at source. stable isotopes are gaining wide spread use for non-invasive marking of arthropods, permitting greater understanding of mosquito dispersal and res ... | 2016 | 27392083 |
| mosquitocidal effect of glycosmis pentaphylla leaf extracts against three mosquito species (diptera: culicidae). | the resistance status of malaria vectors to different classes of insecticides used for public health has raised concern for vector control programmes. alternative compounds to supplement the existing tools are important to be searched to overcome the existing resistance and persistence of pesticides in vectors and the environment respectively. the mosquitocidal effects of glycosmis pentaphylla using different solvents of acetone, methanol, chloroform and ethyl acetate extracts against three medi ... | 2016 | 27391146 |
| competitive advantage of a dengue 4 virus when co-infecting the mosquito aedes aegypti with a dengue 1 virus. | dengue viruses (denv) are comprised in four related serotypes (denv-1 to 4) and are critically important arboviral pathogens affecting human populations in the tropics. south american countries have seen the reemergence of denv since the 1970's associated with the progressive re-infestation by the mosquito vector, aedes aegypti. in french guiana, denv is now endemic with the co-circulation of different serotypes resulting in viral epidemics. between 2009 and 2010, a predominant serotype change o ... | 2016 | 27390932 |
| epidemiological risk factors for adult dengue in singapore: an 8-year nested test negative case control study. | understanding changes in the ecology and epidemiology of dengue is important to ensure resource intensive control programmes are targeted effectively as well as to inform future dengue vaccination strategies. | 2016 | 27390842 |
| metarhizium brunneum blastospore pathogenesis in aedes aegypti larvae: attack on several fronts accelerates mortality. | aedes aegypti is the vector of a wide range of diseases (e.g. yellow fever, dengue, chikungunya and zika) which impact on over half the world's population. entomopathogenic fungi such as metarhizium anisopliae and beauveria bassiana have been found to be highly efficacious in killing mosquito larvae but only now are the underlying mechanisms for pathogenesis being elucidated. recently it was shown that conidia of m. anisopliae caused stress induced mortality in ae. aegypti larvae, a different mo ... | 2016 | 27389584 |
| vector competence of northern european culex pipiens biotypes and hybrids for west nile virus is differentially affected by temperature. | outbreaks of west nile virus (wnv) have not occurred in northern europe despite nearby circulation of wnv in the southern part of the continent. the main vector for wnv, the mosquito culex (cx.) pipiens, consists of two behaviorally distinct biotypes, pipiens and molestus, which can form hybrids. although temperature has been shown to influence vector competence of cx. pipiens for wnv and biotypes are differentially susceptible towards infection, the interaction between the two has not been eluc ... | 2016 | 27388451 |
| mosquito communities and disease risk influenced by land use change and seasonality in the australian tropics. | anthropogenic land use changes have contributed considerably to the rise of emerging and re-emerging mosquito-borne diseases. these diseases appear to be increasing as a result of the novel juxtapositions of habitats and species that can result in new interchanges of vectors, diseases and hosts. we studied whether the mosquito community structure varied between habitats and seasons and whether known disease vectors displayed habitat preferences in tropical australia. | 2016 | 27388293 |
| particularities of allergy in the tropics. | allergic diseases are distributed worldwide and their risk factors and triggers vary according to geographical and socioeconomic conditions. allergies are frequent in the tropics but aspects of their prevalence, natural history, risk factors, sensitizers and triggers are not well defined and some are expected to be different from those in temperate zone countries. the aim of this review is to investigate if allergic diseases in the tropics have particularities that deserve special attention for ... | 2016 | 27386040 |
| aedes aegypti (diptera: culicidae) in a tree hole in brazil. | 2017 | 27384845 | |
| diversity of yellow fever mosquito vectors in the atlantic forest of rio de janeiro, brazil. | environmental modifications caused by human activities have led to changes in mosquito vector populations, and sylvatic species have adapted to breeding in urban areas. | 2017 | 27384833 |
| serious disease outbreaks caused by viruses transmitted by aedes aegypti in brazil. | 2017 | 27384820 | |
| [new distribution areas of aedes aegypti in peru]. | 2016 | 27384639 | |
| [suggestions for chikungunya control based on a sensitivity analysis of a mathematical model]. | chikungunya fever seriously affects peoples' health and causes chronic joint pain and even disability. chikungunya is transmitted by the bite of aedes aegypti and aedes albopictus. outbreaks have been reported in throughout the world, including latin america. mathematical modeling studies of these outbreaks have calculated the values of various epidemiological parameters. based on them, a mathematical model was prepared to simulate a chikungunya outbreak in a local population, which was transmi ... | 2016 | 27384636 |
| larvicidal activity of syzygium aromaticum (l.) merr and citrus sinensis (l.) osbeck essential oils and their antagonistic effects with temephos in resistant populations of aedes aegypti. | environmentally friendly botanical larvicides are commonly considered as an alternative to synthetic larvicides against aedes aegypti linn. in addition, mosquito resistance to currently used larvicides has motivated research to find new compounds acting via different mechanisms of action, with the goal of controlling the spread of mosquitos. essential oils have been widely studied for this purpose. this work aims to evaluate the larvicidal potential of syzygium aromaticum and citrus sinensis ess ... | 0 | 27384083 |
| importance of mosquito "quasispecies" in selecting an epidemic arthropod-borne virus. | most arthropod-borne viruses (arboviruses), perpetuated by alternation between a vertebrate host and an insect vector, are likely to emerge through minor genetic changes enabling the virus to adapt to new hosts. in the past decade, chikungunya virus (chikv; alphavirus, togaviridae) has emerged on la réunion island following the selection of a unique substitution in the chikv e1 envelope glycoprotein (e1-a226v) of an east-central-south african (ecsa) genotype conferring a higher transmission rate ... | 2016 | 27383735 |
| juvenile hormone biosynthesis in insects: what is new, what do we know, and what questions remain? | our understanding of jh biosynthesis has significantly changed in the last years. in this review i would like to discuss the following topics: (1) the progresses in understanding the jh biosynthesis pathway. access to genome sequences has facilitated the identification of all the genes encoding biosynthetic enzymes and the completion of comprehensive transcriptional studies, as well as the expression and characterization of recombinant enzymes. now the existence of different flux directionalites ... | 2014 | 27382622 |
| genome sequence of dengue virus 3 from the pythium insidiosum transcriptomes. | 2016 | 27379056 | |
| distribution of aedes mosquitoes in the kilimanjaro region of northern tanzania. | little is known about the presence and distribution of aedes mosquitoes in northern tanzania despite the occurence of viruses transmitted by these mosquitoes such as chikungunya virus (chikv) and dengue virus (denv) in the region. adult and larval mosquitoes were collected from rural and urban settings across a wide range of altitudes in the kilimanjaro region using the mosquito magnet co2 trap for collection of adults and old tires for breeding of larvae. polymerase chain reaction assays were p ... | 2016 | 27376502 |
| modulation of the behavioral and electrical responses to the repellent deet elicited by the pre-exposure to the same compound in blattella germanica. | insects under different stimuli from the environment modify behavioural responses due to changes in the sensitivity of neurons at the peripheral and/or at the central level of the nervous system. this phenomenon is called neuronal plasticity, and sensory adaptation is an example of it. an insect repellent is a chemical that produces oriented movements of the insects away from its source. in this work we studied the modulation of the behavioural and electrical response to the repellent n, n-dieth ... | 2016 | 27375967 |
| insulin receptor-like ectodomain genes and splice variants are found in both arthropods and human brain cdna. | truncated receptor ectodomains have been described for several classes of cell surface receptors, including those that bind to growth factors, cytokines, immunoglobulins, and adhesion molecules. soluble receptor isoforms are typically generated by proteolytic cleavage of the cell surface receptor or by alternative splicing of rna transcripts arising from the same gene encoding the full-length receptor. both the epidermal growth factor receptor (egfr) and the insulin receptor (insr) families prod ... | 2013 | 27375681 |