Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
|---|
| the spread of klebsiella pneumoniae carbapenemases: a tale of strains, plasmids, and transposons. | 2009 | 19886796 | |
| interspecies spread of klebsiella pneumoniae carbapenemase gene in a single patient. | klebsiella pneumoniae carbapenemase (kpc)-producing k. pneumoniae, escherichia coli, and serratia marcescens were sequentially identified in a patient who underwent small bowel transplantation. molecular typing and plasmid analysis suggested that the kpc gene was acquired by e. coli, most likely from k. pneumoniae, and was subsequently transferred to s. marcescens. | 2009 | 19886795 |
| novel low-temperature-active phytase from erwinia carotovora var.carotovota accc 10276. | a phytase with high activity at low temperatures has great potential for feed applications, especially in aquaculture. therefore, this study used a degenerate pcr and tail pcr to clone a phytase gene from erwinia carotovora var. carotovota, the cause of soft rot of vegetables in the ground or during cold storage. the full-length 2.5-kb fragment included an open reading frame of 1,302 bp and encoded a putative phytase of 45.3 kda with a 50% amino acid identity to the klebsiella pneumoniae phytase ... | 2009 | 19884763 |
| isolation and characterization of two members of the siderophore-microcin family, microcins m and h47. | in this paper we provide the first biochemical evidence of the existence of a family of structure-related antimicrobial peptides, the siderophore-microcins, in the enterobacteriaceae family. we isolated and characterized two novel siderophore-microcins, mccm and mcch47, previously characterized through genetic studies. mccm and mcch47 were expressed from several escherichia coli strains containing the microcin gene clusters. the spectra of their bactericidal activities were found to be restricte ... | 2010 | 19884380 |
| molecular and biochemical characterization of the natural chromosome-encoded class a beta-lactamase from pseudomonas luteola. | pseudomonas luteola (formerly classified as cdc group ve-1 and named chryseomonas luteola) is an unusual pathogen implicated in rare but serious infections in humans. a novel beta-lactamase gene, bla(lut-1), was cloned from the whole-cell dna of the p. luteola clinical isolate lam, which had a weak narrow-spectrum beta-lactam-resistant phenotype, and expressed in escherichia coli. this gene encoded lut-1, a 296-amino-acid ambler class a beta-lactamase with a pi of 6 and a theoretical molecular m ... | 2010 | 19884377 |
| uranium(vi) reduction and removal by high performing purified anaerobic cultures from mine soil. | biological uranium reduction was investigated using bacteria isolated from a uranium mine in limpopo, south africa. background uranium concentration in soil from the mine was determined to be 168 mgkg(-1) much higher than the typical background uranium concentration in natural soils (0.30-11.7 mgkg(-1)). therefore it was expected that the bacteria isolated from the site were resistant to u(vi) toxicity. preliminary studies using a non-purified consortium from the mine soil showed that u(vi) [ura ... | 2010 | 19883933 |
| [analysis on the sensitivity to beta-lactam antibiotics of respiratory-infectious isolates on the second survey on the sensitivity of isolates conducted by the japanese society of chemotherapy in 2007--concerning the aspect of pk/pd break points]. | sensitivity to beta-lactam antibiotics of isolates clinically obtained from respiratory infection sites in adults on the second survey on sensitivity of isolates conducted by the japanese society of chemotherapy in 2007 was investigated according to the classification of the "guideline for treatment for adult nosocomial pneumonia in 2008". among the primary antibacterial drugs for mild (a) and moderate (b) nosocomial pneumonia in adults, beta-lactam antibiotics; ceftriaxone (ctrx), sulbactam/amp ... | 2009 | 19882981 |
| [antibacterial activity of quinolones against various clinically isolated strains and evaluation of efficacy based on the pharmacokinetics/pharmacodynamics theory]. | we compared the antimicrobial activities of oral quinolones, ciprofloxacin (cpfx), gatifloxacin (gflx), garenoxacin (grnx), levofloxacin (lvfx), moxifloxacin (mflx), norfloxacin (nflx), prulifloxacin (pufx), and tosufloxacin (tflx) using streptococcus pneumoniae, haemophilus influenzae, streptococcus agalactiae, streptococcus pyogenes, extended spectrum beta-lactamase(esbl) producing klebsiella pneumoniae, and methicillin-susceptible staphylococcus aureus (mssa) isolated from clinical materials. ... | 2009 | 19882980 |
| [a case of empyema due to capnocytophaga sp. and actinomyces israelii]. | a 54-year-old man was admitted to our hospital for investigation of cough, sputum production, and fever of 1 month's duration. his diabetes mellitus was poorly controlled, and his hemoglobin hba1c value was elevated at 10.9%. chest x-ray film and computed tomography scan showed bilateral but predominantly right-sided pleural effusion. aspiration of the pleural fluid from the right-side showed frank pus, and empyema was diagnosed. capnocytophaga sp. and actinomyces israelii were isolated in the p ... | 2009 | 19882914 |
| isolation of bacteria causing secondary bacterial infection in the lesions of cutaneous leishmaniasis. | cutaneous leishmaniasis (cl) is a parasitic disease characterized by single or multiple ulcerations. secondary bacterial infection is one of the complications of the disease that can increase the tissue destruction and the resulting scar. | 2008 | 19882011 |
| colistin and polymyxin b: a re-emergence. | one of the greatest achievements of modern medicine is the development of antibiotics against life-threatening infections, but the emergence of multidrug-resistant (mdr) gram negative bacteria has drastically narrowed down the therapeutic options against them. this limitation has led clinicians to reappraise the clinical application of polymyxins, an old class of cationic, cyclic polypeptide antibiotics. polymyxins are active against selected gram-negative bacteria, including the acinetobacter s ... | 2009 | 19881183 |
| cerebritis: an unusual complication of klebsiella pneumoniae. | cerebritis is part of a continuum of brain infection and is difficult to diagnose. cerebritis caused by klebsiella in immunocompetent adults without predisposing factors such as neurosurgery or penetrating brain injury has not been reported before. we report a case of klebsiella cerebritis in an adult patient with a proven extracranial focus of infection. we suggest considering cerebritis as a differential diagnosis for altered level of consciousness in patients of severe sepsis, even if an extr ... | 2009 | 19881180 |
| assessment of microbiological quality of sachet-packaged drinking water in western nigeria and its public health significance. | to assess the microbiological quality of sachet-packaged drinking water in western nigeria and its impact on public health. | 2009 | 19880150 |
| synthesis, stereochemistry and antimicrobial studies of novel oxime ethers of aza/diazabicycles. | two series of bicyclic oxime ethers viz, 2,4-diaryl-3-azabicyclo[3.3.1]nonan-9-one o-benzyloximes 13-24 and 2,4,6,8-tetraaryl-3,7-diazabicyclo[3.3.1]nonan-9-one o-benzyloximes 31-36 were synthesized and stereochemistry was established by their spectral (1d and 2d nmr) and crystal studies. synthesized oxime ethers were screened for their in vitro antimicrobial activity against a set of pathogenic bacteria (pseudomonas aeruginosa, staphylococcus aureus, salmonella typhi, escherichia coli and klebs ... | 2009 | 19879756 |
| chromium (vi) biotransformation by beta- and gamma-proteobacteria from natural polluted environments: a combined biological and chemical treatment for industrial wastes. | the high solubility of cr(vi) in aqueous systems, together with carcinogenic and mutagenic effects on living organisms, make industrial effluents receive specific treatments for cr(vi) elimination. biotreatments, based on biotransformation of cr(vi) to cr(iii) which is immobilized as cr(oh)(3), are the most effective methods for the removal of cr(vi) concentrations below 2mm. the aim of our study is the application of pure or mixed bacterial cultures for cr(vi) biotransformation followed by chem ... | 2010 | 19879691 |
| use of automated repetitive-sequence-based pcr for rapid laboratory confirmation of nosocomial outbreaks. | rapid and reliable diagnosis of genetic relatedness of clinical isolates in microbiologic laboratory is essential in case of nosocomial outbreak investigation. most molecular techniques used to type microorganisms are technically demanding and time consuming. currently repetitive-sequence-based pcr (rep-pcr) technique has been adapted to an automated format on the diversilab system (biomérieux, marcy l'etoile, france). aim of this study was to compare the performance of the diversilab system to ... | 2010 | 19879293 |
| evaluation of new chromogenic substrates for the detection of coliforms. | to evaluate a new range of chromogenic substrates for the detection of beta-galactosidase activity in coliforms and to compare their performance in agar media and broths. | 2010 | 19878523 |
| cross-reaction between proteins of larrea divaricata cav. (jarilla) and proteins of gram-negative bacteria. | larrea divaricata is an abundant plant of northwest of argentina used to treat different pathologies. we aimed to characterize the immunogenicity of proteins from a partially purified crude aqueous extract (jpce) of jarilla. we evaluated the cross reaction between jpce and whole cell-bacterial proteins (w-cbp) of escherichia coli, pseudomonas aeruginosa, proteus vulgaris, and klebsiella pneumoniae using a mouse anti-jpce serum. protein profiles of jpce and w-cbp were analyzed. for jpce, 18 bands ... | 2009 | 19874237 |
| risk factors and clinical impact of klebsiella pneumoniae carbapenemase-producing k. pneumoniae. | klebsiella pneumoniae carbapenemase (kpc)-producing k. pneumoniae is an emerging pathogen with serious clinical and infection control implications. to our knowledge, no study has specifically examined risk factors for kpc-producing k. pneumoniae or its impact on mortality. | 2009 | 19860564 |
| [bacteria isolated from surgical infections and their susceptibility to antimicrobial agents--special reference to bacteria isolated between april 2007 and march 2008]. | bacteria isolated from infections in abdominal surgery during the period from april 2007 to march 2008 were investigated in a multicenter study in japan, and the following results were obtained. in this series, 707 strains including 24 strains of candida spp. were isolated from 181 (79.0%) of 229 patients with surgical infections. three hundred and ninety-five strains were isolated from primary infections, and 288 strains were isolated from postoperative infections. from primary infections, anae ... | 2009 | 19860320 |
| why hypothetical protein kpn00728 of klebsiella pneumoniae should be classified as chain c of succinate dehydrogenase? | twenty percent of genes that encode for hypothetical proteins from klebsiella pneumoniae mgh78578 were identified, leading to kpn00728 and kpn00729 after bioinformatics analysis. both open reading frames showed high sequence homology to succinate dehydrogenase chain c (sdhc) and d (sdhd) from escherichia coli. recently, kpn00729 was assigned as sdhd. kpn00728 thus remains of particular interest as no annotated genes from the complete genome sequence encode for sdhc. we discovered kpn00728 has a ... | 2009 | 19859792 |
| ventilator-associated nosocomial pneumonia in intensive care units in malaysia. | the outcome indicator of nosocomial infection (ni) in the intensive care unit (icu) is used to benchmark the quality of patient care in malaysia. we conducted a three-year prospective study on the incidences of ventilator-associated pneumonia (vap), risk factors, and patterns of the microorganisms isolated in three icus. | 2009 | 19858572 |
| the in-vitro antimicrobial activity of some medicinal plants against beta-lactam-resistant bacteria. | in effort to identify novel bacterial agents, this study was initiated to evaluate the antimicrobial properties of 17 crude extracts from 12 medicinal plants against beta-lactam-resistant bacteria. | 2009 | 19858568 |
| klebsiella pneumoniae acrab efflux pump contributes to antimicrobial resistance and virulence. | respiratory infections caused by klebsiella pneumoniae are characterized by high rates of mortality and morbidity. management of these infections is often difficult, due to the high frequency of strains that are resistant to multiple antimicrobial agents. multidrug efflux pumps play a major role as a mechanism of antimicrobial resistance in gram-negative pathogens. in the present study, we investigated the role of the k. pneumoniae acrrab operon in antimicrobial resistance and virulence by using ... | 2010 | 19858254 |
| acute appendicitis presenting with klebsiella pneumoniae septicemia due to bacterial translocation. | bacterial translocation (bt) is defined as the passage of viable bacteria from the gastrointestinal tract, across the intestinal wall, to the mesenteric lymph nodes or other extranodal sites and bloodstream. it has been shown in both animal and human studies and has been implicated as a source of sepsis in susceptible patients. herein, a rare case of acute appendicitis in a nonimmunocompromised patient who presented with manifestations of klebsiella pneumoniae septicemia, is described. transloca ... | 2009 | 19857441 |
| [aminoglycoside resistance of enterobacteria isolated from urinary infections in surgical departments]. | the aim of the study was to determine the aminoglycosides resistance of enterobacteriaceae strains isolated from urocultures. identification of the germs was performed by the api system (biomerieux) and susceptibility tests was performed by disk-diffusion test (clsi standards) and with api strips. for detecting the resistance to aminoglycosides we used gentamicin, tobramycin, netilmicin and amikacin. from 2500 urine samples we isolated 673 microbial strains, from which 531 were enterobacteriacea ... | 2008 | 19856848 |
| dominance of ctx-m-2 and ctx-m-56 among extended-spectrum beta-lactamases produced by klebsiella pneumoniae and escherichia coli isolated in hospitals in paraguay. | 2009 | 19854861 | |
| [kpc carbapenemases: what is at stake in clinical microbiology?]. | emergence and dissemination of carbapenem resistance in the world represent a significant threat for management of hospital-acquired infections. from the early 2000s, enterobacteriaceae that produce klebsiella pneumoniae carbapenemases (kpc) have initially been reported from the usa and now worldwide, becoming the most important carbapenemase. these kpc producing-bacteria are mostly involved in nosocomial and systemic infections. they are mostly enterobacteriaceae and more rarely pseudomonas aer ... | 2010 | 19854586 |
| development of a method based on surface enhanced laser desorption and ionization time of flight mass spectrometry for rapid identification of klebsiella pneumoniae. | a method based on surface enhanced laser desorption and ionization time of flight mass spectrometry (seldi-tof ms) was developed for the rapid identification of klebsiella pneumoniae by directly applying bacterial colonies without further protein extraction. a total of 40 k. pneumoniae and 114 other related microorganisms isolated clinically were analyzed by seldi-tof ms. an identification model for k. pneumoniae was established by artificial neural networks (anns) with classification accuracy o ... | 2009 | 19851739 |
| prediction of bacterial proteins carrying a nuclear localization signal and nuclear targeting of hsdm from klebsiella pneumoniae. | nuclear targeting of bacterial proteins is an emerging pathogenic mechanism whereby bacterial proteins can interact with nuclear molecules and alter the physiology of host cells. the fully sequenced bacterial genome can predict proteins that target the nuclei of host cells based on the presence of nuclear localization signal (nls). in the present study, we predicted bacterial proteins with the nls sequences from klebsiella pneumoniae by bioinformatic analysis, and 13 proteins were identified as ... | 2009 | 19851738 |
| nitroreductase ii involved in 2,4,6-trinitrotoluene degradation: purification and characterization from klebsiella sp. cl. | three 2,4,6-trinitrotoluene (tnt) nitroreductases from klebsiella sp. ci have different reduction capabilities that can degrade tnt by simultaneous utilization of two initial reduction pathways. of these, nitroreductase ii was purified to homogeneity by sequential chromatographies. nitroreductase ii is an oxygen-insensitive enzyme and reduces both tnt and nitroblue tetrazolium. the n-terminal amino acid sequence of the enzyme did not show any sequence similarity with those of other nitroreductas ... | 2009 | 19851725 |
| rapid detection of esbl-producing gram-negative bacteria isolated from blood: a reasonable and reliable tool for middle and low resource countries. | delay in appropriate treatment in patients with bacteraemia can increase morbidity, mortality, and health expenditures. we compared the rapid direct test (rdt) designed to detect esbl-producing gram-negative bacteria (gnb) directly from positive blood cultures bottles, with two conventional esbl detection tests: screening and confirmatory disk diffusion assay (sc-dda) and an mic screening and esbl e-test (mic/et). | 2009 | 19848308 |
| both trif- and myd88-dependent signaling contribute to host defense against pulmonary klebsiella infection. | klebsiella pneumoniae causes extensive lung damage. tlr signaling involves adaptors trif and myd88. however, the relative contribution of trif and myd88 signaling in host defense against pulmonary k. pneumoniae infection has not been elucidated. therefore, we investigated the role of trif and myd88 in k. pneumoniae pneumonia. trif(-/-) mice infected with k. pneumoniae showed impaired survival and reduced bacterial clearance, neutrophil influx, histopathologic evidence of inflammation, and tnf-al ... | 2009 | 19846873 |
| characterization of corrosive bacterial consortia isolated from petroleum-product-transporting pipelines. | microbiologically influenced corrosion is a problem commonly encountered in facilities in the oil and gas industries. the present study describes bacterial enumeration and identification in diesel and naphtha pipelines located in the northwest and southwest region in india, using traditional cultivation technique and 16s rdna gene sequencing. phylogenetic analysis of 16s rrna sequences of the isolates was carried out, and the samples obtained from the diesel and naphtha-transporting pipelines sh ... | 2010 | 19844704 |
| fixed-dose combination of cefepime plus amikacin (potentox) inhibits pneumonia infection. | pneumonia is a severe infection that causes high morbidity and mortality rate worldwide. it is caused by klebsiella pneumoniae, which generally causes upper respiratory tract infection. in case of such type of infection, levels of oxidant and antioxidant become imbalanced, which may contribute to lung injury. the present study was planned to evaluate the status of oxidant and antioxidant enzyme activities in plasma and lung tissue of pneumonia-infected rats model. animals were randomly distribut ... | 2009 | 19842849 |
| attributable hospital cost and length of stay associated with health care-associated infections caused by antibiotic-resistant gram-negative bacteria. | determination of the attributable hospital cost and length of stay (los) are of critical importance for patients, providers, and payers who must make rational and informed decisions about patient care and the allocation of resources. the objective of the present study was to determine the additional total hospital cost and los attributable to health care-associated infections (hais) caused by antibiotic-resistant, gram-negative (gn) pathogens. a single-center, retrospective, observational compar ... | 2010 | 19841152 |
| roles of capsule and lipopolysaccharide o antigen in interactions of human monocyte-derived dendritic cells and klebsiella pneumoniae. | in humans, klebsiella pneumoniae is a saprophytic bacterium of the nasopharyngeal and intestinal mucosae that is also frequently responsible for severe nosocomial infections. two major factors of virulence, capsular polysaccharide (cps) and lipopolysaccharide (lps) o antigen, are involved in mucosal colonization and the development of infections. these bacterial surface structures are likely to play major roles in interactions with the mucosal immune system, which are orchestrated by a network o ... | 2010 | 19841082 |
| antibacterial, antifungal, and antiviral activities of some flavonoids. | antibacterial and antifungal activities of six plant-derived flavonoids representing two different structural groups were evaluated against standard strains of escherichia coli, pseudomonas aeruginosa, proteus mirabilis, klebsiella pneumoniae, acinetobacter baumannii, staphylococcus aureus, enterococcus faecalis, bacillus subtilis and their drug-resistant isolates, as well as fungi (candida albicans, c. krusei) using the microdilution broth method. herpes simplex virus type-1 and parainfluenza-3 ... | 2010 | 19840899 |
| emphysematous pyelonephritis: a case report series of four patients with review of literature. | emphysematous pyelonephritis (epn) is an acute necrotizing infection with gas presence in the kidney, perinephric space, and/or urinary collecting system that carries a bad prognosis. some clinical conditions predispose to this entity, such as diabetes mellitus, urinary tract obstruction, and immune-incompetence. immediate resuscitation, broad-spectrum antibiotics, percutaneous and surgical drainage, and emergent and delayed nephrectomy are therapeutic options that should be applied in a timely ... | 2009 | 19839858 |
| biodegradation of thiocyanate using co-culture of klebsiella pneumoniae and ralstonia sp. | thiocyanate-degrading microbial co-culture was isolated from thiocyanate-contaminated site and tested for thiocyanate degradation potential and thiocyanate-toxicity tolerance and identified as klebsiella pneumoniae and ralstonia sp. by 16s rdna sequencing. the co-culture was able to degrade thiocyanate with degradation rate of 500 mg l(-1)d(-1) at 2,500 mg l(-1) thiocyanate concentration at ph 6.0 and 37 degrees c following thiocyanate hydrolase pathway. the haldane kinetic model elucidates the ... | 2010 | 19838695 |
| ammonium and phosphate limitation in 1,3-propanediol production by klebsiella pneumoniae. | excretion of 1,3-propanediol (1,3-pd) by k. pneumoniae was compared in ammonium- and phosphate-limited chemostat cultures running with an excess of glycerol. 59 and 43% catabolic flux were directed to 1,3-pd in ammonia-limited cultures and phosphate-limited cultures at dilution rate of 0.1 h(-1), respectively. ammonia-limited fed-batch cultures produced 61 g 1,3-pd l(-1) and a total of 15 g l(-1) organic acid in 36 h. however, phosphate-limited fed-batch cultures excreted 61 g lactate l(-1) and ... | 2010 | 19838630 |
| risk factors and outcome in extended spectrum beta-lactamase producing escherichia coli and klebsiella pneumoniae bacteremia. | 2009 | 19838454 | |
| maternal risk factors in early neonatal sepsis at a tertiary care teaching hospital. | to study the maternal risk factors in blood culture proven cases of early neonatal sepsis, and study the isolates and the sensitivity of these isolates. | 2009 | 19838438 |
| [epidemiology of esbl-positive enterobacteriaceae in mantova hospital (italy)]. | in a retrospective study concerning the epidemiology of extended-spectrum beta-lactamase (esbl) positive enterobacteriaceae during 2007-2008 in the wards of the carlo poma hospital in mantova, mercurio surveillance software was used to detect alert microorganisms. our objective was to link the epidemiological data with the type of patient and ward, and to assess the risk factors for such infections in particular nosocomial environments. the study enabled the change in the relative epidemiologica ... | 2009 | 19838088 |
| in vitro activity of tigecycline against 2423 clinical isolates and comparison of the available interpretation breakpoints. | mics to tigecycline and 12 antimicrobials were performed by microdilution method, against 2423 nonduplicate pathogens recently isolated in 17 greek hospitals. the food and drug administration (fda) and european committee on antimicrobial susceptibility testing (eucast) criteria were used comparatively for interpretation of tigecycline mics. tigecycline exhibited potent in vitro activity against the majority of the isolates tested. (mic(90) values of 0.5, 1, 2, 0.125, 1, 0.25, 0.125, and 1 mg/l w ... | 2010 | 19836184 |
| [expression of acetohydroxyacid synthase isozyme genes ilvbn, ilvgm, ilvih and their resistance to ahas-inhibitor herbicides]. | acetohydroxyacid synthase (ahas) catalyses the first reaction in the pathway for synthesis of the branched-chain amino acids. ahas is the target for sulfonylurea, imidazolinone and other ahas-inhibitor herbicides. herbicides-resistant ahas genes have potential application in plant transgenetic engineering and development of new generation herbicide. the ahas isozyme genes ilvbn, ilvgm and ilvih were cloned from metsulfuron-methyl resistant strain klebsiella sp. hr11 and metsulfuron-methyl sensit ... | 2009 | 19835141 |
| adding to yersinia enterocolitica gene pool diversity: two cryptic plasmids from a biotype 1a isolate. | we report the nucleotide sequence of two novel cryptic plasmids (4357 and 14 662 base pairs) carried by a yersinia enterocolitica biotype 1a strain isolated from pork. as distinguished from most biotype 1a strains, this isolate, designated 07-04449, exhibited adherence to eukaryotic cells. the smaller plasmid pye4449-1 carries five attributable open reading frames (orfs) encoding the first ccda/ccdb-like antitoxin/toxin system described for a yersinia plasmid, a repa-like replication initiation ... | 2009 | 19834620 |
| mucosal lipocalin 2 has pro-inflammatory and iron-sequestering effects in response to bacterial enterobactin. | nasal colonization by both gram-positive and gram-negative pathogens induces expression of the innate immune protein lipocalin 2 (lcn2). lcn2 binds and sequesters the iron-scavenging siderophore enterobactin (ent), preventing bacterial iron acquisition. in addition, lcn2 bound to ent induces release of il-8 from cultured respiratory cells. as a countermeasure, pathogens of the enterobacteriaceae family such as klebsiella pneumoniae produce additional siderophores such as yersiniabactin (ybt) and ... | 2009 | 19834550 |
| endogenous endophthalmitis caused by citrobacter koseri. | endogenous endophthalmitis occurs when organisms are hematogenously disseminated in to the eye from a distant focus of infection. the most common isolated organisms that cause endogenous endophthalmitis are klebsiella pneumoniae and escherichia coli. previous reports on endophthalmitis caused by citrobacter species are limited. we present the first case of endogenous endophthalmitis caused by citrobacter koseri bacteremia and renal abscesses. | 2009 | 19834321 |
| summary trends for the meropenem yearly susceptibility test information collection program: a 10-year experience in the united states (1999-2008). | the meropenem yearly susceptibility test information collection (mystic) program was a global, longitudinal antimicrobial resistance surveillance network of more than 100 medical centers worldwide monitoring the susceptibility of meropenem and selected other broad-spectrum comparator agents. in 1999, and from 2000 through 2008, a total of 10 or 15 united states (usa) medical centers each forwarded 200 nonduplicate clinical isolates from serious infections to a central processing laboratory. over ... | 2009 | 19833471 |
| emergence of esbl-producing escherichia coli and klebsiella pneumoniae isolates during the years 2000 and 2004 in helsinki, finland. | abstract the molecular epidemiology of 33 e. coli and 81 k. pneumoniae esbl-producing health-care associated and community-acquired isolates collected in the helsinki district during 2000-2004 was investigated. clonality studies, antimicrobial susceptibility and genotyping of the isolates were performed. newly emerging ctx-m-producing e. coli and bla(shv-12)-producing k. pneumoniae were detected. clonal clusters of both species persisted throughout the study period. | 2009 | 19832719 |
| breast milk causing neonatal sepsis and death. | breast milk can occasionally transmit serious viral and bacterial infections to preterm infants. we present three cases of late-onset neonatal sepsis, including one that resulted in death, occurring in preterm infants. the likely source of the microorganisms in all three cases was expressed breast milk. | 2010 | 19832716 |
| liver abscess caused by klebsiella pneumoniae: two case reports. | the present case reports highlight the peculiar aspect of klebsiella pneumoniae liver abscess, an emerging disease in united states and western countries. | 2009 | 19829875 |
| characteristics of pyogenic liver abscess patients with and without diabetes mellitus. | pyogenic liver abscess (pla) is relatively common in patients with diabetes mellitus (dm), but it is unclear whether there are differences between patients with and without dm. we conducted a study to identify the possible differences and factors that affect fatality. | 2010 | 19826410 |
| pyogenic liver abscess as the first manifestation of hepatobiliary malignancy. | pyogenic liver abscess (pla) is commonly seen in patients in the far east. similarly, hepatobiliary neoplasms are also common. pla as the initial manifestation of hepatobiliary neoplasms is extremely rare. | 2009 | 19822502 |
| first isolations of kpc-2-carrying st258 klebsiella pneumoniae strains in finland, june and august 2009. | the first two klebsiella pneumoniae carbapenemase-producing (kpc) type 2 strains carrying st258 were detected in finland in june and early august 2009. they were found colonising two patients transferred from the mediterranean; one patient referred from a hospital in greece where isolates were first found in 2007 and another from italy where the first isolates have been described only very recently. | 2009 | 19822122 |
| synergic degradation of phenanthrene by consortia of newly isolated bacterial strains. | three different bacteria capable of degrading phenanthrene were isolated from sludge of a pulp wastewater treatment plant and identified as acinetobacter baumannii, klebsiella oxytoca, and stenotrophomonas maltophilia. phenanthrene degradation efficiencies by different combinations (consortia) of these bacteria were investigated and their population dynamics during phenanthrene degradation were monitored using capillary electrophoresis-based single-strand conformation polymorphism (ce-sscp). whe ... | 2009 | 19818817 |
| chemical composition and antimicrobial activity of the extracts of kefe cumin (laser trilobum l.) fruits from different regions. | structural properties (using gas chromatographic analyses: gas chromatography and gas chromatography-mass spectrometry) of some compounds (pure chemicals, essential oils, extracts, etc.) and systematic investigation of antimicrobial activities (with agar dilution and agar diffusion disc methods) were determined in the fruits of kefe cumin (laser trilobum l.) obtained from different regions (germany, india, and turkey). the main components were established as limonene (41.03-72.24%) and perillald ... | 2009 | 19817640 |
| necrotising fasciitis of the extremity. | necrotising fasciitis is a rare, life-threatening infection where there is necrosis of fascia, subcutaneous tissues and skin. three adult patients presented with this condition affecting the extremities and all had predisposing medical factors. each one complained of severe pain that seemed disproportionate to the skin affected. they underwent prompt surgical debridement and received antibiotic treatment and supportive therapy. these cases highlight the increasing incidence and differences in pr ... | 2010 | 19815478 |
| the transmission of nosocomial pathogens in an intensive care unit: a space-time clustering and structural equation modelling approach. | we investigated the incidence of cases of nosocomial pathogens and risk factors in an intensive treatment unit ward to determine if the number of cases is dependent on location of patients and the colonization/infection history of the ward. a clustering approach method was developed to investigate the patterns of spread of cases through time for five microorganisms [methicillin-resistant staphylococcus aureus (mrsa), acinetobacter spp., klebsiella spp., candida spp., and pseudomonas aeruginosa] ... | 2010 | 19814850 |
| effects of chelators (deferoxamine, deferiprone and deferasirox) on the growth of klebsiella pneumoniae and aeromonas hydrophila isolated from transfusion-dependent thalassemia patients. | infections are among the leading causes of death for thalassemia major patients. the known predisposing factors of infection include prior splenectomy, iron overload and use of iron chelator such as deferoxamine (dfo). while encapsulated organisms frequently found in splenectomized patients were readily controlled by prophylactic vaccination and vigilant antibiotic treatment, ferrophilic organisms such as yersinia and klebsiella remain common pathogens in thalassemic patients. yersinia infection ... | 2009 | 19814682 |
| health-care associated infections rates, length of stay, and bacterial resistance in an intensive care unit of morocco: findings of the international nosocomial infection control consortium (inicc). | most studies related to healthcare-associated infection (hai) were conducted in the developed countries. we sought to determine healthcare-associated infection rates, microbiological profile, bacterial resistance, length of stay (los), and extra mortality in one icu of a hospital member of the international infection control consortium (inicc) in morocco. | 2009 | 19811636 |
| multidrug-resistant gram-negative bacteria in postoperative infections. | gram-negative bacteria are responsible in an important way in hospital-associated infections and their reported resistance to multiple antimicrobials is a matter of grave concern. in this study, gram-negative bacteria isolated from clinical samples of postoperative infected patients were identified and their antibiotic susceptibility patterns determined. the prevalence of multidrug-resistant gram-negative bacteria was 9.45% and the highest prevalence was seen in gi surgery department. escherichi ... | 2009 | 19810380 |
| brain abscess in children. | to find out the clinical presentation, radiological characteristics, various underlying predisposing conditions and causative organisms of brain abscess in children in our setup. | 2005 | 19810297 |
| behaviour of ceftazidime towards beta-lactamases. | from escherichia coli, enterobacter cloacae, proteus morganii and pseudomonas aeruginosa, but the geometric mean of the inhibition constant ki used to measure this interaction was 120 and almost 700 times higher with ceftazidime than with cefotaxime and cefuroxime, respectively. two other beta-lactamases isolated from pr. vulgaris and klebsiella oxytoca also showed little or no interaction with ceftazidime. a complementary microbiological technique, the "double-disc" technique, indicated that ce ... | 1981 | 19810176 |
| in-vitro activity of ceftazidime, a beta-lactamase stable cephalosporin. | the in-vitro activity and beta-lactamase stability of ceftazidime were evaluated against 700 gram-positive and gram-negative bacteria. ceftazidime was less active than penicillins or older cephalosporins against staphylococcus spp. and streptococcus spp., and it did not inhibit streptococcusfaecalis. however, ceftazidime was as active as moxalactam and cefoperazone against escherichia coli, klebsiella and proteus mirabilis with mics less than 0.2 mg/l. ceftazidime also inhibited enterobacter, ci ... | 1981 | 19810175 |
| investigation of klebsiella pneumoniae isolates producing shv-12 and shv-11 beta-lactamases in korean hospitals. | of 143 clinical isolates of klebsiella pneumoniae collected from korean non-tertiary hospitals, 24 (16.8%) showed an extended-spectrum beta-lactamase-positive phenotype. pcr and sequence analysis revealed the presence of tem-116 (n=13), ctx-m-3 (n=5), ctx-m-14 (n=2), ctx-m-15 (n=3), and shv-12 (n=16). each of the 24 isolates encoded more than one beta-lactamase, and seven isolates (29%) harbored two different shv-type beta-lactamase genes (blashv-11 and blashv-12) bounded by insertion sequence i ... | 2009 | 19809267 |
| comparative pharmacodynamics of intermittent and prolonged infusions of piperacillin/tazobactam using monte carlo simulations and steady-state pharmacokinetic data from hospitalized patients. | prolonging the infusion of a beta-lactam antibiotic enhances the time in which unbound drug concentrations remain above the minimum inhibitory concentration (ft>mic). | 2009 | 19809009 |
| prevalence of antimicrobial-resistant bacteria isolated from older versus younger hospitalized adults: results of a two-centre study. | to compare the proportion of antimicrobial-resistant strains among bacterial isolates from younger and older hospital patients and to quantify changes in the proportion of antimicrobial-resistant strains in both groups over time. | 2009 | 19808237 |
| restricting ciprofloxacin-induced resistant variant formation in biofilm of klebsiella pneumoniae b5055 by complementary bacteriophage treatment. | the in vitro efficacy of lytic bacteriophage as a therapeutic agent against klebsiella pneumoniae biofilm, alone or in combination with ciprofloxacin, was studied. the pathogenic potential of the resistant variants formed during the treatment was evaluated. | 2009 | 19808232 |
| regional trends in multidrug-resistant infections in german intensive care units: a real-time model for epidemiological monitoring and analysis. | a new surveillance module for multidrug-resistant (mdr) bacteria was added to the intensive care component of the german nosocomial infection surveillance system. participating intensive care units (icus) report data on all patients colonised or infected with meticillin-resistant staphylococcus aureus (mrsa), vancomycin-resistant enterococci (vre) and extended-spectrum beta-lactamase-producing escherichia coli and klebsiella pneumoniae (esbl-ec/kp). to determine the regional distribution of mrsa ... | 2009 | 19804919 |
| between community and hospital: healthcare-associated gram-negative bacteremia among hospitalized patients. | healthcare-associated, community-acquired bacteremia is a subcategory of community-acquired bacteremia distinguished by recent exposure of the patient to the healthcare system before hospital admission. our objective was to apply this category to a prospective cohort of hospitalized patients with gram-negative bacteremia to determine differences in the epidemiological characteristics, treatment, and outcome of community-acquired bacteremia; healthcare-associated, community-acquired bacteremia; a ... | 2009 | 19803723 |
| use of ceftazidime in severe gram-negative infections--a preliminary study. | ceftazidime was used to treat ten patients with serious gram-negative bacillary infections. seven patients had bronchopulmonary infections and three had urinary tract infections. in addition three patients were bacteraemic. causative agents were: pseudomonas aeruginosa 4, escherichia coli 2, proteus species 2, and klebsiella pneumoniae 2. doses ranged between 2 and 6 g/day. nine out of ten patients responded favourably to ceftazidime (cure or improvement). colonization with ceftazidime-resistant ... | 1981 | 19803007 |
| the in-vivo antibacterial activity of ceftazidime (gr 20263)--a comparison with other new beta-lactam antibiotics and gentamicin. | ceftazidime was compared with cefotaxime, ceftizoxime, cefmenoxime, cefotiam, cefoperazone, moxalactam, piperacillin, carbenicillin, mezlocillin, cefsulodin and the aminoglycoside antibiotic gentamicin in a series of mouse protection tests. ceftazidime, together with the other cephalosporin antibiotics and moxalactam were equally effective against infections caused by staphylococcus aureus with ed50 values ranging from 3.5 to 25 mg/kg. gentamicin was the most active antibiotic with ed50 values o ... | 1981 | 19802994 |
| antibacterial activity of ceftazidime (gr 20263) against routine hospital isolates and highly resistant strains of enterobacteriaceae and pseudomonas aeruginosa. | ceftazidime was found to be highly active against routine hospital isolates of strains of enterobacteriaceae such as escherichia coli, klebsiella aerogenes, enterobacter cloacae and proteus mirabilis, with the mean mics varying between 0.11 and 0.75 mg/l. it had marked activity against pseudomonas aeruginosa with a mean mic of 1.8 mg/l which was comparable to tobramycin (11 mg/l) and superior to other aminoglycosides, penicillins and cefotaxime. although ceftazidime was considerably more active ... | 1981 | 19802975 |
| in-vitro comparison of ceftazidime and nine other antimicrobial agents against hospital strains of gram-negative bacteria. | the agar dilution in-vitro susceptibility of 370 isolates of aerobic gram-negative bacteria isolated at ben taub general hospital in houston, texas were determined for five new and five currently available agents. ceftazidime, moxalactam, cefotaxime, ceftizoxime and cefoperazone, all of which are new beta-lactam compounds, were compared with two penicillins, piperacillin, ticarcillin, and three aminoglycosides, gentamicin, tobramycin and amikacin. ceftazidime inhibited 100% of pseudomonas strain ... | 1981 | 19802969 |
| the in-vitro activity of ceftazidime compared with that of other cephalosporins. | the in-vitro activity of ceftazidime was compared with the activities of cefoperazone, cefotaxime, cefsulodin, cefuroxime, cephalothin and cefatriaxon against 331 clinical bacterial isolates. against escherichia coli, salmonella, enterobacter, proteus mirabilis and indole-positive proteus ceftazidime, with mic90 of < or = 0.25 mg/l, was more active than cephalothin, cefoperazone and cefuroxime but less active than cefotaxime and ceftriaxone klebsiella pneumoniae, serratia, acinetobacter and citr ... | 1981 | 19802968 |
| ceftazidime: in-vitro antibacterial activity and susceptibility to beta-lactamases compared with that of cefotaxime, moxalactam and other beta-lactam antibiotics. | the in-vitro antibacterial activity of ceftazidime was assessed against recent clinical isolates of common bacteria and also against reference strains that produced known beta-lactamases. the compound was active, though less so than cephaloridine against staphylococci and streptococci with mics mostly 0.12-2 mg/l for streptococci and 8 mg/l for staphylococci, but enterococci (mics > or =64 mg/l) and methicillin-resistant staphylococci (mics 16-32 mg/l) were resistant. penicillin-resistant pneumo ... | 1981 | 19802967 |
| the susceptibility of nosocomial pathogens to ceftazidime. | the activities in vitro of ceftazidime and of cefuroxime have been compared against 201 strains of bacteria which had been isolated either from outbreaks of nosocomial infection or were typical of strains causing such outbreaks. ceftazidime was found to be about 1000 times more active against pseudomonas spp. and proteus vulgaris, and between 10 and 100 times more active against klebsiella pneumoniae, enterobacter spp., citrobacter freundii, serratia marcescens, proteus rettgeri, proteus morgani ... | 1981 | 19802966 |
| the potential role of mobile phones in the spread of bacterial infections. | mobile phones are indispensable accessories both professionally and socially but they are frequently used in environments of high bacteria presence. this study determined the potential role of mobile phones in the dissemination of diseases. | 2009 | 19801807 |
| comparison of beta-lactamase genes in clinical and food bacterial isolates in india. | the present study aimed to determine the occurrence of human disease-causing enteric bacteria on raw vegetables, fruits, meats, and milk products sold in indian markets. the study further aimed to analyze antibiotic resistance rates and the presence of blactx-m, blatem, blashv, and blaampc. | 2009 | 19801801 |
| synthesis and in vitro microbiological evaluation of novel 4-aryl-5-isopropoxycarbonyl-6-methyl-3,4-dihydropyrimidinones. | seven 4-aryl-5-isopropoxycarbonyl-6-methyl-3,4-dihydropyrimidin-2(1h)-ones 4a-g and 4-phenyl-5-isopropoxycarbonyl-6-methyl-3,4-dihydropyrimidin-2(1h)-thione 4h have been synthesized by a one-pot cyclocondensation of aldehydes, isopropyl acetoacetate and urea/thiourea in ethanol by using strontium chloride hexahydrate as the catalyst. all the compounds were screened for their antibacterial activity against staphylococcus aureus, escherichia coli, klebsiella pneumoniae, pseudomonas aeruginosa and ... | 2010 | 19800716 |
| [extension of antimicrobial drugs resistance: two clinical isolates of klebsiella pneumoniae with cephalosporinase]. | 2010 | 19800186 | |
| kinetic and theoretical study of the chalcones as inhibitors of beta-lactamase enzyme. | staphyloccoccus aureus, escherichia coli, pseudomonas aeruginosa, klebsiella pneumoniae, acinetobacter baumannii, enterobacter cloacae and more bacteria have shown resistance to antibiotics in colombia, therefore, resistance to antibiotics is a problem that is on increase in colombia. the resistance mechanism to penicillin antibiotics in these bacteria is the expression of beta-lactamase enzyme. in order to use the penicillin antibiotics which are still effective against them, we had evaluated 1 ... | 2009 | 19799548 |
| [isolation and characteristics of triphenyltin-biosorption and biodegradation strain]. | the biosorption and biodegradation of triphenyltin (tpht) from aqueous solutions by isolated strains were investigated through microbial separation and characteristic studies. the results illuminated that klebsiella pneumoniae was an effective strain for the biosorption and removal of tpht. 70% to 97.9% of tpht with initial concentration of 3 mg x l(-1) could be absorbed within 2 h, and 26.4% to 54.6% of this tpht was biodegraded within 5 d using 0.3 g x l(-1) to 3.0 g x l(-1) biomass of k. pneu ... | 2009 | 19799316 |
| relapsing deep neck infection may indicate a coexisting esophagus cancer. | neck abscess and deep neck infections are common diseases. primary head and neck cancers may present initially with neck abscesses or deep neck infections. this presentation leads to delay of the diagnosis of underlying cancer. head and neck cancers which present with deep neck infection initially have rarely been described. we report a case with relapsing deep neck infection who was diagnosed as proximal esophagus squamous cell carcinoma thereafter. | 2009 | 19796009 |
| [effect of efflux pump inhibitor 1-(1-naphthylmethyl)-piperazine to mic values of ciprofloxacin in ciprofloxacin resistant gram-negative bacteria]. | effective efflux pump systems play a crucial role in the development of multiple antimicrobial resistance in bacteria. in this study, the effects of an efflux pump inhibitor 1-(1-naphthylmethyl)-piperazine on ciprofloxacin (cip) minimum inhibitory concentration (mic) values in gram-negative bacteria including escherichia coli, pseudomonas aeruginosa and klebsiella pneumoniae were investigated. nineteen cip-resistant p. aeruginosa, 37 extended spectrum beta-lactamase (esbl) positive e. coli and 1 ... | 2009 | 19795621 |
| epididymal abscess in renal transplant: uncommon presentation of klebsiella septicemia. | we present a renal allograft recipient 16 months posttransplant with an unusual infectious complication. this gentleman was antihepatitis c virus pretransplant, had a live unrelated transplant, and was taking cyclosporine, mycophenolate mofetil, and prednisolone. he developed diabetes and left scrotal abscess 3 months posttransplant and underwent left orchiectomy. he developed acute right epididymitis progressing to epididymal abscess, septicemia, and acute chronic graft dysfunction. blood cultu ... | 2010 | 19795181 |
| microbial utilization of the industrial wastewater pollutants 2-ethylhexylthioglycolic acid and iso-octylthioglycolic acid by aerobic gram-negative bacteria. | industrial wastewater from the production of sulfur containing esters and the resulting products of this synthesis, 2-ethylhexylthioglycolic acid (ehtg) and iso-octylthioglycolic acid (iotg), were deployed in this study to enrich novel bacterial strains, since no wastewater and ehtg or iotg degrading microorganisms were hitherto described or available. in addition, nothing is known about the biodegradation of these thiochemicals. the effect of this specific wastewater on the growth behaviour of ... | 2010 | 19789984 |
| risk factors and outcomes for bloodstream infections with extended-spectrum beta -lactamase-producing klebsiella pneumoniae ; findings of the nosocomial surveillance system in hungary. | risk factors for and outcomes of bloodstream infections (bsis) caused by esbl-producing and by esbl-non-producing klebsiella pneumoniae were compared in a four-year multicenter study in hungary. one hundred esbl-positive and one hundred esbl-negative patients were included as cases and controls. investigated risk factors were related to demographics, comorbid conditions, treatments, invasive procedures, surgery prior bacteremia, presence of additional nosocomial infections and preceding hospital ... | 2009 | 19789140 |
| [resistance to fluoroquinolone among klebsiella spp strains producing extended-spectrum betalactamases isolated from urine]. | the aim of the study was to assess the frequency of resistance to fluoroquinolones in extended-spectrum beta-lactamase (esbls) klebsiella spp isolated from urines of consulting and hospitalized patients in rabat specialities hospital. a retrospective survey was made over 3 years (2006-2008). two hundred ant fifty three patients presented with confirmed urinary tractus infection (uti). klebsiella spp was the etiologic agent in 28% (72/253) of reported uti. among them, 86% of klebsiella pneumoniae ... | 2009 | 19789127 |
| intraoperative blood salvage and leukocyte depletion during liver transplantation with bacterial contamination. | bacterial contamination is considered to be a contraindication for intraoperative blood salvage (ibs) during olt. the aims of this study were to evaluate the efficiency of the autotransfusion device with an additional leukocyte depletion filter (ldf) for eliminating bacterial contaminations, and its clinical outcomes in terms of post-operative infections during olt. | 2010 | 19788448 |
| oxyr, a lysr-type regulator involved in klebsiella pneumoniae mucosal and abiotic colonization. | colonization of the gastrointestinal tract is the first event in klebsiella pneumoniae nosocomial infections, followed by colonization of the bladder or respiratory tract or entry into the bloodstream. to survive in the host, bacteria must harbor specific traits and overcome multiple stresses. oxyr is a conserved bacterial transcription factor with a key role both in the upregulation of defense mechanisms against oxidative stress and in pathogenesis by enhancing biofilm formation, fimbrial expre ... | 2009 | 19786563 |
| revisiting the importance of virulence determinant maga and its surrounding genes in klebsiella pneumoniae causing pyogenic liver abscesses: exact role in serotype k1 capsule formation. | mucoviscosity-associated gene a (maga) is proposed to play a decisive role in the pathogenesis of liver abscesses due to klebsiella pneumoniae. although some investigators consider maga to be a putative o-antigen ligase, it is also reportedly associated with the k1 antigen. | 2010 | 19785524 |
| carriage rate of carbapenem-resistant klebsiella pneumoniae in hospitalised patients during a national outbreak. | during a national outbreak of carbapenem-resistant klebsiella pneumoniae (crkp) in israel, we conducted a point prevalence survey to determine the extent of asymptomatic carriage. subsequently, a retrospective case-control study was done, comparing carriers of crkp with non-carriers, in order to detect risk factors for carriage. oral, perianal and rectal swabs were obtained from all hospitalised eligible and consenting patients. selective media for carbapenem-resistant gram-negative bacteria wer ... | 2010 | 19783067 |
| intestinal microbial ecology in premature infants assessed with non-culture-based techniques. | to use high throughput techniques to analyze intestinal microbial ecology in premature neonates, who are highly susceptible to perturbations of the luminal environment associated with necrotizing enterocolitis (nec) and late-onset sepsis. | 2010 | 19783002 |
| bacteriology of external ocular infections in aba, south eastern nigeria. | bacteria are microbial agents that frequently cause infections of the eye and possible loss of vision. | 2009 | 19780761 |
| repeated bacteremia with subsequent septic arthritis caused by klebsiella pneumoniae capsular serotype k57 in a patient with diabetes. | 2009 | 19780664 | |
| association of bacterial colonization at the time of presentation to a combat support hospital in a combat zone with subsequent 30-day colonization or infection. | u.s. casualties have developed multidrug-resistant (mdr) bacterial infections. a surveillance project to evaluate u.s. military patients for the presence of mdr pathogens from wounding through the first 30 days of care in the military healthcare system (mhs) was performed. u.s. military patients admitted to a single combat support hospital in iraq during june-july of 2007 had screening swabs obtained for the detection of mdr bacteria and a subsequent retrospective electronic medical records revi ... | 2009 | 19780364 |
| [etiology of surgical site infections at the orthopaedic trauma units]. | the aim of the study was to analyze the epidemiological and microbiological analysis of surgical site infections in the orthopedic wards. | 2009 | 19780335 |