Publications

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[isolation of a ph stabile variant of foot and mouth disease virus and its multiplication in tissue cultures with acid medium]. 195913669673
[a method for rapid adaptation of foot and mouth disease virus to frenkel tissue culture]. 195913669661
[behavior of foot and mouth disease virus for adsorption in aluminum hydroxide and subsequent elution. iii. purification and concentration of foot and mouth disease virus through aluminum hydroxide]. 195913669657
[behavior of foot and mouth disease virus during adsorption in aluminum hydroxide and subsequent elution. ii. effect of foreign protein on the adsorption and elution process]. 195913669643
[behavior of foot and mouth disease virus during adsorption in aluminum hydroxide and subsequent elution. i. study of the factors which influence adsorption and elution]. 195913669642
studies with infective ribonucleic acid from tissues and cell cultures infected with the virus of foot-and-mouth disease. 195913669312
densitygradient centrifugation with infectious ribonucleic acid of foot-and-mouth disease virus.the sedimentation constant of an infectious component in ribonucleic acid preparations from foot-and-mouth disease virus has been determined by density-gradient centrifugation. a sedimentation constant of 37 svedberg units (s(t)) was obtained. on the assumption that the relation between the molecular weight and the sedimentation constant found by gierer is applicable to our system as well, a value of 3.1 x 10(6) was calculated for the molecular weight of the infectious component.195913668550
[determination of the sedimentation constant of the infectious principle with nucleic acid character of foot and mouth disease virus with the aid of gradient centrifugation]. 195913660170
[multiplication and cytopathogenic effect of foot and mouth disease in calf renal epithelium tissue cultures]. 195913659975
[pathogenesis of myocarditis caused by foot and mouth disease virus (experimental studies on the adult mouse)]. 195913659832
[remarks on the type c strain of foot-and-mouth disease virus in mice and young rabbits (3 to 4 months old)]. 195913650293
[studies on aggregate formation and inactivation of the virus of foot and mouth disease]. 195913648631
[significance of ulcerative lesions of the lingual mucosa in the assay of aphthous virus on vaccinated cattle]. 195913639383
some applications of detergents to the study of the virus of foot-and-mouth disease. 195913631183
[the infectious ribonucleic acid of foot-and-mouth disease virus]. 195913629915
[foot and mouth disease virus in tissue culture in vitro. vi. preparation and titration of anti-foot and mouth disease serum obtained from cattle]. 195813624145
effect of temperature on the multiplication of foot-and-mouth disease virus in suspensions of kidney cells of the pig. 195813622662
[studies on aphthous virus (type c) in monocellular layer of swine kidney by plaque method]. 195813606509
[foot and mouth disease virus in tissue cultures in vitro. v. inhibition between active foot and mouth disease viruses of type o and type a4]. 195813602180
[foot and mouth disease virus in tissue cultures in vitro. iv. interference test between virus (a4) inactivated by heat or by formaldehyde and homologous active virus]. 195813602179
[foot and mouth disease virus in tissue cultures in vitro. iii. neutralization with immune sera in vitro and complement deviating activity of a4, o, and c viruses at different stages of development]. 195813602178
[plaque formation by foot & mouth disease virus]. 195813595666
adaptation of the type c cattle virus of foot-and mouth disease to the brain of the white mouse. 195813594720
use of two properties of the virus of foot-and-mouth disease in studies of its multiplication. 195813590081
[cytopathogenic effect of foot and mouth disease virus in monolayer cultures of swine kidney tissue]. 195813583661
serological studies with the virus of vesicular stomatitis. i. typing of vesicular stomatitis viruses by complement fixation. 195813583398
infectivity of ribonucleic acid from mice and tissue culture infected with the virus of foot-and-mouth disease. 195813577908
[modifications of the virulence of a strain of aphthous virus by successive passage in rabbits]. 195813561646
[characteristics of local anti-aphthous immunity as demonstrated by the titer of foot-and mouth disease virus in vaccinated cattle]. 195813547474
biological factors influencing the effectiveness of wood preservatives against decay. 195813534308
[immuno-electrophoresis applied to foot and mouth disease virus]. 195813534073
[culture of aphthous fever virus (type o) in tissue culture of pig kidneys. ii. study with electron microscope of the development of the infected cells]. 195813534054
the inactivation of foot-and-mouth disease virus by formalin. 195713521955
application of agar gel precipitin tests to the study of the virus of foot-and-mouth disease. 195813519754
purification and electron microscopy of foot-and-mouth disease virus. 195813518367
a special reaction of the complement fixation test applied to the study of tumours. 195813517240
the virus of foot-and-mouth disease. 195813508401
experiments on the activating and protective effects of some organic substances on foot-and-mouth disease virus. 195813508247
experimental mixed infection of cattle with foot-and-mouth disease viruses. 195813498240
a plaque assay for foot-and-mouth disease virus and kinetics of virus reproduction. 195713496542
[trial preservation of type o aphthous fever virus of a guinea pig-adapted strain on the leech (hirudo medicinalis), an unusual host for this virus]. 195713473235
[culture of foot and mouth disease virus (type o) in swine kidney tissues. i. study of infectivity]. 195713470421
physico-chemical and immunological studies on the virus of foot-and-mouth disease and its host tissue microsomes. 195713469414
[the aphthous virus in tissue culture in vitro. ii. growth curve of a4, o and c strains, in vitro and in vivo]. 195713466184
[the aphthous virus in tissue culture in vitro. i. cultivation of a4, o and c strains trypsinized swine kidney cells]. 195713466183
multiplication of foot and mouth disease virus in adult kidney, and embryonic lung and heart bovine tissue cultures. 195713465773
[adaptation of the aphthous virus in newborn rabbits]. 195713447284
multiplication of the virus of foot-and-mouth disease in culture. 195713439158
inactivation of foot-and-mouth disease virus by ph and temperature changes and by formaldehyde. 195713432017
experimental examination of complexes with foot-and-mouth disease virus. 195713424287
specific precipitin reactions with the viruses of foot-and-mouth disease and vesicular stomatitis. 195713407713
[not available]. 195613383845
research on foot-and-mouth disease. x. the titration of cultivated food-and-mouth disease virus (frenkel) in cattle compared with the titer obtained in the quantitative complement-fixation test. 195613340107
[research on multiplication of aphthous virus in tissue cultures. ii. biochemical study of long-term cultures]. 195513323669
[research on multiplication of aphthous virus in tissue cultures. i. biological study of long-term cultures]. 195513323668
[preservation of viruses in unusual hosts: amphibia and hirudinea]. 195513318435
[new method of production of the aphthous fever virus in large quantities in the cow and properties of the virus obtained in such a way]. 195613305043
[type determination of foot and mouth disease viruses by agar-gel diffusion]. 195513286876
cultivation of the foot-and-mouth disease virus in explanted epithelium of the bovine tongue. ix. growth characteristics of the virus in large scale tissue cultures. 195613283228
[typing of foot and mouth disease virus]. 195513276525
foot-and-mouth disease virus: its growth and cytopathogenicity in tissue culture. 195513274090
growth and titration of the viruses of foot-and mouth disease and vesicular stomatitis in kidney monolayer tissue cultures. 195513265768
electrophoretic properties of foot and mouth disease virus. 195513259503
research on foot-and-mouth disease. viii. titration of foot-and-mouth disease virus making use of surviving tongue epithelium from vaccinated cattle. 195513259024
control of yeast contamination by mycostatin in cultures of the virus of foot-and-mouth disease. 195513253607
differentiation between foot-and-mouth disease and vesicular stomatitis viruses by means of mouse inoculation. 195513238756
the sterilizing action of gaseous ethylene oxide on foot-and-mouth disease virus; a preliminary report. 195513228886
[adsorbing power of protein complexes with regard to the foot-and-mouth disease virus and possibility of liberating the latter by ultrafiltration]. 195413209896
[separation by ultrafiltration of foot-and-mouth disease virus from molecules larger than the virus and from molecules smaller than the virus]. 195413209889
on the stability of bovine foot-and-mouth disease virus dependent on ph; investigations on the complement fixing and the immunizing antigen as well as on the infective agent. 195413206774
electrophoresis of the virus of foot-and-mouth disease. iii. mobility studies on the greater complement fixing particle and its splitting by ph-6.5. 195413206773
[change of type of the foot and mouth diseases virus]. 195413206702
electrophoresis of the virus of foot-and-mouth disease. ii. mobility of the lesser complement fixing particle. 195413197050
electrophoresis of the virus of foot-and-mouth disease. i. mobility experiments suggesting a close relation between virus and host microsomes. 195413197049
[behavior of three types of aphthous virus during electrophoresis in starch]. 195413195290
susceptibility and serological response of various species of animals to infection with the virus of vesicular stomatitis. 195413171515
research on foot-and-mouth disease. vii. cultivation of the virus on a practical scale in explantations of tongue epithelium; a modification of the culture technique. 195413171490
[repeated passages of foot and mouth virus c from guinea pig foot to mouse perineum do not permit the adaptation of a viscerotropic strain to the mouse]. 195413161366
[adaptation of the foot and mouth disease virus to merion]. 195413161349
ultracentrifugation of the virus of foot-and-mouth disease. iv. splitting of the greater complement-fixing particle. 195413158029
ultracentrifugation of the virus of foot-and-mouth disease. iii. verification of the existence of two particles of different size carrying the complement-fixing antigen. 195413158028
titration of the virus of foot-and-mouth disease in culture. 195413152368
electrophoretic studies of foot-and-mouth disease virus. 195413148477
[the culture of foot and mouth disease virus on an industrial scale]. 195313135049
influence of cortisone on susceptibility of adult mice to foot-and-mouth-disease virus. 195413124695
[establishment of a relation between the variations of the properties of foot and mouth disease virus cultured on elective embryoma, and the stages of clinical evolution of the foot and mouth disease; individualization of the optimum stage for the preparation of vaccines]. 195313107168
a preliminary report on the purification of foot-and-mouth disease virus by serological methods. 195313084913
[foot and mouth disease virus in newborn laboratory animals]. 195213064820
[the aphtha virus cultured in vivo on a specific and elective embryoma, and anti-aphthous vaccination]. 195313051893
transmission of fmd by people. 200312974344
monitoring of fmd virus non-structural protein 3ab antibody in intensive pig farms after a severe outbreak of fmd. 200312974342
additional thoughts on the funding of poliovirus research: some reflections stimulated by "parallel path: poliovirus research in the vaccine era" (m.s. garfinkel and d. sarewitz). 200312971294
molecular weapons against agricultural vulnerability and the war on terror.the multiple reports in this issue of the journal from the agenda for action conference, coupled with the analysis by the national academy of sciences, the national research council, and the auditor general (uk) on bioterror preparedness and homeland security, highlight the immediate need for rapid disease detection and advanced diagnostic capabilities to protect the public health, animal agriculture, and the numerous associated economies in the united states. in response to the potentially deva ...200312970863
resistance of virus to extinction on bottleneck passages: study of a decaying and fluctuating pattern of fitness loss.rna viruses display high mutation rates and their populations replicate as dynamic and complex mutant distributions, termed viral quasispecies. repeated genetic bottlenecks, which experimentally are carried out through serial plaque-to-plaque transfers of the virus, lead to fitness decrease (measured here as diminished capacity to produce infectious progeny). here we report an analysis of fitness evolution of several low fitness foot-and-mouth disease virus clones subjected to 50 plaque-to-plaqu ...200312960384
synthetic peptides. 200312958453
procedures for preventing the transmission of foot-and-mouth disease virus to pigs and sheep by personnel in contact with infected pigs.the most effective method of containing an outbreak of foot-and-mouth disease (fmd) is by the culling of livestock. however, qualified people must diagnose the disease before the culling can begin, and they must avoid susceptible animals after having been in contact with infected premises, to prevent them from transmitting the virus. to test the effectiveness of biosecurity procedures in preventing the transmission of fmd virus (o/uk/35/2001) investigators contacted and sampled pigs inoculated w ...200312934795
rna-dependent rna polymerase gene sequence from foot-and-mouth disease virus in hong kong.a foot-and-mouth disease virus (fmdv, hkn/2002) was isolated in hong kong in 2002. the nucleotide sequence of the 3d(pol) gene encoding the viral rna-dependent rna polymerase was determined and compared with that of the same gene from other fmdvs. the 3d(pol) gene was 1410 nucleotides in length encoding a protein of 470 amino acid residues. sequence comparisons indicated that hkn/2002 belonged to serotype o. an evolutionary tree based on the 3d(pol) sequences of 20 fmdv isolates revealed that th ...200312927804
biological effect of varying peptide binding affinity to the bola-drb3*2703 allele.mhc class i and ii molecules are immunoregulatory cell surface glycoproteins, which selectively bind to and present antigenic peptides to t-lymphocytes. murine and human studies show that variable peptide binding affinity to mhc ii molecules influences th1/th2 responses by inducing distinctive cytokine expression. to examine the biological effects of peptide binding affinity to bovine mhc (bola), various self peptides (bola-dq and fibrinogen fragments) and non-self peptides from ovalbumin (ova), ...200312927080
a synthetic peptide containing the consensus sequence of the g-h loop region of foot-and-mouth disease virus type-o vp1 and a promiscuous t-helper epitope induces peptide-specific antibodies but fails to protect cattle against viral challenge.a pilot study was carried out in cattle to determine the immunogenicity of a synthetic consensus peptide comprising the g-h loop region of foot-and-mouth disease virus (fmdv) type-o vp1 and a non-vp1 t-helper (th) epitope. cattle vaccinated intramuscularly either once (n = 5) or twice (n = 4) with 50 microg of the peptide preparation at a 21-day interval developed antibodies to the peptide as determined by elisa with the exception of one steer that received a single dose. however, neutralizing a ...200312922108
induction of immunity in swine by purified recombinant vp1 of foot-and-mouth disease virus.vp1, a capsid protein of foot-and-mouth disease virus (fmdv), contains neutralizing epitopes of the virus. due to its poor water solubility, recombinant escherichia coli derived vp1 (rvp1) has previously been used mainly in a denatured form and is not well characterized. here, using sds to assist protein refolding and then removing sds with a detergent removing column, we have successfully purified rvp1 in two aqueous-soluble forms, i.e. monomer and dimer. studies showed that dimerization occurs ...200312922103
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