Publications

comparison of beta enolase and myoglobin as histological markers of rhabdomyosarcoma.	a comparative study of beta enolase and myoglobin as markers of muscle differentiation in rhabdomyosarcoma was carried out, using an immunoperoxidase peroxidase antiperoxidase technique. material from 26 cases of childhood rhabdomyosarcoma was studied and subdivided into embryonal and alveolar types. positive cytoplasmic staining for beta enolase was seen in 85% of tumours studied (91% alveolar, 79% embryonal), whereas positive staining for myoglobin was detected in only 69% of tumours (82% alve ...	2013	3905869
flow cytometric analysis of tetanus toxin binding to neuroblastoma cells.	a neuroblastoma cell line was assessed for its capacity to bind tetanus toxin (tt) by using immunofluorescence and flow cytometry to analyze cells on a single cell basis. a clone of neuro 2a, n2ab-1, was shown to bind variable amounts of tt per cell and this binding could be saturated by increasing doses of the toxin. toxin binding was specific for neuronal cells, as the non-neuronal cell line, c6 glioma, bound negligible amounts of toxin. variability of immunofluorescence staining was due in pa ...	2013	3905830
characterization of monoclonal antibodies against shiga-like toxin from escherichia coli.	three monoclonal antibodies, designated mab 16e6, mab 13c4, and mab 19g8, were produced which recognize shiga-like toxin (slt) from escherichia coli. all three monoclonal antibodies neutralized the cytotoxicity of e. coli slt and were able to immunoprecipitate intact labeled toxin with staphylococcus aureus protein a. the three antibodies were of the g1 heavy and kappa light chain classes. mab 16e6 bound to the b subunit of slt in western blots and also neutralized the lethality of the toxin for ...	1985	3905611
shigellosis (antibiotic resistance and transfer of r-factor).		1985	3900357
plasmid-mediated drug resistance of shigellae in kuwait.	of 153 clinical isolates of shigellae examined, 64.7% belonged to shigella flexneri, 18.9% to sh. sonnei, 11.8% to sh. boydii and 4.6% to sh. dysenteriae. part of these isolates were resistant to sulfamethoxazole and streptomycin (88.2% each), ampicillin (66.7%), tetracycline (63.4%) and co-trimoxazole (43.1%), with levels of resistance (mic50 and mic90) being invariably high. resistance to three or more drugs (multidrug resistance) was seen in 77.8% of the isolates. all the 25 strains examined ...	1985	3899007
transformation of trypomastigote forms of trypanosoma cruzi into activators of alternative complement pathway by immune igg fragments.	in this report we examined the capacity of immune igg fragments to prepare trypomastigote bloodstream forms (tbf) of trypanosoma cruzi for lysis. f(ab')2 fragments were capable of presensitizing tbf for complement (c) lysis, thus excluding the participation of fc domains in the c activation process. an intact hinge region of the igg molecule was not involved either, since the corresponding fab' were almost as active as the original molecules in preparing tbf for lysis. fab also retained such act ...	1985	3898353
transformation of trypomastigote forms of trypanosoma cruzi into activators of alternative complement pathway by immune igg fragments.	in this report we examined the capacity of immune igg fragments to prepare trypomastigote bloodstream forms (tbf) of trypanosoma cruzi for lysis. f(ab')2 fragments were capable of presensitizing tbf for complement (c) lysis, thus excluding the participation of fc domains in the c activation process. an intact hinge region of the igg molecule was not involved either, since the corresponding fab' were almost as active as the original molecules in preparing tbf for lysis. fab also retained such act ...	1985	3898353
scintigraphic diagnosis of hepatic hemangioma: its role in the management of hepatic mass lesions.	hepatic cavernous hemangiomas are benign tumors of the liver that are often an incidental finding. they are usually asymptomatic but may cause symptoms when traumatized, may bleed spontaneously, or may produce pain by virtue of their large size and mass effect. a retrospective analysis of the clinical presentation, liver function tests, and diagnostic imaging procedures in 20 patients with hepatic hemangiomas is presented and the literature is reviewed. the 20 patients had 27 mass lesions as see ...	2014	3895854
enzyme immunoassay of human protein c by using monoclonal antibodies.	an enzyme-linked immunosorbent assay (elisa) for measuring human protein c by using two monoclonal antibodies directed toward the heavy chain of protein c is reported. this assay enabled the determination of protein c in concentrations of 10 to 400 ng/ml in less than 3 hours with a single antigen-antibody reaction. within-run and between-run coefficients of variation were less than 8%. the mean concentrations of protein c in plasma of 42 normal subjects, 24 patients with liver disease, 27 with d ...	1985	3895562
an epidemic of bacillary dysentery at raipur.		1985	3891837
treatment of severe bacillary dysentery with trimethoprim alone.	trimethoprim (300 mg twice daily for five days) and co-trimoxazole (two tablets twice daily for five days) were compared as treatment for adult patients with severe shigellosis in rwanda. excellent bacteriological and clinical results were obtained with both regimens, with the exception of patients infected with a trimethoprim-resistant strain of shigella dysenteriae type 1. since only 20 patients were investigated, the conclusions of our study do not reach statistical significance. before recom ...	1985	3890282
properties of rat liver signal peptidase reconstituted into liposomes.	edta/kcl- or pyrophosphate-treated rough microsomes of rat liver clearly showed the co-translational cleavage of pre-human placental lactogen and translocation of the product into membrane vesicles. the signal peptidase fraction was isolated by chromatography on sephacryl s-300 of deoxycholate-treated membranes and reconstituted into liposomes by dialysis or by the biobeads sm-2 method. assay of the signal peptidase activity was performed with pre-human placental lactogen synthesized by the reti ...	1985	3888971
[role of the conjugative transfer of r-plasmids in competitive interactions between plasmid-containing and plasmid-free strains of escherichia coli in continuous culture].	competition of the plasmid-containing strain c600 (rp4) (pbs94) of e. coli and the plasmid-free strain c600 rifr of e. coli in chemostatic and ph-static continuous cultures resulted in displacement of the plasmid-free strain in spite of its higher specific growth rate. conjugative transfer of rp4 and pbs94 plasmids into the cells of the plasmid-free strain was observed in the experiments. competition of strains c600 (pbs94) (rp4 tra-) and c600 rifr in the chemostatic culture in the absence of th ...	1985	3888095
[diagnosis and documentation of biliary calculi].		2014	3887025
shiga toxin--an expanding role in the pathogenesis of infectious diseases.		1985	3886803
plasmid characterization of drug-resistant shigella dysenteriae 1 from an epidemic in central africa.	a widespread epidemic of severe dysentery in zaire and neighbouring central african countries was caused by a multiply drug-resistant strain of shigella dysenteriae 1. early isolations were resistant to ampicillin, chloramphenicol, streptomycin, sulphonamides and tetracyclines (r-type = acssut). later in the epidemic strains resistant to trimethoprim (tm) became prevalent and a few strains resistant to kanamycin (k) or nalidixic acid were also isolated. all resistances except nalidixic acid were ...	1985	3886782
a new provisional serovar of shigella dysenteriae.	bacterial isolates obtained in israel from stool cultures of 17 sporadic cases of acute diarrhea during the years 1972 to 1980 and from 14 patients involved in an institutional outbreak in 1984 are described. these cultures gave the biochemical reactions and pathogenicity tests characteristics of the genus shigella but failed to agglutinate, living or boiled, in any of the recognized or provisional shigella antisera. all 31 cultures were biochemically and serologically identical, and owing to th ...	1985	3882749
an animal model of haemolytic--uraemic syndrome in shigellosis: lipopolysaccharides of shigella dysenteriae i and s. flexneri produce leucocyte-mediated renal cortical necrosis in rabbits.	to develop an animal model of the haemolytic-uraemic syndrome during shigellosis, rabbits were injected with lipopolysaccharides (lps) extracted by the hot phenol-water method from shigella dysenteriae i and from s. flexneri. two intravenous injections of lps spaced by 24 h elicited renal cortical necrosis in a generalized shwartzman reaction characterized by fibrin deposition in glomerular capillaries and by elevated plasma creatinine concentration. rabbits rendered leucopenic by busulphan trea ...	1985	3882120
cranial ultrasound and clinical studies in preterm infants.	serial ultrasound imaging of the brain was used to determine the ventricular index (vi), and the ratio (vr) of the vi to the cranial hemidiameter during the nursery course and first year post-term in preterm infants of less than 33 weeks gestation. twenty-nine of the infant survivors with no intracranial hemorrhage or major medical complication during their nursery course composed group 1. twenty-two survivors with intracranial hemorrhage unassociated with early ventricular dilation composed gro ...	2013	3881581
addition of three new serotypes of shigella boydii to the shigella schema.	no new serotypes have been added to the shigella schema since 1958, although several provisional serotypes have been described. we conducted biochemical and serological studies on three provisional shigella boydii serotypes. four strains of serotype 2710-54 from four widely separated countries, 7 strains of serotype 3615-53 from three different countries, and 31 strains of serotype 1344-78 (e10163) from six different countries were included. reactions of all three serotypes were consistent with ...	1985	3881469
brain oedema following brain ischaemia and the influence of therapy.		1985	3881111
shiga-like cytotoxin production by enteropathogenic escherichia coli serogroups.	the mechanism by which enteropathogenic escherichia coli (epec) cause disease remains to be defined. we studied epec and non-epec strains of e. coli from stool specimens obtained from infants and adults for production of shiga-like cytotoxin. although it was common for healthy infants and adults to have cytotoxin-producing e. coli as part of the fecal flora, shiga-like cytotoxin was detected more commonly and in greater amounts among epec than among other fecal e. coli. these results suggest a r ...	1985	3880727
[introduction of pos: an educational method. practice of auditing and problems in the application of soap].		2013	3878425
[different clinical and prognostic aspects of angina pectoris in unstable phase].	the purpose of this study was to focus on the clinical and angiographic characteristics of 113 patients with crescendo angina (group i) as compared to 187 patients with angina of new onset (group ii), selected from a series of 474 consecutive subjects, admitted to our clinic between january 1976 and july 1983 because of recurrent episodes of spontaneous angina, who underwent cardiac catheterization and coronary angiography within one month of hospitalization. group i patients showed a greater in ...	1985	3878310
[evaluation of factors influencing patency of a-c bypass grafts].		2013	3877126
quantitation of vanadium oxides in airborne dusts by x-ray diffraction.		2014	3876785
the segmental nephrogram.		2013	3875232
radiographic findings in pulmonary hypertension from unresolved embolism.	pulmonary artery hypertension with chronic pulmonary embolism is an uncommon entity that is potentially treatable with pulmonary embolectomy. although the classic radiographic features have been described, several recent investigators report a significant percentage of these patients with normal chest radiographs. in a series of 22 patients, no normal radiographs were seen. findings included cardiomegaly (86.4%) with right-sided enlargement (68.4%), right descending pulmonary artery enlargement ...	2013	3872021
[dieulafoy disease. a rare cause of upper gastrointestinal hemorrhage].		2013	3871983
[dieulafoy disease. a rare cause of upper gastrointestinal hemorrhage].		2013	3871983
[the development of the human dentition. iv].		1985	3867519
[the development of the human dentition. iv].		1985	3867519
[retinopathia centralis serosa--initial symptom of acute lymphoblastic leukemia].	central serous retinopathy caused a gradual decrease in visual acuity in the left eye of a 14-year-old boy. during a general medical examination systematic investigation revealed an acute lymphoblastic leukemia. as a result of adequate therapy visual acuity improved from 0.1 to 1.0.	2013	3866875
female dentists. a factor in determining the available future dental work force.		2013	3866779
protein loss of bovine dental enamel during in-vitro subsurface demineralization.	a chemical system based on the dialysis principle was used to study protein loss of dental enamel during demineralization with an acetic-acid buffer solution containing calcium and phosphate, in which the fluoride-ion activity was kept constant. this resulted in a subsurface lesion, with a depth of about 130 microns. after demineralization, protein material was isolated from the demineralization solution. u.v. spectra of the protein showed strong absorbance between 240 and 300 nm. amino-acid com ...	1985	3865639
[gingiva width and periodontal health].		2013	3863386
analysis of leukemic cells with monoclonal antibodies in acute myelomonocytic leukemia suggests abnormality at an early differentiation stage in certain cases.		2013	3861479
jcah board of commissioners approves changes regarding medical staff bylaws.		2013	3857212
theoretical mechanisms for synthesis of carcinogen-induced embryonic proteins: xiv. mutational and non-mutational mechanisms as subsets of a more general mechanism. part c. a defined cancer mutation.	the results of applying a mechanism of ethionine-induced embryonic gene derepressions to explain similar features found in hereditary tyrosinemia have been extended to a well defined cancer mutation. in all three cases, the described mechanism is compatible with the explanation for the etiology of embryonic like phenotypic expressions in cells and potentially for the carcinogenic process. the essence of the formulated process for a human bladder carcinoma mutation in the ras gene for a protein p ...	1985	3853079
[communication among the nursing staff for uniform nursing care. proper communication between nursing teams for proper nursing care].		2013	3847715
shigella toxin and the pathogenesis of shigellosis.	shigella dysenteriae 1 produces a periplasmic protein with multiple toxic effects in vivo and in vitro. these include neurotoxicity, cytotoxicity and enterotoxicity, as well as the ability to inhibit cell-free protein synthesis. the purified toxin is a protein of relative molecular mass (mr) 64 000. it is composed of one catalytically active a subunit (mr = 32 000) that inhibits protein synthesis, and a complex of five b monomers (mr approximately 6500 each). studies using subunit-specific antib ...	1985	3847336
financial (care) plan.		2012	3845999
do nurses know when patients have cognitive deficits?		2013	3844431
adolescent sexuality: part one.		2013	3843485
hla and nephropathies in mexican mestizo people.		2013	3842918
aqueous micellar systems in membrane protein crystallization. partial miscibility of a nonionic surfactant in the presence of salt or polyethylene glycol.	the effects of nacl and polyethylene glycol (peg) 4000 on the lower consolution boundary (lcb) of a nonionic surfactant (c8e5) were studied and compared. micellar systems were nacl and peg 4000 are present are often used in membrane protein crystallization. while sodium chloride shifts the surfactant lcb to lower temperatures without a significant change in the shape of the boundary, peg produces a large solubility change strongly depending on the surfactant concentration. the salt effect is exp ...	2013	3840746
[nonocclusive ischemic enteropathy--a rare cause of ileus].	the cause for a nonocclusive ischemic enteropathy seems to be a low cardiac output syndrome. there are often signs of a paralytic intestinal obstruction. parameters of the blood chemistry offer no conclusive data. the angiogram of the mesenteric vessels demonstrates extensive arterial vasoconstriction as well as an obstructed venous outflow. experimental findings disclose that this venous obstruction may be a result of an ischemic contracture in the course of a low flow state. this rigor initiat ...	2013	3840557
4-hydroxyalk-2-enals are substrates for glutathione transferase.	the 4-hydroxyalk-2-enals are established products of lipid peroxidation that are conjugated with intracellular glutathione. cytosolic glutathione transferases from rat liver were shown to give high specific activities with 4-hydroxynonenal and 4-hydroxydecenal. the isoenzyme giving the highest specific activity was glutathione transferase 4-4. the rate of the spontaneous conjugation reaction is negligible in comparison with the rate calculated for the cellular concentration of the glutathione tr ...	1985	3838159
[multiple breast metastasis of cutaneous malignant melanoma].		2013	3838028
[instrumental and bloodless methods of diagnosis of colonic cancer (importance for clinical and therapeutic management].		2013	3838026
the role of the national institute of hygiene in improving public health in hungary.		2013	3837999
hospice: from social movement to health care industry.		2013	3837967
effect of organic components of blood serum on its osmolality.		2013	3837747
assessment of the character and incidence of electrocardiographic changes in children with simple obesity.	the studied group comprised 82 children with simple obesity. in the group the character and frequency of ecg changes in 12 conventional leads were analyzed. a correlation was established between the character and frequency of these changes and the degree of overweight and obesity duration. in children with simple obesity a considerable prevalence was observed of disturbances of sinus rhythm, impairment of intraventricular conduction and signs of left ventricular hypertrophy. the observed changes ...	2009	3837606
assessment of the character and incidence of electrocardiographic changes in children with simple obesity.	the studied group comprised 82 children with simple obesity. in the group the character and frequency of ecg changes in 12 conventional leads were analyzed. a correlation was established between the character and frequency of these changes and the degree of overweight and obesity duration. in children with simple obesity a considerable prevalence was observed of disturbances of sinus rhythm, impairment of intraventricular conduction and signs of left ventricular hypertrophy. the observed changes ...	2009	3837606
[effect of titanium phosphate, zirconium oxide and a mixture of ammonium phosphotungstenate with zirconium phosphate on the elimination of radioactive cesium from the bodies of rats].		1985	3835674
[casein gene].		2011	3834511
a further contribution to the study of the genus penicillium.	a study of one hundred penicillium strains belonging to raper and thom's monoverticillate series was carried out. the data compiled led to the conclusion that there are no significant biochemical differences which would make possible an accurate separation of the strains belonging to the series.	2013	3834278
patient satisfaction with medical students' clinical skills: comparison of randomly selected hospital patients and trained patients.		2013	3834267
perforative peritonitis of appendiceal origin.		2013	3832913
[university clinics: yesterday, today, tomorrow].		2008	3832205
extracorporeal shock-wave lithotripsy and the medical treatment of renal stones.		2013	3831739
stability of pilocarpine ophthalmic formulations.		2013	3829160
[the esophageal mucosal hemodynamics in patients with liver cirrhosis].		2013	3820752
leads from the mmwr. use of supplements containing high-dose vitamin a--new york state, 1983-1984.		2012	3820435
electrocardiographic abnormalities and mortality among middle-aged black men and white men of evans county, georgia.	the distribution of electrocardiographic (ecg) abnormalities and the relationship between ecg abnormalities and mortality after 20 years of follow-up were examined among 40-64-year-old black men and white men enrolled in the evans county heart study. major or minor ecg abnormalities, as defined in the pooling project, were present at entry for 53% of blacks (164 of 308) and 31% of whites (159 of 511). for both races, the presence of ecg abnormalities was directly related to age, blood pressure, ...	2011	3818868
functions of the proteoglycans.		2013	3816413
desirable standards of performance for therapeutic drug monitoring.	therapeutic drug monitoring is an important aspect of clinical chemistry for which no objective analytical goals yet exist. based on fundamental pharmacokinetic theory, and the current consensus strategy for analytical goal-setting for precision based upon biological variation, a theoretical model allows derivation of the goal that: analytical cv less than or equal to 1/4 [(2t/t - 1)/(2t/t + 1)] x 100%, where t is the time interval between doses, and t is the average elimination half-life. using ...	2010	3815803
the incidence and significance of seminal vesicle invasion in patients with adenocarcinoma of the prostate.	the incidence and significance of seminal vesicle invasion in patients with adenocarcinoma of the prostate were determined in 139 patients who underwent radical prostatectomy. of the 36 patients who had seminal vesicle invasion, 27 (75%) also had capsular invasion and 13 (43%) had lymph node metastases. disease progression rates were 31% and 58% at 5 and 8 years, respectively. survival rate at 5 years was 90.6% and at 8 years it was 83.7%. of the 103 patients without seminal vesicle invasion, 21 ...	2009	3815316
fine needle aspiration biopsy in the diagnosis of thyroid cancer and thyroid disease.	fine needle aspiration biopsy (fnab) performed for diffuse and nodular goiter in the past 5 years, was evaluated in 1399 cases. surgery was performed on the basis of fnab cytologic diagnosis that was positive or suggestive of malignancy and/or a suggestive clinical history. surgery also was performed in cases of cold nodules with negative fnab results that did not respond to 6 months of suppressive thyroxine therapy. a correlation of cytologic findings with histologic findings was possible in 41 ...	2008	3815295
the case of the recalcitrant welshman.		2013	3815002
[anatomo-surgical considerations in the treatment of the pancreatic stump in duodeno-cephalo-pancreatectomy].		2013	3813264
diagnostic and curative value of uterine curettage.	one hundred and eighty-one consecutive patients admitted for curettage because of irregular uterine bleeding were classified preoperatively as having postmenopausal bleeding, intermenstrual bleeding, menorrhagia, or metrorrhagia. they were followed up at 3 and 9 months after curettage with regard to diagnosis and cure. fifty-seven per cent were cured; the lowest curative effect was found in patients suffering from menorrhagia. an etiological diagnosis was made in 90 patients; in the menorrhagia ...	2013	3811841
the role of androstenedione and testosterone in the reproduction and antler growth of a male white-tailed deer.	seasonal levels of androstenedione and testosterone were investigated in plasma of mature intact and castrated male white-tailed deer. in four intact bucks, androstenedione concentrations were low in february and march (around 1 nmol/l) and then increased significantly (p less than 0.05) from april to november (peak 2.34 nmol/l). testosterone remained low (below 3.5 nmol/l) from february to august and then rose significantly (p less than 0.01) till november (peak 36.78 nmol/l). both hormones dec ...	2013	3811770
antimicrobial activities of some flavonoid compounds.	6 flavonoid compounds, namely kaempferol, quercetin, myricetin, rutin, naringin, and formononetin were separated from different plant materials. they were identified using column and paper chromatography techniques, and physicochemical methods were applied to determine their structure. isolated flavonoids were tested for their antimicrobial property against different bacterial and fungal strains as test organisms.	2013	3811648
[initial experiences with the cementless pm endoprosthesis].	a follow up of 40 cementless fixed endoprostheses type pm showed good results, similar to cement fixed prostheses. in cementless fixation seem to be more early complications and less late complications, so these results are encouraging what concerns cementless fixation.	2013	3811488
the cutting diathermy and drain tracts.		2013	3810377
meta-analyses of randomized controlled trials.	a new type of research, termed meta-analysis, attempts to analyze and combine the results of previous reports. we found 86 meta-analyses of reports of randomized controlled trials in the english-language literature. we evaluated the quality of these meta-analyses, using a scoring method that considered 23 items in six major areas--study design, combinability, control of bias, statistical analysis, sensitivity analysis, and application of results. only 24 meta-analyses (28 percent) addressed all ...	2013	3807986
pneumonia--the quality of medical records data.	the quality of medical records data for patients who were hospitalized with community-acquired pneumonia was assessed by comparing medical records data with data obtained in a prospective study of pneumonia for the period april 1, 1984, to december 31, 1984. one hundred five patients fulfilled the case definition of pneumonia for entry into the prospective study. one hundred twenty-seven patients were identified by medical records data. seventy-three of the patients appeared in both studies. the ...	1987	3807447
effect of age, sex, and body surface area on echocardiographic left ventricular wall mass in normal subjects.	m-mode echocardiography was used to estimate left ventricular wall mass in 136 older normal subjects (group i: 78 men and 58 women, ages 20 to 97 years) and 105 younger normal subjects (group ii: 52 male and 53 female subjects, ages 1 day to 23 years). echocardiographic left ventricular mass (in grams) was estimated from the following formula: left ventricular mass = 1.05 ([ left ventricular internal diastolic dimension + ventricular septal thickness (diastole) + posterior wall thickness (diasto ...	2013	3804398
effect of clofibrate feeding on some lipogenic enzyme activities induced by high carbohydrate diet.	clofibrate administration by stomach tube or intraperitoneally for 3 successive days to rats fed standard diet or starved for 72 hr caused about 2-fold increase of malic enzyme activity in the liver and adipose tissue. the drug administered by stomach tube (but not intraperitoneally) to the rats fed fat free-high carbohydrate diet significantly blocked the inducing effect of the diet on malic enzyme activity in both tissues. clofibrate blocked the induction by fat free-high carbohydrate diet of ...	1986	3801034
[analysis of the fatal outcomes in falls from a height].		2013	3798496
[glomerulonephritis following infections].		2013	3795528
suppression of free fatty acids and triglycerides in normal and hypertriglyceridemic rats by the adenosine receptor agonist phenylisopropyladenosine.	activation of adenosine receptors leads to the inhibition of lipolysis in the fat cells of several species including humans. we have examined the effects of the adenosine analog phenylisopropyladenosine (pia) on lipolysis in vivo in intact rats. pia suppresses markedly serum-free fatty acid (ffa) concentrations when injected s.c. (-)-pia is more potent than (+)-pia in suppressing ffa concentrations; also, this effect of (-)-pia is blocked by the adenosine receptor antagonist 8-(p-sulfophenyl)the ...	1986	3795036
glucose regulation of cephamycin biosynthesis in streptomyces lactamdurans is exerted on the formation of alpha-aminoadipyl-cysteinyl-valine and deacetoxycephalosporin c synthase.	glucose exerted a concentration-dependent negative regulation on the biosynthesis of cephamycin c by streptomyces lactamdurans. formation of the cephamycin precursor delta(alpha-aminoadipyl)-cysteinyl-valine was greatly decreased by excess glucose. the ring-expanding enzyme deacetoxycephalosporin c synthase was strongly repressed by glucose in vivo. isopenicillin n synthase (cyclase) and isopenicillin n epimerase were not repressed by glucose. however, the activity of isopenicillin n synthase wa ...	1986	3794640
incidence, clinical significance and prognosis of ventricular fibrillation in the early phase of myocardial infarction.	of 1265 patients admitted to the ccu with the diagnosis of acute mi, 96 (7.6%) developed ventricular fibrillation within 72 hours following admission. of these 96, 35 (36.5%) had secondary vf associated with left ventricular failure; they had a high in-hospital mortality of 57.1%. the remaining 61 (63.5%) had primary vf, i.e. vf occurring in the absence of significant lv failure. fourteen of these (23%) died in hospital: 9 due to pvf (3 during the first episode, 6 during a recurrence). this mort ...	2013	3792355
1h-nmr assignments and the dynamics of interconversion of the isomeric forms of cytochrome b5 in solution.	cytochrome b5 reconstituted with specifically deuterated hemins has led to the assignment of the resolved 6,7 beta-propionate protons and heme meso protons. freshly reconstituted cytochrome b5 contains a mixture of two isomers in an approx. 1:1 ratio. as time proceeds the minor isomer decreases in intensity until the equilibrium ratio, approx. 8:1, of the two isomers is reached. the rate of the heme disorder kinetics was investigated for cytochrome b5 as a function of ph, oxidation state and 2,4 ...	1986	3790573
1h-nmr assignments and the dynamics of interconversion of the isomeric forms of cytochrome b5 in solution.	cytochrome b5 reconstituted with specifically deuterated hemins has led to the assignment of the resolved 6,7 beta-propionate protons and heme meso protons. freshly reconstituted cytochrome b5 contains a mixture of two isomers in an approx. 1:1 ratio. as time proceeds the minor isomer decreases in intensity until the equilibrium ratio, approx. 8:1, of the two isomers is reached. the rate of the heme disorder kinetics was investigated for cytochrome b5 as a function of ph, oxidation state and 2,4 ...	1986	3790573
estimation of regional gas and tissue volumes of the lung in supine man using computed tomography.	this study was intended to discover how well computed tomography could recover the volume and weight of lung like foams in a body like shell, and then how well it could recover the volume and weight of the lungs in supine man. model thoraces were made with various loaves of bread submerged in water. computed tomography scans recovered the volume of the model lungs (true volume range 250-12,500 ml) within +0.2 (sd 68) ml and their weights (true range 72-3125 g) within +30 (78) g. scans also recov ...	1986	3787544
successful oocyte retrieval and in vitro fertilization following ultrasound-directed aspiration of endometriomas.		2013	3783016
changes in regional myocardial perfusion by muscarinic receptor subtypes in dogs.	to determine the muscarinic receptor subtype (m1 or m2 or both) responsible for cholinergic coronary vasodilatation and alterations in the transmural distribution (endocardial to epicardial blood flow ratio) of coronary blood flow, systemic and coronary haemodynamic indices and regional myocardial blood flow (radioactive microspheres) were measured in anaesthetised dogs. submaximal vasodilative doses of the mixed muscarinic agonist acetylcholine were given by intracoronary infusion to avoid peri ...	1986	3779744
myoelectric correlates of colonic motor complexes and contractile activity.		1986	3777176
endosulfan induced inhibition of 3h-5-hydroxytryptamine uptake in platelets.	endosulfan, a chlorinated pesticide, is widely used to control various insect pests. rats exposed to 1 mg and 3 mg endosulfan/kg for periods of 10, 30, and 60 days showed significant (p less than 0.05) inhibition of [3h]5-hydroxytryptamine (5-ht) uptake by platelet-rich plasma (prp) in an ex vivo study. rats treated with endosulfan (1 and 3 mg/kg) up to 60 days elucidated a marked inhibition of adp-induced aggregatory responses of the platelets. incubation of prp with 10 microm and 100 microm en ...	1986	3775804
in vivo stability of in vitro labelled 99tcm-red blood cells for radionuclide determination of left ventricular ejection fractions and volumes.	serial determination of radionuclide left ventricular ejection fraction and volumes require a label that remains highly stable after introduction into the human circulation. we have evaluated the in vivo stability of 99tcm-red blood cells (99tcm-rbc) labelled in vitro by preparation with small amounts of a stannous agent in 19 patients with coronary artery disease. the distribution volume of 99tcm-rbc was virtually identical to that of rbc labelled with 51cr. labelling efficiency expressed as th ...	1986	3774253
bacteriological methods in diagnosis of tuberculous meningitis.		2007	3771495
midazolam in the intensive care unit.		2010	3769775
[establishment of a spontaneously transformed human fetal lung cell line and its biological characteristics].	a spontaneously transformed human fetal lung cell line (hflt) was derived from a human fetal lung diploid fibroblast cell line (2bs) by continuous culture. the biological characteristics of this cell line were studied and compared with those of 2bs cells. accompanying the morphological alteration, the growth rate of the transformed cell was accelerated and the maximum cell density was increased. the anchorage-independent growth was shown by its ability to form colonies in soft agar. the collagen ...	1986	3769747
[diagnosis and treatment of neuroblastoma in children--analysis of 98 patients].	from 1959 to 1982, 98 patients with neuroblastoma were treated in our hospital. seventy-eight were diagnosed by pathology and 69 (88.5%) were followed for 1 approximately 18 years. 50(51%) had already had distant metastasis (22, to bone) on admission. operation was performed on 53 patients (total excision on 18, partial excision on 11 and biopsy on 24 patients). the 1 and 15 year survival rates were 31.4% and 12.9%. the survival curve levelled off from the second year of the operation and remain ...	2009	3769741
effects of subchronic pyridostigmine pretreatment on the toxicity of soman.	the effect of subchronic pyridostigmine pretreatment on the toxicity of soman, in the absence of supporting therapy (atropine, oxime, and (or) anticonvulsant), as well as its effect on muscarinic cholinoceptor binding characteristics was assessed in the rat. pretreatment with pyridostigmine by means of an implanted alzet osmotic minipump for a 5-day total exposure dose of 12 mg/kg inhibited whole blood acetylcholinesterase activity by 73%. this pyridostigmine pretreatment lowered the soman ld50 ...	1986	3768795
antiprotease capacity in acute pancreatitis.	serial measurements of circulating antiproteases were carried out on 42 consecutive patients admitted with acute pancreatitis. in the 7 days following admission the serum levels of alpha 1 antitrypsin (alpha 1 at), alpha 1 antichymotrypsin (alpha 1 act) and the trypsin inhibitory capacity (tic) increased by more than 300 per cent. the serum concentration of alpha 2 macroglobulin (alpha 2 m) alone showed a decline which was most profound in those patients with severe acute pancreatitis. initial e ...	2010	3768647