Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
|---|
| molecular magnetic resonance imaging of deep vein thrombosis using a fibrin-targeted contrast agent: a feasibility study. | to evaluate the value of a fibrin-specific mr contrast agent (ep-2104r; epix pharmaceuticals) for detection of deep vein thrombosis (dvt) and monitoring of percutaneous intervention for treatment. | 2009 | 19151606 |
| bama miniature pigs (sus scrofa domestica) as a model for drug evaluation for humans: comparison of in vitro metabolism and in vivo pharmacokinetics of lovastatin. | the objective of this study was to demonstrate that bama miniature pigs are a suitable experimental animal model for the evaluation of drugs for man. to this end, in vitro lovastatin metabolism at the minipig liver microsomal level and in vivo pharmacokinetics were studied. results were compared with those obtained from humans. our data indicate that the main metabolites and enzyme kinetic parameters of lovastatin metabolism are similar in pigs and humans. triacetyloleandomycin, a specific inhib ... | 2008 | 19149415 |
| the adult göttingen minipig as a model for chronic heart failure after myocardial infarction: focus on cardiovascular imaging and regenerative therapies. | porcine models have become increasingly popular in cardiovascular research. the standard farm pig rapidly increases in body weight and size, potentially confounding serial measurements of cardiac function and morphology. we developed an adult porcine model that does not show physiologic increases in heart mass during the study period and is suitable for long-term study. we compared adult minipigs with the commonly used adolescent yorkshire swine. myocardial infarction was induced in adult göttin ... | 2008 | 19149414 |
| contrasting mode of evolution at a coat color locus in wild and domestic pigs. | despite having only begun approximately 10,000 years ago, the process of domestication has resulted in a degree of phenotypic variation within individual species normally associated with much deeper evolutionary time scales. though many variable traits found in domestic animals are the result of relatively recent human-mediated selection, uncertainty remains as to whether the modern ubiquity of long-standing variable traits such as coat color results from selection or drift, and whether the unde ... | 2009 | 19148282 |
| diversification of porcine mhc class ii genes: evidence for selective advantage. | the major histocompatibility complex (mhc) is an immunological gene-dense region of high diversity in mammalian species. sus scrofa was domesticated by at least six independent events over eurasia during the holocene period. it has been hypothesized that the level and distribution of mhc variation in pig populations reflect genetic selection and environmental influences. in an effort to define the complexity of mhc polymorphisms and the role of selection in the generation of class ii gene divers ... | 2009 | 19142631 |
| epidemiology, diagnosis, treatment, and control of trichinellosis. | summary: throughout much of the world, trichinella spp. are found to be the causative agents of human trichinellosis, a disease that not only is a public health hazard by affecting human patients but also represents an economic problem in porcine animal production and food safety. due to the predominantly zoonotic importance of infection, the main efforts in many countries have focused on the control of trichinella or the elimination of trichinella from the food chain. the most important source ... | 2009 | 19136437 |
| drug-eluting balloon: very short-term exposure and overlapping. | paclitaxel balloon coating has shown promising effects in inhibiting restenosis in initial clinical trials. the aim of the present study was to evaluate the influence of two critical features of drug-eluting balloon (deb) application - inflation time and increased dose due to overlapping balloons. fifty-six stainless steel stents were implanted in the left anterior descending and circumflex coronary arteries of 28 domestic pigs using a 1.2:1.0 overstretch ratio. stents were mounted on convention ... | 2009 | 19132209 |
| porcine reproductive and respiratory syndrome virus (prrsv) infection in wild boars. | the porcine reproductive and respiratory syndrome (prrs) is one of the economically most important swine diseases worldwide. the virus can be spread by viraemic and persistent infected pigs. spread and infection are advanced in areas with high herd and population densities. as wild boars have been found seropositive for prrsv in germany, france, and the usa, exchange between wild and domestic pig populations may exist. however, comprehensive information on prrsv infection in wild boars is presen ... | 2009 | 19131188 |
| validation of a western blot for the detection of anti-trichinella spp. antibodies in domestic pigs. | trichinellosis is a zoonotic disease in humans caused by trichinella spp. according to international regulations and guidelines, serological surveillance can be used to demonstrate the absence of trichinella spp. in a defined domestic pig population. most enzyme-linked immunosorbent assay (elisa) tests presently available do not yield 100% specificity, and therefore, a complementary test is needed to confirm the diagnosis of any initial elisa seropositivity. the goal of the present study was to ... | 2009 | 19130084 |
| first magnetic resonance imaging-guided aortic stenting and cava filter placement using a polyetheretherketone-based magnetic resonance imaging-compatible guidewire in swine: proof of concept. | the purpose of this study was to demonstrate feasibility of percutaneous transluminal aortic stenting and cava filter placement under magnetic resonance imaging (mri) guidance exclusively using a polyetheretherketone (peek)-based mri-compatible guidewire. percutaneous transluminal aortic stenting and cava filter placement were performed in 3 domestic swine. procedures were performed under mri-guidance in an open-bore 1.5-t scanner. the applied 0.035-inch guidewire has a peek core reinforced by f ... | 2009 | 19115070 |
| spontaneous cardiac arrhythmias recorded in three experimentally- and drug-naive laboratory species (canine, primate, swine) during standard pre-study screening. | the purpose of this study was to collect and estimate the general prevalence of spontaneous irregularities in cardiac rhythms in three standard laboratory animal species: beagle dog (n=2450), cynomolgus monkey (n=1563), and domestic swine (n=704) during standard preclinical screening. | 2009 | 19111938 |
| ectopic ventricular rhythms and myocardial infarction in the domestic pig and their response to nialamide, a monoamine oxidase inhibitor. | the development in indian domestic pigs of ectopic ventricular rhythms and a low-frequency tachycardia after the two-stage ligature of the anterior descending branch of the left coronary artery is described. when the ligature was tied 26+/-3 mm from the left auricular margin, the change in rhythm developed after 2 to 2.5 hr, reached a maximum after 6 hr and persisted up to 28 hr. the histopathological character of the resultant acute myocardial infarction is presented. in all, 52 pigs were used. ... | 1962 | 19108169 |
| importance of the porcine adam3 disintegrin domain in sperm-egg interaction. | in the mouse, adam3, a well-characterized testis-specific protein of the a disintegrin and metalloprotease (adam) family, has a crucial role in fertilization by mediating sperm binding to the egg zona pellucida. however, little is known about adam3 in other species, such as domestic pigs. we have identified porcine adam3 and analyzed the protein. rt-pcr and trypsinization of sperm surface proteins revealed that porcine adam3 is expressed at high levels in the testis and on the sperm surface. fur ... | 2009 | 19106482 |
| the house fly (musca domestica) as a potential vector of metazoan parasites caught in a pig-pen in germany. | in the present study a total of 224 specimens of the synanthropic house fly (musca domestica) were caught in a pig-pen of an organic farmer in dormagen (germany). the flies were examined for their potential as a carrier of metazoan parasites. on the exoskeletons and in the intestines of the flies the eggs and/or larvae of four endoparasite nematode species of domestic pigs (ascaris suum, strongyloides ransomi, metastrongylus sp., undetermined strongylida) were isolated. also one ectoparasite spe ... | 2009 | 19081196 |
| soft tissue integration in the neck area of titanium implants--an animal trial. | dental implant materials are required to enable good apposition of bone and soft tissues. they must show sufficient resistance to chemical, physical and biological stress in the oral cavity to achieve good long-term outcomes. a critical issue is the apposition of the soft tissues, as they have provided a quasi-physiological closure of oral cavity. the present experiment was performed to study the peri-implant tissue response to non-submerged (1-stage) implant installation procedures. two differe ... | 2008 | 19075332 |
| evaluation of shape and size changes of bone and remodelled bone substitute after different fixation methods. | suitable tissue fixation is indispensable to histological analysis. this investigation, therefore, sought to evaluate changes of shape and size of bone specimens and remodelled bone substitute material following different fixation methods. mandibular bones of 9 pigs (sus scrofa domesticus) served as specimens. two mandibular premolars were extracted respectively and the extraction alveoli were filled with synthetic bone substitute material. the samples were collected after 70 days. fixation of 6 ... | 2008 | 19075329 |
| trichinella spp. infection in horses of romania: serological and parasitological survey. | herbivorous animals are usually, by virtue of their diet, outside the major transmission cycles of trichinella spp. however, since 1975, the year of the first report of human trichinellosis caused by the consumption of infected horse meat, the domestic horse has appeared as a novel vector of trichinella spp. infection to humans, with 15 outbreaks documented in france and italy. romania, one of the main countries exporting horses into the european union (eu), experienced a dramatic increase of tr ... | 2009 | 19062194 |
| isolation and characterization of intestinal escherichia coli clones from wild boars in germany. | our understanding of the composition of escherichia coli populations in wild boars is very limited. in order to obtain insight into the e. coli microflora of wild boars, we studied e. coli isolates from the jejunums, ileums, and colons of 21 wild boars hunted in five geographic locations in germany. ten isolates per section were subjected to clonal determination using pulsed-field gel electrophoresis. one representative isolate per clone was further investigated for virulence traits, phylogeneti ... | 2009 | 19060173 |
| trichinella pseudospiralis in pig from croatia. | trichinella spiralis and trichinella britovi are species that are frequently found in domestic pigs and various sylvatic animals in croatia. during routine trichinoscopy, non-encapsulated larvae were detected in the muscle tissue of a domestic pig. artificial digestion revealed a larvae burden of 602 muscle larvae per gram of tissue. tissue section analysis confirmed the presence of non-encapsulated larvae. multiplex pcr identified the larvae as t. pseudospiralis. this observation is consistent ... | 2009 | 19054619 |
| inhibition of complement and cd14 attenuates the escherichia coli-induced inflammatory response in porcine whole blood. | the innate immune response is a double-edged sword in systemic inflammation and sepsis. uncontrolled or inappropriate activation can damage and be lethal to the host. several studies have investigated inhibition of downstream mediators, including tumor necrosis factor alpha (tnf-alpha) and interleukin-1beta (il-1beta). emerging evidence indicates that upstream inhibition is a better therapeutic approach for attenuating damaging immune activation. therefore, we investigated inhibition of two cent ... | 2009 | 19047409 |
| desferrioxamine attenuates minor lung injury following surgical acute liver failure. | acute liver failure (alf) can be complicated by lung dysfunction. the aim of this study was to test the hypothesis that inhibition of oxidative stress through iron chelation with desferrioxamine (dfx) attenuates pulmonary injury caused by alf. 14 adult female domestic pigs were subjected to surgical devascularisation of the liver and were randomised to a study group (dfx group, n = 7), which received post-operative intravenous infusion of dfx (14.5 mg x kg(-1) x h(-1) for the first 6 h post-oper ... | 2009 | 19047311 |
| candidate new species of kobuvirus in porcine hosts. | 2008 | 19046542 | |
| african swine fever virus isolate, georgia, 2007. | african swine fever (asf) is widespread in africa but is rarely introduced to other continents. in june 2007, asf was confirmed in the caucasus region of georgia, and it has since spread to neighboring countries. dna fragments amplified from the genome of the isolates from domestic pigs in georgia in 2007 were sequenced and compared with other asf virus (asfv) isolates to establish the genotype of the virus. sequences were obtained from 4 genome regions, including part of the gene b646l that enc ... | 2008 | 19046509 |
| probing of actinobacillus pleuropneumoniae apxiiia toxin-dependent cytotoxicity towards mammalian peripheral blood mononucleated cells. | abstract: | 2008 | 19046441 |
| the birth of a trichinella britovi focus on the mediterranean island of sardinia (italy). | for 60 years, the islands of the mediterranean basin were considered to be trichinella-free. in april 2005, an outbreak of human trichinellosis due to the consumption of infected pork involved 11 persons in the villages of orgosolo and lanusei (nuoro province) on the island of sardinia (italy). we conducted an investigation to identify free-range and backyard pigs and other humans with trichinella infection in the area of the 2005 outbreak. we also tested wild animals from various parts of sardi ... | 2009 | 19041178 |
| pilot study evaluating ureteric physiological changes with a novel 'ribbon stent' design using electromyographic and giant magnetoresistive sensors. | to test a novel 'ribbon stent' (rs) design using an extraluminal bipolar electromyographic (emg) and giant magnetoresistive (gmr) sensor system to characterize ureteric responses. | 2009 | 19040534 |
| species identification of trichinella isolates from china. | two species of trichinella were identified from china by means of pcr amplification of the mitochondrial small subunit ribosomal dna and the expansion segment v region of the ribosomal dna. seven isolates originating from domestic pig and one isolate originating from dog showed identical dna banding pattern to trichinella spiralis, and two isolates from dog showed dna banding pattern identical to trichinella nativa. sequence analysis of the 5s rdna inter-gene spacer region from the ten trichinel ... | 2009 | 19036522 |
| ivabradine induces an increase in ventricular fibrillation threshold during acute myocardial ischemia: an experimental study. | tachycardia often facilitates ischemic ventricular fibrillation (vf). | 2008 | 19034029 |
| occurrence of moniezia expansa (rud, 1810) blanchard, 1891 (cestoda: anoplocephalidae) in domestic pig (sus scrofa domestica linnaeus, 1758) in perú. | the presence of moniezia expansa (rud, 1810) blanchard, 1891, is reported in domestic pig (sus scrofa domestica linnaeus, 1758). four tapeworms were collected and identified as m. expansa. this is the first report of m. expansa collected in a domestic pig in perú. | 2008 | 19028016 |
| diffuse spectral fundus reflectance measured using subretinally placed spectralon. | the diffuse fundus reflectance and the spectral transmittance of the swine sensory retina was measured in vivo using intravitreal illumination. pars plana vitrectomy and intravitreal manipulations were performed on a female american yorkshire domestic swine. light from a scanning monochromator was coupled into a fiber optic intraocular illuminator inserted into the vitreous. a 1.93-mm(2) region of the illuminated fundus was imaged from an oblique illumination angle. multispectral retinal images ... | 2008 | 19021332 |
| pig and guinea pig skin as surrogates for human in vitro penetration studies: a quantitative review. | both human and animal skin in vitro models are used to predict percutaneous penetration in humans. the objective of this review is a quantitative comparison of permeability and lag time measurements between human and animal skin, including an evaluation of the intra and inter species variability. we limit our focus to domestic pig and rodent guinea pig skin as surrogates for human skin, and consider only studies in which both animal and human penetration of a given chemical were measured jointly ... | 2009 | 19013230 |
| transvenous intramyocardial cellular delivery increases retention in comparison to intracoronary delivery in a porcine model of acute myocardial infarction. | clinical trials using intracoronary (ic) delivery of cells have addressed efficacy but the optimal delivery technique is unknown. our study aimed to determine whether transvenous intramyocardial (tvim) approach was advantageous for cellular retention in ami. | 2008 | 19012733 |
| expression, cellular localization and antibody responses of the african swine fever virus genes b602l and k205r. | previously, we identified serological immunodeterminants of african swine fever virus (asfv), including pk205r and pb602l, without homologues in the database. pk205r is expressed as a 33-kd protein from 4 h post-infection onward, initially diffusely distributed throughout cells, and subsequently in viral factories. pk205r was not found in purified virus. both pk205r and pb602l are recognised by hyperimmune antisera from domestic pigs and bushpigs at late time points after infection, suggesting t ... | 2008 | 19011730 |
| comparative study of in vivo lymphatic sealing capability of the porcine thoracic duct using laparoscopic dissection devices. | sealing the lymphatic vessels during abdominal and pelvic surgery is important to prevent the leakage of lymphatic fluid and its resultant sequelae. to our knowledge we compared for the first time the quality of lymphatic sealing by each of 4 commonly used laparoscopic dissection devices. | 2009 | 19010491 |
| enhanced discrimination of african swine fever virus isolates through nucleotide sequencing of the p54, p72, and pb602l (cvr) genes. | complete sequencing of p54-gene from 67 european, american, and west and east african swine fever virus (asfv) isolates revealed that west african and european asfv isolates classified within the predominant genotype i according to partial sequencing of p72 were discriminated into four major sub-types on the basis of their p54 sequences. this highlighted the value of p54 gene sequencing as an additional, intermediate-resolution, molecular epidemiological tool for typing of asfv viruses. we furth ... | 2009 | 19009341 |
| platelets from diabetic pigs exhibit hypersensitivity to thrombin. | responses of platelets from diabetic and diabetic-hyperlipidemic pigs were studied. pigs were made diabetic with single dose of alloxan, which acts by selectively destroying insulin-producing pancreatic beta cells thus inducing type 1 diabetes. pigs were kept for 1 or 12 wk, during which thrombin-induced aggregation was monitored in washed platelets. the platelets showed increased sensitivity to aggregation within 1 wk of induction of diabetes. hyperlipidemia alone for 12 wk did not increase pla ... | 2008 | 19004374 |
| the environmental and public health risks associated with arsenical use in animal feeds. | arsenic exposures contribute significantly to the burden of preventable disease worldwide, specifically related to increased risks of cancer, diabetes, and cardiovascular disease. most exposures are associated with natural contamination of groundwater, which is difficult to mitigate when these sources are used for drinking water. an anthropogenic source of arsenic exposure stems from the widespread use of arsenical drugs in food-animal production in the united states and china, among many countr ... | 2008 | 18991934 |
| [experimental study on a new method for colonoscopic closure of large-bowel perforations with the otsc clip]. | iatrogenic perforation of the colon during interventional endoscopic procedures, e.g., mucosectomy, is a problematic complication, as safe treatment often requires surgical repair. iatrogenic perforation of the colon is indeed a rare complication; however, given the increasing case numbers in interventional endoscopy it is of considerable practical relevance. the closure of perforations can be achieved with conventional endoscopic clips; however, these working channel based clips are often too s ... | 2008 | 18979620 |
| domestic pigs and japanese encephalitis virus infection, australia. | to determine whether relocating domestic pigs, the amplifying host of japanese encephalitis virus (jev), decreased the risk for jev transmission to humans in northern australia, we collected mosquitoes for virus detection. detection of jev in mosquitoes after pig relocation indicates that pig relocation did not eliminate jev risk. | 2008 | 18976557 |
| detection and genetic characterization of porcine circovirus 2 isolates from the first cases of postweaning multisystemic and wasting syndrome in wild boars in greece. | in 2002, postweaning multisystemic wasting syndrome (pmws) was diagnosed in a european female wild boar (sus scrofa), based on the detection of porcine circovirus 2 (pcv2) dna in various organs, including the uterus, and on histopathologic lesions. this is the first detection of pcv2 dna in the uterus of a wild boar. three years later (2005), a wild boar < 6-8 mo of age was found moribund. it presented wasting and dyspnea and finally died. pcv2 dna was detected in tissue samples, and histopathol ... | 2008 | 18957642 |
| isolation and characterization of perv-c env from domestic pig in korea. | clone perv-c (a3) env was isolated from the genomic dna of domestic pig (sus scrofa domesticus) in korea to investigate the molecular properties of perv-c. the nucleic acid homologies between the perv-msl (type c) reference and the perv-c(a3) clone was 99% for env, but a single base pair deletion was found in the transmembrane (tm) region of the env open reading frame. to examine the functional characteristics of truncated perv-c env, we constructed a replication-incompetent retroviral vector by ... | 2008 | 18955828 |
| ten years evidence-based high-tech acupuncture--a short review of peripherally measured effects. | since 1997, the research unit of biomedical engineering in anesthesia and intensive care medicine of graz medical university has been dealing with the demystification of acupuncture and examining, using non-invasive methods, how different stimulation modalities (manual needle acupuncture, laserneedle acupuncture and electro acupuncture) affect peripheral and central functions. laser is also an important instrument for acupuncture. one only needs to mention the treatment of children or of patient ... | 2007 | 18955279 |
| effects of pre-arrest and intra-arrest hypothermia on ventricular fibrillation and resuscitation. | hypothermia has been shown to improve survival and neurological outcomes for ventricular fibrillation (vf) cardiac arrest. the electrophysiological mechanisms of hypothermia are not well-understood, nor are the effects of beginning cooling during the resuscitation. | 2009 | 18952346 |
| purification, molecular cloning, heterologous expression and characterization of pig cyp1a2. | porcine cytochrome p450 (cyp) 1a2 was purified to electrophoretic homogeneity from the hepatic microsomes of beta-naphthoflavone-treated male pigs. in a reconstituted system, this enzyme showed a good catalytic activity towards caffeine, acetanilide, and methoxyresorufin, all known markers of mammalian cyp1a2. using 3'- and 5'-rapid amplification of coding dna (cdna) ends (race), we amplified from the liver rna of control pigs a full-length 1827 bp cdna containing an open reading frame of 1548 b ... | 2008 | 18949657 |
| continuous hemofiltration in pigs with hyperdynamic septic shock affects cardiac repolarization. | sepsis has been defined as the systemic host response to infection with an overwhelming systemic production of both proinflammatory and anti-inflammatory mediators. continuous hemofiltration has been suggested as possible therapeutic option that may remove the inflammatory mediators. however, hemodialysis and hemofiltration were reported to influence cardiac electrophysiologic parameters and to increase the arrhythmogenic risk. we hypothesize that sepsis affects electrophysiologic properties of ... | 2008 | 18936693 |
| optical coherence tomography and intravascular ultrasound imaging of bioabsorbable magnesium stent degradation in porcine coronary arteries. | absorbable metallic stents (ams) composed of magnesium alloy were designed to complete degradation within 90-120 days. among the potential advantages of these stents, when compared to conventional stents, are the elimination of late stent thrombosis, chronic inflammation, and artifacts during noninvasive imaging. | 2008 | 18928950 |
| the trypanocidal effects of dimidium bromide (phenanthridinium 1553) on trypanosoma simiae in domestic pigs. | 1948 | 18891584 | |
| current world status of balantidium coli. | balantidium coli is a cosmopolitan parasitic-opportunistic pathogen that can be found throughout the world. pigs are its reservoir hosts, and humans become infected through direct or indirect contact with pigs. in rural areas and in some developing countries where pig and human fecal matter contaminates the water supply, there is a greater likelihood that balantidiosis may develop in humans. the infection may be subclinical in humans, as it mostly is in pigs, or may develop as a fulminant infect ... | 2008 | 18854484 |
| changes in spatial collagen content and collagen network architecture in porcine articular cartilage during growth and maturation. | the present study was designed to reveal changes in the collagen network architecture and collagen content in cartilage during growth and maturation of pigs. | 2009 | 18849174 |
| spatial distribution of taenia solium porcine cysticercosis within a rural area of mexico. | cysticercosis is caused by taenia solium, a parasitic disease that affects humans and rurally bred pigs in developing countries. the cysticercus may localize in the central nervous system of the human, causing neurocysticercosis, the most severe and frequent form of the disease. there appears to be an association between the prevalence of porcine cysticercosis and domestic pigs that wander freely and have access to human feces. in order to assess whether the risk of cysticercosis infection is cl ... | 2008 | 18846230 |
| endothelin-1 is not predictive of ventricular ectopy or ventricular fibrillation during acute myocardial ischemia. | endothelin(et)-1 (et-1) increases after myocardial infarction and may have effects on myocardial function. et-1 has also been shown to affect the action potential (ap) which may be arrhythmogenic and predispose to ventricular fibrillation (vf). the effects of et-2 and et-3 are uncertain. we hypothesized that the ets increase during acute ischemia and that plasma levels are predictive of ischemically induced vf. thirty-four domestic swine underwent balloon occlusion of the proximal lad coronary a ... | 2008 | 18844577 |
| minimal interruption of cardiopulmonary resuscitation for a single shock as mandated by automated external defibrillations does not compromise outcomes in a porcine model of cardiac arrest and resuscitation. | current automated external defibrillations require interruptions in chest compressions to avoid artifacts during electrocardiographic analyses and to minimize the risk of accidental delivery of an electric shock to the rescuer. the earlier three-shock algorithm, with prolonged interruptions of chest compressions, compromised outcomes and increased severity of postresuscitation myocardial dysfunction. in the present study, we investigated the effect of timing of minimal automated external defibri ... | 2008 | 18824916 |
| detection of brachyspira hyodysenteriae, lawsonia intracellularis and brachyspira pilosicoli in feral pigs. | feral pigs are recognized as being a potential reservoir of pathogenic microorganisms that can infect domestic pigs and other species. the aim of this study was to investigate whether feral pigs in western australia were colonized by the pathogenic enteric bacteria lawsonia intracellularis, brachyspira hyodysenteriae and/or brachyspira pilosicoli. a total of 222 feral pigs from three study-populations were sampled. dna was extracted from faeces or colonic contents and subjected to a previously d ... | 2009 | 18818030 |
| the effect of continuous release of recombinant human epidermal growth factor (rh-egf) in chitosan film on full thickness excisional porcine wounds. | the purpose of this article is to evaluate the effect of continuously released recombinant human epidermal growth factor (rh-egf) in chitosan film in full thickness porcine wounds. a total of 10 domestic pigs (yorkshire species) weighing 18 to 22 kg between the ages of 50 to 60 days were used. the wounds were divided into 3 groups and treated selectively with rh-egf in chitosan film (egf 20 ug/wound/d), chitosan film without rh-egf, or remained as the control group. one hundred percent healing t ... | 2008 | 18812721 |
| restenosis is not associated with stent length in a pig model of coronary stent implantation. | the aim of this study was to determine if stent length is by itself a risk factor for intimal proliferation and restenosis. long lesions represent an independent risk factor for restenosis after coronary stent implantation. a longer stented segment might result in a higher probability of restenosis. | 2008 | 18810722 |
| the use of composite meshes in laparoscopic repair of abdominal wall hernias: are there differences in biocompatibily?: experimental results obtained in a laparoscopic porcine model. | in recent years, laparoscopic repair of abdominal wall hernias has become increasingly established in routine clinical practice thanks to the myriad advantages it confers. apart from the risk of intestinal damage following adhesiolysis, to date no information is available on the best way of preventing the formation of new adhesions in the vicinity of the implanted meshes. numerous experimental investigations, mainly conducted on an open small-animal model, have demonstrated the advantages of coa ... | 2009 | 18806942 |
| finite element representation of bone substitute remodelling in the jaw bone. | the finite element (fe) method was originally developed on a physical basis for the computation of structure-mechanical problems. meanwhile, it has been widely applied to medical issues. this study sought a suitable method to build a fe model for remodelling processes in osseous defects supplemented with bone substitute material. for this purpose, the second right premolars were extracted from four pig mandibles (sus scrofa domesticus) and the extraction alveoli were provided with synthetic bone ... | 2008 | 18803527 |
| intravenous tezosentan and vardenafil attenuate acute hypoxic pulmonary hypertension. | excessive hypoxic pulmonary hypertension imposes right ventricular strain by increasing afterload that may lead to right heart failure and death. increased phosphodiesterase activity, as well as increased levels of endothelin-1, has been discussed as molecular mechanisms. we investigated the hemodynamic and intrapulmonary effects of the intravenous dual endothelin a and b receptor blocker tezosentan, and of the phosphodiesterase-5 (pde-5) antagonist vardenafil in a pig model of acute normobaric ... | 2008 | 18800959 |
| isolation and cloning of two variant papillomaviruses from domestic pigs: sus scrofa papillomaviruses type 1 variants a and b. | the healthy skin of two female domestic pigs (sus scrofa domestica) was sampled with cotton-tipped swabs. total genomic dna was extracted from the samples and subjected to pcr with degenerate papillomavirus (pv)-specific primers. similarity searches performed with blastn showed that partial e1 and l1 sequences of two novel pvs were amplified. subsequently, the complete genomes of these sus scrofa papillomaviruses (sspvs) were amplified by long-template pcr, cloned and sequenced using a transposo ... | 2008 | 18796716 |
| sleep-induced hypotension precipitates severe myocardial ischemia. | epidemiologic studies have shown a high frequency of major cardiac events at night in patients with coronary artery disease. this has been attributed to the sympathetic surges accompanying rapid eye movement (rem) sleep; the role of non-rem sleep, which comprises 80% of total sleep duration, has been largely neglected. accordingly, we evaluated the effect of non-rem sleep on contractile function in a region of the left ventricular wall supplied by a flow-limiting coronary stenosis. | 2008 | 18788646 |
| identification and sequencing of remnant messenger rnas found in domestic swine (sus scrofa) fresh ejaculated spermatozoa. | the existence of specific messenger rna remnants contained within freshly ejaculated spermatozoa was described in several species. those investigations, using high-throughput techniques to screen the population of transcripts in ejaculated spermatozoa, were limited to the probes which mostly derived from nucleic acids of testicular tissues of either human or mice. the objective of this study was to investigate mrna remnants from ejaculated spermatozoa of the domestic swine (sus scrofa), a valuab ... | 2009 | 18786788 |
| the proinflammatory cytokine response following resuscitation in the swine model depends on the method of ventricular fibrillation induction. | a systemic inflammatory response has been reported following resuscitation from cardiac arrest. the purpose of this study was to compare the magnitude of the tumor necrosis factor-alpha (tnf-alpha) response in two different swine models of ventricular fibrillation (vf) arrest. | 2008 | 18785945 |
| vocal mother-offspring communication in guinea pigs: females adjust maternal responsiveness to litter size. | abstract: | 2008 | 18783602 |
| in vivo evaluation of anodic tio2 nanotubes: an experimental study in the pig. | because of their ability to mimic the dimensions of constituent components of natural bone and the possibility to serve as a gene and drug-delivery carrier, nanotubes seem to be a promising coating for medical implants. aim of this study was to investigate the effects of a tio(2) nanotube structured surface on periimplant bone formation in vivo when compared with an untreated standard titanium surface. twenty-five titanium implants covered with an ordered tio(2) nanotube layer with an individual ... | 2009 | 18780361 |
| natural orifice translumenal endoscopic surgery (notes) renal cryoablation in a porcine model. | to present our laboratory experience with natural orifice translumenal endoscopic surgery (notes) renal cryoablation. | 2008 | 18778358 |
| development of two trichoplusia ni larvae-derived elisas for the detection of antibodies against replicase and capsid proteins of porcine circovirus type 2 in domestic pigs. | the main aim of the present study was to describe new methods for the identification of antibodies against the pcv2 capsid (cap) and replicase (rep) proteins in pig sera. specifically, two new indirect enzyme-linked immunosorbent assays (elisa) were developed based on recombinant pcv2 cap (rcap) and rep/rep' (rrep) proteins expressed in baculovirus and produced in trichoplusia ni insect larvae. both assays were validated by testing serum samples in a longitudinal study of 107 animals with differ ... | 2008 | 18773923 |
| development of a swine model of secondary liver tumor from a genetically induced swine fibroblast cell line. | metastatic disease is the most common liver tumor. although alternative therapies have been developed for non-surgical candidates, those therapies lacked ideal testing prior to clinical application because of a paucity of large animal models. the purpose of the present study was to develop a model for secondary liver tumor in a large animal. | 2008 | 18773055 |
| small intestinal submucosa as a bioscaffold for tissue regeneration in defects of the colonic wall. | small intestinal submucosa (sis) has proved considerable regenerative capacity for repair of bowel wall defects at different locations. this study assesses the effectiveness of sis in the repair of defects at a gastrointestinal location with strong bacterial contamination. | 2009 | 18766420 |
| manganese-enhanced mri of acute cardiac ischemia and chronic infarction in pig hearts: kinetic analysis of enhancement development. | to assess infarction development in pig hearts, mn-enhanced and gd-enhanced mri were used. in domestic pigs (25-35 kg, n = 37), the first and second diagonal branches of the left anterior descending coronary artery were ligated to induce acute ischemia and infarction (ischemia+reperfusion) or chronic infarction of increasing duration (3- 28 days). ex vivo experiments were performed on hearts perfused in the langendorff mode with a 50:50 mixture of blood and krebs-henseleit buffer using a spin-ec ... | 2009 | 18756440 |
| [frequency of chromosomes carrying endogenous retroviruses in the populations of domestic pig and wild boar]. | statistical analysis of the frequency of chromosomes carrying three types (a, b, and c) of porcine endogenous retroviruses (perv) was based on molecular-genetic testing of populations of domestic pigs and wild boars. domestic pigs were shown to have higher frequency of perv and haplotypes containing two and three types of perv than wild boars. | 2008 | 18727389 |
| epicardial pulmonary vein isolation: a long-term histologic and imaging animal study comparing cryothermy versus radiofrequency. | simplifications of the cox-maze procedure to treat atrial fibrillation (af) include epicardial pulmonary vein (pv) isolation using various sources to create lines of conduction block. the creation of transmural lesions has been a concern. the heat-sink effect caused by blood flow has limited the effectiveness of unipolar radiofrequency and linear application of cryothermy, which should be abolished when clamp devices are used for pv isolation. the efficacy and safety of epicardial beating-heart ... | 2008 | 18721573 |
| evaluation of unmeshed and 1:1 meshed alloderm bolsters for stapled rectal anastomoses in a porcine model. | the major morbidity of colorectal anastomoses is leaks. the concept of staple-line reinforcement is a growing area of interest. in this study, we evaluated the feasibility and effect of utilizing alloderm to bolster end-to-end stapled rectal anastomoses in a porcine model. | 2008 | 18721018 |
| notes: a review of the technical problems encountered and their solutions. | natural orifice translumenal endoscopic surgery (notes) is currently investigated and developed worldwide. in the past few years, multiple groups have confronted this challenge. many technical problems are encountered in this technique due to the currently available tools for this approach. some of the unique technical problems in notes include: blindly performed primary incisions; uncontrolled pneumoperitoneal pressure; no support for the endoscope in the abdominal cavity; inadequate vision; in ... | 2008 | 18721009 |
| human dispersal of trichinella spiralis in domesticated pigs. | to investigate the human impact on the evolutionary ecology of animal pathogens, we compared genetic diversity of severe foodborne parasites contracted by eating infected pork or wild game. in particular, we characterized trichinella spp. from twenty-eight countries and four continents by genotyping nine microsatellite loci and sequencing one-fifth of the mitochondrial genome. all specimens of trichinella spiralis, a swine parasite that can infect many species of wildlife, were remarkably unifor ... | 2008 | 18718558 |
| [molecular identification of heparin from pigs by allele-specific pcr (as-pcr) and amplification refractory mutation system (arms)]. | the aim of this study is to develop a convenient and effective method for the identification of heparin from pigs (include sus scrofa domestica brisson and sus scrofa riukiuanus). based on sequences of d-loop region of pigs and the other animals, two pairs of highly specific primers were designed for distinguishing heparin of pigs from other animals. the primers were employed to amplify d-loop region of dna templates extracted from pig and seven other animal species that amounted to 49 samples. ... | 2008 | 18717344 |
| hosts and habitats of trichinella spiralis and trichinella britovi in europe. | trichinella spiralis and trichinella britovi are the two most common species of trichinella circulating in europe. based on data provided to the international trichinella reference centre over the past 20 years (data referring to 540 isolates of t. spiralis and 776 isolates of t. britovi), we describe the host species and habitat characteristics for these two pathogens in europe. a geographical information system was constructed using administrative boundaries, a corine land cover (clc) map, and ... | 2009 | 18708065 |
| endoscopic ultrasound-guided ethanol injection in the pancreas in a porcine model: a preliminary study. | despite aggressive multimodal treatments, survival rates for patients with pancreatic cancer remain disappointing. local progression is problematic, and minimally invasive procedures allowing locoregional control are needed. in this study, we attempted endoscopic ultrasound (eus)-guided injection of ethanol into the pancreas. | 2008 | 18702683 |
| influence of ventilation strategies on survival in severe controlled hemorrhagic shock. | to investigate the effect of different ventilation settings on hemodynamic stability in severe controlled hemorrhagic shock. | 2008 | 18679111 |
| does selective intubation increase ablation zone size during pulmonary cryoablation? | to determine the effect of selective intubation on ablation zone size during pulmonary cryoablation. | 2008 | 18662888 |
| insect succession and decomposition patterns on shaded and sunlit carrion in saskatchewan in three different seasons. | a study was conducted on decomposition and insect succession in the prairie ecozone of saskatchewan in the year 2000. eighteen domestic pig carcasses (42-79 kg) were employed as human models for applications to future homicide investigations in this region. two major variables were considered including the effect of season and habitat (sun versus shade). research was conducted over 25 weeks, spanning three seasons: spring, summer and fall. ambient temperature, internal carcass temperature, fauni ... | 2008 | 18662603 |
| guidelines for the identification and development of sampling methods and design of suitable protocols for monitoring of trichinella infection in indicator species. | summary: according to the european community regulation no. 2075/2005, a risk-based program should be implemented in those areas where wildlife and pig holdings applying for trichinella-free status coexist, or for region where the risk of trichinella in domestic swine is officially recognised as negligible. trichinella nematode species are primarily parasites of wildlife which can transmit the infection to pigs intended for human consumption, acting as reservoir of the parasite. since not all ma ... | 2008 | 18660570 |
| comparison of selected skin decontaminant products and regimens against vx in domestic swine. | an anesthetized domestic swine model was used to compare the efficacy and cross-contamination potential of selected skin decontaminant products and regimens against the chemical warfare agent, vx. animals topically exposed to 2x, 3x or 5x ld(50) vx showed typical signs of organophosphate nerve agent poisoning, including miosis, salivation, mastication, dysrhythmias, and respiratory distress prior to death. animals were exposed to 5x ld(50) vx and then decontaminated 45 min later with the reactiv ... | 2008 | 18650258 |
| the effect of pest control on the incidence of trichinosis in virovitica-podravina county, croatia. | the aim of the study was to assess the role of pest control as a preventive measure in the control of trichinosis. the investigation was designed as a retrospective cohort study in the virovitica-podravina county. the incidence of trichinosis was determined according to the presence or absence of exposure to protective pest control measures. differences in the rate of trichinosis infection were determined by calculating relative risk (rr), i.e., the ratio of absolute risk in the two groups. in t ... | 2008 | 18644676 |
| detection of trichinella spiralis, t. britovi and t. pseudospiralis in muscle tissue with real-time pcr. | infections caused by trichinella species occur throughout the world in many wild and domestic animals resulting in trichinellosis in men. in europe, domestic pigs are predominantly infected by three trichinella species: t. spiralis, t. britovi and t. pseudospiralis. present methods for detection of trichinella spp. (compressorium method, artificial digestion) do not always sufficiently recognize trichinella larvae and these techniques are labor-intensive, time consuming and do not differentiate ... | 2008 | 18639594 |
| expression of mitochondrial transcription factor a (tfam) during porcine gametogenesis and preimplantation embryo development. | mitochondrial transcription factor a (tfam) is responsible for stability, maintenance, and transcriptional control of mitochondrial dna (mtdna). we have studied the expression and distribution of tfam in the gametes and preimplantation embryos of the domestic pig (sus scrofa). we hypothesized that tfam is not present in the boar sperm mitochondria to reduce the possibility of paternal mtdna propagation in the progeny. in contrast, we anticipated that tfam gene is expressed in a developmental sta ... | 2008 | 18636550 |
| distinct subtypes of urinary bladder epithelial cells with inducible and non-inducible cytochrome p450 1a1. | cultured primary porcine urinary bladder epithelial cells (pubec) represent an adequate and easy to handle in vitro system for studies of urothelial toxicity. pubec maintain in vivo-like metabolic activities and physiological functions. they express inducible cytochrome p4501a isoenzymes, which are of particular relevance, since they contribute to activation of bladder carcinogens. a possible drawback of pubec is their isolation from common domestic pigs that do not represent an inbred strain. i ... | 2009 | 18636242 |
| the differences between venous air embolism and fat embolism in routine intraoperative monitoring methods, transesophageal echocardiography, and fatal volume in pigs. | venous air embolism (vae) or fat embolism (fe) may occur in similar clinical settings such as after multiple injuries or total hip replacement. we designed this study to observe the differences between vae and fe in routine intraoperative monitoring methods, transesophageal echocardiography (tee), and fatal volume in pigs. | 2008 | 18636024 |
| traditional zootherapeutic studies in india: a review. | the present study aims to review the zootherapeutic practices of the different ethnic communities of india. this work is also an attempt to present a list of animals' use for medicinal purposes by different communities of india. data were gathered from 15 published research papers of various authors on zootherapeutic studies in india from 2000 to 2007. approximately 109 animals and their 270 uses are reported in traditional medicine in different parts of india. of these, the highest numbers of a ... | 2008 | 18634551 |
| serological evidence for hepatitis e virus infection in laboratory monkeys and pigs in animal facilities in japan. | in laboratory animal facilities, monkeys and pigs are used for animal experiments, but the details of hepatitis e virus (hev) infection in these animals are unknown. the risk of infection from laboratory animals to humans has become a concern; therefore, much attention should be paid to the handling of these animals during their care and use, including surgical procedures performed on infected animals. in this connection, serum samples collected from 916 monkeys and 77 pigs kept in 23 animal fac ... | 2008 | 18633159 |
| domestic pigs have low susceptibility to h5n1 highly pathogenic avian influenza viruses. | genetic reassortment of h5n1 highly pathogenic avian influenza viruses (hpai) with currently circulating human influenza a strains is one possibility that could lead to efficient human-to-human transmissibility. domestic pigs which are susceptible to infection with both human and avian influenza a viruses are one of the natural hosts where such reassortment events could occur. virological, histological and serological features of h5n1 virus infection in pigs were characterized in this study. two ... | 2008 | 18617994 |
| patterns of crystallin distribution in porcine eye lenses. | to measure the protein distribution patterns in single young porcine lenses. | 2008 | 18615203 |
| detection and size differentiation of simulated tooth root defects using flat-panel volume computerized tomography (fpvct). | our aim was to evaluate the capacity of flat-panel volume computerized tomography (fpvct) to enable the observer to detect and differentiate 3 different sizes of simulated tooth root defects in radiographs. | 2009 | 18602316 |
| molecular identification and prevalence of isospora sp. in pigs in western australia using a pcr-rflp assay. | little is known about the prevalence of isospora in domestic pigs in western australia. a total of 289 pig faecal samples were collected from pre- and post-weaned pigs and sows from 1 indoor and 3 outdoor piggeries located in the south-west region of western australia. faecal samples were screened using a pcr-rflp assay based on the its-1 rdna locus. an overall prevalence of 10.4% (30/289) was identified. isospora was detected in 16.3% (20/123) of pre-weaned animals and 6.4% (10/156) of post-wea ... | 2008 | 18601925 |
| acalculous and clostridial cholecystitis in a pig. | a 21-month-old domestic hanford pig (sus scrofa domestica) in a 1-year study for experimental myocardial infarction was euthanized at the end of the study. one week earlier, the animal had symptoms and elevated clinical chemistry results suggestive of hepatobiliary disease, which resolved after medical therapy. at necropsy, the gallbladder was markedly enlarged, discolored, and had a thickened wall. within the gallbladder, there was abundant friable green-brown material. a culture of the gallbla ... | 2008 | 18599865 |
| development of real-time polymerase chain reaction assays for rapid detection and differentiation of wild-type pseudorabies and gene-deleted vaccine viruses. | the successful eradication of pseudorabies in u.s. domestic swine was accomplished through the use of glycoprotein e (ge) deleted modified live virus vaccines and an accompanying ge differential enzyme-linked immunosorbent assay (elisa). yet, pseudorabies virus (prv) was established in feral swine in the united states, becoming a potential reservoir of prv for infection of domestic swine and other native wildlife. a critical need for the current prv surveillance program in the united states is t ... | 2008 | 18599848 |
| carbon dioxide contrast agent for ct arteriography: results in a porcine model. | to test the feasibility of carbon dioxide (co(2))-enhanced computed tomographic (ct)-arteriography in an animal model. | 2008 | 18589320 |
| laparoscopic repair of inferior vena caval injury using a chitosan-based hemostatic dressing. | vena caval injury is a rare but serious complication of laparoscopic surgery, and often requires conversion to an open procedure. the current study investigated whether a vena caval injury could be repaired with a chitosan dressing laparoscopically. | 2009 | 18585679 |
| renal injury and the application of polysaccharide hemospheres: a laparoscopic experimental model. | microporous polysaccharide hemospheres (mph) are hemostatic beads engineered from purified plant starch. mph accelerates the natural clotting cascade by concentrating clotting factors and proteins on their surface while absorbing aqueous and low molecular weight components from blood. the purpose of this study was to determine the efficacy of mph in achieving hemostasis in the setting of laparoscopic renal injury. | 2008 | 18578666 |
| dynamic chemical characteristics of soil solution after pig manure application: a column study. | when manures from intensive livestock operations are applied to agricultural or vegetable fields at a high rate, large amounts of salts and metals will be introduced into soils. using a column leaching experiment, this study assessed the leaching potential of the downward movement of cu and zn as well as some salt ions after an intensive farm pig manure at rates of 0%, 5% and 10% (w/w) were applied to the top 20 cm of two different textured soils (g soil -sandy loam soil; h soil-silty clay loam ... | 2008 | 18576224 |
| post-resuscitation hemodynamics and relationship to the duration of ventricular fibrillation. | we have observed consistent hemodynamic patterns after restoration of spontaneous circulation (rosc) after ventricular fibrillation (vf) cardiac arrest. we sought to characterize the time-course of these patterns, and to determine whether these differed based on duration of the vf insult. | 2008 | 18573588 |