Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
|---|
| long beneficial effects after lipo-prostaglandin e1 administration on the ischemic gastric tube in pigs. | lipo-prostaglandin e1 (pge1) is a new preparation of pge1 in which it is bound to lipids in order to slow pge1 release and delay its rate of metabolism. we investigated how long the beneficial effects of intravenous administration of lipo-pge1 on the ischemic gastric tube continue. the gastric tube was constructed using 15 domestic pigs under general anesthesia and saline, unmodified pge1 and lipo-pge1 were infused continuously at a rate of 0.05 microg/kg/min for 10 minutes. tissue blood flow (t ... | 2008 | 18564164 |
| pharmacokinetics of artesunate in the domestic pig. | the aim was to study the pharmacokinetic profile of artesunate and its metabolite dihydroartemisinin (dha) in a pig model. | 2008 | 18559353 |
| [an investigation of the protective effect of prostaglandin e1 liposome on acute lung injury in pig]. | to assess the protective effect of prostaglandin e1 liposome (lipo-pge1) on acute lung injury (ali) in a porcine model of ali. | 2008 | 18549714 |
| nutritional skewing of conceptus sex in sheep: effects of a maternal diet enriched in rumen-protected polyunsaturated fatty acids (pufa). | evolutionary theory suggests that in polygynous mammalian species females in better body condition should produce more sons than daughters. few controlled studies have however tested this hypothesis and controversy exists as to whether body condition score or maternal diet is in fact the determining factor of offspring sex. here, we examined whether maternal diet, specifically increased n-6 polyunsaturated fatty acid (pufa) intake, of ewes with a constant body condition score around the time of ... | 2008 | 18541015 |
| sex-related variation in compact bone microstructure of the femoral diaphysis in juvenile rabbits. | while gross morphological changes in the skeleton between males and females are well know, differences between sexes in the histomorphology are less known. it is important to have knowledge on the bone structure of rabbits, as this is a widely used species in biomedical research. a study was performed to evaluate the association between sex and the compact bone morphology of the femoral diaphysis in juvenile rabbits. | 2008 | 18522730 |
| [therapeutic effect of vacuum-assisted closure technology on infected explosion wound of pig]. | to investigate the effect of vacuum-assisted closure (v. a. c.) technology in the treatment of infected wound of skin and soft tissue as a result of explosion injury in pig. | 2008 | 18512552 |
| non-robotic thoracoscopic internal mammary artery preparation in the pig. a training model. | notwithstanding non-robotic, thoracoscopic preparation of the internal mammary artery (ima) is a difficult surgical task, an appropriate experimental training model is lacking. we evaluated the young domestic pig for this purpose. four domestic female pigs (30-40 kg body weight) were used for this study. bilateral thoracoscopic preparation of the ima was carried out under continuous, pressure controlled co(2) insufflation. a 30 degrees rigid thoracoscope was inserted through a 10-mm port in the ... | 2008 | 18502784 |
| greenlight (532 nm) laser partial nephrectomy followed by suturing of collecting system without renal hilar clamping in porcine model. | to assess the feasibility of partial nephrectomy (pn) without renal hilar clamping using the 80-w greenlight (532 nm) laser with opening of the collecting system followed by its suture in a porcine model. | 2009 | 18502479 |
| isolation and characterisation of rhodococcus equi from submaxillary lymph nodes of wild boars (sus scrofa). | rhodococcus equi has been isolated from the submaxillary lymph nodes of domesticated pigs, but little is known about the presence of r. equi in wild boars. the aim of the study was the evaluation of the incidence of r. equi in wild boars and the characterisation of them. of 482 submaxillary lymph nodes of wild boars shot in 39 settlements throughout hungary, r. equi was isolated from 60 specimens, and plasmid types of 82 isolates were examined. the isolates were tested for the presence of 15-17- ... | 2008 | 18499361 |
| diagnostic specificity of a real-time rt-pcr in cattle for foot-and-mouth disease and swine for foot-and-mouth disease and classical swine fever based on non-invasive specimen collection. | foot-and-mouth disease virus (fmdv) and classical swine fever virus (csfv) are highly contagious and can cause great economic losses when introduced into disease-free regions. accurate estimates of diagnostic specificity (sp) are important when considering the implementation of surveillance for these agents. the purpose of this study was to estimate diagnostic sp of a real-time reverse-transcriptase pcr assay developed for detection of fmdv in cattle and domestic swine and csfv in domestic swine ... | 2008 | 18499360 |
| attenuating the defibrillation dosage decreases postresuscitation myocardial dysfunction in a swine model of pediatric ventricular fibrillation. | the optimal biphasic defibrillation dose for children is unknown. postresuscitation myocardial dysfunction is common and may be worsened by higher defibrillation doses. adult-dose automated external defibrillators are commonly available; pediatric doses can be delivered by attenuating the adult defibrillation dose through a pediatric pads/cable system. the objective was to investigate whether unattenuated (adult) dose biphasic defibrillation results in greater postresuscitation myocardial dysfun ... | 2008 | 18496405 |
| prevalence of cryptosporidium genotypes in pre and post-weaned pigs in australia. | a total of 289 pig faecal samples were collected from pre-weaned and post-weaned piglets and sows from 1 indoor and 3 outdoor piggeries located in the south-west region of western australia and screened at the 18s rrna locus for the presence of cryptosporidium. an overall prevalence of 22.1% (64/289) was identified. cryptosporidium was more prevalent in post-weaned animals (p<0.05); 32.7% (51/156) versus 10.6% (13/123) for pre-weaned animals. sequence analysis identified cryptosporidium suis in ... | 2008 | 18486131 |
| risk factors associated with renal parenchymal fracture during laparoscopic cryoablation. | to assess the risk factors for haemorrhage and renal fracture associated with renal cryoablation. | 2008 | 18485040 |
| immediate post-shock chest compressions improve outcome from prolonged ventricular fibrillation. | this study was designed to test the hypothesis that immediate post-shock chest compressions improve outcome from prolonged ventricular fibrillation (vf) compared with typical "hands off" period (i.e., delayed post-shock compressions) associated with aed use. | 2008 | 18482786 |
| attainment of local drug delivery with paclitaxel-eluting balloon in porcine coronary arteries. | our purpose was to confirm the local drug delivery of a paclitaxel-eluting balloon by percutaneous intervention of single arterial segments or bifurcations of porcine coronary arteries. | 2008 | 18480668 |
| transumbilical endoscopic cholecystectomy with the trichannel trocar technique: a porcine feasibility study. | the aim of this study is to verify the feasibility of another option: transumbilical endoscopic cholecystectomy by using the trichannel trocar technique. eight domestic pigs were submitted to transumbilical endoscopic cholecystectomy by using the trichannel trocar technique. a fine grasper of 2 mm in diameter was inserted through a small skin incision on the right upper abdomen for grasping the gallbladders. the natural scar of the umbilicus was restored after extract of the specimen. all the ga ... | 2008 | 18480087 |
| foreign-body granulomas within intramyocardial arteries in a transcoronary safety assessment in pigs. | foreign-body granulomas within intramyocardial arteries were detected in three domestic pigs (sus scrofa domestica) in a routine transcoronary safety assessment study. the foreign bodies stained light grayish-blue by hematoxylin and eosin (h&e) and were strongly birefringent by polarized light microscopy. by their morphological features, they were identified as cotton fibers. embolization of foreign-body material into the myocardial arteries following catheter-based procedures is an unusual even ... | 2008 | 18467686 |
| low levels of haptoglobin and putative amino acid sequence in taiwanese lanyu miniature pigs. | porcine haptoglobin (hp) is an acute phase protein. its plasma level increases significantly during inflammation and infection. one of the main functions of hp is to bind free hemoglobin (hb) and inhibit its oxidative activity. in the present report, we studied the hp phenotype of taiwanese lanyu miniature pigs (tly minipigs; n=43) and found their hp structure to be a homodimer (beta-alpha-alpha-beta) similar to human hp 1-1. interestingly, western blot and high performance liquid chromatographi ... | 2008 | 18460833 |
| robotic notes (natural orifice translumenal endoscopic surgery) in reconstructive urology: initial laboratory experience. | to present an initial experience with robotic natural orifice translumenal surgery (r-notes) in reconstructive urology using the da vinci surgical system. | 2008 | 18455769 |
| influence of methylmalonyl-coa mutase alleles on resistance to bovine tuberculosis in the european wild boar (sus scrofa). | an association study was carried out to examine the influence of methylmalonyl-coa mutase (mut) polymorphisms on the susceptibility of a well-studied wild boar population from southern spain to develop bovine tuberculosis (btb). to this end, we examined polymorphisms at a closely linked dinucleotide microsatellite flanking exon 2 of the mut gene in 37 wild boars with btb and 36 non-infected individuals. the microsatellite showed low polymorphism in the studied population, with only three alleles ... | 2008 | 18454807 |
| portal vein segmentation of a 3d-planning system for liver surgery--in vivo evaluation in a porcine model. | computer systems allow the planning of complex liver operations. the segmentation of intrahepatic vessels builds the basis for the calculation of liver segments and resection proposals. for surgical use, it is essential to know the capabilities and limitations of the segmentation. the aim of this study was to determine the sensitivity and precision of the portal vein segmentation of a computer planning system for liver surgery in vivo. | 2008 | 18449610 |
| imaging of the coronary venous system: validation of three-dimensional rotational venous angiography against dual-source computed tomography. | information on the anatomy of the cardiac venous system (cvs) is increasingly important for cardiac resynchronization therapy or percutaneous transvenous mitral valve annuloplasty. three-dimensional (3d) imaging can further improve the understanding of the relationship of cardiac structures. this study was performed to validate the accuracy of rotational coronary sinus angiography (csa) displaying the 3d anatomy of the cvs compared to ecg-gated, contrast-enhanced, cardiac dual-source computed to ... | 2008 | 18449597 |
| transcription analysis in the melim swine model identifies rack1 as a potential marker of malignancy for human melanocytic proliferation. | metastatic melanoma is a severe disease. few experimental animal models of metastatic melanoma exist. melim minipigs exhibit spontaneous melanoma. cutaneous and metastatic lesions are histologically similar to human's. however, most of them eventually spontaneously regress. our purpose was to investigate whether the melim model could reveal markers of malignancy in human melanocytic proliferations. | 2008 | 18442364 |
| epidemiological survey of swine influenza a virus in selected wild boar populations in germany. | the aim of this study was to evaluate the epidemiological situation of swine influenza virus (siv) infections in different wild boar populations in germany based on a serological surveillance in some bundeslaender (federal states) in connection with virological investigations in wild boar shot in northern germany (mecklenburg-western pomerania, district of nordvorpommern). altogether, 1245 sera from wild boar were tested using the hemagglutination inhibition test. the established seroprevalence ... | 2008 | 18440732 |
| gene silencing of cd47 and antibody ligation of thrombospondin-1 enhance ischemic tissue survival in a porcine model: implications for human disease. | insufficient tissue perfusion underlies many acute and chronic diseases. tissue perfusion in turn requires adequate blood flow, determined in large part by the relative state of relaxation or constriction of arterial vessels. nitric oxide (no) produced by vascular cells modulates blood flow and tissue perfusion by relaxing and dilating arteries. recently, we reported that the secreted protein thrombospondin-1 (tsp1), through its cell surface receptor cd47, limits the ability of no to relax and d ... | 2008 | 18438125 |
| hybrid natural orifice translumenal surgery (notes) sleeve gastrectomy: a feasibility study using an animal model. | the indications for natural orifice translumenal surgery (notes) are yet to be determined. morbidly obese patients may be one population that would benefit from this approach due to the elimination of wound complications and possibly a faster recovery. as a bariatric restrictive procedure, sleeve gastrectomy could be one indication for notes. to test the feasibility of this procedure with a notes approach, a pig model was used. | 2008 | 18437477 |
| influenza exposure in united states feral swine populations. | swine play an important role in the disease ecology of influenza. having cellular receptors in common with birds and humans, swine provide opportunities for mixed infections and potential for genetic reassortment between avian, human, and porcine influenza. feral swine populations are rapidly expanding in both numbers and range and are increasingly coming into contact with waterfowl, humans, and agricultural operations. in this study, over 875 feral swine were sampled from six states across the ... | 2008 | 18436668 |
| prearrest administration of low-molecular-weight heparin in porcine cardiac arrest: hemodynamic effects and resuscitability. | both animal and human studies demonstrate activation of coagulation during cardiac arrest. prearrest anticoagulation is used routinely in many experimental studies. we studied the hemodynamic effects of prearrest anticoagulation with a low-molecular-weight heparin suitable for clinical use during cardiopulmonary resuscitation in pigs. | 2008 | 18431276 |
| neurocognitive performance after cardiopulmonary resuscitation in pigs. | to test the feasibility of a neurocognitive test based on operant conditioning in a porcine model of cardiac arrest and cardiopulmonary resuscitation. furthermore, to characterize the influence of different durations of cardiac arrest on cognitive performance and the accompanying neurohistopathological changes. | 2008 | 18431271 |
| bone regeneration after topical bmp-2-gene delivery in circumferential peri-implant bone defects. | the aims of this study were to evaluate the rate of bone formation and osseointegration after topical gene delivery with a liposomal vector system carrying bone morphogenetic protein (bmp)-2 cdna in combination with a collagen carrier and autologous bone as a carrier in freshly created peri-implant bone defects. | 2008 | 18422983 |
| conventional high pressure versus newly developed continuous-flow ureterorenoscope: urodynamic pressure evaluation of the renal pelvis and flow capacity. | we evaluated the pressure and flow relation of a newly developed continuous-flow ureterorenoscope (urs) in comparison with a common ureterorenoscope in an ex-vivo urinary tract model. | 2008 | 18419336 |
| plasmin-matrix metalloproteinase cascades in spinal response to an experimental disc lesion in pig. | proteinases were immunohistochemically stained to analyze degenerated discs and paradiscal tissues in comparison to contiguous control tissues in an experimental porcine model of intervertebral disc degeneration. | 2008 | 18404101 |
| chitosan hemostatic dressing for renal parenchymal wound sealing in a porcine model: implications for laparoscopic partial nephrectomy technique. | this study was to evaluate the feasibility of using a novel chitosan hemostatic dressing to control hemorrhage and urinary leakage by sealing off the parenchymal wound following lpn. | 2008 | 18402734 |
| detection and analysis of porcine circovirus type 1 in hungarian wild boars: short communication. | porcine circovirus type 1 (pcv1) is considered to be a non-pathogenic virus detected in cell cultures, vaccines or products used for cell culture preparations, all of them of porcine origin. serological evidence and genetic studies suggested that pcv1 was widespread in domestic pigs. the presence of pcv1 in wild boars in germany was also described using serological methods. this paper reports the first detection of pcv1 in hungarian wild boars. samples were collected at slaughterhouses and proce ... | 2008 | 18401965 |
| development of the movement of the epiglottis in infant and juvenile pigs. | although backward folding of the epiglottis is one of the signal events of the mammalian adult swallow, the epiglottis does not fold during the infant swallow. how this functional change occurs is unknown, but we hypothesize that a change in swallow mechanism occurs with maturation, prior to weaning. using videofluoroscopy, we found three characteristic patterns of swallowing movement at different ages in the pig: an infant swallow, a transitional swallow and a post-weaning (juvenile or adult) s ... | 2008 | 18387794 |
| cytokine mrna expression and pathological findings in pigs inoculated with african swine fever virus (e-70) deleted on a238l. | african swine fever virus (asfv) induces a variety of immune responses and clinical forms in domestic pigs. as it is the only member of the asfarviridae family, asfv encodes many novel genes not encoded by other virus families. among these genes, a238l may regulate the synthesis of pro-inflammatory cytokines, controlled mainly by nfkappab and nfat pathways. in this study, we inoculated two groups of pigs, one with the asfv highly virulent e-70 isolate, deleted on a238l gene, and the other group ... | 2008 | 18384883 |
| expec-typical virulence-associated genes correlate with successful colonization by intestinal e. coli in a small piglet group. | upon studying the transmission of escherichia coli from a sow to five of her piglets, we observed domination of the coliform flora in piglets by a single e. coli clone, especially after weaning. this haemolytic cloneh1 did not harbour any virulence determinants typical for intestinal pathogenic e. coli isolates from swine but had a virulence gene profile very similar to extraintestinal e. coli (expec), including genes coding for p fimbriae and several iron acquisition systems, besides having an ... | 2008 | 18373678 |
| myocardial cytokine il-8 and nitric oxide synthase activity during and after resuscitation: preliminary observations in regards to post-resuscitation myocardial dysfunction. | increases in serum cytokines have been reported after successful resuscitation from prolonged ventricular fibrillation (vf). pro-inflammatory cytokines can stimulate inducible nitric oxide synthase (inos) to produce excessive levels of nitric oxide (no). high levels of both myocardial inflammatory cytokines and nitric oxide levels can depress myocardial contractile function. we hypothesized that myocardial pro-inflammatory cytokines and inos activity would increase following successful resuscita ... | 2008 | 18359140 |
| comparison of a novel radially dilating balloon ureteral access sheath to a conventional sheath in the porcine model. | traditional ureteral access sheaths rely on tapered dilators and the dotter principle of axial force to gain access into the ureter. we compared the performance of a novel balloon expandable ureteral access sheath using radial dilatation with that of a conventional ureteral access sheath. | 2008 | 18355865 |
| rapid communication: robot-assisted notes nephrectomy: initial report. | natural orifice transluminal endoscopic surgery (notes) using the davinci robot (intuitive surgical, sunnyvale, ca) has never been applied to urologic surgery. here we present our initial experience with a combined transvaginal and transcolonic, single-port, robot-assisted notes nephrectomy. | 2008 | 18355143 |
| production of viable cloned miniature pig embryos using oocytes derived from domestic pig ovaries. | for production of viable somatic cell nuclear transferred (scnt) miniature pig embryos, in vitro condition for controlling the quality of recipient oocytes derived from domestic pig ovaries should be evaluated. in the present study, to get information on optimal in vitro maturation (ivm) condition of oocytes, we investigated the effect of ivm duration of recipient oocytes on subsequent development of scnt miniature pig embryos, the maturation-promoting factor (mpf) activity in recipient oocytes ... | 2008 | 18352818 |
| similarity of the swine vasculature to the human carotid bifurcation: analysis of arterial diameters. | we assessed the similarities of the iliac bifurcation in two breeds of swine to the known human carotid bifurcation, in order to assess its applicability as a preclinical model of the human carotid bifurcation. | 2008 | 18341957 |
| simulating the spread of classical swine fever virus between a hypothetical wild-boar population and domestic pig herds in denmark. | denmark has no free-range wild-boar population. however, danish wildlife organizations have suggested that wild boar should be reintroduced into the wild to broaden national biodiversity. danish pig farmers fear that this would lead to a higher risk of introduction of classical swine fever virus (csfv), which could have enormous consequences in terms of loss of pork exports. we conducted a risk assessment to address the additional risk of introducing and spreading csfv due to the reintroduction ... | 2008 | 18339438 |
| thermal effects of laparoscopic saline-enhanced radiofrequency cautery on renal parenchyma in a porcine model. | advances in the field of surgery have recently developed a number of devices and materials to improve surgical hemostasis. the effects of one such device, saline-cooled monopolar radiofrequency electrocautery, has been well scrutinized in splenic and hepatic applications. despite the utilization of this device in urologic surgery, the classification of the thermal effects has been poorly characterized to date. the purpose of this study was to discern the thermal characteristics of the device in ... | 2008 | 18315485 |
| potential for cavitation-mediated tissue damage in shockwave lithotripsy. | shockwave lithotripsy (swl) injures renal tissue, and cavitation has been reported to mediate some of these effects. much of the work characterizing the cavitation injury of swl has been performed in small animals or in vitro. we describe experiments that promote cavitation during swl and estimate the spatial distribution of the resulting hemorrhagic lesion in a large-animal (porcine) model of clinical lithotripsy. | 2008 | 18315482 |
| bioavailability of heme iron in biscuit filling using piglets as an animal model for humans. | the objective of this work was to evaluate the bioavailability of heme iron added to biscuit filling. it comprised two stages: first, the development of the heme iron enriched biscuit filling; second, the evaluation of the bioavailability of the mineral in fattening piglets. two groups were selected randomly and fed: a) low iron feed and biscuits with heme iron supplemented filling; b) normal feed (with ferrous sulphate). weight and blood parameters were measured every fifteen days. averages wer ... | 2008 | 18311330 |
| discrimination of infant isolation calls by female greater spear-nosed bats, phyllostomus hastatus. | in colonial species, recognition of offspring should be under strong selection. for accurate identification to occur offspring must emit individually distinctive signals and parents must be able to discriminate between signals. female greater spear-nosed bats (phyllostomus hastatus) roost in stable social groups and use infant vocalizations, termed isolation calls, to locate and identify their young. in this study, we investigate both the production and perception of isolation calls in p. hastat ... | 0 | 18311319 |
| comparison of a novel one-step percutaneous nephrolithotomy sheath with a standard two-step device. | percutaneous nephrolithotomy (pcnl) is the treatment of choice for large renal calculi. the most widely used access sheath for pcnl involves two steps including placement of a high-pressure balloon catheter (hpbc) followed by advancement of a sheath over the balloon. a novel pcnl balloon/sheath combination (nss) has been developed that allows for both dilation and sheath placement in a single step. the objective of this study was to compare the safety and efficacy of the nss to the hpbc in a por ... | 2008 | 18308088 |
| porcine circovirus type 2 (pcv2) viral components immunomodulate recall antigen responses. | porcine circovirus type 2 (pcv2) is a single-stranded circular dna virus infecting domestic pigs worldwide. interaction of this virus with the immune system apparently modulates the immune response of the host. in the present study, the implication of different components of pcv2 in the modulation of the immune response of the host were investigated by using pcv2 viral-like particles (vlps) and 16 novel oligodeoxyribonucleotides containing cpg motifs (cpg-odns) based on the pcv2 genomic sequence ... | 2008 | 18304652 |
| hepatitis e virus: molecular virology, clinical features, diagnosis, transmission, epidemiology, and prevention. | hepatitis e virus (hev), the sole member of the genus hepevirus in the family of hepeviridae, is the major cause of several outbreaks of waterborne hepatitis in tropical and subtropical countries and of sporadic cases of viral hepatitis in endemic and industrialized countries. transmission of hev occurs predominantly by the fecal-oral route although parenteral and perinatal routes have been implicated. the overall death rate among young adults and pregnant women is 0.5-3% and 15-20%, respectivel ... | 2008 | 18297720 |
| production of transgenic and non-transgenic clones in miniature pigs by somatic cell nuclear transfer. | miniature pigs have been recognized as valuable experimental animals in various fields such as medical and pharmaceutical research. however, the amount of information on somatic cell cloning in miniature pigs, as well as genetically modified miniature pigs, is much less than that available for common domestic pigs. the objective of the present study was to establish an efficient technique of cloning miniature pigs by somatic cell nuclear transfer. a high pregnancy rate was achieved following tra ... | 2008 | 18296867 |
| indirect estimation of porcine parvovirus maternal immunity decay in free-living wild boar (sus scrofa) piglets by capture-recapture data. | linear mixed regression and logspline density estimation were performed to estimate the survival curve and half life of passively acquired antibodies against porcine parvovirus (ppv) in 44 wild boar piglets captured in the northern apennines, italy. one piglet had no detectable maternal antibodies at 2.5 months post partum and no antibodies were detected in any of the remaining piglets by 4 months of age. fitted survival curves indicated that maternal antibodies were undetectable from 2.5 to 6 m ... | 2009 | 18295517 |
| microwave ablation with triaxial antennas tuned for lung: results in an in vivo porcine model. | to prospectively determine in swine the size and shape of coagulation zones created in normal lung tissue by using small-diameter triaxial microwave antennas and to prospectively quantify the effects of bronchial occlusion and multiple antennas on the coagulation zone. | 2008 | 18292471 |
| tissue response to surgical energy devices. | there is little data available on the effects of energy-based surgical devices (esd) on tissues other than arteries and veins. as such, we quantified the lateral thermal damage associated with contemporary esd: the harmonic ace, a prototype bipolar device known as the gyrus trisector, the harmonic lcs-c5, and the ligasure v. | 2008 | 18289646 |
| caspase-3 activation and dna damage in pig skin organ culture after solar irradiation. | in the present study, a convenient and easy-to-handle skin organ culture was developed from domestic pig ears using polycarbonate transwell culture inserts in 12-well plate. this alternative model was then tested for its suitability in analyzing the short-term effects of a single solar radiation dose (from 55 to 275 kj.m(-2)). differentiation of the pig skin was maintained for up to 48 h in culture, and its morphology was similar to that of fresh human skin. solar irradiation induced a significa ... | 2008 | 18282184 |
| concepts for visualization of multidirectional phase-contrast mri of the heart and large thoracic vessels. | multidirectional phase-contrast magnetic resonance imaging allows the acquisition of time-resolved velocity fields (vectors) of cardiac and vascular blood flow. its unique ability to provide vectorial flow information promises to give new insights into hemodynamic physiology. however, up to now appropriate and standardized procedures and software tools are missing to take advantage of all the information contained in the data. the objective of this work is to present a new versatile software too ... | 2008 | 18280934 |
| cerebral cortical microvascular flow during and following cardiopulmonary resuscitation after short duration of cardiac arrest. | to examine changes in cerebral cortical macro- and microcirculation and their relationship to the severity of brain ischaemia during and following resuscitation from a short duration of cardiac arrest. | 2008 | 18280632 |
| development of a transoral fundoplication device and related experimental research. | this paper describes a device and surgical techniques developed between 1999 and 2003 to enable an entirely transoral approach to fundoplication. the endofundoplication system (efs) system consisted of a multifunctional flexible tube for oral introduction (18 mm) as the key component, with a specially designed retroverted grasper that was used to grasp the lower esophageal sphincter (les) area of the esophagus, for invaginating the les into the stomach and folding the gastric wall onto the wall ... | 2008 | 18270877 |
| pharmacological analyses of two naturally occurring porcine melanocortin-4 receptor mutations in domestic pigs. | the melanocortin-4 receptor (mc4r) is critical in regulating mammalian food intake and energy expenditure. numerous mutations in the mc4r gene have been identified from obese humans. so far two naturally occurring porcine mc4r (pmc4r) mutations, d298n and r236h, have been identified from various strains of pigs and d298n is being utilized as a genetic marker to screen performance traits of pigs. in this study, we performed functional analyses of pmc4r d298n and r236h, including their ligand bind ... | 2008 | 18262384 |
| a comparative study on the effects of tylosin on select bacteria during continuous flow culture of mixed populations of gut microflora derived from a feral and a domestic pig. | continuous flow cultures of feral (culture fc) and domesticated (culture rpcf) pig gut microflora were established in steady state. cultures were continuously infused with 25 or 100 microg tylosin/ml and sampled at intervals to assess effects on total culturable anaerobes, bacteroides and enterococcus via plating to agar supplemented without or with 100 microg tylosin/ml, the latter to assess bacterial sensitivity to tylosin. endogenous tylosin-insensitive anaerobes within the cultures, while si ... | 2008 | 18260812 |
| setup and dosimetry for exposing anaesthetised pigs in vivo to 900 mhz gsm mobile phone fields. | the aim of this study was a dosimetrical analysis of the setup used in the exposure of the heads of domestic pigs to gsm-modulated radio frequency electromagnetic fields (rf-emf) at 900 mhz. the heads of pigs were irradiated with a half wave dipole using three different exposure routines; short bursts of 1-3 s at two different exposure levels and a continuous 10-min exposure. the electroencephalogram (eeg) was registered continuously during the exposures to search for rf-emf originated changes. ... | 2008 | 18247366 |
| selection in the making: a worldwide survey of haplotypic diversity around a causative mutation in porcine igf2. | domestic species allow us to study dramatic evolutionary changes at an accelerated rate due to the effectiveness of modern breeding techniques and the availability of breeds that have undergone distinct selection pressures. we present a worldwide survey of haplotype variability around a known causative mutation in porcine gene igf2, which increases lean content. we genotyped 34 snps spanning 27 kb in 237 domestic pigs and 162 wild boars. although the selective process had wiped out variability f ... | 2008 | 18245828 |
| the contribution of social effects to heritable variation in finishing traits of domestic pigs (sus scrofa). | social interactions among individuals are ubiquitous both in animals and in plants, and in natural as well as domestic populations. these interactions affect both the direction and the magnitude of responses to selection and are a key factor in evolutionary success of species and in the design of breeding schemes in agriculture. at present, however, very little is known of the contribution of social effects to heritable variance in trait values. here we present estimates of the direct and social ... | 2008 | 18245326 |
| prostasome-like vesicles stimulate acrosome reaction of pig spermatozoa. | the presence of small membranous particles characterizes the male genital fluids of different mammalian species. the influence of semen vesicles, denominated prostasomes, on sperm functional properties has been well documented in humans, but their biological activity is scarcely known in other species. the present work investigated prostasome-like vesicles in pig semen for their ability to interact with spermatozoa and to affect acrosome reaction. | 2008 | 18234073 |
| snipork - a microarray of snps in candidate genes potentially associated with pork yield and quality - development and validation in commercial breeds. | snipork is an oligonucleotide microarray based on the arrayed primer extension (apex) technique, allowing genotyping of single nucleotide polymorphisms (snps) in genes of interest for pork yield and quality traits. apex consists of a sequencing reaction primed by an oligonucleotide anchored with its 5' end to a glass slide and terminating one nucleotide before the polymorphic site. extension with one fluorescently labeled dideoxynucleotide complementary to the template reveals the polymorphism. ... | 2008 | 18228175 |
| genetic imprinting of h19 and igf2 in domestic pigs (sus scrofa). | the genes insulin-like growth factor 2 (igf2) and h19 express paternally and maternally, respectively, in humans, mice, sheep, and cattle. additionally, igf2 has been shown to be regulated by at least four promoters in a tissue- or development-specific manner. in the domestic pigs, the promoter- and tissue-specific imprinting pattern of igf2 has not been well characterized, nor is the imprinting pattern of h19. in the present study, we identified two polymorphisms in each of igf2 (exons 2 and 9) ... | 2008 | 18228173 |
| a subpopulation of capsaicin-sensitive porcine dorsal root ganglion neurons is lacking hyperpolarization-activated cyclic nucleotide-gated channels. | hyperpolarization-activated cyclic nucleotide-gated (hcn) channels contribute to stabilizing resting membrane potential, thus controlling neuron excitability. subclasses of nociceptive neurons differ in their excitability, therefore, these channels could be a distinguishing marker. we investigated isolated dorsal root ganglion neurons from a non-rodent species, the pig, sus scrofa domesticus. single labeling revealed capsaicin-induced cobalt-uptake in 54.3% and transient receptor potential v1 (t ... | 2008 | 18218331 |
| bone regeneration in osseous defects-application of particulated human and bovine materials. | different bone substitute materials are used to manage the challenge of local bone loss subsequent to craniofacial reconstructive surgery. in this animal study we examined the de novo bone formation in bone defects after insertion of puros allograft of human origin or navigraft of bovine origin, and compared the regenerative potential of each material to that of autogenous bone. | 2008 | 18206408 |
| effect of liquid swine manure rate, incorporation, and timing of rainfall on phosphorus loss with surface runoff. | excessive manure phosphorus (p) application increases risk of p loss from fields. this study assessed total runoff p (tpr), bioavailable p (bap), and dissolved reactive p (drp) concentrations and loads in surface runoff after liquid swine (sus scrofa domesticus) manure application with or without incorporation into soil and different timing of rainfall. four replicated manure p treatments were applied in 2002 and in 2003 to two iowa soils testing low in p managed with corn (zea mays l.)-soybean ... | 2008 | 18178885 |
| epidemiology of trichinellosis in germany, 1996-2006. | the epidemiology of trichinellosis in germany was investigated by analyzing national surveillance data from 1996-2006. during this period, 95 laboratory-confirmed infections and 12 outbreaks were reported. the highest mean annual incidence was found in immigrants from southeast european countries (0.3 cases/100,000 vs. 0.01 cases/100,000 in the german population) with an incidence rate ratio of 26.0 (95% confidence interval 11.6-51.8). the predominant clinical symptom was muscle pain in 79 patie ... | 2008 | 18171103 |
| variability and action mechanism of a family of anticomplement proteins in ixodes ricinus. | ticks are blood feeding arachnids that characteristically take a long blood meal. they must therefore counteract host defence mechanisms such as hemostasis, inflammation and the immune response. this is achieved by expressing batteries of salivary proteins coded by multigene families. | 2008 | 18167559 |
| detection and surveillance for animal trichinellosis in gb. | the zoonotic disease trichinellosis is considered one of the re-emerging diseases with surveillance and control methods constantly gaining more importance worldwide. recent change in european union (eu) legislation introduces trichinella-free production, and the possibility of risk-based monitoring for trichinella in pigs. this has increased the role of wildlife surveillance programmes and their impact on protecting human health as well as highlighted the need for harmonised surveillance protoco ... | 2008 | 18160221 |
| laboratory and clinical development of single keyhole umbilical nephrectomy. | to describe our initial experience with single keyhole nephrectomy in a porcine model and in human subjects. | 2007 | 18158008 |
| a new device to simplify flexible endoscopic treatment of zenker's diverticulum. | endoscopic treatment of a zenker's diverticulum (zd) is challenged by maintaining a stable position and visual field. an oblique transparent cap and an overtube have been used with success. the porcine hypopharyngeal pouch is similar to a zd. while using the widespread emr device (wemr) in the esophagus, we realized that the design may be advantageous for treatment of a zd. | 2008 | 18155432 |
| [contribution to the study of cartilagines corniculata (santorini) and cuneiformis (wrisbergi) in the larynx of sus scrofa domestica]. | 1948 | 18104325 | |
| effects of ventilation with 100% oxygen during early hyperdynamic porcine fecal peritonitis. | early goal-directed therapy aims at balancing tissue oxygen delivery and demand. hyperoxia (i.e., pure oxygen breathing) has not been studied in this context, since sepsis increases oxygen radical production, which is believed to be directly related to the oxygen tension. on the other hand, oxygen breathing improved survival in various shock models. therefore, we hypothesized that hyperoxia may be beneficial during early septic shock. | 2008 | 18091553 |
| postresuscitation myocardial diastolic dysfunction following prolonged ventricular fibrillation and cardiopulmonary resuscitation. | postresuscitation myocardial dysfunction is one of the leading causes of early death after successful resuscitation from sudden death. however, the diastolic characteristics of postresuscitation myocardial dysfunction are not well defined. we therefore investigated the postresuscitation left ventricular diastolic function following prolonged cardiac arrest and subsequent cardiopulmonary resuscitation. | 2008 | 18090365 |
| electrocardiogram waveforms for monitoring effectiveness of chest compression during cardiopulmonary resuscitation. | newer guidelines address the importance of effective chest compressions, citing evidence that this primary intervention is usually suboptimally performed during cardiopulmonary resuscitation. we therefore sought a readily available option for monitoring the effectiveness of chest compressions, specifically using the electrocardiogram. | 2008 | 18090357 |
| short- and long-term effects of a novel paclitaxel coated stent in the porcine coronary model. | drug eluting stents (des) are unique in allowing sustained release for weeks after a single short intervention. the challenge with des still remaining is the combination of a biocompatible drug-eluting matrix including an antiproliferative drug showing efficacy and safety in restenosis prevention. the aim of the present animal studies was to evaluate the novel paclitaxel coated coroflex. please stent in the porcine coronary model. | 2008 | 18087665 |
| short-term effects of biocorrodible iron stents in porcine coronary arteries. | biocorrodible iron stents carry the potential to overcome limitations, such as chronic inflammation and premature recoil, posed by biodegradable polymer and magnesium alloy stents. this study aimed to test the safety and efficacy of biocorrodible iron stents in porcine coronary arteries. | 2008 | 18086136 |
| epidemiological study of hepatitis e virus infection in european wild boars (sus scrofa) in spain. | evidence of hepatitis e virus (hev) infection in spanish domestic pig has been reported and hence it was advisable to search for this zoonotic pathogen in wild boar populations. a total of 150 wild boar serum samples from eight geographic areas from south-central spain were used to investigate hev infection in european wild boar (sus scrofa) by means of serology and pcr and its distribution by age, region and management system. anti-hev igg, igm and iga were determined by an in-house elisa. the ... | 2008 | 18082340 |
| efficacy of lyophilised c-strain vaccine after oral immunisation of domestic pigs and wild boar against classical swine fever: first results. | the aim of this study was to evaluate the efficacy of lyophilised c-strain vaccine in domestic pigs and wild boar after oral application. a new spherical bait form (diameter 3 cm) containing lyophilised vaccine virus and the recent vaccine baits were used for animal experiments. four vaccination groups were established in experiment 1 (group 1: recent liquid bait vaccine; group 2: spherical baits containing one dose of the lyophilised vaccine; groups 3 (domestic pigs) and 4 (wild boar): spherica ... | 2007 | 18077931 |
| topography of the porcine epicardiac nerve plexus as revealed by histochemistry for acetylcholinesterase. | the aim of the present study was to map the topography of the porcine epicardiac nerve plexus (enp) and to re-examine the total number and distribution of the porcine intracardiac ganglia and neurons. eleven juvenile pigs (sus scrofa domestica, 3-4 weeks of age) were examined employing histochemistry for acetylcholinesterase to reveal the enp on total hearts. the nerves entered porcine epicardium at five sites: (1) ventro-medially to the origin of the superior vena cava, (2) dorsally to the orig ... | 2008 | 18063424 |
| efficacy and safety of pimecrolimus-eluting stents in porcine coronary arteries. | we aimed to evaluate an effective dosage and safety profile of pimecrolimus as an anti-inflammatory drug for drug-eluting stents. | 2007 | 18053948 |
| the morphology of the inner ear from the domestic pig (sus scrofa). | the morphology of the hair cells of the inner ear end organs from the domestic pig (sus scrofa) have been studied using a combination of scanning and transmission electron microscopy (sem and tem), revealing hair cells from the cochlea and vestibule using a novel surgical and technical approach. this is the first time that the inner ear hair cells from s. scrofa have been studied, thus providing useful anatomical information on the morphology of the hair cells from the cochlea, saccule and utric ... | 2007 | 18045329 |
| radiofrequency hepatic ablation with internally cooled electrodes and hybrid applicators with distant saline infusion using an in vivo porcine model. | radiofrequency ablation (rfa) of tumors by means of internally cooled (ice) or multitined expandable electrodes combined with infusion of saline into the tissue may improve results. our aim was to determine the efficacy of a previously optimized hybrid ice system (ice combined with infusion of saline into the tissue at a distance of 2mm) in comparison with a conventional ice cluster electrode in porcine liver in vivo. | 2008 | 18042500 |
| interstitial laser ablation of the kidney: acute and chronic porcine study using new-generation diffuser tip fiber. | many ablative techniques have been described for treatment of small renal tumors. we investigated interstitial laser ablation (ila) of porcine kidneys with a new-generation diffuser tip fiber. | 2007 | 18042035 |
| the sarcocystis-cyst containing beef and pork as the sources of natural intestinal sarcocystosis in thai people. | human intestinal sarcocystosis is a zoonotic disease caused by two coccidians, i.e. sarcocystis fusiformis (syn. s. bovihominis, s. hominis) due to consumption of raw infected beef and sarcocystis meischeriana (syn. s. suihominis) due to consumption of infected raw pork. in 1987, survey of the macroscopic s. fusiformis cysts in market beef mainly from old water buffalos aged more than 15 years were commonly observed in bangkok. in 2005, the macroscopic cyst was no longer seen in beef of cattle a ... | 2007 | 18041433 |
| assessment of global left and right ventricular function using dual-source computed tomography (dsct) in comparison to mri: an experimental study in a porcine model. | we sought to evaluate the ability of retrospectively ecg-gated dual-source computed tomography (dsct) to assess left (lv) and right ventricular (rv) functional parameters in comparison to 1.5 t magnetic resonance imaging (mri). | 2007 | 18030198 |
| a porcine deep vein thrombosis model for magnetic resonance-guided monitoring of different thrombectomy procedures. | to establish a porcine model of deep iliac vein thrombosis, which allows monitoring of thrombectomy and thrombolytic procedures by magnetic resonance imaging (mri). | 2007 | 18030194 |
| immunoglobulin light chain (igl) genes in zebrafish: genomic configurations and inversional rearrangements between (v(l)-j(l)-c(l)) gene clusters. | in mammals, immunoglobulin light chain (igl) are localized to two chromosomal regions (designated kappa and lambda). here we report a genome-wide survey of igl genes in the zebrafish revealing (v(l)-j(l)-c(l)) clusters spanning 5 separate chromosomes. to elucidate igl loci present in the zebrafish genome assembly (zv6), conventional sequence similarity searches and a novel scanning approach based on recombination signal sequence (rss) motifs were applied. rt-pcr with zebrafish cdna was used to c ... | 2008 | 18022691 |
| population phylogenomic analysis of mitochondrial dna in wild boars and domestic pigs revealed multiple domestication events in east asia. | previously reported evidence indicates that pigs were independently domesticated in multiple places throughout the world. however, a detailed picture of the origin and dispersal of domestic pigs in east asia has not yet been reported. | 2007 | 18021448 |
| survival of trichinella papuae muscle larvae in a pig carcass maintained under simulated natural conditions in papua new guinea. | in papua new guinea, trichinella papuae, a non-encapsulated species, is circulating among wild and domestic pigs and saltwater crocodiles. since an important phase of the life cycle of nematodes of the genus trichinella is the time of survival of infective larvae in decaying muscle tissues of the hosts, the carcass of a pig, experimentally infected with larvae of t. papuae, was exposed to the environmental conditions of papua new guinea to establish how long these larvae would survive and remain ... | 2007 | 18005466 |
| value of skin punch biopsies for the diagnosis of acute classical swine fever. | the objective of this study was to determine if skin punch biopsies are appropriate for the diagnosis of classical swine fever. for this purpose, 6 wild boars and 2 domestic pigs were experimentally infected with the highly virulent classical swine fever virus (csfv) koslov and 5 domestic pigs with a csfv field isolate (genotype 2.3 uelzen) derived from wild boar. skin biopsy specimens were tested using virus isolation, real-time reverse transcription polymerase chain reaction (rtrt-pcr), and fl ... | 2007 | 17998561 |
| signal transducer and activator of transcription 1 decoy oligodeoxynucleotide suppression of contact hypersensitivity. | cytokines play a pivotal role in allergy development through activating signaling mechanisms, such as the janus kinase/signal transducer and activator of transcription (stat) pathway, which controls the expression of numerous proinflammatory genes. | 2008 | 17981315 |
| composition of intestinal enterobacteriaceae populations of healthy domestic pigs. | in this study, the enterobacteriaceae microbiota, including their diversity as well as the distribution of haemolytic and virulence gene-harbouring escherichia coli of 56-day-old healthy piglets, was characterized. both the composition and the diversity of enterobacteriaceae populations varied considerably between individual pigs and intestinal sections. e. coli, enterobacter cloacae, citrobacter freundii and klebsiella pneumoniae dominated the enterobacteriaceae microbiota. however, mucosa-asso ... | 2007 | 17975092 |
| [transmission of agents of the porcine respiratory disease complex (prdc) between swine herds: a review. part 2--pathogen transmission via semen, air and living/nonliving vectors]. | the transmission of prdc-pathogens (prrsv, influenza virus a, pcv2, m. hyopneumoniae, a. pleuropneumoniae) between swine herds, which was summarized in the first part of the review, mainly occurs via pig movement. the risk of pathogen transmission by insemination with contaminated semen plays only a relevant role in the infection with prrsv and pcv2. a risk of the aerogen transmission of pathogens between herds within a distance of 2 to 3 km is described for m. hyopneumoniae and prrsv. evidence ... | 2007 | 17970334 |
| indomethacin decreases optic nerve oxygen tension by a mechanism other than cyclo-oxygenase inhibition. | we investigated the effect of several non-steroidal anti-inflammatory drugs (nsaids), on the preoptic nerve oxygen tension (onpo2), as indomethacin previously has demonstrated a strong decreasing effect on onpo2. we tested whether these nsaids, like indomethacin, also reduce the increasing effect of dorzolamide on onpo2. | 2008 | 17965100 |
| a lightweight, partially absorbable mesh (ultrapro) for endoscopic hernia repair: experimental biocompatibility results obtained with a porcine model. | a meticulous surgical technique, a mesh of adequate dimensions, and use of a mesh with good biocompatibility properties are decisively important for minimizing the development of recurrences after endoscopic hernia repair surgery. mesh "shrinkage" is a function of the mesh's biocompatibility, that is, the properties of the mesh. large-pore, lightweight polypropylene meshes possess the best biocompatibility, and the newly developed meshes meet these requirements. | 2008 | 17963002 |
| chromosomal instability in afrotheria: fragile sites, evolutionary breakpoints and phylogenetic inference from genome sequence assemblies. | extant placental mammals are divided into four major clades (laurasiatheria, supraprimates, xenarthra and afrotheria). given that afrotheria is generally thought to root the eutherian tree in phylogenetic analysis of large nuclear gene data sets, the study of the organization of the genomes of afrotherian species provides new insights into the dynamics of mammalian chromosomal evolution. here we test if there are chromosomal bands with a high tendency to break and reorganize in afrotheria, and b ... | 2007 | 17958882 |