Publications

effects of acute and chronic inhalation of hashish, marijuana, and delta 9-tetrahydrocannabinol on brain electrical activity in man: evidence for tissue tolerance.	an eeg profile for cannabis preparations equated for delta 9-thc activity has been defined in occasional cannabis users in new york and in long-term, high-dose hashish users in athens. the eeg effects of enhanced alpha activity, decreased beta activity, and decreased mean frequency are dose dependent, both in intensity and in duration. the behavioral measures, particularly self-ratings of euphoria ("high" or "mastura") and heart rate, are also dose dependent and interrelated with the eeg measure ...	1976	1071390
central nervous system infections in new york state. etiologic and epidemiologic observations, 1974.		1975	1059007
the content of 90sr in the bone tissue of the population of the soviet union. (1959-1971) (the basic laws of its accumulation and distribution).	on the basis of the results of long-term observations, general laws have been identified determining the dynamics of 90sr concentration in the bone tissue of the population of the ussr in 1959-71, the peculiarities of 90sr accumulation in different age groups and the connection and dependences between the intake and the contect of the isotope in human organism. it has been found that maximum 90sr concentration occur in children born in the year when nuclear tests were carried out. the type of di ...	1976	1036498
legal rights of the voluntary patient.		1976	1036109
new york hospitals get new guidelines for patient research.		1976	1028322
treating the total patient.		1976	1027673
the informal community caregiver: a link between the health care system and local residents.	a group of "informal" caregivers, local people to whom residents turn for information and advice, was identified in the east harlem community and enlisted in a two-month study. results suggest that formal human services agencies and their intended clientele would benefit by increased efforts on the part of these institutions to locate and work with community caregivers.	1976	998745
dynamics of contraceptive failures.	the purpose of this study was to explore the vicissitudes of contraceptive efforts and practice, and human behavior contributing to contraceptive failure. a consecutive sample of 481 women, who visited various gynecological out-patient clinics of a new york city municipal hospital between august 1974 and august 1975, served as the study population. there were 181 women with planned pregnancies and 300 women with unplanned pregnancies. the data were gathered in personal interviews. by comparison ...	1976	994065
employing ex-addicts: determinants of support and opposition.	in 1973 public hearings of the temporary (n.y.) state commission to evaluate the drug laws concluded with a report which documented pervasive controversy and discrimination in employing rehabilitated or ex-addicts. to analyze local attitudes to this issue, the present study targeted the audience of a recent symposium "employment of the ex-addict", held in westchester county, new york, october, 1973. ss (n = 83) completed a questionnaire to assess the nature and extent of proponent views, degree ...	1976	992921
a method for surveillance of influenza epidemics.		1976	970519
man-made radionuclides and sedimentation in the hudson river estuary.	recently deposited fine-grained sediments in the hudson river estuary contain radionuclides from global fallout produced by atmospheric bomb tests as well as from low-level releases of a local nuclear reactor. accumulation rates of these nuclides are dependent on rates of sediment deposition and vary with location in the estuary by more than two orders of magnitude. within the hudson estuary, new york harbor is currently the zone of most rapid deposition of sediments containing radionuclides, so ...	1976	959844
a multivariate analysis of the relationship between parental age and birth order and the human secondary sex ratio.		1976	956205
the computer as an unbiased medical investigator. experience on an active surgical service.	an adaptable on-line computer system for entry, retrieval, and analysis of medical discharge summaries has been developed and applied in the trauma service of a busy city hospital. each summary occupied 5 to 10 minutes of the physician's time and compared favorably in cost to the standard dictated summary. while the average dictated summary contained 15 +/- 7 relevant facts, the machine-generated summaries were found to have 53 +/- 20 relevant facts. the summaries are well organized, easily comp ...	1976	952350
proceedings: the relation of air pollution to mortality.		1976	932839
changing patterns in the incidence of rocky mountain spotted fever on long island (1971-1976).	clinical data from 124 rocky mountain spotted fever (rmsf) cases submitted by long island physicians and hospitals were compiled for the six-year period 1971-1976. this information was subsequently compared to two parameters: first, the geographic distribution of human cases and rickettsia-infected dermacentor variabilis (say), and, secondly, the human population dynamics in long island towns since 1950. despite an overall decline in the rate of suburbanization and population growth, cases of rm ...	1977	920726
suny at albany admits research violations.		1977	910154
a communitywide outbreak of giardiasis with evidence of transmission by a municipal water supply.	three hundred fifty residents of rome, new york, had laboratory-confirmed cases of giardiasis between 1 november 1974 and 7 june 1975. a random household survey showed an overall attack rate for giardiasis (defined as a diarrheal illness of 5 days or more) of 10.6%. a significant association was discovered between having giardiasis and using city water and between having illness and drinking 1 or more glasses of water a day. the presence of human settlements in the rome watershed area suggested ...	1977	907241
the human element in survey research.	this paper addresses itself to issues related to data collection in survey research with a community population. areas discussed related to practical human problems in conducting a community survey of a stratified random sample of people sixty-five years of age and over in new york city. some of these problems occur in most large scale community surveys, but some are a result of special features of this particular study. topics covered include difficulties encountered in obtaining interviews, ma ...	1977	873638
proficiency testing: purification of lactate dehydrogenase 1 and results of its use as a reference material in the new york state program.	highly purified human lactate dehydrogenase 1 has been used in an interlaboratory evaluation and improvement progran in clinical chemistry in new york state since 1971. although there are difficulties in determining and assigning the most nearly accurate values for test samples in the absence of a reference method and a reference material, we have minimized these difficulties by using human lactate dehydrogenase preparations purified as we describe here and suspended in the same matrix, and by u ...	1977	870250
court-legislated reform: a viable approach or paper victory?		1977	858599
cost and quality control of laboratory services: the new york city medicaid centralized laboratory proposal.	faced with constantly increasing costs for the provision of laboratory services to medicaid recipients, the new york city department of health last year attempted to implement a program to fundamentally restructure the organizational patterns and financing mechanisms of new york city's clinical laboratory industry. the program, based on competitive bidding, gave one laboratory in each of new york's five boroughs exclusive rights to process medicaid lab samples and replaced presently existing fee ...	1976	787699
clinical evaluation of neuraminidase monospecific (heqn2) recombinant influenza vaccine in children.	phased clinical trials were undertaken to evaluate the efficacy of neuraminidase specific recombinant (heqn2) inactivated influenza vaccine in a population of school children. groups of subjects were immunized under code, with influenza a2 port chalmer (h3n2), port chalmer neuraminidase recombinant (heqn2), and placebo vaccines (vaccine diluent) before the onset of a2 strain influenza epidemic in this population. preliminary results have provided the following information. immunization with comm ...	1976	782964
general washington and the patriot soldiers. they won a war with little food. a bicentennial study.	the troops in the first action of the american revolution in massachusetts were well provisioned through the efforts of joseph trumbull of connecticut, whom the second continental congress appointed commissary general, at general washingtion's request. the ration, as ordered, would have provided-by today's standards-more calories, twice as much protein, and adequate minerals and vitamins, except possible vitamin a and ascorbic acid. unfortunately, all items in the ration were seldom available to ...	1976	770557
the distribution and characterization of group b streptococci in new york state.	group b streptococcal isolates from bovine mastitis were classified according to the lancefield typing scheme. three types were found in new york state dairy herds; ia, ii and iii. the distribution within these types varies from area to area, however, on a state-wide basis ia is the most prevalent (69.6%) followed by type ii (16.7%) and type iii (10.1%). within a single herd one type predominants with only slight incidence of other types. attempts to determine distinguishing characteristics betw ...	1976	770075
a report from the del zio trial.		1978	721433
defining the comminity context for parent-child relations: the correlates of child maltreatment.	this report presents the results of studies designed to illustrate the use of child maltreatment report data as social indicators of the quality of life for families. it addresses the feedback function of family-support systems and links maltreatment to the overall balance of stresses and supports in the neighborhood context of families. this study focuses on the reported incidence of child abuse and neglect at 2 levels of neighborhood analysis within a single metropolitan county-20 neighborhood ...	1978	710189
the family life cycle: developmental crises and their structural impact on families in a community mental health center.	a typology for troubled families was developed based on the configuration of family members and the position of the identified patient within the family structure. this typology was investigated by surveying the demographic and clinical characteristics of 110 families of patients treated in a day hospital. four types or "constellations" were found in the sample population. the families in the four constellations differed significantly from one another in the gender, age, and diagnoses of the ide ...	1978	700069
natural 13c/12c ratio variations in human populations.	baseline data on the naturally occurring 13c/12c ratios of human tissue samples from several modern human populations are presented. isotope ratios were determined for endogenous tissue samples (brain, liver and lung) from 20 routine unselected autopsy cases of residents of long island, new york. comparable data were obtained from tissue samples from bergen, norway and lucerne, switzerland. average values of 13c ratios reported in units of delta13c(0/00) relative to the pdb carbonate standard we ...	1978	687783
limits to growth in world food production.	the dramatic increases in wheat yields that began in the mid-1930's in the united states will soon begin to level off. the favorable mix of genetics and technology that has characterized this era must build upon an ever higher yield base for the future. at the same time the residue of factors that can lower wheat yields includes a larger proportion of forces not easily shaped or controlled by man. an example is weather. the result is a natural yield ceiling that is already visible and that will ...	1978	663657
changes in the seasonality of human mortality: a medico-geographical study.		1978	644348
law-medicine notes. legal liability in clinical investigations.		1978	628412
training undergraduates for leadership of human sexuality discussion groups: issues and opportunities.		1977	608908
some new methods for the evaluation of medical school sex education curricula.	this study proposes new ways of evaluating medical school sex education curricula which may be used not only to determine the best educational methods, but also to understand what skills and competence are important for a doctor to have in order to assist patients with their sexual problems. since present evaluation tools are limited, the theoretical base from which human sexuality programmes are developed is based on unsupported personal judgement. good research with improved techniques is a re ...	1977	593177
bankrupt brooklyn hospital given hope for staying open.		1979	582816
babesia microti infection in man.		1977	578184
yersinia enterocolitica in oneida county, new york.	in a 7-month study during and after an outbreak of yersiniosis in oneida, n.y., a total of 963 specimens were examined for yersinia enterocolitica. of the 103 y. enterocolitica isolates recovered, 91 were from oneida county. sixty-two (60.2%) were from humans including 52 from oneida county. the isolates from the outbreak were mainly serotype 0:8, which on biotypnig proved to be niléhn type 2, wauters type 1, knapp and thal type 2. the rest of the isolates were distributed among various biotypes ...	1979	575321
prevalence of unique yersinia enterocolitica in the area of the mount sinai hospital, new york, n.y.	the incidence of infection due to yersinia enterocolitica is unknown in the united states as well as in a given geographic locale such as new york city. comparison of 10 y. enterocolitica strains recovered at nine hospitals in the new york city area to 22 isolated at the mount sinai hospital revealed striking differences in clinical presentation of disease, biochemical behavior of the isolates and their serological profiles. the 10 strains were from patients with 'classical syndromes', were bioc ...	1979	535396
short-term in vitro bioassays: applicability to air monitoring in the coal conversion and shale oil industries.	short-termbioassays such as that of ames and co-workers may be a practical method of monitoring industrial environments for the presence of biologically active and potentially hazardous materials. in general, these assays detect agents that cause damage to dna which may lead to mutations, cancer, birth defects and to other diseases. used to monitor industrial environments, such tests can indicate the presence of biologically active materials and can detect changes in the levels of these material ...	1979	517440
an epidemiologic study of the human bite.	the 892 human bites reported to the new york city department of health in 1977 were analyzed by time, place, and the victim's characteristics. the bites appeared to have a seasonality, increasing in march and exceeding the mean monthly average through august. the bite rate for the entire city, 10.7 per 100,000 population, was exceeded in 5 of the 10 brooklyn health districts; one of these districts reported a rate of 60.9 human bites per 100,000 population. most of the bites with identifiable lo ...	1979	515337
age and sensitivity to lead toxicity: a review.	during the past 20 years considerable attention has been focused on the epidemiologic features of childhood lead poisoning in the united states. large numbers of children with symptomatic intoxication, as well as those with incipient symptoms, were commonplace a decade ago for physicians working in inner-city hospitals. with the recent availability of improved screening techniques, as well as a variety of environmental control measures, the incidence of symptomatic lead poisoning in children has ...	1979	510238
veterinary medicine in new york state: overview of distribution patterns.	an understanding of the distributional patterns of veterinary practitioners in new york state can assist in optimizing veterinary services and opportunities. veterinarians have been arrayed by type of practice and location within counties and major land form regions. relationships between the number of practitioners and human and animal populations have been examined in these areas and show the inadequacy of basing veterinary needs on human population data. in contrast, large animal numbers show ...	1979	477320
human hexosaminidase isozymes. iv. effects of oral contraceptive steroids on serum hexosaminidase activity.	data from a mass screening program for identification of persons who are heterozygous for tay-sachs disease have been analyzed for the effects of oral contraceptive steroids on the activity in serum of hexosaminidase (hex) and the various hex isozymes. women using oral contraceptives show a significantly higher total serum hex activity, reflecting mainly an increase in the heat-stable hex isozyme (hex i), and a smaller increase in the heat-labile hex a than do women using no medications. the cha ...	1979	463955
sunlight and human cataracts.	studies of the cataractous lenses of humans in three different geographic locations indicate that where the ultraviolet components of sunlight are more intense, dark brown cataracts result at a higher frequency than in locations where they are weak. individuals exposed to sunlight regularly by virtue of their outdoor occupations seemed to develop this dark brown type of cataract much more frequently than those who work indoors. the biochemical characteristics of all brunescent cataracts were fou ...	1979	437948
human antirabies treatment in the united states, 1972.	data were examined on 965 persons treated in six states (delaware, florida, georgia, illinois, north dakota, and south carolina) and new york city in 1972 for possible rabies exposure. males 10-19 years were found to be the group at greatest risk, and exposures occurred most frequently during the warm months. dogs, other domestic animals, and wildlife were about equally responsible for human exposures in the six states, but 99% of the exposures in new york city involved dogs. antirabies postexp ...	1979	432411
ches: the man for all seasons.		1979	385864
hospice program; law, guidelines, and implementation.		1979	379717
the united states swine influenza immunization program: a new york city perspective.		1979	369639
john d. quackenbos, m.d. (1848-1926): a man for all seasons.		1978	369065
health care cost containment experiments: policy, individual rights, and the law.	in a climate of increasing pressure to contain health care costs, legislators and health services researchers from time to time have proposed experiments involving reductions in benefits currently authorized under the medicare and medicaid programs. this paper examines three court challenges to the conduct of such experiments in california, new york, and georgia. the rulings on the california and new york cases were in favor of continuing the experiments on the grounds that the secretary of heal ...	1978	365931
the background to the determination of the human chromosome number.		1978	345814
nutrition classics. the journal of biological chemistry 41: 97-109; 1920. protein requirement of maintenance in man and the nutritive efficiency of bread protein. by h. c. sherman.		1977	331146
presidential address. doctor, is this operation necessary?		1977	327841
salmonella in surface waters of central new york state.	six tributary streams and southern cayuga lake in central new york state were sampled for the presence of salmonella on swabs immersed for 4 days. of a total of 322 swabs, 39% yielded salmonellae. swabs were cultured in tetrathionate enrichment at 41.5 degrees c. isolations were made from brilliant green agar. salmonellae were isolated from many sites on the streams and from some lake sites. twenty-five serotypes (11 somatic antigen groups) and a distinct biotype of s. typhimurium (h2s negative) ...	1977	326183
human blood in new york city: then (1956).		1977	321058
prevalence and type of traumatic injuries to the anterior teeth of preschool children.		1979	297789
program evaluation as health services research.	evaluation of health program is necessary for more rational allocation of scarce resources. steps in evaluation include: 1)specification of the program goals, 2) description of the program, 3) definition and measurement of outcome, 4) assessment of intervening variables, 5) analysis of data, and 6) implementation of findings. examples from impirical evaluation studies are presented to illustrate one practical application of these steps. while the random controlled trial is a most powerful tool, ...	1978	281768
conversion reactions simulating guillain-barré paralysis following suspension of the swine flu vaccination program in the u.s.a.	the association of guillain-barré syndrome as a possible complication of swine flu inoculation created the potential for conversion reactions simulating this syndrome. upon termination of the swine flu vaccination program, a study was initiated in a prepaid health plan to identify and categorize such patients. an estimated 8000 adults were vaccinated and it was hypothesized that a large number of these patients would present to the health plan with conversion symptoms. however, only seven patien ...	1978	278603
human sparganosis. in northern united states.		1978	276692
influenza. surveillance report for "swine flu" scare year 1976.		1977	268501
human blood in new york city: now.		1977	265179
survey of human enterovirus occurrence in fresh and marine surface waters on long island.	a variety of surface water systems, including a lake, a creek, and two marine embayments, were analyzed on a monthly basis for indigenous human enteroviruses and coliform bacteria. findings are discussed in terms of the probable pollution sources to each system and their relationship to data from previous studies.	1979	229767
survey of human virus occurrence in wastewater-recharged groundwater on long island.	treated wastewater effluents and groundwater observation wells from three sewage recharge installations located on long island were assayed on a monthly basis for indigenous human enteroviruses and coliform bacteria for a period of 1 year. viruses were detected in groundwater at sites where recharge basins were located less than 35 feet (ca. 10.6 m) above the aquifer. results from one of the sites indicated the horizontal transfer of viable viruses through the groundwater aquifer.	1978	211935
viral meningitis. epidemic in children on lower east side of new york city.		1978	205818
the seattle virus watch. vii. observations of adenovirus infections.	the following findings were made from observations of adenovirus (av) infections in seattle vw families, 1965-1969, which extended the 1961-1965 new york vw studies: that infections are predominantly enteric, may be abortive or invasive and followed by persistent intermittent excretion was confirmed. that such excretion is most characteristic of types 1, 2, 3 and 5 viruses may explain why these types were usually endemic. however, since observed duration of excretion was not increased despite a ...	1977	192073
seroepidemiologic survey of varicella: value of specific fluorescent antibody test.	the sensitive varicella-zoster fluorescent antibody to membrane antigen (v-z fama) test was used in a seroepidemiologic survey of two outbreaks of varicella involving 30 children. the attack rate of varicella based on clinical observations alone was 60%. the attack rate based on clinical and serological observations lay between 78% and 82%, after excluding those children who had detectable antibody at the time of exposure. no subclinical varicella infection was observed in this small series of p ...	1975	172853
hbs-ag-negative hepatitis in a hemodialysis unit: relation to epstein-barr virus.	eleven of 40 patients in a hemodialysis unit had clinical or biochemical evidence of hepatitis during a five-week period. the clinical disease was mild, being limited solely to dialysis patients. epidemiologic investigation indicated that the incubation period was between 17 and 35 days and that 10 of 11 patients had been exposed to a single venous-pressure monitor before onset. dried blood and evidence of blood reflux up the venous-pressure gauge suggested that cross-contamination of the blood ...	1975	171573
total pancreatectomy with primary mesenteric vascular reconstruction.	total pancreaticoduodenectomy with resection of the superior mesenteric artery and vein was performed in a sixty-two year old man with islet cell carcinoma of the pancreas. arterial reconstruction was accomplished with an aortomesenteric interposition dacron graft. the venous system was reanastomosed primarily, the infrapancreatic superior mesenteric vein to the portal vein in the hepatic hilum. this procedure, although it did not result in long-term survival, demonstrates the technical feasibil ...	1975	165739
the ratio of de novo unbalanced translocation to 47, trisomy 21 down syndrome. a new method for human mutation surveillance and an apparent recent change in mutation rate resulting in human interchange trisomies in one jurisdiction.	the down syndrome phenotype may be associated with, among other genotypes, an unbalanced robertsonian translocation producing an "interchange trisomy" with 46 chromosomes, or 47, trisomy 21. translocations, like specificlocus point mutations, result from a direct change in structural chromosome elements. in contrast 47, trisomy 21 results from meiotic non-disjunction. mutation rates for interchange trisomies may be followed indirectly by determining the ratio of instances of down syndrome associ ...	1978	152869
irs, hew threaten triple-a bonds.		1978	152403
trends in the distribution of staphylococcus aureus phage patterns in new york state during 1966-1975.	the phage patterns of 15 790 s. aureus isolates collected from human sources in new york state (exclusive of new york city) during the 10-year period 1966-1975 were analysed. the results showed changes in the distribution of phage groups and a steadily increasing incidence of nontypable s. aureus.	1976	142587
immunological relationships of long island isolates of babesia microti.	studies to detect strain differences among two rodent-derived and one human-derived babesia microti isolates from long island were undertaken, using various methods. superinfection experiments using the homologous and heterologous isolates showed cross-protection. all hamsters were resistant to superinfection challenges of increasing dosages of both the homologous and heterologous isolates. attempts to infect other laboratory animals with the long island isolates of b. microti were successful in ...	1979	88904
hunter and venereal disease.		1979	85098
the brain death criterion of human death. an analysis and reflections on the 1977 new york conference on brain death.		1979	42534