Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
|---|
| proceedings: immunity to trichuris muris in mice infected with trichinella spiralis. | 1974 | 4419390 | |
| trichinella spiralis: phospholipase in challenged mice and rats. | 1974 | 4416738 | |
| trichinella spiralis: peroxidase activity in isolated cells from the rat intestine. | 1974 | 4416737 | |
| immunosuppressive activity of azathioprine in experimental infection of the mouse with trichinella spiralis (nematoda). | 1974 | 4413782 | |
| effects of mebendazole on the encysted phase of trichinella spiralis in the rat: an electron-microscope study. | 1974 | 4413153 | |
| [elimination of microorganisms from trichinella spiralis larva]. | 1973 | 4376206 | |
| synergistic interaction of two agents in mice: japanese b encephalitis virus and trichinella spiralis. | 1974 | 4361706 | |
| immunosuppression and increased susceptibility to japaneses b encephalitis virus in trichinella spiralis-infected mice. | 1973 | 4350788 | |
| histopathological and histochemical investigations on trichinella spiralis-infected mice after res stimulation. | 1971 | 4334363 | |
| histochemical investigations on the activity of some phosphatases in skeletal muscles of mice under the influence of infection with trichinella spiralis. | 1971 | 4325754 | |
| comparative effects of cortisone and acth on golden and chinese hamsters infected with trichinella spiralis. | 1968 | 4319345 | |
| [behavior of trichinella spiralis capsulae after acth treatment]. | 1966 | 4289085 | |
| persistance of adult trichinella spiralis in pertussis-treated mice. | 1966 | 4288777 | |
| nature of the cyst of trichinella spiralis. | 1966 | 4286377 | |
| [effect of piperazine (hexahydropyrazone) on various developmental stages of trichinella spiralis (owen) in experimentally infected mice]. | 1964 | 4283997 | |
| [simultaneous infestation with the nematodes trichinella spiralis and diocto-phyme renale in a wolf]. | 1972 | 4265880 | |
| a digest compressorium technique for detection of trichinella spiralis larvae. | 1972 | 4259933 | |
| transformation of lymphocytes from animals sensitized to trichinella spiralis. | 1971 | 4256095 | |
| delayed hypersensitivity and humoral antibodies in guinea pigs sensitized with trichinella spiralis antigens. | 1971 | 4255329 | |
| delayed hypersensitivity to trichinella spiralis. 3. effect of repeated sensitizations in donors and recipients. | 1970 | 4246565 | |
| histochemical study of drug effects on mic infected with trichinella spiralis. | 1967 | 4229810 | |
| the transmission of hog cholera virus by trichinella spiralis larvae. | studies have been carried out to determine (a) the possible role of t. spiralis larvae in the transmission of hog cholera virus and (b) to determine the effect of elevated swine temperature on the viability of trichinae. trichina larvae from hog cholera infected swine were freed from diaphragmatic tissue by artificial digestion. washed and disinfected larvae transmitted hog cholera virus while the supernatant digestive fluid did not transmit the virus. infectivity of the virus was lost when the ... | 1966 | 4223754 |
| effect of immune rabbit igg on the primary immune response to trichinella spiralis in mice. | 1974 | 4206884 | |
| decreased susceptibility to listeria monocytogenes in mice after infection with trichinella spiralis. | mice challenged intravenously with listeria monocytogenes at 7 or 21 days after trichinella spiralis infection demonstrated a higher mean lethal dose and longer survival time than normal mice. this effect of helminthic infection was abrogated after 49 days. | 1974 | 4205953 |
| the structure and composition of the capsule of trichinella spiralis in host muscle. | 1970 | 4193472 | |
| the importance of the biopsy in the diagnosis of the trichinella spiralis infection. | 1970 | 4192464 | |
| search of quick method of contrast staining of trichinella spiralis larvae in muscles. | 1970 | 4192463 | |
| mouse transplantation immunity depressed by trichinella spiralis. | 1969 | 4184232 | |
| inhibition of trichinella spiralis complement fixation by immune macroglobulin. | 1968 | 4177757 | |
| adsorption of globulin to the cuticle of larvae and adults of trichinella spiralis. | 1967 | 4169236 | |
| chemotactic response of polymorphonuclear leukocytes to trichinella spiralis and ascaris suum extracts. | 1965 | 4158486 | |
| amine excretion in excysted larvae and adults of trichinella spiralis. | 1973 | 4147932 | |
| trichinella spiralis: immunologic response to infection in mice. | 1972 | 4114792 | |
| trichinella spiralis and schistosoma mansoni: specificity of in vitro, leukocyte-mediated histamine release from rabbit platelets. | 1971 | 4104100 | |
| studies on the immunologic host-parasite relationships. ii. comparative electrophoretic and immunoelectrophoretic studies on experimental trichinella spiralis infection in swine and sheep. | 1971 | 4103612 | |
| the effects of trichinella spiralis infection of pregnant mice on the future behavior of their offspring. | trichinella spiralis infections in pregnant mice had both pre- and post-natal effects on the future behavior of the offspring. young, born of infected and reared by uninfected mothers as well as young born of uninfected and reared by infected mothers, were behaviorally distinguishable from controls that were born and reared by uninfected mothers when assessed by their tendency to emerge from their home cages into an unfamiliar open-field arena. the pre- and post-natal effects appeared to be addi ... | 1985 | 4093811 |
| cell injury caused by trichinella spiralis in the mucosal epithelium of b10a mice. | most of the mucosal epithelium in the anterior small intestine of b10a mice infected with trichinella spiralis showed no cytopathology. however, isolated foci of damaged cells or dense masses of multinucleate cytoplasm were seen in the crypt-villus junction, or the base of the villi. cells occupied by the nematode ranged from a nearly normal appearance, showing only compressed nuclei and organelles, to progressive inflation and vesiculation of endoplasmic reticulum, loss of terminal web and henc ... | 1985 | 4093809 |
| vaccination against the gastrointestinal helminths trichinella spiralis and hymenolepis nana: relationship between routes of immunization and effective protection. | mice immunized with antigens derived from trichinella spiralis muscle larvae or hymenolepis nana embryos were found to be protected against the homologous challenge infection. intraperitoneal route was found the most effective in stimulating protection compared with subcutaneous or intravenous administration. even a single dose of antigen administered intraperitoneally stimulated a significant protection. the results of our experiments confirm that the route of administration has a noteworthy in ... | 1985 | 4091979 |
| effect of clofibrate on the endogenous cycle of trichinella spiralis and trichinella nelsoni. | 1985 | 4072224 | |
| [value of various microelements in the course of trichinella spiralis infection in mice]. | 1985 | 4072221 | |
| [basophilic transformation of the muscle cells of mice during infection with trichinella spiralis larvae. i. intramuscular (synchronous) infection with larvae of various developmental stages]. | 1985 | 4072219 | |
| [monoamine oxidase (mao) activity in the blood and homogenates of the spleen, mesenteric lymph node and small intestine of mice with experimental trichinella spiralis infection]. | 1985 | 4072215 | |
| comparative study of the fatty acids of trichinella spiralis, trichinella nativa and trichinella nelsoni. | 1985 | 4072214 | |
| succinate dehydrogenase and fumarate reductase activity in trichinella spiralis and the mode of action of some anthelmintics. | 1985 | 4072213 | |
| compared genetic distance between trichinella spiralis and other trichinellae isolations by several immunization path-ways. | 1985 | 4072212 | |
| prolonged expulsion of adult trichinella spiralis and eosinophil infiltration in mast cell-deficient w/wv mice. | eosinophil infiltrations were observed in the intestine and the muscle of both trichinella spiralis-infected (wbxc57bl/6)f1-w/wv mice and their littermates, wbb6f1-+/+, +/w, +/wv, almost to the same extent. w/wv mice did not show infiltration of subepithelial mast cells and globule leucocytes in response to t. spiralis infection. increased numbers of these cells were observed in their littermates. worms in w/wv mice were retained for longer periods than those in littermates. also, no difference ... | 1985 | 4067246 |
| trichinella spiralis in wild animals, cats, mice, rats and farmed fur animals in finland. | a total of 1 399 samples of wild animals, cats, mice, rats and fur animals were examined for trichinella larvae during the period 1.1.1982-30.6.1984. samples were obtained both from the problem area, were trichinella larvae had been found in pigs, and for comparison from the rest of finland. the frequency of the infection in wild carnivores, badgers, pine martens, raccoon dogs, foxes and wild mink was significantly higher in the problem area than in the rest of finland. | 1985 | 4059043 |
| comparison of immune effects in mice immunized with trichinella spiralis adult and larval antigens. | 1985 | 4057011 | |
| the use of enzyme polymorphisms to identify genetic differences in the genus trichinella. | seven isolates of the genus trichinella were evaluated for their genetic identity and variability using starch gel electrophoresis. the various strains exhibited polymorphism in 8 of 11 enzyme systems tested and the strains could be segregated into at least 3 basic patterns for geographical isolates of trichinella: pigs, wild carnivores and trichinella spiralis var. pseudospiralis. there was also evidence for further differences between isolates from wild carnivores. the isozyme technique appear ... | 1985 | 4057010 |
| genetic control of immunity to trichinella spiralis in mice: capacity of cells from slow responder mice to transfer immunity in syngeneic and f1 hybrid recipients. | mice of the c57bl/10 (b10) strain are slow responders to infection with t. spiralis in terms of ability to expel worms from the intestine. compared with rapid-responder nih mice, infection stimulates a slower and reduced blast cell response in the draining mesenteric lymph node (mln). transfer of immune cells from the mln (mlnc) does not accelerate worm expulsion from naive b10 recipient mice, even though mlnc from this strain effectively transfer immunity to (b10 x nih) f1 recipients. in common ... | 1985 | 4054943 |
| [therapeutic efficacy of mebendazole and pyquiton against trichinella spiralis in mice]. | 1985 | 4053326 | |
| swine trichinosis in new england slaughterhouses. | diaphragms of 5,315 slaughter hogs from the new england states were examined for trichinella spiralis infection between june 22 and dec 22, 1983. thirty-nine hogs (0.73%) were infected. the infections were light, none exceeding 30 larvae/g of tissue, with an arithmetic mean of 4.7 larvae/g. infected hogs originated from 5 of 6 new england states. the widespread occurrence of porcine trichinosis in new england indicates that the small or part-time hog farming operations frequently found in this r ... | 1985 | 4051306 |
| in vitro cellular immune response in mice and rabbits immunized with trichinella spiralis antigen. | the possibility of using cell mediated immune response as a diagnostic tool has been investigated with t. spiralis laboratory/model. the feasibility of a in vitro microculture method to measure blast cell activity of lymphoblasts in mice experimentally infected with t. spiralis muscle larvae or immunized with soluble crude antigen and the lymphoproliferative response in immunized rabbits was demonstrated. the obtained results suggest that the cell mediated immune response from blood lymphocytes ... | 1985 | 4041244 |
| life-phase specific induction and expression of rapid expulsion in rats suckling trichinella spiralis-infected dams. | rat dams infected with 1000 trichinella spiralis muscle larvae, 4 weeks prior to breeding, provided their suckling offspring with immunity to challenge with 200 muscle larvae at 2 weeks of age. the immunity was expressed in the elimination of 75-99% of the challenge dose within 24 hr. the intestinal worm burden did not decline significantly after the initial expulsion. infected dams continued to protect their offspring during three breeding cycles, for as long as 26 weeks after infection. immuni ... | 1985 | 4040119 |
| adoptive transfer of immunity to trichinella spiralis in mice: generation of effective cells by different life cycle stages. | 1985 | 4039708 | |
| evaluation of a purified schistosoma japonicum glycoprotein egg antigen for the immunodiagnosis of infection in man. | a purified glycoprotein, glycoprotein-2, which was isolated from schistosoma japonicum soluble egg antigen, was tested in an enzyme-linked immunoadsorbent assay for its potential as an immunodiagnostic reagent. using empirically-derived criteria of endpoint titer, 39/40 sera from s. japonicum-infected individuals were scored correctly as positive in a blind test. of these, 26/40 were from individuals who excreted fewer than 100 eggs per gram of stool. no cross reactions were observed with sera f ... | 1985 | 4038590 |
| phosphatidylethanolamine methylation in intestinal brush border membranes from rats resistant to trichinella spiralis. | methylation of phospholipids is proposed as a mechanism to explain changes in properties of intestinal brush border membrane that coincide with development of immunity to the intraepithelial parasite, trichinella spiralis. methylation was measured by the incorporation of the [3h]methyl group from s-adenosyl-l-[3h]methyl methionine into phospholipids. at least two enzymatic components were detected that converted phosphatidylethanolamine to phosphatidylcholine. the first, designated methyltransfe ... | 1985 | 4033691 |
| immunization with purified antigens protects mice from lethal infection with trichinella spiralis. | 1985 | 4032155 | |
| attempts to manipulate specific responses to induce resistance to schistosoma mansoni in kenyan baboons (papio anubis). | attempts were made to manipulate specific responses of baboons to protect them from infection with schistosoma mansoni. in experiment 1, eosinophilia was induced in naive baboons with trichinella spiralis larvae given intravenously before intraperitoneal injection of globulin fractions from s. mansoni-infected baboon sera and subsequent percutaneous exposure to s. mansoni cercariae. in experiment 2, baboons with 8- or 32-week-old primary s. mansoni infections received t. spiralis i.v. before an ... | 1985 | 4031458 |
| immune responses to trichinella pseudospiralis and trichinella spiralis in mice. | 1985 | 4030207 | |
| the effect of dosage regimen on the efficacy of cambendazole against trichinella spiralis. | 1985 | 4030205 | |
| trichinella spiralis: nonspecific resistance and immunity to newborn larvae in inbred mice. | the implantation and development of intravenously injected trichinella spiralis newborn larvae were examined in different strains of inbred mice by determining muscle larvae burden. this was compared to the numbers of muscle larvae that established after a natural infection during which a quantitative assessment of intestinal newborn larvae production was made. in most inbred strains of mice, newborn larvae do not all successfully implant in muscle. mice of the dba/1 strain are the most resistan ... | 1985 | 4018217 |
| a freeze-fracture study of the digestive tract of the parasitic nematode trichinella. | freeze-fracture preparations of the esophagus and intestine of larvae and adults of the nematode trichinella spiralis illustrate the distribution of intramembranous particles in membranes of a number of cell types, and several specializations were found. esophageal glands are prominently linked by gap junctions, but gap junctions were not found between intestinal cells. muscle cells of the esophagus have rectilinear arrays of particles, thought to be points of adherence of the muscles to the eso ... | 1985 | 4012758 |
| trichinella spiralis: acquired immunity in swine. | the ability of domestic pigs to develop protective immunity to trichinella spiralis in response to inoculation with different doses of muscle larvae was assessed. adult worms developing from the inoculations of 112, 500, and 10,000 larvae were expelled from the intestine about 6 weeks after inoculation. inoculation with 25,000 larvae, however, resulted in more rapid intestinal worms expulsion, indicating that gut expulsion is dose dependent. secondary expulsion also tended to be dependent upon p ... | 1985 | 3996525 |
| prevalence of trichinosis in southern louisiana swine. | after an outbreak of human trichinosis in louisiana involving 45 cases and 1 death in 1979 and 1980, a survey of pigs killed in 21 selected small slaughterhouses in southwestern louisiana was conducted from november 1980 to september 1981. the sera from 1,225 pigs were examined for trichinella antibodies using an enzyme-linked immunosorbent assay (elisa); 1,223 diaphragms were subjected to peptic digestion and examined for the presence of trichinella spiralis larvae. one diaphragm (0.08%) was fo ... | 1985 | 3994113 |
| infectivity of canadian isolates of trichinella spiralis nativa for swine, rats and carnivores. | the infectivity of trichinella spiralis nativa isolates from widely separated geographic areas of canada was determined by feeding infected musculature to swine, laboratory rats and carnivores (cats, foxes, ferrets). low infectivity for swine and rats and high infectivity for carnivores were observed. light infections were established in four of 16 swine examined between 25 and 53 days postinfection. feeding of infected porcine musculature to ferrets demonstrated that trichinella spiralis nativa ... | 1985 | 3986683 |
| anaphylactic-like reaction of small intestinal epithelium in parasitized guinea-pigs. | antigens derived from trichinella spiralis were used to challenge, in vitro, sensitized jejunum from infected guinea-pigs while monitoring ion transport properties of the tissue. antigen challenge resulted in dose-dependent increases in trans-epithelial electrical potential difference and short circuit current. both antigen-stimulated electrical alterations and schultz-dale contractions were demonstrated in small intestinal tissue after the passive transfer of immune serum containing anti-trichi ... | 1985 | 3972439 |
| effects on trichinella spiralis of host responses to purified antigens. | purification of two antigens (48-kilodalton polypeptide and a group with major subunits of 50 and 55 kilodaltons) from the infective larvae of the parasitic nematode trichinella spiralis was recently reported. immunization of mice with either of these antigens induces strong resistance to a subsequent challenge infection. in the study reported here the mechanism of this resistance was investigated by monitoring the parasite's life cycle in mice immunized with the antigens. immunized mice were ab ... | 1985 | 3969571 |
| a tongue biopsy technique for the detection of trichinosis in swine. | a tongue biopsy technique developed for the detection of trichinella spiralis infection in swine involves taking a deep core biopsy of the tongue musculature, and examination of the sample by digestion. using this procedure, 31 of 52 (60%) swine from an indiana herd were found to be infected with t. spiralis. the average biopsy weighed 0.42 g, and the intensity of infection averaged 180 larvae per gram (range 2-1157). the biopsy was quick and easy to perform and the tongues healed well following ... | 1986 | 3962157 |
| inhibition of passive systemic anaphylaxis in guinea pigs by trichinella spiralis infection. | thirty of 33 guinea pigs experimentally infected with trichinella spiralis survived passive systemic anaphylactic reactions which were fatal for 32 of 33 uninfected controls. guinea pigs were infected with viable excysted trichinella larvae 20 to 32 days before they and uninfected controls were sensitized by intracardiac injection of rabbit anti-bovine serum albumin. animals were challenged 24 hours later by intracardiac injection of bovine serum albumin. respiratory anaphylaxis was observed in ... | 1986 | 3952981 |
| trichinella spiralis in the black bear (ursus americanus) of pennsylvania: distribution, prevalence and intensity of infection. | samples of tongue or diaphragm from 2,056 black bears harvested in pennsylvania during the 1981-1983 hunting seasons were examined for larvae of trichinella spiralis by peptic digestion. sixteen males and 21 females were infected. the overall prevalence of infection was 1.8%. infected animals were distributed widely throughout the range of the bear in pennsylvania. in samples from infected bears, the geometric mean density of muscle larvae was 7.8 per g of tissue (lpg). there were neither sex- n ... | 1986 | 3951059 |
| trichinella spiralis: newborn larval migration route in rats reexamined. | the route by which trichinella spiralis newborn larvae migrate from the small intestine to striated muscle was studied in inbred ao and random-bred sprague-dawley rats. newborn larvae were quantitatively recovered from the thoracic duct lymph, peritoneal cavity, and hepatic portal vein blood during the course of a primary infection with 4000 muscle larvae. the total recovery of newborn larvae assessed in this manner was compared with the number of muscle larvae in control rats receiving the same ... | 1986 | 3943594 |
| immunity to onchocerca lienalis microfilariae in mice. ii. effects of sensitization with a range of heterologous species. | the model of onchocerca lienalis microfilariae (mff) injected into cba and t.o. strains of mice has been used to examine immunity to skin-dwelling microfilariae following exposure to a range of species of helminths. mice which had received a primary infection with o. cervicalis mff were significantly resistant to challenge with o. lienalis mff (58% reduction relative to challenge controls). immunization with the uterine contents (eggs and mff) of o. lienalis, o. gutturosa or o. volvulus conferre ... | 1985 | 3937854 |
| eosinophil adherence to infective larvae of trichinella spiralis: quantification and modulation. | eosinophils play an important role in host defence against helminthic infection. a quantitative system for studying the interactions of eosinophils and a large non-ingestible target was developed using infective muscle-stage larvae of trichinella spiralis. at 37 degrees, this antibody-dependent system provided a reliable, reproducible index of eosinophil function. adherence was equivalent under aerobic and anaerobic conditions. no significant differences were noted between peritoneal exudate eos ... | 1985 | 3932192 |
| [150th anniversary of the discovery of the parasite trichinella spiralis. aspects in the evolution of our knowledge of t. spiralis and trichinelliasis]. | 1985 | 3903953 | |
| glycosidases of trichinella spiralis. | the exoglycosidases beta-n-acetyl-d-glucosaminidase, beta-n-acetyl-d-galactosaminidase, alpha-1-fucosidase, alpha-d-glucosidase and alpha-d-mannosidase, and a non-specific acid phosphohydrolase are present at high levels in extracts of adult and muscle-stage (l1) trichinella spiralis and at lower (5-30-fold) levels in extracts of the newborn larvae. the enzyme activities from the l1 extract were characterized. all displayed maximum activity at acid ph. beta-n-acetyl-d-glucosaminidase and beta-n- ... | 1985 | 3897859 |
| preparation of antibodies to guinea pig ige and its use for enzyme-linked immunosorbent assay of ige antibodies. | guinea pigs were infected with trichinella spiralis. a pooled serum from the infected guinea pigs was fractionated by deae-cellulose column chromatography and sephadex g-200 gel filtration. an ige-rich fraction was injected into rabbits. the antiserum from the rabbits, after appropriate absorption with a normal guinea pig plasma, formed a precipitin line in immunoelectrophoresis and in immunodiffusion against a guinea pig serum containing ige antibodies to ovalbumin. uptake of 125i ovalbumin was ... | 1985 | 3894244 |
| effects of macrophage activity on the antibody-dependent cytotoxicity against trichinella spiralis newborn larvae: an in vitro cytotoxicity and ultrastructural study. | the effect of the activity of macrophages on the antibody-dependent cytotoxicity against trichinella spiralis newborn larvae was studied in vitro. macrophages present in peritoneal exudates from mice genetically selected for high and low antibody production (hl and ll, respectively) showed an inverse cytotoxic effect. cells from hl mice were ineffective, whereas cells from ll mice had a very high killing capacity. ultrastructural studies of cells after incubations of up to 36 h supported these o ... | 1985 | 3887792 |
| antigen production by encysted muscle larvae of trichinella spiralis. | the production of excretory-secretory antigens by encysted muscle larvae of trichinella spiralis has been investigated immuno-histochemically using an antiserum raised by infection in rabbits and purified both before and after conjugation by ion-exchange chromatography. the specificity of the antibody for excretory-secretory products was demonstrated by the pattern of staining of live worms in vitro and the failure of the labelled antibody to stain dead, non-metabolizing worms. using this labell ... | 1985 | 3886777 |
| superiority of the elisa technique over parasitological methods for detection of trichinellosis in slaughtered pigs in canada. | trichinoscopic examination, pepsin-hydrogen chloride digestion and the elisa assay were used in an epidemiological survey for the presence of trichinella spiralis in slaughterhouse pigs over a period of 12 months. the first two methods failed to detect any cases of trichinellosis in sows aged between two to three years. the elisa assay, however, detected a 2.5% prevalence amongst the 2046 blood specimens tested. foci of t. spiralis are localized in certain regions only. the discrepancy between t ... | 1985 | 3886108 |
| the effect of dimethylnitrosamine on host resistance and immunity. | adult female b6c3f1 mice were injected ip with 0.2 ml phosphate-buffered saline (pbs) only or pbs containing 1.5, 3, or 5 mg dimethylnitrosamine (dmn)/kg body wt daily for 14 days. on day 16, mice were evaluated for changes in immune status as measured by the antibody response to sheep red blood cells (srbcs), blastogenesis to t- and b-cell mitogens, natural killer (nk) cell function, delayed hypersensitivity, and alveolar macrophage (am) bactericidal activity; and for changes in host resistance ... | 1985 | 3883572 |
| l3t4-positive t lymphoblasts are responsible for transfer of immunity to trichinella spiralis in mice. | the characteristics of lymphocyte subpopulations involved in mediating immunity to the intestinal nematode trichinella spiralis in vivo have been examined using adoptive transfer in conjunction with accurate cell-sorting and cell-depletion techniques. positive selection of cell subsets, using facs sorting and velocity sedimentation at unit gravity, confirm that rapidly dividing t blasts are the major population that mediates expulsion of the worm from the gut. furthermore, cell-depletion studies ... | 1985 | 3876979 |
| efficacy of ivermectin against trichinella spiralis in mice. | 1985 | 3840934 | |
| trichinosis in thailand during 1962-1983. | various studies on trichinosis in thailand since the first outbreak in 1962 up until 15 july 1983 are reviewed. there were 67 outbreaks, affecting 2,792 persons and resulting in 85 deaths. most of the outbreaks occurred in the north of the country which is mountainous. hilltribe pigs and wild boars were the common sources of human infection. incidence of trichinella spiralis larvae in dog meat in the area favoring of dog meat consumption is cautioned to create a public health problem in the futu ... | 1985 | 3836212 |
| comparative efficacy of ketoconazole and mebendazole in experimental trichinosis. | the therapeutic efficacy of ketoconazole and mebendazole was studied in icr/cd-1 mice infected with trichinella spiralis for 17 to 20 weeks. efficacy of both drugs was over 70% when compared with results in control mice. this study indicates that both ketoconazole and mebendazole should be considered in the treatment of trichinosis in humans. | 1986 | 3813518 |
| anaphylaxis-mediated epithelial cl- secretion and parasite rejection in rat intestine. | immunologically mediated expulsion of trichinella spiralis infective larvae in the rat was used as a model to test the hypothesis that intestinal anaphylaxis induced by parasite antigen causes ion transport alterations in small intestinal epithelium, and that the small intestinal epithelium, by altering its physiologic state in response to mast cell-derived mediators, functions as an effector tissue in the expulsion process. experimental results demonstrated that the rapid rejection response and ... | 1987 | 3805721 |
| the ig class distribution of anti-phosphoryl choline responses in mice infected with parasitic nematodes. | the anti-phosphoryl choline antibody responses of resistant and susceptible strains of mice infected with microfilariae of dipetalonema viteae or the gastrointestinal nematode parasite trichinella spiralis were determined. the responses were characterized both in terms of their kinetics and the constituent role played by each immunoglobulin heavy-chain class. infection with either parasite elicited detectable responses in all strains investigated. however, the kinetics of the response of each he ... | 1986 | 3804381 |
| trichinella spiralis: immunization of pigs with newborn larval antigens. | the potential of crude trichinella spiralis newborn larval antigens for pig immunization was investigated. a preparation of whole newborn larvae killed by freezing and thawing, and combined with freund's complete adjuvant, induced a high level of protection against challenge (78%), compared to a 40% resistance level in pigs immunized with excretory secretory antigens of muscle larvae. sera from pigs immunized with newborn larvae contained antibodies which bound to the surface of the newborn larv ... | 1987 | 3803533 |
| glucose absorption in vitro by the enteric stages of trichinella spiralis. | absorption of glucose in vitro by enteric stages of trichinella spiralis was examined in worms isolated at different times following infection. glucose absorption by 6-h-old worms was similar to that seen during moulting (24 h post-infection (p.i.]. as embryogenesis began (48 h p.i.) glucose absorption in vitro by the parasite rose dramatically to a peak in 72-h-old worms. absorption of glucose in vitro remained high in 96-h-old worms but as larviposition began (120 h p.i.) glucose uptake by t. ... | 1986 | 3797065 |
| blast cell activity in mice infected with hymenolepis nana, h. diminuta and trichinella spiralis: in vivo uptake of 125iudr in lymphoid tissues and gut. | the kinetics of the lymphoblast response in mice during the course of a primary infection with hymenolepis nana was measured by the in vivo uptake of 125iudr. the response was most marked in tissues local to the site of infection, involving the nodes draining the small intestine but not other areas, e.g., inguinal lymph nodes. a close correlation between these responses and the course of infection was observed. uptake of 125iudr was greatest in the mesenteric lymph node (mln) but the peak reache ... | 1986 | 3794296 |
| inoculation of pigs against trichinella spiralis, using larval excretory-secretory antigens. | pigs were inoculated with trichinella spiralis excretory-secretory products derived from short-term in vitro maintenance of infective muscle larvae. intraperitoneal administration of excretory-secretory products in freund's complete adjuvant or aluminum hydroxide induced moderate, but variable, degrees of immunity to challenge exposure in a nondose-dependent manner; im administration of products in freund's incomplete adjuvant was less successful. inoculated pigs harbored fewer adult worms, and ... | 1986 | 3789502 |
| influence of vitamin c on the resistance of rats to trichinella spiralis infection. | 1986 | 3788172 | |
| the enzyme-linked immunosorbent assay (elisa) for determination of specific antibodies in mice infected with trichinella spiralis or trichinella pseudospiralis. | 1986 | 3788171 | |
| circulating immune complexes in mice infected with trichinella spiralis. | 1986 | 3788170 | |
| eosinophils and mononuclear cells as effector cells in a trichinella spiralis infection; cell biological and biochemical aspects and the use of biological response modifiers. | 1986 | 3788168 | |
| the role of malic enzyme in the carbohydrate metabolism of trichinella spiralis spiralis and trichinella spiralis pseudospiralis. | 1986 | 3781727 | |
| trichinella spiralis: vascular recirculation and organ retention of newborn larvae in rats. | the recirculation of trichinella spiralis newborn larvae was studied in inbred ao rats. newborn larvae collected after in vitro incubation of adult t. spiralis worms for 2 or 24 hr were injected into rats through the tail vein or hepatic portal vein. blood samples from the femoral vein, hepatic portal vein, and abdominal aorta were collected at intervals from 1 min to 24 hr after larval injection. newborn larvae of both ages (24 hr or 2 hr old) persisted in femoral vein blood for less than or eq ... | 1986 | 3780936 |
| trichinella spiralis: antifecundity and antinewborn larvae immunity in swine. | the development of antifecundity and antinewborn larvae immunity in swine infected with trichinella spiralis was investigated. in primary infections, adult female worm fecundity dropped sharply after 3 weeks, although adults could be recovered from the small intestine for at least 7 weeks after infection. in challenge infections of pigs infected previously, adult female worm fecundity was depressed up to 51% and the adults were expelled within 3 weeks. since immune pigs are almost completely res ... | 1986 | 3780929 |
| evaluation of different antigens in a seroepizootiological survey of trichinellosis by enzyme-linked immunosorbent assay. | antigen isolated from the large-particle fraction of the muscle trichinella spiralis larvae (paw), excretory/secretory (e/s) and crude worm extract (cwe) antigens were evaluated in a seroepizootiological survey of trichinellosis by the enzyme-linked immunosorbent assay (elisa). the elisa using paw antigen yielded 16 positive animals (1.6%), e/s antigen revealed 21 (2.1%) positive, and the highest number of positive (23 or 2.3%) were obtained using cwe antigen. parasitological post-mortem examina ... | 1986 | 3776080 |
| limit dilution analysis of mast cell precursor frequency in the gut epithelium of normal and trichinella spiralis infected mice. | previous studies have established that the gut nematode trichinella spiralis induces a dramatic thymus dependent intestinal mastocytosis which peaks within 6 to 12 days after primary oral infection. it is not known, however, if the increase in gut mast cells results from the influx of mast cells or their precursors, or from the expansion and differentiation of mast cell precursors (mcp) that are normally present in the small intestinal epithelium. in the present study, the number of mucosal mcp ... | 1986 | 3774378 |